BMJ Case Reports [BMJ Case Rep] 2015 Aug 13; Vol. 2015. Date of Electronic Publication: 2015 Aug 13.
Herpes Zoster surgery, Herpes Zoster virology, Herpesvirus 3, Human genetics, Herpesvirus 3, Human isolation purification, Humans, Male, Splenectomy, Splenic Rupture surgery, Young Adult, Herpes Zoster diagnosis, and Splenic Rupture virology
A 22-year-old man presented with a 1-day history of severe abdominal pain. He developed a generalised vesicular rash 12 h prior to admission. On examination, he was maximally tender with peritonism in the lower abdomen. Working diagnosis was perforated appendix and a decision to investigate with CT was made, which showed intra-abdominal haemorrhage likely arising from a ruptured spleen. After a period of observation, he subsequently underwent laparotomy and emergency splenectomy. Viral PCR from vesicular fluid was positive for varicella zoster virus. Viral serology was otherwise negative. (2015 BMJ Publishing Group Ltd.)