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21. A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers [2020]

  • Jacqueline M. Leung, Eiji Nagayasu, Yu-Chen Hwang, Jun Liu, Phillip G. Pierce, Isabelle Q. Phan, Robin A. Prentice, John M. Murray, and Ke Hu
  • BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-25 (2020)
Subjects
Cytology and QH573-671
Abstract
Abstract Background TgDCX is a doublecortin-domain protein associated with the conoid fibers, a set of strongly curved non-tubular tubulin-polymers in Toxoplasma. TgDCX deletion impairs conoid structure and parasite invasion. TgDCX contains two tubulin-binding domains: a partial P25α and the DCX/doublecortin domain. Orthologues are found in apicomplexans and their free-living relatives Chromera and Vitrella. Results We report that isolated TgDCX-containing conoid fibers retain their pronounced curvature, but loss of TgDCX destabilizes the fibers. We crystallized and determined the 3D-structure of the DCX-domain, which is similar to those of human doublecortin and well-conserved among TgDCX orthologues. However, the orthologues vary widely in targeting to the conoid in Toxoplasma and in modulating microtubule organization in Xenopus cells. Several orthologues bind to microtubules in Xenopus cells, but only TgDCX generates short, strongly curved microtubule arcs. EM analysis shows microtubules decorated with TgDCX bundled into rafts, often bordered on one edge by a “C”-shaped incomplete tube. A Chromera orthologue closely mimics TgDCX targeting in Toxoplasma and binds to microtubules in Xenopus cells, but does not generate arcs or “C”-shaped tubes, and fails to rescue the defects of the TgDCX-knockout parasite. Conclusions These observations suggest that species-specific features of TgDCX enable it to generate strongly curved tubulin-polymers to support efficient host-cell invasion.

22. In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent [2020]

  • Baccarani, Michele, Iacobucci, Ilaria, Chiaretti, Sabina, Foà’, Robin, Balasubramanian, Poonkuzhali, Paietta, Elisabeth, Foroni, Letizia, Jeromin, Sabine, Izzo, Barbara, Spinelli, Orietta, Varma, Neelam, Menif, Samia, Terragna, Carolina, Seth, Tulika, Bidet, Audrey, Coriu, Daniel, Lunghi, Francesca, Mayer, Jiri, Scappini, Barbara, Langabeer, Stephen, Maier, Jacqueline, Burt, Emma, Candoni, Anna, Albano, Francesco, Luppi, Mario, Zupan, Irena, Lion, Thomas, Zadro, Renata, di Raimondo, Francesco, Poopak, Behzad, Rege-Cambrin, Giovanna, Annunziata, Mario, Ayala, Ana, Salinas-Viedma, Victor, Ines Prado, Ana, Milner, Benedict, Galimberti, Sara, Janssen, Jeroen, Polli, Valentina, Comba, Lorenzo, Borsellino, Beatrice, Annibali, Ombretta, Crugnola, Monica, and Passamonti, Francesco
  • Leukemia. 34(3):929-931

23. Piano Music - BOËLY, A.P.F. / CHOPIN, F. / HAYDN, J. / MOSCHELES, I. / WEBER, C.M. von (The Art of the Piano) (Debuchy, Dussaut, Ivaldi, J. Martin) [2019]

  • Dussaut, Therese, Artist, Debuchy, Chantal, Artist, Chauveau, Mélisande, Artist, Martin, Jean, Artist, Ivaldi, Christian, Artist, Robin, Jacqueline, Artist, Lee, Noël, Artist, Boëly, Alexandre Pierre François, Composer, Moscheles, Ignaz, Composer, Weber, Carl Maria von, Composer, Liszt, Franz, Composer, Haydn, Franz Joseph, Composer, Mendelssohn, Felix, Composer, Schumann, Robert, Composer, Chopin, Fryderyk, Composer, and Brahms, Johannes, Composer

24. Cortical tracking of speech in noise accounts for reading strategies in children [2020]

  • Destoky, Florian, Bertels, Julie, Niesen, Maxime, Wens, Vincent, Vander Ghinst, Marc, Leybaert, Jacqueline, Lallier, Marie, Ince, Robin A. A., Gross, Joachim, De Tiege, Xavier, Bourguignon, Mathieu, and Gasque, Gabriel
  • PLoS Biology. August 26, 2020, Vol. 18 Issue 8, e3000840

25. JOLIVET, A.: Hymne à St. André / Hymne à l'univers / Arioso barocco / Mandala / Nocturne (Barraud, Pénassou, Périnelli, Robin, D. Roth) [2019]

  • Pénassou, Pierre, Artist, Barraud, Dany, Artist, Robin, Jacqueline, Artist, Roth, Daniel, Artist, Périnelli, René, Artist, and Jolivet, André, Composer

26. BANYAN. XI. The BANYAN $\Sigma$ multivariate Bayesian algorithm to identify members of young associations within 150 pc [2018]

  • Gagné, Jonathan, Mamajek, Eric E., Malo, Lison, Riedel, Adric, Rodriguez, David, Lafrenière, David, Faherty, Jacqueline K., Roy-Loubier, Olivier, Pueyo, Laurent, Robin, Annie C., and Doyon, René
Subjects
Astrophysics - Solar and Stellar Astrophysics
Abstract
BANYAN $\Sigma$ is a new Bayesian algorithm to identify members of young stellar associations within 150 pc of the Sun. It includes 27 young associations with ages in the range ~1-800 Myr, modelled with multivariate Gaussians in 6-dimensional XYZUVW space. It is the first such multi-association classification tool to include the nearest sub-groups of the Sco-Cen OB star-forming region, the IC 2602, IC 2391, Pleiades and Platais 8 clusters, and the $\rho$ Ophiuchi, Corona Australis, and Taurus star-formation regions. A model of field stars is built from a mixture of multivariate Gaussians based on the Besan\c{c}on Galactic model. The algorithm can derive membership probabilities for objects with only sky coordinates and proper motion, but can also include parallax and radial velocity measurements, as well as spectrophotometric distance constraints from sequences in color-magnitude or spectral type-magnitude diagrams. BANYAN $\Sigma$ benefits from an analytical solution to the Bayesian marginalization integrals that makes it more accurate and significantly faster than its predecessor BANYAN II. A contamination versus hit rate analysis is presented and demonstrates that BANYAN $\Sigma$ achieves a better classification performance than other moving group classification tools, especially in terms of cross-contamination between young associations. An updated list of bona fide members in the 27 young associations, augmented by the Gaia-DR1 release, are presented. This new tool will make it possible to analyze large data sets such as the upcoming Gaia-DR2 to identify new young stars. IDL and Python versions of BANYAN $\Sigma$ are made available with this publication. (shortened)
Comment: 52 pages, 12 figures, 11 tables. Accepted for publication in the Astrophysical Journal Supplement Series. Minor corrections and updated URLs

27. Early Experiences With COVID-19 Testing in Transplantation [2020]

  • Brian J. Boyarsky, MD, Allan B. Massie, PhD, Arthur D. Love, BS, William A. Werbel, MD, Christine M. Durand, MD, Robin K. Avery, MD, Kyle R. Jackson, MD, PhD, Amber B. Kernodle, MD, MPH, Alvin G. Thomas, MSPH, Matthew Ronin, BA, Michelle Altrich, PhD, Patricia Niles, BS, RN, Chad Trahan, BSN, Jonathan Hewlett, BA, Dorry L. Segev, MD, PhD, and Jacqueline M. Garonzik-Wang, MD, PhD
  • Transplantation Direct, Vol 6, Iss 7, p e572 (2020)
Subjects
Surgery and RD1-811
Abstract
Background. The early effects of coronavirus disease 2019 (COVID-19) on transplantation are dramatic: >75% of kidney and liver programs are either suspended or operating under major restrictions. To resume transplantation, it is important to understand the prevalence of COVID-19 among transplant recipients, donors, and healthcare workers (HCWs) and its associated mortality. Methods. To investigate this, we studied severe acute respiratory syndrome coronavirus 2 diagnostic test results among patients with end-stage renal disease or kidney transplants from the Johns Hopkins Health System (n = 235), and screening test results from deceased donors from the Southwest Transplant Alliance Organ Procurement Organization (n = 27), and donors, candidates, and HCWs from the National Kidney Registry and Viracor-Eurofins (n = 253) between February 23 and April 15, 2020. Results. We found low rates of COVID-19 among donors and HCWs (0%–1%) who were screened, higher rates of diagnostic tests among patients with end-stage renal disease or kidney transplant (17%–20%), and considerable mortality (7%–13%) among those who tested positive. Conclusions. These findings suggest the threat of COVID-19 for the transplant population is significant and ongoing data collection and reporting is critical to inform transplant practices during and after the pandemic.

28. A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers [2020]

  • Leung, Jacqueline M., Nagayasu, Eiji, Hwang, Yu-Chen, Liu, Jun, Pierce, Phillip G., Phan, Isabelle Q., Prentice, Robin A., Murray, John M., and Hu, Ke
  • BMC Molecular and Cell Biology. 21(1)

29. eBP : A Wearable System For Frequent and Comfortable Blood Pressure Monitoring From User's Ear [2019]

  • Nam Bui, Nhat Pham, Jessica Jacqueline Barnitz, Zhanan Zou, Phuc Nguyen, Hoang Truong, Taeho Kim, Nicholas Farrow, Anh Nguyen, Jianliang Xiao, Robin Deterding, Thang Dinh, and Tam Vu
  • Mobile Computing and Networking. :1-17

30. Parental drinking in Australia: Does the age of children in the home matter? [2019]

  • Bowden, Jacqueline A., Delfabbro, Paul, Room, Robin, Miller, Caroline, Wilson, Carlene, and Stockholms universitet, Samhällsvetenskapliga fakulteten, Institutionen för folkhälsovetenskap, Centrum för socialvetenskaplig alkohol- och drogforskning (SoRAD)
  • Drug and Alcohol Review. 38(3):306-315
Subjects
Medical and Health Sciences, Health Sciences, Substance Abuse, Medicin och hälsovetenskap, Hälsovetenskaper, Beroendelära, alcohol, parents, and consumption
Abstract
Introduction and Aims Parental role modelling of alcohol use is known to influence alcohol consumption in adolescence and in later life. This study aimed to assess relationships between parental status, child age and alcohol consumption, which have not been well documented. Design and Methods Data were sourced from the 2013 Australian National Drug Strategy Household Survey. Analyses were conducted for 25-55 year olds (n = 11 591) by parental status, gender and age of youngest child in the household, controlling for socio-demographic factors. Results Parents were less likely than non-parents to exceed the alcohol guideline for increased lifetime risk (18.2% vs. 24.2%) and short-term risk: at least weekly (14.2% vs. 21.2%); and at least monthly (27.5% vs. 35.9%). Fathers were just as likely to exceed the guidelines for lifetime risk as other men, but those with children aged 0-2, were less likely to exceed the guideline for short-term risk. Women were least likely to exceed the guideline for lifetime risk if they had children aged 0-2, 6-11 or 15 years and over, or the guideline for short-term risk, if they had children aged 0-2, or 15 years and over in the household. Parents were more likely to report drinking in the home. Discussion and Conclusions Parents were less likely to exceed alcohol guidelines than non-parents, especially mothers whose youngest child was an infant or in high school or older. Consistent with population rates in men, fathers were more likely to exceed alcohol guidelines than mothers, and this excess consumption warrants public health attention.

31. Automated typing of red blood cell and platelet antigens from whole exome sequences [2019]

  • Lane, William J., Vege, Sunitha, Mah, Helen H., Lomas-Francis, Christine, Aguad, Maria, Smeland-Wagman, Robin, Koch, Christopher, Killian, Jacqueline M., Gardner, Cubby L., De Castro, Mauricio, Lebo, Matthew S., Kaufman, Richard M., Green, Robert C., and Westhoff, Connie M.
  • Transfusion. Oct 2019, Vol. 59 Issue 10, p3253, 11 p.

32. Predictors of low birth weight and preterm birth in rural Uganda: Findings from a birth cohort study [2020]

  • Bater, Jorick, Lauer, Jacqueline M., Ghosh, Shibani, Webb, Patrick, Agaba, Edgar, Bashaasha, Bernard, Turyashemererwa, Florence M., Shrestha, Robin, and Duggan, Christopher P.
  • PLoS ONE. July 13, 2020, Vol. 15 Issue 7, e0235626

33. The regulatory landscape of biosimilars: WHO efforts and progress made from 2009 to 2019 [2020]

  • Kang, Hye-Na, Thorpe, Robin, Knezevic, Ivana, Blades, Carolina Damas Rocha Zarate, Casas Levano, Mary, Chew, Jing Yin, Chilufya, Mumbi Bernice, Chirachanakul, Parichard, Chua, Hui Ming, Farahani, Ali Vasheghani, Ghobrial, Mariam Raouf Wefky, Habahbeh, Suna, Hamel, Hugo, Kim, Gi Hyun, Perez Rodriguez, Violeta, Putri, Desi Eka, Rodgers, Jacqueline, Savkina, Maria, Semeniuk, Oleh, Srivastava, Shraddha, Wadhwa, Meenu, and Yamaguchi, Teruhide
  • Biologicals. May 2020, Vol. 65, 1

34. Predictors of low birth weight and preterm birth in rural Uganda: Findings from a birth cohort study [2020]

  • Jorick Bater, Jacqueline M Lauer, Shibani Ghosh, Patrick Webb, Edgar Agaba, Bernard Bashaasha, Florence M Turyashemererwa, Robin Shrestha, and Christopher P Duggan
  • PLOS ONE, 2020, 15, 7, 1.
Abstract
Background: Approximately 20.5 million infants were born weighing 150 cm) (adjusted Odds Ratio (aOR) = 0.42 (95% CI = 0.24, 0.72)), multigravida (aOR = 0.62 (95% CI = 0.39, 0.97)), or with adequate birth spacing (>24 months) (aOR = 0.60 (95% CI = 0.39, 0.92)) had lower odds of delivering a LBW infant Mothers with severe household food insecurity (aOR = 1.84 (95% CI = 1.22, 2.79)) or who tested positive for malaria during pregnancy (aOR = 2.06 (95% CI = 1.10, 3.85)) had higher odds of delivering a LBW infant. In addition, in multivariable analysis, mothers who resided in the Southwest (aOR = 0.64 (95% CI = 0.54, 0.76)), were ≥20 years old (aOR = 0.76 (95% CI = 0.61, 0.94)), with adequate birth spacing (aOR = 0.76 (95% CI = 0.63, 0.93)), or attended ≥4 antenatal care (ANC) visits (aOR = 0.56 (95% CI = 0.47, 0.67)) had lower odds of delivering a preterm infant; mothers who were neither married nor cohabitating (aOR = 1.42 (95% CI = 1.00, 2.00)) or delivered at home (aOR = 1.25 (95% CI = 1.04, 1.51)) had higher odds. Conclusions: In rural Uganda, severe household food insecurity, adolescent pregnancy, inadequate birth spacing, malaria infection, suboptimal ANC attendance, and home delivery represent modifiable risk factors associated with higher rates of LBW and/or preterm birth. Future studies on interventions to address these risk factors may be warranted.

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38. Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms [2019]

  • Jones, Samuel E., Lane, Jacqueline M., Wood, Andrew R., van Hees, Vincent T., Tyrrell, Jessica, Beaumont, Robin N., Jeffries, Aaron R., Dashti, Hassan S., Hillsdon, Melvyn, Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Sharp, Seth A., Jie, Yingjie, Thompson, William D., Harrison, Jamie W., Dawes, Amy, Byrne, Enda M., Tiemeier, Henning, Allebrandt, Karla V., Bowden, Jack, Ray, David W., Freathy, Rachel M., Murray, Anna, Mazzotti, Diego R., Gehrman, Philip R., Lawlor, Debbie A., Frayling, Timothy M., Rutter, Martin K., Hinds, David A., Saxena, Richa, and Weedon, Michael N.
  • Nature Communications. 10(1)

39. A Human Hematopoietic Niche Model Supporting Hematopoietic Stem and Progenitor Cells In Vitro [2019]

  • Braham, Maaike V. J., Li Yim, Amelie S. P., Garcia Mateos, Jara, Minnema, Monique C., Dhert, Wouter J. A., Oner, F. Cumhur, Robin, Catherine, and Alblas, Jacqueline
  • Advanced Healthcare Materials. May 23, 2019, Vol. 8 Issue 10, n/a

40. Community stakeholders’ perspectives on the role of occupational therapy in primary healthcare : implications for practice [2017]

  • Van Wyk Jacqueline, Naidoo Deshini, and Joubert Robin
  • African Journal of Disability, Nov 2017, Vol 6, Issue 1, p. 1-12.

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