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1. Comparison of Landiolol and Digoxin as an Intravenous Drug for Controlling the Heart Rate in Patients with Atrial Fibrillation and Severely Depressed Left Ventricular Function [2020]

  • Hideki Koike, Katsuya Akitsu, Kensuke Yano, Masaya Shinohara, Ryou Wada, Tadashi Fujino, Takanori Ikeda, Takeya Suzuki, and Toshio Kinoshita
  • International Heart Journal. 2020, 61(5):944

2. The Difference in the Changes of Indoxyl Sulfate after Catheter Ablation among Atrial Fibrillation Patients with and without Kidney Dysfunction [2020]

  • Hideki Koike, Toshisuke Morita, Junko Tatebe, Ippei Watanabe, Masaya Shinohara, Toshio Kinoshita, Hitomi Yuzawa, Takeya Suzuki, Tadashi Fujino, and Takanori Ikeda
  • Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Subjects
Medicine and Science
Abstract
Abstract Indoxyl sulfate (IS), a protein-bound uremic toxin, induces chronic kidney disease (CKD) and atrial fibrillation (AF). Catheter ablation (CA) of AF improves the renal function. However, the transition of uremic toxins is unclear. This study aimed to investigate the transition of the serum IS level in AF patients with and without CKD after CA. A total of 138 consecutive AF patients who underwent CA and maintained sinus rhythm were prospectively enrolled (paroxysmal AF 67.4%). The patients were divided into 4 groups (non-CKD/low-IS:68, non-CKD/high-IS:28, CKD/low-IS:13, and CKD/high-IS:29). The plasma IS levels and estimated glomerular filtration rate (eGFR) were determined before and 1-year after CA. CKD was defined as CKD stage III and a high-IS according to the mean IS (IS ≥ 1.1 μg/ml). CA significantly improved the eGFR in CKD patients (p

3. Evaluation of oral anticoagulants in atrial fibrillation patients over 80 years of age with nonsevere frailty [2019]

  • Masaya Shinohara, Ryou Wada, Shintaro Yao, Kensuke Yano, Katsuya Akitsu, Hideki Koike, Toshio Kinoshita, Hitomi Yuzawa, Takeya Suzuki, Tadashi Fujino, and Takanori Ikeda
  • Journal of Arrhythmia, Vol 35, Iss 6, Pp 795-803 (2019)
Subjects
bleeding, direct oral anticoagulants, elderly, frail, warfarin, Diseases of the circulatory (Cardiovascular) system, and RC666-701
Abstract
Abstract Background The safety and efficacy of an oral anticoagulant (OAC) treatment and the difference between direct OACs (DOACs) and warfarin in nonsevere frail elderly patients with AF are unclear. Methods This was a retrospective and observational study of 354 patients over 80 years of age with nonsevere frailty who were diagnosed with AF and treated with OACs. Nonsevere frailty was defined as a clinical frailty scale score of

4. Comparison of the Transdermal Bisoprolol Patch with Oral Bisoprolol Fumarate Administration as a Therapeutic Agent for Idiopathic Frequent Premature Ventricular Contractions [2020]

  • Hideki Koike, Hitomi Yuzawa, Katsuya Akitsu, Kensuke Yano, Masaya Shinohara, Ryou Wada, Shintaro Yao, Tadashi Fujino, Takanori Ikeda, Takeya Suzuki, and Toshio Kinoshita
  • International Heart Journal. 2020, 61(3):510

5. Impact of Cancer on Bleeding and Ischemic Stroke in Atrial Fibrillation Patients Taking Rivaroxaban, a Direct Oral Anticoagulant [2019]

  • Katsuya Akitsu, Rine Nakanishi, Toshio Kinoshita, Hitomi Yuzawa, Tadashi Fujino, and Takanori Ikeda
  • Toho Journal of Medicine. 2019 5(2):40-46

6. Clinical Factors Associated with a Successful Catheter Ablation Outcome in Elderly Patients with Atrial Fibrillation [2020]

  • Hideki Koike, Hitomi Yuzawa, Katsuya Akitsu, Kensuke Yano, Masaya Shinohara, Midori Yamada, Shintaro Yao, Tadashi Fujino, Takanori Ikeda, Takeya Suzuki, and Toshio Kinoshita
  • International Heart Journal. 2020, 61(1):21

7. Assessment of drug-induced proarrhythmias due to pilsicainide in patients with atrial tachyarrhythmias [2016]

  • Hideki Koike, MD, Tadashi Fujino, MD, PhD, Makiko Koike, MD, Shintaro Yao, MD, Masaya Shinohara, MD, Ken Kitahara, MD, PhD, Toshio Kinoshita, MD, PhD, Hitomi Yuzawa, MD, Takeya Suzuki, MD, PhD, Hideyuki Sato, MD, Shunji Fukunaga, MD, Kenzaburo Kobayashi, MD, PhD, and Takanori Ikeda, MD, PhD, FJCC
  • Journal of Arrhythmia, Vol 32, Iss 6, Pp 468-473 (2016)
Subjects
Pilsicainide, Proarrhythmia, Renal dysfunction, QRS interval, QTc interval, Diseases of the circulatory (Cardiovascular) system, and RC666-701
Abstract
Background: Pilsicainide, a pure Na+ channel blocker, is a popular antiarrhythmic drug for the management of atrial tachyarrhythmias (AT), in Japan. However, serious drug-induced proarrhythmias (DIPs) may unexpectedly occur. We assessed the clinical background of AT patients presenting with DIPs caused by pilsicainide. Methods: This study retrospectively enrolled 874 consecutive patients (543 men, 63.6±15.3 years old, and 57.9±16.5 kg of body weight), who were orally administered pilsicainide for AT management. We evaluated the relationship between DIPs and serum pilsicainide concentration, renal dysfunction (estimate glomerular filtration rate, eGFR), and electrocardiogram (ECG) parameters. Results: Among the patients, 154 (17.6%) had renal dysfunction (eGFR

8. Weatherability of coated heat-treated wood [2019]

  • Akiyoshi ONOZAWA, Kei MAEDA, Madoka MURAI, Satoshi SHIDA, Toshio KINOSHITA, Yutaka KATAOKA, 信田 聡, 前田 啓, 小野澤 明良, 木下 稔夫, 村井 まどか, and 片岡 厚
  • 木材保存 / MOKUZAI HOZON (Wood Protection). 2019, 45(5):223

9. Right Ventricular Septal Pacing Using a Thin Lumenless Pacing Lead and Delivery System with a Deflectable Catheter Long-Term Outcomes [2018]

  • Hideki Koike, Hitomi Yuzawa, Masaya Shinohara, Tadashi Fujino, Takanori Ikeda, Takeya Suzuki, and Toshio Kinoshita
  • International Heart Journal. 2018, 59(6):1253

10. Development of the Molding Material Using Urushi Sap and Thinned Wood Powder [2017]

  • Toshio KINOSHITA and 木下 稔夫
  • 表面科学 / Hyomen Kagaku. 2017, 38(5):244

11. Surface analyses of coated heat-treated wood [2017]

  • Akiyoshi ONOZAWA, Madoka MURAI, Satoshi SHIDA, Toshio KINOSHITA, Yutaka KATAOKA, 信田 聡, 小野澤 明良, 木下 稔夫, 村井 まどか, and 片岡 厚
  • 木材保存 / MOKUZAI HOZON (Wood Protection). 2017, 43(5):250

12. Obesity Is Associated With the Development of Interstitial Pneumonia Under Long-Term Administration of Amiodarone in Refractory Atrial Fibrillation Patients [2016]

  • Hideki Koike, Hideyuki Sato, Hitomi Yuzawa, Ken Kitahara, Kenzaburo Kobayashi, Makiko Koike, Masaya Shinohara, Shunji Fukunaga, Tadashi Fujino, Takanori Ikeda, Takeya Suzuki, and Toshio Kinoshita
  • International Heart Journal. 2016, 57(1):30

13. Application of Fructooligosaccharide to a Hemodialysis Patient - Focused on the Change of Intestinal Bacterial Flora - [1996]

  • Yuichiro TAKAHASHI, Kazuomi KADOWAKI, Yasuhito TASHIRO, Toshio TAKIZAWA, and Toshio KINOSHITA
  • Bifidus. 1996 9(2):141-150

14. Evaluation of High Performance Liquid Chromatography for Determination of Methotrexate in Human Serum ―Comparison with Fluorescence Polarization Immunoassay and Application for Osteosarcoma Patients― [1994]

  • RYOICHI MINAGAWA, YUKIKO WATANABE, DENJIRO KAJI, YASUAKI AOKI, HIROAKI KUBO, and TOSHIO KINOSHITA
  • Japanese Journal of Hospital Pharmacy. 1994 20(5):375-379

15. Stabilization of Ascorbic Acid and Its Quantitative Analysis in Drug Preparations by High-Performance Liquid Chromatography [1993]

  • SHUJI YAMAUCHI, NORIYUKI NIMURA, TOSHIO KINOSHITA, and TOSHIHIKO HANAI
  • Journal of Pharmaceutical Science and Technology, Japan. 1993 53(3):169-175

16. Dyeing for 3D parts made using Additive Manufacturing technologies by Powder Bed Fusion [2014]

  • Akiyoshi Onozawa, Madoka Murai, Toshio Kinoshita, Yoshimi Kamiya, Yuki Yamauchi, 小野澤 明良, 山内 友貴, 木下 稔夫, 村井 まどか, and 神谷 嘉美
  • Proceedings of JSPE Semestrial Meeting. 2014, :313

17. The mechanisms underlying fibroblast apoptosis regulated by growth factors during wound healing [2010]

  • Yoshikiyo, Akasaka, Ichiro, Ono, Takafumi, Kamiya, Yukio, Ishikawa, Toshio, Kinoshita, Shigeki, Ishiguro, Tomoko, Yokoo, Risa, Imaizumi, Naomi, Inomata, Kazuko, Fujita, Yuri, Akishima-Fukasawa, Miwa, Uzuki, Kinji, Ito, and Toshiharu, Ishii
  • The Journal of Pathology. Jul 01, 2010 221(3):285-299

18. 15. A molecular control structure of the hypertensive heart failure cardiac muscle remodeling with cytokine [2012]

  • Toshio Kinoshita and Kennya Suzuki
  • Journal of the Medical Society of Toho University. 2012 59(4):201-201

19. 7. A molecular control structure of the hypertensive heart failure cardiac muscle remodeling with cytokine [2012]

  • Toshio Kinoshita and Junichi Yamazaki
  • Journal of the Medical Society of Toho University. 2012 59(4):192-192

20. Analysis Services on Surface Finishing in Tokyo Metropolitan Industrial Technology Research Institute [2013]

  • Atsushi MITSUO, Hiroshi UENO, Toshio KINOSHITA, 三尾 淳, 上野 博志, and 木下 稔夫
  • 表面技術 / Journal of The Surface Finishing Society of Japan. 2013, 64(9):489

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