Introductory mass spectrometry
- Stephen Shrader.
- Second edition.
- Boca Raton : CRC Press, 
- Copyright notice
- Physical description
- 1 online resource : text file, PDF
- Shrader, Stephen R., 1942-
- Includes bibliographical references and index.
- INTRODUCTION What is Mass? Fragmentation The Mass Spectrometer sample Introduction Ionization Mass Separation Resolution Ion Detection Data Presentation ELECTRON IONIZATION Ion Formation Types of Ions Molecular Ion Fragment Ion Multiply Charged Ion Molecular Ions Isotope Peaks Group 1 Group 2 Group 3 Multiply Charged Ions Neutral Fragments Basic Mass Spectral Reactions Introduction Simple cleavage Multicenter fragmentations Expulsion of Stable Neutral Fragments Interpreting EI Mass Spectra ACCURATE MASS MEASUREMENT Introduction Mass Calibration Elemental Compositions Applications MODERN TECHNIQUES Introduction Gas Chromatography-Mass Spectrometry Introduction Applications Low Energy Ionization Low Electron Energy Field Ionization Fast Atom Bombardment Photoionization Chemical Ionization Electrospray Ionization Atmospheric Pressure Chemical Ionization Matrix-Assisted Laser Desorption Ionization Direct Analysis in Real Time Liquid Chromatography-Mass Spectrometry Introduction Applications Appendix I Answers to Problems Index.
- (source: Nielsen Book Data)9781466595859 20160612
- Publisher's Summary
- Mass spectrometry has played an integral part in the study of organic molecular structures for more than 50 years, offering significant information from small amounts of sample. The mass spectrum produced by electron impact ionization presents a pattern of peaks that can often give definitive structural information about an unknown compound. Introductory Mass Spectrometry, Second Edition guides readers in the understanding and recognition of those patterns, discussing mass spectra in terms that are familiar to chemists. It provides a basis for chemists to interpret mass spectra to solve particular structural problems. The Second Edition has been updated with modern techniques and data handling. Beginning with an introduction to the principles and instrumentation, it then sequentially explains the processes that occur in the mass spectrometer following ionization. The book is unique in the large number of mass spectra presented and provides examples of mass spectra from a wide variety of organic chemicals, concentrating on the relationships between fragmentation patterns, common chemical reactions, and chemical structures. The book also discusses mass spectra obtained with softer ionization techniques, which provide definitive information regarding molecular weights. The text describes mass spectra produced by electron ionization, discussing how the spectral peak pattern relates to molecular structure. It details the use of high-resolution and accurate mass measurement to determine elemental composition of ions in order to identify unknown substances. The book also introduces some of the recent techniques that can be employed to extend the usefulness of mass spectrometry to high molecular weight substances and more polar substances. It includes examples and problems representing a cross section of organic chemistry to help readers integrate the principles presented.
(source: Nielsen Book Data)9781466595859 20160612
- Mass spectrometry.
- Publication date
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- Also available in print format.
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- Print version: ( 9781466595842 (paperback) )
- 9781466595859 (e-book : PDF)
- 146659585X (e-book : PDF)