• 1. Traces and Tracers - The Limits of Toxicology.- 2. A Rapid 2D TLC Screening Procedure for Drugs in Cases of Acute Drug Overdosage.- 3. Selection of Methods for Systematic Toxicological Analysis.- 4. Immunoassays in Forensic Toxicology.- 5. Insulin Murders: Isolation and Identification by Radioimmunoassay After Several Months of Inhumation.- 6. Clozapin, a Fatal Case.- 7. The Detection of Heavy Metals from Biological Material by Gas-liquid-chromatography via the Diethyldithiocarbamates.- 8. Determination of 8-methoxypsoralen in Human Serum and Suction Blister Fluid.- 9. Isolation of Drugs from Blood and Tissue Homogenates using Thin Channel Ultrafiltration.- 10. Analysis of Autopsy Samples for the Detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin by High Resolution GC-MS.- 11. Rapid Analytical Method for Alcohol in Biological Fluids Using the Alcolmeter AE-Dl.- 12. Fuel Cell Measurement of Breath/blood Alcohol.- 13. Extractive Dialysis.- 14. A Road Traffic Act Drug Screening System - A Survey of Results.- 15. Toxicological Determination of Heroin and Morphine in Urine and Blood of Man.- 16. Analysis and Disposition of Dextromoramide in Body Fluids.- 17. GLC and TLC of Some Pethidine-like Narcotics and their Metabolites.- 18. The Abuse of Preparations containing Dipipanone and Cyclizine-- Analytical Aspects and their Interpretation.- 19. A Benzodiazepine Survey of Urine Samples Collected for the Purposes of the Road Traffic Act.- 20. A Specific Method for the Analysis of Buformin in Pre- and Post-mortem Human Material.- 21. The Comparison of TLC with GLC and GC/MS as well as TLC/GLC as Screening Methods for Synthetic, Chemical Stimulating Laxatives in Case of Abuse.- 22. The Screening of Pesticides in Forensic Toxicology.- 23. The Relevance of Plasma Paraquat Assays.- 24. Illicit Methadone - Laboratories in Berlin.- 25. Analytical Estimation of Indomethacin in Plasma by Gas Chromatography - Mass Fragmentography.- 26. On-line Identification Program of Poisonous and Hallucinogenic Mushrooms.- 27. Identification of Amphetamine, Mefenorex and Fencanfamin in Three Cases of Doping.- 28. The Detection of Coumarin Anticoagulants in Biological Fluids by Gas Liquid Chromatography-Mass Spectrometry.- 29. A Simple Gas-Liquid Chromatographic Assay for the Measurement of a New Antiarrhythmic Drug Lorcainide and its Metabolite Norlorcainide in Plasma.- 30. Rapid High-performance Liquid Chromatographic Method for the Measurement of Temazepam in Blood-plasma or Serum.- 31. Mercury Intoxications During Application of Pharmaceutical Preparations.- 32. Experience with Enzymatic Deproteination in General Toxicological Case Work.- 33. The Analysis of Volatiles in Blood from Fire Fatalities.- 34. Chromatographic Detection of Some Drugs of Toxicological Interest Using a Method for Amphetamine Identification.- 35. The Analysis of Blood in Cases of Suspected Solvent Abuse ("glue sniffing") with a Review of Results Obtained During the Period October 1977 to July 1979.- 36. The Detection of Drugs in Greyhound Urine by EMIT and TLC.- Author Index.
• (source: Nielsen Book Data)9781468414806 20160619

Forensic toxicology has progressed rapidly and diversified greatly in recent years. The members of the International Association of Forensic Toxicologists provide a valuable service through the association's bulletin. In its pages members hear of new poisons as they are encountered and the analytical techniques used to deal with them. There is a wealth of information in the form of case reports which is used to assist with the interpretation of the results. Each year the members have the opportunity of meeting in Europe. In 1979 the chosen venue was the University of Glasgow and the meeting was hosted by the Department of Forensic Medicine and Science. The department was established by Royal Charter in 1839 within a few years of the beginning of the modern approach to toxicology. In those early years the function of the department was to teach forensic medicine and toxicology. Today the department has become a recognised centre for the teaching of forensic medicine. The toxicology section has expanded greatly to provide the best forensic and environmental toxicology in Scotland. Inorganic analytical facilities are available for the investigation of metallic poisons by atomic absorption spectrometry, neutron activation analysis, X-ray fluorescence and anodic stripping voltametry. Organic analytical toxicology is pursued using gas chromatography, high performance liquid chromatography, immunoassays, and gas chromatography mass spectrometry. Apart from the normal research and routine investigations of a toxicological laboratory the department specialises in the investigation of fire related deaths, solvent abuse (glue sniffing) and trace element studies in human subjects.
(source: Nielsen Book Data)9781468414806 20160619

• The history of drug-facilitated crimes in france
• Epidemiology of drug-facilitated crimes and drug-facilitated sexual assaults
• Drugs involved in drug-facilitated crime: pharmacological aspects
• Ethanol- and drug-facilitated crime
• Memory impairment after drug-facilitated crimes
• Cannabis and drug-facilitated crimes
• Drugs involved in drug-facilitated crimes (DFC), analytical aspects: 1, blood and urine
• Drugs involved in drug-facilitated crimes (dfc), analytical aspects: 2, hair
• Case reports in drug-facilitated crimes: from A for alprazolam to Z for zopiclone
• The specific problem of children and old people in drug-facilitated crime cases
• Clinical aspects of drug-facilitated sexual assault.

Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology. * Brings together the latest research on the toxicological analysis of drug-facilitated crimes (DFC), with real-life case studies* Provides up-to-date analytical techniques for determining toxicity levels in blood, urine, and hair* Covers all types of toxicants involved in DFC, including alcohol, cannabis, MDMA, and a wide variety of pharmaceuticals.
(source: Nielsen Book Data)9780124167483 20160613

• pt. 1. Toxicology
• pt. 2. Forensic medicine.

• PART 1. TOXICOLOGY
• CHAPTER 1. OPIOIDS: METHODS OF FORENSIC ANALYSIS
• CHAPTER 2. CURRENT METHODS FOR THE SEPARATION AND ANALYSIS OF COCAINE ANALYTES
• CHAPTER 3. AMPHETAMINES
• CHAPTER 4. HALLUCINOGENS
• CHAPTER 5. CANNABINOIDS ANALYSIS: ANALYTICAL METHODS FOR DIFFERENT BIOLOGICAL SPECIMENS
• CHAPTER 6. SEDATIVES AND HYPNOTICS Thomas
• CHAPTER 7. ANTIDEPRESSANTS AND ANTIPSYCHOTICS
• CHAPTER 8. NON-OPIOID ANALGESICS
• CHAPTER 9. OTHER THERAPEUTIC DRUGS OF FORENSIC RELEVANCE
• CHAPTER 10. MUSHROOM TOXINS Ilkka Ojanper̃
• CHAPTER 11. FORENSIC SCREENING BY GAS CHROMATOGRAPHY
• CHAPTER 12. FORENSIC SCREENING WITH GC-MS
• CHAPTER 13. HIGH PERFORMANCE LIQUID CHROMATOGRAPHY IN FORENSIC TOXICOLOGICAL ANALYSIS
• CHAPTER 14. FORENSIC SCREENING WITH LIQUID CHROMATOGRAPHYMASS SPECTROMETRY
• CHAPTER 15. FORENSIC TOXICOLOGICAL SCREENING WITH CAPILLARY ELECTROPHORESIS AND RELATED TECHNIQUES
• CHAPTER 16. HPLC-ICP-MS SCREENING FOR FORENSIC APPLICATIONS
• CHAPTER 17. ANALYTICAL MARKERS OF ACUTE AND CHRONIC ALCOHOL CONSUMPTION
• CHAPTER 18. TOXICOLOGICAL ASPECTS OF HERBAL REMEDIES
• CHAPTER 19. DRUGS AND DRIVING
• CHAPTER 20. UNCONVENTIONAL SAMPLES AND ALTERNATIVE MATRICES
• Chapter 21. DOPING SUBSTANCES IN HUMAN AND ANIMAL SPORT
• CHAPTER 22. PHARMACOGENOMICS FOR FORENSIC TOXICOLOGY IN ENABLING PERSONALIZED MEDICINE
• CHAPTER 23. ASPECTS OF QUALITY ASSURANCE IN FORENSIC TOXICOLOGY
• PART 2. FORENSIC CHEMISTRY
• CHAPTER 24. EXPLOSIVES
• CHAPTER 25. CHEMICAL WARFARE AGENTS
• CHAPTER 26. FORENSIC ANALYSIS OF FIRE DEBRIS
• CHAPTER 27. WRITING MEDIA AND DOCUMENTS
• PART 3. FORENSIC IDENTIFICATION OF INDIVIDUALS AND BIOLOGICAL TRACES
• Chapter 28A. FORENSIC DNA TYPING TECHNOLOGIES: A REVIEW
• Chapter 28B. MITOCHONDRIAL DNA: FUTURE CHALLENGES IN FORENSIC GENETICS
• Chapter 28C. THE HUMAN Y-CHROMOSOME
• MALE-SPECIFIC POLYMORPHISMS AND FORENSIC GENETICS.

The book presents the applications of separation methods, manly chromatography, in forensic practice. The first part, devoted to forensic toxicology, contains reviews on forensic relevant groups of compounds, like: Opiate agonists, cocaine, amphetamines, hallucinogens, cannabinoids, sedatives and hypnotics, antidepressive and antipsychotic drugs, analgesics, antidiabetics, muscle relaxants, and mushroom toxins. In these parts, the preliminary immunochemical tests were also included, together with separation methods. Screening procedures used in forensic toxicology were presented in separate chapters on forensic screening with GC, GC-MS, HPLC, LC-MS, CE, and LC-ICP-MS. In the part on actual and emerging problems of forensic toxicology, following chapters were included: Analytical markers of alcohol abuse, toxicological aspects of herbal remedies, drugs and driving, analysis in alternative matrices, doping analysis, pharmacogenomics in forensic toxicology, and quality assurance.The second part presents application of separation methods in forensic chemistry, and comprises chapters on: Explosives, chemical warfare agents, arson analysis, and writing media. Third part on forensic identification contains chapter on forensic genetics. All chapters are written up-to-date and present specific information up to 2006. The authors of each chapter are known not only from their scientific activity, but are also reputed experts, proven in everyday forensic casework. This title features: wide spectrum of topics; up-to-date presentation of topics; data in comparative mode; and special stress on screening procedures.
(source: Nielsen Book Data)9780444522146 20160528

• Part I: Forensic Toxicology: Illicit Drugs. Opiate agonists (M.J. Bogusz). Introduction. Solid-phase extraction as a separation technique applied for isolation of opiates from biosamples. Papaver somniferum as a source of opiates. Heroin and associated illicit opiate formulations. Morphine-- therapeutic drug and heroin metabolite. Other opiate agonists. Concluding summary. Abbreviations. References. Current Methods for the Separation and Analysis of Cocaine Analytes (R.A. Jufer et al.). Introduction. Current methods for the determination of cocaine. Perspectives. List of abbreviations. References. Amphetamines (J.T. Cody). Introduction. Extraction. Derivatization. Gas chromatography. Liquid chromatography. Alternative techniques. Interpretation of analytical results. Conclusion. Abbreviations. References. Hallucinogens (J.T. Cody). Introduction. Lysergic acid diethylamide (LSD). Mescaline. Psilocybin. Phencyclidine (PCP). Conclusion. Abbreviations. References. Cannabinoids Analysis: Analytical Methods for Different Biological Specimens (M.A. ElSohly, M. Salem). Introduction. Analysis of cannabinoids in urine. Analysis of cannabinoids in blood. Analysis of cannabinoids in hair. Analysis of cannabinoids in meconium. Other biological specimens. Autopsy materials. Analysis of cannabinoids in crude cannabis preparations. Concluding remarks. References. Therapeutic Drugs. Sedatives and Hypnotics (T. Kraemer, H.H. Maurer). Introduction. Barbiturates. Benzodiazepines. Zopiclone and zolpidem. Diphenhydramine. Other sedatives and hypnotics. Concluding summary and perspectives. References. Antidepressants and Antipsychotics (D.R.A. Uges, J.M.H. Conemans). Introduction. Analytical techniques. HPLC chromatography. Gas chromatography. Thin-layer chromatography. Micellar electrokinetic capillary chromatography (MECC or MEKC) and capillary electrophoresis (CE). Concluding remarks. List of abbreviations. Unlinked references. References. Non-Opioid Analgesics (T. Kraemer, H.H. Maurer). Introduction. Paracetamol. Acetylsalicylic acid. Non-steroidal anti-inflammatory drugs (NSAIDs). Pyrazole derivatives. Concluding summary and perspectives. References. Other Therapeutic Drugs of Forensic Relevance (Cardiac Glycosides, Antiarrhythmics, Oral Antidiabetics and Muscle Relaxants) (W. E. Lambert, A.P. De Leenheer). Introduction. Cardiac glycosides. Antiarrhythmics. Oral antidiabetics. Muscle relaxants. Concluding summary. References. Other Topics. Enantioselective Liquid Chromatographic Analysis of Drugs in Forensic Science (S.H.Y. Wong). Introduction - chiral pharmacology: basic principles and current understandings. Enantiomeric liquid chromatographic analysis. Validation of a chiral HPLC assay. Indirect approaches and column switching. Direct approaches - seven major types of chiral stationary phases: mechanisms of enantiomeric separations and examples. Guidelines for clinical chiral drug analysis. Conclusions. Dedication. Abbreviations. Acknowledgment. References. Environmental Poisons (Mushroom Toxins) (I. Ojanpera). General introduction. Introduction. Amatoxins. Orellanine. Other toxins. References. Environmental Poisons Toxins of Freshwater Cyanobacteria(Blue-Green Algae) (J. Meriluoto). Introduction. Microcystins and nodularins. Cylindrospermopsin. Anatoxin-a. Anatoxin-a(s). Saxitoxins and other PSP toxins. Concluding remarks. References. Pesticides (I. Ojanpera). Introduction. Screening for pesticides. Paraquat and diquat. Rodenticides. References. Analysis of Chemicals Related to the Chemical Weapons Convention by GC (O. Kostiainen). Introduction. Chemical weapons. Sample preparation. Screening methods. Unequivocal identification. Quality control. General concluding remarks. Abbreviations. References. Drugs and Driving (R.A. Wennig, A. Verstraete). Introduction. Legal issues. Surveys that screened for several compounds. Surveys considering only one or two compounds. Case reports. Performance testing. Analytical toxicology. Analytical toxicology of methods specific for one or several drugs. Alternative matrices. Quality assurance. Pharmacology, pharmacokinetics, interpretation. Concluding remarks. References. Unconventional Samples and Alternative Matrices (P. Kintz, N. Samyn). Introduction. Saliva. Sweat. Meconium. Hair. General conclusion. List of abbreviations. References. Aspects of Quality Assurance in Forensic Toxicology (R.E. Aderjan). Introduction. A quality concept for analytical toxicological laboratories. Quality of the outcome. Conclusions. References. Doping Substances in Human and Animal Sport (J. Segura et al.). Introduction. Anabolic androgenic steroids. Stimulants. Diuretics. &bgr---Adrenergic drugs (rm&bgr---blockers and &bgr---agonists). Peptide hormones. Antiinflammatory drugs. Legal aspects. List of abbreviations. References. 'General Unknown' Analysis (R.A. de Zeeuw, J.P. Franke). Introduction. Key steps in STA. 3 Sample work-up. Differentiation and detection. Identification. Conclusions. References. Part II: Forensic Chemistry. Explosives (J. Yinon). Introduction. Extraction and clean-up procedures. Analytical methods. Concluding summary. References. The Chemical Analysis of Fire Debris for Potential Accelerants (W. Bertsch, Q. Ren). The nature of arson. The fire scene. Prospects and limitations of chemical analysis. Laboratory procedures. Current practices of forensic laboratories around the world. Conclusions and future developments. References. Writing Media and Documents (V.N. Aginsky). Paper chromatography and electrophoresis. Thin-layer chromatography. TLC and ink dating. Gas chromatography, gas chromatography-mass spectrometry. GC, GC-MS and ink dating. Pyrolysis gas chromatography. High performance liquid chromatography. Capillary electrophoresis. References. Part III: Forensic Identification of Individuals and Biological Traces. Forensic Identification of Individuals and Biological Traces - Forensic Genetics: From Classical Serological Genetic Markers to DNA Polymorphisms Analyzed by Microarray Technology (A. Carracedo, P. Sanchez-Diz). Introduction. Analysis of minisatellites using multi-locus and single-locus probes. PCR-based DNA systems: analysis of STRs. Standardization efforts and the value of the DNA evidence. References. Forensic Identification of Individuals and Biological Traces - Mitochondrial DNA in Forensic Genetics (M.V. Lareu, A. Salas). Introduction. Forensic applications. Mutation rate. Heteroplasmy. Homopolymeric tracts. Technical approach. Validation of mitochondrial DNA in forensic genetics and the statistical approach. Anthropological applications. References. Forensic Identification of Individuals and Biological Traces - The Human Y-Chromosome-- Male-specific Polymorphisms and Forensic Genetics (L. Gusmao et al.). Introduction. Inheritance properties of the Y-chromosome. Forensic application of Y-chromosome-specific markers. Y-chromosome-specific polymorphisms. Population genetics of Y-specific STRs. References.
• (source: Nielsen Book Data)9780444829986 20160528

The purpose of this volume is to present critical, up-to-date information on the separation methods and techniques applied in various disciplines of forensic science. The book cannot and should not replace a scientific paper in regard to the depth and coverage of a particular problem. It should, however, present the relevant problems in statu nascendi, showing their development, potential importance and future perspectives. The general structure of this volume corresponds to the most important forensic disciplines that apply various separation methods, i.e. forensic toxicology, chemistry and serohematology. The chapters devoted to forensic toxicology are focused on particular groups of illicit and therapeutic drugs and other substances of forensic interest. Also, some particular problems of forensic toxicology, such as drugs and driving, doping control, quality assurance, chiral separation, use of alternative matrices and general analytical strategy, are separately discussed. In the part devoted to forensic chemistry, the most important problems of the analysis of explosives, arson accelerants and writing media are individually covered. The part concerning forensic identification of individuals and biological traces presents all of the relevant separation techniques applied to endogenous macromolecules. The individual chapters have been written by scientists who not only carry out important scientific activity in their field, but are also known as very experienced forensic experts. Therefore, this volume gives not only the information about the application of separation methods in forensics, but also reflects the forensic community itself.
(source: Nielsen Book Data)9780444829986 20160528

• What Is an Expert Witness? So You Want to Be an Expert. The Attorney-expert Relationship. What Do You Offer the Attorney? Reports - To Be or Not to Be? How Much Are They Paying You for Your Testimony? Play Acting. Can You Determine Cause? Now the Deposition. The Courtroom, the Judge and the Jury. The Trial Comes Eventually. Nature of the Attack on You. The Aftermath.
• (source: Nielsen Book Data)9781560325314 20160527

As the world becomes more complex, a greater percentage of the present litigation is based upon very technical subjects. More and more chemicals are being introduced into our daily lives, without ever having been tested for possible side-effects. Consequently, product liability is increasing, and more and more often the toxicologist is being called into court to explain to judges and juries the concepts of technology and risk assessment. The Toxicologist As Expert Witness: A Hint Book for Courtroom Procedure is written with the toxicologist in mind who may not have the experience to testify at a time when toxicolgists as expert witnesses are in great demand.
(source: Nielsen Book Data)9781560325314 20160527
More and more litigation is now based upon technical evidence, but many toxicologists do not have the experience to testify effectively; nor indeed do all barristers know how to deal with scientists in the courtroom. This book provides guidance for.
(source: Nielsen Book Data)9781560325901 20160528