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1. Rationalization design, soluble expression and PEG modification of highly active recombinant human-porcine uricase mutant protein.

2. Characteristic fingerprint spectrum of α-synuclein mutants on terahertz time-domain spectroscopy.

3. Mutant huntingtin protein induces MLH1 degradation, DNA hyperexcision, and cGAS-STING-dependent apoptosis.

4. Functional properties of measles virus proteins derived from a subacute sclerosing panencephalitis patient who received repeated remdesivir treatments.

5. OmeDDG: Improved Protein Mutation Stability Prediction Based on Predicted 3D Structures.

6. Genetic analysis of a child with severe intellectual disability caused by a novel variant in the FERM domain of the FRMPD4 protein.

7. Impact of PmrB mutations on clinical Klebsiella pneumoniae with variable colistin-susceptibilities: Structural insights and potent therapeutic solutions.

8. Transactivation by partial function P53 family mutants is increased by the presence of G-quadruplexes at a promoter site.

9. Splicing mutations in AMELX and ENAM cause amelogenesis imperfecta.

10. The extracellular matrix dictates regional competence for tumour initiation.

11. Extension of the DNAJB2a isoform in a dominant neuromyopathy family.

12. Early whole-body mutant huntingtin lowering averts changes in proteins and lipids important for synapse function and white matter maintenance in the LacQ140 mouse model.

13. K-Pro: Kinetics Data on Proteins and Mutants.

14. Association of IL-17F rs2397084 (E126G), rs11465553 (V155I) and rs763780 (H161R) variants with rheumatoid arthritis and their effects on the stability of protein.

15. Predicting pathogenic protein variants.

16. Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1.

17. In silico design and computational evaluation of novel 2-arylaminopyrimidine-based compounds as potential multi-targeted protein kinase inhibitors: application for the native and mutant (T315I) Bcr-Abl tyrosine kinase.

18. Evaluation of phytoconstituents of Tinospora cordifolia against K417N and N501Y mutant spike glycoprotein and main protease of SARS-CoV-2- an in silico study.

19. Discovery of the allosteric inhibitor from actinomyces metabolites to target EGFR CSTMLR mutant protein: molecular modeling and free energy approach.

20. Biochemical characterization of two novel mutations in the human high-affinity choline transporter 1 identified in a patient with congenital myasthenic syndrome.


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