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Nilsson, Johanna, Constantinescu, Julius, Nellgård, Bengt, Jakobsson, Protik, Brum, Wagner S., Gobom, Johan, Forsgren, Lars, Dalla, Keti, Constantinescu, Radu, Zetterberg, Henrik, Hansson, Oskar, Blennow, Kaj, Bäckström, David C, M.D., and Brinkmalm, Ann
- Movement Disorders. 38(2):267-277
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Medical and Health Sciences, Clinical Medicine, Neurology, Medicin och hälsovetenskap, Klinisk medicin, Neurologi, Basic Medicine, Neurosciences, Medicinska och farmaceutiska grundvetenskaper, Neurovetenskaper, biomarkers, multiple system atrophy, Parkinson's disease, progressive supranuclear palsy, and synaptic dysfunction
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Background: Synaptic dysfunction and degeneration are central contributors to the pathogenesis and progression of parkinsonian disorders. Therefore, identification and validation of biomarkers reflecting pathological synaptic alterations are greatly needed and could be used in prognostic assessment and to monitor treatment effects.Objective: To explore candidate biomarkers of synaptic dysfunction in Parkinson's disease (PD) and related disorders.Methods: Mass spectrometry was used to quantify 15 synaptic proteins in two clinical cerebrospinal fluid (CSF) cohorts, including PD (n1 = 51, n2 = 101), corticobasal degeneration (CBD) (n1 = 11, n2 = 3), progressive supranuclear palsy (PSP) (n1 = 22, n2 = 21), multiple system atrophy (MSA) (n1 = 31, n2 = 26), and healthy control (HC) (n1 = 48, n2 = 30) participants, as well as Alzheimer's disease (AD) (n2 = 23) patients in the second cohort.Results: Across both cohorts, lower levels of the neuronal pentraxins (NPTX; 1, 2, and receptor) were found in PD, MSA, and PSP, compared with HC. In MSA and PSP, lower neurogranin, AP2B1, and complexin-2 levels compared with HC were observed. In AD, levels of 14-3-3 zeta/delta, beta- and gamma-synuclein were higher compared with the parkinsonian disorders. Lower pentraxin levels in PD correlated with Mini-Mental State Exam scores and specific cognitive deficits (NPTX2; rho = 0.25–0.32, P < 0.05) and reduced dopaminergic pre-synaptic integrity as measured by DaTSCAN (NPTX2; rho = 0.29, P = 0.023). Additionally, lower levels were associated with the progression of postural imbalance and gait difficulty symptoms (All NPTX; β-estimate = −0.025 to −0.038, P < 0.05) and cognitive decline (NPTX2; β-estimate = 0.32, P = 0.021).Conclusions: These novel findings show different alterations of synaptic proteins in parkinsonian disorders compared with AD and HC. The neuronal pentraxins may serve as prognostic CSF biomarkers for both cognitive and motor symptom progression in PD.
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Schwech, Nurda, Nilsson, Johanna, and Gabre, Pia
- Clinical and Experimental Dental Research. 9(1):55-65
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Medical and Health Sciences, Clinical Medicine, Dentistry, Medicin och hälsovetenskap, Klinisk medicin, Odontologi, medication-related osteonecrosis, risk factors, tooth extractions, Oral and Maxillofacial Surgery, and Käkkirurgi
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Objectives: Antiresorptive medication has been reported to be associated with medication-related osteonecrosis of the jaw (MRONJ). This systematic review aims at investigating the incidence of and risk factors for MRONJ after tooth extractions in cancer patients treated with high-dose bisphosphonate and denosumab (BP and DS). Material and methods: The protocol followed the PRISMA statement list and was registered in PROSPERO. Searches were performed for literature published up to April 2021 in the electronic databases PubMed, Embase, Web of Science and CINAHL, and then supplemented by manual research.Results: The search process resulted in 771 identified articles, of which seven studies fitted the population, intervention, comparison, and outcome (PICO) framework. All were observational studies and four had control groups. A total of 550 patients treated with BP and DS were identified of whom 271 had received tooth extractions after medication onset. Due to significant heterogenicity in the collected data only a qualitative analysis was performed. The MRONJ incidence after tooth extractions varied between 11 and 50% at patient level. MRONJ occurred up to three years after the tooth extraction. Teeth affected by inflammation before the extraction and additional osteotomy during the surgical procedure were identified as risk factors. Conclusion: Reliable methods of diagnosing MRONJ and adequate follow-up period are important factors in obtaining the actual incidence of MRONJ after tooth extractions in patients treated with high-dose BP and DS.
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Nilsson, Johanna, Cousins, K. A. Q., Gobom, Johan, Portelius, E., Chen-Plotkin, A., Shaw, L. M., Grossman, M., Irwin, D. J., Trojanowski, J. Q., Zetterberg, Henrik, Blennow, Kaj, Brinkmalm, Ann, Göteborgs universitet, Sahlgrenska akademin, Institutionen för neurovetenskap och fysiologi, and Gothenburg University, Sahlgrenska Academy, Institute of Neuroscience and Physiology
- Alzheimers & Dementia. 19(5):1775-1784
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Neurovetenskaper, Neurosciences, Alzheimer's disease, biomarkers, frontotemporal lobar degeneration, Lewy, body spectrum of disorders, synaptic pathology, mass spectrometry, diagnosis, correlate, proteins, decline, alpha, and Neurosciences & Neurology
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Introduction Synaptic degeneration is a key part of the pathophysiology of neurodegenerative diseases, and biomarkers reflecting the pathological alterations are greatly needed. Method Seventeen synaptic proteins were quantified in a pathology-confirmed cerebrospinal fluid cohort of patients with Alzheimer's disease (AD; n = 63), frontotemporal lobar degeneration (FTLD; n = 53), and Lewy body spectrum of disorders (LBD; n = 21), as well as healthy controls (HC; n = 48). Results Comparisons revealed four distinct patterns: markers decreased across all neurodegenerative conditions compared to HC (the neuronal pentraxins), markers increased across all neurodegenerative conditions (14-3-3 zeta/delta), markers selectively increased in AD compared to other neurodegenerative conditions (neurogranin and beta-synuclein), and markers selectively decreased in LBD and FTLD compared to HC and AD (AP2B1 and syntaxin-1B). Discussion Several of the synaptic proteins may serve as biomarkers for synaptic dysfunction in AD, LBD, and FTLD. Additionally, differential patterns of synaptic protein alterations seem to be present across neurodegenerative diseases. Highlights A panel of synaptic proteins were quantified in the cerebrospinal fluid using mass spectrometry. We compared Alzheimer's disease, frontotemporal degeneration, and Lewy body spectrum of disorders. Pathology was confirmed by autopsy or familial mutations. We discovered synaptic biomarkers for synaptic degeneration and cognitive decline. We found differential patterns of synaptic proteins across neurodegenerative diseases.
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Nilsson, Johanna, Constantinescu, Julius, Nellgård, Bengt, Jakobsson, Protik, Brum, Wagner S., Gobom, Johan, Forsgren, Lars, Dalla, Keti, Constantinescu, Radu, Zetterberg, Henrik, Hansson, Oskar, Blennow, Kaj, Bäckström, David, and Brinkmalm, Ann
- Movement Disorders MultiPark: Multidisciplinary research focused on Parkinson´s disease.
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biomarkers, multiple system atrophy, Parkinson's disease, progressive supranuclear palsy, synaptic dysfunction, Medicin och hälsovetenskap, Klinisk medicin, Neurologi, Medical and Health Sciences, Clinical Medicine, and Neurology
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Background: Synaptic dysfunction and degeneration are central contributors to the pathogenesis and progression of parkinsonian disorders. Therefore, identification and validation of biomarkers reflecting pathological synaptic alterations are greatly needed and could be used in prognostic assessment and to monitor treatment effects. Objective: To explore candidate biomarkers of synaptic dysfunction in Parkinson's disease (PD) and related disorders. Methods: Mass spectrometry was used to quantify 15 synaptic proteins in two clinical cerebrospinal fluid (CSF) cohorts, including PD (n1 = 51, n2 = 101), corticobasal degeneration (CBD) (n1 = 11, n2 = 3), progressive supranuclear palsy (PSP) (n1 = 22, n2 = 21), multiple system atrophy (MSA) (n1 = 31, n2 = 26), and healthy control (HC) (n1 = 48, n2 = 30) participants, as well as Alzheimer's disease (AD) (n2 = 23) patients in the second cohort. Results: Across both cohorts, lower levels of the neuronal pentraxins (NPTX; 1, 2, and receptor) were found in PD, MSA, and PSP, compared with HC. In MSA and PSP, lower neurogranin, AP2B1, and complexin-2 levels compared with HC were observed. In AD, levels of 14-3-3 zeta/delta, beta- and gamma-synuclein were higher compared with the parkinsonian disorders. Lower pentraxin levels in PD correlated with Mini-Mental State Exam scores and specific cognitive deficits (NPTX2; rho = 0.25–0.32, P < 0.05) and reduced dopaminergic pre-synaptic integrity as measured by DaTSCAN (NPTX2; rho = 0.29, P = 0.023). Additionally, lower levels were associated with the progression of postural imbalance and gait difficulty symptoms (All NPTX; β-estimate = −0.025 to −0.038, P < 0.05) and cognitive decline (NPTX2; β-estimate = 0.32, P = 0.021). Conclusions: These novel findings show different alterations of synaptic proteins in parkinsonian disorders compared with AD and HC. The neuronal pentraxins may serve as prognostic CSF biomarkers for both cognitive and motor symptom progression in PD.
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Saloner, Rowan, Fonseca, Corrina, Paolillo, Emily W, Asken, Breton M, Djukic, Nina A, Lee, Shannon, Nilsson, Johanna, Brinkmalm, Ann, Blennow, Kaj, Zetterberg, Henrik, Kramer, Joel H, and Casaletto, Kaitlin B
- Neurology. 99(20)
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Dementia, Alzheimer's Disease, Aging, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, Neurosciences, Brain Disorders, Acquired Cognitive Impairment, Neurological, Clinical Sciences, Cognitive Sciences, and Neurology & Neurosurgery
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Background and objectivesSynaptic dysfunction and degeneration is a predominant feature of brain aging and synaptic preservation buffers against Alzheimer's disease (AD) protein-related brain atrophy. We tested whether cerebrospinal fluid (CSF) synaptic protein concentrations similarly moderate the effects of axonal injury, indexed via CSF neurofilament light [NfL], on brain atrophy in clinically normal adults.MethodsClinically normal older adults enrolled in the observational Hillblom Aging Network study at the UCSF Memory and Aging Center completed baseline lumbar puncture and longitudinal brain MRI (Mean scan [follow-up]=2.6 [3.7 years]). CSF was assayed for synaptic proteins (synaptotagmin-1, synaptosomal-associated protein 2 [SNAP-25], neurogranin, growth associated protein 43 [GAP-43]), axonal injury (NfL), and core AD biomarkers (ptau181/Aβ42 ratio; reflecting AD proteinopathy). Ten bilateral temporo-parietal gray matter ROIs shown to be sensitive to clinical AD were summed to generate a composite temporo-parietal ROI. Linear mixed-effects models tested statistical moderation of baseline synaptic proteins on baseline NfL-related temporo-parietal trajectories, controlling for ptau181/Aβ42 ratios.ResultsForty-six clinically normal older adults (Mean age=70; 43% female) were included. Synaptic proteins exhibited small to medium correlations with NfL (r range: .10 to .36). Higher baseline NfL, but not ptau181/Aβ42 ratios, predicted steeper temporo-parietal atrophy (NfL x time: β=-0.08, p
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Nilsson, Johanna, Gobom, Johan, Sjödin, Simon, Brinkmalm, Gunnar, Ashton, Nicholas J, Svensson, Johan, Johansson, Per, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, and Brinkmalm, Ann
- Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 13(1)
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Alzheimer, Synaptic dysfunction, CSF BIOMARKERS, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Neurovetenskaper, Medical and Health Sciences, Basic Medicine, and Neurosciences
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Introduction: Synaptic dysfunction and degeneration is one of the earliest events in Alzheimer's disease (AD) and the best correlate of cognitive decline. Thus, identification and validation of biomarkers reflecting synaptic degeneration to be used as prognostic biomarkers are greatly needed.Method: Solid-phase extraction and parallel reaction monitoring mass spectrometry were used to quantify 17 synaptic proteins in CSF, in two cross-sectional studies including AD (n = 52) and controls (n = 37).Results: Increased concentrations of beta-synuclein, gamma-synuclein, neurogranin, phosphatidylethanolamine-binding protein 1, and 14-3-3 proteins were observed in AD patients compared to controls, while neuronal pentraxin-2 and neuronal pentraxin receptor were decreased.Discussion: We have established a method with a novel panel of synaptic proteins as biomarkers of synaptic dysfunction. The results indicate that several of the proteins included in the panel may serve as synaptic biomarkers for AD.
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Barazanji, Danah, Khalid, Anum, and Nilsson, Johanna E
- Handbook of Research on Solutions for Equity and Social Justice in Education. 2023, p107-122.
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The Development of the Teacher Social Justice Advocacy for Children Scale ABSTRACT INTRODUCTION Social injustices can occur in many forms, such as racism, oppression, transphobia, and poverty resulting in negative [...]
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Gracias, Jessica, Orhan, Funda, Hörbeck, Elin, Holmén-Larsson, Jessica, Khanlarkani, Neda, Malwade, Susmita, Goparaju, Sravan K., Schwieler, Lilly, Demirel, İlknur Ş., Fu, Ting, Fatourus-Bergman, Helena, Pelanis, Aurimantas, Goold, Carleton P., Goulding, Anneli, Annerbrink, Kristina, Isgren, Anniella, Sparding, Timea, Schalling, Martin, Yañez, Viviana A. Carcamo, Göpfert, Jens C., Nilsson, Johanna, Brinkmalm, Ann, Blennow, Kaj, Zetterberg, Henrik, Engberg, Göran, Piehl, Fredrik, Sheridan, Steven D., Perlis, Roy H., Cervenka, Simon, Erhardt, Sophie, Landen, Mikael, and Sellgren, Carl M.
- Nature Communications. 13(1)
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Sogorb-Esteve, Aitana, Nilsson, Johanna, Swift, Imogen J., Heller, Carolin, Bocchetta, Martina, Russell, Lucy L., Peakman, Georgia, Convery, Rhian S., van Swieten, John C., Seelaar, Harro, Borroni, Barbara, Galimberti, Daniela, Sanchez-Valle, Raquel, Laforce, Jr., Robert, Moreno, Fermin, Synofzik, Matthis, Graff, Caroline, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Vandenberghe, Rik, Finger, Elizabeth, Tagliavini, Fabrizio, Santana, Isabel, Butler, Chris R., Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Otto, Markus, Sorbi, Sandro, Le Ber, Isabelle, Pasquier, Florence, Gobom, Johan, Brinkmalm, Ann, Blennow, Kaj, Zetterberg, Henrik, and Rohrer, Jonathan D.
- Alzheimer's Research & Therapy. 14(1)
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Nilsson, Johanna, Ashton, Nicholas J., Benedet, Andrea L., Montoliu-Gaya, Laia, Gobom, Johan, Pascoal, Tharick A., Chamoun, Mira, Portelius, Erik, Jeromin, Andreas, Mendes, Muriel, Zetterberg, Henrik, Rosa-Neto, Pedro, Brinkmalm, Ann, and Blennow, Kaj
- Alzheimer's Research & Therapy. 14(1)
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Lygnerud, Kristina, Klugman, Sofia, Fransson, Nathalie, and Nilsson, Johanna
- In
Energy January 2022
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Camporesi, Elena, Nilsson, Johanna, Vrillon, Agathe, Cognat, Emmanuel, Hourregue, Claire, Zetterberg, Henrik, Blennow, Kaj, Becker, Bruno, Brinkmalm, Ann, Paquet, Claire, and Brinkmalm, Gunnar
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eBioMedicine January 2022 75
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Hildingsson, Ingegerd, Nilsson, Johanna, Merio, Elida, and Larsson, Birgitta
- European Journal of Midwifery. 5(August):1-9
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Medical and Health Sciences, Clinical Medicine, Obstetrics, Gynecology and Reproductive Medicine, Medicin och hälsovetenskap, Klinisk medicin, Reproduktionsmedicin och gynekologi, anxiety, depression, fear of birth, pregnancy, prenatal attachment, and women
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INTRODUCTION Anxiety and depression during pregnancy could imply difficulties in the attachment to the unborn baby. The objective of this study was to investigate the prevalence and change in anxiety and depressive symptoms in pregnant women with fear of birth. Another aim was to explore associations between symptoms of anxiety and depression on prenatal attachment. METHODS This is a longitudinal cohort study of 77 pregnant women with fear of birth in three hospitals in Sweden. Data were collected by three questionnaires in mid and late pregnancy and two months after birth. RESULTS Anxiety symptoms were more often reported than depressive symptoms, significantly decreasing over time in both conditions. Anxiety symptoms were associated with low education level, negative feelings towards the upcoming birth, and levels of fear of birth. Depressive symptoms were associated with levels of fear of birth. One in five women presented with fear of birth, anxiety, and depressive symptoms, suggesting that co-morbidity was quite common in this sample. Depressive symptoms and co-morbidity were negatively associated with prenatal attachment. CONCLUSIONS This study shows that symptoms of anxiety and depression in women with fear of birth vary over time and that co-morbidity is quite common. Lack of emotional well-being was related to prenatal attachment. Healthcare professionals must identify and support women with anxiety and depressive symptoms and fear of birth so that difficulties in the relationship between the mother and the newborn baby might be reduced.
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Nilsson, Johanna, Nysjö, Fredrik, Nyström, Ingela, Kämpe, Johan, and Thor, Andreas
- International Journal of Computer Assisted Radiology and Surgery. 16(6):1059-1068
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Engineering and Technology, Medical Engineering, Medical Image Processing, Teknik och teknologier, Medicinteknik, Medicinsk bildbehandling, Medical and Health Sciences, Clinical Medicine, Surgery, Medicin och hälsovetenskap, Klinisk medicin, Kirurgi, Virtual surgical planning, Haptic technology, Complex mandible fractures., Computerized Image Processing, and Datoriserad bildbehandling
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The management of complex mandible fractures, i.e severely comminuted or fractures of edentulous/atrophic mandibles, can be challenging. This is due to the three-dimensional loss of bone, which limits the possibility for accurate anatomic reduction. Virtual surgery planning (VSP) can provide improved accuracy and shorter operating times, but is often not employed for trauma cases because of time constraints and complex user interfaces limited to two-dimensional interaction with three-dimensional data. In this study, we evaluate the accuracy, precision, and time efficiency of the Haptic Assisted Surgery Planning system (HASP), an in-house VSP system that supports stereo graphics, six degrees-of-freedom input and haptics, to improve the surgical planning. Three operators performed planning in HASP on Computed Tomography (CT) and Come Beam Computed Tomography (CBCT) images of a plastic skull model and on twelve retrospective cases with complex mandible fractures. The result shows an accuracy and reproducibility of less than 2mm when using HASP, with an average planning time of 15 minutes, including time for segmentation in the software BoneSplit. This study presents an in-house haptic assisted planning tool for cranio-maxillofacial surgery with high usability that can be used for preoperative planning and evaluation of complex mandible fractures.
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Wörner, Tobias, Nilsson, Johanna, Thorborg, Kristian, Granlund, Viktor, Stålman, Anders, and Eek, Frida
- Orthopaedic Journal of Sports Medicine. 7(6)
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femoroacetabular impingement, hip arthroscopic surgery, physical therapy, rehabilitation, athletic performance, muscle strength, range of motion, Medicin och hälsovetenskap, Klinisk medicin, Ortopedi, Medical and Health Sciences, Clinical Medicine, Orthopedics, Hälsovetenskap, Sjukgymnastik, Health Sciences, and Physiotherapy
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Background:Little is known about hip-related function, mobility, and performance in patients after hip arthroscopic surgery (HA) during the time that return to sports can be expected.Purpose:To evaluate measures of subjective and objective hip function 6 to 10 months after HA in patients compared with healthy controls and to compare objective function in the HA group between the operated and nonoperated hips.Study Design:Cross-sectional study; Level of evidence, 3.Methods:A total of 33 patients who had undergone HA (mean, 8.1 ± 2.6 months postoperatively) and 33 healthy participants matched on sex, age, and activity level were compared regarding subjective hip function (Copenhagen Hip and Groin Outcome Score [HAGOS]) and objective function including hip range of motion (ROM; flexion, internal rotation, and external rotation), isometric hip muscle strength (adduction, abduction, flexion, internal rotation, and external rotation), and performance-based measures: the Y Balance Test (YBT), medial and lateral triple-hop test, and Illinois agility test. Group differences were analyzed using independent-samples t tests. Paired-samples t tests were used for a comparison of the operated and nonoperated hips. Standard effect sizes (Cohen d) were provided for all outcomes.Results:The HA group reported worse subjective hip function than the control group (HAGOS subscores: d = –0.7 to –2.1; P ≤ .004). Objective measures of hip ROM (d = –0.5 to –1.1; P ≤ .048), hip flexion strength (d = –0.5; P = .043), and posteromedial reach of the YBT (d = –0.5; P = .043) were also reduced in the HA group, although there were no significant differences between groups regarding the remaining objective measures (d = –0.1 to –0.4; P ≥ .102 to .534). The only significant difference between the operated and nonoperated hips in the HA group was reduced passive hip flexion (d = –0.4; P = .045).Conclusion:Patients who had undergone HA demonstrated reduced subjective hip function compared with controls 6 to 10 months after surgery, when return to sports can be expected. While most objective strength and performance test results were comparable between the HA and control groups at 6 to 10 months after surgery, the HA group presented with impairments related to hip mobility and hip flexion strength. No consistent pattern of impairments was found in operated hips compared with nonoperated hips.
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Nilsson, Johanna, Nilsson, Filippa, and Johansson, Ellen
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Influencer marketing, Social media marketing, Electronic Word-of-Mouth, Consumer behavior, Purchase intention, TikTok marketing., Business Administration, and Företagsekonomi
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This study investigates the impact of trustworthiness, perceived expertise, and parasocial relationships on Swedish consumers' purchase intentions on TikTok, focusing on influencer marketing. The problem addressed in this study is the lack of understanding of consumer behavior on TikTok in the context of influencer marketing. While TikTok has become a popular platform for influencer marketing due to its high engagement rates and entertaining marketing concept, limited research exists on the factors that influence consumer purchase intentions on the platform. The study aims to understand the factors that influence consumer behavior on TikTok and its impact on purchase intentions, using the theory of persuasion. The method used in this research is a quantitative study where the authors used a survey method to collect primary data from 138 Swedish consumers. STATA was used to analyze the data, and the findings reveal that the trustworthiness and parasocial relationships of influencers significantly impact purchase intentions, while perceived expertise has no significant impact on the platform TikTok. This study's results can guide marketing professionals and influencers to develop effective influencer marketing strategies on TikTok, which offers immense marketing opportunities for brands seeking to reach younger audiences with high engagement rates.
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Nilsson, Johanna and Svensson, Johanna
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Angina pectoris, caring, experience, nursing, patient perspective, omvårdnad, patientperspektiv, upplevelse, Nursing, and Omvårdnad
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Bakgrund: Angina pectoris ingår i folksjukdomen hjärt- och kärlsjukdomarvilka i hög grad är relaterade till livsstilsfaktorer. Aterosklerosprocessen ären vanlig bakomliggande orsak. Angina pectoris orsakar patienten stortlidande samt stora kostnader för samhället. Vid personcentrerad vårdengagerar och aktiverar sjuksköterskan patienten i omvårdnaden. Syfte:Syftet var att belysa omvårdnad vid angina pectoris ur ett patientperspektiv.Metod: Metoden var en allmän litteraturstudie där nio artiklar ingick.Databearbetning utfördes enligt Popenoes vägledning för litteraturstudiervilket resulterade i att tre kategorier skapades. Resultat: Databearbetningenresulterade i tre rubriker: upplevelse av omvårdnad som förmedlar trygghet,upplevelse av att ha en kommunikation med sjuksköterska samt upplevelseav att få information. I resultatet framgick att patienter upplevde stort behovav en omvårdnad som förmedlar trygghet och information. Kommunikationansågs vara en viktig komponent i relationen med sjuksköterskan.Konklusion: I omvårdnaden av angina pectoris värdesatte patientertrygghet, information samt en god kommunikation med sjuksköterskan.Därför är det viktigt för sjuksköterskan med aktuell kunskap om anginapectoris och dess omvårdnad samt personcentrerad vård. Nyckelord:Angina pectoris, omvårdnad, patientperspektiv, upplevelse.
Background: Angina pectoris is a cardiovascular disease. Cardiovasculardiseases are public health diseases, largely related to lifestyle factors. Theatherosclerosis process is a common underlying cause. Angina pectoriscauses great suffering for the patient and great costs for the society. Inperson-centered care, the nurse engages and activates the patient in the care.Aim: The aim was to enlighten nursing for angina pectoris from a patientperspective. Method: The method was a general literature study whichincluded nine article. The data processing was carried out according toPoponoe’s guidance, which created three categories. Results: The dataprocessing resulted in three different categories: experience of nursing thatconveys security, experience of communication with a nurse and experienceof receiving information. The results showed that patients experienced agreat need for care that conveys security and information. Communicationwas considered an important component in the relationship with the nurse.Conclusion: In the care of angina pectoris, patients valued security,information and good communication with the nurse. Therefore, it isimportant for the nurse to have current knowledge of angina pectoris and itscare, as well as person centered care. Keywords: Angina pectoris, nursing,patient perspective, experience
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Nilsson, Johanna and Hellichius Georgsson, Emily
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Journalism, Threat, Hatred, Harassment, Sweden, Discourse theory, Interview, Media and Communications, and Medie- och kommunikationsvetenskap
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This study examines how local journalists in Sweden view, understand and manage threats, hatred and harassment in their professional role. The study is based on qualitative interviews with eight journalists, four men and four women, from different local newspapers in Sweden. The interviews are analyzed through a theoretical framework inspired by discourse theory. The purpose of this study is to examine how journalists are affected by threats, hatred and harassment. All material has been collected throughout the study and is used to understand how journalists being victims of hatred, threats and harassment affects their duty to society as being a democratic vessel for the public opinion. The research questions for the study are: 1. How do journalists experience safety risks in their professional practice? 2. How do journalists weigh the risk of being exposed to hatred, threats and harassment as opposed to reporting about subjects they are interested in and find important? 3. Do journalists experience institutional support and how safe does the support make them feel? Theories such as the media's democratic role in society and the journalistic standard of practice are used to answer the research questions and analyze the material. The result of the study shows that hatred, threats and harassment is an established part of journalistic practice that is known throughout institutions and by journalists themselves. Furthermore the result shows a lack of institutionalized support. Neither their previous education discussed how they’re supposed to handle hatred, threats and harassments nor does their current workplace discuss it. In line with previous research, the informants believed that hatred, threats and harassment take different forms depending on the gender of the journalist and that women are more vulnerable, which they claimed were because of the patriarchal structures of our society. The result shows that the informants use avoidance strategies when it comes to reducing the risk of exposure. Subconsciously, they may have reframed, changed the narrative or censored themselves – but in such cases without their direct knowledge.
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19. Drömmen om Europa 2027 : En kvalitativ studie om fotbollsklubben IK Sirius och dess supportrar [2023]
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Pettersson, Ida and Nilsson, Johanna
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Eldsjäl, kommersialisering, supporterskap, Social Work, and Socialt arbete
- Abstract
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IK Sirius är en fotbollsklubb från Uppsala som de senaste åren har etablerat sig i den högsta serien i Sverige, Allsvenskan. I takt med att fotbollsklubben har utvecklats har även antalet supportrar som går på lagets matcher ökat markant samt antalet medlemmar i supporterföreningen Västra Sidan. För att lyckas etablera sig och även kunna utvecklas ännu mer har Sirius valt att lägga den kommersiella delen av verksamheten i ett aktiebolag, detta för att stärka klubbens ekonomi ytterligare. Klubben har genom detta blivit mer kommersiell och professionell och denna uppsats syftar till att undersöka hur supporterskapet har förändrats till följd av detta. Vidare kommer uppsatsen att undersöka om betydelsen av eldsjälar förändras i den moderna fotbollen. Det finns tidigare forskning om hur fotbollen påverkar supportrarnas beteende, men inte så mycket forskning om hur supportrar påverkar fotbollen eller fotbollsklubbar vilket denna studie vill bidra med. Empiri har samlats in genom tio semistrukturerade intervjuer där respondenterna är en blandning av supportrar från supporterföreningen Västra Sidan, en oberoende journalist samt en person som arbetar inom IK Sirius. Datan har sedan analyserat genom en kvalitativ konventionell innehållsanalys. För att tolka förändringen av supporterskapet har Nyinstitutionell teori, Samproduktion samt Interactional Ritual Theory använts för att belysa både den organisatoriska samt sociala förändringen som har skett. Studien visar att det framförallt är gemenskapen som får eldsjälar i form av supportrar att engagera sig och lägga både mycket tid och pengar på sitt supporterskap. Resultatet visar även att fotbollsklubbar i hög grad är beroende av eldsjälar i form av ideellt arbete men framförallt genom biljettintäkter som är en av klubbens största inkomstkällor. Fotbollsklubbar anses idag vara en produkt på en marknad och supportrarna skapar ett mervärde genom att de bidrar med bra stämning på läktaren vilket i sin tur lockar fler personer att gå på matcherna.
- Full text Direct access may be available at NDLTD
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Christensen, Sanne and Nilsson, Johanna
- Subjects
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Government, homeless, ideal organizations, non-profit, public sector, voluntary organizations, Social Work, and Socialt arbete
- Abstract
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The responsibility of the homeless has for a long time been a gray area. Voluntary organizations were founded because no one else was helping the homeless. Today the responsibility to take care of the homeless lies with the public sector and the respective municipalities. So why is it that new voluntary organizations keep appearing? The purpose of the study is to find out what role voluntary organizations play in the work against homelessness and whether they have an impact on the social work of today. Analysis of the results was done with theories of street-level bureaucrats and social citizenship. The results of this study show how much responsibility voluntary organizations take in the work against homelessness. A responsibility that many of the interviewees know should lie with the public sector instead. The voluntary organizations fulfills the participants' basic needs and provides them a sense of security. The results draw attention to the fact that the work that the voluntary organizations do is often taken for granted.
- Full text Direct access may be available at NDLTD
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