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• Contents: Introduction: The Art of the Speedbird, Oliver Green and Scott Anthony
• Taking to the Air: From Pioneers to Imperial, Oliver Green
• Conflict and a Changing World, Oliver Green
• Queen and Comet: Art and Aviation in the New Elizabethan Age, Scott Anthony
• Epilogue
• Notes
• Timeline
• Selected Further Reading
• Acknowledgements
• Image Credits
• Index.
• (source: Nielsen Book Data)

From Futurism and Modernism to Art Deco and Surrealism, aviation was from its earliest days inextricably linked with revolutionary new ways of seeing the world. Focusing on the golden age of British civil aviation, British Aviation Posters shows how art and design were applied with great creativity and style to develop and promote aviation in the UK and beyond. The story begins with the air shows and exhibitions of the early pioneers, through the start of regular passenger flights in the 1920s and the creation of Imperial Airways as the UK national carrier in 1924. By the 1930s passenger routes across the world were being developed and promoted with increasingly sophisticated visual publicity to persuade the British public to be more 'air minded' in a turbulent period of political and social upheaval. The New Elizabethan Age took UK aviation in new directions in the 1950s with BOAC and BEA ushering in the development of jet airliners and a growing consumer market that needed to be serviced by new forms of marketing and promotion. Drawing on British Airways' premier poster collection and featuring the work of such distinguished designers as Theyre Lee-Elliott, Ben Nicholson, Edward McKnight Kauffer, F.H.K. Henrion, Gabby Schreiber, Robin Day, Abram Games, Hugh Casson and Frank Wootton, British Aviation Posters offers a definitive account of this seminal period in modern UK design history as Oliver Green and Scott Anthony show how posters, publicity and graphic design were used to express the speed, progress and sheer excitement of flight.
(source: Nielsen Book Data)

• Acknowledgements List of illustrations
• 1. After the Great War: The origin of public relations
• 2. Beginnings: The Empire Marketing Board, 1926-33
• 3. The Projection of England and Documentary Cinema
• 4. A triumph of public relations: The GPO, 1933-35
• 5. The limits of public relations The BBC and The Ministry of Information
• 6. Rebuilding the nation: The Festival of Britain and the formation of the Institute of Public Relations
• 7. Conclusion Notes Appendix: The projection of England by Sir Stephen Tallents Bibliography Index.
• (source: Nielsen Book Data)

Public relations was established in Britain by a group of liberal intellectuals in the aftermath of the slump. Central to the startling story of Britain's early public relations pioneers is Sir Stephen Tallents, the inaugural President of the Institute of Public Relations. Tallents was a public sector entrepreneur who lent his patronage to John Grierson's documentary film movement, the BBC Overseas Service, the development of Listener Research and the staging of the Festival of Britain. A compelling portrait of how the social, economic and media revolutions of early twentieth century reshaped national life, Public relations and the making of modern Britain reveals a country struggling to cope with austerity and crisis that is at once very different from, and yet surprisingly similar to, our own. This book includes the first reprint of Tallents' influential 'The Projection of England' for over fifty years. It will interest students and scholars of media studies and modern British culture, history and politics.
(source: Nielsen Book Data)

• Acknowledgments Foreword Sir Christopher Frayling PART One: ARGUMENTS, IDEAS, ISSUES 1 John Grierson and the Lost World of the GPO Film Unit Jeffrey Richards 2 The GPO Film Unit and 'Britishness' in the 1930s Scott Anthony 3 GPO Films and Modern Design Yasuko Suga 4 Old Industry, New Science? The GPO Film Unit between Palaeotechnology and Neotechnology Timothy Boon 5 An Archivist's Perspective on the Work of the GPO Film Unit Steven Foxon PART TWO: FILM-MAKERS 6 Alberto Cavalcanti: Lessons in Fusion at the GPO Film Unit Charles Drazin 7 Harry Watt: on Land, at Sea and in the Air Amy Sargeant 8 Humphrey Jennings: The Customs of the Country Michael McCluskey 9 Portrait of an Invisible Man: The Working Life of Stewart McAllister, Film Editor Dai Vaughan 10 Job in a Million: Evelyn Spice at the GPO Barbara Evans 11 The Joy of Drooling: In Praise of Len Lye Kevin Jackson PART THREE: KEY DOCUMENTS FROM THE HISTORY OF THE GPO FILM UNIT PART FOUR: AESTHETICS 12 Rhythm, Modernity and the Politics of Sound
• James G. Mansell 13 Voiceover/Commentary Martin Stollery 14 National Identity, the GPO Film Unit and their Music E. Anna Claydon 15 Technology the GPO Film Unit Leo Enticknap 16 Modern art and Design in 1930s Britain: Contexts and Legacies of the Documentary Film Paul Rennie PART FIVE: THE GPO FILM UNIT AND TELECOMMUNICATIONS CULTURE PART SIX: FILMS 17 'Go the way the material calls you': Basil Wright and The Song of Ceylon Jon Hoare 18 The Horsey Mail: Documentary as Landscape David Matless 19 The GPO at Play: What's On Today and Spare Time Richard Haynes 20 The Silent Village: The GPO Film Unit Goes to War Wendy Webster 21 Visualising the World: The British Documentary at Unesco Zoe Druick 22 Counterpoints and Counterparts: Film at the Post-war GPO Patrick Russell PART SEVEN: THE GPO FILM UNTI AND THE MODERN POST OFFICE Postscript Roy Mayall Filmography Notes on Contributors Index.
• (source: Nielsen Book Data)

The General Post Office (GPO) Film Unit sat at the creative epicentre of Britain in the 1930s. It nurtured a vital crop of artistic talent, built a forum for a new kind of cinematic address and created Britain's first self-consciously national cinema. In 2011, UNESCO added its work to the UK Memory of the World Register, recognising its status as part of Britain's cultural heritage. Elements of the GPO Film Unit's story are well known: John Grierson's development of documentary cinema; the influence of Mass Observation and Surrealism on its cinematic vision; the Watt-Auden-Britten collaboration Night Mail. The Projection of Britain: A History of the GPO Film Unit brings together primary materials and critical appraisals to revisit, re-contextualise and revitalise these seminal moments in British cinema. Here, the insights of an archivist, a musicologist, a design historian, a sports historian, a geographer and a postman - among others - have been edited into a rich critical archaeology of a compelling moment in cinematic history. Interspersed with these essays are primary materials - memoirs, magazine articles, posters and government documents - that detail everything from Alberto Cavalcanti's vision for the documentary movement to a claim for the clothes Humphrey Jennings lost while shooting on location. In recent years there has been a resurgence of interest in the GPO Film Unit and its work, on the big screen, in DVD boxsets and on the web. The Projection of Britain ties together the Unit's diverse artistic, historical and cultural threads into an essential one-stop resource. Provocative, imaginative and ambitious, this expansive study is the definitive companion to an extraordinary episode in cinematic history.
(source: Nielsen Book Data)

While cancer immunotherapy targeting the adaptive immune system has led to prolonged disease-free survival in otherwise terminal patients, there are few effective cancer therapies targeting the innate immune system. However, there is mounting evidence that the cGAMP-STING innate immune pathway is a promising anticancer target. While cGAMP is synthesized and functions inside the cytoplasm, recent evidence has shown that cGAMP is exported by cancer cells and imported by cGAMP-sensing responder cells in the host, thereby acting as a paracrine immunotransmitter. This thesis focuses on three key open questions in the field of extracellular cGAMP signaling: First, which cells within tumors directly respond to endogenous extracellular cGAMP? Second, how does cGAMP enter these cells? And third, can we specifically enhance extracellular cGAMP in vivo by inhibiting its degradation? We found that M1-polarized macrophages, monocytes, NK cells, and CD4+ T cells comprise the initial cGAMP-sensing populations within tumors. Additionally, we identified the first known cGAMP importer, SLC19A1, as well as the dominant cGAMP importer in primary human monocytes, SLC46A2. Finally, we discovered and characterized ENPP1-H362A, a point mutation that selectively inhibits cGAMP degradation while permitting normal ATP hydrolysis. While Enpp1-H362A mice do not exhibit the systemic calcification seen in Enpp1-null mice, they are significantly more resistant to HSV-1 infection and are more sensitive to radiation-induced inflammation, suggesting that extracellular cGAMP plays a critical role in broad disease contexts. Although we are still in the early stages of understanding this pathway, the extracellular cGAMP signaling pathway is a new frontier in immunotherapy that has the potential to revolutionize the treatment of a wide range of human diseases