Evolution by tumor neofunctionalization [electronic resource] : the role of tumors in the origin of new cell types, tissues and organs
- by Andrei P. Kozlov.
- Burlington : Elsevier Science, 2014.
- Physical description
- 1 online resource (248 pages)
- Kozlov, Andrei P.
- 1. The modern synthesis of evolutionary biology and the health sciences
- 2. Evolution and pathology
- 3. The widespread occurrences of tumors in multicellular organisms
- 4. Features of tumors that could be used in evolution
- 5. Tumors might participate in the evolution of ontogenesis
- 6. Tumors that might play a role in evolution
- 7. Tumors that have played a role in evolution
- 8. The general principles and molecular mechanism in the orgin of novel genes
- 9. The origin of evolutionary novel genes and the evolution of new functions and structural complexity of multicellular organisms
- 10. The orgin of new cell types, tissues and organs by tumor neofunctionalization
- 11. Experimental confirmation of nontrivial predictions of evolution by the tumor neofunctionalization hypothesis
- 12. Other evidence supporting the positive evolutionary role of tumors and the hypothesis of evolution by tumor neofunctionalization.
- Publisher's Summary
- Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. * Covers the role that tumors might play in evolution.* Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more.
(source: Nielsen Book Data)9780128001653 20160612
- Publication date
- Available in another form
- Print version: Kozlov, Andrei P. Evolution by Tumor Neofunctionalization : The Role of Tumors in the Origin of New Cell Types, Tissues and Organs. Burlington : Elsevier Science, ©2014 ( 9780128001653 )
- 9780128004982 (electronic bk.)
- 0128004983 (electronic bk.)