Al Shaer D, Al Musaimi O, Albericio F, and de la Torre BG
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2019 Apr 05; Vol. 12 (2). Date of Electronic Publication: 2019 Apr 05.
In 2018, the United States Food and Drug Administration (FDA) approved a total of 59 new drugs, three of them (5%) are TIDES (or also, -tides), two oligonucleotides and one peptide. Herein, the three TIDES approved are analyzed in terms of medical target, mode of action, chemical structure, and economics.
Al Musaimi O, Al Shaer D, de la Torre BG, and Albericio F
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2018 May 07; Vol. 11 (2). Date of Electronic Publication: 2018 May 07.
2017 was an excellent year in terms of new drugs (chemical entities and biologics) approved by the FDA, with a total of 46. In turn, one of the highlights was the number of peptides (six) included in this list. Here, the six peptides are analyzed in terms of chemical structure, synthetic strategy used for their production, source, therapeutic use, and mode of action.