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• Preface--
• 1. The structure of the enteropathogenic Escherichia coli type III-secretion apparatus Elizabeth A. Creasey and Gad Frankel--
• 2. Vaccinia virus movement in cells Geoffrey L. Smith--
• 3. Induction of pro-inflammatory signals by Salmonella-epithelial cell interactions Abigail N. Blakey and Edouard E. Galyov--
• 4. Modulation of Toll-like receptor signalling by viruses Andrew Bowie--
• 5. Enteropathogenic Escherichia coli (EPEC) and its effector molecules Brendan Kenny and Jonathan Warawa--
• 6. Lipid-protein interactions in enveloped virus entry, protein traffic, and assembly Min Li, Andrei N. Vzorov, Armin Weidmann, Chinglai Yang and Richard W. Compans--
• 7. Legionella pneumophila: a model system to study bacterial modulation of phagosome transport Craig R. Roy--
• 8. Regulation of membrane fusion processes in eukaryotic cells: what can we learn from pathogenic mycobacteria? Jean Pieters--
• 9. Molecular and cellular mechanisms of action of the VacA and HP-NAP virulence factors of Helicobacter pylori Marina de Bernard and Cesare Montecucco--
• 10. Who is controlling the inflammatory response in shigellosis - bacteria or host? Jonathan D. Edgeworth and Philippe J. Sansonetti--
• 11. Cell death on demand: herpes simplex viruses and apoptosis Joshua Munger, Guoying Zhou and Bernard Roizman--
• 12. Apoptosis in Shigella and Salmonella infections Volker Brinkmann and Arturo Zychlinsky--
• 13. Setting up a nest and maintaining it: intracellular replication of Legionella pneumophila Ralph R. Isberg--
• 14. Entry of Listeria monocytogenes into mammalian cells: from cell biology to physiopathology P. Cossart-- Index.
• (source: Nielsen Book Data)

Microbes have co-evolved with other organisms for eons, to the extent that some are so acquainted with host cell biology that they subvert key cellular processes with unrivalled precision. Pathogenic bacteria and viruses, for example, are extremely adept at intercepting host signal transduction pathways, re-routing protein traffic, remodelling the cytoskeleton and influencing host cell differentiation or death. Symbionts and commensal organisms, too, have evolved sophisticated strategies to derive benefit from the host environment without eliciting responses that compromise their viability. This volume reviews this exciting new discipline, reflecting both the recent explosion of knowledge and the wider insights into fundamental cellular processes that are provided. The authors, chosen for their contributions to the field, cover all the salient aspects using a range of model systems.
(source: Nielsen Book Data)

• Preface--
• 1. Adaptive immune responses J. L. Whitton--
• 2. T-cell responses and dengue haemorrhagic fever G. Screaton and J. Mongkolsapaya--
• 3. The immune response to human immunodeficiency virus type 1 (HIV-1) E. Turnbull and P. Borrow--
• 4. Persistent RNA virus infections C. M. Dixon, L. Breakwell, G. Barry and J. K. Fazakerley--
• 5. Exotic virus pathogenesis S. Nichol--
• 6. Molecular approaches to the pathogenesis of feline coronaviruses C. Dye and S. Siddell--
• 7. The transmissible spongiform encephalopathies J. C. Manson and R. M. Barron--
• 8. Influenza virus pathogenicity R. G. Webster, A. S. Lipatov and E. Hoffmann--
• 9. RNAi as an antiviral mechanism and therapeutic approach R. P. van Rij and R. Andino--
• 10. Neurons and host immunity conspire to maintain herpes simplex virus in a latent state M. L. Freeman, V. Decman and R. L. Hendricks--
• 11. Hepatitis C virus disruption of interferon signalling pathways and evasion of innate intracellular antiviral defences S. M. Lemon and K. Li--
• 12. Human papillomaviruses and their effects on cell cycle control and apoptosis L. Gray, C. Jolly and C. S. Herrington--
• 13. Intracellular antiviral defence mechanisms: the power of interferon-regulated restriction factors O. Haller, F. Weber and G. Kochs--
• 14. Poxvirus immune evasion A. Alcami--
• 15. Evasion of host defence systems by African swine fever virus L. K. Dixon--
• 16. Murid herpesvirus 4 as a model for gammaherpesvirus pathogenesis J. P. Stewart, D. Hughes, L. Roaden and B. Ebrahimi-- Index.
• (source: Nielsen Book Data)

Virus and prion diseases remain a major public health threat, in both developed and developing countries. The worldwide HIV pandemic is but one example of a newly emerged virus disease; other potential threats come from exotic viruses such as SARS, Ebola and Hantaan viruses. Older human viruses such as influenza, papilloma, herpes and the hepatitis viruses still cause major health problems. Furthermore, as well as causing acute infections, some viruses may also establish persistent infections which can lead to the development of chronic diseases, including cancer. This symposium book covers central factors that influence the pathogenicity of virus and prion infections. Topics range from innate and adaptive immune responses and virus evasion of host defences to details of selected virus host interactions, including those involving dengue virus, HIV, influenza viruses, coronaviruses, hepatitis C virus, herpesviruses, papillomaviruses, African swine fever virus and poxviruses.
(source: Nielsen Book Data)

• Editor's preface--
• 1. Microbial reaction to environment: bacterial stress responses revisited in the genomic-proteomic era F. C. Neidhardt--
• 2. Gene variation and gene regulation in bacterial pathogenesis D. Hood and R. Moxon--
• 3. DNA topology and regulation of bacterial gene expression C. J. Dorman-- DNA rearrangements and regulation of gene expression I. C. Blomfield--
• 4. Structures of multisubunit DNA-dependent RNA polymerases R. D. Finn, E. V. Orlova, M. van Heel and M. Buck--
• 5. The ECF sigma factors of Streptomyces coelicolor A3(2) M. S. B. Paget, H-J. Hong, M. Bibb and M. J. Buttner--
• 6. Secrets of bacterial transcription initiation taught by the Escherichia coli FNR protein D. Browning, D. Lee, J. Green and S. Busby--
• 7. What can be learned from the LacR family of Escherichia coli? B. Muller-Hill--
• 8. Regulation of the L-arabinose operon in Escherichia coli R. Schleif--
• 9. Transcription termination control in bacteria T. M. Henkin--
• 10. Antisense RNAs in programmed cell death K. Gerdes--
• 11. Control of signal transduction in the sporulation phosphorelay J. A. Hoch--
• 12. A stranglehold on a transcriptional activator by its partner regulatory protein - the case of the NifL-NifA two-component regulatory system R. Dixon--
• 13. Is anybody here? Cooperative bacterial gene regulation via peptide signals between Gram-positive bacteria D. A. Morrison--
• 14. Quorum sensing in Gram-negative bacteria: global regulons controlled by cell-density-dependent chemical signalling N. A. Whitehead, A. K. P. Harris, P. Williams and G. P. C. Salmond-- Index.
• (source: Nielsen Book Data)

DNA sequencing has provided a wealth of information on the genetic material stored in bacterial genomes. The use of DNA arrays and proteomics will transform the scale of our ability to describe the patterns of gene expression as bacteria respond to their environments. However, the ability to control bacteria in a clinical context or exploit them in industrial or environmental contexts also depends on understanding the regulatory mechanisms which connect input experience to output response at the genetic level. This book deals with our current knowledge of the circuits and networks that govern bacterial gene expression - from the single gene to the whole genome - and which provide the framework for explaining the data from the post genomics revolution.
(source: Nielsen Book Data)

• Editors' preface--
• 1. The evolution of prokaryotes Erko Stackebrandt and Carl R. Woese--
• 2. The origin and early evolution of the eukaryotic cell T. Cavalier-Smith--
• 3. Sporulation in evolution Ian W. Dawes--
• 4. DNA rearrangements and evolution John Cullum and Heinz Saedler--
• 5. tRNA splicing in yeast J. Abelson, G. Knapp, C. L. Peebles, R. C. Ogden, P. F. Johnson and J. D. Johnson--
• 6. The evolution of ferredoxin and superoxide dismutase in microorganisms K. K. Rao and R. Cammack--
• 7. The evolution of metabolic pathways Hans Krebs--
• 8. The evolution of metabolic regulation Simon Baumberg--
• 9. The evolution of membrane-bound bioenergetic systems: the development of vectorial oxidoreductions Peter B. Garland--
• 10. Shift and drift in influenza viruses W. Min Jou, M. Verhoeyen, R. -X. Fang, R. Devos, D. Huylebroeck and W. Fiers--
• 11. Evolution of antigenic variation in the salivarian trypanosomes M. J. Turner and J. S. Cordingley--
• 12. Summarizing remarks J. R. S. Fincham-- Index.
• (source: Nielsen Book Data)

This volume is a sequel to the Society for General Microbiology's Symposium 24 Evolution in the Microbial World published in 1974. That account was the first work devoted wholly to microbial evolution. Rapid progress in this area has resulted in a second symposium volume on the subject. Both molecular and cellular aspects of evolution are considered as well as the evolution of metabolic systems and evolution within two groups of pathogens.
(source: Nielsen Book Data)

• List of contributors-- Preface--
• 1. An overview of biofilms as functional communities J. Wimpenny--
• 2. Initial microbial adhesion events: mechanisms and implications H. J. Busscher and H. C. van der Mei--
• 3. Physiological events in biofilm formation D. G. Davies--
• 4. Environmental and genetic factors influencing biofilm structure P. Stoodley, L. Hall-Stoodley, J. D. Boyle, F. Jorgensen and H. M. Lappin-Scott--
• 5. Coaggregation and coadhesion in oral biofilms P. E. Kolenbrander, R. N. Andersen, K. M. Kazmerzak and R. J. Palmer, Jr--
• 6. Cohesiveness in biofilm matrix polymers H.-C. Flemming, J. Wingender, C. Mayer, V. Koerstgens and W. Borchard--
• 7. Microbial detachment from biofilms G. F. Moore, B. C. Dunsmore, S. M. Jones, C. W. Smejkal, J. Jass, P. Stoodley and H. M. Lappin-Scott--
• 8. Modelling and predicting biofilm structure C. Picioreanu, M. C. M. van Loosdrecht and J. J. Heijnen--
• 9. Microbial community interactions in biofilms P. D. Marsh and G. H. W. Bowden--
• 10. Microbial communities: aggregates of individuals or co-ordinated systems S. Molin, J. A. J. Haagensen, K. B. Barken and C. Sternberg--
• 11. Gene transfer in biofilms L. J. Ehlers--
• 12. Population dynamics in microbial biofilms A. J. McBain, D. G. Allison and P. Gilbert--
• 13. Biodegradation by biofilm communities G. M. Wolfaardt, D. R. Korber, S. Karthikeyan and D. E. Caldwell--
• 14. Biofilms and prosthetic devices R. Bayston--
• 15. Biofilms: problems of control D. G. Allison, A. J. McBain and P. Gilbert--
• 16. Biofilms in the New Millennium: musings from a peak in Xanadu J. W. Costerton-- Index.
• (source: Nielsen Book Data)

The study of biofilm considers the close association of micro-organisms with each other at interfaces and the consequent physiological adaptation to the proximity of other cells and surfaces. As such it is relevant to a variety of disciplines, including medicine, dentistry, bioremediation, biofouling, water technology, engineering and food science. Although the habitats studied, and their associated cellular communities, differ widely, some common elements exist such as method of attachment, coadhesion, regulation of biofilm phenotype and biofilm architecture. This book aims to distil the common principles of biofilm physiology and growth for all interested disciplines. It will appeal to the specialist biofilm researcher as well as to students wishing to introduce themselves to the topic.
(source: Nielsen Book Data)

• List of contributors-- Preface--
• 1. An overview of biofilms as functional communities J. Wimpenny--
• 2. Initial microbial adhesion events: mechanisms and implications H. J. Busscher and H. C. van der Mei--
• 3. Physiological events in biofilm formation D. G. Davies--
• 4. Environmental and genetic factors influencing biofilm structure P. Stoodley, L. Hall-Stoodley, J. D. Boyle, F. Jorgensen and H. M. Lappin-Scott--
• 5. Coaggregation and coadhesion in oral biofilms P. E. Kolenbrander, R. N. Andersen, K. M. Kazmerzak and R. J. Palmer, Jr--
• 6. Cohesiveness in biofilm matrix polymers H.-C. Flemming, J. Wingender, C. Mayer, V. Koerstgens and W. Borchard--
• 7. Microbial detachment from biofilms G. F. Moore, B. C. Dunsmore, S. M. Jones, C. W. Smejkal, J. Jass, P. Stoodley and H. M. Lappin-Scott--
• 8. Modelling and predicting biofilm structure C. Picioreanu, M. C. M. van Loosdrecht and J. J. Heijnen--
• 9. Microbial community interactions in biofilms P. D. Marsh and G. H. W. Bowden--
• 10. Microbial communities: aggregates of individuals or co-ordinated systems S. Molin, J. A. J. Haagensen, K. B. Barken and C. Sternberg--
• 11. Gene transfer in biofilms L. J. Ehlers--
• 12. Population dynamics in microbial biofilms A. J. McBain, D. G. Allison and P. Gilbert--
• 13. Biodegradation by biofilm communities G. M. Wolfaardt, D. R. Korber, S. Karthikeyan and D. E. Caldwell--
• 14. Biofilms and prosthetic devices R. Bayston--
• 15. Biofilms: problems of control D. G. Allison, A. J. McBain and P. Gilbert--
• 16. Biofilms in the New Millennium: musings from a peak in Xanadu J. W. Costerton-- Index.
• (source: Nielsen Book Data)

The study of biofilm considers the close association of micro-organisms with each other at interfaces and the consequent physiological adaptation to the proximity of other cells and surfaces. As such it is relevant to a variety of disciplines, including medicine, dentistry, bioremediation, biofouling, water technology, engineering and food science. Although the habitats studied, and their associated cellular communities, differ widely, some common elements exist such as method of attachment, coadhesion, regulation of biofilm phenotype and biofilm architecture. This book aims to distil the common principles of biofilm physiology and growth for all interested disciplines. It will appeal to the specialist biofilm researcher as well as to students wishing to introduce themselves to the topic.
(source: Nielsen Book Data)