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Tumor markers, Oncology, Biochemical markers, and Cancer--Treatment

Cancer is a term that describes a constellation of diseases that affect a large proportion of the global population. By 2020, it is estimated there will be 15 million new cancer cases worldwide and a corresponding 12 million cancer-related deaths. There are many efficacious treatments for cancer with both curative and palliative intents, which regardless of efficacy, can result in distressing symptoms including pain, fatigue, nausea, vomiting, and reduced function. Compounded with very similar symptoms from the disease itself, toxicities can ultimately lead to diminished quality of life (QOL). In recent years, the use of biomarkers in cancer research and practice has become a widely discussed topic of exploration for researchers and clinicians alike. A biomarker is a biological property that can be measured and used as a tool in the prevention, diagnosis, and treatment of specific illnesses, including cancer. In this book, the authors synthesize existing biomarker research in the literature related to cancer and the potential effect it may have on future treatment, drug metabolism, symptom burden, radiation response, susceptibility to radiation related toxicities, and prognosis.

Cancer--Treatment, Oncology, and Oncologists

Oncology: Strategies for Superior Service Line Performance ECG Management Consultants, Inc.; Matthew R. Sturm; Jessica L. Turgon The evolution of the oncology payment model and pressure to provide more patient-centered care are leading many healthcare organizations to transform the oncology care model in their communities by offering more coordinated and comprehensive services that provide high quality for patients and high value to payers. Hospitals and health systems are developing service line structures that improve clinical and financial performance, encourage physician involvement, and create a distinct brand in the market—ultimately gaining a competitive advantage. Gain realistic strategies and business guidance from oncology leaders to develop the structures and processes for oncology service line success, including how to: Navigate the challenges of oncology reimbursementAchieve clinical integration in the oncology care modelCreate aligned physician relationshipsSimplify strategic planning for oncology servicesCapitalize on clinical research opportunitiesEstablish multidisciplinary teams and support services that improve quality and access to careTable of contents Chapter 1: Strategic Planning for Oncology Services Step 1: Understanding the Content of an Oncology Strategic PlanStep 2: Planning to Plan: How to Get From Here to ThereStep 3: Learning About the Organization’s Capabilities and the MarketStep 4: Identifying What the Organization Wants to AccomplishStep 5: Making It HappenChapter 2: Creating a Successful Oncology Service Line Introduction to Service Line PrinciplesKey Elements for Service Line SuccessImplementation IssuesThe Future for Oncology Service LineChapter 3: The Importance of Governance and Leadership Oncology Governance StructuresOncology Service Line LeadershipManaging PerformanceChapter 4: Creating Aligned Physician Relationships Affiliation ModelsPhysician Alignment Planning ProcesChapter 5: Key Elements of a Successful Oncology Transaction Definition of the Transaction GoalsBusiness PlanningDevelopment of the Organizational StructureDevelopment of Key TermsImplementationChapter 6: Navigating the Challenges of Oncology ReimbursementKeys to Oncology Reimbursement: Legislation, Drugs, Professional FeesImplications for HospitalsOther Reimbursement TrendsChapter 7: Clinical Integration and the Oncology Care Model Coordinating Cancer Care: The Importance of the Navigator RoleNew Approach to Treatment Planning: Multidisciplinary CareComplementary and Alternative MedicinChapter 8: Academic Cancer Centers Clinical Departments and Implications for Academic Cancer CentersGovernance Models in AMCsCall for AMC-Wide Financial Integration Chapter 9: Maximizing Clinical Research Operations Research OverviewBest Practices in Research Program PlanningWhy Billing for Clinical Trials Is So ComplexThe Nuts and Bolts of Billing for Clinical TrialsThe Last Step: Audit Process and Performance

Cancer--Interventional radiology and Cancer--Radiotherapy

Interventional Oncology is a concise, practical guide to state-of-the-art, image-guided procedures that are among the most innovative and effective cancer treatment options available today. Each chapter is presented in a similar format that includes indications, contraindications, patient selection, pre-procedure workup, technique, post procedure management, and clinical data. This book is the perfect high-yield manual for practitioners to consult before seeing oncology patients, as well as for intra and post-procedure management.Key Features:High-quality color illustrations and multi-modality clinical imagesCovers all the latest interventional oncology proceduresChapter authors are leading authorities in the fieldTips and pearls at the end of each chapter and a comprehensive set of referencesThis book is an excellent clinical guide for seasoned interventional radiologists as well as trainees in interventional oncology to consult on a day–to–day basis.

Brain--Cancer

Neuro-Oncology: The Essentials, Third Edition, is a comprehensive introduction to the fundamental science and core clinical concepts behind the successful multidisciplinary management of patients with brain and spine tumors. Among the updates to this new edition are eight new chapter topics, including: Endoscopic Approaches, Pediatric Supratentorial Tumors, and Neuro-Oncology in the Developing World. The book begins with basic science, progresses to clinical applications, and includes a robust section on specific tumor types.Key Features:A major revision, with a 20% increase in content and over 35% increase in figuresEditors Notes at the end of each chapter briefly summarize a topic, provide a historical perspective on a topic, add a current reference, or highlight salient points Demonstrates the latest surgical navigation techniques, including stereotaxy and intraoperative MRI, used to access hard-to-reach tumors This new edition is an invaluable reference for all neurosurgeons, neurologists, and oncologists, as well as residents and fellows, and it will be a treasured volume in their medical libraries for years to come.

Cancer--Radiotherapy and Cancer--Radionuclide imaging

Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the management of the patient with a malignant tumor and in some cases, even benign neoplasms. The standard of practice for many tumors requires PET/CT imaging at various stages of diagnosis and management. In addition to clinical applications, ongoing investigational efforts, which more and more involve multi-institutional protocols, are also presented. Features: • Focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases • Emphasizes SPECT/CT and PET/CT with additional emphasis on the potential application of PET/MR • Describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology

Tumors--Nursing--Handbooks, manuals, etc, Mental health services--Handbooks, manuals, etc, and Tumors--Psychology--Handbooks, manuals, etc

Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs.This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.

Integrative medicine, Cancer--Adjuvant treatment, and Cancer--Alternative treatment

More and more people living with and beyond cancer seek integrative interventions to complement their conventional cancer care. This second edition of the highly successful Integrative Oncology provides the reader with the most updated information available with new chapters on Music and Expressive Arts Therapies, Naturopathic Oncology, and an integrative approach to Lung Cancer. Integrative medicine is defined as healing-oriented medicine that takes account of the whole person (body, mind, and spirit) as well as all aspects of lifestyle; it emphasizes the therapeutic relationship and makes use of appropriate therapies, both conventional and alternative. This series grows out of a need to organize and make accessible to clinicians the basic principles of integrative medicine in practical application to common health conditions. Each volume focuses on a particular specialty and features well-recognized and authoritative editors and chapter authors. The text is presented in an easy-to-read format featuring case histories, clinical pearls, and useful tables, with all key information highlighted. Series editor Andrew Weil, MD, is Professor and Director of the Arizona Center for Integrative Medicine at the University of Arizona. Dr. Weil's program was the first such academic program in the U.S., and its stated goal is'to combine the best ideas and practices of conventional and alternative medicine into cost effective treatments without embracing alternative practices uncritically.'

Cancer--Radiotherapy

Radiation Oncology provides residents, fellows, and clinicians with a practical, evidence-based guide to the current management of difficult cases in radiation oncology. Emphasis is on the management of those clinical challenges commonly seen in practice that the community practitioner would normally handle without outside referral. The book offers comparisons of treatment approaches to difficult situations, allowing the reader to compare their current treatment approach to that of experts and others in the community.Radiation Oncology is organized in seven sections corresponding to the major treatment areas of radiation oncology. Each section includes three cases to illustrate specific clinical challenges for which there is no clear treatment protocol. The case discussion includes an expert opinion on optimal management along with alternatives from a second academic expert's perspective and from a community practitioner's perspective. Radiation Oncology features: Evidence-based approach to difficult management challenges in radiation oncology Expert authors provide evidence assessment and management summaries through presentation of relevant cases Community practitioner reviewers ensure real-world relevance of each discussion Reviews the most relevant literature pertaining to the challenging scenarios clinicians encounter every day Management alternatives allow discussion of the full range of management options and specifics for difficult problems including hardline recommendations

Cancer--Psychological aspects and Cancer--Patients--Care

Psycho-oncology integrates research and clinical wisdom across multiple disciplines -- including oncology, psychiatry, psychology, surgery, radiotherapy and palliative care, among others -- in the service of educating oncologists, physicians, psychiatrists and other mental health care providers, and hospital chaplains about the psychological and psychosocial challenges faced by patients with neoplastic disorders. As cancer treatment has improved, the number of patients deemed'cancer survivors'has grown, along with their more complex, long-term mental health issues. This book assists care providers in meeting the challenge presented by this population. Written by international experts in psycho-oncology, the volume offers a compact overview of the clinical elements in this field, with a primary focus on the biopsychosocial aspects of individuals with cancer as well as their families and important people in their lives. Its'bench-to-bedside'approach ensures that the techniques presented are evidence-based, practical, and effective. The following are among the book's many helpful features: The chapters are designed to stand alone, to be shared or consulted as needed, but they also develop a coherent and sequential discussion about management of the patient with cancer, as well as concerns involving the patient's family. Thus, the book as a whole serves as a comprehensive textbook in the field. The book's structure is based on psychosocial staging, much as the disease itself is staged, and progresses from discovery to initial diagnosis, treatment intervention, remission, and so forth. Each phase has its own challenges -- for patient, family, and care provider -- and supportive strategies are offered. Because identifying those patients in need of support and treatment intervention is critical, the authors provide screening techniques, as well as an entire chapter devoted to quality of life assessment, to help clinicians recognize struggling patients and alleviate their distress. A final chapter addresses developing trends in psycho-oncology and suggests that international standards of care for the cancer patient must include competent and compassionate psychosocial assessment and treatment. Concise and clinically focused, yet addressing the broad issues as well, Psycho-oncology offers cutting-edge information and invaluable assistance to physicians and mental health professionals responsible for managing patients, and the families of patients, with neoplastic disorders.

Nanotechnology--Congresses, Cancer--Treatment--Congresses, Nanomedicine--Congresses, and Oncology--Research--United States--Congresses

One way scientists are working to overcome challenges in cancer treatment and improve cancer care is through nanotechnology. Nanotechnology, engineered materials that make use of the unique physical properties, presents a new array of medical prospects that will revolutionize cancer prevention, diagnosis, and treatment practices. Giving new hope to patients, practitioners, and researchers alike, nanotechnology has the potential to translate recent discoveries in cancer biology into clinical advances in oncology. While public investments in nanotechnology for cancer continue to increase, medical products based on nanotechnology are already on the market. The National Cancer Policy forum held a workshop July 12-13, 2010, to explore challenges in the use of nanotechnology in oncology. Nanotechnology and Oncology evaluates the ongoing discussion on the role of nanotechnology in cancer as it relates to risk management, treatment, and regulatory policy. Assessments on nanomedicine and the physical properties of nanomaterials were presented during the workshop, along with an appraisal of the current status of research and development efforts.

Cancer--Psychological aspects and Cancer--Patients--Mental health

Psycho-Oncology was the first comprehensive text in the field of psychosocial oncology and remains the gold standard today. Written by 67 internationally known psychiatry and palliative care experts, the resource is truly an essential reference for all providers of palliative care. Joining Oxford Medicine Online this resource offers the best quality content in an easy-to-access format. Online only benefits include downloading images and figures to PowerPoint and downloading chapters to PDF.

Integrative medicine, Oncology, Cancer--Alternative treatment, and Cancer--Adjuvant treatment

People facing a new diagnosis of cancer are unsettled by their prognosis and treatment options, and they often seek to integrate complementary modalities into their conventional care plan, hoping to improve their chances of cure and decrease side effects. Many do so without informing their oncologist, for fear of alienating them or not convinced that their physician would be informed about complementary therapies. Integrative Oncology, the first volume in the Weil Integrative Medicine Library, provides a wealth of information for both practitioners and consumers on the emerging field of integrative oncology. Noted oncologist Donald Abrams and integrative medicine pioneer Andrew Weil and their international panel of experts present up-to-date and extensively referenced chapters on a wide spectrum of issues and challenges, bound in one comprehensive, reader-friendly text in a format featuring key points, sidebars, tables, and a two-color design for ease of use. It is destined to emerge as the definitive resource in this emerging field.

Generative organs, Female--Surgery, Generative organs, Female--Cancer, Evidence-based medicine, and Clinical medicine--Decision making

New edition fully includes Grades and Levels of evidence, providing a better idea of what the sum total of existing evidence suggests regarding key topics Grades and levels of evidence consistently highlighted throughout Greater number of tables and algorithms ('decision trees') for key decision-making areas'Scope of concept'introduction to chapters are significantly enhanced, allowing the reader to reference the concepts while reviewing the specific details in the clinically oriented chapters The only available book with an evidence-based approach covering this specific subject matter in one compendium

Cancer--Surgery--Handbooks, manuals, etc

How should surgeons deal with cancer patients? The cornerstone of effective treatment is a multidisciplinary collaboration between many specialties in which surgeons are not only concerned about operative accessibility and technique but rather have a deep understanding of the fundamental biology of the malignancy they are dealing with and appreciate the reach of multi-modal treatment. This handbook is a practical reference for today's surgeons who actively manage cancer patients in both the acute and out-patient setting. It covers all the key areas, from initial presentation and diagnosis, investigation and staging, to active discussion in collaborative multidisciplinary cancer network meetings, operative management, post-operative care, and long term surveillance and palliation. Drawing together all the varied guidelines and source materials that form the basis of this complex subject, it is the first surgical oncology text that provides instant access to detailed clinical algorithms and operative techniques covering the wide range of cancers that general surgeons encounter, from GI tract to breast and endocrine cancers. Consistently sourced from current evidence based guidelines with a concise summary of underlying pathology and molecular biology, Surgical Oncology will enable the reader to knowledgably manage cancer patients from initial assessment to long term surveillance. It is an essential accompaniment for all higher surgical trainees from MRCS to the exit FRCS and EBSQ exams, and will be particularly useful for trainees rotating between surgical subspecialties, as well as having wide appeal to other members of the multidisciplinary team.

Cancer--Adjuvant treatment and Cancer--Alternative treatment

One of every four deaths occurring in the United States today is due to cancer, and the number of diagnoses continues to increase. Fortunately, however, cancer treatments are improving, which means more and more patients are surviving for longer periods. Complementary methods have played an important role in these treatments, showing benefits such as a higher quality of life, reduced instance and severity of the side effects of standard therapy, and a general improvement of the patient's immunological state. Indeed, these methods - from carefully monitored nutrition, exercise, and psychological support to enzyme substitution, phytotherapy, hyperthermia and microbiology therapy - are critical to a treatment's overall success. More than ever, doctors need accurate, up-to-date information about which methods have been proven in scientifically based clinical studies (EBM) to be acceptable for use in conjunction with standard treatment methods. In this unique book, experts ranging across medical disciplines present data on the efficacy of these methods as they are currently being used, the necessary scientific background, and practical advice for introducing them into practice. With illustrations, tables, and detailed descriptions, this book is an ideal reference and an invaluable tool for educating patients about this encouraging aspect of cancer therapy. Throughout, the contributors emphasize the latest scientifically and clinically tested treatments. A useful chart lays out in detail which treatments are applicable for various types of cancers and what effects they have been shown to cause. The word is out about the beneficial qualities of complementary therapies in the treatment of cancer. More physicians are offering it to their patients, and more and more patients are demanding it. You - and your patients - cannot afford to be without this valuable resource.

Cancer--Treatment

Precision medicine is rapidly becoming the standard-of-care for the treatment of cancer patients. This is made possible, in part, by the ready availability and reasonable costs of comprehensive DNA and RNA sequencing assays. However, precision medicine is complex and incorporates entirely new types of data and treatment paradigms that are outside of the training of most oncologists in practice today. Precision Medicine Oncology: A Primer is a concise review of the fundamental principles and applications of precision medicine, intended for clinicians, particularly those working in oncology. It provides an accessible introduction to the technological advances in DNA and RNA sequencing, gives a detailed overview of approaches to the interpretation of molecular test results and their point-of-care implementation for individual patients, and describes innovative clinical trial designs in oncology as well as characteristics of the computational infrastructures through which massive quantities of data are collected, stored, and used in precision medicine oncology.

Gastrointestinal system--Cancer

In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of the specific cancers affecting the human gastrointestinal tract. These chapters are introduced by state of the art discussions outlining our current understanding of the pathobiology and molecular biology relevant to each cancer. Subsequent sections describe the multidisciplinary management of specific clinical situations. By organizing the treatment-related chapters around clinical scenarios, the reader will readily find the information necessary to effectively manage the complex clinical situations encountered by patients with gastrointestinal malignancies.

Cancer--Handbooks, manuals, etc and Oncology--Handbooks, manuals, etc

Concise, portable, and packed with essential information, Manual of Clinical Oncology is an indispensable resource for understanding basic science, clinical findings, and available technology as they relate to the diagnosis and management patients with cancer. The practical format provides high-yield content useful for participating in rounds ad making diagnostic and therapeutic decisions at the bedside. Edited by Dr. Bartosz Chmielowski and Dr. Mary Territo, both from UCLA School of Medicine, this eighth edition carries on the tradition of excellence set forth by longtime editor Dr. Dennis Casciato. Incorporates recent major achievements in immunotherapies, biologics, and targeted therapies. Features new chapters on the biology of cancer, immunotherapy, and cancer survivorship. Contains numerous diagnostic and treatment algorithms, as well as content on complications, for assistance with clinical decision making. Includes helpful appendices such as a glossary of cytogenetic nomenclature and combination chemotherapy regimens. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time — providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click

Cancer--Treatment--Technological innovations and Cancer--Radiotherapy

Precision medicine is a rapidly-evolving field in the management of cancer. The use of novel molecular or genetic signatures in local-regional management is still in its infancy. Precision Radiation Oncology demystifies this state-of-the-art research and technology. By describing current existing clinical and pathologic features, and focusing on the ability to improve outcomes in cancer using radiation therapy, this book discusses incorporating novel genomic- or biology-based biomarkers in the treatment of patients moving radiation oncology into precision/personalized medicine. Precision Radiation Oncology provides readers with an overview of the new developments of precision medicine in radiation oncology, further advancing the integration of new research findings into individualized radiation therapy and its clinical applications.

Generative organs, Female--Cancer--Handbooks, manuals, etc

Now in its second edition, Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide has been thoroughly updated to include the latest advances in surgical techniques, chemotherapy protocols, AJCC 8th Edition staging criteria, and much more. This current edition contains illustrations that reinforce key concepts, algorithms for diagnostic techniques, and tables to guide you in optimal disease management.The handbook covers the spectrum of gynecologic oncology from seminal studies to guide the oncologist, to the essential workup for the Obstetrician/Gynecologist and related clinician. This handbook can be carried by the practitioner on the ward or in the clinic. It includes necessary details on gynecologic cancer screening and treatment regimens for preinvasive disease, to staging and management of all the gynecologic cancers such as cervical cancer, ovarian cancer, uterine cancer, vulvar cancer, vaginal cancer, and gestational trophoblastic disease. It highlights evidence-based best practices for managing these cancers, hereditary cancer syndromes, for surgical care, and for all adjuvant therapies including chemotherapy, radiation therapy, targeted therapies, and immunotherapies. Detailed sections on survivorship care, palliative care, as well as managing reproductive function and other comorbid medical conditions make this a ‘one-stop shop'for navigating all clinical aspects and effects of gynecologic cancer.Featuring new and important clinical study references, medical comorbidity algorithms, directed gynecologic cancer workups and treatments, numerous tables and easy-to-reference illustrations, the Gynecologic Oncology Handbook, 2nd Edition is the ultimate quick reference for the clinical management of all gynecologic malignancies and related conditions.Key Features:Covers all fundamentals of gynecologic oncology including workup, staging, surgical management, chemotherapy and radiation therapy treatment, comorbidity diagnosis and management, and background study dataProvides Gynecologic Oncology Referral Parameters, Performance Status Scales, Adverse Event Grading, RECIST evaluation criteria, chemotherapy protocols, statistics, and other useful formulas. Includes clinical study references, medical comorbidity algorithms, directed workups, and treatment guidelines