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1. An On-Chip Self-Powered Non-Volatile One-Time-Programmable Memory System in Standard CMOS Technology [2020]

  • Canada, Jorge, Yoshida, Yui, Miura, Hiroki, and Nakano, Nobuhiko
  • 2020 27th IEEE International Conference on Electronics, Circuits and Systems (ICECS) Electronics, Circuits and Systems (ICECS), 2020 27th IEEE International Conference on. :1-4 Nov, 2020

2. Near-Ultrasonic Communications for IoT Applications using Android Smartphone [2020]

  • Hornych, Yann, Toledo, Javier Canada, Wang, Boyang, Yi, Won-Jae, and Saniie, Jafar
  • 2020 IEEE International Conference on Electro Information Technology (EIT) Electro Information Technology (EIT), 2020 IEEE International Conference on. :407-410 Jul, 2020

3. An On-Chip Ultra-Low-Power Hz-Range Ring Oscillator Based on Dynamic Leakage Suppression Logic [2020]

  • Canada, Jorge, Yoshida, Yui, Miura, Hiroki, and Nakano, Nobuhiko
  • 2020 35th International Technical Conference on Circuits/Systems, Computers and Communications (ITC-CSCC) Circuits/Systems, Computers and Communications (ITC-CSCC), 2020 35th International Technical Conference on. :378-383 Jul, 2020

4. Freeman, Frederick Kemper [2000]

  • Canada, Mark
  • American National Biography Online, 2000.

5. English, Thomas Dunn [2000]

  • Canada, Mark
  • American National Biography Online, 2000.

6. An On-Chip Scalable Low Power Consumption High-Voltage Driver Based on Standard CMOS Technology [2020]

  • Canada, Jorge, Yoshida, Yui, Miura, Hiroki, and Nakano, Nobuhiko
  • 2020 International SoC Design Conference (ISOCC) SoC Design Conference (ISOCC), 2020 International. :17-18 Oct, 2020

7. Dynamic security device [2021]

  • NATIONAL RESEARCH COUNCIL OF CANADA and BANK OF CANADA
Abstract
A security device that elicits at least one dynamic response upon acceleration, or upon change of orientation with respect to gravity, wherein the dynamic response continues after cessation of the acceleration or the change of orientation. In addition, the dynamic response can be optical, such that it is visually observable by an unaided human eye. Alternatively, the response can be machine readable. In some cases, the dynamic response has duration of from about 0.01 s to about 100 s, or from about Is to about 10 s.

8. Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance. [2020]

  • Koehler, Philipp, Bassetti, Matteo, Chakrabarti, Arunaloke, Chen, Sharon CA, Colombo, Arnaldo Lopes, Hoenigl, Martin, Klimko, Nikolay, Lass-Flörl, Cornelia, Oladele, Rita O, Vinh, Donald C, Zhu, Li-Ping, Böll, Boris, Brüggemann, Roger, Gangneux, Jean-Pierre, Perfect, John R, Patterson, Thomas F, Persigehl, Thorsten, Meis, Jacques F, Ostrosky-Zeichner, Luis, White, P Lewis, Verweij, Paul E, Cornely, Oliver A, European Confederation of Medical Mycology, International Society for Human Animal Mycology, Asia Fungal Working Group, INFOCUS LATAM/ISHAM Working Group, ISHAM Pan Africa Mycology Working Group, European Society for Clinical Microbiology, Infectious Diseases Fungal Infection Study Group, ESCMID Study Group for Infections in Critically Ill Patients, Interregional Association of Clinical Microbiology and Antimicrobial Chemotherapy, Medical Mycology Society of Nigeria, Medical Mycology Society of China Medicine Education Association, Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology, Association of Medical Microbiology, and Infectious Disease Canada
Subjects
European Confederation of Medical Mycology, International Society for Human Animal Mycology, Asia Fungal Working Group, INFOCUS LATAM/ISHAM Working Group, ISHAM Pan Africa Mycology Working Group, European Society for Clinical Microbiology, Infectious Diseases Fungal Infection Study Group, ESCMID Study Group for Infections in Critically Ill Patients, Interregional Association of Clinical Microbiology and Antimicrobial Chemotherapy, Medical Mycology Society of Nigeria, Medical Mycology Society of China Medicine Education Association, Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology, Association of Medical Microbiology, Infectious Disease Canada, Clinical Sciences, Medical Microbiology, Public Health and Health Services, and Microbiology
Abstract
Severe acute respiratory syndrome coronavirus 2 causes direct damage to the airway epithelium, enabling aspergillus invasion. Reports of COVID-19-associated pulmonary aspergillosis have raised concerns about it worsening the disease course of COVID-19 and increasing mortality. Additionally, the first cases of COVID-19-associated pulmonary aspergillosis caused by azole-resistant aspergillus have been reported. This article constitutes a consensus statement on defining and managing COVID-19-associated pulmonary aspergillosis, prepared by experts and endorsed by medical mycology societies. COVID-19-associated pulmonary aspergillosis is proposed to be defined as possible, probable, or proven on the basis of sample validity and thus diagnostic certainty. Recommended first-line therapy is either voriconazole or isavuconazole. If azole resistance is a concern, then liposomal amphotericin B is the drug of choice. Our aim is to provide definitions for clinical research and up-to-date recommendations for clinical management of the diagnosis and treatment of COVID-19-associated pulmonary aspergillosis.

9. Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients. [2020]

  • Bryant, Laura, Li, Dong, Cox, Samuel G, Marchione, Dylan, Joiner, Evan F, Wilson, Khadija, Janssen, Kevin, Lee, Pearl, March, Michael E, Nair, Divya, Sherr, Elliott, Fregeau, Brieana, Wierenga, Klaas J, Wadley, Alexandrea, Mancini, Grazia MS, Powell-Hamilton, Nina, van de Kamp, Jiddeke, Grebe, Theresa, Dean, John, Ross, Alison, Crawford, Heather P, Powis, Zoe, Cho, Megan T, Willing, Marcia C, Manwaring, Linda, Schot, Rachel, Nava, Caroline, Afenjar, Alexandra, Lessel, Davor, Wagner, Matias, Klopstock, Thomas, Winkelmann, Juliane, Catarino, Claudia B, Retterer, Kyle, Schuette, Jane L, Innis, Jeffrey W, Pizzino, Amy, Lüttgen, Sabine, Denecke, Jonas, Strom, Tim M, Monaghan, Kristin G, DDD Study, Yuan, Zuo-Fei, Dubbs, Holly, Bend, Renee, Lee, Jennifer A, Lyons, Michael J, Hoefele, Julia, Günthner, Roman, Reutter, Heiko, Keren, Boris, Radtke, Kelly, Sherbini, Omar, Mrokse, Cameron, Helbig, Katherine L, Odent, Sylvie, Cogne, Benjamin, Mercier, Sandra, Bezieau, Stephane, Besnard, Thomas, Kury, Sebastien, Redon, Richard, Reinson, Karit, Wojcik, Monica H, Õunap, Katrin, Ilves, Pilvi, Innes, A Micheil, Kernohan, Kristin D, Care4Rare Canada Consortium, Costain, Gregory, Meyn, M Stephen, Chitayat, David, Zackai, Elaine, Lehman, Anna, Kitson, Hilary, CAUSES Study, Martin, Martin G, Martinez-Agosto, Julian A, Undiagnosed Diseases Network, Nelson, Stan F, Palmer, Christina GS, Papp, Jeanette C, Parker, Neil H, Sinsheimer, Janet S, Vilain, Eric, Wan, Jijun, Yoon, Amanda J, Zheng, Allison, Brimble, Elise, Ferrero, Giovanni Battista, Radio, Francesca Clementina, Carli, Diana, Barresi, Sabina, Brusco, Alfredo, Tartaglia, Marco, Thomas, Jennifer Muncy, Umana, Luis, Weiss, Marjan M, Gotway, Garrett, and Stuurman, KE
  • Science advances, vol 6, iss 49
Subjects
DDD Study, Care4Rare Canada Consortium, CAUSES Study, and Undiagnosed Diseases Network
Abstract
Although somatic mutations in Histone 3.3 (H3.3) are well-studied drivers of oncogenesis, the role of germline mutations remains unreported. We analyze 46 patients bearing de novo germline mutations in histone 3 family 3A (H3F3A) or H3F3B with progressive neurologic dysfunction and congenital anomalies without malignancies. Molecular modeling of all 37 variants demonstrated clear disruptions in interactions with DNA, other histones, and histone chaperone proteins. Patient histone posttranslational modifications (PTMs) analysis revealed notably aberrant local PTM patterns distinct from the somatic lysine mutations that cause global PTM dysregulation. RNA sequencing on patient cells demonstrated up-regulated gene expression related to mitosis and cell division, and cellular assays confirmed an increased proliferative capacity. A zebrafish model showed craniofacial anomalies and a defect in Foxd3-derived glia. These data suggest that the mechanism of germline mutations are distinct from cancer-associated somatic histone mutations but may converge on control of cell proliferation.

10. Is Q-Learning Provably Efficient? An Extended Analysis [2020]

  • Rastogi, Kushagra, Lee, Jonathan, Harel-Canada, Fabrice, and Joglekar, Aditya
Subjects
Computer Science - Machine Learning, Computer Science - Artificial Intelligence, Mathematics - Optimization and Control, and Statistics - Machine Learning
Abstract
This work extends the analysis of the theoretical results presented within the paper Is Q-Learning Provably Efficient? by Jin et al. We include a survey of related research to contextualize the need for strengthening the theoretical guarantees related to perhaps the most important threads of model-free reinforcement learning. We also expound upon the reasoning used in the proofs to highlight the critical steps leading to the main result showing that Q-learning with UCB exploration achieves a sample efficiency that matches the optimal regret that can be achieved by any model-based approach.

11. Microelectronic CMOS Implementation of a Machine Learning Technique for Sensor Calibration [2020]

  • Martinez-Nieto, J.A., Sanz-Pascual, M.T., Medrano, N., Lopez, B.C., and Canada, D.A.
  • IEEE Access Access, IEEE. 8:207367-207376 2020

12. Results of the Missouri Quality Initiative in Sustaining Changes in Nursing Home Care: Six-Year Trends of Reducing Hospitalizations of Nursing Home Residents [2021]

  • Vogelsmeier, Amy, Popejoy, L., Canada, K., Galambos, C., Petroski, G., Crecelius, C., Alexander, G. L., and Rantz, M.
  • The journal of nutrition, health & aging. 25(1):5-12

13. A Minimal-Model Approach to Analyze Neuronal Circuit Dynamics from multifocal ERG (mERG) [2019]

  • Schroder, Pascal, Martinez-Canada, Pablo, Amorim, Andre, Fernandes, Paulo, Amorim-de-Sousa, Ana, and Gonzalez-Meijome, Jose Manuel
  • 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Engineering in Medicine and Biology Society (EMBC), 2019 41st Annual International Conference of the IEEE. :2955-2958 Jul, 2019

14. Cohort study with patients older than 80years with stage 5 chronic kidney failure on hemodialysis vs conservative treatment: Survival outcomes and use of healthcare resources [2021]

  • Garcia Testal, Alicia, Garcia Maset, Rafael, Fornes Ferrer, Victoria, Canada Martinez, Antonio J., Fernandez Fandos, Sonia, Rico Salvador, Inmaculada S., Royo Maicas, Pilar, Carretero Lopez, Vanesa, Villalon Coca, Javier, Fernandez Najera, Jose E., Benedito Carrera, Caterina, Olague Diaz, Pau, and Torregrosa De Juan, Eduardo
  • Therapeutic Apheresis and Dialysis. Feb, 2021, Vol. 25 Issue 1, p24, 9 p.

15. Patch panel system with tiltable tray and multiposition lock and release mechanism [2021]

  • BELDEN CANADA ULC
Abstract
A patch panel system is disclosed comprising a plurality of trays wherein each tray is stored within a patch panel housing but moveable towards the front of the housing into one of a patch position or an extended position. The tray is lockable in either the patch position or the extended position. In the extended position a front tray section holding one or more fiber optic connectors or modules is tiltable versus a rear tray section. In particular embodiment the tray can also be moved from the stored position into a retracted position behind the housing. A release mechanism comprising a lock is also provided which can be actuated to release the lock thereby allowing the tray to be slid out of the patch position and the extended position.

16. Energy exchange system for conditioning air in an enclosed structure [2021]

  • Nortek Air Solutions Canada, Inc.
Abstract
An energy exchange system that includes a supply air flow path, an exhaust air flow path, an energy recovery device disposed within the supply and exhaust air flow paths, and a supply conditioning unit disposed within the supply air flow path. The supply conditioning unit may be downstream from the energy recovery device.

17. Heat exchanger for cooling multiple layers of electronic modules [2021]

  • Dana Canada Corporation
Abstract
A stacked-plate heat exchanger for cooling a plurality of heat-generating electronic components arranged in a plurality of layers comprises a stack of flat tubes defining a plurality of parallel fluid flow passages, the tubes being separated by spaces for receiving the electronic components. One or more flow-restricting ribs is arranged within at least some of the fluid flow passages to partially block fluid flow between at least one the manifolds and the heat transfer area by reducing the height of the fluid flow passage outside the heat transfer area, along at least a portion of the width of the fluid flow passage, in order to improve the flow distribution of a heat transfer fluid between and within the fluid flow passages of the heat exchanger, and to minimize bypass flow at the outer edges of the fluid flow passage.

18. Double skin combustor [2021]

  • PRATT & WHITNEY CANADA CORP.
Abstract
There is disclosed a double skin combustor for a gas turbine engine. The combustor has a radially inner liner and a radially outer liner defining therebetween an annular combustion chamber. The radially inner liner and the radially outer liners both have a hot skin and a cold skin defining a cooling cavity therebetween. The cold skin has a plurality of segments joined to one another by sliding joints. The cooling cavity between the hot skin and the cold skin may be compartmentalized into individual cavities between the sliding joints.

19. Small exit duct for a reverse flow combustor with integrated fastening elements [2021]

  • Pratt & Whitney Canada Corp.
Abstract
The described reverse flow combustor of a gas turbine engine includes inner and outer combustor liners defining a combustor chamber therewithin. A large exit duct and a small exit duct are disposed at downstream ends of the outer and inner liner respectively. The small exit duct includes an annular ring removably mounted to a support element of the gas turbine engine by one or more fastening elements that are integrally formed with the annular ring. The fastening elements are mountable with corresponding features of the support element and removably fastened thereto.

20. Non-axisymmetric brush seal assembly [2021]

  • PRATT & WHITNEY CANADA CORP.
Abstract
There is disclosed a brush seal assembly including at least one annular bristle pack. The at least one annular bristle pack extends circumferentially around a central axis of the brush seal assembly. The at least one annular bristle pack has bristles extending along longitudinal axes from roots to free tips. The bristles extend toward a cylindrical plane of a the seal land. Projections of the free tips on the cylindrical plane define a bristle tip projection surface being non-axisymmetric. A method of operating a brush seal assembly is also disclosed.

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