1. Smallpox and After: An Early History of the Treatment and Prevention of Infections
3. Lockjaw: Prevalent but Preventable
4. Pertussis Vaccine, Unfairly Maligned
At What Cost?
5. Vaccination: The Present and Future
6. The Conquest of Polio and the Contribution of Animal Experiments
7. Diphtheria: Understanding, Treatment and Prevention
II. Development of Life-saving Procedures
8. Development of Dialysis to Treat Loss of Kidney Function
9. The Contribution of Animal Experiments to Kidney Transplantation
10. Cardiopulmonary Bypass: Making Surgery on the Heart Possibe
11. Artificial Heart Valves: From Caged Ball to Bioprosthesis
12. Animals and Blood Transfusion
III. Drugs for Organic Diseases
13. Animal Experiments and the Production of Insulin
14. Animals and Humans: Remarkably Similar
15. Early Animal Experiments in Anaesthesia
16. The Control of Malignant Hypertension
17. Penicillin and Laboratory Animals: The Animal Rights Myth
18. The History of Thalidomide
19. Misleading Research or Misleading Statistics: Animal Experiments and Cancer Research
"Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives--both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine--from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer."--Publisher's website.
Dordrecht : Springer Science + Business Media, 1998.
Book — 1 online resource (160 pages)
This volume is the proceedings of the William Harvey Research Conference held in Cannes, France, on the 20th and 21st March, 1997. It describes the present knowledge of the structures of the cyclooxygenase isoforms and the experimental and clinical effects of selective inhibitors of cyclooxygenase-2. The pathophysiological significance of the cyclooxygenase enzymes in tumorigenesis, programmed cell death, vascular disease and asthma is also covered.