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Daix, Thomas, Mathonnet, Armelle, Brakenridge, Scott, Dequin, Pierre-François, Mira, Jean-Paul, Berbille, Frederique, Morre, Michel, Jeannet, Robin, Blood, Teresa, Unsinger, Jacqueline, Blood, Jane, Walton, Andrew, Moldawer, Lyle L., Hotchkiss, Richard, and Francois, Bruno
- Annals of Intensive Care. December, 2023, Vol. 13 Issue 1
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Zannad F, Alikhaani J, Alikhaani S, Butler J, Gordon J, Jensen K, Khatib R, Mantovani L, Martinez R, Moore WF, Murakami M, Roessig L, Stockbridge N, Van Spall HGC, Yancy C, and Spertus JA
European journal of heart failure [Eur J Heart Fail] 2023 Mar 16. Date of Electronic Publication: 2023 Mar 16.
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There are many consequences of heart failure (HF), including symptoms, impaired health-related quality of life (HRQoL), and physical and social limitations (functional status). These have a substantial impact on patients' lives, yet are not routinely captured in clinical trials. Patient-reported outcomes (PROs) can quantify patients' experiences of their disease and its treatment. Steps can be taken to improve the use of PROs in HF trials, in regulatory and payer decisions, and in patient care. Importantly, PRO measures (PROMs) must be developed with involvement of patients, family members, and caregivers from diverse demographic groups and communities. PRO data collection should become more routine not only in clinical trials but also in clinical practice. This may be facilitated by the use of digital tools and interdisciplinary patient advocacy efforts. There is a need for standardization, not only of the PROM instruments, but also in procedures for analysis, interpretation and reporting PRO data. More work needs to be done to determine the degree of change that is important to patients and that is associated with increased risks of clinical events. This 'minimal clinically important difference' requires further research to determine thresholds for different PROMs, to assess consistency across trial populations, and to define standards for improvement that warrant regulatory and reimbursement approvals. PROs are a vital part of patient care and drug development, and more work should be done to ensure that these measures are both reflective of the patient experience and that they are more widely employed.
(© 2023 European Society of Cardiology.)
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Lucas, Jacqueline, Villarroel, Maria, and Cohen, Robin
- Morbidity and Mortality Weekly Report. March 3, 2023, Vol. 72 Issue 9, p244, 1 p.
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4. Patterns of failure in pediatric medulloblastoma and implications for hippocampal sparing. [2023]
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Baliga S, Adams JA, Bajaj BVM, Van Benthuysen L, Daartz J, Gallotto SL, Lewy JR, DeNunzio N, Weyman EA, Lawell MP, Palmer JD, Yeap BY, Ebb DH, Huang MS, Perry AF, MacDonald SM, Jones RM, Tarbell NJ, and Yock TI
Cancer [Cancer] 2023 Mar 01; Vol. 129 (5), pp. 764-770. Date of Electronic Publication: 2022 Dec 11.
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Humans, Child, Organ Sparing Treatments methods, Organs at Risk, Protons, Prospective Studies, Radiotherapy Planning, Computer-Assisted methods, Radiotherapy Dosage, Cranial Irradiation adverse effects, Cranial Irradiation methods, Neoplasm Recurrence, Local epidemiology, Hippocampus diagnostic imaging, Medulloblastoma radiotherapy, Brain Neoplasms radiotherapy, Brain Neoplasms secondary, Radiotherapy, Intensity-Modulated methods, and Cerebellar Neoplasms radiotherapy
- Abstract
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Background: Hippocampal avoidance (HA) has been shown to preserve cognitive function in adult patients with cancer treated with whole-brain radiation therapy for brain metastases. However, the feasibility of HA in pediatric patients with brain tumors has not been explored because of concerns of increased risk of relapse in the peri-hippocampal region. Our aim was to determine patterns of recurrence and incidence of peri-hippocampal relapse in pediatric patients with medulloblastoma (MB).
Methods and Materials: We identified pediatric patients with MB treated with protons between 2002 and 2016 and who had recurrent disease. To estimate the risk of peri-hippocampal recurrence, three hippocampal zones (HZs) were delineated corresponding to ≤5 mm (HZ-1), 6 to 10 mm (HZ-2), and >10 mm (HZ-3) distance of the recurrence from the contoured hippocampi. To determine the feasibility of HA, three standard-risk patients with MB were planned using either volumetric-modulated arc therapy (VMAT) or intensity-modulated proton therapy (IMPT) plans.
Results: Thirty-eight patients developed a recurrence at a median of 1.6 years. Of the 25 patients who had magnetic resonance imaging of the recurrence, no patients failed within the hippocampus and only two patients failed within HZ-1. The crude incidence of peri-hippocampal failure was 8%. Both HA-VMAT and HA-IMPT plans were associated with significantly reduced mean dose to the hippocampi (p < .05). HA-VMAT and HA-IMPT plans were associated with decreased percentage of the third and lateral ventricles receiving the prescription craniospinal dose of 23.4 Gy.
Conclusions: Peri-hippocampal failures are uncommon in pediatric patients with MB. Hippocampal avoidance should be evaluated in a prospective cohort of pediatric patients with MB.
Plain Language Summary: In this study, the patterns of disease recurrence in patients with a pediatric brain tumor known as medulloblastoma treated with proton radiotherapy were examined. The majority of failures occur outside of an important structure related to memory formation called the hippocampus. Hippocampal sparing radiation plans using proton radiotherapy were generated and showed that dose to the hippocampus was able to be significantly reduced. The study provides the rationale to explore hippocampal sparing in pediatric medulloblastoma in a prospective clinical trial.
(© 2022 The Authors. Cancer published by Wiley Periodicals LLC on behalf of American Cancer Society.)
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Groenewold NA, Bas-Hoogendam JM, Amod AR, Laansma MA, Van Velzen LS, Aghajani M, Hilbert K, Oh H, Salas R, Jackowski AP, Pan PM, Salum GA, Blair JR, Blair KS, Hirsch J, Pantazatos SP, Schneier FR, Talati A, Roelofs K, Volman I, Blanco-Hinojo L, Cardoner N, Pujol J, Beesdo-Baum K, Ching CRK, Thomopoulos SI, Jansen A, Kircher T, Krug A, Nenadić I, Stein F, Dannlowski U, Grotegerd D, Lemke H, Meinert S, Winter A, Erb M, Kreifelts B, Gong Q, Lui S, Zhu F, Mwangi B, Soares JC, Wu MJ, Bayram A, Canli M, Tükel R, Westenberg PM, Heeren A, Cremers HR, Hofmann D, Straube T, Doruyter AGG, Lochner C, Peterburs J, Van Tol MJ, Gur RE, Kaczkurkin AN, Larsen B, Satterthwaite TD, Filippi CA, Gold AL, Harrewijn A, Zugman A, Bülow R, Grabe HJ, Völzke H, Wittfeld K, Böhnlein J, Dohm K, Kugel H, Schrammen E, Zwanzger P, Leehr EJ, Sindermann L, Ball TM, Fonzo GA, Paulus MP, Simmons A, Stein MB, Klumpp H, Phan KL, Furmark T, Månsson KNT, Manzouri A, Avery SN, Blackford JU, Clauss JA, Feola B, Harper JC, Sylvester CM, Lueken U, Veltman DJ, Winkler AM, Jahanshad N, Pine DS, Thompson PM, Stein DJ, and Van der Wee NJA
Molecular psychiatry [Mol Psychiatry] 2023 Mar; Vol. 28 (3), pp. 1079-1089. Date of Electronic Publication: 2023 Jan 19.
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Adult, Adolescent, Humans, Magnetic Resonance Imaging methods, Brain, Anxiety, Neuroimaging methods, and Phobia, Social
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There is limited convergence in neuroimaging investigations into volumes of subcortical brain regions in social anxiety disorder (SAD). The inconsistent findings may arise from variations in methodological approaches across studies, including sample selection based on age and clinical characteristics. The ENIGMA-Anxiety Working Group initiated a global mega-analysis to determine whether differences in subcortical volumes can be detected in adults and adolescents with SAD relative to healthy controls. Volumetric data from 37 international samples with 1115 SAD patients and 2775 controls were obtained from ENIGMA-standardized protocols for image segmentation and quality assurance. Linear mixed-effects analyses were adjusted for comparisons across seven subcortical regions in each hemisphere using family-wise error (FWE)-correction. Mixed-effects d effect sizes were calculated. In the full sample, SAD patients showed smaller bilateral putamen volume than controls (left: d = -0.077, p FWE = 0.037; right: d = -0.104, p FWE = 0.001), and a significant interaction between SAD and age was found for the left putamen (r = -0.034, p FWE = 0.045). Smaller bilateral putamen volumes (left: d = -0.141, p FWE < 0.001; right: d = -0.158, p FWE < 0.001) and larger bilateral pallidum volumes (left: d = 0.129, p FWE = 0.006; right: d = 0.099, p FWE = 0.046) were detected in adult SAD patients relative to controls, but no volumetric differences were apparent in adolescent SAD patients relative to controls. Comorbid anxiety disorders and age of SAD onset were additional determinants of SAD-related volumetric differences in subcortical regions. To conclude, subtle volumetric alterations in subcortical regions in SAD were detected. Heterogeneity in age and clinical characteristics may partly explain inconsistencies in previous findings. The association between alterations in subcortical volumes and SAD illness progression deserves further investigation, especially from adolescence into adulthood.
(© 2023. The Author(s), under exclusive licence to Springer Nature Limited.)
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Dieleman E, van der Woude L, van Os R, van Bockel L, Coremans I, van Es C, De Jaeger K, Knol HP, Kolff W, Koppe F, Pomp J, Reymen B, Schinagl D, Spoelstra F, Tissing-Tan C, van der Voort van Zyp N, van der Wel A, Wijsman R, Dielwart M, Wiegman E, Damhuis R, and Belderbos J
Clinical lung cancer [Clin Lung Cancer] 2023 Mar; Vol. 24 (2), pp. 130-136. Date of Electronic Publication: 2022 Nov 25.
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Humans, Male, Aged, Infant, Neoplasm Staging, Chemoradiotherapy adverse effects, Carcinoma, Non-Small-Cell Lung drug therapy, Lung Neoplasms drug therapy, and Radiation Oncology
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Introduction: Chemoradiotherapy (CRT) is the standard of care in inoperable non-small-cell lung cancer (NSCLC) patients, favoring concurrent (cCRT) over sequential CRT (seqCRT), with adjuvant immunotherapy in responders. Elderly and frail NSCLC patients have generally been excluded from trials in the past. In elderly patients however, the higher treatment related morbidity of cCRT, may outweigh the possible lower tumor control of seqCRT. For elderly patients with locally advanced NSCLC real-world data is essential to be able to balance treatment toxicity and treatment outcome. The aim of this study is to analyze acute toxicity and 3-month mortality of curative chemoradiation (CRT) in patients with stage III NSCLC and to analyze whether cCRT for elderly stage III NSCLC patients is safe.
Methods: The Dutch Lung Cancer Audit-Radiotherapy (DLCA-R) is a national lung cancer audit that started in 2013 for patients treated with curative intent radiotherapy. All Dutch patients treated for stage III NSCLC between 2015 and 2018 with seqCRT or cCRT for (primary or recurrent) stage III lung cancer are included in this population-based study. Information was collected on patient, tumor- and treatment characteristics and the incidence and severity of acute non-hematological toxicity (CTCAE-4 version 4.03) and mortality within 3 months after the end of radiotherapy. To evaluate the association between prognostic factors and outcome (acute toxicity and mortality within 3 months), an univariable and multivariable analysis was performed. The definition of cCRT was:radiotherapy started within 30 days after the start of chemotherapy.
Results: Out of all 20 Dutch departments of radiation oncology, 19 centers participated in the registry. A total of 2942 NSCLC stage III patients were treated with CRT. Of these 67.2% (n = 1977) were treated with cCRT (median age 66 years) and 32.8% (n = 965) were treated with seqCRT (median age 69 years). Good performance status (WHO 0-1) was scored in 88.6% for patients treated with cCRT and in 71.0% in the patients treated with seqCRT. Acute nonhematological 3-month toxicity (CTCAE grade ≥3 or radiation pneumonitis grade ≥2) was scored in 21.9% of the patients treated with cCRT and in 17.7% of the patients treated with seqCRT. The univariable analysis for acute toxicity showed significantly increased toxicity for cCRT (P = .008), WHO ≥2 (P = .006), and TNM IIIC (P = .031). The multivariable analysis for acute toxicity was significant for cCRT (P = .015), WHO ≥2 (P = .001) and TNM IIIC (P = .016). The univariable analysis for 3-month mortality showed significance for seqCRT (P = .025), WHO ≥2 (P < .001), higher cumulative radiotherapy dose (P < .001), higher gross tumor volume total (P = .020) and male patients (p < .001). None of these variables reached significance in the multivariable analysis for 3-month mortality.
Conclusion: In this national lung cancer audit of inoperable NSCLC patients, 3-month toxicity was significantly higher in patients treated with cCRT (21.9% vs. 17.7% for seqCRT) higher TNM stage IIIC, and poor performance (WHO≥2) patients.The 3-months mortality was not significantly different for tested parameters. Age was not a risk factor for acute toxicity, nor 3 months mortality.
(Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.)
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Follmann D, Janes HE, Chu E, Jayashankar L, Petropoulos CJ, Serebryannyy L, Carroll R, Jean-Baptiste N, Narpala S, Lin BC, McDermott A, Novak RM, Graciaa DS, Rolsma S, Magaret CA, Doria-Rose N, Corey L, Neuzil KM, Pajon R, Miller JM, Donis RO, Koup RA, Baden LR, and El Sahly HM
Open forum infectious diseases [Open Forum Infect Dis] 2023 Feb 13; Vol. 10 (3), pp. ofad069. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).
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Background: Hybrid immunity is associated with more durable protection against coronavirus disease 2019 (COVID-19). We describe the antibody responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated and unvaccinated individuals.
Methods: The 55 vaccine arm COVID-19 cases diagnosed during the blinded phase of the Coronavirus Efficacy trial were matched with 55 placebo arm COVID-19 cases. Pseudovirus neutralizing antibody (nAb) activity to the ancestral strain and binding antibody (bAb) responses to nucleocapsid and spike antigens (ancestral and variants of concern [VOCs]) were assessed on disease day 1 (DD1) and 28 days later (DD29).
Results: The primary analysis set was 46 vaccine cases and 49 placebo cases with COVID-19 at least 57 days post-first dose. For vaccine group cases, there was a 1.88-fold rise in ancestral antispike bAbs 1 month post-disease onset, although 47% had no increase. The vaccine-to-placebo geometric mean ratios for DD29 antispike and antinucleocapsid bAbs were 6.9 and 0.04, respectively. DD29 mean bAb levels were higher for vaccine vs placebo cases for all VOCs. DD1 nasal viral load positively correlated with bAb levels in the vaccine group.
Conclusions: Following COVID-19, vaccinated participants had higher levels and greater breadth of antispike bAbs and higher nAb titers than unvaccinated participants. These were largely attributable to the primary immunization series.
Competing Interests: Potential conflicts of interest. R.M.N. receives support from Moderna. J.M.M. and R.P. are employed by Moderna Tx, Inc., and have stock and/or stock options in Moderna Tx, Inc. All other authors report no potential conflicts.
(Published by Oxford University Press on behalf of Infectious Diseases Society of America 2023.)
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Butcher SC, Vos JL, Fortuni F, Galloo X, Liem SIE, Bax JJ, Delgado V, Vonk MC, van Leuven SI, Snoeren M, El Messaoudi S, de Vries-Bouwstra JK, Nijveldt R, and Ajmone Marsan N
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2023 Feb 06; Vol. 62 (SI), pp. SI20-SI31.
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Female, Humans, Male, Contrast Media, Gadolinium, Magnetic Resonance Imaging, Cine, Magnetic Resonance Spectroscopy, Predictive Value of Tests, Prognosis, Stroke Volume, Ventricular Function, Left, Middle Aged, Heart Failure, Scleroderma, Systemic complications, and Scleroderma, Systemic diagnostic imaging
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Objective: This study aimed to determine whether lower values of feature-tracking cardiovascular magnetic resonance (CMR)-derived left atrial reservoir strain (LARS) and impaired left ventricular (LV) global longitudinal strain (GLS) were associated with the presence of symptoms and long-term prognosis in patients with SSc.
Methods: A total of 100 patients {54 [interquartile range (IQR) 46-64] years, 42% male} with SSc who underwent CMR imaging at two tertiary referral centres were included. All patients underwent analysis of LARS and LV GLS using feature-tracking on CMR and were followed-up for the occurrence of all-cause mortality.
Results: The median LV GLS was -21.8% and the median LARS was 36%. On multivariable logistic regression, LARS [odds ratio (OR) 0.964 per %, 95% CI 0.929, 0.998, P = 0.049] was independently associated with New York Heart Association (NYHA) class II-IV heart failure symptoms. Over a median follow-up of 37 (21-62) months, a total of 24 (24%) patients died. Univariable Cox regression analysis demonstrated that LARS [hazard ratio (HR) 0.94 per 1%, 95% CI 0.91, 0.97, P < 0.0001) and LV GLS (HR 1.10 per %, 95% CI 1.03, 1.17, P = 0.005) were associated with all-cause mortality, while LV ejection fraction was not. Likelihood ratio tests demonstrated that LARS provided incremental value over prognostically important clinical and imaging parameters, including late gadolinium enhancement.
Conclusion: In patients with SSc, LARS was independently associated with the presence of NYHA class II-IV heart failure symptoms. Although both LARS and LV GLS were associated with all-cause mortality, only LARS provided incremental value over all evaluated variables known to be prognostically important in patients with SSc.
(© The Author(s) 2022. Published by Oxford University Press on behalf of the British Society for Rheumatology.)
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Zeidan AM, Borate U, Pollyea DA, Brunner AM, Roncolato F, Garcia JS, Filshie R, Odenike O, Watson AM, Krishnadasan R, Bajel A, Naqvi K, Zha J, Cheng WH, Zhou Y, Hoffman D, Harb JG, Potluri J, and Garcia-Manero G
American journal of hematology [Am J Hematol] 2023 Feb; Vol. 98 (2), pp. 272-281. Date of Electronic Publication: 2022 Nov 10.
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Aged, Humans, Male, Azacitidine therapeutic use, Leukemia, Myeloid, Acute drug therapy, Neutropenia chemically induced, Sulfonamides, Treatment Outcome, Female, Antineoplastic Combined Chemotherapy Protocols adverse effects, and Myelodysplastic Syndromes drug therapy
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Patients with relapsed/refractory (R/R) higher-risk myelodysplastic syndromes (MDS) have a dismal median overall survival (OS) after failing hypomethylating agent (HMA) treatment. There is no standard of care for patients after HMA therapy failure; hence, there is a critical need for effective therapeutic strategies. Herein, we present the safety and efficacy of venetoclax + azacitidine in patients with R/R MDS. This phase 1b, open-label, multicenter study enrolled patients ≥18 years. Patients were treated with escalating doses of oral venetoclax: 100, 200, or 400 mg daily for 14 days every 28-day cycle. Azacitidine was administered on Days 1-7 every cycle at 75 mg/m 2 /day intravenously/subcutaneously. Responses were assessed per modified 2006 International Working Group (IWG) criteria. Forty-four patients (male 86%, median age 74 years) received venetoclax + azacitidine treatment. Median follow-up was 21.2 months. Hematological adverse events of Grade ≥ 3 included febrile neutropenia (34%), thrombocytopenia (32%), neutropenia (27%), and anemia (18%). Pneumonia (23%) was the most common Grade ≥ 3 infection. Marrow responses were seen including complete remission (CR, n = 3, 7%) and marrow CR (mCR, n = 14, 32%); 36% (16/44) achieved transfusion independence (TI) for RBCs and/or platelets, and 43% (6/14) with mCR achieved hematological improvement (HI). The median time to CR/mCR was 1.2 months, and the median duration of response for CR + mCR was 8.6 months. Median OS was 12.6 months. Venetoclax + azacitidine shows activity in patients with R/R MDS following prior HMA therapy failure and provides clinically meaningful benefits, including HI and TI, and encouraging OS.
(© 2022 The Authors. American Journal of Hematology published by Wiley Periodicals LLC.)
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Cruzado-Quiñones J, Huibregtse RC, and Jordan AO
Journal of correctional health care : the official journal of the National Commission on Correctional Health Care [J Correct Health Care] 2023 Feb; Vol. 29 (1), pp. 19-26. Date of Electronic Publication: 2023 Jan 25.
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Female, Humans, New York City, Puerto Rico, Transgender Persons, Male, Hispanic or Latino, and Health Services for Transgender Persons
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Transitional Care Coordination is an evidence-informed model program developed by New York City Correctional Health Services as a Health Resources and Services Administration Special Projects of National Significance Correctional Health Linkage Intervention. Using implementation science under this and subsequent demonstration projects, interventions were adapted and enhanced to address the transitional needs of people of Puerto Rican ancestry and to expand the network of care across the islands of Puerto Rico. These interventions were informed, in part, by a transnational trans woman of color of Puerto Rican ancestry living with HIV. A socioecological model framework and case study are used to illustrate how evidence-informed interventions are developed and adapted to address the needs of those served.
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Alasfar S, Chiang TP, Snyder AJ, Ou MT, Boyarsky BJ, Abedon AT, Alejo JL, Cook S, Cochran W, Brigham E, Parker AM, Garonzik-Wang J, Massie AB, Brennan DC, Vannorsdall T, Segev DL, and Avery RK
Transplantation [Transplantation] 2023 Jan 01; Vol. 107 (1), pp. 181-191. Date of Electronic Publication: 2022 Sep 19.
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Humans, Self Report, SARS-CoV-2, Quality of Life, COVID-19 Testing, Transplant Recipients, Cough, Pain, COVID-19 epidemiology, and Organ Transplantation adverse effects
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Background: Postacute sequelae of SARS-CoV-2 infection (PASC) is an increasingly recognized phenomenon and manifested by long-lasting cognitive, mental, and physical symptoms beyond the acute infection period. We aimed to estimate the frequency of PASC symptoms in solid organ transplant (SOT) recipients and compared their frequency between those with SARS-CoV-2 infection requiring hospitalization and those who did not require hospitalization.
Methods: A survey consisting of 7 standardized questionnaires was administered to 111 SOT recipients with history of SARS-CoV-2 infection diagnosed >4 wk before survey administration.
Results: Median (interquartile range) time from SARS-CoV-2 diagnosis was 167 d (138-221). Hospitalization for SARS-CoV-2 infection was reported in 33 (30%) participants. Symptoms after the COVID episode were perceived as following: significant trauma (53%), cognitive decline (50%), fatigue (41%), depression (36%), breathing problems (35%), anxiety (23%), dysgeusia (22%), dysosmia (21%), and pain (19%). Hospitalized patients had poorer median scores in cognition (Quick Dementia Rating System survey score: 2.0 versus 0.5, P = 0.02), quality of life (Health-related Quality of Life survey: 2.0 versus 1.0, P = 0.015), physical health (Global physical health scale: 10.0 versus 11.0, P = 0.005), respiratory status (Breathlessness, Cough and Sputum Scale: 1.0 versus 0.0, P = 0.035), and pain (Pain score: 3 versus 0 out of 10, P = 0.003). Among patients with infection >6 mo prior, some symptoms were still present as following: abnormal breathing (42%), cough (40%), dysosmia (29%), and dysgeusia (34%).
Conclusions: SOT recipients reported a high frequency of PASC symptoms. Multidisciplinary approach is needed to care for these patients beyond the acute phase.
(Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
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Mitchell J, Chiang TP, Alejo JL, Kim JD, Chang A, Abedon AT, Avery RK, Tobian AAR, Levan ML, Warren DS, Garonzik-Wang JM, Segev DL, Massie AB, and Werbel WA
Clinical transplantation [Clin Transplant] 2023 Jan; Vol. 37 (1), pp. e14868. Date of Electronic Publication: 2022 Dec 07.
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Humans, COVID-19 Vaccines, Kinetics, SARS-CoV-2, Antibodies, Transplant Recipients, Antibodies, Viral, COVID-19 epidemiology, COVID-19 prevention control, and Organ Transplantation
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Jenewein, Erin C., Cotter, Susan, Roberts, Tawna, Kulp, Marjean, Mitchell, G. Lynn, Jones-Jordan, Lisa A., Chen, Angela M., Hopkins, Kristine, Huang, Kristine, Amster, Deborah, Fecho, Gregory, Tyler, Julie, Meiyeppen, Shivakhaami, Scheiman, Mitchell, Scheiman, Mitchell, Cooper, Jeffrey, Schulman, Erica, Hamian, Kimberly, Iacono, Danielle, Larson, Steven, Leung, Valerie, Meeder, Sara, Ramos, Elaine, Ritter, Steven, Steiner, Audra, Stormann, Alexandria, Vricella, Marilyn, Zhu, Xiaoying, Tamkins, Susanna, Aguilera, Naomi, Brafman, Elliot, Capo, Hilda, Cavuoto, Kara, Crespo, Isaura, Dowling, Monica, Draskovic, Kristie, Farag, Miriam, Fischer, Vicky, Grace, Sara, Gutierrez, Ailen, Manchola-Orozco, Carolina, Martinez, Maria, McKeown, Craig, Osigian, Carla, Pham, Tuyet-Suong, Small, Leslie, Townsend, Natalie, Gallaway, Michael, Boas, Mark, Calvert, Christine, Franz, Tara, Gerrouge, Amanda, Hayden, Donna, Margolies, Zachary, Myung, Jenny, Pollack, Karen, Shoge, Ruth, Tang, Andrew, Tannen, Noah, Trieu, Lynn, Trujillo, Luis, Buckland, Michelle, Ellis, Allison, Fogt, Jennifer, McDaniel, Catherine, McGann, Taylor, Morrison, Ann, Mulvihill, Shane, Peiffer, Adam, Plaumann, Maureen, Pierce, Gil, Preston, Julie, Reuter, Kathleen, Stevens, Nancy, Teeny, Jake, Toole, Andrew, Widmer, Douglas, Zimmerman, Aaron, Barnhardt, Carmen, Borsting, Eric, Chu, Raymond, Parker, Susan, Retnasothie, Dashaini, Wu, Judith, Hertle, Richard, Clark, Penny, Culp, Kelly, Fraley, Kathy, Grant, Drusilla, Hanna, Nancy, Knox, Stephanie, Lawhon, William, Li, Lan, Mitcheff, Sarah, Ricker, Isabel, Solis, Casandra, Wall, Palak, Zaczyk, Samantha, Marsh-Tootle, Wendy, Bowen, Michelle, Call, Terri, Domnanovich, Kristy, Frazier, Marcela, Guyette, Nicole, Hayes, Oakley, Houser, John, Lee, Sarah, Montejo, Jenifer, Oechslin, Tamara, Turner, Candace, Weise, Katherine, Coulter, Rachel, Bade, Annette, Bansal, Surbhi, Falco, Laura, Green, Katherine, Irizarry, Gabriela, Jhajj, Jasleen, Patterson, Nicole, Rodena, Jacqueline, Tea, Yin, Weiss, Dana, Zakaib, Lauren, Lorenzana, Ingryd, Meza, Yesena, Mann, Ryan, Quezada, Mariana, Rein, Scott, Rudaitis, Indre, Stepleton, Susan, Wajs, Beata, Redford, Maryann, Hertle, Richard, Redford, Maryann, Denton, Carolyn, Arnold, Eugene, Borsting, Eric, Chase, Christopher, Denton, Carolyn, Wee, Sharyl, Dahl-Leonard, Katlynn, Powers, Kenneth, Alaniz, Amber, Diener-West, Marie, Good, William V., Grisham, David, Kratochvil, Christopher J., Revicki, Dennis, Wanzek, Jeanne, Pollack, Karen, Abraham, Mustafa, Dangelo, Julianne, Hegedus, Jordan, Jones, Ian, Junglas, Alexander, Lee, Jihyun, Nettles, Jadin, Mitchell, Curtis, Osman, Mawada, Scott-Tibbs, Gloria, Sinnott, Loraine, Teasley, Chloe, Vang, Victor, and Varghese, Robin
- Ophthalmic and Physiological Optics. January, 2023, Vol. 43 Issue 1, p105, 11 p.
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Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Yousri NA, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Hwu CM, Hung YJ, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Ruotsalainen SE, Daw E, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Vazquez-Moreno M, Feitosa MF, Wojczynski MK, Wang Z, Preuss MH, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Tsao NL, Verma A, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Frank M, Schmidt B, Smyth LJ, Cañadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kähönen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Bayyana S, Stringham HM, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Prasad G, Lorés-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Nardone GG, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas MP, Vaccargiu S, van der Most PJ, Pitkänen N, Cade BE, van der Laan SW, Chitrala KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikäinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Liang J, Tang H, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jäger S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Kähönen M, Pérusse L, Bouchard C, Tönjes A, Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellström D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Zimmermann ME, Völzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Kardia SLR, Peyser PA, Kato N, Schulze MB, Girotto G, Böger CA, Jung B, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Tusié-Luna T, Aguilar-Salinas CA, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Hunt SC, Walker M, Koistinen HA, Chandak GR, Mercader JM, Costanzo MC, Jang D, Burtt NP, Villalpando CG, Orozco L, Fornage M, Tai E, van Dam RM, Lehtimäki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jöckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Qu J, Hishigaki H, Lin X, März W, Gudnason V, Tardif JC, Lettre G, Hart LM', Elders PJM, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP, Rotimi CN, Christensen K, Ripatti S, Widén E, Hakonarson H, Grant SFA, Kiemeney LALM, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, Männikkö M, Jarvelin MR, Kutalik Z, Francesco C, Mook-Kanamori DO, van Dijk KW, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Chuang LM, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, Willemsen AHM, Cupples L, van Meurs JBJ, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A, Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, Åsvold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen Y, Ho YL, Lynch JA, Rader DJ, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson PWF, Frayling TM, Hirschhorn JN, Kathiresan S, Mohlke KL, Sun YV, Morris AP, Boehnke M, Brown CD, Natarajan P, Deloukas P, Willer CJ, Assimes TL, and Peloso GM
Genome biology [Genome Biol] 2022 Dec 27; Vol. 23 (1), pp. 268. Date of Electronic Publication: 2022 Dec 27.
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Humans, Sex Characteristics, Phenotype, Lipids genetics, Polymorphism, Single Nucleotide, Genetic Pleiotropy, Genome-Wide Association Study, and Genetic Predisposition to Disease
- Abstract
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Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery.
Results: To expand our understanding of the underlying biological pathways and mechanisms controlling blood lipid levels, we leverage a large multi-ancestry meta-analysis (N = 1,654,960) of blood lipids to prioritize putative causal genes for 2286 lipid associations using six gene prediction approaches. Using phenome-wide association (PheWAS) scans, we identify relationships of genetically predicted lipid levels to other diseases and conditions. We confirm known pleiotropic associations with cardiovascular phenotypes and determine novel associations, notably with cholelithiasis risk. We perform sex-stratified GWAS meta-analysis of lipid levels and show that 3-5% of autosomal lipid-associated loci demonstrate sex-biased effects. Finally, we report 21 novel lipid loci identified on the X chromosome. Many of the sex-biased autosomal and X chromosome lipid loci show pleiotropic associations with sex hormones, emphasizing the role of hormone regulation in lipid metabolism.
Conclusions: Taken together, our findings provide insights into the biological mechanisms through which associated variants lead to altered lipid levels and potentially cardiovascular disease risk.
(© 2022. The Author(s).)
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Saunders, Gretchen R. B., Wang, Xingyan, Chen, Fang, Jang, Seon-Kyeong, Liu, Mengzhen, Wang, Chen, Gao, Shuang, Jiang, Yu, Khunsriraksakul, Chachrit, Otto, Jacqueline M., Addison, Clifton, Akiyama, Masato, Albert, Christine M., Aliev, Fazil, Alonso, Alvaro, Arnett, Donna K., Ashley-Koch, Allison E., Ashrani, Aneel A., Barnes, Kathleen C., Barr, R. Graham, Bartz, Traci M., Becker, Diane M., Bielak, Lawrence F., Benjamin, Emelia J., Bis, Joshua C., Bjornsdottir, Gyda, Blangero, John, Bleecker, Eugene R., Boardman, Jason D., Boerwinkle, Eric, Boomsma, Dorret I., Boorgula, Meher Preethi, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Chasman, Daniel I., Chavan, Sameer, Chen, Yii-Der Ida, Chen, Zhengming, Cheng, Iona, Cho, Michael H., Choquet, Hélène, Cole, John W., Cornelis, Marilyn C., Cucca, Francesco, Curran, Joanne E., de Andrade, Mariza, Dick, Danielle M., Docherty, Anna R., Duggirala, Ravindranath, Eaton, Charles B., Ehringer, Marissa A., Esko, Tõnu, Faul, Jessica D., Fernandes Silva, Lilian, Fiorillo, Edoardo, Fornage, Myriam, Freedman, Barry I., Gabrielsen, Maiken E., Garrett, Melanie E., Gharib, Sina A., Gieger, Christian, Gillespie, Nathan, Glahn, David C., Gordon, Scott D., Gu, Charles C., Gu, Dongfeng, Gudbjartsson, Daniel F., Guo, Xiuqing, Haessler, Jeffrey, Hall, Michael E., Haller, Toomas, Harris, Kathleen Mullan, He, Jiang, Herd, Pamela, Hewitt, John K., Hickie, Ian, Hidalgo, Bertha, Hokanson, John E., Hopfer, Christian, Hottenga, JoukeJan, Hou, Lifang, Huang, Hongyan, Hung, Yi-Jen, Hunter, David J., Hveem, Kristian, Hwang, Shih-Jen, Hwu, Chii-Min, Iacono, William, Irvin, Marguerite R., Jee, Yon Ho, Johnson, Eric O., Joo, Yoonjung Y., Jorgenson, Eric, Justice, Anne E., Kamatani, Yoichiro, Kaplan, Robert C., Kaprio, Jaakko, Kardia, Sharon L. R., Keller, Matthew C., Kelly, Tanika N., Kooperberg, Charles, Korhonen, Tellervo, Kraft, Peter, Krauter, Kenneth, Kuusisto, Johanna, Laakso, Markku, Lasky-Su, Jessica, Lee, Wen-Jane, Lee, James J., Levy, Daniel, Li, Liming, Li, Kevin, Li, Yuqing, Lin, Kuang, Lind, Penelope A., Liu, Chunyu, Lloyd-Jones, Donald M., Lutz, Sharon M., Ma, Jiantao, Mägi, Reedik, Manichaikul, Ani, Martin, Nicholas G., Mathur, Ravi, Matoba, Nana, McArdle, Patrick F., McGue, Matt, McQueen, Matthew B., Medland, Sarah E., Metspalu, Andres, Meyers, Deborah A., Millwood, Iona Y., Mitchell, Braxton D., Mohlke, Karen L., Moll, Matthew, Montasser, May E., Morrison, Alanna C., Mulas, Antonella, Nielsen, Jonas B., North, Kari E., Oelsner, Elizabeth C., Okada, Yukinori, Orrù, Valeria, Palmer, Nicholette D., Palviainen, Teemu, Pandit, Anita, Park, S. Lani, Peters, Ulrike, Peters, Annette, Peyser, Patricia A., Polderman, Tinca J. C., Rafaels, Nicholas, Redline, Susan, Reed, Robert M., Reiner, Alex P., Rice, John P., Rich, Stephen S., Richmond, Nicole E., Roan, Carol, Rotter, Jerome I., Rueschman, Michael N., Runarsdottir, Valgerdur, Saccone, Nancy L., Schwartz, David A., Shadyab, Aladdin H., Shi, Jingchunzi, Shringarpure, Suyash S., Sicinski, Kamil, Skogholt, Anne Heidi, Smith, Jennifer A., Smith, Nicholas L., Sotoodehnia, Nona, Stallings, Michael C., Stefansson, Hreinn, Stefansson, Kari, Stitzel, Jerry A., Sun, Xiao, Syed, Moin, Tal-Singer, Ruth, Taylor, Amy E., Taylor, Kent D., Telen, Marilyn J., Thai, Khanh K., Tiwari, Hemant, Turman, Constance, Tyrfingsson, Thorarinn, Wall, Tamara L., Walters, Robin G., Weir, David R., Weiss, Scott T., White, Wendy B., Whitfield, John B., Wiggins, Kerri L., Willemsen, Gonneke, Willer, Cristen J., Winsvold, Bendik S., Xu, Huichun, Yanek, Lisa R., Yin, Jie, Young, Kristin L., Young, Kendra A., Yu, Bing, Zhao, Wei, Zhou, Wei, Zöllner, Sebastian, Zuccolo, Luisa, Batini, Chiara, Bergen, Andrew W., Bierut, Laura J., David, Sean P., Gagliano Taliun, Sarah A., Hancock, Dana B., Jiang, Bibo, Munafò, Marcus R., Thorgeirsson, Thorgeir E., Liu, Dajiang J., and Vrieze, Scott
- Nature; December 2022, Vol. 612 Issue: 7941 p720-724, 5p
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Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide deaths, respectively, due largely to broad increased risk for disease and injury1–4. These substances are used across the globe, yet genome-wide association studies have focused largely on individuals of European ancestries5. Here we leveraged global genetic diversity across 3.4 million individuals from four major clines of global ancestry (approximately 21% non-European) to power the discovery and fine-mapping of genomic loci associated with tobacco and alcohol use, to inform function of these loci via ancestry-aware transcriptome-wide association studies, and to evaluate the genetic architecture and predictive power of polygenic risk within and across populations. We found that increases in sample size and genetic diversity improved locus identification and fine-mapping resolution, and that a large majority of the 3,823 associated variants (from 2,143 loci) showed consistent effect sizes across ancestry dimensions. However, polygenic risk scores developed in one ancestry performed poorly in others, highlighting the continued need to increase sample sizes of diverse ancestries to realize any potential benefit of polygenic prediction.
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Vos JL, Leiner T, van Dijk APJ, Pedrizzetti G, Alenezi F, Rodwell L, van der Wegen CTPM, Post MC, Driessen MMP, and Nijveldt R
European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2022 Dec 19; Vol. 24 (1), pp. 78-87.
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Humans, Ventricular Pressure, Cross-Sectional Studies, Heart Ventricles, Ventricular Function, Left, Stroke Volume, Magnetic Resonance Spectroscopy, Hypertension, Pulmonary, and Ventricular Dysfunction, Left
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Aims: Precapillary pulmonary hypertension (pPH) affects left ventricular (LV) function by ventricular interdependence. Since LV ejection fraction (EF) is commonly preserved, LV dysfunction should be assessed with more sensitive techniques. Left atrial (LA) strain and estimation of LV intraventricular pressure gradients (IVPG) may be valuable in detecting subtle changes in LV mechanics; however, the value of these techniques in pPH is unknown. Therefore, the aim of our study is to evaluate LA strain and LV-IVPGs from cardiovascular magnetic resonance (CMR) cines in pPH patients.
Methods and Results: In this cross-sectional study, 31 pPH patients and 22 healthy volunteers underwent CMR imaging. Feature-tracking LA strain was measured on four- and two-chamber cines. LV-IVPGs (from apex-base) are computed from a formulation using the myocardial movement and velocity of the reconstructed 3D-LV (derived from long-axis cines using feature-tracking). Systolic function, both LV EF and systolic ejection IVPG, was preserved in pPH patients. Compared to healthy volunteers, diastolic function was impaired in pPH patients, depicted by (i) lower LA reservoir (36 ± 7% vs. 26 ± 9%, P < 0.001) and conduit strain (26 ± 6% vs. 15 ± 8%, P < 0.001) and (ii) impaired diastolic suction (-9.1 ± 3.0 vs. ‒6.4 ± 4.4, P = 0.02) and E-wave decelerative IVPG (8.9 ± 2.6 vs. 5.7 ± 3.1, P < 0.001). Additionally, 11 pPH patients (35%) showed reversal of IVPG at systolic-diastolic transition compared to none of the healthy volunteers (P = 0.002).
Conclusions: pPH impacts LV function by altering diastolic function, demonstrated by an impairment of LA phasic function and LV-IVPG analysis. These parameters could therefore potentially be used as early markers for LV functional decline in pPH patients.
Competing Interests: Conflict of interest: none declared.
(© Crown copyright 2022.)
17. Circulating adipose tissue proteins involved in atrial fibrillation: An explorative scoping review. [2022]
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Meulendijks ER, Krul SPJ, Baalman SW, de Vries TAC, Wesselink R, Ernault AC, Kawasaki M, Al-Shama R, Neefs J, Limpens J, and de Groot JR
Trends in cardiovascular medicine [Trends Cardiovasc Med] 2022 Dec 17. Date of Electronic Publication: 2022 Dec 17.
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Obesity increases the risk of atrial fibrillation (AF), potentially through proteins secreted by adipose tissue (AT) that affect atrial electrical and structural remodeling. We aim to give a comprehensive overview of circulating AT proteins involved in inflammation and fibrosis, that are associated with prevalent AF (paroxysmal or persistent) and the risk on developing new-onset AF. These include adipokines, defined as proteins enriched in AT as adiponectin, but also proteins less specific to AT. We systematically performed an explorative search for studies reporting associations between proteins secreted from cells residing in the AT and AF, and additionally assessed the effect of obesity on these proteins by a secondary search. The AT proteins involved in inflammation were mostly increased in patients with prevalent and new-onset AF, and with obesity, while the AT enriched adipokines were mostly not associated with AF. This review provides insight into circulating adipose tissue proteins involved in AF substrate formation.
(Copyright © 2022. Published by Elsevier Inc.)
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18. PART is part of SNAP‐MCI. [2022]
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Wisse, Laura EM, Xie, Long, Lyu, Xueying, Das, Sandhitsu R., de Flores, Robin, Lane, Jacqueline, Yushkevich, Paul A., Wolk, David A., and Initiative, Disease Neuroimaging
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2022 Supplement 6, Vol. 18 Issue 6, p1-4, 4p
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Background: Mild Cognitive Impairment with Suspected non‐Alzheimer's Pathophysiology (SNAP‐MCI) represents a group of patients with Alzheimer's disease (AD) like neurodegeneration without beta‐amyloid pathology. While this group likely has a heterogeneous etiology, tau pathology, as in Primary Age‐Related Tauopathy (PART), has been hypothesized to play a major role. We investigate tau positron emission tomography (PET) uptake in the medial temporal lobe (MTL) in SNAP‐MCI and the association of MTL Tau‐PET uptake with structural measures and delayed recall in beta‐amyloid negative (A‐) MCI patients. Method: 237 MCI patients and 301 A‐ controls with available beta‐amyloid and tau PET and magnetic resonance images (within 200 days) were included. Baseline hippocampal volume and entorhinal cortex (ERC) and Brodmann areas (BA)35 thickness were obtained using an in‐house developed pipeline and annualized atrophy rates were estimated in an unbiased fashion using follow‐up MRIs within 4.5 years. Βeta‐amyloid status (A+/‐) was determined by a standard cut‐off (Florbetapir: 1.11; Florbetaben: 1.08) and neurodegeneration status (N+/‐) by hippocampal volumes, corrected for intracranial volume, using the 90th percentile of A+ AD patients as the cut‐off. Tau‐PET standardized uptake value ratio (SUVR) in the ERC/BA35 was calculated. A composite z‐score of delayed recall at baseline and change over 2 years was obtained. Result: SNAP‐MCI had significantly higher ERC/BA35 Tau‐PET SUVR than A‐ controls (Table 1, corrected for age) and qualitatively higher than A‐N‐ MCI (p=0.10). ERC/BA35 Tau‐PET SUVR in A‐N‐ MCI was not significantly different from A‐ controls. In A‐ MCI patients, ERC/BA35 Tau‐PET SUVR was significantly associated with BA35 thickness and hippocampal, ERC and BA35 atrophy rates, corrected for beta‐amyloid PET SUVR (Table 2; Figure 1). MTL structural measures, but not ERC/BA35 Tau‐PET SUVR, were associated with cross‐sectional and longitudinal delayed recall measures (Table 3; Figure 2). Conclusion: SNAP‐MCI had elevated ERC/BA35 Tau‐PET SUVR and ERC/BA35 Tau‐PET SUVR was associated with MTL structural measures in A‐ MCI patients. This indicates that tau pathology might be an important driver of neurodegeneration in the absence of beta‐amyloid pathology, supporting the notion that PART contributes to SNAP‐MCI. Additionally, MTL structure was associated with memory performance, consistent with SNAP not being a benign condition. [ABSTRACT FROM AUTHOR]
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Yang, David, Best, John R., Chambers, Colleen, Feldman, Howard H., Pettersen, Jacqueline A, Henri‐Bhargava, Alexander, Lee, Philip E, Nygaard, Haakon B., Funnell, Clark R, Foti, Dean J, Hsiung, Ging‐Yuek Robin, and DeMarco, Mari L.
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2022 Supplement 6, Vol. 18 Issue 6, p1-2, 2p
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Background: While previous studies have demonstrated the effect of Alzheimer's disease (AD) CSF testing in changing diagnosis, we lack an understanding of how this testing affects clinical management. Therefore, we assessed changes in clinical management associated with AD CSF biomarker testing when ordered as part of routine clinical management. Method: The 'Investigating the Impact of Alzheimer's Disease Diagnostics in British Columbia' (IMPACT‐AD BC) study (NCT05002699) is a longitudinal study examining the impact of AD CSF testing on clinical management, personal utility and health care economics in British Columbia, Canada. After AD CSF testing was ordered as part of routine care (where the clinical scenario met the appropriate use criteria), the patient and their physician were eligible to participate in the study. The primary outcome was the change in management (pre‐ v. post‐biomarker results) in a composite measure including 1) AD drug therapy, 2) other relevant drug therapy, 3) other diagnostic procedures, and 4) referral or counselling. Result: Participants (n = 129) had a median age of 63 (IQR:58‐68); 49% were female. Cognitive impairment at baseline consisted of 7% with subjective cognitive impairment, 53% with mild cognitive impairment, and 40% with dementia. CSF biomarker profiles were consistent with an amyloid‐beta pathology (i.e., A+) in 72% of cases. Changes in clinical management because of testing occurred in 83% of cases including: referrals and counseling (57%), imaging (47%) and other diagnostic procedures (e.g., neuropsychological testing) (42%), and use of AD drug therapies (40%). For those with a non‐AD pre‐biomarkers diagnosis, 42% were changed to AD post‐biomarkers; for those with an AD pre‐biomarkers diagnosis, 18% were changed to non‐AD post‐biomarkers. Conclusion: This study has revealed substantial changes in clinical management as a direct result of AD CSF biomarker testing in routine care. An understanding of the implications of biomarker testing will in turn help us: improve appropriate utilization, understand the broader impacts on persons living with dementia and on the health care system, and prepare for expanded use of this testing with the availability of disease‐modifying therapeutics. [ABSTRACT FROM AUTHOR]
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20. Reply: Further Insights Into the Prognostic Value of Left Atrial Strain in Dilated Cardiomyopathy? [2022]
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Raafs AG, Henkens MTHM, Vos JL, Nijveldt R, and Verdonschot JAJ
JACC. Cardiovascular imaging [JACC Cardiovasc Imaging] 2022 Dec; Vol. 15 (12), pp. 2156-2157.
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Humans, Prognosis, Predictive Value of Tests, Cardiomyopathy, Dilated diagnostic imaging, Atrial Fibrillation, and Atrial Appendage
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Makhlin I, McAndrew NP, Wileyto EP, Clark AS, Holmes R, Bottalico LN, Mesaros C, Blair IA, Jeschke GR, Fox KR, Domchek SM, Matro JM, Bradbury AR, Feldman MD, Hexner EO, Bromberg JF, and DeMichele A
NPJ breast cancer [NPJ Breast Cancer] 2022 Nov 11; Vol. 8 (1), pp. 122. Date of Electronic Publication: 2022 Nov 11.
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Circulating IL-6, an activator of JAK/STAT signaling, is associated with poor prognosis and aromatase inhibitor (AI) resistance in hormone-receptor positive (HR+) breast cancer. Here we report the results of a phase 2 single-arm Simon 2-stage trial combining Ruxolitinib, an oral selective inhibitor of JAK1/2, with exemestane, a steroidal AI, in patients with HR+ metastatic breast cancer (MBC) after progression on non-steroidal AI (NSAI). Safety and efficacy were primary objectives, and analysis of inflammatory markers as predictors of response was a key secondary objective. Twenty-five subjects enrolled. The combination of ruxolitinib and exemestane was safe, though anemia requiring transfusion in 5/15 (33%) at the 25 mg dose in stage 1 led to a reduction to 15 mg twice daily in stage 2 (with no additional transfusions). Clinical benefit rate (CBR) in the overall study population was 24% (95% CI 9.4-45.1); 6/25 patients demonstrated stable disease for ≥6 months. Median progression-free survival was 2.8 months (95% CI 2.6-3.9). Exploratory biomarkers revealed high levels of systemic inflammation and 60% harbored a high-risk IL-6 genotype. Pharmacodynamics demonstrated modest on-target inhibition of phosphorylated-STAT3 by ruxolitinib at a tolerable dose. Thus, ruxolitinib combined with exemestane at a tolerable dose was safe but minimally active in AI-resistant tumors of patients with high levels of systemic inflammation. These findings highlight the need for more potent and specific therapies targeting inflammation in MBC.
(© 2022. The Author(s).)
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Petrovic B, O'Brien MA, Liddy C, Afkham A, McGee SF, Morgan SC, Segal R, Bender JL, Sussman J, Urquhart R, Fitch M, Schneider ND, and Grunfeld E
Current oncology (Toronto, Ont.) [Curr Oncol] 2022 Nov 03; Vol. 29 (11), pp. 8401-8414. Date of Electronic Publication: 2022 Nov 03.
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Male, Humans, Qualitative Research, Communication, Internet, Health Personnel, and Neoplasms
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Previous research has identified communication and care coordination problems for patients with cancer. Healthcare providers (HCPs) have reported communication issues due to the incompatibility of electronic medical records (EMR) software and not being consistently copied on patient reports. We evaluated an asynchronous web-based communication system ("eOncoNote") for primary care providers and cancer specialists to improve cancer care coordination. The objectives were to examine patients' perceptions of the role of eOncoNote in their healthcare, and HCPs' experiences of implementing eOncoNote. Qualitative interviews were conducted with patients with breast and prostate cancer, primary care providers, and cancer specialists. Eighteen patients and fourteen HCPs participated. Six themes were identified from the patient interviews focusing on HCP and patient roles related to care coordination and patient awareness of communication among their HCPs. Four themes were identified from HCP interviews related to the context of care coordination and experience with eOncoNote. Both patients and HCPs described the important role patients and caregivers play in care coordination. The results show that patients were often unaware of the communication between their HCPs and assumed they were communicating. HCPs encountered challenges incorporating eOncoNote into their workflow.
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Vaughn J, Cunningham R, Schroeder LH, Waddill C, Peterson MJ, Gambacorta MR, and Sims S
Nursing forum [Nurs Forum] 2022 Nov; Vol. 57 (6), pp. 1373-1380. Date of Electronic Publication: 2022 Oct 29.
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Humans, Interprofessional Relations, Interprofessional Education, Learning, Attitude of Health Personnel, Patient Care Team, Students, Nursing, and Sports
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Background: The purpose of this article is to describe the development, implementation, and evaluation of a Simulation Interprofessional Education (Sim-IPE) activity for healthcare students from different disciplines (athletic training [AT] and nursing). The objective for the Sim-IPE activity was to engage AT and prelicensure nursing students in a realistic healthcare scenario to enhance knowledge about one another's profession, develop interprofessional skills, collaborate with one another, and communicate effectively as a team as they performed care.
Methods: This mixed methods study employed a one-time posttest design for a convenience sample of AT and prelicensure nursing students following a simulation intervention. Students completed the Student Perceptions of Interprofessional Clinical Education-Revised (SPICE-R) survey and answered open-ended response questions.
Results: Thirteen students (N = 13) from Cohort 1 and 12 students (N = 12) from Cohort 2 completed the SPICE-R survey. Most students strongly agreed/agreed for each of the SPICE-R survey questions. Qualitative findings indicated the students positively perceived the Sim-IPE activity as it helped them discover the value of interprofessional patient care.
Discussion: The quantitative findings indicated that the students found the Sim-IPE an effective learning methodology to achieve the objectives while the qualitative findings gave further insight into the students' perceptions of interprofessional teamwork and the value of the prebrief session conducted before the simulation. The findings will inform future Sim-IPE activities involving additional groups of healthcare students.
(© 2022 The Authors. Nursing Forum published by Wiley Periodicals LLC.)
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25. Antibody response to a third dose of SARS-CoV-2 vaccine in heart and lung transplant recipients. [2022]
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Alejo JL, Ruck JM, Chiang TPY, Abedon AT, Kim JD, Avery RK, Tobian AAR, Warren DS, Levan ML, Massie AB, Garonzik-Wang JM, Segev DL, and Werbel WA
Clinical transplantation [Clin Transplant] 2022 Nov; Vol. 36 (11), pp. e14818. Date of Electronic Publication: 2022 Sep 19.
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Humans, COVID-19 Vaccines, Antibody Formation, SARS-CoV-2, Transplant Recipients, Antibodies, Viral, COVID-19 epidemiology, COVID-19 prevention control, and Lung Transplantation
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Cooper, Alannah L., Mazzer, Jacqueline, Martin-Robins, Dipna, and Brown, Janie A.
- Journal of Clinical Nursing. November, 2022, Vol. 31 Issue 21-22, p3144, 11 p.
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Mackenzie, Isla S, Hawkey, Christopher J, Ford, Ian, Greenlaw, Nicola, Pigazzani, Filippo, Rogers, Amy, Struthers, Allan D, Begg, Alan G, Wei, Li, Avery, Anthony J, Taggar, Jaspal S, Walker, Andrew, Duce, Suzanne L, Barr, Rebecca J, Dumbleton, Jennifer S, Rooke, Evelien D, Townend, Jonathan N, Ritchie, Lewis D, MacDonald, Thomas M, Ahmed, Husnat, Arthur, Peter, Aziz, Jane, Barnes, Lawrence, Boyle, Sarah, Brighton, Tom, Brown, Morris, Caulfield, Mark, Dawson, Jesse, Denvir, Martin, Doney, Alexander SF, Doshi, Sagar, Dryburgh, Moira, Eddleston, Michael, Finlayson, Jim, Fuat, Ahmet, Furnace, Jacqueline, Grieve, JW Kerr, Guthrie, Greg, Ham, Sharon, Isaard, Emma, Jennings, Claudine, Johnson, Richard, Kerr, Claire, Khan, Sohail, Krishnan, Kailash, Long, Susan, Mackintosh, Anne, Macleod, Mary Joan, McCormack, Terry, McEleny, Paul, Morar, Monique, Nadir, Adnan, Newby, David, Petrie, Colin, Preiss, David, Ralston, Stuart, Randall, Marc, Routledge, Helen, Shakir, Saad, Sharma, Raj, Shepherd, Bridget, Sims, Don, Snedden, Gordon, Trevelyan, Jasper, Weir, Christopher, Weir, Robin, Wetherall, Kirsty, Wilson, Robbie, Wilson, Adam, and Zutis, Kris
- The Lancet; October 2022, Vol. 400 Issue: 10359 p1195-1205, 11p
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Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to determine whether allopurinol therapy improves major cardiovascular outcomes in patients with ischaemic heart disease.
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28. Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers. [2022]
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Hakkaart C, Pearson JF, Marquart L, Dennis J, Wiggins GAR, Barnes DR, Robinson BA, Mace PD, Aittomäki K, Andrulis IL, Arun BK, Azzollini J, Balmaña J, Barkardottir RB, Belhadj S, Berger L, Blok MJ, Boonen SE, Borde J, Bradbury AR, Brunet J, Buys SS, Caligo MA, Campbell I, Chung WK, Claes KBM, Collonge-Rame MA, Cook J, Cosgrove C, Couch FJ, Daly MB, Dandiker S, Davidson R, de la Hoya M, de Putter R, Delnatte C, Dhawan M, Diez O, Ding YC, Domchek SM, Donaldson A, Eason J, Easton DF, Ehrencrona H, Engel C, Evans DG, Faust U, Feliubadaló L, Fostira F, Friedman E, Frone M, Frost D, Garber J, Gayther SA, Gehrig A, Gesta P, Godwin AK, Goldgar DE, Greene MH, Hahnen E, Hake CR, Hamann U, Hansen TVO, Hauke J, Hentschel J, Herold N, Honisch E, Hulick PJ, Imyanitov EN, Isaacs C, Izatt L, Izquierdo A, Jakubowska A, James PA, Janavicius R, John EM, Joseph V, Karlan BY, Kemp Z, Kirk J, Konstantopoulou I, Koudijs M, Kwong A, Laitman Y, Lalloo F, Lasset C, Lautrup C, Lazaro C, Legrand C, Leslie G, Lesueur F, Mai PL, Manoukian S, Mari V, Martens JWM, McGuffog L, Mebirouk N, Meindl A, Miller A, Montagna M, Moserle L, Mouret-Fourme E, Musgrave H, Nambot S, Nathanson KL, Neuhausen SL, Nevanlinna H, Yie JNY, Nguyen-Dumont T, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Osorio A, Ott CE, Park SK, Parsons MT, Pedersen IS, Peixoto A, Perez-Segura P, Peterlongo P, Pocza T, Radice P, Ramser J, Rantala J, Rodriguez GC, Rønlund K, Rosenberg EH, Rossing M, Schmutzler RK, Shah PD, Sharif S, Sharma P, Side LE, Simard J, Singer CF, Snape K, Steinemann D, Stoppa-Lyonnet D, Sutter C, Tan YY, Teixeira MR, Teo SH, Thomassen M, Thull DL, Tischkowitz M, Toland AE, Trainer AH, Tripathi V, Tung N, van Engelen K, van Rensburg EJ, Vega A, Viel A, Walker L, Weitzel JN, Wevers MR, Chenevix-Trench G, Spurdle AB, Antoniou AC, and Walker LC
Communications biology [Commun Biol] 2022 Oct 06; Vol. 5 (1), pp. 1061. Date of Electronic Publication: 2022 Oct 06.
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BRCA1 Protein genetics, BRCA2 Protein genetics, DNA Copy Number Variations, Female, Genetic Predisposition to Disease, Heterozygote, Humans, RNA, Messenger, Breast Neoplasms genetics, and Breast Neoplasms pathology
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The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA2 variants remains relatively unknown. We conducted the largest genome-wide analysis of CNVs in 15,342 BRCA1 and 10,740 BRCA2 pathogenic variant carriers. We used these results to prioritise a candidate breast cancer risk-modifier gene for laboratory analysis and biological validation. Notably, the HR for deletions in BRCA1 suggested an elevated breast cancer risk estimate (hazard ratio (HR) = 1.21), 95% confidence interval (95% CI = 1.09-1.35) compared with non-CNV pathogenic variants. In contrast, deletions overlapping SULT1A1 suggested a decreased breast cancer risk (HR = 0.73, 95% CI 0.59-0.91) in BRCA1 pathogenic variant carriers. Functional analyses of SULT1A1 showed that reduced mRNA expression in pathogenic BRCA1 variant cells was associated with reduced cellular proliferation and reduced DNA damage after treatment with DNA damaging agents. These data provide evidence that deleterious variants in BRCA1 plus SULT1A1 deletions contribute to variable breast cancer risk in BRCA1 carriers.
(© 2022. The Author(s).)
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Vos JL, Raafs AG, van der Velde N, Germans T, Biesbroek PS, Roes K, Hirsch A, Heymans SRB, and Nijveldt R
Journal of the American Heart Association [J Am Heart Assoc] 2022 Oct 04; Vol. 11 (19), pp. e025106. Date of Electronic Publication: 2022 Sep 21.
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Arrhythmias, Cardiac, Contrast Media, Female, Gadolinium, Heart Atria, Humans, Magnetic Resonance Imaging, Cine methods, Magnetic Resonance Spectroscopy, Male, Predictive Value of Tests, Prognosis, Retrospective Studies, Stroke Volume, Ventricular Function, Left, Heart Failure, and Myocarditis diagnostic imaging
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Background Late gadolinium enhancement and left ventricular (LV) ejection fraction on cardiovascular magnetic resonance (CMR) are prognostic markers, but their predictive value for incident heart failure or life-threatening arrhythmias in acute myocarditis patients is limited. CMR-derived feature tracking provides a more sensitive analysis of myocardial function and may improve risk stratification in myocarditis. In this study, the prognostic value of LV, right ventricular, and left atrial strain in acute myocarditis patients is evaluated. Methods and Results In this multicenter retrospective study, patients with CMR-proven acute myocarditis were included. The primary end point was occurrence of major adverse cardiovascular events: all-cause mortality, heart transplantation, heart failure hospitalizations, and life threatening arrhythmias. LV global longitudinal strain, global circumferential strain and global radial strain, right ventricular-global longitudinal strain and left atrial strain were measured. Unadjusted and adjusted cox proportional hazard regression analysis were performed. In total, 162 CMR-proven myocarditis patients were included (41 ± 17 years, 75% men). Mean LV ejection fraction was 51 ± 12%, and 144 (89%) patients had presence of late gadolinium enhancement. Major adverse cardiovascular events occurred in 29 (18%) patients during a follow-up of 5.5 (2.2-8.3) years. All LV strain parameters were independent predictors of outcome beyond clinical features, LV ejection fraction and late gadolinium enhancement (LV-global longitudinal strain: hazard ratio [HR] 1.07, P =0.02; LV-global circumferential strain: HR 1.15, P =0.02; LV-global radial strain: HR 0.98, P =0.03), but right ventricular or left atrial strain did not predict outcome. Conclusions CMR-derived LV strain analysis provides independent prognostic value on top of clinical parameters, LV ejection fraction and late gadolinium enhancement in acute myocarditis patients, while left atrial and right ventricular strain seem to be of less importance.
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Alejo JL, Mitchell J, Chiang TP, Chang A, Abedon AT, Werbel WA, Boyarsky BJ, Zeiser LB, Avery RK, Tobian AAR, Levan ML, Warren DS, Massie AB, Moore LW, Guha A, Huang HJ, Knight RJ, Gaber AO, Ghobrial RM, Garonzik-Wang JM, Segev DL, and Bae S
Transplantation [Transplantation] 2022 Oct 01; Vol. 106 (10), pp. e452-e460. Date of Electronic Publication: 2022 Jul 21.
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Antibodies, Viral, Antibody Formation, BNT162 Vaccine, Humans, Immunosuppressive Agents adverse effects, Machine Learning, Mycophenolic Acid, SARS-CoV-2, Vaccines, Vaccines, Synthetic, mRNA Vaccines, COVID-19 prevention control, COVID-19 Vaccines adverse effects, and Transplant Recipients
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Background: Solid organ transplant recipients (SOTRs) are less likely to mount an antibody response to SARS-CoV-2 mRNA vaccines. Understanding risk factors for impaired vaccine response can guide strategies for antibody testing and additional vaccine dose recommendations.
Methods: Using a nationwide observational cohort of 1031 SOTRs, we created a machine learning model to explore, identify, rank, and quantify the association of 19 clinical factors with antibody responses to 2 doses of SARS-CoV-2 mRNA vaccines. External validation of the model was performed using a cohort of 512 SOTRs at Houston Methodist Hospital.
Results: Mycophenolate mofetil use, a shorter time since transplant, and older age were the strongest predictors of a negative antibody response, collectively contributing to 76% of the model's prediction performance. Other clinical factors, including transplanted organ, vaccine type (mRNA-1273 versus BNT162b2), sex, race, and other immunosuppressants, showed comparatively weaker associations with an antibody response. This model showed moderate prediction performance, with an area under the receiver operating characteristic curve of 0.79 in our cohort and 0.67 in the external validation cohort. An online calculator based on our prediction model is available at http://transplantmodels.com/covidvaccine/ .
Conclusions: Our machine learning model helps understand which transplant patients need closer follow-up and additional doses of vaccine to achieve protective immunity. The online calculator based on this model can be incorporated into transplant providers' practice to facilitate patient-centric, precision risk stratification and inform vaccination strategies among SOTRs.
Competing Interests: D.L.S. has the following financial disclosures: consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, Thermo Fisher Scientific, Regeneron, and AstraZeneca. R.K.A. has grant/research support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, and Takeda/Shire. M.L.L. is the Social Media Editor for Transplantation and is a consultant for Takeda/Shire and Patients Like Me. The other authors declare no conflicts of interest.
(Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
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Chang A, Strauss AT, Alejo JL, Chiang TP, Hernandez NF, Zeiser LB, Boyarsky BJ, Avery RK, Tobian AAR, Levan ML, Warren DS, Garonzik-Wang JM, Massie AB, Werbel WA, and Segev DL
Hepatology communications [Hepatol Commun] 2022 Oct; Vol. 6 (10), pp. 2990-2992. Date of Electronic Publication: 2022 Jul 05.
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Antibodies, Humans, Kinetics, RNA, Messenger, SARS-CoV-2 genetics, Vaccination, COVID-19 prevention control, and Liver Transplantation
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Link-Gelles, Ruth, Lutterloh, Emily, Ruppert, Patricia Schnabel, Backenson, P. Bryon, St. George, Kirsten, Rosenberg, Eli S., Anderson, Bridget J., Fuschino, Meghan, Popowich, Michael, Punjabi, Chitra, Souto, Maria, McKay, Kevin, Rulli, Samuel, Insaf, Tabassum, Hill, Dustin, Kumar, Jessica, Gelman, Irina, Jorba, Jaume, Ng, Terry Fei Fan, Gerloff, Nancy, Masters, Nina B., Lopez, Adriana, Dooling, Kathleen, Stokley, Shannon, Kidd, Sarah, Oberste, M. Steven, Routh, Janell, Routh, Janell, Belgasmi, Hanen, Brister, Barrett, Bullows, James E., Burns, Cara C., Castro, Christina J., Cory, Janine, Dybdahl-Sissoko, Naomi, Emery, Brian D., English, Randall, Frolov, Ann D., Getachew, Halle, Henderson, Elizabeth, Hess, Alexandra, Mason, Karen, Mercante, Jeffrey W., Miles, Stacey Jeffries, Liu, Hongmei, Marine, Rachel L., Momin, Nehalraza, Pang, Hong, Perry, Daniel, Rogers, Shannon L., Short, Brandon, Sun, Hong, Tobolowsky, Farrell, Yee, Eileen, Hughes, Scott, Hygiene, Mental, Omoregie, Enoma, Hygiene, Mental, Rosen, Jennifer B., Hygiene, Mental, Zucker, Jane R., Hygiene, Mental, Alazawi, Mohammed, Bauer, Ursula, Godinez, Alex, Hanson, Brianna, Heslin, Eugene, McDonald, James, Mita-Mendoza, Neida K., Meldrum, Megan, Neigel, Dana, Suitor, Robin, Larsen, David A., Egan, Christina, Faraci, Nicola, Feumba, G. Stephanie, Gray, Todd, Lamson, Daryl, Laplante, Jennifer, McDonough, Kathleen, Migliore, Natalie, Moghe, Amruta, Ogbamikael, Simon, Plitnick, Jonathan, Ramani, Rama, Rickerman, Lindsey, Rist, Erik, Schoultz, Lynsey, Shudt, Matthew, Krauchuk, Julie, Medina, Eric, Lawler, Jacqueline, Boss, Heather, Barca, Emanuele, Ghazali, Dabish B., Goyal, Tarini, Marinelli, Sean J.P., Roberts, Jackson A., Russo, Grace B., Thakur, Kiran T., and Yang, Vivian Q.
- American Journal of Transplantation. October, 2022, Vol. 22 Issue 10, p2470, 5 p.
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Weedon MN, Jones SE, Lane JM, Lee J, Ollila HM, Dawes A, Tyrrell J, Beaumont RN, Partonen T, Merikanto I, Rich SS, Rotter JI, Frayling TM, Rutter MK, Redline S, Sofer T, Saxena R, and Wood AR
PLoS genetics [PLoS Genet] 2022 Sep 22; Vol. 18 (9), pp. e1010356. Date of Electronic Publication: 2022 Sep 22 (Print Publication: 2022).
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Humans, Phenotype, Receptors, G-Protein-Coupled genetics, Sleep genetics, Circadian Rhythm genetics, and Sleep Wake Disorders genetics
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Rare variants in ten genes have been reported to cause Mendelian sleep conditions characterised by extreme sleep duration or timing. These include familial natural short sleep (ADRB1, DEC2/BHLHE41, GRM1 and NPSR1), advanced sleep phase (PER2, PER3, CRY2, CSNK1D and TIMELESS) and delayed sleep phase (CRY1). The association of variants in these genes with extreme sleep conditions were usually based on clinically ascertained families, and their effects when identified in the population are unknown. We aimed to determine the effects of these variants on sleep traits in large population-based cohorts. We performed genetic association analysis of variants previously reported to be causal for Mendelian sleep and circadian conditions. Analyses were performed using 191,929 individuals with data on sleep and whole-exome or genome-sequence data from 4 population-based studies: UK Biobank, FINRISK, Health-2000-2001, and the Multi-Ethnic Study of Atherosclerosis (MESA). We identified sleep disorders from self-report, hospital and primary care data. We estimated sleep duration and timing measures from self-report and accelerometery data. We identified carriers for 10 out of 12 previously reported pathogenic variants for 8 of the 10 genes. They ranged in frequency from 1 individual with the variant in CSNK1D to 1,574 individuals with a reported variant in the PER3 gene in the UK Biobank. No carriers for variants reported in NPSR1 or PER2 were identified. We found no association between variants analyzed and extreme sleep or circadian phenotypes. Using sleep timing as a proxy measure for sleep phase, only PER3 and CRY1 variants demonstrated association with earlier and later sleep timing, respectively; however, the magnitude of effect was smaller than previously reported (sleep midpoint ~7 mins earlier and ~5 mins later, respectively). We also performed burden tests of protein truncating (PTVs) or rare missense variants for the 10 genes. Only PTVs in PER2 and PER3 were associated with a relevant trait (for example, 64 individuals with a PTV in PER2 had an odds ratio of 4.4 for being "definitely a morning person", P = 4x10-8; and had a 57-minute earlier midpoint sleep, P = 5x10-7). Our results indicate that previously reported variants for Mendelian sleep and circadian conditions are often not highly penetrant when ascertained incidentally from the general population.
Competing Interests: The authors have declared that no competing interests exist.
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Bowden J, Harrison NJ, Caruso J, Room R, Pettigrew S, Olver I, and Miller C
BMC public health [BMC Public Health] 2022 Sep 19; Vol. 22 (1), pp. 1775. Date of Electronic Publication: 2022 Sep 19.
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Adult, Australia epidemiology, Female, Humans, Male, Risk Factors, Surveys and Questionnaires, Alcohol Drinking epidemiology, and Diet
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Background: Alcohol is a discretionary, energy dense, dietary component. Compared to non-drinkers, people who consume alcohol report higher total energy intake and may be at increased risk of weight gain, overweight, and obesity, which are key preventable risk factors for illness. However, accurate consumer knowledge of the energy content in alcohol is low. To inform future behaviour change interventions among drinkers, this study investigated individual characteristics associated with changing alcohol consumption due to energy-related concerns.
Methods: An online survey was undertaken with 801 Australian adult drinkers (18-59 years, 50.2% female), i.e. who consumed alcohol at least monthly. In addition to demographic and health-related characteristics, participants reported past-year alcohol consumption, past-year reductions in alcohol consumption, frequency of harm minimisation strategy use (when consuming alcohol), and frequency of changing alcohol consumption behaviours because of energy-related concerns.
Results: When prompted, 62.5% of participants reported changing alcohol consumption for energy-related reasons at least 'sometimes'. Women, those aged 30-44 years, metropolitan residents, those with household income $80,001-120,000, and risky/more frequent drinkers had increased odds of changing consumption because of energy-related concerns, and unemployed respondents had reduced odds.
Conclusions: Results indicate that some sociodemographic groups are changing alcohol consumption for energy-related reasons, but others are not, representing an underutilised opportunity for health promotion communication. Further research should investigate whether messaging to increase awareness of alcohol energy content, including through systems-based policy actions such as nutritional/energy product labelling, would motivate reduced consumption across a broader range of drinkers.
(© 2022. The Author(s).)
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Alejo JL, Chiang TPY, Bowles Zeiser L, Kim JD, Mitchell J, Avery RK, Tobian AAR, Abedon RR, Levan ML, Warren DS, Garonzik-Wang JM, Massie AB, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 Sep 01; Vol. 106 (9), pp. e413-e415. Date of Electronic Publication: 2022 Jun 03.
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Humans, Incidence, Transplant Recipients, COVID-19 epidemiology, COVID-19 prevention control, and Organ Transplantation adverse effects
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Competing Interests: D.L.S. has the following financial disclosures: consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, Thermo Fisher Scientific, Regeneron, and AstraZeneca. R.K.A. is an associate editor of Transplantation and has grant/research support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, Regeneron, and Takeda/Shire. M.L.L. is a Social Media Editor for Transplantation and receives consulting honoraria that are not related to her authorship of the article from Takeda/Patients Like Me. The other authors declare no conflicts of interest.
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Chang A, Mitchell J, Alejo JL, Chiang TPY, Abedon AT, Kim JD, Avery RK, Tobian AAR, Levan ML, Warren DS, Garonzik-Wang JM, Massie AB, Segev DL, and Werbel WA
Clinical transplantation [Clin Transplant] 2022 Sep; Vol. 36 (9), pp. e14772. Date of Electronic Publication: 2022 Jul 19.
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Ad26COVS1, Antibodies, Viral, COVID-19 Vaccines, Humans, RNA, Messenger, SARS-CoV-2 genetics, Transplant Recipients, COVID-19 epidemiology, COVID-19 prevention control, and Organ Transplantation adverse effects
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Chiang TP, Alejo JL, Mitchell J, Kim JD, Abedon AT, Karaba AH, Thomas L, Levan ML, Garonzik-Wang JM, Avery RK, Pekosz A, Clarke WA, Warren DS, Tobian AAR, Massie AB, Segev DL, and Werbel WA
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2022 Sep; Vol. 22 (9), pp. 2254-2260. Date of Electronic Publication: 2022 May 03.
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Antibodies, Viral, COVID-19 Vaccines adverse effects, Humans, RNA, Messenger genetics, SARS-CoV-2, Transplant Recipients, Vaccination, 2019-nCoV Vaccine mRNA-1273 adverse effects, BNT162 Vaccine adverse effects, COVID-19 epidemiology, COVID-19 prevention control, Influenza Vaccines, and Organ Transplantation adverse effects
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Heterologous vaccination ("mixing platforms") for the third (D3) dose of SARS-CoV-2 vaccine is a potential strategy to improve antibody responses in solid organ transplant recipients (SOTRs), but data are mixed regarding potential differential immunogenicity. We assessed for differences in immunogenicity and tolerability of homologous (BNT162b2 or mRNA-1273; D3-mRNA) versus heterologous (Ad.26.COV2.S; D3-JJ) D3 among 377 SARS-CoV-2-infection naïve SOTRs who remained seronegative after two mRNA vaccines. We measured anti-spike titers and used weighted Poisson regression to evaluate seroconversion and development of high-titers, comparing D3-JJ to D3-mRNA, at 1-, 3-, and 6 month post-D3. 1-month post-D3, seroconversion (63% vs. 52%, p = .3) and development of high-titers (29% vs. 25%, p = .7) were comparable between D3-JJ and D3-mRNA recipients. 3 month post-D3, D3-JJ recipients were 1.4-fold more likely to seroconvert (80% vs. 57%, weighted incidence-rate-ratio: wIRR = 1.10 1.40 1.77 , p = .006) but not more likely to develop high-titers (27% vs. 22%, wIRR = 0.44 0.92 1.93 , p = .8). 6 month post-D3, D3-JJ recipients were 1.41-fold more likely to seroconvert (88% vs. 59%, wIRR = 1.04 1.41 1.93 , p = .029) and 2.63-fold more likely to develop high-titers (59% vs. 21%, wIRR = 1.38 2.63 5.00 , p = .003). There was no differential signal in alloimmune events or reactogenicity between platforms. SOTRs without antibody response after two mRNA vaccines may derive benefit from heterologous Ad.26.COV2.S D3.
(© 2022 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons.)
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Mullins, E., Perry, A., Banerjee, J., Townson, J., Grozeva, D., Milton, R., Kirby, N., Playle, R., Bourne, T., Lees, C., Rand, Abby, Khunda, Aethele, Roztocil, Ales, Kermack, Alexandra J, Mackay, Ami, Verma, Amit, Ahmed, Amna, Mahdi, Amy, Fayadh, Anam, Dall'Asta, Andrea, Harrington, Andrea, Gerede, Angeliki, Nejad, Avideah, Sinha, Barkha, Peers, Beth, Hammond, Bev, Ajay, Bini, Dixon, Caroline, Everden, Caroline, Heal, Carrie, Bressington, Catherine, Wyatt, Cheryl, Flood, Chris, Möller-Christensen, Christine, O'Brien, Clare, Glenn-Sansum, Coralie, Huson, Coralie, Rallis, Dimitrios, Perkins, Donna, Southam, Donna, Wixted, Donna, Viner, Alexandra, Asghar, Anila, Nicoll, Antony, Knight, Caroline, McKeown, Gillian, Divakar, Hema, Panagiotis Christofidis, Plastiras, Satodia, Prakash, Liebling, Rachel, Arya, Rita, Kousar, Rukhsana, Gada, Ruta, Narayanan, Sankara, Iliodromiti, Stamatina, Giri, Vibha, Vasu, Vimal, Hassan, Wassim, Woodward, Zoe, Mutema, E., MK Jarvie, Eleanor, Romero, Elena, Collins, Emma, Meadows, Emma, Mills, Emma, Tanton, Emma, Vrapi, Enxhi, Darmawan, Ernawati, Barra, Fabio, Prefumo, Federico, Lee, Fidelma, Martin, Hayley L., Gbinigie, Helen, Millward, Helen, Owen, Hilary, Crawford, Isobel, Tipper, Jacqueline, Jennings, Jacqui, Raven, Jamie-Louise, Cantliffe, Jane, Radford, Jane, Cresswell, Janet, Syson, Jennifer, Brain, Jessie, Mead, Joanna, Mossop, Jude, Goddard, Julie, Grindey, Julie, Cloherty, Karen, Watkins, Karen, Robinson, Kate, Barker, Katie, Elliott, Kerry, Hinshaw, Kim, Revell, Kirsty, Camarasa, Laura, Harris, Laura, Windsor, Laurie, Sherris, Leanne, Chapman, Lianne, Bishop, Linda, Chiu Yee POON, Liona, Frankland, Lisa, Glyn-Jones, Liz, Emmet, Louise, Swaminathan, Louise, Aldika Akbar, M.I, Armstrong, Maggie, Gorti, Mahalakshmi, Black, Mairead, Malarselvi, Mani, Khare, Manjiri, Chester, Mark, Andrasova, Martina, Bray, Maryanne, Parra-Cordero, Mauro, Roland Berger, MD, Anderson, Michelle, Anim-Somuah, Millicent, XIE, Mingxing, Bourke, Miriam, Elbahnasawy, Mohamed, Sobhy Bakry, Mohamed, Shah, Ahmar, RATHER, BA, Churchill, David, Wee, Ling, Kidwai, Salman, Balling, Trevor, Amin, Allison, Essien, Sandra, Sameena Kausar, Ms, Rajeswary, Ms.Jyothi, Javaid, Muglu, Aladangady, Narendra, Shah, Neil, Bale, Nichola, Mason, Nicky, Wu, Pensée, Margarit, Lavinia, Zill-e-Huma, Rabia, Newport, Rachel, Hughes, Robin, Jokhi, Roobin, Mansfield, Roshni, Davies, Ru, Davies, Ruth, Ratcliffe, Sam, Greer, Sandra, Coxon, Sarah, Ekladios, Sarah, Stables, Sarah, McCooty, Shanteela, Gowans, Sharon, Jones, Sharon, Jaleel, Shazia, Higgins, Shelly, Halawa, Sherry, Harrington, Siân C, Robinson, Sophie, Nallapeta, Soum, Grigsby, Stephanie, Blunden, Susara, Tiziana Frusca, SSA, Sukrutha, Veerareddy, Atkinson, Vicki, Murtha, Victoria, Germán Caro, Waldo, and Garner, Zoe
- European Journal of Obstetrics & Gynecology and Reproductive Biology. September, 2022, Vol. 276, p161.
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Turkova, Anna, Waalewijn, Hylke, Chan, Man K, Bollen, Pauline D J, Bwakura-Dangarembizi, Mutsa F, Kekitiinwa, Adeodata R, Cotton, Mark F, Lugemwa, Abbas, Variava, Ebrahim, Ahimbisibwe, Grace Miriam, Srirompotong, Ussanee, Mumbiro, Vivian, Amuge, Pauline, Zuidewind, Peter, Ali, Shabinah, Kityo, Cissy M, Archary, Moherndran, Ferrand, Rashida A, Violari, Avy, Gibb, Diana M, Burger, David M, Ford, Deborah, Colbers, Angela, Mehar (nee Abdulla), Amina Farhana, Abraham, Pattamukkil, Abrams, Elaine, Acero, Judith, Agaba, Gerald Muzorah, Ahimbisibwe, Grace, Ainebyoona, Barbara, Akobye, Winnie, Akhalwaya, Yasmeen, Akoojee, Nazim, Ali, Shabinah S., Amuge, Pauline, Andrea, Catherine, Muñoz Fernandez, Maria Angeles, Ankunda, Rogers, Rutebarika, Diana Antonia, Anugulruengkitt, Suvaporn, Apollo, Tsitsi, Archary, Moherndran, Arendze, Ronelle, Ategeka, Juliet, Atim, Eunice, Atwine, Lorna, Babiker, Abdel, Babirye, Sarah, Babu, Enock, Bagirigomwa, Edward, Baita, Angella, Balamusani, David, Baliram, Patsy, Baliruno, David, Ball, Colin, Balwa, Henry, Bamford, Alasdair, Bandi, Srini, Barker, Dominique, Barlow-Mosha, Linda, Bbuye, Dickson, Begum, Shazia, Behuhuma, Osee, Bernays, Sarah, Besigye, Rogers, Bester, Maria, Bhiri, Joyline, Bilardi, Davide, Bird, Kristien, Bollen, Pauline, Borg, Chiara, Borges Da Silva, Anne-Marie, Brown, Jackie, Bruno, Elena, Bunupuradah, Torsak, Burger, David, Buthelezi, Nomzamo, Bwakura-Dangarembizi, Mutsa, Byaruhanga, Africanus, Calvert, Joanna, Casey, Petronelle, Cassim, Haseena, Cebekhulu, Sphiwee, Chailert, Sanuphong, Chalermpantmetagul, Suwalai, Chamjamrat, Wanna, Chan, Man, Chandiwana, Precious, Chankun, Thannapat, Chanthaburanun, Sararut, Chanto, Nuttawut, Chidziva, Ennie, Chikowore, Minenhle, Chimanzi, Joy, Chinwong, Dujrudee, Chitongo, Stuart, Chitsamatanga, Moses, Choga, Joshua, Chutima, Duangrat, Clayden, Polly, Coelho, Alexandra, Colbers, Angela, Compagnucci, Alexandra, Constança Mendes, Ana, Conway, Magda, Cotton, Mark F., Crawley, Jane, Cressey, Tim R., Crisp, Jacky, Matos, Ana Cristina, Dadan, Sumaya, Daglish, Jacqui, Danaviah, Siva, Daniel, Tseleng, De Rossi, Anita, Denjanta, Sukanda, Dobbels, Els, Dowie, Maria, Dube, Prosper, Dube, Benedictor, Dudakia, Nimisha, Elwana, Alice, Epalza, Cristina, Eram, David, Erasmus, Juan, Erim, Peter, Escosa Garcia, Luis, Essack, Zaakirah, Estepa, Carolina, Etima, Monica, Fernandes, Alexandre, Fernandez, Maite, Fitzgerald, Felicity, Flynn, Jacquie, Ford, Deborah, Fortuny Guasch, Claudia, Foster, Caroline, Fourie, George, Fourie, Yolandie, Foxall, Sophie, Frank, Derusha, Gandhi, Kate, Garcia, India, Gartner, Kathleen, Gasa, Joshua, Gasa, Gugu, Giaquinto, Carlo, Gibb, Diana M., Gomez Rico, Coral, Gomez-Pena, Daniel, Gondo, Secrecy, Goodman, Anna, Gorreti Nakalema, Maria, Gozhora, Winnie, Greetanukroh, Pisut, Gregorio Maranon, Biobanco, Grossele, Tiziana, Gwande, Shamiso, Gwaze, Tapiwa, Gwenzi, Tsitsi, Hakim, James, Hakiza, Emmanuel, Kaka, Abdul Hamid, Harley, Ashley, Isaacs, Mornay, Isabirye, Richard, Ishemunyoro, Wilber, Jacobs, Tom, Jafta, Lungile, Jamil, Nasir, Janse van Rensburg, Anita Janse, Jeaven, Vinesh, Mellado Peña, Maria José, Jourdain, Gonzague, Juliet, Katabalwa, Jumpimai, Thidarat, Junkaew, Raungwit, Jupimai, Thidarat, Kaahwa, Winfred, Kabasonga, Mildred, Kaboggoza, Olivia, Kadhuba, Rose Jacqueline, Kaewbundit, Ampika, Kaewmamueng, Kanyanee, Kafufu, Bosco, Kakayi, Brenda, Kamboua, Phakamas, Kanjanavanit, Suparat, Kasangaki, Gladys, Kasipong, Naruporn, Kasozi, Miriam, Kataike, Hajira, Katemba, Chrispus, Kaudha, Elizabeth, Kekane, Nkata, Kekitiinwa, Adeodata R., Keminyeto, Edridah, Khamduang, Woottichai, Khamjakkaew, Warunee, Khamkon, Jiraporn, Khannak, Sasipass, Khatngam, Orapin, Khayanchoomnoom, Tassawan, Khumalo, Busi, Khunene, Mirriam, Khusuwan, Suwimon, Kibalama, Phionah, Kibenge, Robinah, Kirabira, Anthony, Kityo, Cissy M., Kiyimba, Lameck, Klein, Nigel, Klinprung, Soraya, Kobbe, Robin, Kobusingye, Olivia, Kobusungye, Josephine, Kongponoi, Areerat, Königs, Christoph, Koole, Olivier, Kouakam, Christelle, Krueduangkam, Nitinart, Kruenual, Namthip, Kunjaroenrut, Nuananong, Kyambadde, Raymonds, Kyobutungi, Priscilla, Kyomuhendo, Flavia, Kyomukama, Erinah, Lakha, Reshma, Langa, Cleopatra, Laomanit, Laddawan, Lebotsa, Emily, Leenasirimakul, Prattana, Lekku, Lawrence, Lensen, Sarah, Leroy, Valériane, Li, Jin, Liberty, Afaaf, Limplertjareanwanich, Juthamas, Little, Emma, Lugemwa, Abbas, Lutalo, Ezra, Jimenez, Jose Luis, Lyall, Hermione, MacDonald, Candice, Machache, Gladness, Madlala, Penelope, Madonsela, Tryphina, Maduna, Nomfundo, Maena, Joel, Mahanontharit, Apicha, Makanga, Collin, Makola, Candice, Makumbi, Shafic, Malgraaf, Lucille, Mamiane, Angelous, Mantkowski, Felicia, Mapfumo, Wendy, Marques, Laura, Mugagga, Agnes Mary, Maseko, Lindiwe, Masienyane, Tshepiso, Mathiba, Ruth, Matimba, Farai, Mawlana, Sajeeda, Mayanja, Emmanuel, Mayat, Fatima, Mbabazi, Ritah, Mbadaliga, Nokuthula, Mbasani, Faith, McClaughlin, Kathleen, McIlleron, Helen, Meethaisong, Watchara, Mendez Garcia, Patricia, Miwanda, Annet, Miranda, Carlota, Mkhize, Siphiwe, Mmolawa, Kgosimang, Mngqibisa, Rosie, Mohamed, Fatima, Moloantoa, Tumelo, Monametsi, Maletsatsi, Montero, Samuel, Moore, Cecilia L., Mosia, Rejoice, Moyo, Columbus, Mthethwa, Mumsy, Mudzingwa, Shepherd, Mudzviti, Tawona, Mujuru, Hilda, Mujyambere, Emmanuel, Mukanganiki, Trust, Mukisa Williams, Cynthia, Mulder, Mark, Mulima, Disan, Mulindwa, Alice, Mumbiro, Vivian, Mupambireyi, Zivai, Murciano Cabeza, Alba, Murungi, Herbert, Murungu, Dorothy, Musarurwa, Sandra, Musiime, Victor, Musiime, Alex V., Musisi, Maria, Musoke, Philippa, Musoke Nakirya, Barbara, Musoro, Godfrey, Musumba, Sharif, Mustafa, Sobia, Mutsai, Shirley, Mwesigwa Rubondo, Phyllis, Naabalamba, Mariam, Nagawa, Immaculate, Naidoo, Allemah, Nakabuye, Shamim, Nakabuye, Sarah, Nakalanzi, Sarah, Nalubwama, Justine, Nalugo, Annet, Nalusiba, Stella, Namajja, Clementine, Namanda, Sylvia, Namayanja, Paula, Nambi, Esther, Namuddu, Rachael Kikabi, Namukwaya, Stella, Namuli, Florence, Namusanje, Josephine, Namwanje, Rosemary, Nanan-kanjee, Anusha, Nanduudu, Annet, Nankunda, Charity, Baddokwaya, Joanita Nankya, Nannungi, Maria, Nansamba, Winnie, Nanthapisal, Kesdao, Nanyonjo, Juliet, Na-Rajsima, Sathaporn, Nasaazi, Claire, Nascimento, Helena, Nastouli, Eleni, Songtaweesin, Wipaporn Natalie, Nathoo, Kusum, Natuhurira, Ian, Nazzinda, Rashidah, Ncgaba, Thabisa, Ndigendawani, Milly, Ndlovu, Makhosonke, Nentsa, Georgina, Ngampiyaskul, Chaiwat, Ngcobo, Ntombenhle, Ngo Giang Huong, Nicole, Ngwaru, Pia, Nhema, Ruth, Ninsiima, Emily, Ninsiima, Gloria, Nkalo Phiri, Misheck, Noguera Julian, Antoni, Nolan, Monica, Noppakaorattanamanee, Thornthun, Nsibuka Kisekka, Muzamil, Nsirim, Eniola, Nundlal, Rashina, Nunes, Rosita, Nyantsa, Lungile, Nyati, Mandisa, O'Riordan, Sean, Ocitti Labeja, Paul, Odoch, Denis, Oguntimehin, Rachel, Ojok, Martin, Onen, Geoffrey, Orange, Wilma, Ounchanum, Pradthana, Ouma, Benson, Padrao, Andreia, Pako, Deborah, Parker, Anna, Pasko-Szcech, Malgorzata, Patel, Reena, Peongjakta, Rukchanok, Petpranee, Turian, Phillips, Tasmin, Philps, Jackie, Picault, Laura, Pieterse, Sonja, Pinheiro, Helena, Pongprapass, Supawadee, Pozniak, Anton, Prendergast, Andrew, Prieto Tato, Luis, Puangmalai, Patcharee, Puthanakit, Thanyawee, Rakgokong, Modiehi, Ramos, Helena, Ramsagar, Nastassja, Rau, Cornelius, Riault, Yoann, Rojo Conejo, Pablo, Clark, Basiimwa Roy, Rubanga, Eddie, Rubinga, Baker, Ruklao, Chutima, Runarassamee, Pattira, Rutebarika, Diana Antonia, Saenjum, Chalermpong, Saewtrakool, Chayakorn, Saidi, Yacine, Sainz Costa, Talia, Saisaengjan, Chutima, Sakwa, Rebecca, Sarfati, Tatiana, Sbisi, Noshalaza, Scheppers, Dihedile, Schultze-Strasser, Stephan, Schulze-Sturm, Ulf, Scott, Karen, Seeley, Janet, Serunjogi, Robert, Sewnarain, Leora, Shakeshaft, Clare, Sidhoo, Subashinie, Shibemba, Mercy, Shingadia, Delane, Singh, Sheleika, Sirirungsi, Wasna, Sithebe, Sibongile, Smit, Theresa, Smith, Kurt, Smuts, Marlize, Spyer, Moira, Sripaoraya, Worathip, Srirompotong, Ussanee, Srisuk, Warunee, Ssenyonga, Mark, Sudsaard, Patamawadee, Sukrakanchana, Praornsuda, Tearsansern, Pathanee, Teixeira, Carla, Than-in-at, Kanchana, Thapwai, Thitiwat, Thaweesombat, Yupawan, Thewsoongnoen, Jutarat, Thiébaut, Rodolphe, Thomason, Margaret, Thrasyvoulou, Laura, Thungkham, Khanungnit, Tikabibamu, Judith, Tinago, Gloria, Trairat, Ketmookda, Tudor-Williams, Gareth, Tukamushaba, Mercy, Tukwasibwe, Deogratiuos, Tumusiime, Julius, Tuna, Joana, Turkova, Anna, Turner, Rebecca, Udomvised, Arttasid, Vadee, Aasia, Van Huyssteen, Hesti, Van Looy, Nadine, Variava, Ebrahim, Vaughan-Gordon, Yvonne, Vecchia, Giulio, Violari, Avy, Vowden, Richard, Waalewijn, Hylke, Wampamba, Rebecca, Welch, Steve, Weller, Ian, Weza, Sibusisiwe, White, Ellen, White, Ian, Widuch, Kaja, Wilkes, Helen, Wimonklang, Sookpanee, Wynne, Ben, Yingyong, Pacharaporn, Nakawungu, Zaam Zinda, and Zuidewind, Peter
- The Lancet HIV; September 2022, Vol. 9 Issue: 9 pe627-e637, 11p
- Abstract
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Children with HIV-associated tuberculosis (TB) have few antiretroviral therapy (ART) options. We aimed to evaluate the safety and pharmacokinetics of dolutegravir twice-daily dosing in children receiving rifampicin for HIV-associated TB.
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Amuge, Pauline, Lugemwa, Abbas, Wynne, Ben, Mujuru, Hilda A, Violari, Avy, Kityo, Cissy M, Archary, Moherndran, Variava, Ebrahim, White, Ellen, Turner, Rebecca M, Shakeshaft, Clare, Ali, Shabinah, Nathoo, Kusum J, Atwine, Lorna, Liberty, Afaaf, Bbuye, Dickson, Kaudha, Elizabeth, Mngqibisa, Rosie, Mosala, Modehei, Mumbiro, Vivian, Nanduudu, Annet, Ankunda, Rogers, Maseko, Lindiwe, Kekitiinwa, Adeodata R, Giaquinto, Carlo, Rojo, Pablo, Gibb, Diana M, Turkova, Anna, Ford, Deborah, Mehar (nee Abdulla), Amina Farhana, Abraham, Pattamukkil, Abrams, Elaine, Acero, Judith, Agaba, Gerald Muzorah, Ahimbisibwe, Grace, Ainebyoona, Barbara, Akobye, Winnie, Akhalwaya, Yasmeen, Akoojee, Nazim, Ali, Shabinah S., Amuge, Pauline, Andrea, Catherine, Muñoz Fernandez, Maria Angeles, Ankunda, Rogers, Rutebarika, Diana Antonia, Anugulruengkitt, Suvaporn, Apollo, Tsitsi, Archary, Moherndran, Arendze, Ronelle, Ategeka, Juliet, Atim, Eunice, Atwine, Lorna, Babiker, Abdel, Babirye, Sarah, Babu, Enock, Bagirigomwa, Edward, Baita, Angella, Balamusani, David, Baliram, Patsy, Baliruno, David, Ball, Colin, Balwa, Henry, Bamford, Alasdair, Bandi, Srini, Barker, Dominique, Barlow-Mosha, Linda, Bbuye, Dickson, Begum, Shazia, Behuhuma, Osee, Bernays, Sarah, Besigye, Rogers, Bester, Maria, Bhiri, Joyline, Bilardi, Davide, Bird, Kristien, Bollen, Pauline, Borg, Chiara, Borges Da Silva, Anne-Marie, Brown, Jackie, Bruno, Elena, Bunupuradah, Torsak, Burger, David, Buthelezi, Nomzamo, Bwakura-Dangarembizi, Mutsa, Byaruhanga, Africanus, Calvert, Joanna, Casey, Petronelle, Cassim, Haseena, Cebekhulu, Sphiwee, Chailert, Sanuphong, Chalermpantmetagul, Suwalai, Chamjamrat, Wanna, Chan, Man, Chandiwana, Precious, Chankun, Thannapat, Chanthaburanun, Sararut, Chanto, Nuttawut, Chidziva, Ennie, Chikowore, Minenhle, Chimanzi, Joy, Chinwong, Dujrudee, Chitongo, Stuart, Chitsamatanga, Moses, Choga, Joshua, Chutima, Duangrat, Clayden, Polly, Coelho, Alexandra, Colbers, Angela, Compagnucci, Alexandra, Constança Mendes, Ana, Conway, Magda, Cotton, Mark F., Crawley, Jane, Cressey, Tim R., Crisp, Jacky, Matos, Ana Cristina, Dadan, Sumaya, Daglish, Jacqui, Danaviah, Siva, Daniel, Tseleng, De Rossi, Anita, Denjanta, Sukanda, Dobbels, Els, Dowie, Maria, Dube, Prosper, Dube, Benedictor, Dudakia, Nimisha, Elwana, Alice, Epalza, Cristina, Eram, David, Erasmus, Juan, Erim, Peter, Escosa Garcia, Luis, Essack, Zaakirah, Estepa, Carolina, Etima, Monica, Fernandes, Alexandre, Fernandez, Maite, Fitzgerald, Felicity, Flynn, Jacquie, Ford, Deborah, Fortuny Guasch, Claudia, Foster, Caroline, Fourie, George, Fourie, Yolandie, Foxall, Sophie, Frank, Derusha, Gandhi, Kate, Garcia, India, Gartner, Kathleen, Gasa, Joshua, Gasa, Gugu, Giaquinto, Carlo, Gibb, Diana M., Gomez Rico, Coral, Gomez-Pena, Daniel, Gondo, Secrecy, Goodman, Anna, Gorreti Nakalema, Maria, Gozhora, Winnie, Greetanukroh, Pisut, Gregorio Maranon, Biobanco, Grossele, Tiziana, Gwande, Shamiso, Gwaze, Tapiwa, Gwenzi, Tsitsi, Hakim, James, Hakiza, Emmanuel, Kaka, Abdul Hamid, Harley, Ashley, Isaacs, Mornay, Isabirye, Richard, Ishemunyoro, Wilber, Jacobs, Tom, Jafta, Lungile, Jamil, Nasir, Janse van Rensburg, Anita Janse, Jeaven, Vinesh, Mellado Peña, Maria José, Jourdain, Gonzague, Juliet, Katabalwa, Jumpimai, Thidarat, Junkaew, Raungwit, Jupimai, Thidarat, Kaahwa, Winfred, Kabasonga, Mildred, Kaboggoza, Olivia, Kadhuba, Rose Jacqueline, Kaewbundit, Ampika, Kaewmamueng, Kanyanee, Kafufu, Bosco, Kakayi, Brenda, Kamboua, Phakamas, Kanjanavanit, Suparat, Kasangaki, Gladys, Kasipong, Naruporn, Kasozi, Miriam, Kataike, Hajira, Katemba, Chrispus, Kaudha, Elizabeth, Kekane, Nkata, Kekitiinwa, Adeodata R., Keminyeto, Edridah, Khamduang, Woottichai, Khamjakkaew, Warunee, Khamkon, Jiraporn, Khannak, Sasipass, Khatngam, Orapin, Khayanchoomnoom, Tassawan, Khumalo, Busi, Khunene, Mirriam, Khusuwan, Suwimon, Kibalama, Phionah, Kibenge, Robinah, Kirabira, Anthony, Kityo, Cissy M., Kiyimba, Lameck, Klein, Nigel, Klinprung, Soraya, Kobbe, Robin, Kobusingye, Olivia, Kobusungye, Josephine, Kongponoi, Areerat, Königs, Christoph, Koole, Olivier, Kouakam, Christelle, Krueduangkam, Nitinart, Kruenual, Namthip, Kunjaroenrut, Nuananong, Kyambadde, Raymonds, Kyobutungi, Priscilla, Kyomuhendo, Flavia, Kyomukama, Erinah, Lakha, Reshma, Langa, Cleopatra, Laomanit, Laddawan, Lebotsa, Emily, Leenasirimakul, Prattana, Lekku, Lawrence, Lensen, Sarah, Leroy, Valériane, Li, Jin, Liberty, Afaaf, Limplertjareanwanich, Juthamas, Little, Emma, Lugemwa, Abbas, Lutalo, Ezra, Jimenez, Jose Luis, Lyall, Hermione, MacDonald, Candice, Machache, Gladness, Madlala, Penelope, Madonsela, Tryphina, Maduna, Nomfundo, Maena, Joel, Mahanontharit, Apicha, Makanga, Collin, Makola, Candice, Makumbi, Shafic, Malgraaf, Lucille, Mamiane, Angelous, Mantkowski, Felicia, Mapfumo, Wendy, Marques, Laura, Mugagga, Agnes Mary, Maseko, Lindiwe, Masienyane, Tshepiso, Mathiba, Ruth, Matimba, Farai, Mawlana, Sajeeda, Mayanja, Emmanuel, Mayat, Fatima, Mbabazi, Ritah, Mbadaliga, Nokuthula, Mbasani, Faith, McClaughlin, Kathleen, McIlleron, Helen, Meethaisong, Watchara, Mendez Garcia, Patricia, Miwanda, Annet, Miranda, Carlota, Mkhize, Siphiwe, Mmolawa, Kgosimang, Mngqibisa, Rosie, Mohamed, Fatima, Moloantoa, Tumelo, Monametsi, Maletsatsi, Montero, Samuel, Moore, Cecilia L., Mosia, Rejoice, Moyo, Columbus, Mthethwa, Mumsy, Mudzingwa, Shepherd, Mudzviti, Tawona, Mujuru, Hilda, Mujyambere, Emmanuel, Mukanganiki, Trust, Mukisa Williams, Cynthia, Mulder, Mark, Mulima, Disan, Mulindwa, Alice, Mumbiro, Vivian, Mupambireyi, Zivai, Murciano Cabeza, Alba, Murungi, Herbert, Murungu, Dorothy, Musarurwa, Sandra, Musiime, Victor, Musiime, Alex V., Musisi, Maria, Musoke, Philippa, Musoke Nakirya, Barbara, Musoro, Godfrey, Musumba, Sharif, Mustafa, Sobia, Mutsai, Shirley, Mwesigwa Rubondo, Phyllis, Naabalamba, Mariam, Nagawa, Immaculate, Naidoo, Allemah, Nakabuye, Shamim, Nakabuye, Sarah, Nakalanzi, Sarah, Nalubwama, Justine, Nalugo, Annet, Nalusiba, Stella, Namajja, Clementine, Namanda, Sylvia, Namayanja, Paula, Nambi, Esther, Namuddu, Rachael Kikabi, Namukwaya, Stella, Namuli, Florence, Namusanje, Josephine, Namwanje, Rosemary, Nanan-kanjee, Anusha, Nanduudu, Annet, Nankunda, Charity, Baddokwaya, Joanita Nankya, Nannungi, Maria, Nansamba, Winnie, Nanthapisal, Kesdao, Nanyonjo, Juliet, Na-Rajsima, Sathaporn, Nasaazi, Claire, Nascimento, Helena, Nastouli, Eleni, Songtaweesin, Wipaporn Natalie, Nathoo, Kusum, Natuhurira, Ian, Nazzinda, Rashidah, Ncgaba, Thabisa, Ndigendawani, Milly, Ndlovu, Makhosonke, Nentsa, Georgina, Ngampiyaskul, Chaiwat, Ngcobo, Ntombenhle, Ngo Giang Huong, Nicole, Ngwaru, Pia, Nhema, Ruth, Ninsiima, Emily, Ninsiima, Gloria, Nkalo Phiri, Misheck, Noguera Julian, Antoni, Nolan, Monica, Noppakaorattanamanee, Thornthun, Nsibuka Kisekka, Muzamil, Nsirim, Eniola, Nundlal, Rashina, Nunes, Rosita, Nyantsa, Lungile, Nyati, Mandisa, O'Riordan, Sean, Ocitti Labeja, Paul, Odoch, Denis, Oguntimehin, Rachel, Ojok, Martin, Onen, Geoffrey, Orange, Wilma, Ounchanum, Pradthana, Ouma, Benson, Padrao, Andreia, Pako, Deborah, Parker, Anna, Pasko-Szcech, Malgorzata, Patel, Reena, Peongjakta, Rukchanok, Petpranee, Turian, Phillips, Tasmin, Philps, Jackie, Picault, Laura, Pieterse, Sonja, Pinheiro, Helena, Pongprapass, Supawadee, Pozniak, Anton, Prendergast, Andrew, Prieto Tato, Luis, Puangmalai, Patcharee, Puthanakit, Thanyawee, Rakgokong, Modiehi, Ramos, Helena, Ramsagar, Nastassja, Rau, Cornelius, Riault, Yoann, Rojo Conejo, Pablo, Clark, Basiimwa Roy, Rubanga, Eddie, Rubinga, Baker, Ruklao, Chutima, Runarassamee, Pattira, Rutebarika, Diana Antonia, Saenjum, Chalermpong, Saewtrakool, Chayakorn, Saidi, Yacine, Sainz Costa, Talia, Saisaengjan, Chutima, Sakwa, Rebecca, Sarfati, Tatiana, Sbisi, Noshalaza, Scheppers, Dihedile, Schultze-Strasser, Stephan, Schulze-Sturm, Ulf, Scott, Karen, Seeley, Janet, Serunjogi, Robert, Sewnarain, Leora, Shakeshaft, Clare, Sidhoo, Subashinie, Shibemba, Mercy, Shingadia, Delane, Singh, Sheleika, Sirirungsi, Wasna, Sithebe, Sibongile, Smit, Theresa, Smith, Kurt, Smuts, Marlize, Spyer, Moira, Sripaoraya, Worathip, Srirompotong, Ussanee, Srisuk, Warunee, Ssenyonga, Mark, Sudsaard, Patamawadee, Sukrakanchana, Praornsuda, Tearsansern, Pathanee, Teixeira, Carla, Than-in-at, Kanchana, Thapwai, Thitiwat, Thaweesombat, Yupawan, Thewsoongnoen, Jutarat, Thiébaut, Rodolphe, Thomason, Margaret, Thrasyvoulou, Laura, Thungkham, Khanungnit, Tikabibamu, Judith, Tinago, Gloria, Trairat, Ketmookda, Tudor-Williams, Gareth, Tukamushaba, Mercy, Tukwasibwe, Deogratiuos, Tumusiime, Julius, Tuna, Joana, Turkova, Anna, Turner, Rebecca, Udomvised, Arttasid, Vadee, Aasia, Van Huyssteen, Hesti, Van Looy, Nadine, Variava, Ebrahim, Vaughan-Gordon, Yvonne, Vecchia, Giulio, Violari, Avy, Vowden, Richard, Waalewijn, Hylke, Wampamba, Rebecca, Welch, Steve, Weller, Ian, Weza, Sibusisiwe, White, Ellen, White, Ian, Widuch, Kaja, Wilkes, Helen, Wimonklang, Sookpanee, Wynne, Ben, Yingyong, Pacharaporn, Nakawungu, Zaam Zinda, and Zuidewind, Peter
- The Lancet HIV; September 2022, Vol. 9 Issue: 9 pe638-e648, 11p
- Abstract
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Young children living with HIV have few treatment options. We aimed to assess the efficacy and safety of dolutegravir-based antiretroviral therapy (ART) in children weighing between 3 kg and less than 14 kg.
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Chang, Amy, Chiang, Teresa PY, Alejo, Jennifer L, Mitchell, Jonathan, Kim, Jake D, Abedon, Aura T, Avery, Robin K, Tobian, Aaron AR, Massie, Allan B, Levan, Macey L, Warren, Daniel S, Garonzik-Wang, Jacqueline M, Segev, Dorry L, and Werbel, William A
- Transplantation; September 2022, Vol. 106 Issue: 9, Number 9 Supplement 1 pS3-S3, 1p
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Chiang, Teresa Po-Yu, Alejo, Jennifer L, Mitchell, Jonathan, Kim, Jake D, Abedon, Aura T, Karaba, Andrew H, Thomas, Letitia, Levan, Macey L, Garonzik-Wang, Jacqueline M, Avery, Robin K, Pekosz, Andrew, Clarke, William A, Warren, Daniel S, Tobian, Aaron AR, Massie, Allan B, Segev, Dorry L, and Werbel, William A
- Transplantation; September 2022, Vol. 106 Issue: 9, Number 9 Supplement 1 pS71-S72, 2p
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Chang, Amy, Strauss, Alexandra T, Alejo, Jennifer L, Chiang, Teresa PY, Hernandez, Nicole F, Zeiser, Laura B, Boyarsky, Brian J, Avery, Robin K, Tobian, Aaron AR, Levan, Macey L, Warren, Daniel S, Massie, Allan B, Garonzik-Wang, Jacqueline M, Segev, Dorry L, and Werbel, William A
- Transplantation; September 2022, Vol. 106 Issue: 9, Number 9 Supplement 1 pS262-S263, 2p
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Alejo, Jennifer, Chiang, Teresa PY, Mitchell, Jonathan, Kim, Jake D, Abedon, Aura T, Avery, Robin K, Tobian, Aaron AR, Garonzik-Wang, Jacqueline M, Warren, Daniel S, Segev, Dorry L, Werbel, William A, and Bae, Sunjae
- Transplantation; September 2022, Vol. 106 Issue: 9, Number 9 Supplement 1 pS263-S264, 2p
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Tran, Khanh Bao, Lang, Justin J, Compton, Kelly, Xu, Rixing, Acheson, Alistair R, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Penberthy, Louise, Aali, Amirali, Abbas, Qamar, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed Abdelwahab, Abdoli, Gholamreza, Abdulkadir, Hanan Abdulkadir, Abedi, Aidin, Abegaz, Kedir Hussein, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Absalan, Abdorrahim, Abtew, Yonas Derso, Abubaker Ali, Hiwa, Abu-Gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Addison, Daniel, Addo, Isaac Yeboah, Adegboye, Oyelola A, Adesina, Miracle Ayomikun, Adnan, Mohammad, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afrin, Sumia, Afzal, Muhammad Sohail, Aggarwal, Manik, Ahinkorah, Bright Opoku, Ahmad, Araz Ramazan, Ahmad, Rizwan, Ahmad, Sajjad, Ahmad, Sohail, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Aiman, Wajeeha, Ajami, Marjan, Akalu, Gizachew Taddesse, Akbarzadeh-Khiavi, Mostafa, Aklilu, Addis, Akonde, Maxwell, Akunna, Chisom Joyqueenet, Al Hamad, Hanadi, Alahdab, Fares, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alessy, Saleh Ali, Algammal, Abdelazeem M, Al-Hanawi, Mohammed Khaled, Alhassan, Robert Kaba, Ali, Beriwan Abdulqadir, Ali, Liaqat, Ali, Syed Shujait, Alimohamadi, Yousef, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Al-Maweri, Sadeq Ali Ali, Almustanyir, Sami, Alonso, Nivaldo, Alqalyoobi, Shehabaldin, Al-Raddadi, Rajaa M, Al-Rifai, Rami H Hani, Al-Sabah, Salman Khalifah, Al-Tammemi, Ala'a B, Altawalah, Haya, Alvis-Guzman, Nelson, Amare, Firehiwot, Ameyaw, Edward Kwabena, Aminian Dehkordi, Javad Javad, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderson, Jason A, Animut, Yaregal Animut, Anoushiravani, Amir, Anoushirvani, Ali Arash, Ansari-Moghaddam, Alireza, Ansha, Mustafa Geleto, Antony, Benny, Antwi, Maxwell Hubert, Anwar, Sumadi Lukman, Anwer, Razique, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Aremu, Olatunde, Argaw, Ayele Mamo, Ariffin, Hany, Aripov, Timur, Arshad, Muhammad, Artaman, Al, Arulappan, Judie, Aruleba, Raphael Taiwo, Aryannejad, Armin, Asaad, Malke, Asemahagn, Mulusew A, Asemi, Zatollah, Asghari-Jafarabadi, Mohammad, Ashraf, Tahira, Assadi, Reza, Athar, Mohammad, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Attia, Sameh, Aujayeb, Avinash, Ausloos, Marcel, Avila-Burgos, Leticia, Awedew, Atalel Fentahun, Awoke, Mamaru Ayenew, Awoke, Tewachew, Ayala Quintanilla, Beatriz Paulina, Ayana, Tegegn Mulatu, Ayen, Solomon Shitu, Azadi, Davood, Azadnajafabad, Sina, Azami-Aghdash, Saber, Azanaw, Melkalem Mamuye, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azizi, Hosein, Azzam, Ahmed Y Y, Babajani, Amirhesam, Badar, Muhammad, Badiye, Ashish D, Baghcheghi, Nayereh, Bagheri, Nader, Bagherieh, Sara, Bahadory, Saeed, Baig, Atif Amin, Baker, Jennifer L, Bakhtiari, Ahad, Bakshi, Ravleen Kaur, Banach, Maciej, Banerjee, Indrajit, Bardhan, Mainak, Barone-Adesi, Francesco, Barra, Fabio, Barrow, Amadou, Bashir, Nasir Z, Bashiri, Azadeh, Basu, Saurav, Batiha, Abdul-Monim Mohammad, Begum, Aeysha, Bekele, Alehegn Bekele, Belay, Alemayehu Sayih, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Belo, Luis, Benzian, Habib, Berhie, Alemshet Yirga, Bermudez, Amiel Nazer C, Bernabe, Eduardo, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Bharti Bhandari, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bhuyan, Soumitra S, Bibi, Sadia, Bilchut, Awraris Hailu, Bintoro, Bagas Suryo, Biondi, Antonio, Birega, Mesfin Geremaw Birega, Birhan, Habitu Eshetu, Bjørge, Tone, Blyuss, Oleg, Bodicha, Belay Boda Abule, Bolla, Srinivasa Rao, Boloor, Archith, Bosetti, Cristina, Braithwaite, Dejana, Brauer, Michael, Brenner, Hermann, Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Buchanan, Christina Maree, Bulamu, Norma B, Bustamante-Teixeira, Maria Teresa, Butt, Muhammad Hammad, Butt, Nadeem Shafique, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cámera, Luis Alberto, Cao, Chao, Cao, Yin, Carreras, Giulia, Carvalho, Márcia, Cembranel, Francieli, Cerin, Ester, Chakraborty, Promit Ananyo, Charalampous, Periklis, Chattu, Vijay Kumar, Chimed-Ochir, Odgerel, Chirinos-Caceres, Jesus Lorenzo, Cho, Daniel Youngwhan, Cho, William C S, Christopher, Devasahayam J, Chu, Dinh-Toi, Chukwu, Isaac Sunday, Cohen, Aaron J, Conde, Joao, Cortés, Sandra, Costa, Vera Marisa, Cruz-Martins, Natália, Culbreth, Garland T, Dadras, Omid, Dagnaw, Fentaw Teshome, Dahlawi, Saad M A, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Danielewicz, Anna, Dao, An Thi Minh, Darvishi Cheshmeh Soltani, Reza, Darwesh, Aso Mohammad, Das, Saswati, Davitoiu, Dragos Virgil, Davtalab Esmaeili, Elham, De la Hoz, Fernando Pio, Debela, Sisay Abebe, Dehghan, 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Ghafourifard, Mansour, Ghamari, Seyyed-Hadi, Ghasemi Nour, Mohammad, Ghassemi, Fariba, Ghimire, Ajnish, Ghith, Nermin, Gholamalizadeh, Maryam, Gholizadeh Navashenaq, Jamshid, Ghozy, Sherief, Gilani, Syed Amir, Gill, Paramjit Singh, Ginindza, Themba G, Gizaw, Abraham Tamirat T, Glasbey, James C, Godos, Justyna, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Golitaleb, Mohamad, Gorini, Giuseppe, Goulart, Bárbara Niegia Garcia, Grosso, Giuseppe, Guadie, Habtamu Alganeh, Gubari, Mohammed Ibrahim Mohialdeen, Gudayu, Temesgen Worku, Guerra, Maximiliano Ribeiro, Gunawardane, Damitha Asanga, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Gurara, Mekdes Kondale, Guta, Alemu, Habibzadeh, Parham, Haddadi Avval, Atlas, Hafezi-Nejad, Nima, Hajj Ali, Adel, Haj-Mirzaian, Arvin, Halboub, Esam S, Halimi, Aram, Halwani, Rabih, Hamadeh, Randah R, Hameed, Sajid, Hamidi, Samer, Hanif, Asif, Hariri, Sanam, Harlianto, Netanja I, Haro, Josep Maria, Hartono, Risky Kusuma, Hasaballah, Ahmed I, Hasan, S M Mahmudul, Hasani, Hamidreza, Hashemi, Seyedeh Melika, Hassan, Abbas M, Hassanipour, Soheil, Hayat, Khezar, Heidari, Golnaz, Heidari, Mohammad, Heidarymeybodi, Zahra, Herrera-Serna, Brenda Yuliana, Herteliu, Claudiu, Hezam, Kamal, Hiraike, Yuta, Hlongwa, Mbuzeleni Mbuzeleni, Holla, Ramesh, Holm, Marianne, Horita, Nobuyuki, Hoseini, Mohammad, Hossain, Md Mahbub, Hossain, Mohammad Bellal Hossain, Hosseini, Mohammad-Salar, Hosseinzadeh, Ali, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Huang, Junjie, Hugo, Fernando N, Humayun, Ayesha, Hussain, Salman, Hussein, Nawfal R, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Iftikhar, Pulwasha Maria, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Immurana, Mustapha, Innos, Kaire, Iranpour, Pooya, Irham, Lalu Muhammad, Islam, Md Shariful, Islam, Rakibul M, Islami, Farhad, Ismail, Nahlah Elkudssiah, Isola, Gaetano, Iwagami, Masao, J, Linda Merin, Jaiswal, Abhishek, 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Maryam, Keykhaei, Mohammad, Khajuria, Himanshu, Khan, Abbas, Khan, Abdul Aziz Khan, Khan, Ejaz Ahmad, Khan, Gulfaraz, Khan, Md Nuruzzaman, Khan, Moien AB, Khanali, Javad, Khatab, Khaled, Khatatbeh, Moawiah Mohammad, Khatib, Mahalaqua Nazli, Khayamzadeh, Maryam, Khayat Kashani, Hamid Reza, Khazeei Tabari, Mohammad Amin, Khezeli, Mehdi, Khodadost, Mahmoud, Kim, Min Seo, Kim, Yun Jin, Kisa, Adnan, Kisa, Sezer, Klugar, Miloslav, Klugarová, Jitka, Kolahi, Ali-Asghar, Kolkhir, Pavel, Kompani, Farzad, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Krishan, Kewal, Krishnamoorthy, Yuvaraj, Kucuk Bicer, Burcu, Kugbey, Nuworza, Kulimbet, Mukhtar, Kumar, Akshay, Kumar, G Anil, Kumar, Narinder, Kurmi, Om P, Kuttikkattu, Ambily, La Vecchia, Carlo, Lahiri, Arista, Lal, Dharmesh Kumar, Lám, Judit, Lan, Qing, Landires, Iván, Larijani, Bagher, Lasrado, Savita, Lau, Jerrald, Lauriola, Paolo, Ledda, Caterina, Lee, Sang-woong, Lee, Shaun Wen Huey, Lee, Wei-Chen, Lee, Yeong Yeh, Lee, Yo Han, Legesse, Samson Mideksa, Leigh, James, Leong, Elvynna, Li, Ming-Chieh, Lim, Stephen S, Liu, Gang, Liu, Jue, Lo, Chun-Han, Lohiya, Ayush, Lopukhov, Platon D, Lorenzovici, László, Lotfi, Mojgan, Loureiro, Joana A, Lunevicius, Raimundas, Madadizadeh, Farzan, Mafi, Ahmad R, Magdeldin, Sameh, Mahjoub, Soleiman, Mahmoodpoor, Ata, Mahmoudi, Morteza, Mahmoudimanesh, Marzieh, Mahumud, Rashidul Alam, Majeed, Azeem, Majidpoor, Jamal, Makki, Alaa, Makris, Konstantinos Christos, Malakan Rad, Elaheh, Malekpour, Mohammad-Reza, Malekzadeh, Reza, Malik, Ahmad Azam, Mallhi, Tauqeer Hussain, Mallya, Sneha Deepak, Mamun, Mohammed A, Manda, Ana Laura, Mansour-Ghanaei, Fariborz, Mansouri, Borhan, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martini, Santi, Martorell, Miquel, Masoudi, Sahar, Masoumi, Seyedeh Zahra, Matei, Clara N, Mathews, Elezebeth, Mathur, Manu Raj, Mathur, Vasundhara, McKee, Martin, Meena, Jitendra Kumar, Mehmood, Khalid, Mehrabi Nasab, Entezar, Mehrotra, Ravi, 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Nzoputam, Ogochukwu Janet, Oancea, Bogdan, Odukoya, Oluwakemi Ololade, Oghenetega, Onome Bright, Ogunsakin, Ropo Ebenezer, Oguntade, Ayodipupo Sikiru, Oh, In-Hwan, Okati-Aliabad, Hassan, Okekunle, Akinkunmi Paul, Olagunju, Andrew T, Olagunju, Tinuke O, Olakunde, Babayemi Oluwaseun, Olufadewa, Isaac Iyinoluwa, Omer, Emad, Omonisi, Abidemi E Emmanuel, Ong, Sokking, Onwujekwe, Obinna E, Orru, Hans, Otstavnov, Stanislav S, Oulhaj, Abderrahim, Oumer, Bilcha, Owopetu, Oluwatomi Funbi, Oyinloye, Babatunji Emmanuel, P A, Mahesh, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pakbin, Babak, Pakshir, Keyvan, Pakzad, Reza, Palicz, Tamás, Pana, Adrian, Pandey, Anamika, Pandey, Ashok, Pant, Suman, Pardhan, Shahina, Park, Eun-Cheol, Park, Eun-Kee, Park, Seoyeon, Patel, Jay, Pati, Siddhartha, Paudel, Rajan, Paudel, Uttam, Paun, Mihaela, Pazoki Toroudi, Hamidreza, Peng, Minjin, Pereira, Jeevan, Pereira, Renato B, Perna, Simone, Perumalsamy, Navaraj, Pestell, Richard G, Pezzani, Raffaele, Piccinelli, Cristiano, Pillay, Julian David, Piracha, Zahra Zahid, Pischon, Tobias, Postma, Maarten J, Pourabhari Langroudi, Ashkan, Pourshams, Akram, Pourtaheri, Naeimeh, Prashant, Akila, Qadir, Mirza Muhammad Fahd, Quazi Syed, Zahiruddin, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Radhakrishnan, Raghu Anekal, Radhakrishnan, Venkatraman, Raeisi, Mojtaba, Rafiee, Ata, Rafiei, Alireza, Raheem, Nasiru, Rahim, Fakher, Rahman, Md Obaidur, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Shayan, Rahmanian, Vahid, Rajai, Nazanin, Rajesh, Aashish, Ram, Pradhum, Ramezanzadeh, Kiana, Rana, Juwel, Ranabhat, Kamal, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rashedi, Sina, Rashidi, Amirfarzan, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Ratan, Zubair Ahmed, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Razeghinia, Mohammad Sadegh, Rehman, Ashfaq Ur, Rehman, Inayat ur, Reitsma, Marissa B, Renzaho, Andre M N, Rezaei, Maryam, Rezaei, Nazila, 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Omid, Shah, Pritik A, Shahabi, Saeed, Shahid, Izza, Shahrbaf, Mohammad Amin, Shahsavari, Hamid R, Shaikh, Masood Ali, Shaka, Mohammed Feyisso, Shaker, Elaheh, Shannawaz, Mohammed, Sharew, Mequannent Melaku Sharew, Sharifi, Azam, Sharifi-Rad, Javad, Sharma, Purva, Shashamo, Bereket Beyene, Sheikh, Aziz, Sheikh, Mahdi, Sheikhbahaei, Sara, Sheikhi, Rahim Ali, Sheikhy, Ali, Shepherd, Peter Robin, Shetty, Adithi, Shetty, Jeevan K, Shetty, Ranjitha S, Shibuya, Kenji, Shirkoohi, Reza, Shirzad-Aski, Hesamaddin, Shivakumar, K M, Shivalli, Siddharudha, Shivarov, Velizar, Shobeiri, Parnian, Shokri Varniab, Zahra, Shorofi, Seyed Afshin, Shrestha, Sunil, Sibhat, Migbar Mekonnen, Siddappa Malleshappa, Sudeep K, Sidemo, Negussie Boti, Silva, Diego Augusto Santos, Silva, Luís Manuel Lopes Rodrigues, Silva Julian, Guilherme, Silvestris, Nicola, Simegn, Wudneh, Singh, Achintya Dinesh, Singh, Ambrish, Singh, Garima, Singh, Harpreet, Singh, Jasvinder A, Singh, Jitendra Kumar, Singh, Paramdeep, Singh, Surjit, Sinha, Dhirendra Narain, Sinke, Abiy H, Siraj, Md Shahjahan, Sitas, Freddy, Siwal, Samarjeet Singh, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Socea, Bogdan, Soeberg, Matthew J, Sofi-Mahmudi, Ahmad, Solomon, Yonatan, Soltani-Zangbar, Mohammad Sadegh, Song, Suhang, Song, Yimeng, Sorensen, Reed J D, Soshnikov, Sergey, Sotoudeh, Houman, Sowe, Alieu, Sufiyan, Mu'awiyyah Babale, Suk, Ryan, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Saima, Sur, Daniel, Szócska, Miklós, Tabaeian, Seidamir Pasha, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabuchi, Takahiro, Tadbiri, Hooman, Taheri, Ensiyeh, Taheri, Majid, Taheri Soodejani, Moslem, Takahashi, Ken, Talaat, Iman M, Tampa, Mircea, Tan, Ker-Kan, Tat, Nathan Y, Tat, Vivian Y, Tavakoli, Ahmad, Tavakoli, Arash, Tehrani-Banihashemi, Arash, Tekalegn, Yohannes, Tesfay, Fisaha Haile, Thapar, Rekha, Thavamani, Aravind, Thoguluva Chandrasekar, Viveksandeep, Thomas, Nihal, Thomas, Nikhil Kenny, Ticoalu, Jansje Henny Vera, Tiyuri, Amir, Tollosa, Daniel Nigusse, Topor-Madry, Roman, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Mai Thi Ngoc, Tripathy, Jaya Prasad, Ukke, Gebresilasea Gendisha, Ullah, Irfan, Ullah, Saif, Ullah, Sana, Unnikrishnan, Bhaskaran, Vacante, Marco, Vaezi, Maryam, Valadan Tahbaz, Sahel, Valdez, Pascual R, Vardavas, Constantine, Varthya, Shoban Babu, Vaziri, Siavash, Velazquez, Diana Zuleika, Veroux, Massimiliano, Villeneuve, Paul J, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vo, Bay, Vu, Linh Gia, Wadood, Abdul Wadood, Waheed, Yasir, Walde, Mandaras Tariku, Wamai, Richard G, Wang, Cong, Wang, Fang, Wang, Ning, Wang, Yu, Ward, Paul, Waris, Abdul, Westerman, Ronny, Wickramasinghe, Nuwan Darshana, Woldemariam, Melat, Woldu, Berhanu, Xiao, Hong, Xu, Suowen, Xu, Xiaoyue, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Yang, Lin, Yazdanpanah, Fereshteh, Yeshaw, Yigizie, Yismaw, Yazachew, Yonemoto, Naohiro, Younis, Mustafa Z, Yousefi, Zabihollah, Yousefian, Fatemeh, Yu, Chuanhua, Yu, Yong, Yunusa, Ismaeel, Zahir, Mazyar, Zaki, Nazar, Zaman, Burhan Abdullah, Zangiabadian, Moein, Zare, Fariba, Zare, Iman, Zareshahrabadi, Zahra, Zarrintan, Armin, Zastrozhin, Mikhail Sergeevich, Zeineddine, Mohammad A, Zhang, Dongyu, Zhang, Jianrong, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhou, Linghui, Zodpey, Sanjay, Zoladl, Mohammad, Vos, Theo, Hay, Simon I, Force, Lisa M, and Murray, Christopher J L
- The Lancet; August 2022, Vol. 400 Issue: 10352 p563-591, 29p
- Abstract
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Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally.
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Patel Y, Shin J, Abé C, Agartz I, Alloza C, Alnæs D, Ambrogi S, Antonucci LA, Arango C, Arolt V, Auzias G, Ayesa-Arriola R, Banaj N, Banaschewski T, Bandeira C, Başgöze Z, Cupertino RB, Bau CHD, Bauer J, Baumeister S, Bernardoni F, Bertolino A, Bonnin CDM, Brandeis D, Brem S, Bruggemann J, Bülow R, Bustillo JR, Calderoni S, Calvo R, Canales-Rodríguez EJ, Cannon DM, Carmona S, Carr VJ, Catts SV, Chenji S, Chew QH, Coghill D, Connolly CG, Conzelmann A, Craven AR, Crespo-Facorro B, Cullen K, Dahl A, Dannlowski U, Davey CG, Deruelle C, Díaz-Caneja CM, Dohm K, Ehrlich S, Epstein J, Erwin-Grabner T, Eyler LT, Fedor J, Fitzgerald J, Foran W, Ford JM, Fortea L, Fuentes-Claramonte P, Fullerton J, Furlong L, Gallagher L, Gao B, Gao S, Goikolea JM, Gotlib I, Goya-Maldonado R, Grabe HJ, Green M, Grevet EH, Groenewold NA, Grotegerd D, Gruber O, Haavik J, Hahn T, Harrison BJ, Heindel W, Henskens F, Heslenfeld DJ, Hilland E, Hoekstra PJ, Hohmann S, Holz N, Howells FM, Ipser JC, Jahanshad N, Jakobi B, Jansen A, Janssen J, Jonassen R, Kaiser A, Kaleda V, Karantonis J, King JA, Kircher T, Kochunov P, Koopowitz SM, Landén M, Landrø NI, Lawrie S, Lebedeva I, Luna B, Lundervold AJ, MacMaster FP, Maglanoc LA, Mathalon DH, McDonald C, McIntosh A, Meinert S, Michie PT, Mitchell P, Moreno-Alcázar A, Mowry B, Muratori F, Nabulsi L, Nenadić I, O'Gorman Tuura R, Oosterlaan J, Overs B, Pantelis C, Parellada M, Pariente JC, Pauli P, Pergola G, Piarulli FM, Picon F, Piras F, Pomarol-Clotet E, Pretus C, Quidé Y, Radua J, Ramos-Quiroga JA, Rasser PE, Reif A, Retico A, Roberts G, Rossell S, Rovaris DL, Rubia K, Sacchet M, Salavert J, Salvador R, Sarró S, Sawa A, Schall U, Scott R, Selvaggi P, Silk T, Sim K, Skoch A, Spalletta G, Spaniel F, Stein DJ, Steinsträter O, Stolicyn A, Takayanagi Y, Tamm L, Tavares M, Teumer A, Thiel K, Thomopoulos SI, Tomecek D, Tomyshev AS, Tordesillas-Gutiérrez D, Tosetti M, Uhlmann A, Van Rheenen T, Vazquez-Bourgón J, Vernooij MW, Vieta E, Vilarroya O, Weickert C, Weickert T, Westlye LT, Whalley H, Willinger D, Winter A, Wittfeld K, Yang TT, Yoncheva Y, Zijlmans JL, Hoogman M, Franke B, van Rooij D, Buitelaar J, Ching CRK, Andreassen OA, Pozzi E, Veltman D, Schmaal L, van Erp TGM, Turner J, Castellanos FX, Pausova Z, Thompson P, and Paus T
Biological psychiatry [Biol Psychiatry] 2022 Aug 15; Vol. 92 (4), pp. 299-313. Date of Electronic Publication: 2022 Mar 04.
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Cerebral Cortex, Child, Female, Humans, Infant, Newborn, Magnetic Resonance Imaging methods, Pregnancy, Attention Deficit Disorder with Hyperactivity, Autism Spectrum Disorder genetics, Autism Spectrum Disorder pathology, Bipolar Disorder, Depressive Disorder, Major pathology, and Premature Birth pathology
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Background: Morphology of the human cerebral cortex differs across psychiatric disorders, with neurobiology and developmental origins mostly undetermined. Deviations in the tangential growth of the cerebral cortex during pre/perinatal periods may be reflected in individual variations in cortical surface area later in life.
Methods: Interregional profiles of group differences in surface area between cases and controls were generated using T1-weighted magnetic resonance imaging from 27,359 individuals including those with attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depressive disorder, schizophrenia, and high general psychopathology (through the Child Behavior Checklist). Similarity of interregional profiles of group differences in surface area and prenatal cell-specific gene expression was assessed.
Results: Across the 11 cortical regions, group differences in cortical area for attention-deficit/hyperactivity disorder, schizophrenia, and Child Behavior Checklist were dominant in multimodal association cortices. The same interregional profiles were also associated with interregional profiles of (prenatal) gene expression specific to proliferative cells, namely radial glia and intermediate progenitor cells (greater expression, larger difference), as well as differentiated cells, namely excitatory neurons and endothelial and mural cells (greater expression, smaller difference). Finally, these cell types were implicated in known pre/perinatal risk factors for psychosis. Genes coexpressed with radial glia were enriched with genes implicated in congenital abnormalities, birth weight, hypoxia, and starvation. Genes coexpressed with endothelial and mural genes were enriched with genes associated with maternal hypertension and preterm birth.
Conclusions: Our findings support a neurodevelopmental model of vulnerability to mental illness whereby prenatal risk factors acting through cell-specific processes lead to deviations from typical brain development during pregnancy.
(Copyright © 2022 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.)
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47. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. [2022]
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Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Lee WJ, Hsiung CA, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Schönherr S, Forer L, Scholz M, Galesloot TE, Bradfield JP, Ruotsalainen SE, Daw EW, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Le P, Feitosa MF, Wojczynski MK, Hemerich D, Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Noah TL, Verma A, Slieker RC, Lo KS, Zilhao NR, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Emmel C, Schmidt B, Smyth LJ, Cañadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kähönen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Sankareswaran A, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Prasad G, Lorés-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Morgan A, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas MP, Vaccargiu S, van der Most PJ, Pitkänen N, Cade BE, van der Laan SW, Chitrala KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikäinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, He KY, Tang H, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jäger S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Kähönen M, Pérusse L, Bouchard C, Tönjes A, Ida Chen YD, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellström D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Zimmermann ME, Völzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Peyser PA, Kato N, Schulze MB, Girotto G, Böger CA, Jung B, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Tusié-Luna T, Aguilar-Salinas CA, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Walker M, Scott LJ, Koistinen HA, Chandak GR, Mercader JM, Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam RM, Lehtimäki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jöckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Lu F, Hishigaki H, Lin X, März W, Gudnason V, Tardif JC, Lettre G, T Hart LM, Elders PJM, Rader DJ, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP, Rotimi CN, Christensen K, Ripatti S, Widén E, Hakonarson H, Grant SFA, Kiemeney L, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, Männikkö M, Jarvelin MR, Kutalik Z, Francesco C, Mook-Kanamori DO, Willems van Dijk K, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Huey-Herng Sheu W, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, de Geus EJC, Cupples LA, van Meurs JBJ, Ikram A, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Tuomilehto J, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A, Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, Åsvold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen YE, Ho YL, Lynch JA, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson P, Mohlke KL, Frayling TM, Hirschhorn JN, Kathiresan S, Boehnke M, Struan Grant, Natarajan P, Sun YV, Morris AP, Deloukas P, Peloso G, Assimes TL, Willer CJ, Zhu X, and Brown CD
American journal of human genetics [Am J Hum Genet] 2022 Aug 04; Vol. 109 (8), pp. 1366-1387.
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Chromatin genetics, Genomics, Humans, Lipids genetics, Genome-Wide Association Study, and Polymorphism, Single Nucleotide genetics
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A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of functional genomic datasets to discover regulatory mechanisms underlying lipid associations. We first prioritize lipid-associated genes with expression quantitative trait locus (eQTL) colocalizations and then add chromatin interaction data to narrow the search for functional genes. Polygenic enrichment analysis across 697 annotations from a host of tissues and cell types confirms the central role of the liver in lipid levels and highlights the selective enrichment of adipose-specific chromatin marks in high-density lipoprotein cholesterol and triglycerides. Overlapping transcription factor (TF) binding sites with lipid-associated loci identifies TFs relevant in lipid biology. In addition, we present an integrative framework to prioritize causal variants at GWAS loci, producing a comprehensive list of candidate causal genes and variants with multiple layers of functional evidence. We highlight two of the prioritized genes, CREBRF and RRBP1, which show convergent evidence across functional datasets supporting their roles in lipid biology.
Competing Interests: Declaration of interests G.C.-P. is currently an employee of 23andMe Inc. M.J.C. is the Chief Scientist for Genomics England, a UK Government company. B.M. Psaty serves on the steering committee of the Yale Open Data Access Project funded by Johnson & Johnson. G. Thorleifsson, A.H., D.F.G., H. Holm, U.T., and K.S. are employees of deCODE/Amgen Inc. V.S. has received honoraria for consultations from Novo Nordisk and Sanofi and has an ongoing research collaboration with Bayer Ltd. M. McCarthy has served on advisory panels for Pfizer, NovoNordisk, and Zoe Global and has received honoraria from Merck, Pfizer, Novo Nordisk, and Eli Lilly and research funding from Abbvie, Astra Zeneca, Boehringer Ingelheim, Eli Lilly, Janssen, Merck, NovoNordisk, Pfizer, Roche, Sanofi Aventis, Servier, and Takeda. M. McCarthy and A. Mahajan are employees of Genentech and holders of Roche stock. M.S. receives funding from Pfizer Inc. for a project unrelated to this work. M.E.K. is employed by SYNLAB MVZ Mannheim GmbH. W.M. has received grants from Siemens Healthineers, grants and personal fees from Aegerion Pharmaceuticals, grants and personal fees from AMGEN, grants from Astrazeneca, grants and personal fees from Sanofi, grants and personal fees from Alexion Pharmaceuticals, grants and personal fees from BASF, grants and personal fees from Abbott Diagnostics, grants and personal fees from Numares AG, grants and personal fees from Berlin-Chemie, grants and personal fees from Akzea Therapeutics, grants from Bayer Vital GmbH , grants from bestbion dx GmbH, grants from Boehringer Ingelheim Pharma GmbH Co KG, grants from Immundiagnostik GmbH, grants from Merck Chemicals GmbH, grants from MSD Sharp and Dohme GmbH, grants from Novartis Pharma GmbH, grants from Olink Proteomics, and other from Synlab Holding Deutschland GmbH, all outside the submitted work. A.V.K. has served as a consultant to Sanofi, Medicines Company, Maze Pharmaceuticals, Navitor Pharmaceuticals, Verve Therapeutics, Amgen, and Color Genomics; received speaking fees from Illumina and the Novartis Institute for Biomedical Research; received sponsored research agreements from the Novartis Institute for Biomedical Research and IBM Research, and reports a patent related to a genetic risk predictor (20190017119). S. Kathiresan is an employee of Verve Therapeutics and holds equity in Verve Therapeutics, Maze Therapeutics, Catabasis, and San Therapeutics. He is a member of the scientific advisory boards for Regeneron Genetics Center and Corvidia Therapeutics; he has served as a consultant for Acceleron, Eli Lilly, Novartis, Merck, Novo Nordisk, Novo Ventures, Ionis, Alnylam, Aegerion, Haug Partners, Noble Insights, Leerink Partners, Bayer Healthcare, Illumina, Color Genomics, MedGenome, Quest, and Medscape; and he reports patents related to a method of identifying and treating a person having a predisposition to or afflicted with cardiometabolic disease (20180010185) and a genetics risk predictor (20190017119). D.K. accepts consulting fees from Regeneron Pharmaceuticals. D.O.M.-K. is a part-time clinical research consultant for Metabolon, Inc. D. Saleheen has received support from the British Heart Foundation, Pfizer, Regeneron, Genentech, and Eli Lilly pharmaceuticals. P.N. reports investigator-initated grants from Amgen, Apple, AstraZeneca, Boston Scientific, and Novartis, personal fees from Apple, AstraZeneca, Blackstone Life Sciences, Foresite Labs, Novartis, Roche / Genentech, is a co-founder of TenSixteen Bio, is a scientific advisory board member of Esperion Therapeutics, geneXwell, and TenSixteen Bio, and spousal employment at Vertex, all unrelated to the present work. The spouse of C.J.W. is employed by Regeneron.
(Copyright © 2022 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.)
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González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, Shen Y, Goland RS, Leibel RL, and Egli D
Communications biology [Commun Biol] 2022 Aug 02; Vol. 5 (1), pp. 779. Date of Electronic Publication: 2022 Aug 02.
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Calcium metabolism, Hepatocyte Nuclear Factor 1-alpha genetics, Hepatocyte Nuclear Factor 1-alpha metabolism, Humans, Insulin, Regular, Human, Stem Cells metabolism, Synaptotagmins, Diabetes Mellitus, Type 2 genetics, and Insulin metabolism
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Mutations in HNF1A cause Maturity Onset Diabetes of the Young (HNF1A-MODY). To understand mechanisms of β-cell dysfunction, we generated stem cell-derived pancreatic endocrine cells with hypomorphic mutations in HNF1A. HNF1A-deficient β-cells display impaired basal and glucose stimulated-insulin secretion, reduced intracellular calcium levels in association with a reduction in CACNA1A expression, and accumulation of abnormal insulin granules in association with SYT13 down-regulation. Knockout of CACNA1A and SYT13 reproduce the relevant phenotypes. In HNF1A deficient β-cells, glibenclamide, a sulfonylurea drug used in the treatment of HNF1A-MODY patients, increases intracellular calcium, and restores insulin secretion. While insulin secretion defects are constitutive in β-cells null for HNF1A, β-cells heterozygous for hypomorphic HNF1A (R200Q) mutations lose the ability to secrete insulin gradually; this phenotype is prevented by correction of the mutation. Our studies illuminate the molecular basis for the efficacy of treatment of HNF1A-MODY with sulfonylureas, and suggest promise for the use of cell therapies.
(© 2022. The Author(s).)
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Martinez VA, Betts RK, Scruth EA, Buckley JD, Cadiz VR, Bertrand LD, Paulson SS, Dummett BA, Abhyankar SS, Reyes VM, Hatton JR, Sulit R, and Liu VX
Joint Commission journal on quality and patient safety [Jt Comm J Qual Patient Saf] 2022 Aug; Vol. 48 (8), pp. 370-375.
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Adult, Artificial Intelligence, Hospitals, Humans, Inpatients, Monitoring, Physiologic, and Clinical Deterioration
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Background: In-hospital deterioration among ward patients is associated with substantially increased adverse outcome rates. In 2013 Kaiser Permanente Northern California (KPNC) developed and implemented a predictive analytics-driven program, Advance Alert Monitor (AAM), to improve early detection and intervention for in-hospital deterioration. The AAM predictive model is designed to give clinicians 12 hours of lead time before clinical deterioration, permitting early detection and a patient goals-concordant response to prevent worsening.
Design of the Aam Intervention: Across the 21 hospitals of the KPNC integrated health care delivery system, AAM analyzes electronic health record (EHR) data for patients in medical/surgical and telemetry units 24 hours a day, 7 days a week. Patients identified as high risk by the AAM algorithm trigger an alert for a regional team of experienced critical care virtual quality nurse consultants (VQNCs), who then cascade validated, actionable information to rapid response team (RRT) nurses at local hospitals. RRT nurses conduct bedside assessments of at-risk patients and formulate interdisciplinary clinical responses with hospital-based physicians, bedside nurses, and supportive care teams to ensure a well-defined escalation plan that includes clarification of the patients' goals of care.
Success of the Intervention: Since 2019 the AAM program has been implemented at all 21 KPNC hospitals. The use of predictive modeling embedded within the EHR to identify high-risk patients has produced the standardization of monitoring workflows, clinical rescue protocols, and coordination to ensure that care is consistent with patients' individual goals of care. An evaluation of the program, using a staggered deployment sequence over 19 hospitals, demonstrates that the AAM program is associated with statistically significant decreases in mortality (9.8% vs. 14.4%), hospital length of stay, and ICU length of stay. Statistical analyses estimated that more than 500 deaths were prevented each year with the AAM program.
Lessons Learned: Unlocking the potential of predictive modeling in the EHR is the first step toward realizing the promise of artificial intelligence/machine learning (AI/ML) to improve health outcomes. The AAM program leveraged predictive analytics to produce highly reliable care by identifying at-risk patients, preventing deterioration, and reducing adverse outcomes and can be used as a model for how clinical decision support and inpatient population management can effectively improve care.
(Copyright © 2022 The Joint Commission. Published by Elsevier Inc. All rights reserved.)
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Chang A, Chiang TP, Kim JD, Mitchell J, Alejo JL, Jefferis AA, Avery RK, Tobian AAR, Levan ML, Warren DS, Garonzik-Wang JM, Massie AB, Segev DL, and Werbel WA
Clinical transplantation [Clin Transplant] 2022 Aug; Vol. 36 (8), pp. e14738. Date of Electronic Publication: 2022 Jun 14.
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2019-nCoV Vaccine mRNA-1273, Antibodies, Viral, BNT162 Vaccine, Humans, Transplant Recipients, Influenza Vaccines, and Organ Transplantation adverse effects
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Strauss AT, Chang A, Alejo JL, Chiang TP, Hernandez NF, Zeiser LB, Boyarsky BJ, Avery RK, Tobian AAR, Levan ML, Warren DS, Massie AB, Garonzik-Wang JM, Segev DL, and Werbel WA
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society [Liver Transpl] 2022 Aug; Vol. 28 (8), pp. 1393-1396. Date of Electronic Publication: 2022 May 09.
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Antibodies, Viral, Antibody Formation, Humans, RNA, Messenger, SARS-CoV-2 genetics, Transplant Recipients, Vaccination, COVID-19 prevention control, and Liver Transplantation adverse effects
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Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Joshua, Abbas, Kasim, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abbott, Alison, Abdallah, Nabeel, Abdelaziz, Ammar, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Audrey, Abdul, Basir, Abdul, Siddiqui, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdullah, Abdullah, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Ul Amna, Abeer, Abel, Lynn, Abernethy, Katrina, Abeywickrema, Movin, Abhinaya, Chandra, Abidin, Affyarsyah, Aboaba, Adebanke, Aboagye-Odei, Abigail, Aboelela, Heba, Abo-Leyah, Hani, Abouelela, Karim, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abousamra, Ahmed, Abouzaid, Mona, Abraham, Miriam, Abraham, Tizzy, Abraheem, Abraheem, Abrams, Judith, Abrams, Rebecca, Abu, Hyacinth-John, Abu-Arafeh, Ahmed, Abubacker, Syed Mohamed, Abung, Akata, Abusamra, Yousuf, Aceampong, Yaa, Achara, Amaka, Acharya, 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Campbell, Hilary, Campbell, Jonathan, Campbell, Karen, Campbell, Marion, Campbell, Mark, Campbell, Rachael, Campbell, Robyn, Campbell, Wynny, Campbell Hewson, Quentin, Camsooksai, Julie, Canclini, Lisa, Candido, Shaula Mae, Candlish, Janie, Caneja, Cielito, Cann, Alexandra, Cann, Johnathon, Cannan, Ruby, Cannon, Abigail, Cannon, Emma, Cannon, Michael, Cannon, Petra, Cannons, Vivienne, Canonizado, Ebnier, Cantliff, Jane, Caplin, Ben, Capocci, Santino, Caponi, Noemi, Capp, Angelika, Capstick, Richard, Capstick, Thomas, Caraenache, Catalin, Card, Aimee, Cardwell, Mary, Carey, Charles, Carey, Rachel, Carley, Simon, Carlin, Ffion, Carlin, Tammy, Carmichael, Samantha, Carmody, Margaret, Carnahan, Mandy, Caroline, Charlotte, Carpenter, Jodi, Carr, Sharon, Carrasco, Anna, Carrington, Zoe, Carroll, Amy, Carroll, Anne, Carroll, Paul, Carson, Rachel, Cart, Cindy, Carter, Emma, Carter, Jonathan, Carter, Michael, Carter, Natasha, Carter, Paul, Carter, Penny, Cartwright, Douglas, Cartwright, 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Cheuk, Chan, Evelyn, Chan, Jay M, Chan, Kawai, Chan, Kayen, Chan, Kimberley, Chan, Ping, Chan, Rebekah (Pui-Ching), Chan, Xin Hui S, Chandler, Chris, Chandler, Heidi, Chandler, Kim J, Chandler, Stuart, Chandler, Zoe, Chandra, Sumit, Chandran, Navin, Chandrasekaran, Badrinathan, Chang, Yvonne, Chaplin, Grace, Chaplin, Josephine, Chapman, Graeme, Chapman, John, Chapman, Katie, Chapman, Laura, Chapman, Lianne, Chapman, Matthew, Chapman, Polly, Chapman, Timothy, Chappell, Lucy, Charalambou, Amanda, Charles, Bethan, Charlton, Dianne, Charlton, Sam, Chatar, Kevin, Chatha, Calvin, Chatterton, Debra, Chaube, Ritesh, Chaudhary, Muhammad Y N, Chaudhry, Iram, Chaudhry, Zain, Chaudhuri, Nazia, Chaudhury, Muhammad, Chauhan, Anoop, Chauhan, Ruchi S, Chavasse, Alexander, Chavasse, Nicola, Chawla, Vipal, Cheater, Lindsay, Cheaveau, James, Cheeld, Charlotte, Cheeseman, Michelle, Chen, Fang, Chen, Hui Min, Chen, Terence, Cheng, Floria, Cheng, Lok Yin, Cheng, Zhihang, Chenoweth, Helen, Cheong, Chun How, Cherian, Shiney, Cherrie, Mary, Cheshire, Helen, Cheung, Chee Kay, Cheung, Elaine, Cheung, Kayan, Cheung, Michelle, Cheyne, Claire, Chhabra, Swati, Chia, Wei Ling, Chiang, Eric, Chiapparino, Angela, Chicano, Rosavic, Chikungwa, Moses, Chikwanha, Zviedzo A, Chilcott, Gemma, Chilcott, Sam, Chilvers, Alison, Chimbo, Phillipa, Chin, KokWai, Chin, Wen Jie, Chineka, Rumbidzai, Chingale, Amol, Chinonso, Ezomike, Chin-Saad, Chloe, Chirgwin, Margaret, Chisem, Heather, Chisenga, Claire, Chisholm, Catherine, Chisnall, Ben, Chiswick, Carolyn, Chita, Sunder, Chitalia, Nihil, Chiu, Matthew, Chiverton, Laura, Chivima, Brenda, Chmiel, Catherine, Choi, Soha, Choon Kon Yune, Willy, Chopra, Meena, Chopra, Michelle, Choudhary, Vandana, Choudhury, Omur, Choudhury, Sarah, Chow, Bing-Lun, Chowdhury, Mahibbur, Chowdhury, Shahid, Chrisopoulou, Angela, Christenssen, Victoria, Christian, Peter, Christides, Alexander, Christie, Fiona, Christmas, Daniel, Christoforou, Georgios, Christopherson, Thereza, Christou, Anna, Christy, Mark, Chrysostomou, Paris, Chua, Yunli, Chudgar, Dip, Chudleigh, Richard, Chukkambotla, Srikanth, Chukwu, Michael E, Chukwulobelu, Izu, Chung, Chi Yee, Church, Elaine, Church, Sara R, Churchill, David, Cianci, Nicole, Cicconi, Paola, Cinardo, Paola, Cipinova, Zdenka, Cipriano, Bessie, Clamp, Sarah, Clancy, Bridget, Clapham, Melanie, Clare, Edel, Clare, Sarbjit, Clark, Andrew, Clark, Charlotte, Clark, Diane, Clark, Emma, Clark, Felicity, Clark, Gabrielle, Clark, James, Clark, Julia, Clark, Katherine, Clark, Kaylea, Clark, Louise, Clark, Lucy, Clark, Martyn, Clark, Matthew, Clark, Nicola, Clark, Patricia, Clark, Richard, Clark, Thomas, Clark, Tonia, Clark, Zoe, Clarke, Alison, Clarke, Andrea, Clarke, Jude, Clarke, Paul, Clarke, Robert, Clarke, Roseanne, Clarke, Samantha, Clarke, Sheron, Claxton, Alleyna, Claxton, Louis, Clay, Kate, Clayton, Catherine, Clayton, Elizabeth, Clayton, Olivia, Clayton-Smith, Jill, Clearyb, Bethan, Cleaver, Chris, Cleeton, Rose, Clement, Ian, Clemente de la Torre, Carlota, Clements, Jayne, Clements, Suzanne, Clenton, Sue, Cliff, Sheryl, Clifford, Rachael, Clifford, Sarah, Clive, Amelia, Clouston, Jonathan, Clubb, Vincent, Clueit, Samantha, Clutterbuck, Lisa, Clyne, Andrea, Coakley, Michelle, Coakley, Peter G L, Cobain, Kathryn, Cochrane, Alexandra, Cochrane, Patricia, Cockayne, Laura, Cockerell, Maeve, Cockerill, Helen, Cocks, Shirley, Codling, Rachel, Coe, Adam, Coetzee, Samantha, Coey, David, Cohen, Danielle, Cohen, Jonathan, Cohen, Oliver, Cohen, David, Cohn, Mike, Coke, Louise, Coker, Olutoyin, Colbeck, Nicholas, Colbert, Roghan, Cole, Esther, Cole, Jade, Cole, Joby, Coleman, Garry, Coleman, Matt, Coleman, Nick, Coles, Holly, Colin, Macleod, Colino-Acevedo, Alicia, Colley, Julie, Collie, Kathleen, Collier, Alexandra, Collier, Danielle, Collier, Dawn, Collier, Heather, Collingwood, Terry, Collini, Paul, Collins, Emma, Collins, Jaimie, Collins, Joanne, Collins, Kayleigh, Collins, Megan, Collins, Nicola, Collins, Sally, Collins, Vicky, Collinson, Andrew, Collinson, Bernadette, Collinson, Jennifer, Collis, Matthew, Colmar, Madeleine, Colton, Hayley E, Colton, James, Colville, Katie, Colvin, Carolyn, Combes, Edward, Comer, David, Comerford, Alison, Concannon, Dónal, Condliffe, Alison, Condliffe, Robin, Connell, Emma, Connell, Lynne, Connell, Natalie, Connelly, Karen, Connolly, Gavin, Connor, Emma, Conroy, Antonia, Conroy, Kevin, Conteh, Veronica, Convery, Rory, Conway, Francesca, Conway, Grainne, Conway, Rhiannon, Conway, Robert, Conyngham, Jo-Anna, Cook, Amanda, Cook, Amber, Cook, Colette, Cook, Eloise, Cook, Gemma, Cook, Helen, Cook, Julie, Cook, Martin, Cook, Sarah, Cooke, Danielle, Cooke, Graham, Cooke, Hannah, Cooke, Justin, Cooke, Katrina, Cooke, Tim, Cooke, Vikki, Cooper, Adele, Cooper, Chris, Cooper, David, Cooper, Helen, Cooper, Jamie, Cooper, Lauren, Cooper, Nick, Cooper, Rowena, Cooray, Samantha, Cope, Thomas, Corbet, Sinead, Corbett, Carolyn, Corbishley, Ailsa, Corcoran, John, Cordell, Chris, Cordle, Jessica, Corfield, Alasdair, Corless, John, Corlett, Alison, Cornwell, Joe, Cornwell, Michael, Corogeanu, Diana, Corr, Aisling, Corredera, Mirella, Corrigan, Ruth, Corry, P, Corser, Rita, Cort, Jon, Cosgrove, Denise, Cosier, Tracey, Costa, Patricia, Costa, Telma, Coston, Charlie, Cotgrove, Susannah, Coton, Zoe, Cottam, Lisa-Jayne, Cotter, Rhiannon, Cotterill, Donna, Cotton, Caroline, Couch, George, Coulding, Martina, Coull, Andrew, Counsell, David, Counter, David, Coupland, Cherry, Courtney, Ellie, Courtney, Julia, Cousins, Rebecca, Coutts, Amanda J, Cowan, Alexander, Cowan, Elena, Cowan, Richard, Cowell, Richard, Cowen, Louise, Cowman, Steve, Cowton, Amanda, Cox, Ellie, Cox, Emma, Cox, Giles, Cox, Helen, Cox, Karina, Cox, Miriam, Coy, Karen, Cradduck-Bamford, Andrea, Craig, Hannah, Craig, Jayne, Craig, John, Craig, Victoria, Craighead, Felicity, Cramp, Matthew, Cranston, Hayley, Crasta, Sheetal S, Crause, Jacolene, Crawford, Angie, Crawford, Emma, Crawford, Isobel, Crawshaw, Sarah, Creagh-Brown, Ben, Creamer, Andrew, Creaser-Myers, Amanda, Cremona, Joanne, Cremona, Saveria, Crepet, Anna, Cresswell, Janet, Cribb, Mark, Crichton, Charles, Crilly, Declan, Crisp, Lauren, Crisp, Nikki, Crocombe, Dominic, Croft, Maria, Crooks, Jennifer, Crosby, Harriet, Cross, Elizabeth, Cross, Tim, Crothers, Amy, Crotty, Stephen, Crouch, Susan, Crow, Madeleine, Crowder, Amanda, Crowley, Kate, Crowley, Teresa, Croysdill, Rebecca, Cruickshank, Callum, Cruickshank, Conor, Cruickshank, Irena, Cruise, James, Cruz, Carina, Cruz Cervera, Trino, Cryans, Dominic, Cui, Guanguo, Cui, Helen, Cullen, Lorraine, Cummings-Fosong, Gillian, Cunliffe, Victoria, Cunningham, Neil, Cunningham, Nicola, Cupitt, Jason, Curgenven, Hollie, Curnow, Gerens, Curran, David, Curran, Simon, Currie, Craig, Currie, Jacqueline, Currie, Scarlett, Currie, Susan, Currie, Susie, Curtis, Jonathan, Curtis, Katrina, Curtis, Matthew, Curtis, Olivia, Curtis, Thomas, Cuthbertson, Rebecca, Cuthill, Jennifer, Cutler, Sean, Cutts, Sarah, Czekaj, Marta, Czylok, Patrycja, D'Souza, Shane, da Rocha, Joana, Dafalla, Mohammed, Dagens, Andrew, Daggett, Helen, Daglish, Jacqui, Dahiya, Sandeep, Dale, Anne, Dale, Katie, Dale, Michaela, Dale, Sam, Dale, Susan, Dales, Jolyon, Dalgleish, Helen, Dallow, Helen, D'aloia, Carlo, Dalton, Dermot, Dalton, Morag, Daly, Zoe, Damani, Mansi, Damm, Eleanor, Danga, Akila, Dangerfield, Joanne, Daniel, Amelia, Daniel, Priya, Daniels, Allison, Dann, Adela, Danso-Bamfo, Sandra, Darby, Suzanne, Darbyshire, Alex, Darbyshire, Janet, Dargan, Paul, Dark, Paul, Darlington, Kate, Darnell, Sarah, Darton, Tom, Darylile, Guledew, Das, Avisnata, Das, Manjusha, Das, Sukamal, Daschel, Martin, Dasgin, Joanne, Datta, Dibyendu, Daunt, Anna, Dave, Vaishali, Davenport, Emily, Davey, Mark, Davey, Miriam, Davey, Molly, David, Mini, Davidson, Alexander, Davidson, Laura, Davidson, Neil, Davidson, Richard, Davies, Albert, Davies, Alison, Davies, Amanda, Davies, Amy, Davies, Angela, Davies, Bethan, Davies, Caroline, Davies, Carolyn, Davies, Catrin, Davies, Dawn, Davies, Drew, Davies, Elaine, Davies, Elinor, Davies, Ellie, Davies, Ffyon, Davies, Gwyneth, Davies, Helen, Davies, Jennifer, Davies, Jim, Davies, Karen, Davies, Kelly, Davies, Kim, Davies, Llinos, Davies, Louisa, Davies, Matthew, Davies, Michelle, Davies, Nina, Davies, Owen, Davies, Patrick, Davies, Rachel, Davies, Rhys, Davies, Ruth, Davies, Sally, Davies, Sarah, Davies, Simon, Davies, Sue, Davis, Alison, Davis, Julie-Ann, Davis, Katherine, Davis, Peter, Davis-Cook, Andrea, Davison, Alexander, Dawe, Christine, Dawe, H, Dawkins, Mark, Dawson, Angela, Dawson, Danielle, Dawson, Elizabeth, Dawson, Joy, Dawson, Lucinda, Dawson, Mike, Dawson, Susan, Dawson, Tom, Dawson, Isla, Daxter, Andrew, Day, Andrew, Day, Jacob, Day, Jeremy N, D'Costa, Jamie, De, Parijat, De, Pradip, de Fonseka, Duneesha, de Freitas, Toni, De Pretto, Roberta, De Santana Miranda, Frederico, de Sausmarez, Eleanor, de Silva, Shanika, de Silva, Thushan, De Sousa, Jessica, De Sousa, Paulo, de Souza, James, De Souza, Phillip, De Soyza, Anthony, de Vere, Natasha, de Vos, Johannes, Deacon, Bethan, Dealing, Sharon, Dean, Anna, Dean, Julie, Dean, Katrina, Dean, Stephen, Dean, Tessa, Deane, Jill, Dear, James, Dearden, Effie, Deas, Catherine, Debbie, Samuel, Debreceni, Gabor, Deelchand, Vashist, Deeley, Matthew, Deery, Joanne, Defever, Emmanuel, Del Forno, Manuela, Dela Rosa, Arnold, De-La-Cedra, Gonzalo, Dell, Amanda, De Los Santos Dominguez, Pamela, Demetriou, Carrie, DeMets, David, Democratis, Jane, Denham, Jacqueline, Denis, Emmanuelle, Denley, Laura, Denmade, Craig, Dent, Alexandra, Dent, Kathy, Dent, Martin, Denton, Elise, Denwood, Tom, Deole, Nishigandh, Depala, Darshita, Depante, Maria, Dermody, Susan, Desai, Amisha, Desai, Asmita, Desai, Purav, Deshpande, Sanjeev, Deshpande, Vai, Devkota, Sirjana, Devkota, Usha, Devonport, Debbie, Devonport, Matthew, Dey, Prakash, Dey, Vishal, Deylami, Rogin, Dhaliwal, Kevin, Dhani, Sundip, Dhanoa, Amandeep, Dhar, Mili, Dhariwal, Ankush, Dharmasena, Dawpadee, Dhasmana, Devesh, Dhillon, Ekanjali, Dhillon, Reiss, Dhillon, Syra, Dhimal, Meghnath, Dhiru, Dipali, Dhorajiwala, Trupti, Dias, Priya, Diaz, Stephanie, Diaz-Pratt, Kayleigh, Dibas, Mohammed, Dickerson, Debbie, Dicks, Pamela, Dickson, Matt, Dickson, Stuart, Digby, J, Digpal, Ronneil, Dillane, Sean, Diment, Sarah, Dimitri, Paul, Dimitriadis, Georgios, Din, Sajeel, Dinh, Thai Ha, Dipper, Alex, Dipro, Sabiq, Dirmantaite, Laura, Dismore, Lorelle, Ditchfield, Lisa, Diver, Sarah, Diwakar, Lavanya, Diwan, Preeti, Dixon, Caroline, Dixon, Giles, Dixon, Kate, Djeugam, Brice, Dlouhy, Petr, D'Mello, Andrea, Dmitri, Paul, Dobbie, Laurence, Dobranszky Oroian, Marinela, Dobson, Charlotte, Dobson, Lee, Docherty, Marie, Dockrell, David, Dodd, Jacqueline, Dodd, James, Dodds, Jackie, Dodds, Rebecca, Dodds, Steve, Dogra, Richi, Doherty, Conor, Doherty, Erin, Doherty, Warren, Doi, Yumiko, Doig, Iain, Doke, Eleanor, Dolan, Daniel, Dolman, Mark, Dolman, Rozzie, Donald, Lisa, Donald, Katie, Donaldson, Callum, Donaldson, Christopher, Donaldson, Denise, Donaldson, Gillian, Donaldson, Kate, Donlon, Sinead, Donnachie, Joanne, Donnelly, Eilish, Donnelly, Ronan, Donnison, Phil, Donohoe, Aravindhan, Donohoe, Gemma, Donohue, Bryan, Dooks, Emma, Doonan, Reece J, Doran, Grainne, Dore, Rachael, Dorey, Kane, Dorgan, Sharon, Dos Santos, Kataryna, Dosani, Moonira, Dosanjh, Davinder, Dospinescu, Paula, Doss, Isabelle, Doudouliaki, Theonymfi, Dougherty, Andrew, Doughty, Jill, Douglas, Katie, Douse, Jonathan, Dow, Allyn, Dowden, Lucy, Dower, Michelle, Dowling, Sud, Downer, Nicola, Downes, Charlotte, Downes, Rob, Downes, Thomas, Downey, Damian, Downey, Robert, Downing, Caroline, Downs, Louise, Dowson, Simon, Dragan, Cornel, Dragos, Cristina, Drain, Maire, Drake, Chelsea, Drew, Victoria, Drewett, Olivia, Drexel, Anthony, Driscoll, Celine, Drogan, Helena, Drosos, Odysseas, Drummond, Graham, Drury, Katie, Druryk, Kay, Druyeh, Ronald, Dryburgh-Jones, Jack, Drysdale, Simon, Du Thinh, An, Dube, Hazel, Dube, Judith, Duberley, Stephen, Duckenfield, Paige K, Duckles-Leech, Hayley, Duff, Nicola, Duffield, Emma, Duffy, Heather, Duffy, Helen, Duffy, Katharine, Dufour, Lionel, Duggan, Annette, Dugh, Parveen, Duhoky, Rauand, Duignan, Janice, Dulay, Jennifer, Dummer, Simon, Duncan, Alexis, Duncan, Andrew, Duncan, Christopher, Duncan, Fullerton, Duncan, Gregory, Duncan, Holly, Duncan, Robert, Dundas, Stephanie, Dunleavy, Aileen, Dunleavy, Julia, Dunn, Alessia, Dunn, Charlotte, Dunn, Damian, Dunn, Laura, Dunn, Paul, Dunne, Charlene, Dunne, Karen, Dunning, Fiona, Dunphy, Aidan, Duraiswamy, Venkat, Duran, Beatriz, DuRand, Ingrid, Durdle, Leanne, Duric, Natalie, Durie, Alison, Durie, Emily, Durogbola, Samuel, Durojaiye, Chris, Durrans, Laura, Durrant, Katie, Durrington, Hannah, Duru, Iheukwumere, Duvnjak, Haris, Dwarakanath, Akshay, Dwarakanath, Laasya, Dwyer, Ellen, Dyar, Zara, Dyball, Claudia, Dyer, Kristyn, Dymond, Harvey, Dymond, Tom, Eades, Chris, Eadie, Lauren, Eadie, Rebekah, Eagles, Laura, Eapen, Beena, Earl, Naomi, Early, Joanne, Earwaker, Melissa, Easom, Nicholas, East, Clare, Easthope, Amy, Easton, Fraser, Easton, Jack, Easton, Patrick, Eatough, Ruth, Ebigbola, Oluwadamilola, Ebon, Martin, Eccles, Alison, Eccles, Sinan, Eddings, Chloe, Eddleston, Michael, Edgar, Maureen, Edgerley, Katharine, Edmond, Nicholas, Edmondson, Mary, Edmunds, Tracy, Edwards, Abby, Edwards, Alexandra, Edwards, Catherine, Edwards, Joy, Edwards, Kennedy, Edwards, Mandy, Edwards, Martin, Edwards, Sophie, Eedle, Jenny, Eggink, Aline, Egginton, Dawn, Eggleston, Sam, Ehiorobo, Loveth, Eisen, Sarah, Ekeowa, Ugochukwu, Ekoi, Mohamed, Ekunola, Ayomide, El Behery, Soha, Elashhar, Nagla, Elawamy, Lisa, Elbeshy, Mohamed, El-Bouzidi, Kate, Elder, Jennifer, El-Din, Mohammed, Eldridge, Emma, Eleanor, Diana, Elenwa, Uchenna, Eletu, Ibrahim, Elfar, Eman, Elgamal, Mayy M, Elgohary, Amr, Elhadi, Mohamed A A, Elia, Stellios, Elias, Jennifer, Elias, Tania, Elkaram, Nadia, Elkins, Andrew V, Ellam, Julie, Ellard, Nikki, Ellerton, Laura N, Elliot, Lucy, Elliott, Amy, Elliott, Fiona, Elliott, Kerry, Elliott, Scott, Elliott, Sian, Ellis, Annie, Ellis, Christine, Ellis, Kaytie, Ellis, Leila, Ellis, Rupert, Ellis, Tak-Yan, Ellis, Yvette, Ellwood, Alison C, Elmahdi, Rahma, Elmahi, Einas, Elmasry, Hannah-May, El-Naggar, Mohammed, Elndari, Najla, Elneima, Omer, Elokl, Mohamed, Elradi, Ahmed, Elsaadany, Mohamed, Elsayed, Mohammed A S A, El-Sayeh, Sally, El-Sbahi, Hana, Elsebaei, Mohammad, Elsefi, Tarek, El-Shakankery, Karim, Elsheikh, Alguili, El-Taweel, Hosni, Elyoussfi, Sarah, Emberey, Jonathan, Emberson, Jonathan R, Emberton, John, Emery, Anna, Emmanuel, Julian, Emmerson, Ingrid, Emms, Michael, Emond, Florence, Emonts, Marieke, Enachi, Nicu, Enenche, Dickson, Engden, Angila, English, Katy, Entwistle, Emma, Enyi, Hene, Erotocritou, Marios, Eskander, Peter, Esmail, Hanif, Essa, Fatheha, Evans, Brynach, Evans, Chris, Evans, Debra, Evans, Emrys, Evans, Gail, Evans, Gareth, Evans, Isabel, Evans, Jack, Evans, Jacqueline, Evans, Jennifer, Evans, John, Evans, Jolanta, Evans, Lisa, Evans, Lynn, Evans, Mim, Evans, Morgan, Evans, Ranoromanana, Evans, Sharon, Evans, Sian, Evans, Teriann, Evans, Tomos, Everden, Caroline, Everden, Serenydd, Every, Lynette, Evison, Hayley, Evison, Lynsey, Ezenduka, Chiamaka, Faccenda, Jacqueline, Fahel, Leila, Fahmay, Youstina, Fairbairn, Ian, Fairbairn, Sara, Fairbairn, Terry, Fairclough, Andy, Fairlie, Louise, Fairweather, Mark, Fajardo, Anne, Falcone, Naomi, Falconer, Euan, Fallon, John, Fallow, Andrea, Faluyi, David, Fancois, Victoria, Farah, Ayaan, Farah, Muna, Farah, Qayyum, Fard, Nowin Z, Fares, Leila, Farg, Amr, Farmer, Adam, Farmer, Katie, Farmery, Toni, Farnworth, Samantha, Farook, Faiyaz, Farooq, Hadia, Farooq, Sidrah, Farquhar, Fiona, Farr, Holly, Farrell, Aaron, Farrell, Barbara, Farrukh, Fayed, Farthing, James, Farzana, Syeda, Fasina, Rahmatu, Fatemi, Azam, Fatemi, Mina, Fathima, Suman, Fatimah, Nibah, Faulkner, Maria, Faust, Saul N, Favager, Clair, Fawke, Joe, Fawohunre, Sinmidele, Fazal, Abul, Fazleen, Aisthath, Fearby, Simon, Fearnley, Connie, Feben, Alex, Fedel, Federico, Fedorova, Daria, Fegan, Christopher, Felongo, Mae, Felton, Lynsey, Felton, Tim, Fenlon, Kate, Fenn, Andrea, Fennelly, Ruth, Fenner, Isabelle, Fenton, Ciara, Fenton, Melisa, Ferenando, Gloria, Ferguson, Cameron, Ferguson, Jenny, Ferguson, Kathryn, Ferguson, Katie, Ferguson, Susan, Ferguson, Susie, Ferguson, Victoria, Fernandes, Denzil, Fernandez, Candida, Fernandez, Eduardo, Fernandez, Maria, Fernandez Lopez, Sonia, Fernandez Roman, Jaime, Fernando, Callum J, Fernando, Jessica, Feroz, Ahmed, Ferranti, Pietro, Ferrari, Thais, Ferrelly, Eleanor, Ferrera, Alexandra, Ferriman, Emma, Ferron, Sheldon, Fethers, Nicholas, Field, Ben, Field, Janet, Field, Rebecca, Fielder, Karen, Fieldhouse, Lindsey, Fielding, Andra, Fielding, Julie, Fielding, Sarah, Fikree, Asma, Filipa, Santos, Filson, Sarah A, Finan, Shona, Finbow, Sarah, Finch, Deborah J, Finch, Joanne, Finch, Laurie, Finch, Simon, Finch, Spencer, Fineman, Natalie, Finlayson, Jim, Finlayson, Lauren, Finn, Adam, Finn, Joanne, Finnerty, Dylan, Finney, Clare, Finucane, Deborah, Fiouni, Sofia, Fiquet, Jo, Firi, Promise, Fisher, James, Fisher, Neil, Fishman, Daniel, Fishwick, Krystofer, Fitton, Carolyn, Fitzgerald, Felicity, Fitzgerald, Fiona, Fitzjohn, Karen, Flaherty, Jan, Flanagan, Michael, Flanders, Charles, Flaris, Nikolaos, Fleming, Gail, Fleming, Julie, Fleming, Lucy, Fleming, Paul, Flesher, William, Fletcher, Alison, Fletcher, Anna, Fletcher, Jonathan, Fletcher, Lucy, Fletcher, Simon, Fletcher, Sophie, Flett, Fiona, Flewitt, Karen, Flockhart, Sarah, Flood, Christopher, Floodgate, Ian, Flor, Jonathan, Florence, Vincent, Flowerdew, Mary, Floyd, Sharon, Flynn, Margaret J, Flynn, Rachel, Foden, Claire, Fofana, Adama, Fogarty, Georgina, Foley, Paul, Folkes, Linda, Fong, Tracey, Font, Daniela M, Foo, Aiwyne, Foo, Jane, Foot, Andrew, Foot, Helen R, Foot, Jayne, Forbes, Jane, Ford, Amber, Ford, Jamie, Fordham, Imogen, Foreman, Jennifer, Forester, Matthew, Forkan, Mohammad, Fornolles, Caroline, Forrest, Adam, Forsey, Ellie, Forsey, Miranda, Forshall, Thomas, Forster, Elliot, Forsyth, Abigail, Forton, Julian, Foster, Conrad, Foster, Emily, Foster, Joseph, Foster, Rachel A, Foster, Tracy, Foulds, Angela, Foulds, Ian, Fowe, Folakemi, Fowkes, Natasha, Fowler, Emily, Fowler, Robert, Fowler, Stephen, Fox, Amy, Fox, Claire, Fox, Heather, Fox, Jonathan, Fox, Laura, Fox, Lauren, Fox, Natalie, Fox, Olivia, Fox, Simon, Foxton, Sarah-Jane, Fraile, Eva, Frake, Rebecca, Francioni, Alex, Francis, Olesya, Francis, Rebecca, Francis, Sarah, Francis-Bacon, Theodora, Frankland, Helen, Franklin, Jessica, Franklin, Siobhan, Fraser, Catherine, Fratila, Andi, Frayling, Sharon, Fredlund, Martyn, Freeman, Anna, Freeman, Carol, Freeman, Elaine, Freeman, Hannah, Freeman, Nicola, Freer, Clare, French, Eleanor, French, Thomas, Freshwater, Karen, Frise, Matthew, Fromson, Renate, Frosh, Adam, Frost, John, Frost, Victoria, Froud, Oliver, Frowd, Rachel, Fryatt, Arun, Frygier, Andrzej, Fuller, Bridget, Fuller, Liz, Fuller, Lucy, Fuller, Tracy, Fullerton, Duncan, Fung, Carrie, Fung, Gayle, Funnell, Sarah, Furness, John, Fyfe, Andrew, G, Nytianandan, Gabbitas, Elizabeth, Gabriel, Claire, Gabriel, Zoë, Gachi, Hadiza, Gaffarena, Sophie, Gage, Sarah, Gahir, Joshua, Gajebasia, Sarveen, Gajewska-Knapik, Katarzyna, Galani, Zacharoula, Gale, Christopher, Gale, Hugo, Gale, Linda, Gale, Rebecca, Gali, Swetha, Gallagher, Bernadette, Gallagher, Jude, Gallagher, Rosie, Gallagher, William, Gallam, Feroze, Galliford, Joanne, Galloway, Catherine, Galloway, Chris, Galloway, Emma, Galloway, Jacqui, Galloway, James, Galvin, Anna, Galvis, Victoria, Gamble, Gareth, Gamble, Laura, Gamble, Liz, Gammon, Brian, Gan, Chien Nee, Ganaie, Muhammad B, Ganapathi, Jaikumar, Ganapathy, Ramesh, Gandhi, Kaminiben, Gandhi, Sarah, Ganesh, Usha, Ganeshanathan, Thenugan, Ganguly, Saibal, Gani, Abrar, Ganley, Pauline, Garcia, Ukraina, Garden, Emma-James, Gardener, Antoni D, Gardiner, Emma, Gardiner, Michael, Gardiner, Phil, Gardiner, Siobhan, Gardiner-Hill, Caroline, Gardner, Jonathan, Gardner, Louis, Garfield, Mark, Garg, Atul, Garg, Isha, Garlick, Nathan, Garner, Daniel, Garner, Justin, Garner, Lucie, Garner, Zoe, Garr, Rosaline, Garrero, Kathryn A, Garty, Florence, Gascoyne, Rachel, Gashau, Hyeriju, Gatenby, Aoife, Gaughan, Erin, Gaurav, Alok, Gavrila, Mariana, Gaylard, Jane, Gayle, Sophie, Geddie, Catherine, Gedge, Ian, Gee, Sarah, Geele, Fartuun, Geerthan, Kalaichelvi, Gellamucho, Minnie, Gelly, Karzan, Gelmon, Leila, Gelves-Zapata, Sandra, Genato, Gemma, Gent, Neal, Gent, Susan, Geoghegan, Natalie, George, Aparna, George, Bini, George, Sam, George, Susan, George, Tina, George, Valerie P, Georges, Simon, Georgiou, Domonique, Gerard, Peter, Gerdes, Leigh, Germain, Louise, Gerrish, Helen, Getachew, Abel, Gethin, Louise, Gettings, Siobhan, Ghanayem, Hisham, Ghavami Kia, Bijan, Ghazal, Shaista, Gherman, Anca, Ghosh, Alison, Ghosh, Dipansu, Ghosh, Justin, Ghosh, Sudhamay, Giannopoulou, Sarra, Gibani, Malick, Gibb, Chris, Gibbison, Ben, Gibbons, Kerry, Gibson, Alex, Gibson, Bethan, Gibson, Jamie, Gibson, Kimberley, Gibson, Kirsty, Gibson, Sian, Gigi, Mary, Gilbert, Cat, Gilbert, Jeanette, Gilbert, Kayleigh, Giles, Benjamin, Gilham, James, Gill, Mandy, Gill, Lynne, Gillen, Paul, Gillesen, Annelies, Gillespie, Katherine, Gillham, Elizabeth, Gillian, Andrew, Gilliland, Deborah, Gillott, Robert, Gilmour, Danielle, Gilmour, Kate, Gilmour, Lesley, Ginn, Louis, Ginting, Franciscus, Giokanini-Royal, Theodora, Gipson, Anna, Giri, Barbie, Girling, Joanna, Gisby, Rhian, Gkioni, Angelena, Gkoritsa, Aikaterini, Gkrania-Klotsas, Effrossyni, Gladwell, Amy, Glanville, James, Glasgow, Jessica, Glasgow, Susannah, Glass, Jon, Glass, Lynn, Glaysher, Sharon, Gledhill, Lisa, Glenday, Eleanor, Glennon, Ana, Glossop, Jodie, Glover, John, Glover, Kyle, Glover, Michelle, Glover Bengtsson, Jan, Glowski, Deborah, Glynn, Sharon, Gnanalingam, Chevanthy, Goddard, Julie, Goddard, Wendy, Godden, Emily, Godden, Jo, Godlee, Sarah, Godson, Emma, Godwin, Gillian, Gogoi, Sukanya, Goh, Aiky, Gohel, Manjinder, Goiriz, Rebeca, Gokaraju, Sriya, Goldacre, Raphael, Goldsmith, Arthur, Goldsmith, Portia, Gomersall, Darren, Gomez, Lucia, Gomez-Marcos, Raquel, Gondal, Ali, Gonzalez, Celia, Goodall, Jack, Goodall, Vicky, Goodenough, Bob, Goodfellow, Anna, Goodfellow, Laura, Goodlife, James, Goodwin, Camelia, Goodwin, Elizabeth, Goodwin, Jayne, Goodyear, Paula, Gooentilleke, Rajiv, Goonasekara, Michelle, Gooseman, Sheila, Gopal, Shameer, Gordon, Chris, Gordon, Sally, Gore, Robin, Gorick, Hugh, Gorman, Caitlin, Gorman, Claire, Gormely, Stuart, Gorniok, Maria, Gorog, Diana, Gorst, Michelle, Gorsuch, Thomas, Gosai, Jayshreebahen, Gosling, Rebecca, Gosling, Sally, Gosney, Georgina, Goss, Vanessa, Gotham, Dzintars, Gott, Naomi, Goudie, Elizabeth, Gould, Nicole, Gould, Susan, Goumalatsou, Charlotte, Gourbault, Lysander, Govind, Abha, Govindan, Rajesh, Gowans, Sharon, Gowda, Girish, Gowda, Rohit, Gower, Hannah, Goyal, Pankaj, Goyal, Sunil, Goyal, Sushant, Graham, Cheryl, Graham, Clive, Graham, Jonathan, Graham, Justin, Graham, Libby, Graham, Rachel, Graham, Sharon, Graham-Brown, Matthew, Grahamslaw, Julia, Grana, Gianluca, Grandison, Tracyanne, Grandjean, Louis, Grant, Alison, Grant, Ann, Grant, David, Grant, Kirstie, Grant, Matthew, Grant, Pauleen, Gravell, Rhys, Graves, Jenny, Gray, Alasdair, Gray, Catherine, Gray, Georgina, Gray, Glaxy, Gray, Jackie, Gray, Karen, Gray, Nicola, Gray, Roxanne, Gray, Sebastian, Grayson, Alan, Greaves, Fiona, Greaves, Paul, Green, Alastair, Green, Amy, Green, Amy S, Green, Charlotte, Green, Christopher A, Green, David, Green, Frederick, Green, Joel, Green, Marie, Green, Nicola, Green, Stacey, Greene, Diarra, Greenfield, Philippa, Greenhalgh, Alan, Greenwood, Daniel, Greer, Sandra, Gregory, James, Gregory, Jane, Gregory, Katie, Gregory, Tamsin, Greig, Jill, Greig, Julia, Grenfell, Rebecca, Grenier, Teena, Grenville, Jack, Gresty, Jo, Grevatt, Susan, Grey, Glaxy, Gribben, Samuel, Gribbin, Andrew, Gribble, Amy, Grieg, Natasha, Grieve, Douglas, Griffin, Ben, Griffin, Denise, Griffin, Mel, Griffith, Sian, Griffiths, Andrew, Griffiths, Daniel, Griffiths, David, Griffiths, Donna, Griffiths, Isabel, Griffiths, Mark, Griffiths, Nicola, Griffiths, Oliver, Griffiths, Sandra, Griffiths, Sarah, Griffiths, Scott, Griffiths, Yvonne, Grigoriadou, Sofia, Grigsby, Steph, Grist, Paul, Grobovaite, Evelina, Grogono, Dorothy, Grondin, Clarissa, Groome, Rachel, Grose, Pauline, Grosu, Liliana, Grounds, Jenny, Grout, Margaret, Grover, Helen, Groves, Jayne, Grubb, Neil, Grundy, Julie, Guarino, Francesca, Gudur, Sharada, Guerin, Jacinta, Guettari, Sharazeq, Gulati, Shivang, Gulia, Vikas, Gunasekara, Harsha, Gunasekera, Pumali, Gunawardena, Malin, Gunganah, Kirun, Gunn, Jessica, Gunter, Emma, Gupta, Alok, Gupta, Anup k, Gupta, Atul, Gupta, Rajeev, Gupta, Richa, Gupta, Rishi, Gupta, Tarun, Gupta, Vineet, Gupta-Wright, Ankur, Guratsky, Victoria, Gureviciute, Alvyda, Gurram, Sambasivarao, Gurung, Anju, Gurung, Bhawana, Gurung, Lilly, Gurung, Shraddha, Gurung Rai, Sabi, Guth, Hazel, Guthrine, Nick, Gyanwali, Pradip, Gyawali, Sushma, Habibi, Ruth, Hack, Berkin, Hackett, James, Hackney, Pamela, Hacon, Christian, Haddad, Aiman, Hadfield, Denise, Hadfield, Nicholas, Hadfield, Sally, Hadjiandreou, Michalis, Hadjisavvas, Nikolaos, Haestier, Anna, Hafiz, Nauman, Hafiz-Ur-Rehman, Rana, Hafsa, Javed, Hagan, Samantha, Hague, Jack William, Hague, Rosemary, Haider, Nafeesah, Haigh, Kate, Haile, Victoria, Hailstone, Jessica, Haines, Christina, Hainey, Scott, Hair, Morton, Hairsine, Brigid, Hajnik, Juraj, Hake, Danielle, Hakeem, Lukman, Haldeos, Anne, Halder, Writaja, Hale, Emily, Hale, Jennie, Halevy, Carmel, Halford, Paul, Halford, William, Halim, Alaina, Hall, Alistair, Hall, Anthony, Hall, Claire, Hall, Elizabeth, Hall, Fiona, Hall, Helen, Hall, Jennifer, Hall, Kathryn, Hall, Laura, Hallas, Jan, Hallas, Kyle, Hallett, Charles, Halliday, Jackie, Hallman, Akmal, Halls, Heather, Hamdollah-Zadeh, Maryam, Hamed-Adekale, ifedadepo A, Hameed, Bilal, Hameed, Mohammed, Hamers, Raph, Hamid, Imran, Hamie, Mohamad, Hamill, Raymond, Hamilton, Bethany, Hamilton, Fergus, Hamilton, Gus, Hamilton, Leigh, Hamilton, Melanie, Hamilton, Nicola, Hamilton, Sara, Hamlin, Ruth, Hamlyn, Eleanor, Hammans, Beatrice, Hammersley, Shirley, Hammerton, Kate, Hammond, Bev, Hammond, Emily, Hammond, Leah, Hammond, Sally, Hammonds, Fiona, Hamoodi, Ibrahim, Hampshire, Karen, Hampson, James A, Hampson, Jude, Hampson, Lucy, Hamzah, Lisa, Han, Jenny, Hanci, Ozan, Hand, Sadiyah, Handayani, Lala, Handford, Jasmine, Handrean, Soran, Handzewniak, Nina K, Haney, Sarah, Hanif, Sheharyar, Hanison, E, Hanison, Esther, Hannah, Jennifer, Hannington, Amy, Hannun, Merhej, Hanrath, Aidan, Hanratty, Helena, Hansen, Daniel, Hanson, Anita, Hanson, Ashley, Hanson, Helen, Hanson, Jane, Hanson, Kathryn, Hanson, Steve, Haq, Mazhar Ul, Haqiqi, Ala, Haque, Monjurul, Harcourt, Henry, Harden, Lesley, Harding, Zoe, Hardman, Simon, Hardwick, Marc, Hardy, Gareth, Hardy, Joanna, Haresh, Kumar, Harford, Rachel, Hargadon, Beverley, Hargraves, James, Hargreaves, Carolyn, Harin, Alice, Haris, Mohammed, Harlock, Edward, Harman, Paula, Harman, Tracy, Harmer, Mark, Haroon, Muhammad A, Harper, Charlie, Harper, Heather, Harper, James, Harper, Peter, Harper, Rosemary, Harrhy, Sarah, Harrington, Kate, Harrington, Sian, Harrington-Davies, Yasmin, Harris, Jade, Harris, Jess, Harris, John, Harris, Laura, Harris, Marie-Clare, Harris, Nichola, Harris, Sophie, Harrison, David, Harrison, Laura, Harrison, Melanie, Harrison, Olakunbi A, Harrison, Rachael, Harrison, Rowan, Harrison, Susie, Harrison, Thomas, Harrison, Wendy, Harrod, Elizabeth, Hart, Ciaran, Hart, Dominic, Hartley, Jessica, Hartley, Lisa, Hartley, Rosemary, Hartley, Ruth, Hartley, Tom, Hartrey, William, Hartridge, Phillipa, Hartshorn, Stuart, Harvey, Alice, Harvey, Angela, Harvey, Anna, Harvey, Max, Harwood, Catherine, Harwood, Helen, Harzeli, Zoe, Haselden, Brigitte, Hashem, K, Hashimm, Mohammed, Hashimoto, Tadaaki, Hashmi, Imranullah, Haslam, Jack, Haslam, Zena, Hasnip, Grace, Hassan, Adil, Hassan, Ali, Hassan, Amro, Hassan, Awab, Hassan, Zeinab, Hassasing, Sapna, Hassell, Jane, Hassell, Philip, Hastings, Alex, Hastings, Bethany, Hastings, Janice, Hathaway-Lees, Sarah, Hatton, Jonathan, Hau, Jennifer, Havinden-Williams, May, Havlik, Stefan, Hawcutt, Daniel B, Hawes, Kadean, Hawes, Liz, Hawes, Nicola, Hawker, Lydia, Hawkins, Annie, Hawkins, Joe, Hawkins, Nancy, Hawkins, W John, Hawley, Dan, Hawley-Jones, Ed, Haworth, Edward, Hay, Alasdair W, Hay, Cathy, Hayat, Amna, Hayat, Jamal, Hayathu, Mohamed-Riyal, Hayes, Anne, Hayes, Jonas, Hayes, Kate, Hayes, Melony, Hayes, Fiona, Hayle, Patrick, Haylett, Chloe, Hayman, Antara, Hayman, Melanie, Haynes, Matthew, Haynes, Richard, Hayre, Rachel, Hays, Carole, Haysom, Sarah, Hayward, James, Haywood, Patrick, Hazelton, Tracy, Hazenberg, Phoebe, He, Zhengmai, Headon, Elizabeth, Heal, Carrie, Healy, Brendan, Healy, Jessica L, Hearn, Amy, Heasman, David, Heath, Angela, Heath, Debbie, Heath, Rowan, Heaton, Diane, Heavens, Adam, Hebbron, Kerry, Heckman, Catherine, Hector, Gemma, Heddon, Sadie, Hedges, Andy, Hedges, Katrine, Heeley, Cheryl, Heeney, Elaine, Heinink, Richard, Heire, Rajdeep, Helgesen, Ingvild, Hemingway, Joanne, Hemmila, Ulla, Hemmings, Beth, Hemphill, Scott, Hemsley, Deborah, Henderson, Abigail, Henderson, Eilidh, Henderson, Jennifer, Henderson, Steven, Henry, Joanne, Henry, Karol, Henry, Lavinia, Henry, Margo, Henry, Natalie, Henshall, David, Herdman, Gillian, Herdman-Grant, Rosaleen, Herkes, Morag, Hernandez, Fe Marie, Heron, Emma, Heron, Lisa, Herrington, William, Heselden, Emilia, Heslop, Peta, Heslop, Tracey, Hester, Simon, Hetherington, Emily, Hetherington, Joseph, Hettiarachchi, Chamila, Hettiarachchi, Pramodh, Hewer, Hayley, Hewertson, John, Hewetson, Anna, Hewins, Sue, Hewitson, Nicola, Hewitt, Claire, Hewitt, Davina, Hewitt, Richard, Hey, Samuel, Heyderman, Robert S, Heydtmann, Mathis, Heys, Joseph, Heywood, Jonathan, Hibbert, Meg, Hickey, John, Hickey, Naomi, Hickey, Peter, Hicks, Alex, Hicks, Jenny, Hicks, Scott R, Higbee, Daniel, Higgins, Lucy, Higham, Andrew, Highcock, Martin, Highgate, Judith, Hikmat, Mondy, Hill, Amanda, Hill, Helen, Hill, Joanne, Hill, Lisa, Hill, Lucy, Hill, Phoebe, Hill, Uta, Hilldrith, Annette, Hillman-Cooper, Catherine, Hilton, Jon, Hilton, Zoe, Hinch, Sarah, Hindle, Andrew, Hindley, Esther, Hindmarsh, Alice, Hine, Paul, Hinshaw, Kim, Hird, Clare, Hirst, Claire, Hirst, Lindsay, Hives, Jemma, Hlaing, Htet Myat, Ho, Benson, Ho, David K K, Ho, Rosemary, Hoare, Michaela, Hobden, David, Hobden, Gill, Hobrok, Maria, Hobson, Simon, Hodge, Christopher, Hodge, Simon, Hodgen, Lesley, Hodgetts, George, Hodgkins, Holly, Hodgkinson, Sally, Hodgson, David, Hodgson, Helen, Hodgson, Luke, Hodgson, Sheila, Hodkinson, Gemma, Hodson, Kenneth, Hodson, Mike, Hogan, Alison, Hogben, Matthew, Hogg, Lucy, Hoggett, Lee, Holborow, Abigail, Holbrook, Catherine, Holbrook, Rebecca, Holden, Catherine, Holden, Jill, Holden, Melinda, Holden, Sophie, Holder, Thomas, Holdhof, Niels, Holdsworth, Hannah, Holland, Lisa, Holland, Maureen, Holland, Nicky, Holland, Poppy, Holland, Susan, Hollands, Marie L, Holliday, Elizabeth, Holliday, Kyra, Holliday, Mark, Holling, Nina, Hollos, Laszlo, Hollos, Nora, Holloway, Leah, Holloway, Simon, Hollowday, Max, Hollyer, Marcus, Holman, Amy, Holmes, Ann, Holmes, Megan, Holmes, Raphael, Holmes, Rebecca, Holroyd, Kelly, Holroyd-Hind, Beth, Holt, Lyndsey, Holt, Siobhan, Holt, Susie, Holyome, Alexandra, Home, Marie, Homewood, Renate, Hong, Kate, Hoole, Louise, Hooper, Clare, Hope, Samantha, Hope, Susan, Hopkins, Bridget, Horby, Peter W, Horler, Stephanie, Hormis, Anil, Hornan, Daniel, Hornby, Nicola, Horne, Thomas, Horne, Zoey, Horner, Rebecca, Horrobin, Caroline, Horsford, Latoya, Horsford, Megan, Horsford, Mark, Horsham, Valana, Horsley, Alexander, Horsley, Ashley, Horsley, Elizabeth, Horton, Sarah, Hosea, Jane, Hoskins, Toby, Hossain, Muhammad S, Hossain, Rashed, Hough, Maxine, Hough, Sarah, Houghton, Catherine, Houghton, Kathryn, Houlihan, Rebecca, Housely, Kay, Houston, Hamish, Hovvels, Roseanna, How, Lee, Howaniec, Laura, Howard, Joanne, Howard, Kate, Howard, Laura, Howard, Linda, Howard, Lucy, Howard, Megan, Howard, Sarah, Howard, Stuart, Howard-Griffin, Richard, Howard-Sandy, Louise, Howe, Serena, Howell, Alice, Howells, Mark, Howie, Lyn, Howlett, Kerry, Howlett, Sophie, Howman, Ruth, Hrycaiczuk, Josh, Htet, Hein, Htoon, Naing Z, Htwe, Su, Hu, Ying, Huah, Chiang O H, Huang, Sylvia, Hubbard, Kelly, Huckle, Abby, Huda, Shahzya, Hudak, Alison, Hudig, Lisa, Hudson, Heather, Hudson, Suzanne, Hudson, Oli, Hufton, Alison, Huggins, Connor, Hughes, Alistair, Hughes, Caitlin, Hughes, Emma, Hughes, Gareth, Hughes, Heather, Hughes, Luke, Hughes, Martin, Hughes, Rachel, Hughes, Rebecca, Hughes, Samantha, Hughes, Stephen, Hughes, Vikki, Hughes, Wesley, Huhn, Lukas, Hui, Ching, Hulbert, Ruth, Hull, Diana, Hull, Grace, Hull, Robert, Hulme, Amanda, Hulme, Peter, Hulse, Wendy, Hulston, George, Hum, Ryan, Hume, Megan, Humphrey, Charlotte, Humphries, Alasdair, Humphries, Amy, Humphries, Joanne, Hunt, Charlotte, Hunt, Fiona, Hunt, Jane, Hunt, Jonquil, Hunt, Kristen, Hunt, Luke, Hunt, Molly, Hunt, Sophie, Hunter, Alexandra, Hunter, Catherine, Hunter, Ewan, Hunter, Karl, Hunter, Neil, Hunter, Ross, Hunter, Sophie, Huntington, George, Huq, Fuad, Hurditch, Elizabeth, Hurdman, Judith, Hurley, Cian, Hurley, Katrina, Husain, Mohammed A, Husaini, Syeda Y, Huson, Coralie, Hussain, Afreen, Hussain, Chreif, Hussain, Ibraar, Hussain, Ifza, Hussain, Mohammad, Hussain, Mohammed, Hussain, Muhammad, Hussain, Reda, Hussain, Rizwana, Hussain, Samia, Hussain, Sanniah, Hussain, Yasmin, Hussam El-Din, Mohammed, Hussein, Samahir F E M, Hussein, Ziad, Hussey, Rebecca, Hussien, Adiel H, Hutchinson, Anja, Hutchinson, Camille, Hutchinson, Dorothy, Hutchinson, Elizabeth, Hutchinson, John, Hutsby, Claire, Hutton, Paula, Huyen, Thuong, Huynh, Hieu, Hydes, Daniella, Hyde-Wyatt, Jamie, Hynes, Niamh, Hyslop, Megan, Iakovou, Angeliki, Ibison, Katherine, Ibraheim, Mazen, Ibrahim, Abdalla, Ibrahim, Ahmed, Ibrahim, Asil, Ibrahim, Javed, Ibrahim, Mamoun, Ibrahim, Mohamed, Ibrahim, Wadah, Icke, Becky, Idowu, Adetokunbo I, Idrees, Muhammad, Idrees, Nauman, Iftikhar, Hina, Iftikhar, Mawara, Igwe, Chukwuemeka, Igwe, Ogechukwu, Ijaz, Mohammad, Ikomi, Amaju, Iles, Clare, Iliodromiti, Stamatina, Ilsley, Mary, Ilves, Lorna, Ilyas, Fatima M, Imam-Gutierrez, La'ali, Iman, Mohamed, Imray, Christopher, Imtiaz, Haider, Ingham, Jack, Ingham, Jo, Ingham, Julie, Ingham, Rory, Ingle, Tejas, Inglis, Jennifer, Inglis-Hawkes, Samantha, Ingram, Anne, Ingram, Luke, Ingram, Tanya, Innes, Nicholas, Inns, Peter, Inpadhas, Vithusha, Inweregbu, Ken, Ionescu, Andreea A, Ionita, Ana, Iordanov, Ilian P, Ipe, Anil, Iqbal, Javaid, Iqbal, Madiha, Iqbal, Mishal, Iqbal, Mohammed, Iqbal Sait, Faisal, Irabor, Iziegbe, Ireland, Jane, Irisari, Jamie, Irons, Robert, Irshad, Mohannad, Irshad, Muhammad S, Irvine, Janice, Irvine, Val, Irving, Robert, Ishak, Mina, Isherwood, Erica, Isitt, George, Islam, Aminul, Islam, Tariqul, Islam, Samsul, Islim, Abdurrahman, Ismail, Ali, Ismail, Omar, Ison, Caroline, Israa, M'hamedi, Isralls, Sharon, Istiqomah, Herny, Ivan, Monica, Ivenso, Chineze, Ivin, Nicholas, Ivy, Ashleigh, Iwanikiw, Sophie, Ixer, Karen, Iyer, Menaka, Iyer, Mia, Jabbar, Kashif, Jack, Calum, Jackman, Joanne, Jackman, Sophie, Jackson, Amanda, Jackson, Ben, Jackson, Beth, Jackson, Ella, Jackson, Helen, Jackson, Lauren, Jackson, Melanie, Jackson, Nicola, Jackson, Shane, Jackson, Yvonne, Jacob, John, Jacob, Patricia, Jacob, Reni, Jacques, Nicola, Jafar, Anisa, Jafferji, Daniel, Jaffery, Ali, Jagadish, Chandrashekar, Jagannathan, Vijay, Jagpal, Mandeep, Jain, Neemisha, Jain, Seema, Jain, Susan, Jain, Swati, Jaiswal, Sanjay, Jajbhay, Danyal, Jaki, Thomas, Jallow, Bintou, Jaly, Yusuf, Jama, Rose, Jamal, Ashraf, Jamal, Sabine, Jamal, Zeba, Jameel, Yasmin, James, Albie, James, Christie, James, Claire, James, Kate, James, Lee, James, Linda, James, Lorraine, James, Mark, James, Monica, James, Nicholas, James, Olivia, James, Patricia, James, Rebecca, James, Ruth, James, Sharon, James, Somerset, James, Tracy, Jameson, Jack, Jamieson, Louise, Jamison, Aaron, Jane, Phoebe, Janes, Karen, Janmohamed, Azara, Japp, Deepa, Jaques, Peter, Jardim, Victor, Jardine, Catherine, Jarman, Claire, Jarnell, Emma, Jarvie, Ellie, Jarvis, Claire, Jarvis, Rosina, Jastrzebska, Patrycja, Javed, Hafsa, Javier, Aristotle, Jawad, Mays, Jawaheer, Lona, Jayachandran, Anu, Jayachandran, D, Jayadev, Anita, Jayakumar, Angelina, Jayaram, Deepak, Jayaram, Ravi, Jayasekera, Geeshath, Jayatilleke, Thilina, Jayebalan, Abi, Jeater, Jane, Jeddi, Saman, Jeebun, Vandana, Jeelani, Mohammad S, Jeffery, Katie, Jeffrey, Helen, Jeffrey, Rachel, Jeffreys, Nathan, Jeffs, Benjamin, Jeffs, Carol, Jeganathan Ponraj, Jegan P, Jegede, Debbie, Jemima, Taylor, Jenkin, Ifan, Jenkins, Alison, Jenkins, Christopher, Jenkins, David, Jenkins, Elinor, Jenkins, Ian, Jenkins, Paula, Jenkins, Sarah, Jenkins, Sian, Jenkins, Stephen, Jennings, Felicia, Jennings, Jacqui, Jennings, Louise, Jennings, Virginia, Jerome, Ellen, Jerry, Douglas, Jervis, Greame, Jessup-Dunton, Ellen, Jesus Silva, Jorge A, Jetha, Champa, Jethwa, Kishan, Jha, Roshan K, Jhanji, Shaman, Jian, Khoo, Jiao, Zhixin, Jimenez, Laura, Jimenez Gil, Ana, Jith, Jithin, Joefield, Teishel, Johal, Navraj, Johal, Simran, Johannessen, Karine, Johari, Aisyah, John, Annie, John, Anu, John, Maya, John, Navin, Johns, Emma, Johns, Margaret, Johnson, Antoinette, Johnson, Emma, Johnson, Gillian, Johnson, Kathryn, Johnson, Katie, Johnson, Luke, Johnson, Mark, Johnson, Nelsonseelan, Johnson, Oliver, Johnson, Rachel, Johnston, Brogan, Johnston, Claire, Johnston, Janet, Johnston, Susan, Johnston, Victoria, Johnstone, Dawn, Johnstone, Ed, Johnstone, Janet, Joishy, Manohar, Jones, Adam, Jones, Alistair, Jones, Amy, Jones, Angela, Jones, Annabel, Jones, Ben, Jones, Bryony, Jones, Carys, Jones, Ceri, Jones, Charlotte, Jones, Christine E, Jones, Debra, Jones, Emily, Jones, Gareth, Jones, Geraldine, Jones, Jac, Jones, James, Jones, Jonathon, Jones, Julie, Jones, Kate E, Jones, Kimberly, Jones, Laura, Jones, Laura M, Jones, Louise, Jones, Mathew, Jones, Nancy, Jones, Nicola, Jones, Olivia, Jones, Paul, Jones, Philip H, Jones, Rhianna, Jones, Ruth E, Jones, Samantha, Jones, Sophie, Jones, Stefanie, Jones, Steve, Jones, Susan, Jones, Taya, Jones, Thomas, Jones, Tim, Jones, Tracey, Jonnalagadda, Ramya, Jordache, Rebecca, Jordan, Michele, Jordan, Sarah, Jose, Abi, Jose, Litty, Jose, Louise, Jose, Sanal, Joseph, Anna, Joseph, Gigee, Joseph, P Aiden, Joseph, Rosane, Joseph, Sibet, Joshi, Dhaara, Joshi, Mehul, Joshi, Pratichi, Joshi, Tushar, Josiah, Benz, Joy, Lijo, Joyce, Tiffany, Ju, Hong, Ju Wen Kwek, Adriel, Judd, Andrew, Jude, Edward, Judge, Parminder, Juhl, Jessica, Jujjavarapu, Sirisha, Juniper, Mark, Juszczak, Edmund, Jyothish, Deepthi, Kabiru Dawa, Kasamu, Kacar, Mark, Kadam, Nikhil, Kader, Nicole, Kailey, Ajai, Kain, Matthew, Kakoullis, Gail, Kala Bhushan, Azad, Kalayi, Richard J K, Kaliannan Periyasami, Roobala, Kallistrou, Efthymia, Kalmus Eliasz, Thomas, Kalsoom, Seika, Kam, Elisa, Kamara, John, Kamath, Ajay, Kamath, Prakash, Kamath, Ravindra, Kamerkar, Siddharth A, Kametas, Nick, Kamfose, Musaiwale, Kamundi, Charlotte, Kanabar, Dharmesh, Kane, Leia, Kankam, Osei, Kannan, Thogulava, Kant, Abhinav, Kapil, Vikas, Kapoor, Ritoo, Kapoor, Sonal, Kaprapina, S, Kar, Sourjya, Kara, Janaka, Karbasi, Elshad, Karelia, Shivaali, Kark, Rona, Karkey, Abhilasha, Karmali, Soheilali, Karunanithi, Viji, Karunaratne, Nicholas, Kasianczuk, Natashja, Kasiappan Balasubramanian, Anbhu, Kasipandian, Vidya, Kassam, Rizwan, Kathirgamachelvam, Janarth, Katsande, Victoria, Kaul, Kulbinder, Kaur, Daljit, Kaur, Dervinder, Kaur, Jasmin, Kaur, Jaspreet, Kaur, Simran, Kausar, Zunaira, Kavanagh, Lisa, Kavanagh, susan, Kawser, Mohammad A Al, Kay, Andrea, Kay, Julie, Kay, Robert, Kay, Sarah, Kayappurathu, Jossy N, Kaye, Callum, Kazeem, Ahemd, Ke, Min, Keady, Timothy, Kearns, Rachel, Kearsley, Nichola, Keating, Joanne, Keating, John, Keating, Liza, Keddie-Gray, Elizabeth, Keegan, Breffni, Keen, Rachel, Keenan, Natalie, Kefas, Jonathan, Kegg, Stephen, Keith, Laura, Keke, Uzoamaka, Kellett, Joanne, Kelliher, Jo, Kelly, Alison, Kelly, David, Kelly, Diane, Kelly, Dominic, Kelly, Emma, Kelly, Hannah, Kelly, Laura, Kelly, Louisa, Kelly, Martin, Kelly, Michael, Kelly, Rosalind, Kelly, Sinead, Kelly, Stephanie, Kelly, Stephen, Kelly-Baxter, Mary, Kelsall, Olivia, Keltos, Marketa, Kemp, Timothy, Kendall, Emma, Kendall-Smith, Alexandra, Kennard, Sarah, Kennedy, Ann, Kennedy, James, Kennedy, Melanie, Kennedy-Hay, Sophie, Kenny, Julia, Kent, Melanie, Keogan, Lynne, Keough, Alexander, Kernaghan, Dawn, Kerr, A, Kerr, Andrew, Kerrison, Caroline, Kerry, Anthony, Kerslake, Helen, Kerslake, Ian, Kerss, Helen, Keshet-Price, Jocelyn, Kestelyn, Evelyne, Keyte, Georgina, Khadar, Abdul, Khalid, Ali, Khalid, Hadika, Khalid, Muhammad U, Khalid, Syed, Khalid, Mariha, Khalifa, Tarek, Khalil, Amir, Khalil, Asma, Khalil, Sijjad, Khan, Abubakar, Khan, Ali, Khan, Al-Imran, Khan, Arham, Khan, Asad, Khan, Aurangzeb, Khan, Burhan, Khan, Fatimah, Khan, Kausik, Khan, Malik A, Khan, Marria, Khan, Mehrunnisha, Khan, Mohammad, Khan, Myra, Khan, Nayeem, Khan, Nuzhath, Khan, Omar, Khan, Rabia, Khan, Rahila, Khan, Shabana, Khan, Shahul, Khan, Shoaib, Khan, Tasaduksultan, Khan, Waleed, Khan, Waseem, Khan, Zuhair, Khan Tharin, Mohammad S, Khatana, Usman F, Khatri, Januka, Khatri, Jibran, Khatri, Jyoti, Khatun, Hafiza, Khatun, Taslima, Kheia, Mena, Khera, Jacyntha, Khin, Htet Htet Ei, Khoja, Najaf, Khokhar, Kiran, Khoo, Joshua, Khurana, Chloe, Kibaru, Joyce, Kibutu, Faith, Kidd, Andrew, Kidd, Michelle, Kidney, Joe, Kidney, Shane, Kieffer, Will, Kilbane, James, Kilby, Caroline, Kilich, Eliz, Killen, Eileen, Kilner, Beverley, Kilroy, Susan, Kim, Bomee, Kim, Jee Whang, Kim, Minhee, Kimber, Aly, Kimber, Sarah, King, Andy, King, Barbara, King, Hayley, King, Jennifer, King, Jenny, King, Kirsten, King, Matthew, King, Rachel, King, Sarah, King, Victoria, King-Oakley, Emily, Kingsmore, Laura, Kinnear, Deborah J, Kinney, Fiona, Kiran, Sidra, Kirby, Alison, Kirk, Adam, Kirk, Jeremy, Kirk, Jill, Kirk, Jodie, Kirkby, Amy, Kirkham, Emily, Kirkman, Gemma, Kirkpatrick, Lucy, Kirwan, Ursula, Kitching, Toby, Kitto, Laura, Kittridge, Lauren, Klaczek, Sarah, Kleemann, Frieder, Kmachia, Susan, Knapp, Christopher P, Knibbs, Lucy, Knight, Alicia, Knight, Fraser, Knight, Marian, Knight, Sarah, Knight, Steven, Knight, Tom, Knights, Ellen, Knights, Jane, Knolle, Martin, Knopp, Paul, Knowles, Charlotte, Knowles, Karen, Knowles, Laurence, Knox, Emily, Knox, Lucy, Koch, Oliver, Kocsor, Marta, Kodituwakku, Ronan, Koduri, Gouri, Koe, Yuan Jun, Koirata, Aisha, Kolakaluri, Eirene, Kolodziej, Magdalena, Kolokouri, Eirini, Kon, Samantha, Konar, Niladri, Kononen, Mari, Konstantinidis, Athanasios, Kontogonis, Rachel, Koo, Hui Fen, Koopmans, Imogen, Kopyj, Emmanuela, Korcierz, Laura, Korolewicz, James, Koshy, George, Kosmidis, Chris, Kosztolanyi, Csilla, Kotecha, Jalpa, Kothandaraman, Easwari, Koukou, Katerina, Kountourgioti, Athanasia, Kouranloo, Koushan, Kousar, Rukhsana, Kousteni, Margarita, Koutalopoula, Anastasia, Kovac, Maja, Kozak Eskenazia, Alex, Krasauskas, Kestutis, Krishnamurthy, Raghu, Krishnamurthy, Vinodh, Krishnan, Manju, Krishnan, Hari, Krishnapalli, Nagaratna, Krizak, Suzanne, Krueper, Stephen, Krupej, Sean, Krzowski, James, Kubaisi, Ria, Kubisz-Pudelko, Agnieszka, Kuckreja, Shavita, Kudsk-Iversen, Soren, Kudzinskas, Aurimas, Kukadiya, Chirag, Kulkarni, Nainesha, Kumala Dewi, Susantika, Kumar, Aditi, Kumar, Ayesha, Kumar, Mayur, Kumar, Ramesh, Kumar, Ravi, Kumar, Rita, Kumar, Rupa, Kumar, Satish, Kumar, Vikas, Kumar, Vimal, Kundu, Arun, Kunst, Heinke, Kupiec, Klaudia, Kurani, Amit, Kurdy, Mohammed, Kuriakose, Kevin, Kurian, Rincy, Kurmars, Vimal, Kuronen-Stewart, Cameron, Kusangaya, Ranganai S, Kushakovsky, Vlad, Kutera, Anna, Kuverji, Apexa, Kyei-Mensah, Amma, Kyere-Diabour, Thyra, Kyi, Moe, Kyi, Nyan M, Kyle, Laura, Kyriaki, Karali-Tsilimpari, Labao, Julius, Lacey, Louise, Lack, Nikki, Lacson, Maria, Ladan, Zahra, Ladlow, Emma, Lafferty, Heather, Lagnado, Alice, Laha, Shondipon, Lahane, Sushil, Lai, Clement, Lai, James, Laidler, Paula, Laing, Robert, Laing-Faiers, Inez, Laity, Emily, Lake, Katharine, Lakeman, Nicki, Lalloo, David, Lalloo, Fiona, Lam, Alison, Lam, Classy, Lamb, Fiona, Lamb, Lucy, Lamb, Thomas, Lambert, Pauline, Lameirinhas, Claudia, Lami, Mohammed K G, Lamont, Holly, Lamparski, Michal, Lamrani, Djillali, Lanaghan, Christine, Lancona-Malcolm, Ivone, Landers, Geraldine, Landray, Martin J, Lane, Matthew, Lane, Nicholas, Lang, Alidih, Lang, Stephen, Langer, Daniel, Langley, Margaret, Langoya, Charles, Langridge, Emma, Langthorne, Emily, Langton, Helen, Lara, Beatriz, Large, Taiya, Lassa, Samuel, Last, Anna, Latham, Scott, Latham, Victoria, Latheef, Afzal, Latif, Larissa, Latt, Nang, Lau, Carmen, Lau, Dawn, Lau, Eva, Laura, Gonzalez G, Laurenson, Myra, Lavington, Eloise, Law, Hou, Law, Jessica, Law, June, Law, Kar Yee, Law, Penny, Law, Richard, Lawless, Laura, Lawrence, Chris, Lawrence, Emma, Lawrence, Geoffrey, Lawrence, Holly M, Lawrence, Neil, Lawrie, Ryan, Lawson, Louise, Lawson, Natalie, Lawson, Rod, Lay, Michael, Laybourne, Stephen, Laycock, Christine, Layug, Reina, Lazo, Maria, Le, Vietland, Lea, Amelia, Lea, William, Leach, Louisa E, Leadbitter, Ian, Leahy, Thomas, Lean, Richard, Leandro, Lorna, Leaning, Darren, Leary, Ruth, Leason, Sandra, Ledingham, Marie Anne, Lee, Caroline, Lee, Emma, Lee, Hannah, Lee, Irish, Lee, Joshua, Lee, Judith, Lee, Sam, Lee, Shannon, Lee, Shi Han, Lee, Simon, Lee, Sindy, Lee, Stephanie, Lee, Tracey, Lee, Xiang, Lee, Robyn, Lees, Diana, Lees, Jennifer, Legge, Helen, Leggett, Julian, Leigh-Ellis, Katie, Leitch, David, Leitch, Nicky, Lekoudis, Eleni, Lemessy, Petula, Lemoine, Nicholas, Lenagh, Rebecca, Leng, Katy, Lennon, Katrina, Lennon, Liz, Leonard, Beth, Leonard, Kelly, Leong, Wen, Leopold, Nicky, Lepiarczyk, Oskar, Leslie, Isla, Lester, Eleni, Levell, Emma, Levett, Chris, Levynska, Anastasia, Lewin, Alice, Lewis, Alison, Lewis, Christopher, Lewis, David, Lewis, Dee, Lewis, Heather, Lewis, Joanne, Lewis, Joseph, Lewis, Kathryn, Lewis, Keir, Lewis, Leon, Lewis, Mandy, Lewis, Marissa, Lewis, Nicolas, Lewis, Robert, Lewis-Clarke, Catherine, Lewszuk, Adam, Lewthwaite, Penny, Ley, Samantha, Liao, Angela, Licence, Victoria, Lieberman, David, Liebeschuetz, Susan, Light, Teresa, Lightfoot, Nicky, Lillie, Patrick, Lillis, Ashling, Lim, Ben, Lim, Carys, Lim, Ee Thong, Lim, Ivy, Lim, Terence, Lim, Wei Shen, Lim, Wilson, Limb, James, Limbu, Dipraj, Limbu, Usha, Linares, Christian, Linden, Dermot, Lindergard, Gabriella, Lindley, Kate, Lindsay, Charlotte, Lindsay, Emily, Lindsay, Max, Lindsay- Clarke, Helen, Ling, Mirella, Lingam, Claire, Linkson, Linette, Linn, Thinzar, Linney, Mike, Lippold, Conrad, Lipscomb, George, Lipscomb, Karen, Lipskis, Laura, Lisboa, Ana, Lister, Evangeline, Little, Jeff, Little, Sam, Littlejohn, Lucy, Liu, Sky, Liu, Xuedi, Llanera, Daniel K, Llewellyn, Rhiannon, Llewelyn, Martin, Lloyd, Adam, Lloyd, Aimee, Lloyd, Arwel, Lloyd, Oliver, Lloyd, Richard, Lo, Su, Loader, David, Loan, Caroline, Lobosco, Livia, Lock, Lydianne, Lock, Sara, Lock, Stephen, Locke, Angela, Locke, Jacqueline, Locke, Thomas, Locke, Jacqueline, Lockett, Teresa, Lodge, Jeorghino, Lodhia, Krishan, Lofthouse, Martina, Loftus, Heather, Logan, Meg, Logue, Chloe Alice, Loh, Sook Yin, Lokanathan, Siddharth, Lomme, Kaatje, London, Emily, Long, Gabriella, Long, Natalie, Longbottom, Katherine, Longhurst, Bev, Longshaw, Mark, Longstaffe, Sarah, Lonnen, Jennifer, Lonsdale, Caroline, Looby, Laura, Loosley, Ronda, Lopes, Liliana, Lopez, Paola, Lopez, Paula, Lord, Robert W, Lord, Stephen, Lorimer, Claire, Loro, Francesco, Lorusso, Rachel, Loughlin, Catherine, Lovegrove, Wayne, Loveless, Robert, Lovell, Maxine, Loverdou, Angeliki, Low, Andrew, Low, Jen Mae, Low, Shona, Lowe, Alastair, Lowe, Catherine, Lowe, Emily, Lowe, Faye, Lowe, Leanne, Lowe, Michael, Lowsby, Richard, Lowthorpe, Vicki, Lubimbi, Gamu, Lubina Solomon, Alexandra, Lucas, Georgia, Lucas, Jacob, Lucey, Alice, Lucey, Olivia, Luck, Suzanne, Lui, Lok Hin, Luintel, Akish, Luke, H, Luke, Jane, Lungu, Naomi, Lunia, Apurva, Lunn, Muriel, Luo, Ji, Luscombe, Mark, Luveta, Jocelyn, Luximon, Cindy N, Lwin, Khine, Lwin, Myat, Lye, Alison, Lyell, Barrie, Lyka, Elisavet, Lynas, Audrey, Lynch, Ceri, Lynch, Daniel, Lynch, Daniella, Lynch, Stephen, Maamari, Rea-Grace, Mabb, Hannah, Mabelin, Louies, Mabeza, George, Macaro, Jessica, Macconaill, Kateryna, Macdonald, Chloe, Macduff, Andrew, Macfadyen, Claire, Macfarlane, James G, Macfarlane, Jill, Macfarlane, Laura, Macharia, Irene, MacInnes, Lisa, MacIntyre, Iain, MacIntyre, Jill, Mack, Kirsten, Mackay, Callum, Mackay, Euan, Mackay, Laura, Mackenzie, Alexander, Mackenzie, Matt, MacKenzie Ross, Robert, Mackey, Ami, Mackie, Fiona, Mackie, Jennifer, Mackie, Robert, Mackinlay, Carolyn, Mackintosh, Claire, Mackintosh, Katherine, MacLeod, Mary J, Macleod, Shona, Macmahon, Michael, MacNair, Andrew, Macphee, Catherine, Macpherson, Iain, Macrae, Catriona, MacRaild, Allan, Madden, Alannah, Madden, Mary, Madden-McKee, Christopher, Maddison, Sally, Madeja, Norman, Madhivathanan, Pradeep, Madhusudhana, Madhavi, Madu, Alpha, Madziva, Lorraine, Mafham, Marion, Magee, Nick, Magezi, Frederick, Maghsoodi, Negar, Magier, Christopher, Magnaye, Lessica M, Magriplis, Marios, Magtalas, Michelle, Mahabir, Natasha, Mahadevan-Bava, Subramanian, Maharajh, Amitaa, Maharajh, Anjanie, Maharjan, Kijan, Mahaveer, Ajit, Mahay, Bal, Mahay, Kanta, Mahdi, Amy, Mahdi, Hibo, Mahdi, Noor, Mahendiran, Thushika, Mahendran, Siva, Maher, Sarah, Maheswaran, Anistta, Maheswaran, Shameera, Maheswaran, Tina, Mahjoob-Afag, Parisa, Mahmood, Ahmed, Mahmood, Farhana, Mahmood, Hussain, Mahmood, Waheed, Mahmood, Zahra, Mahmoud, Hager, Mahmud, Mohammed, Mahony, Ewan, Mahungu, Tabitha, Mair, Luke, Majekdunmi, Toluwani, Majid, Kesson, Major, Amy, Major, Rupert, Majumdar, Jaydip, Majumder, Mohammad K H, Mak, Tsz L A, Makan, Annabel, Makanju, Esther, Makin, Stephen, Makinde, Wura-Ola, Makkeyah, Yahya, Malanca, Marius, Malcolm, Hannah, Malein, Flora, Malhan, Neeraj, Malicka, Agnieszka, Malik, Ayesha, Malik, Gulshan, Maljk, Mohammed, Mallett, Paul, Mallinder, Petrina, Mallison, Georgia, Mallon, Louise, Malone, Edward, Maloney, Gracie, Mamman, Madhu, Man, Irene, Man, Kathy, Mancinelli, Rossana, Mancuso-Marcello, Marco, Mandal, Shrawan K, Mandal, Sudeshna, Manders, Tracy, Manderson, Lauren, Mandeville, Justin, Mane, Tara, Manhas, Roope, Maniero, Carmen, Manikonda, Ravi, Manjra, Ilham, Mankiewitz, Rowan, Mann, Bobby, Manning, Jonathan, Manning, Sarah, Mannion, Pascoe, Mansi, Katherine, Manso, Katarina, Mansour, Dina, Mansour, Mohamed, Mansour, Ramy, Mapfunde, Isheunesu T, Mappa, Predeesh, Maqsood, Arrusaw, Maraj, Hemant, Marchand, Clare, Marcus, Neil, Marcyniuk, Anna, Marecka, Maria, Maren, Deborah, Margabanthu, Gomathi, Margalef, Jordi, Margarit, Lavinia, Margaritopoulos, Georgios, Margarson, Mike, Maria del Rocio, Fernandez, Maria Pfyl, Teresa, Mariano, Victor, Maric, Ashleigh, Markham, Grace, Marks, Ben, Marks, Maria, Marks, P, Marler, Emily, Marouzet, Elisabeth, Marriott, Arran, Marriott, Cheryl, Marriott, Nemonie, Marsden, Christopher, Marsden, Karen, Marsden, Paul, Marsden, Sarah, Marsden, Tracy, Marsh, Cathryn, Marsh, Glen, Marsh, Robyn, Marshall, Adam, Marshall, Andrew, Marshall, Gail, Marshall, Henry, Marshall, Jaimie, Marshall, Jenna, Marshall, Nicola, Marshall, Riley, Marshall, Steven, Marshall, Jennifer, Martin, Emmeline, Martin, Gaynor, Martin, Hayley, Martin, Hope, Martin, Jane, Martin, Karen, Martin, Kate, Martin, Laila, Martin, Martha, Martin, Michael, Martin, Noelia, Martin, Tim, Martin, Winston, Martin, Sarah, Martindale, Tim, Martineau, Marcus, Martinez, Lauren, Martinez Garrido, Jose C, Martin-Lazaro, Juan, Maruthamuthu, Vijay K, Marwan, Bukhari, Maryan, Gemma, Mary-Genetu, Roman, Maryosh, Sam, Masani, Vidan, Mascagni, Allison, Maseda, Diego, Maseko, Zandile, Mashate, Sheila, Mashhoudi, Yasaman, Mashta, Al, Masih, Izhaq, Masih, Sanna, Maskell, Nicholas, Maskell, Perry, Masoli, Matthew, Mason, Julia, Mason, Rebecca, Mason, Richard, Mason, Ruth, Mason, Claire, Masood, Mohammad, Masood, Mohammad T, Masood, Syed S M E, Massa, Thalia, Massey, Ian, Masters, Joseph, Masud, Aaqib, Matapure, Lear, Matei, Cristina, Matewe, Ropafadzo, Matharu, Manraj, Mathen, Stephy, Mather, Alex, Mather, Nicole, Mathers, Jonathan, Matheson, Joanna, Mathew, Amal, Mathew, Anna, Mathew, Bijoy, Mathew, Moncy, Mathew, Verghese, Mathews, Jesha, Mathias, Kate, Mathioudakis, Alexander, Matila, Darwin, Matimba-Mupaya, Wadzanai, Matin, Nashaba, Matisa, Elina, Matkins, Ellen, Matonhodze, Max, Matovu, Elijah, Mattappillil, Jaysankar, Matthews, Alison J, Matthews, Clive, Matthews, Heather, Matthews, Helen, Mattocks, Lehentha, Maughan, Charlotte, Mawson, Emma, Maxton, Fiona, Maxwell, Adam, Maxwell, Veronica, May, Emily, May, James, May, Joanne, May, Philippa, Mayanagao, Irving, Maycock, Matthew, Mayer, Jordan, Mayers, Graham, Maynard, Victoria A, Mayo, Thomas, Mayola, Lioniza, Mayor, Shelley, Mazen, Ibreaheim, Mazhani, Thamani, Mazzella, Andrea, Mburu, Nyambura, Mbuyisha, Angeline, Mc Cague, Celine, McAleese, Eleanor, McAlinden, Paul, McAllister, Lesley, McAlpine, Audrey, McAlpine, Graeme, McAndrew, Jonathan, McAuley, Hamish, McAuliffe, Sarah, McBrearty, Claire, McBride, Erin, McBuigan, Michael, McBurney, James, McCabe, Laura, McCafferty, Gemma L, McCafferty, Laura, McCairn, Amanda, McCammon, Jake, McCammon, Nicole, McCann, Conor, McCann, Erin, McCarrick, Alexandra, McCarron, Brendan, McCarthy, Eoghan, McCarthy, Michelle, McCarthy, Natalie, McCaughey, Sinead, McClay, Tara, McClelland, Beverley, McClintock, Declan, McCloskey, Michael, McCollum, Kirsten, McCorkindale, Alasdair, McCormack, Patricia, McCormick, Jacqueline, McCormick, Jake, McCormick, Wendy, McCourt, Paul, McCrae, Jame, McCready, Sharon, McCreath, Gordan, McCreedy, Helen, McCue, Claire, McCullagh, Iain J, McCullagh, Liz, McCullagh, Megan, McCullough, Conor, McCullough, Katherine, McCullough, Nicola, McCullough, Sarah, McCurrach, Fiona, McDermott, John, McDermott, Paula, McDermott, Rory, McDevitt, Katharine, McDill, Helen, McDonald, Basil, McDonald, Carly, McDonald, Claire, McDonald, Debbie, McDonald, Rob, McDonald, Sam, McDonald, Damhnaic, McDonnell, Natasha, McDougall, Catherine, McDougall, Lilly, McDougall, Rowan, McEleavy, Irene, McElwaine, Fred, McEntee, Julie, McEvoy, Evanna, McEwan, Claire, McEwen, Ruth, McFadden, Margaret, McFarland, Denise, McFarland, Margaret, McFarland, Rachel, McFlynn, Joe, McGarry, Erin, McGarvey, Lorcan, McGeachan, Alex, McGee, Frederick, McGenily, Laura, McGettigan, Clodagh, McGettrick, Michael, McGhee, Christopher, McGill, Fiona, McGinnity, Sarah, McGlinchey, Neil, McGlone, Phil, McGlynn, Deborah, McGoldrick, Claire, McGoldrick, Clare, McGough, Elizabeth, McGovern, Christopher, McGovern, Roisin, McGowan, Angela, McGown, Anne, McGrath, Brendan, McGregor, Amanda, McGregor, Annemarie, McGuigan, Michael P, McGuinness, Heather, McGuire, Sean, McHugh, Tara, McInnes, Caroline, McInnes, Neil, McIntosh, Jerome, McIntyre, Karen, McIntyre, Mhairi, McKay, Lorna, McKeag, Conor P, McKeane, Jacqueline, McKee, Madeleine, McKeever, Joseph, McKenna, Judith, McKenna, Shirley, McKenzie, Mary, McKeogh, Donogh, McKerr, Caroline, McKie, Anthony M, Mckie, Hayley, Mckie, Laura, McKnight, Gerard, McLachlan, Heather, McLaren, Andrew, McLaren, Barbara, McLarty, Nicola, Mclaughlan, Danielle, McLaughlin, Maria, McLay, James, McLeish, Mary, McLennan, Tina, McLure, Stewart, McMahon, Anne Marie, McMahon, Genevieve, McMahon, Mike, McMahon, Stephen, McManus, Terence, McMaster, Moyra, McMaster, Paddy, Mcmeeken, Faye, McMeekin, Samuel, McMillan, Nicola, McMillen, Katherine, McMinn, Jason, McMorrow, Liam, McMullen, Heather, McMurran, Christopher, McNally, Helen, McNeela, Fiona, McNeil, Lynne, McNeill, Claire, McNeill, Jessica, McNeill, Shea, McNelis, Una, McNulty, Melanie, McNulty, Roisin, McParland, Christopher, McPhail, Mark, McQueen, Alison, McSkeane, Anna, McSorland, Denise, McSorley, Therese, McTaggart, Gini, McTaggart, Jacqueline, Mead, Joanna, Mead, Paul, Meadows, Emma, Meakin, Olivia, Mearns, Ben, Mearns, Claire, Mears, Kim, Mears, William, Meda, Manjula, Mediana, Ayren, Medine, Ross, Medveczky, Thomas, Meehan, Sharon, Meeks, Emily, Megan, Abbi, Meghani, Nevan, Meghjee, Salim, Megson, Sharon, Mehar, Amina, Mehmood, Mehr N, Mehra, Rohan, Meirill, James, Meiring, James, Mejri, Rayane, Mekonnen, Ellen, Melander, Sabina, Melinte, Adriana-Stefania, Mellersh, Jennifer, Melling, Lucy, Mellish, Christie, Mellor, Francesca, Mellor, Joe S, Mellor, Samantha, Mellor, Zoe, Mellows, Katrina, Melnic, Vladimir, Melville, Alice, Melville, Dominique, Melville, Julie, Membrey, Helen, Mencias, Mark, Mendelski, Adam, Mendonca, Cheryl, Meney, Carron, Mensah, Winifred, Mentzer, Alexander, Menzies, Dan, Menzies, Sarah, Mepham, Sue, Mercer, Oliver, Mercer, Pauline, Merchant, Arwa, Merchant, Fatema, Mercioniu, Mihaela, Meredith, Megan, Merida Morillas, Marta, Merrick, Blair, Merritt, Jack, Merritt, Sharon, Merritt, Simon, Merron, Paul-Peter, Merwaha, Ekta, Message, Simon, Messenger, Jenny, Metcalf-Cuenca, Gabriel, Metcalfe, Alexandra, Metcalfe, Benjamin, Metcalfe, Kneale, Metherell, Stella, Metryka, Alexsandra, Mew, Louise, Meyrick, Simon, Mguni, Nhlanhla, Miah, Atiqa, Miah, Jagrul, Miah, Nahima, Mian, Areeb, Mic, Gabriela, Micallef, Dariush, Michael, Alice, Michael, Angiy, Michael, Shery, Michalak, Natalia, Michalca-Mason, Loredana, Michalec, Ola, Middle, Janet, Middleton, Hayley, Middleton, Jennifer T, Middleton, Maeve, Middleton, Sophie, Mieres, Shelley, Mihalca-Mason, Loredana, Mikolasch, Theresia, Milgate, Sarah, Millar, Colin, Millar, Jonathan, Millard, James, Miller, David, Miller, Johnathan, Miller, Lucy, Miller, Rachel, Miller-Biot, Naomi, Miller-Fik, Alex, Millett, Louise, Milligan, Barry, Milligan, Hazel, Milligan, Iain, Milliken, Caitlin, Millington, Katherine, Millington, Rhys, Millington, Samuel, Mills, Helen, Mills, Janet, Mills, Rebecca E, Millward, Helen, Miln, Rebecca, Milne, Alice, Milne, Charlotte, Milne, Louise, Milner, Joanne, Milner, Leanne, Min, Zayar, Mindel, Samuel, Minnis, Chrissie, Minnis, Paul, Minou, Konstantina, Minskip, Natalie, Minton, Jane, Miranda, Frederico, Mirela, Mukaj, Mirza, Taimur, Misbahuddin, Anjum, Mishra, Aseem, Mishra, Biswa, Mishra, Eleanor, Mishra, Ritu, Misra, Sannidhya, Mistry, Deena, Mistry, Heena, Mital, Dushyant, Mitchard, Sarah, Mitchell, Ben, Mitchell, Caroline, Mitchell, Luke J, Mitchell, Piers, Mitchelmore, Philip, Mitra, Andrew, Mitra, Atideb, Mitra, Sandip, Mlambo, Nomsa, Moakes, Emma, Moar, Kirsten, Moatt, Emma, Mock Font, Daniela, Modgil, Gita, Mohamed, Abdelrahman, Mohamed, Arez, Mohamed, Osab, Mohammad, Akram, Mohammad, Waheed, Mohammed, Aliabdulla, Mohammed, Omer, Mohammed, Yaser N S, Mohamud, Bilal A, Moharram, Amr, Mok, Hoi-Ping, Mok, Jonathan, Mokogwu, Leslie, Molina, Marcelino, Moller-Christensen, Christine, Mollet, Mateus, Molloholli, Malid, Molloy, Aoife, Molloy, Linda, Molyneux, Andrew, Molyneux, Rebekah, Momoniat, Tasnim, Monaghan, Holly, Monaghan, Krista, Mongolu, Shiva, Monika, Tesha, Monsell, Katelyn, Montasser, Mahmoud, Montgomery, Alan, Montgomery, Hugh, Moodley, Prebashan, Moody, Margaret, Moody, Nick, Moon, Angela, Moon, James, Moon, Ji-Hye, Moon, Maria, Moonan, May, Moondi, Parvez, Moorby, Suzanne, Moorcroft, Jim, Moore, Alex, Moore, Christopher, Moore, David A J, Moore, Faye, Moore, Judith, Moore, Laura, Moore, Natalie, Moore, Sally, Moore, Siobhan, Moore, Sonia, Moore, Vanessa, Moores, Rachel, Morab, Ed, Morales, Jose, Moramorell, Nuria, Moran, Louise, Moray, Grishma, Moreno-Cuesta, Jeronimo, Morgan, Alexander, Morgan, Amy, Morgan, Caitlin, Morgan, Christine, Morgan, Colin, Morgan, Holly, Morgan, Katie, Morgan, Lauren, Morgan, Leila, Morgan, Lewis, Morgan, Matthew, Morgan, Patrick, Morgan-Jones, Katie, Morgan-Smith, Emily, Morilla, Joseph, Morley, Anna, Morley, Thomas, Morley, Wendy, Morris, Anna, Morris, Damian, Morris, Fiona, Morris, Helen, Morris, Juliet, Morris, Katie, Morris, Laura, Morris, Lucy, Morris, Mary-Anne, Morris, Niall, Morris, Paul, Morris, Sheila, Morris, Susan, Morrison, Douglas, Morrison, Moira, Morrison, Scott, Morrissey, Mary, Morrow, Abbie C, Morrow, Anna, Morselli, Franca, Mortem, Gordon, Mortland, Valerie, Morton, Chelsea, Morton, Gordon, Morzaria, Priti, Mosby, Daniel, Moseley, Linda, Moshal, Karyn, Moshy, Ben, Moss, Alison, Moss, Charlotte, Moss, James, Moss, Sarah, Moss, Stuart, Mostafa, Omar, Moth, Georgia, Motherwell, Nicki, Mottershaw, Sharon, Moudgil, Harmesh, Mouland, Johanna, Moulds, Caroline, Moulton, Hilary, Mounce, Ginny, Mousley, Elizabeth, Mowatt, Chris, Moxham, Karen, Moya, Borja, Moyo, Quberkani, Mshengu, Eunice, Mtuwa, Sheila, Muazzam, Ali, Muazzam, Iqtedar A, Muchenje, Nykki, Mudawi, Dalia, Muddegowda, Girish, Mufti, Rabia, Mugal, Imran, Mughal, Ahsan, Muglu, Javaid, Muhammad, Fawad, Muhammad, Javed, Muir, Carol, Mukherjee, Aparna, Mukherjee, Dipak, Mukhtar, Jameel, Mukhtar, Syed A A, Mukimbiri, Denise, Mulcahy, John, Mulcahy, Michelle, Mulgrew, Peter, Mulhearn, Ben, Mulla, Arafat, Mullan, Dee, Mullasseril Kutten, Dileepkumar, Mullen, Niall, Mullett, Rosemary, Mulligan, Ciara, Mulligan, Sandra, Mumelj, Lana, Mumford, Andrew, Munavvar, Mohammed, Munby, Henry, Munday, Hannah, Munro, Anne-Marie, Munt, Sheila, Mupudzi, McDonald, Murad, Arshid, Muraina, Oluwatosin H, Muralidhara, Koteshwara, Murdoch, Mhairi, Murira, Jennifer, Murphy, Alison, Murphy, Ben, Murphy, Carl, Murphy, Cathal, Murphy, Erin, Murphy, Gail, Murphy, Hannah, Murphy, Peter, Murphy, Rebecca, Murphy, Sheenagh, Murphy, Simon, Murphy, Alison, Murray, Clare, Murray, David, Murray, Dawn, Murray, Eleanor, Murray, Katie, Murray, Kenneth, Murray, Lindy, Murray, Lisa, Murray, Lorna, Murray, Tracey, Murtagh, Eoin, Murthy, Mithun, Murton, Catherine, Murton, Rosie, Muru, Neeka, Musanhu, Rosemary, Mushabe, Maimuna, Mushtaq, Omaisa, Mustafa, Ahmed M M, Mustafa, Elhaytham, Mustafa, Mustafa, Mustapha, Ibrahim, Mustfa, Naveed, Mustufvi, Zhain, Mutch, Callum, Mutch, Rachel, Mutema, Eric, Muthukrishnan, Balakumar, Mutton, Sheree, Muzengi, Natasha, Mwadeyi, Memory, Mwale, Bettina, Mwaura, Esther, Myagerimath, Raji, Myers, Alice, Myers, Sam, Myerson, James S, Myint, Khin Swe, Myint, Yadee, Mynott, Georgina, Myslivecek, Libor, Nabayego, Patricia, Nadar, Evelyn, Nadeem, Iftikhar, Nadheem, Moosa, Nadjm, Behzad, Naeem, Asma, Naeem, Hassan, Naeem, Salman, Nafees, Samraiz, Nafei, Mohamed, Nagarajan, Thapas, Naglik, Leah, Nagra, Imrun, Nagra, Deepak, Naguib, Mina, Naguleswaran, Kirushthiga, Nagumantry, K Shonit, Naicker, Kevin, Naidoo, Sarveshni, Naik, Gireesha, Naik, Rishi, Naik, Samir, Nair, Devu S, Nair, Rajiv, Nair, Tanushree, Naisbitt, Jay, Naismith, Kerry, Nakiboneka-Ssenabulya, Deborah, Nallapareddy, Sri, Nallapeta, Soum, Nallasivan, Arumugan, Nanda, Uttam, Nandani, Aarti, Nandwani, Tara, Naqvi, Ali Raza, Naqvi, Asadullah, Naqvi, Sara, Nasa, Sophia, Nash, Dominic, Nasheed, Nader, Nasimudeen, Abdul, Nasir, Umer, Nasser, Tahir, Natarajan, Anuja, Natarajan, Geetha, Natarajan, Nalin, Natarajan, Nikhila, Natarajan, Rajkumar, Nath, Preethy, Nathaniel, Noel, Nathvani, Mala, Nathwani, Priyan, Nava, George, Navaneetham, Neena, Navaratnam, Jeya, Navarra, Helen, Naveed, Sadaf, Navin, John, Nawaz, Khuteja, Nawaz, Sarfaraz, Nawaz, Shasta, Nayar, Bonilla, Naylor, Suzanne, Nayyar, Moez, Naz, Farrah, Naz, Mobeena, Nazari, Babak, Nazir, Abida, Nazir, S, Nazir, Sehar, Ncomanzi, Dumisani, Ndefo, Onyinye, Ndoumbe, Narcisse B, Neal, Abigail, Neal, Alan, Neary, Elaine, Negmeldin, Mostafa, Neil, Jonathan, Neill, Paula, Neils, Hector E, Nejad, Avideah, Nel, Jeremy, Nel, Louise, Nelson, Benjamin, Nelson, Lauren, Nelson, Marie, Nelson, Memory, Nelson, Richard, Nelson, Scott, Nelson, Sven, Nelwan, Erni, Nemane, Rajesh, Nepal, Samiksha, Nethercott, Daniel, Netherton, Kimberley, Nettleton, Kimberley, Newby, Alison, Newby, Angela, Newby, David, Newcombe, Tracy, Newell, Helen, Newman, Charlotte, Newman, Diana, Newman, Hannah, Newman, Julie, Newman, Oscar, Newman, Tabitha, Newman, Thomas, Newport, Rachel, Newton, Maria, Ng, Anthony Y K C, Ng, Hui E J, Ng, Ka Wing, Ng, Maxine, Ng, Sarah, Ng, Wee Jin, Ng, Yee W M, Ngan, Thomas, Ngui, Gabriel CE, Ngumo, Alice, Nguyen, Quang, Ngwenya, Keith, Nic Fhogartaigh, Caoimhe, Nicholas, Nathalie, Nicholas, Philip, Nicholas, Rachel, Nicholas, Rebecca, Nicholls, Donna, Nicholls, Lisa, Nicholls, Sarah, Nicholson, Alice, Nicholson, Anne, Nicholson, Annette, Nickson, Ian, Nicol, Eileen, Nicol, Elizabeth, Nicol, Rebecca, Nicola, Pantelis, Nicoll, Antony, Nightingale, Tania, Nikita, Faria, Nikolaos, Pantzaris, Nikonovich, Georgii, Nilsson, Annette, Nimako, Kofi, Nimako, Louise, Nimmo, Camus, Ninan, Preethy, Nirmalan, Mahesh, Nisar, Attiya, Nisar, Muhammad, Nisar, Tosia, Nisbett, Toby, Nisha James, Aksinya, Nishat, Sabaahat, Nishiyama, Tomoko, Nix, Sara, Nixon, Jennifer, Nixon, Maxine, Nizam Ud Din, Khwaja, Nizami, Maria, Nizamis, Serafeim, Njafuh, Raymond, Noakes, India, Noba, Lyrics, Noble, Jennifer, Noble, Jonathan, Noble, Harriet, Noe, Hsu M, Nolan, Jerry, Nolasco, Jackson, Noor, Zahid, Noori, Zaid, Norcliffe, Jayne, Norman, Louis, Norman, Rachel, Norris, Emma, Norris, Karen, Norris, Lillian, Nortcliffe, Sally Ann, North, Fiona, North, Julie, North, Thomas, Northfield, John, Northover, Samantha, Nortje, Jurgens, Norton, Donna, Norton, Rowen, Notman, Holly, Nourein, Khalid, Novak, Timea, Novas Duarte, Nuria, Novis, Catherine, Nowak, Justyna A, Nu, Khin Phwe, Nugdallah, Mohamed, Nugent, Anne M, Nugent, Justine, Numbere, Numbere, Nundlall, Kribashnie, Nune, Arvind, Nunn, Kieran, Nunn, Michelle, Nunnick, Jane, Nupa, Yvonne, Nur, Fadumo, Nurgat, Zubeir, Nuttall, Amy, Nwafor, Lorenza, Nwajiugo, Paul C, Nyamugunduru, Godfrey, Nyirenda, Maggie, Nyland, Kerry, O Rinn, Donal, O Shea, Daire, O Toole, Megan, O'Hara, Marianne, O'Hara, Chloe, O'Keefe, Laura, O'Reilly, Kevin, O'Rourke, William, Oakley, Caroline, Oakley, Naomi, Oakley, Susan, Obale, Begho, Oboh, Clements, O'Brien, Clare, O'Brien, Julie, O'Brien, Kirsty, O'Brien, Linda, O'Brien, Neale, O'Brien, Rachel, O'Brien, Tracey, O'Bryan, Emma, Obukofe, Ross, O'Callaghan, Christopher, O'Connell, Lorcan, OConnor, Tadg, O'Connor, Chris, O'Connor, Grainne, Odam, Miranda, Oddie, Sam, Oddy, Sharon, Odedina, Yejide, Odedra, Krishma, Odelberg, Sven W, Odell, Natasha, Oderinde, Omolola, Odone, Jessica, O'Donohoe, Lynn, O'Donovan, Catherine, Odysseos-Beaumont, Isabel, O'Farrell, Stephen, Offord, Pamela, O'Flaherty, Morgan, Ogbara, Tanwa, Ogilvie, Catherine, O'Gorman, Ciaran, Ogunjembola, Ibrahim, Ogunkeye, Oluwatomilola, Ohia, Udeme, Ojha, Shalini, Ojha, Sushma, Ojhas, Sushma, Ojo, Ohiowele, O'kane, Fiona, O'Kane, Mark, Okeke, Tolu, OKell, Eleanor, Okines, Alicia, Okpala, Iheoma, Okpo, Ernest, Okpoko, F, Okubanjo, Maryanne, Oladipo, Chiamaka, Olaivar, Liel A, Olaiya, Raphael, Olatujoye, Jacob, Old, Tim, Oleszkiewicz, Gregory, Oliver, Annie, Oliver, Catherine, Oliver, Jesse, Oliver, Lucinda, Oliver, Martyn, Oliver, Zoe, Olokoto, Nurudeen O, Olonipile, Folusho, Olufuwa, Olumide, Olukoya, Olatomiwa, Oluwole-Ojo, Akinlolu, O'Malley, Laura, Omar, Maryam, Omar, Mohamad, Omar, Zohra, Omer, Nimca, Omoregie, Eti, O'Neill, Connaire, O'Neill, Lauran, Ong, Chon S, Onuoha, Onyinye, Onyeagor, Chidera, Oo, Chan N, Oo, Zin N, Ooi, Huah C, Ooi, Sze H, Oomatia, Amin, Opena, Maria, Oram, Richard, Ord, Christy, Ord, Jonathan, Oreilly, Clare, Orekoya, Lola, O'Riordan, Devaki, O'Riordan, Sean, Orlikowska, Izabela, Orme, Amy, Orme, Hannah, O'Rourke, Laura, Orr, Charlotte, Orr, Sarah, Orton, Christopher, Osadcow, Anna, Osagie, Rawlings, Osanlou, Rostam, Osborne, Lynn, Osborne, Nigel, Osborne, Rebecca, Osborne, Wendy, Osborne, William, Osbourne, Charles, Osei-Bobie, Jennifer, Osman, Joseph, Osman, Wa'el, Osman, Bashir, Osoata, G, Ostermann, Marlies, O'Sullivan, Eoin, O'Sullivan, Susan, Otey, Noor, Otite, Otheroro K., O'Toole, Marie, Ouyang, Jingxiu, Owen, Rachel, Owen, Stephanie, Owens, Emma, Owoseni, Yetunde, Owston, Michael, Oxlade, Ruth, Ozdes, Feray, Pack, Jamie, Packham, Alice, Packham, Sophie, Paczko, Piotr, Padden, Grace, Padmakumar, Anand, Page, Catrin, Page, Iain, Page, Joseph, Page, Shannon, Page, Valerie, Paget, Jodi, Pagett, Katherine, Paisley, Lee, Pajak, Susannah, Pajak, Susie, Pakou, Glykeria, Pakozdi, Angela, Pal, Soubhik, Pal, Sushi, Palacios, April, Palagiri Sai, Vishnu B, Palaniappan, Vadivu, Palanivelu, Priya, Palfreeman, Adrian, Palfrey, Heather, Palissery, Vinod, Palit, Deepshikha, Pallipparambil Antony, Sherly, Palman, Jason, Palmer, Alistair, Palmer, Helen, Palmer, Janet, Palmer, Lynne, Palmer, Ross, Pambouka, Andrea, Pamphlett, Ian, Pan, Daniel, Pandey, Anmol, Pandian, Nithya, Pandya, Krishnaa, Pandya, Tej, Panes, Alice, Pang, Jessica, Pang, Yee Wei, Pannell, Laura, Pannu, Kanwar, Pant, Suman, Panthakalam, Sathianathan, Pantin, Charles T, Pao, Norman, Papaconstantinou, Helen, Papineni, Padmasayee, Paques, Kitty, Paracha, Abdul W, Paradowski, Kerry, Parambil, Vinay, Paranamana, Supathum, Parashar, Siddhant R, Parberry, Ian, Parekh, Amy, Parekh, Dhruv, Parfitt, Louise, Parfrey, Helen, Parikh, Omi, Parish, Gemma, Park, John, Parkash, Vivak, Parker, Angela, Parker, Ben, Parker, Emma, Parker, Helen, Parker, Jacob, Parker, Julie, Parker, Laura, Parker, Lucy, Parker, Natasha, Parker, Nicola, Parker, Sara, Parker, Sean, Parkin, Kirstin, Parkinson, Anna, Parkinson, Molly, Parkinson, Valerie, Parmar, Chetan, Parmar, Viraj, Parris, Victoria, Parrish, Chloe, Parry, Bethan, Parry, Helen C, Parslow-Williams, Siobhan, Parsonage, Maria, Parsons, Georgie, Parsons, Joseph, Parsons, Penny, Partridge, Richard, Parvez, Zeeshan, Parvin, Kevin, Passby, Lauren, Passey, Samuel, Passmore, Heather, Pastrana, Juan, Patachako, Jonathan, Patal, Mital, Patch, Sarah, Patel, Aamie, Patel, Alkesh, Patel, Amisha, Patel, Bijal, Patel, Dakshesh, Patel, Darshna, Patel, Hemani, Patel, Jaymik, Patel, Kamal, Patel, Kayur, Patel, Kiran, Patel, Krish, Patel, Manish, Patel, Margi, Patel, Martyn, Patel, Mehul, Patel, Naleem, Patel, Nehalbhai, Patel, Prital, Patel, Saagar, Patel, Sanjay, Patel, Soonie, Patel, Trishna, Patel, Zaakirah, Patel, Vishal, Paterson, Kirsteen, Pathak, Sangeeta, Pathan, Nazima, Patience, Alexandra, Patience, Donna, Patmore, Russell, Patole, Sonia, Paton, Lia, Patrick, Abigail, Patrick, Georgie, Patrick, Jean, Patten, Simon, Pattenden, Ben, Patterson, Charlotte, Patterson, Jean, Patterson, Linda, Patterson, Molly, Patterson, Robert, Pattrick, Martin, Paudel, Kamala, Paudel, Manu, Paudel, Suman, Paul, Moriarty, Paul, Suman, Pauls, Leigh, Paulus, Stephane, Pavely, Amelia, Pavitt, Matthew J, Pavord, Susan, Payne, Brendan, Payne, Elizabeth, Payne, Mark, Payne, Ruth, Peacock, Linda, Peacock, Louise, Peacock, Sarah, Peake, Henry, Pearce, Jasmine, Pearse, Rachel, Pearse, Rupert, Pearson, Andrew, Pearson, Daniel, Pearson, Harriet, Pearson, Karen, Pearson, Samuel A, Pearson, Sandra, Peasley, Alice, Peddie, Hilary, Peebles, Steven, Peek, Russell, Peer, Adam, Peerbhoy, Shahid, Pegg, Claire, Peggie, Eleanor, Peggie, Hannah, Peglar, Suzannah, Peirce, Benjamin H, Peirse, Mary, Pelham, Claire, Pemberton, Abigail, Penacerrada, Melchizedek, Pender, Anthony, Pendlebury, Carmel, Pendlebury, Jessica, Penfold, Rachel, Penman, Catherine, Penman, Julie, Penman, Rachel, Penner, Justin, Penney, Kristi, Pennington, Anna, Penny, James, Pepperell, Justin, Percival, Rachel, Pereira, Adriana, Pereira, Rita, Pereira Dias Alves, Carlota, Perera, Indika, Perera, Marek, Perez, Elena, Perez, Jane, Perinpanathan, Tanaraj, Periyasamy, Lakshmi, Perkins, Emma, Pernicova, Ida, Perritt, Elizabeth, Perry, Alice, Perry, Alison, Perry, Emily, Perry, Meghan, Perumpral, Thomas M, Pessoa-Amorim, Guilherme, Petch, Ruth, Peter, Lionel, Peters, Cecilia, Peters, Lucy, Peters, Mark, Peters, Steve, Peters, Tim, Petersen, Remy, Peterson, Alexandra, Peto, Leon, Petras, Iulia, Petrova, Boyanka, Petrova, Mirela, Petrovics, Ellen, Pettigrew, Tom, Pezard-Snell, Marius, Pfeffer, Paul, Phalod, Gunjan, Phanish, Mysore, Phelan, Paul, Philbey, Christopher, Philbin, Jennifer, Phillips, Aled, Phillips, Alex, Phillips, Bethan, Phillips, Dylan, Phillips, Nicola, Phillips, Patrick, Phillips, Rachael, Phillips, Thomas, Phipps, Marie, Phipps, Michael, Phongsathorn, Virach, Phull, Mandeep, Phuyal, Anita, Phyo, Aye Kyaw, PI, Myat T T, Pick, Sara, Pickard, James, Pickering, Charlotte, Pickering, Frances, Pickering, Gillian, Pickett, Thomas, Pickles, Joanna, Pickstock, Shirley, Pickwell-Smith, Benjamin, Pieniazek, Natalia, Piercy, Charlie, Pieris, Angelo, Pilgrim, Samia, Pillai, Paul A, Pilling, Laura, Pilsworth, Zoe, Pinches, Heather, Pinches, Stacey, Pine, Kirsty, Pinjala, Muni T, Pintus, Stefania, Piper, Graeme, Pirani, Tasneem, Pitchford, Marie, Pittman, Marcus, Pitts, Sally, Plaatjies, Nicolene, Platt, Naomi, Pleass, Robert, Plowright, Megan, Plummer, Laura, Plumptre, Charles, Pobjoy, Jonathan, Pogreban, Tatiana, Poku, Stephen, Polgarova, Petra, Pollard, Rachel, Pollock, Louisa, Poluyi, Oluwamayowa, Polwarth, Gary John, Pomery, Fiona, Ponce, Ida M F, Ponnusamy, Ponmurugan, Ponnusamy, Suresh, Ponnuswamy, Aravind, Ponte Bettencourt dos Reis, Inês, Pooboni, Suman, Poole, Alice, Poole, Lynda, Poole, Michele, Poon, Sharon, Poonian, Tajinder, Porteous, Jack, Porteous, Mark, Porter, David, Porter, Jo, Porter, Linda, Porter, Ross, Posada, Anna, Postlethwaite, Kelly, Potdar, Manoj, Pothecary, Carla, Pothina, Narayana, Potla, Priyadarshan, Potoczna, Dorota, Pott, Jason, Potter, Alison, Potter, Andrew, Potter, Jean, Potter, Sarah, Potter, Tracey, Potton, Elspeth, Potts, Joanne B, Potts, Julie, Potts, Kathryn, Poudyal, Beli, Poultney, Una, Poulton, Katherine, Poustie, Vanessa, Powell, James, Powell, Jordan, Powell, Natassia, Powell, Sandra, Power, Deborah, Power, Nick, Power, Sharon, Poxon, Joseph, Poyner, Emma, Poyner, Robin, Prabhu, Aishwarya, Prabowo, Sandhi, Pradhan, Vidushi, Pradip, Gyanwali, Prady, Helena, Prasad, Aalekh, Prasad, Krishna, Prasad, Usha, Prasanth Raj, Fredy, Prasath, Sangeetha, Prately, Anezka, Pratiwi, Nicky G, Pratt, Steven, Preiss, David, Prendergast, Claire, Prentice, Lynn, Prentice, Peter, Prescott, Verity, Presland, Laura, Prest, Catharine, Preston, Stephen, Pretorius, Martha, Prevatt, Natalie, Prew, Sandra, Price, Ashley, Price, Carly, Price, Claire, Price, David, Price, Elizabeth, Price, Katie, Price, Laura J, Price, Nathan, Price, Vivien, Price-Eland, Rachael, Priest, Anne, Prieto, Jimena, Primrose, Lorraine, Prince, Clare, Prince, John, Prince, Judith, Prince, Laura, Pringle, Shirley, Prior-Ong, Melissa, Pristopan, Veronika, Pritchard, Kelly, Pritchard, Lucy, Pritchard, Simon, Priyash, Verma, Procter, Andrew, Proctor, Clare, Protopapas, Mike, Proudfoot, Rebecca, Prudon, Benjamin, Pryor, David, Pudi, Solomon, Puffett, Angela, Pugh, Joanne, Pugh, Lawrence, Pugh, Mark T, Pugh, Nichola, Pugh, Richard, Puisa, Veronika, Puliyakkadi, Safa, Pullen, Jennifer, Punia, Kirandip, Punnilath Abdulsamad, Saleel, Purandare, Laura, Purchase, Daniel, Purdue, Corrina, Purdy, Rachel, Purewal, Bally, Purnell, Rebecca, Pursell, Molly, Purssord, Gregory, Purves, Rory, Purvis, Sarah, Puspatriani, Khairunnisa, Putensen, Daniel, Puvaneswaran, Bhamini, Puxty, Alex, Puxty, Kathryn, Puyrigaud, Zoe, Pyart, Eleanor, Pye, Emily, Pynn, Michael, Qadeer, Tariq, Qayum, Mohammad, Quah, Corrine, Quaid, Sheena, Quail, Nathaniel, Quamina, Charlotte, Quartermaine, Georgia, Quasim, Tara, Quayle, Alice, Quek, Eleanor, Quenby, Siobhan, Qui, Xinyi, Quick, Vanessa, Quigley, Julie, Quijano-Campos, Juan-Carlos, Quindoyos, Jhanielle, Quinn, Andrew, Quinn, James, Quinn, Tom, Quratulain, Quratulain, Qureshi, Danya, Qureshi, Ehsaan, Qureshi, Hasanain, Qureshi, Iram, Qureshi, Khadija, Qureshi, Nawaz, Qurratulain, Qurratulain, Qutab, Saad, Rabbani, Muhammad S, Rabinowicz, Simon, Raceala, Madalina, Rachid, Alan, Rachman, Raissa, Rad, Laura, Radford, Jane, Radford, Liz, Radhakrishnan, Jayachandran, Rafferty, Hannah, Rafiq, Muhammad Y, Rafiq, Shabana, Rafique, Cecillia, Rafique, Jethin, Rafique, Muhammad, Ragatha, Ravi, Raghunathan, Aiswarya, Raguro, Abigail, Raha, Shankho D, Rahama, Sana, Rahardjani, Mutia, Rahilly, Karen, Rahim, Faisal, Rahimi, Abdul H, Rahimi, Haseena R, Rahman, Muhammad, Rahman, Salim Ur, Rahmany, Sohail, Rai, Prajan, Rai, Sabi, Rai, Supriya, Raisova, Lenka, Raithatha, Ajay, Raj, Arjun, Rajagopal, Anithya, Rajagopalan, Pradeep, Rajaiah, Nithy, Rajalingam, Kanendran, Rajasekaran, Arvind, Rajasri, Aylur, Rajbhandari, Sagar, Rajeswaran, Thurkka, Rajeswary, Jyothi, Rajkanna, Jeyanthy, Rajkumar, Indhuja, Rajmohan, Gayathri, Rallan, Ruth, Ralston, Katherine, Ralston, Maximilian, Ram, Matsa, Ramabhadran, Balaji, Ramali, Fathima, Ramali, Mohamed, Ramanan, Athimalaipet, Ramanna, Shashikira, Ramasamy, Maheshi, Rambe, Irfah, Ramchandani, Aradhana, Ramdin, Dhanishta, Ramirez, Jozel, Ramirez, Mylah, Ramnarain, Geshwin, Ramnarine, Amrita, Ramos, Lidia, Rampling, Tommy, Ramraj, Shanthi, Ramsay, Janine, Ramshaw, Alex, Rana, Aleem, Rana, Ghulam F, Rana, Naeem, Rana, Rehman, Rand, Abby, Rand, James, Randheva, Harpal, Ranga, Poonam, Rangar, Manmeet, Rangarajan, Harini, Ranjan, Sameer, Rank, Hannah, Ranka, Poormina, Rankhelawon, Rajesh, Rankin, Alastair, Rao, Anita, Rao, Sandhya, Rao, Sanjay, Rao, Deepak, Rasheed, Althaf Abdul, Rashid, Khalid, Rason, Madeleine, Raspa, Valentina, Rastogi, Somil, Rasul, Fazila, Ratcliff, Simbisai, Ratcliffe, Sam, Ratcliffe, Sophy, Rath, Priti, Rath, Sanjeev, Rather, Mohmad I, Rathod, Krishnaraj, Rathore, Selina, Ratnakumar, Aravinden, Ratoff, Jonathan, Rattehalli, Deepa, Ravaccia, Davide, Raval, Malvi, Ravencroft, Phil, Raw, Jason, Raw, Rachael, Rawal, Manisha, Rawashdeh, Sulaiman A, Rawlins, Hywel, Ray, Gautam, Raymond-White, Adam, Raynard, Dana, Rayner, Helen, Rayner, Nicola, Raynsford, Amy, Razvi, Salman, Razvi, Zarine, Read, Kerry, Read, Sarah, Reay, Michael, Reddington, Anne, Reddy, Ajay, Reddy, Anvesh, Reddy, Harsha, Redfearn, Heidi, Redfern-Walsh, Aine, Redknap, Ianto, Redman, Nell, Redome, Alex, Redome, Joan, Reed, Anna, Reed, John, Rees, Andrew, Rees, Caitlin, Rees, James, Rees, Martyn, Rees, Sarah, Rees, Stephanie, Rees, Tabitha, Rees-Jones, Elinor, Regan, Fiona, Regan, Karen, Regan, Martin, Regan, Susan, Rege, Kanchan, Rehan, Ahmed, Rehman, A, Rehman, Hafiz, Rehman, Shoib, Rehman, Zainab, Reid, Ada, Reid, Andrew, Reid, Jennifer, Reid, Jeremy, Reid, Sharon, Reilly, Mkyla, Reilly, Sharon, Reith, Christina, Reka, Arisa, Remegoso, Alda, Rengan, Dinakaran, Renouf, Louise, Renshaw, Stephen, Renu Vattekkat, Remya, Reschreiter, Henrik, Revels, Mark, Revill, Adam, Rewitzky, Glynis, Rey, Severine, Reynard, Charles, Reynish, Dominic, Reynolds, Heather, Reynolds, Peter, Reynolds, Piero, Rhodes, Jonathan, Riaz, Naghma, Ribeiro, Patricia, Rice, Emily, Rice, Matthew, Rice, Natalie, Rich, Mel, Richards, Alex, Richards, Alison, Richards, Liz, Richards, Suzanne, Richardson, Celia, Richardson, Emma, Richardson, Fiona, Richardson, Jamie, Richardson, Julie, Richardson, Madeleine, Richardson, Neil, Richardson, Nicky, Riches, Joanne, Riches, Katie, Richmond, Leah, Richmond, Ruth, Ricketts, William, Rickman, Hannah, Riddell, Anna, Ridgway, Stephanie, Ridha, Mohamed, Ridley, Carrie, Ridley, Paul, Rieck, Gudrun, Rigby, Linsey, Rigby, Myckala, Rigler, Daniel, Rijal, Samita, Rika, Nur, Riley, Hannah, Riley, Matthew, Riley, Phil, Rimainar, Atika, Rimba, Zwesty V P, Rimmer, Dominic, Rintoul, Robert, Riordan, Andrew, Ripley, David, Rippon, Naomi, Rishton, Chloe, Riste, Michael, Ritchie, David, Ritchie, Jane, Ritchings, Andy, Rivera Ortega, Pilar, Rivers, Vanessa, Rizvi, Batool, Rizvi, Syed A S, Rizvi, Syed H M, Robb, James, Robbins, Edel, Roberts, Gareth, Roberts, Ian, Roberts, Jane, Roberts, Jean, Roberts, Karen, Roberts, Mark, Roberts, Nicky, Roberts, Philip, Roberts, Rebecca, Roberts, Victoria, Robertson, Calum, Robertson, James, Robertson, Jamie, Robertson, Kirsten, Robertson, Nichola, Robertson, Stuart, Robertson, Mhairi, Robin, Nicole, Robinson, Caroline, Robinson, Emma, Robinson, Gisela, Robinson, Hannah, Robinson, Jemima, Robinson, Kate, Robinson, Liz, Robinson, Matthew, Robinson, Nicky, Robinson, Richard, Robinson, Ryan, Robinson, Sandra, Robinson, Alexandra, Robson, Steve, Roche, Lisa, Roche, Samantha, Rodden, Natalie, Roddick, Alistair, Roddy, Elin, Roddy, Jack, Roderick, Marion, Rodger, Alison, Rodger, Faye, Rodger, Megan, Rodger, Michael, Rodger, Megan, Rodgers, Alicia, Rodgers, Deirdre, Rodgers, Natasha, Rodgers, Penny, Rodriguez-Belmonte, Rocio, Roe, Nicholas, Roehr, Charles, Roehr, Charles, Rogers, Gill, Rogers, Jason, Rogers, Joanne, Rogers, John, Rogers, Leigh, Rogers, Lindsay, Rogers, Michaela, Rogers, Paula, Rogers, Susan, Rogers, Thomas, Rogers, Paula, Rojkova, Jana, Rokadiya, Sakib, Rollins, Lee, Rollo, Jennifer, Rolls, Catherine, Rond-Alliston, Alexander, Rook, Claire, Rooney, Kevin, Rooney, Lynsey, Rosaroso, Lace P, Rosby, Emily J, Rose, Abigail, Rose, Alastair, Rose, Annie, Rose, Steve, Rose, Zoe, Rosier, Josephine, Roskilly, Anna, Ross, Gavin A, Ross, Isobel, Ross, Jack, Rossdale, Jennifer, Ross-Parker, Andrew, Rostron, Anthony, Rothman, Alex, Rothwell, Joanne, Roughley, Lindsay, Rourke, Catherine A, Rowan, Kathryn, Rowan, Neil, Rowan, Stephen, Rowe, Anna, Rowe, Nicola, Rowe-Leete, Louise, Rowlands, Benjamin, Rowlands, Elen, Rowley, Megan, Roy, Subarna, Roycroft, Matthew, Roynon-Reed, Anna, Royson, Ann R, Rozewicz, Sam, Rudenko, Anna, Rudrakumar, Senthan, Rudran, Banu, Ruff, Shannon, Rughani, Prita, Rule, Rory, Rundell, Sharon, Rushforth, Eve, Rushmer, Jeremy, Rusk, Darren, Russell, Peter, Russell, Richard, Russo, Cristina, Rutgers, Marieke, Rutkowski, Krzysztof, Ryan, Aidan, Ryan, Brendan, Ryan, Kathryn, Ryan, Lucy, Ryan, Matthew, Ryan, Pat, Ryan, Phil, Ryan-Wakeling, Declan, Rybka, Elena, Ryder, Maggie, Ryder, Sophie, Saad, M, Saalmink, Gwendolyn, Sabale, Javeson, Sabaretnam, Suganya, Sadiq, Noman, Sadler, Emma, Saffy, Ashiq, Sage, Beth, Sagoo, Harkiran, Sagrir, Sobia, Saha, Rajnish, Saha, Sian, Sahdev, Nikhil, Sahedra, Sarvjit, Sahota, Jagdeep, Said, Nooria, Saini, Shalini, Saint, Bryony, Sajid, Anam, Sakthi, Sreekanth, Sakuri, Hikari, Saladi, Murthy, Salam, Abdul, Salberg, Armorel, Salciute, Erika, Saleeb, Gina, Saleh, Mumtaz, 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Gemma, Sharp, Kerry, Sharp, Louise M, Sharratt, Paula, Sharratt, Phoebe, Sharrocks, Katherine, Shashaa, Serene, Shaw, Alexandra, Shaw, Christopher, Shaw, Daisy, Shaw, David, Shaw, Deborah, Shaw, Joanne, Shaw, Jonathon, Shaw, Lisa, Shaw, Michele, Shaw, Tomos G, Shawcross, Anna, Shawcross, James, Shawe, Jill, Shayler, Lou, Shedwell, Sophy, Sheffield, Jonathan, Shehata, Zak, Sheik, Arshiya, Sheikh, Asif, Sheikh, Noorann, Shelley, Benjamin, Shelton, Sarah, Shenoy, Anil, Shenton, Julie, Shephardson, Sarah, Shepherd, Amy, Shepherd, Kate, Shepherd, Lorna, Shepherd, Scott, Sheppard, Gareth, Sheppeard, Rhian, Sheridan, Helen, Sheridan, Ray, Sherridan, Samuel, Sherris, Leanne, Sherwin, Susanna, Shibly, Shaad, Shiham, Fathimath F, Shilladay, Cassandra, Shillitoe, Ben, Shingadia, Delane, Shioi, Chiaki, Shirgaonkar, Anand, Shirley, Kim, Shirt, Helen, Shonubi, Adebusola, Shoote, Jane, Shorrocks, Ruth, Shortman, Rob, Shotton, Rohan, Shotton, Sarah, Shovelton, Charmaine, Shpuza, Ervin, Shrestha, Anil, Shrestha, Apurba, Shrestha, Nora, Shrestha, Suchita, Shuker, Karen, Shurlock, Jonathan, Shurmer, Jack, Shuvo, Erfanur R, Siame, Gilbert, Siamia, Loria, Siddavaram, Seshnag, Siddique, Nasir, Siddique, Shahla, Siddique, Sohail, Siddle, Elaine, Sidebotham, Emma, Sidebottom, Jo, Sievers, Roy, Siggens, Katie, Sikondari, Nyma, Silva, Sofia V, Silva Moniz, Claudia, Sim, Malcolm, Simangan, Theresa, Simbi, Vimbai, Sime, Robert, Simmons, George, Simmons, Oliver, Simms, Richard, Simon, Laura, Simon, Merritt, Simon, Natalie, Simpkins, Samantha, Simpson, Angela, Simpson, Anna, Simpson, Danny, Simpson, Georgina, Simpson, Joanne, Simpson, Kerry, Simpson, Maria, Simpson, Phillip, Simpson, Thomas, Simpson, Kathryn, Sinclair, Simon, Sing, Cindy, Singh, Ankita, Singh, Claire, Singh, Davinder, Singh, Jayaprakash, Singh, Jyoti, Singh, Lokeshwar, Singh, Manjeet, Singh, Nadira, Singh, Pankaj, Singh, Prabhsimran, Singh, Salil, Singh, Saurabh, Singhal, Parag, Singizi, Bryan, Singler, Vicky, Sinha, Manas, 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Jacky, Smith, Jessica, Smith, Kate, Smith, Kerry, Smith, Lara, Smith, Linda, Smith, Lisa, Smith, Loren, Smith, Maria, Smith, Mark, Smith, Martha A, Smith, Mel, Smith, Nicholas, Smith, Oliver, Smith, Philippa, Smith, Rachel, Smith, Rebecca, Smith, Rheanna, Smith, Richard, Smith, Sally, Smith, Samantha, Smith, Stacey, Smith, Stephanie, Smith, Susan, Smith, Tracy, Smith, Victoria, Smith, Imogen, Smith, John, Smolen, Sue, Smuts, Sara, Smyth, Jennifer, Smyth, Naoise, Snell, Annette, Snell, David, Snell, Luke, So, Alfred, So, Beng, Soan, Michelle, Sobande, Toluleyi, Sobowiec Kouman, Sonia, Sobrino Diaz, Alberto, Sohail, Basit, Sohail, Bina, Sohal, Herminder, Soiza, Roy, Solademi, Olajumoke, Soleimani, Babak, Solesbury, Amanda, Soliman, Mohamed, Solis, Bernadette, Solly, Reanne, Solomon, Louise, Somalanka, Subash, Somashekar, Chandrashekaraiah, Sommerfield, Sven, Soni, Govind, Sonia, Raj, Sonoiki, Temi, Soo, Shiu-Ching, Soor, Pavandeep, Soothill, Germander, Soren, Jennifer, Sothinathan, Apina, Sothirajah, Pragalathan, Sousa, Jessica, Soussi, Najwa, Southam, Donna, Southern, David, Southern, Iain, Southern, Louise, Southin, Sara M, Southwell, Jessica, Southworth, Thomas, Sowden, Sandra, Sowter, Jason, Spalding, Claudia, Spata, Enti, Speare, Catherine, Spears, Katie, Spears, Mark, Speirs, Lynne, Speirs, Susan, Spence, Michelle, Spence, Niamh, Spencer, Branwell, Spencer, Gisele, Spencer, Rebecca, Spencer, Sue, Spencer, Tom, Spickett, Helen, Spillane, Jennifer, Spiller, William, Spinks, Kerry, Spinks, Michelle, Spittle, Nick, Spray, Sarah, Spriggs, Janet, Spring, Oliver, Squires, Gemma, Squires, Jack, Squires, Rebecca, Sreenivasan, Ram, Sreenivasan, Shiva, Sri Paranthamen, K, Srikantaiah, Rajesh, Srinivasan, Koottalai, Srinivasan, Ramesh, Srirajamadhuveeti, Asha, Srirathan, Vino, Stacey, Rhodri, Stacpoole, Sybil, Stadon, Louise, Stagg, William J, Staines, Jocasta, Staines, Nikki, Stammers, Katie, Stanciu, Roxana, Stanczuk, Grazyna, Standley, Thomas, Staniforth, Brittany, Stanton, Andrew, Stanton, Lisa, Staples, Robyn, Stapley, Simon, Staplin, Natalie, Stark, Adam, Starkey, Elizabeth, Starnes, David S, Starr, Michelle, Stead, Rachel, Stebbing, Clare, Steele, Conor, Steer, Henry, Steer, John, Stefania, Vergnano, Stefanowska, Paula, Steffensen, Femke, Stemp, Caroline, Stenson, Emma, Stephens, Alison, Stephensen, David, Stephenson, Elaine, Sterrenburg, Monique, Stevens, Jennifer, Stevens, Melanie, Stevens, Will, Stevenson, Amy, Stevenson, Andrew, Stevenson, Lesley, Stevenson, Sarah, Steward, Matthew, Stewart, Christopher, Stewart, Claire, Stewart, Colin, Stewart, Dobree A, Stewart, Katelyn, Stewart, Keely, Stewart, Kristina, Stewart, McKenna, Stewart, Melissa, Stewart, Rachel, Stewart, Richard, Stickley, Jo, Stiller, Gemma, Stirrup, Sarah, Stock, Sarah, Stockdale, Alexander, Stocker, Danielle, Stockham, Lynne, Stockton, Paul, Stoddard, Emma, Stokes, Chelsea, Stokes, Chris, Stone, Ben, Stone, Roisin, Stone, Sarah, Stoner, Emma-Jane, Storey, Imogen, Storton, 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Tereszkowski-Kaminski, Radoslaw, Terrett, Lynne, Terry, Louise, Tesha, Tesha I M, Tetla, Dariusz, Tewari, Shirish, Tewkesbury, Daniel, Texeira, Joana, Tey, ChiaLing, Thake, Miriam, Thakker, Clare, Thakker, Manish, Thakrar, Jayna, Thamu, Bhavneet, Thatcher, Hilary, Thayanandan, Andrew, Thazhatheyil, Krishna, Thein, Eaint, Theocharidou, Lambrini, Thet, Phyu, Thevarajah, Kapeendran, Thevendra, Mayooran, Thiri Phoo, Nang, Thirlwall, Yvette, Thirumaran, Muthu, Thomas, Alice, Thomas, Andrew, Thomas, Caradog, Thomas, Emma, Thomas, Enson, Thomas, Esther, Thomas, Helen, Thomas, James, Thomas, Jordan L, Thomas, Karen, Thomas, Koshy, Thomas, Lucy, Thomas, Rachel, Thomas, Rebecca, Thomas, Rhys, Thomas, Ruth, Thomas, Sarah, Thomas, Sherine, Thomas, Tessy, Thomas, Vicky, Thomasson, Kirsty, Thomas-Turner, Rhian, Thompson, Catherine, Thompson, Christopher, Thompson, Clara, Thompson, Emma, Thompson, Fiona, Thompson, Hilary, Thompson, Jessica, Thompson, Katharine, Thompson, Laura, Thompson, Liz, 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Georgios, Tso, Simon, Tucker, Natasha, Tucker, Sally, Tucker, Stephanie, Tudor, Daisy E, Tufail, Aisha, Tuff, Jess, Tuffney, Jemma, Tully, Redmond, Tunesi, Grace, Turbitt, Killiam, Turel, Rezon, Turgut, Tolga, Turley, Claudia, Turnbull, Alison, Turner, Aine, Turner, Ash, Turner, Charlotte, Turner, Gail, Turner, Georgina, Turner, Kate, Turner, Kelly, Turner, Kim, Turner, Lucy, Turner, Lynne C, Turner, Mark, Turner, Patricia, Turner, Sally, Turner, Samantha, Turner, Sarah, Turner, Victoria, Turner-bone, Ian, Turney, Sharon, Turvey, Jon, Tweed, Conor, Tweed, David, Twemlow, Rebecca, Twohey, Emma, Tyagi, Bhavya, Tyagi, Vedang, Tyer, Abigail, Tyler, Amanda, Tyler, Jayne, Tyler, Jennifer, Tyzack, Alison, Tzavaras, Petros, Tzinieris, Ioannis, Uddin, A Wahid, Uddin, Mohammad S, Uddin, Ruhama, Uddin, Ruzena, Ugoji, Jacinta, Ukaegbu, Edith N, Ul Hassan, Waqar, Ul-Haq, Zia, Ullah, Salamat, Ullah, Sana, Ullah, Sanda, Um, Ju, Umaipalan, Athavan, Umate, Anil, Umeadi, Judith, Umeh, Akudo, Umeojiako, Wilfred, Ummat, Ben, Underhill, Emma, Underwood, Charlotte, Underwood, Jonathan, Unsworth, Adam, Uppal, Veerpal S, Upson, Gerry, Ur Rasool, Masood, Uriel, Alison, Urruela, Sebastian, Uru, Hiromi, Usher, Jess, Usher, Miranda, Usher, Rebecca, Usher-Rea, Alexandra, Ustianowski, Andrew, Uzu, Hiromi, Vaccari, Linda C, Vaghela, Uddhav, Vaidya, Abhay, Vail, Denny, Valecka, Bernardas, Valentine, Jennifer, Valeria, Balan, Vallabhaneni, Pramodh, Vallotton, Nick, Vamplew, Luke, Vamvakiti, Ekaterini, Vamvakopoulos, Joannis, van Bruggen, Lucia, van de Venne, Maud, van der Meer, Alex, van der Stelt, Nora, van Koutrik, Lynne, Van Loggerenberg, Alexander, Vance-Daniel, Joseph, Vancheeswaran, Rama, Vandeyoon, Samuel I, Vankayalapati, Padma, Vanmali, Piyush, Vansomeren, Chloe, Van't Hoff, William, Vara, Sejal, Vardy, Stehen J, Varghese, Anu, Varghese, Maria, Varney, William, Varnier, Giulia, Varouxaki, Anna-Nektaria, Varquez, Resti, Vasadi, Valeria, Vass, Olivia, Vassell, Katherine, Vasu, Vimal, 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Williams, Patricia, Williams, Penny, Williams, Rachel, Williams, Robin, Williams, Rupert, Williams, Samson, Williams, Sarah, Williams, Sophie, Williams, Steffan, Williams, Tamanna, Williams, Tania, Williamson, Annie, Williamson, Cath, Williamson, Catherine, Williamson, Dawn, Williamson, James D, Williamson, Jodie, Williamson, Rachel, Williamson, Cath, Williamson, Helen, Willis, Elaine, Willis, Elizabeth, Willis, Emily, Willis, Heather, Willis, Herika, Willis, Joanna, Wills, Louise, Willsher, Lucy, Willshire, Catherine, Willson, Francesca, Willson, Jayne, Wilson, Alison, Wilson, Andrea, Wilson, Anna, Wilson, Antoinette, Wilson, Billy, Wilson, David, Wilson, Imogen, Wilson, James, Wilson, Karen, Wilson, Kate, Wilson, Kristy-Ann, Wilson, Lucinda, Wilson, Mark, Wilson, Stephen, Wilson, Toni, Wilson, John, Win, Khin Lei Yee, Win, Marlar, Win, Than, Win, Tin Tin, Win, Wut Yee Win, Winckworth, Lucinda, Winder, Laura, Winder, Piers, Winearl, Stuart, Winmill, Helen, Winn, Simon, Winpenny, 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Woods, Charlotte, Woods, Jane, Woods, Katherine, Woods, Sarah, Woodward, Zoe, Woolcock, Megan, Wooldridge, Gemma, Woolf, Rebecca, Woollard, Chris, Woollard, Christopher, Woollen, Louisa, Woolley, Emma, Woolley, Jade, Woosey, Daniel, Wootton, Dan, Wootton, Joanne, Worley, Daniel, Worton, Stephy, Wraight, Jonathan, Wray, Maria, Wren, Kim, Wren, Lynn, Wrey Brown, Caroline, Wright, Catherine, Wright, Demi, Wright, Francesca, Wright, Holly, Wright, Imogen, Wright, Lianne, Wright, Rachel, Wright, Sarah, Wright, Stephanie, Wright, Tim, Wroe, Caroline, Wroe, Hannah, Wu, Henry, Wu, Peishan, Wu, Pensee, Wubetu, Jonathan, Wulandari, Fitria, Wulandari, Retno, Wurie, Subie, Wyatt, Craig, Wyn-Griffiths, Frederick, Wynter, Inez, Xavier, Bindhu, Xhikola, Arnold, Xia, Bingru E, Xia, Zhongyang, Yacoba, Effua, Yakubi, Masseh, Yan, May, Yanagisawa, Yuuki, Yang, Freda, Yang, Yingjia, Yanney, Michael, Yap, Woei Lin, Yaqoob, Nabil, Yasmin, Salima, Yates, Bryan, Yates, David, Yates, Edward, Yates, Helen, Yates, Thomas, Yates, Mark, Ye, Jessica, Yearwood Martin, Charlotte, Yein, Khin, Yelnoorkar, Fiona, Yeoh, Alastair, Yeung, Chun Yu, Yew, Peter, Yewatkar, Durgesh, Ylquimiche Melly, Laura B, Ynter, Inez, Yong, H, Yorke, Jemma, Youens, Jasmine, Younes Ibrahim, Abdel, Young, Eoin, Young, Gail, Young, Louise, Yousafzar, Asfand, Youssouf, Sajeda, Yousuf, Ahmed, Yu, Chrissie, Yuan, Jack S J, Yufaniaputri, Nindya, Yung, Bernard, Yusef, Daniel, Yusef, Said, Yusuf, Intekhab, Zafar, Anna-Sophia, Zagalo, Silvia, Zaher, Su, Zahoor, Aqsa, Zainab, Mahrukh, Zak, Thornton, Zaki, Kareem, Zakir, Nabhan, Zalewska, Kasia, Zamalloa, Ane, Zaman, Mohsin, Zaman, Shakir, Zamikula, Julie, Zammit, Louise, Zammit-Mangion, Marie, Zawadzka, Marcelina, Zayed, Mohammed, Zebracki, Esther, Zehnder, Daniel, Zeidan, Lisa, Zeinali, Darius, Zhang, Jing, Zhao, Xiaobei, Zheng, Dongling, Zhu, Doreen, Zia, Madiha, Zibdeh, Omar, Zill-E-Huma, Rabia, Zin, Ei Thankt, Zincone, Eva, Zindoga, Garikai, Zinkin, Eleanor, Zinyemba, Vivian, Zipitis, Christos, Zitter, Letizia, Zmierczak, Arkadiusz, Zubikarai, Garazi, Zubir, Azam, Zuhra, Naz, Zulaikha, Rasha, Zulfikar, Sabrina, Zullo, Carol, and Zuriaga-Alvaro, Ana
- The Lancet; July-August 2022, Vol. 400 Issue: 10349 p359-368, 10p
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We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor, for the treatment of patients admitted to hospital with COVID-19.
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53. Levels of Parental Drinking in the Presence of Children: An Exploration of Attitudinal Correlates. [2022]
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Bowden JA, Delfabbro P, Room R, Miller CL, and Wilson C
Alcohol and alcoholism (Oxford, Oxfordshire) [Alcohol Alcohol] 2022 Jul 09; Vol. 57 (4), pp. 460-469.
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Adult, Australia epidemiology, Child, Cross-Sectional Studies, Female, Humans, Parents, Alcohol Drinking epidemiology, and Alcoholic Intoxication
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Aims: This study aimed to examine perceived social norms, the effect of parental drinking on these norms, alcohol use in front of children, and how norms and consumption vary based on child age and gender of the parent.
Methods: A cross-sectional online panel survey was undertaken with n = 1000 Australian adults (including 670 parents) aged 18-59 years. The survey assessed: alcohol consumption in front of children; normative attitudes towards drinking in the presence of children; and perceived social norms.
Results: Overall, 33.9% of parents reported drinking a glass of alcohol each day or a couple of times a week, 18.2% reported getting slightly drunk and 7.8% indicated getting visibly drunk each day or a couple of times a week with their children present. In total, 37.5% reported drinking in front of their children at least weekly. Fathers were more likely to drink in front of children than mothers. Most parents deemed drinking small amounts of alcohol in front of children as acceptable but did not accept drunkenness. Respondents were less concerned about a father drinking one or two drinks in front of their children than a mother. Social expectations were not related to child age, but norms related to others' perceived behaviour were.
Conclusions: Many parents, particularly fathers consume alcohol in front of their children. There is a need to target health promotion strategies to adults and parents consuming in excess of health guidelines, and to the many parents who are consuming alcohol at higher levels in front of their children.
(© The Author(s) 2021. Medical Council on Alcohol and Oxford University Press.)
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Mitchell J, Alejo JL, Chiang TPY, Kim J, Chang A, Abedon AT, Avery RK, Tobian AAR, Massie AB, Levan ML, Warren DS, Garonzik-Wang JM, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 Jul 01; Vol. 106 (7), pp. e338-e340. Date of Electronic Publication: 2022 Apr 15.
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Antibodies, Viral, Antibody Formation, COVID-19 Vaccines, Humans, SARS-CoV-2, Transplant Recipients, COVID-19 prevention control, and Organ Transplantation adverse effects
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Competing Interests: D.L.S. has the following financial disclosures: consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, Thermo Fisher Scientific, Regeneron, and AstraZeneca. R.K.A. has study/grant support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, Regeneron, Takeda/Shire, and Vir/GSK and is an Associate Reviewer for Transplantation. M.L.L. is the Social Media Editor for Transplantation. The other authors declare no conflicts of interest.
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Baliga S, Gallotto S, Bajaj B, Lewy J, Weyman E, Lawell MP, Yeap BY, Ebb DE, Huang M, Caruso P, Perry A, Jones RM, MacDonald SM, Tarbell NJ, and Yock TI
Neuro-oncology [Neuro Oncol] 2022 Jun 01; Vol. 24 (6), pp. 1010-1019.
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Brain Stem, Child, Cohort Studies, Humans, Protons, Young Adult, Cerebellar Neoplasms drug therapy, and Medulloblastoma drug therapy
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Background: Survivors of pediatric medulloblastoma experience long-term morbidity associated with the toxic effects of postoperative radiotherapy (RT). Proton RT limits radiation dose to normal tissues thereby reducing side effects of treatment while maintaining high cure rates. However, long-term data on disease outcomes and long-term effects of proton RT remain limited.
Methods: One hundred seventy-eight pediatric medulloblastoma patients treated with proton RT between 2002 and 2016 at the Massachusetts General Hospital comprise the cohort of patients who were treated with surgery, radiation therapy, and chemotherapy. We evaluated event-free survival (EFS), overall survival (OS), and local control using the Kaplan-Meier method. The cumulative incidence of brainstem injury and secondary malignancies was assessed.
Results: Median follow-up was 9.3 years. One hundred fifty-nine patients (89.3%) underwent a gross total resection (GTR). The 10-year OS for the entire cohort, standard-risk (SR), and intermediate/high-risk (IR/HR) patients was 79.3%, 86.9%, and 68.9%, respectively. The 10-year EFS for the entire cohort, SR, and IR/HR cohorts was 73.8%, 79.5%, and 66.2%. The 10-year EFS and OS for patients with GTR/NTR were 75.3% and 81.0% vs 57.7% and 61.0% for subtotal resection (STR). On univariate analysis, IR/HR status was associated with inferior EFS, while both anaplastic histology and IR/HR status were associated with worse OS. The 10-year cumulative incidence of secondary tumors and brainstem injury was 5.6% and 2.1%, respectively.
Conclusions: In this cohort study of pediatric medulloblastoma, proton RT was effective, and disease outcomes were comparable to historically treated photon cohorts. The incidence of secondary malignancies and brainstem injury was low in this cohort with mature follow-up.
(© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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Raafs AG, Vos JL, Henkens MTHM, Slurink BO, Verdonschot JAJ, Bossers D, Roes K, Gerretsen S, Knackstedt C, Hazebroek MR, Nijveldt R, and Heymans SRB
JACC. Cardiovascular imaging [JACC Cardiovasc Imaging] 2022 Jun; Vol. 15 (6), pp. 1015-1026. Date of Electronic Publication: 2022 May 11.
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Contrast Media, Female, Gadolinium, Heart Atria, Humans, Magnetic Resonance Imaging, Cine, Male, Middle Aged, Predictive Value of Tests, Prognosis, Stroke Volume, Ventricular Function, Left, Cardiomyopathy, Dilated, and Ventricular Dysfunction, Left
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Background: The left atrium is an early sensor of left ventricular (LV) dysfunction. Still, the prognostic value of left atrial (LA) function (strain) on cardiac magnetic resonance (CMR) in dilated cardiomyopathy (DCM) remains unknown.
Objectives: The goal of this study was to evaluate the prognostic value of CMR-derived LA strain in DCM.
Methods: Patients with DCM from the Maastricht Cardiomyopathy Registry with available CMR imaging were included. The primary endpoint was the combination of sudden or cardiac death, heart failure (HF) hospitalization, or life-threatening arrhythmias. Given the nonlinearity of continuous variables, cubic spline analysis was performed to dichotomize.
Results: A total of 488 patients with DCM were included (median age: 54 [IQR: 46-62] years; 61% male). Seventy patients (14%) reached the primary endpoint (median follow-up: 6 [IQR: 4-9] years). Age, New York Heart Association (NYHA) functional class >II, presence of late gadolinium enhancement (LGE), LV ejection fraction (LVEF), LA volume index (LAVI), LV global longitudinal strain (GLS), and LA reservoir and conduit strain were univariably associated with the outcome (all P < 0.02). LA conduit strain was a stronger predictor of outcome compared with reservoir strain. LA conduit strain, NYHA functional class >II, and LGE remained associated in the multivariable model (LA conduit strain HR: 3.65 [95% CI: 2.01-6.64; P < 0.001]; NYHA functional class >II HR: 1.81 [95% CI: 1.05-3.12; P = 0.033]; and LGE HR: 2.33 [95% CI: 1.42-3.85; P < 0.001]), whereas age, N-terminal pro-B-type natriuretic peptide, LVEF, left atrial ejection fraction, LAVI, and LV GLS were not. Adding LA conduit strain to other independent predictors (NYHA functional class and LGE) significantly improved the calibration, accuracy, and reclassification of the prediction model (P < 0.05).
Conclusions: LA conduit strain on CMR is a strong independent prognostic predictor in DCM, superior to LV GLS, LVEF, and LAVI and incremental to LGE. Including LA conduit strain in DCM patient management should be considered to improve risk stratification.
Competing Interests: Funding Support and Author Disclosures This study was supported by the Netherlands Cardiovascular Research Initiative, an initiative with support of the Dutch Heart Foundation, CVON She-PREDICTS, grant 2017-21, CVON-DCVA Double Dosis 2021. Dr Heymans has provided current and previous scientific advice to AstraZeneca, CellProthera, Novo Nordisk, Bayer, Pfizer, CSL Behring, and Merck on heart failure and cardiomyopathies. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
(Copyright © 2022 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
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Ssenyonga, Naomi, Stiller, Charles, Nakata, Kayo, Shalkow, Jaime, Redmond, Shelagh, Bulliard, Jean-Luc, Girardi, Fabio, Fowler, Christine, Marcos-Gragera, Rafael, Bonaventure, Audrey, Saint-Jacques, Nathalie, Minicozzi, Pamela, De, Prithwish, Rodríguez-Barranco, Miguel, Larønningen, Siri, Di Carlo, Veronica, Mägi, Margit, Valkov, Mikhail, Seppä, Karri, Wyn Huws, Dyfed, Coleman, Michel P, Allemani, Claudia, Bouzbid, Sabiha, Hamdi-Chérif, Mokhtar, Kara, Lamia, Meguenni, Kaouel, Regagba, Derbali, Bayo, Sine, Cheick Bougadari, Traore, Manraj, Shyam Shunker, Bendahhou, Karima, Ladipo, Akinade, Ogunbiyi, Olufemi, Somdyala, Nontuthuzelo, Chaplin, María Agustina, Moreno, Florencia, Calabrano, Gladis, Espinola, Silvia, Carballo Quintero, Beatriz, Fita, Rosalba, Laspada, Walter, Ibañez, Susana, Lima, Carlos, Mafra Da Costa, Allini, De Souza, Paulo César, Chaves, Juliana, Laporte, Cyntia, Curado, Maria Paula, de Oliveira, Jose Carlos, Veneziano, Claudia, Veneziano, Donaldo, Almeida, Ana Beatriz, Latorre, Maria, Azevedo e Silva, Gulnar, Rebelo, Marise, Santos, Marceli, Galaz, Juan, Aparicio Aravena, Mackarena, Sanhueza Monsalve, Jocelyn, Herrmann, Denise, Vargas, Solange, Herrera, Victor, Uribe, Claudia, Bravo, Luis Eduardo, Garcia, Luz Stella, Arias-Ortiz, Nelson, Morantes, Daniela, Jurado, Daniel, Yépez Chamorro, María, Delgado, Sandra, Ramirez, Melissa, Galán Alvarez, Yaima, Torres, Priscila, Martínez-Reyes, Fray, Jaramillo, Leyda, Quinto, Rina, Castillo, Jhoanna, Mendoza, Mariela, Cueva, Patricia, Yépez, José, Bhakkan, Bernard, Deloumeaux, Jacqueline, Joachim, Clarisse, Macni, Jonathan, Carrillo, Rodolfo, Shalkow Klincovstein, Jaime, Rivera Gomez, Rebeca, Perez, Patricia, Poquioma, Ebert, Tortolero-Luna, Guillermo, Zavala, Diego, Alonso, Rafael, Barrios, Enrique, Eckstrand, Angela, Nikiforuk, Cindy, Woods, Ryan, Noonan, Gail, Turner, Donna, Kumar, Eshwar, Zhang, Bin, Dowden, Jeff, Doyle, Gregory, Saint-Jacques, Nathalie, Walsh, Gordon, Anam, Aniq, De, Prithwish, McClure, Carol, Vriends, Kim, Bertrand, Christine, Ramanakumar, Agnihotram, Kozie, Serena, Stuart-Panko, Heather, Freeman, Tara, George, Justin, Avila, Rosa, O'Brien, David, Holt, Abby, Almon, Lyn, Ward, Kevin, Kwong, Sandy, Morris, Cyllene, Rycroft, Randi, Mueller, Lloyd, Phillips, Cathryn, Brown, Heather, Cromartie, Betsy, Ruterbusch, Julie, Schwartz, Ann, Levin, Gary, Wohler, Brad, Bayakly, Rana, Gomez, Scarlett, McKinley, Meg, Cress, Rosemary, Davis, Joni, Hernandez, Brenda, Johnson, Christopher, Morawski, Bozena, Ruppert, Laura, Bentler, Suzanne, Charlton, Mary, Huang, Bin, Tucker, Thomas, Deapen, Dennis, Liu, Lihua, Hsieh, Mei-Chin, Wu, Xiao-Cheng, Schwenn, Molly, Stern, Kimberly, Gershman, Susan, Knowlton, Richard, Alverson, Georgetta, Weaver, Tamara, Desai, Jay, Rogers, Deirdre, Jackson-Thompson, Jeanette, Lemons, Debbi, Zimmerman, Heather, Hood, Michelle, Roberts-Johnson, Jenifer, Hammond, Whitney, Rees, Judith, Pawlish, Karen, Stroup, Antoinette, Key, Charles, Wiggins, Charles, Kahn, Amy, Schymura, Maria, Radhakrishnan, Soundarya, Rao, Chandrika, Giljahn, Lynn, Slocumb, Roberta, Dabbs, Christy, Espinoza, Raffaella, Aird, Karen, Beran, Todd, Rubertone, Jim, Slack, Stephen, Oh, Junhie, Janes, Tiffany, Schwartz, Stephen, Chiodini, Stephanie, Hurley, Deborah, Whiteside, Martin, Rai, Saroj, Williams, Melanie, Herget, Kim, Sweeney, Carol, Johnson, Alison, Keitheri Cheteri, Mahesh, Migliore Santiago, Patti, Blankenship, Steven, Farley, Shawn, Borchers, Robert, Malicki, Robin, Espinoza, Julia, Grandpre, Joseph, Edwards, Brenda, Mariotto, Angela, Weir, Hannah, Wilson, Reda, Wang, Ning, Yang, Lei, Chen, Jian-Shun, He, Yu-Tong, Song, Guo-Hui, Gu, Xiao-Ping, Mei, Dan, Ge, Heng-Ming, Wu, Tong-Hao, Li, Yan-Yan, Zhao, De-Li, Jin, Feng, Zhang, Jian-Hua, Zhu, Feng-Dong, Junhua, Qian, Yang, Yan Lei, Jiang, Chun-Xiao, Biao, Wang, Wang, Jian, Li, Qi-Long, Yi, He, Zhou, Xin, Dong, JianMei, Li, WeiWei, Fu, Fang-Xian, Chen, Jian-Guo, Zhu, Jian, Li, Yan-Hua, Lu, Yu-Qiang, Fan, Min, Huang, Su-Qin, Guo, Guo-Ping, Zhaolai, Hua, Wei, Kuangrong, Chen, Wan-Qing, Wei, Wenqiang, Zeng, Hongmei, Demetriou, Anna, Mang, Wai Kong, Ngan, Kai Cheong, Kataki, Amal, Krishnatreya, Manigreeva, Jayalekshmi, Padmavathi Amma, Sebastian, Paul, George, Preethi, Mathew, Aleyamma, Nandakumar, Ambakumar, Malekzadeh, Reza, Roshandel, Gholamreza, Keinan-Boker, Lital, Silverman, Barbara, Ito, Hidemi, Koyanagi, Yuriko, Sato, Masako, Tobori, Fumio, Nakata, Ichiro, Teramoto, Norihiro, Hattori, Masakazu, Kaizaki, Yasuharu, Moki, Fumitaka, Sugiyama, Hiromi, Utada, Mai, Nishimura, Makiko, Yoshida, Keiichi, Kurosawa, Katsuki, Nemoto, Yuji, Narimatsu, Hiroto, Sakaguchi, Masahiko, Kanemura, Seiki, Naito, Michiko, Narisawa, Rintaro, Miyashiro, Isao, Nakata, Kayo, Mori, Daisuke, Yoshitake, Mayuko, Oki, Izumi, Fukushima, Norimasa, Shibata, Akiko, Iwasa, Keiichiro, Ono, Chie, Matsuda, Tomohiro, Nimri, Omar, Jung, Kyu-Won, Won, Young-Joo, Alawadhi, Eiman, Elbasmi, Amani, Ab Manan, Azizah, Adam, Farzaana, Nansalmaa, Erdenekhuu, Tudev, Undarmaa, Ochir, Chimedsuren, Al Khater, Al Hareth, El Mistiri, Mufid, Lim, Gek Hsiang, Teo, Yik Ying, Chiang, Chun-Ju, Lee, Wen-Chung, Buasom, Rangsiya, Sangrajrang, Suleeporn, Suwanrungruang, Krittika, Vatanasapt, Patravoot, Daoprasert, Karnchana, Pongnikorn, Donsuk, Leklob, Atit, Sangkitipaiboon, Somphob, Geater, Sarayut, Sriplung, Hutcha, Ceylan, Okan, Kög, Iskender, Dirican, Oya, Köse, Tülay, Gurbuz, Tulın, Karašahin, Füsun Emine, Turhan, Duygu, Aktaş, Umut, Halat, Yakup, Eser, Sultan, Yakut, Cankut, Altinisik, Merve, Cavusoglu, Yasar, Türkköylü, Ayşe, Üçüncü, Nuršen, Hackl, Monika, Zborovskaya, Anna, Aleinikova, Olga, Henau, Kris, Van Eycken, Liesbet, Atanasov, Trayan, Valerianova, Zdravka, Šekerija, Mario, Dušek, Ladislav, Zvolský, Miroslav, Steinrud Mørch, Lina, Storm, Hans, Wessel Skovlund, Charlotte, Innos, Kaire, Mägi, Margit, Malila, Nea, Seppä, Karri, Jégu, Jérémie, Velten, Michel, Cornet, Edouard, Troussard, Xavier, Bouvier, Anne-Marie, Guizard, Anne-Valérie, Bouvier, Véronique, Launoy, Guy, Dabakuyo Yonli, Sandrine, Poillot, Marie-Laure, Maynadié, Marc, Mounier, Morgane, Vaconnet, Lina, Woronoff, Anne-Sophie, Daoulas, Mélanie, Robaszkiewicz, Michel, Clavel, Jacqueline, Poulalhon, Claire, Desandes, Emmanuel, Lacour, Brigitte, Baldi, Isabelle, Pouchieu, Camille, Amadeo, Brice, Coureau, Gaëlle, Monnereau, Alain, Audoin, Magali, D'Almeida, Tania, Boyer, Séverine, Hammas, Karima, Trétarre, Brigitte, Colonna, Marc, Delafosse, Patricia, Plouvier, Sandrine, Cowppli-Bony, Anne, Molinié, Florence, Bara, Simona, Ganry, Olivier, Lapôtre-Ledoux, Bénédicte, Daubisse-Marliac, Laetitia, Bossard, Nadine, Estève, Jacques, Uhry, Zoé, Stabenow, Roland, Wilsdorf-Köhler, Heide, Eberle, Andrea, Luttmann, Sabine, Löhden, Imma, Nennecke, Alice, Kieschke, Joachim, Sirri, Eunice, Justenhoven, Christina, Zeissig, Sylke, Holleczek, Bernd, Eisemann, Nora, Katalinic, Alexander, Asquez, Rachelle, Kumar, Vijay, Petridou, Eleni, Ólafsdóttir, Elínborg, Tryggvadóttir, Laufey, Murray, Deirdre, Walsh, Paul, Sundseth, Hildrun, Mazzoleni, Guido, Vittadello, Fabio, Coviello, Enzo, Cuccaro, Francesco, Galasso, Rocco, Sampietro, Giuseppe, Magoni, Michele, Ardizzone, Antonino, D'Argenzio, Angelo, Di Prima, Alessia Anna, Ippolito, Antonella, Lavecchia, Anna Maria, Sutera Sardo, Antonella, Gola, Gemma, Ballotari, Paola, Giacomazzi, Erica, Ferretti, Stefano, Dal Maso, Luigino, Serraino, Diego, Celesia, Maria Vittoria, Filiberti, Rosa Angela, Pannozzo, Fabio, Melcarne, Anna, Quarta, Fabrizio, Andreano, Anita, Russo, Antonio Giampiero, Carrozzi, Giuliano, Cirilli, Claudia, Cavalieri d'Oro, Luca, Rognoni, Magda, Fusco, Mario, Vitale, Maria Francesca, Usala, Mario, Cusimano, Rosanna, Mazzucco, Walter, Michiara, Maria, Sgargi, Paolo, Boschetti, Lorenza, Chiaranda, Giorgio, Seghini, Pietro, Maule, Milena, Merletti, Franco, Spata, Eugenia, Tumino, Rosario, Mancuso, Pamela, Vicentini, Massimo, Cassetti, Tiziana, Sassatelli, Romano, Falcini, Fabio, Giorgetti, Stefania, Caiazzo, Anna Luisa, Cavallo, Rossella, Piras, Daniela, Bella, Francesca, Madeddu, Anselmo, Fanetti, Anna Clara, Maspero, Sergio, Carone, Simona, Mincuzzi, Antonia, Candela, Giuseppa, Scuderi, Tiziana, Gentilini, Maria Adalgisa, Rizzello, Roberto, Rosso, Stefano, Zanetti, Roberto, Caldarella, Adele, Intrieri, Teresa, Bianconi, Fortunato, Stracci, Fabrizio, Contiero, Paolo, Tagliabue, Giovanna, Rugge, Massimo, Zorzi, Manuel, Beggiato, Simonetta, Brustolin, Angelita, De Angelis, Roberta, Gatta, Gemma, Maurina, Anita, Oniščuka, Marija, Mousavi, Mohsen, Lipunova, Nadezda, Vincerzevskienė, Ieva, Agius, Dominic, Calleja, Neville, Siesling, Sabine, Visser, Otto, Johannesen, Tom, Larønningen, Siri, Trojanowski, Maciej, Mierzwa, Tomasz, Rachtan, Jadwiga, Kępska, Kamila, Kościańska, Beata, Wójcik-Tomaszewska, Joanna, Motnyk, Marcin, Gos, Anna, Bielska-Lasota, Magdalena, Didkowska, Joanna, Wojciechowska, Urszula, Forjaz de Lacerda, Gonçalo, Rego, Raul, Carrito, Branca, Pais, Ana, Bento, Maria José, Rodrigues, Jessica, Lourenço, Antonio, Mayer-da-Silva, Alexandra, Blaga, Luminita, Coza, Daniela, Valkov, Mikhail, Gusenkova, Lubov, Lazarevich, Olga, Prudnikova, Olga, Vjushkov, Dmitri Mikhailovich, Egorova, Alla, Orlov, Andrey, Pikalova, Lidiya, Zhuikova, Lilia, Adamcik, Juraj, Safaei Diba, Chakameh, Zadnik, Vesna, Zagar, Tina, De-La-Cruz, Marta, Lopez-de-Munain, Arantza, Aleman, Araceli, Rojas, Dolores, Chillarón, Rosario Jiménez, Navarro, Ana Isabel Marcos, Marcos-Gragera, Rafael, Puigdemont, Montse, Rodríguez-Barranco, Miguel, Sánchez Perez, María-José, Franch Sureda, Paula, Ramos Montserrat, Maria, Chirlaque López, Maria Dolores, Sánchez Gil, Antonia, Ardanaz, Eva, Guevara, Marcela, Cañete-Nieto, Adela, Peris-Bonet, Rafael, Carulla, Marià, Galceran, Jaume, Almela, Fernando, Sabater, Consol, Khan, Staffan, Pettersson, David, Dickman, Paul, Staehelin, Katharina, Struchen, Benjamin, Herrmann, Christian, Mousavi, Seyed Mohsen, Egger Hayoz, Céline, Bouchardy, Christine, Schaffar, Robin, Went, Philip, Bulliard, Jean-Luc, Maspoli-Conconi, Manuela, Kuehni, Claudia, Redmond, Shelagh, Bordoni, Andrea, Ortelli, Laura, Chiolero, Arnaud, Konzelmann, Isabelle, Rohrmann, Sabine, Wanner, Miriam, Broggio, John, Rashbass, Jem, Stiller, Charles, Fitzpatrick, Deirdre, Gavin, Anna, Morrison, David, Thomson, Catherine, Greene, Giles, Huws, Dyfed, Allemani, Claudia, Coleman, Michel, Di Carlo, Veronica, Girardi, Fabio, Matz, Melissa, Minicozzi, Pamela, Sanz, Natalia, Ssenyonga, Naomi, Stephens, Richard, Chalker, Elizabeth, Smith, Mirka, Gugusheff, Jessica, You, Hui, Qin Li, Shu, Dugdale, Sarah, Moore, Julie, Philpot, Shoni, Pfeiffer, Rhonda, Thomas, Helen, Silva Ragaini, Bruna, Venn, Alison, Evans, Sue, Te Marvelde, Luc, Savietto, Vedrana, Trevithick, Richard, Currow, David, Fowler, Christine, and Lewis, Chris
- The Lancet Child & Adolescent Health; June 2022, Vol. 6 Issue: 6 p409-431, 23p
- Abstract
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Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0–14 years) and adults (aged 15–99 years) diagnosed with a haematological malignancy during 2000–14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0–24 years).
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Dioverti MV, Gaston DC, Morris CP, Huff CA, Jain T, Jones R, Anders V, Lederman H, Saunders J, Mostafa HH, and Avery RK
Open forum infectious diseases [Open Forum Infect Dis] 2022 May 26; Vol. 9 (6), pp. ofac064. Date of Electronic Publication: 2022 May 26 (Print Publication: 2022).
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Profoundly B-cell-depleted patients can have prolonged severe acute respiratory syndrome coronavirus 2 infections with evidence of active viral replication, due to inability to mount an adequate humoral response to clear the virus. We present 3 B-cell-depleted patients with prolonged coronavirus disease 2019 infection who were successfully treated with a combination of casirivimab/imdevimab and remdesivir.
(© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)
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Lee H, Wiggermann V, Rauscher A, Kames C, Beg MF, Popuri K, Tam R, Lam K, Jacova C, Shahinfard E, Sossi V, Pettersen JA, and Hsiung GR
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques [Can J Neurol Sci] 2022 May 26, pp. 1-14. Date of Electronic Publication: 2022 May 26.
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Background: A large proportion of Alzheimer's disease (AD) patients have coexisting subcortical vascular dementia (SVaD), a condition referred to as mixed dementia (MixD). Brain imaging features of MixD presumably include those of cerebrovascular disease and AD pathology, but are difficult to characterize due to their heterogeneity.
Objective: To perform an exploratory analysis of conventional and non-conventional structural magnetic resonance imaging (MRI) abnormalities in MixD and to compare them to those observed in AD and SVaD.
Methods: We conducted a cross-sectional, region-of-interest-based analysis of 1) hyperintense white-matter signal abnormalities (WMSA) on T2-FLAIR and hypointense WMSA on T1-weighted MRI; 2) diffusion tensor imaging; 3) quantitative susceptibility mapping; and 4) effective transverse relaxation rate (R2*) in N = 17 participants (AD:5, SVaD:5, MixD:7). General linear model was used to explore group differences in these brain imaging measures.
Results: Model findings suggested imaging characteristics specific to our MixD group, including 1) higher burden of WMSAs on T1-weighted MRI (versus both AD and SVaD); 2) frontal lobar preponderance of WMSAs on both T2-FLAIR and T1-weighted MRI; 3) higher fractional anisotropy values within normal-appear white-matter tissues (versus SVaD, but not AD); and 4) lower R2* values within the T2-FLAIR WMSA areas (versus both AD and SVaD).
Conclusion: These findings suggest a preliminary picture of the location and type of brain imaging characteristics associated with MixD. Future imaging studies may employ region-specific hypotheses to distinguish MixD more rigorously from AD or SVaD.
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Gao RZ, Mai VNT, Levinski N, Kormylo JM, Murdock RW, Dickerson CR, and Ren CL
Biomicrofluidics [Biomicrofluidics] 2022 May 03; Vol. 16 (3), pp. 034101. Date of Electronic Publication: 2022 May 03 (Print Publication: 2022).
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A proof of concept of a novel air microfluidics-enabled soft robotic sleeve to enable lymphedema treatment is presented. Compression sleeves represent the current, suboptimal standard of care, and stationary pumps assist with lymph drainage; however, effective systems that are truly wearable while performing daily activities are very scarce. This problematic trade-off between performance and wearability requires a new solution, which is addressed by an innovative microfluidic device. Its novelty lies in the use of light, small, and inexpensive air microfluidic chips (35 × 20 × 5 mm 3 in size) that bring three major advantages compared to their traditional counterparts. First, each chip is designed with 16 fluidic channels with a cross-sectional area varying from 0.04 to 1 mm 2 , providing sequential inflation and uniform deflation capability to eight air bladders, thereby producing intentional gradient compression to the arm to facilitate lymph fluid circulation. The design is derived from the fundamentals of microfluidics, in particular, hydraulic resistance and paths of least resistance. Second, the air microfluidic chip enables miniaturization of at least eight bulky energy-consuming valves to two miniature solenoid valves for control increasing wearability. Third, the air microfluidic chip has no moving parts, which reduces the noise and energy needed. The cost, simplicity, and scale-up potential of developing methods for making the system are also detailed. The sequential inflation, uniform deflation, and pressure gradient are demonstrated, and the resulted compression and internal air bladder pressure were evaluated. This air microfluidics-enabled sleeve presents tremendous potential toward future improvements in self-care lymphedema management.
(© 2022 Author(s).)
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Abedon AT, Teles MS, Alejo JL, Kim JD, Mitchell J, Chiang TPY, Avery RK, Tobian AAR, Levan ML, Warren DS, Massie AB, Garonzik-Wang JM, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 May 01; Vol. 106 (5), pp. e262-e263. Date of Electronic Publication: 2022 Feb 15.
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Antibodies, Viral, Antibody Formation, COVID-19 Vaccines, Humans, SARS-CoV-2, Transplant Recipients, COVID-19 prevention control, and Organ Transplantation adverse effects
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Competing Interests: D.L.S. received consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, Thermo Fisher Scientific, Regeneron, and AstraZeneca. M.L.L. is the Social Media Editor for Transplantation. R.K.A. has grant/research support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, and Takeda/Shire. The other authors declare no conflicts of interest.
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Mitchell J, Kim J, Alejo JL, Chiang TP, Karaba AH, Blankson JN, Aytenfisu TY, Chang A, Abedon AT, Avery RK, Tobian AA, Massie AB, Levan ML, Warren DS, Garonzik-Wang JM, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 May 01; Vol. 106 (5), pp. e264-e265. Date of Electronic Publication: 2022 Mar 14.
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Abatacept therapeutic use, Antibodies, Viral, COVID-19 Vaccines, Humans, Immunity, Cellular, SARS-CoV-2, Transplant Recipients, COVID-19 prevention control, and Kidney Transplantation adverse effects
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Competing Interests: D.L.S. has received consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, Thermo Fisher Scientific, Regeneron, and Astra Zeneca. A.H.K. has received consulting fees from Roche. R.K.A. has study/grant support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, Regeneron, Takeda/Shire, and Vir/GSK and is an Associate Reviewer for Transplantation. M.L.L. is the Social Media Editor for Transplantation. The other authors declare no conflicts of interest.
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Mitchell J, Chiang TP, Alejo JL, Chang A, Abedon AT, Avery RK, Tobian AAR, Massie AB, Levan ML, Warren DS, Garonzik-Wang JM, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 May 01; Vol. 106 (5), pp. e269-e270. Date of Electronic Publication: 2022 Mar 03.
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Antibodies, Viral, Antibody Formation, COVID-19 Vaccines, Humans, Immunosuppressive Agents adverse effects, Lung, Mycophenolic Acid, SARS-CoV-2, Vaccination, COVID-19 prevention control, and Transplant Recipients
- Abstract
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Competing Interests: D.L.S. received consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, and Thermo Fisher Scientific. R.K.A. has study/grant support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, Regeneron, Takeda/Shire, and Vir/GSK, and he is an associate editor for Transplantation. M.L.L. is the Social Media Editor for Transplantation. The other authors declare no conflicts of interest.
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Abedon AT, Alejo JL, Kim JD, Thomas L, Mitchell J, Chiang TPY, Avery RK, Tobian AAR, Levan ML, Warren DS, Massie AB, Garonzik-Wang JM, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 May 01; Vol. 106 (5), pp. e281-e283. Date of Electronic Publication: 2022 Jan 19.
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Antibodies, Viral, COVID-19 Vaccines, Humans, Kinetics, SARS-CoV-2, Transplant Recipients, COVID-19 prevention control, and Organ Transplantation adverse effects
- Abstract
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Competing Interests: D.L.S. has received consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, Thermo Fisher Scientific, Regeneron, and Astra Zeneca. R.K.A. has study/grant support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, Regeneron, Takeda/Shire, and Vir/GSK and is an Associate Reviewer for Transplantation. M.L.L. is the Social Media Editor for Transplantation. The other authors declare no conflicts of interest.
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Kulkarni R, Caster JM, Robin A, Hajishengallis E, Stoopler ET, and Tanaka TI
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [Spec Care Dentist] 2022 May; Vol. 42 (3), pp. 308-311. Date of Electronic Publication: 2021 Nov 12.
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Child, Dementia, Dental Care, Humans, Amelogenesis Imperfecta therapy, Epilepsy, and Intellectual Disability
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Introduction: Kohlschutter-Tonz syndrome (KTS) is a rare, genetic condition, which typically manifests as a triad of symptoms: 1) amelogenesis imperfecta, 2) infantile onset epilepsy, and 3) intellectual disability. The condition poses dental treatment challenges given the manifestation of amelogenesis imperfecta. Additional considerations are needed to medically manage these patients who present with epilepsy and intellectual disability.
Case Report: Our patient presented with multiple restorative needs, was treated under general anesthesia, and maintained good oral outcomes with close follow-up.
Discussion: To the best of our knowledge, this is the first case report which documents comprehensive dental management of a pediatric patient with KTS.
(© 2021 Special Care Dentistry Association and Wiley Periodicals LLC.)
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Crandall J, Coatsworth-Puspoky R, Schlegel K, Beker L, McLelland VC, and Martin LS
Dementia (London, England) [Dementia (London)] 2022 May; Vol. 21 (4), pp. 1173-1199. Date of Electronic Publication: 2022 Jan 26.
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Aged, Canada, Hospitals, Humans, Program Evaluation, Dementia therapy, and Education, Distance
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Older adults with dementia, when hospitalised, frequently experience responsive behaviours. Staff struggle to manage responsive behaviours without specific education. We aimed to enhance staff knowledge and confidence with care for older adults with dementia and responsive behaviours on medicine units at a Canadian hospital. An online dementia education program was disseminated to staff as part of a broader quality improvement project. Gentle Persuasive Approaches (GPA) encourages staff to reframe responsive behaviours as self-protective expressions of unmet needs and learn to assess their meaning. Participants completed online quantitative and qualitative measures of self-efficacy, competence and knowledge in dementia care at three times: immediate pre-, immediate post- and six to eight weeks post-GPA eLearning. Immediately post-GPA, participants showed significant increases relative to baseline in dementia care self-efficacy, competence and knowledge. Self-efficacy scores increased further eight weeks post-GPA. Before GPA, few participants described dementia-specific strategies for de-escalating a patient's agitation. Eight weeks post-GPA, participants described application of tailored, person-centred, non-pharmacological interventions and successful application of GPA strategies. GPA eLearning strengthened staff preparedness to interact with older adults experiencing responsive behaviours, thus enhancing their care.
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Kurella Tamura, Manjula, Gaussoin, Sarah, Pajewski, Nicholas M., Zaharchuk, Greg, Freedman, Barry I., Rapp, Stephen R., Auchus, Alexander P., Haley, William E., Oparil, Suzanne, Kendrick, Jessica, Roumie, Christianne L., Beddhu, Srinivasan, Cheung, Alfred K., Williamson, Jeff D., Detre, John A., Dolui, Sudipto, Bryan, R. Nick, Nasrallah, Ilya M., Whelton, Paul, Johnson, Karen C., Snyder, Joni, Bild, Diane, Bonds, Denise, Cook, Nakela, Cutler, Jeffrey, Fine, Lawrence, Kaufmann, Peter, Kimmel, Paul, Launer, Lenore, Moy, Claudia, Riley, William, Ryan, Laurie, Snyder, Joni, Tolunay, Eser, Yang, Song, Reboussin, David, Williamson, Jeff, Ambrosius, Walter T., Applegate, William, Evans, Greg, Foy, Capri, Freedman, Barry I., Kitzman, Dalane, Lyles, Mary, Pajewski, Nick, Rapp, Steve, Rushing, Scott, Shah, Neel, Sink, Kaycee M., Vitolins, Mara, Wagenknecht, Lynne, Wilson, Valerie, Perdue, Letitia, Woolard, Nancy, Craven, Tim, Garcia, Katelyn, Gaussoin, Sarah, Lovato, Laura, Newman, Jill, Lovato, James, Lu, Lingyi, McLouth, Chris, Russell, Greg, Amoroso, Bobby, Davis, Patty, Griffin, Jason, Harris, Darrin, King, Mark, Lane, Kathy, Roberson, Wes, Steinberg, Debbie, Ashford, Donna, Babcock, Phyllis, Chamberlain, Dana, Christensen, Vickie, Cloud, Loretta, Collins, Christy, Cook, Delilah, Currie, Katherine, Felton, Debbie, Harpe, Stacy, Howard, Marjorie, Lewis, Michelle, Nance, Pamela, Puccinelli-Ortega, Nicole, Russell, Laurie, Walker, Jennifer, Craven, Brenda, Goode, Candace, Troxler, Margie, Davis, Janet, Hutchens, Sarah, Killeen, Anthony A., Lukkari, Anna M., Ringer, Robert, Dillard, Brandi, Archibeque, Norbert, Warren, Stuart, Sather, Mike, Pontzer, James, Taylor, Zach, Soliman, Elsayed Z., Zhang, Zhu-Ming, Li, Yabing, Campbell, Chuck, Hensley, Susan, Hu, Julie, Keasler, Lisa, Barr, Mary, Taylor, Tonya, Bryan, R. 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- American Journal of Kidney Diseases; May 2022, Vol. 79 Issue: 5 p677-687.e1
- Abstract
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The safety of intensive blood pressure (BP) targets is controversial for persons with chronic kidney disease (CKD). We studied the effects of hypertension treatment on cerebral perfusion and structure in individuals with and without CKD.
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68. Disseminated Intravascular Coagulation in Varying Age Groups Based on Clinical Conditions. [2022]
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Geyer-Roberts E, Akhand T, Blanco A, Jose R, Chowdhury N, Ea M, Gutierrez E, Balbuena J, Anagnostis S, Henderson C, Fazio A, Burpee A, and Jacobs RJ
Cureus [Cureus] 2022 Apr 21; Vol. 14 (4), pp. e24362. Date of Electronic Publication: 2022 Apr 21 (Print Publication: 2022).
- Abstract
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Disseminated intravascular coagulation (DIC) is a serious syndrome characterized by the systemic activation of blood coagulation resulting in the thrombosis of vessels leading to organ dysfunction and severe bleeding. When physicians try to treat DIC, it is imperative to diagnose and treat the underlying conditions. Anyone can be affected by DIC, but vulnerable groups such as pediatric populations, pregnant women and the elderly may be at higher risk. In this review, the current literature on DIC in pregnancy, the pediatric population, and the elderly is reported. This review also highlights the similarities and differences in the etiology, clinical presentation, diagnosis, and management of DIC in the aforementioned groups (i.e., pediatrics, pregnant women, and the elderly). Findings from this study may help increase awareness about various presentations of DIC in these groups to facilitate rapid recognition of symptoms leading to correct diagnoses.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Geyer-Roberts et al.)
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- Nature; April 2022, Vol. 604 Issue: 7906 p502-508, 7p
- Abstract
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Schizophrenia has a heritability of 60–80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the central nervous system, but not in other tissues or cell types. Using fine-mapping and functional genomic data, we identify 120 genes (106 protein-coding) that are likely to underpin associations at some of these loci, including 16 genes with credible causal non-synonymous or untranslated region variation. We also implicate fundamental processes related to neuronal function, including synaptic organization, differentiation and transmission. Fine-mapped candidates were enriched for genes associated with rare disruptive coding variants in people with schizophrenia, including the glutamate receptor subunit GRIN2Aand transcription factor SP4, and were also enriched for genes implicated by such variants in neurodevelopmental disorders. We identify biological processes relevant to schizophrenia pathophysiology; show convergence of common and rare variant associations in schizophrenia and neurodevelopmental disorders; and provide a resource of prioritized genes and variants to advance mechanistic studies.
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Lim J, Pavalagantharajah S, Verschoor CP, Lentz E, Loeb M, Levine M, Smieja M, Mbuagbaw L, Kalina D, Tarride JE, O'Shea T, Cvetkovic A, van Gaalen S, Findlater AR, Lennox R, Bassim C, Lokker C, and Alvarez E
PloS one [PLoS One] 2022 Apr 20; Vol. 17 (4), pp. e0266663. Date of Electronic Publication: 2022 Apr 20 (Print Publication: 2022).
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Hospitalization, Humans, Communicable Diseases complications, Communicable Diseases epidemiology, Drug Users, Endocarditis complications, Substance Abuse, Intravenous complications, and Substance Abuse, Intravenous epidemiology
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Injection drug use poses a public health challenge. Clinical experience indicates that people who inject drugs (PWID) are hospitalized frequently for infectious diseases, but little is known about outcomes when admitted. Charts were identified from local hospitals between 2013-2018 using consultation lists and hospital record searches. Included individuals injected drugs in the past six months and presented with infection. Charts were accessed using the hospital information system, undergoing primary and secondary reviews using Research Electronic Data Capture (REDCap). The Wilcoxon rank-sum test was used for comparisons between outcome categories. Categorical data were summarized as count and frequency, and compared using Fisher's exact test. Of 240 individuals, 33% were admitted to the intensive care unit, 36% underwent surgery, 12% left against medical advice (AMA), and 9% died. Infectious diagnoses included bacteremia (31%), abscess (29%), endocarditis (29%), cellulitis (20%), sepsis (10%), osteomyelitis (9%), septic arthritis (8%), pneumonia (7%), discitis (2%), meningitis/encephalitis (2%), or other (7%). Sixty-six percent had stable housing and 60% had a family physician. Fifty-four percent of patient-initiated discharges were seen in the emergency department within 30 days and 29% were readmitted. PWID are at risk for infections. Understanding their healthcare trajectory is essential to improve their care.
Competing Interests: The authors have declared that no competing interests exist.
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Menghoum N, Vos JL, Pouleur AC, Nijveldt R, and Gerber BL
European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2022 Apr 18; Vol. 23 (5), pp. 587-589.
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Contrast Media, Humans, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Myocardium pathology, Predictive Value of Tests, Cardiomyopathies diagnostic imaging, Cardiomyopathies pathology, and Gadolinium
72. Genetic variants associated with longitudinal changes in brain structure across the lifespan. [2022]
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Brouwer RM, Klein M, Grasby KL, Schnack HG, Jahanshad N, Teeuw J, Thomopoulos SI, Sprooten E, Franz CE, Gogtay N, Kremen WS, Panizzon MS, Olde Loohuis LM, Whelan CD, Aghajani M, Alloza C, Alnæs D, Artiges E, Ayesa-Arriola R, Barker GJ, Bastin ME, Blok E, Bøen E, Breukelaar IA, Bright JK, Buimer EEL, Bülow R, Cannon DM, Ciufolini S, Crossley NA, Damatac CG, Dazzan P, de Mol CL, de Zwarte SMC, Desrivières S, Díaz-Caneja CM, Doan NT, Dohm K, Fröhner JH, Goltermann J, Grigis A, Grotegerd D, Han LKM, Harris MA, Hartman CA, Heany SJ, Heindel W, Heslenfeld DJ, Hohmann S, Ittermann B, Jansen PR, Janssen J, Jia T, Jiang J, Jockwitz C, Karali T, Keeser D, Koevoets MGJC, Lenroot RK, Malchow B, Mandl RCW, Medel V, Meinert S, Morgan CA, Mühleisen TW, Nabulsi L, Opel N, de la Foz VO, Overs BJ, Paillère Martinot ML, Redlich R, Marques TR, Repple J, Roberts G, Roshchupkin GV, Setiaman N, Shumskaya E, Stein F, Sudre G, Takahashi S, Thalamuthu A, Tordesillas-Gutiérrez D, van der Lugt A, van Haren NEM, Wardlaw JM, Wen W, Westeneng HJ, Wittfeld K, Zhu AH, Zugman A, Armstrong NJ, Bonfiglio G, Bralten J, Dalvie S, Davies G, Di Forti M, Ding L, Donohoe G, Forstner AJ, Gonzalez-Peñas J, Guimaraes JPOFT, Homuth G, Hottenga JJ, Knol MJ, Kwok JBJ, Le Hellard S, Mather KA, Milaneschi Y, Morris DW, Nöthen MM, Papiol S, Rietschel M, Santoro ML, Steen VM, Stein JL, Streit F, Tankard RM, Teumer A, van 't Ent D, van der Meer D, van Eijk KR, Vassos E, Vázquez-Bourgon J, Witt SH, Adams HHH, Agartz I, Ames D, Amunts K, Andreassen OA, Arango C, Banaschewski T, Baune BT, Belangero SI, Bokde ALW, Boomsma DI, Bressan RA, Brodaty H, Buitelaar JK, Cahn W, Caspers S, Cichon S, Crespo-Facorro B, Cox SR, Dannlowski U, Elvsåshagen T, Espeseth T, Falkai PG, Fisher SE, Flor H, Fullerton JM, Garavan H, Gowland PA, Grabe HJ, Hahn T, Heinz A, Hillegers M, Hoare J, Hoekstra PJ, Ikram MA, Jackowski AP, Jansen A, Jönsson EG, Kahn RS, Kircher T, Korgaonkar MS, Krug A, Lemaitre H, Malt UF, Martinot JL, McDonald C, Mitchell PB, Muetzel RL, Murray RM, Nees F, Nenadić I, Oosterlaan J, Ophoff RA, Pan PM, Penninx BWJH, Poustka L, Sachdev PS, Salum GA, Schofield PR, Schumann G, Shaw P, Sim K, Smolka MN, Stein DJ, Trollor JN, van den Berg LH, Veldink JH, Walter H, Westlye LT, Whelan R, White T, Wright MJ, Medland SE, Franke B, Thompson PM, and Hulshoff Pol HE
Nature neuroscience [Nat Neurosci] 2022 Apr; Vol. 25 (4), pp. 421-432. Date of Electronic Publication: 2022 Apr 05.
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Aging genetics, Brain, Humans, Magnetic Resonance Imaging, Genome-Wide Association Study, and Longevity genetics
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Human brain structure changes throughout the lifespan. Altered brain growth or rates of decline are implicated in a vast range of psychiatric, developmental and neurodegenerative diseases. In this study, we identified common genetic variants that affect rates of brain growth or atrophy in what is, to our knowledge, the first genome-wide association meta-analysis of changes in brain morphology across the lifespan. Longitudinal magnetic resonance imaging data from 15,640 individuals were used to compute rates of change for 15 brain structures. The most robustly identified genes GPR139, DACH1 and APOE are associated with metabolic processes. We demonstrate global genetic overlap with depression, schizophrenia, cognitive functioning, insomnia, height, body mass index and smoking. Gene set findings implicate both early brain development and neurodegenerative processes in the rates of brain changes. Identifying variants involved in structural brain changes may help to determine biological pathways underlying optimal and dysfunctional brain development and aging.
(© 2022. The Author(s), under exclusive licence to Springer Nature America, Inc.)
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Vos JL, Butcher SC, Fortuni F, Galloo X, Rodwell L, Vonk MC, Bax JJ, van Leuven SI, de Vries-Bouwstra JK, Snoeren M, El Messaoudi S, Marsan NA, and Nijveldt R
Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2022 Mar 17; Vol. 9, pp. 845359. Date of Electronic Publication: 2022 Mar 17 (Print Publication: 2022).
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Introduction: Right ventricular (RV) function is of particular importance in systemic sclerosis (SSc), since common SSc complications, such as interstitial lung disease and pulmonary hypertension may affect RV afterload. Cardiovascular magnetic resonance (CMR) is the gold standard for measuring RV function. CMR-derived RV and right atrial (RA) strain is a promising tool to detect subtle changes in RV function, and might have incremental value, however, prognostic data is lacking. Therefore, the aim of this study was to evaluate the prognostic value of RA and RV strain in SSc.
Methods: In this retrospective study, performed at two Dutch hospitals, consecutive SSc patients who underwent CMR were included. RV longitudinal strain (LS) and RA strain were measured. Unadjusted cox proportional hazard regression analysis and likelihood ratio tests were used to evaluate the association and incremental value of strain parameters with all-cause mortality.
Results: A total of 100 patients (median age 54 [46-64] years, 42% male) were included. Twenty-four patients (24%) died during a follow-up of 3.1 [1.8-5.2] years. RA reservoir [Hazard Ratio (HR) = 0.95, 95% CI 0.91-0.99, p = 0.009] and conduit strain (HR = 0.93, 95% CI 0.88-0.98, p = 0.008) were univariable predictors of all-cause mortality, while RV LS and RA booster strain were not. RA conduit strain proved to be of incremental value to sex, atrial fibrillation, NYHA class, RA maximum volume indexed, and late gadolinium enhancement ( p < 0.05 for all).
Conclusion: RA reservoir and conduit strain are predictors of all-cause mortality in SSc patients, whereas RV LS is not. In addition, RA conduit strain showed incremental prognostic value to all evaluated clinical and imaging parameters. Therefore, RA conduit strain may be a useful prognostic marker in SSc patients.
Competing Interests: JV-B received consulting fees from AbbVie, Janssen, and Boehringer Ingelheim, and research grants from Roche, Galapagos, and Janssen. MV received research grants from Boehringer Ingelheim, Ferrer, Galapagos, and Janssen, and consulting fees of Boehringer Ingelheim, Corbus, and Janssen. NM received speaker fees from GE Healthcare and Abbott Vascular, and also participated in the Medical Advisory Board of Philips Ultrasound. RN received research grants from Biotronik and Philips, and consulting fees of Sanofi Genzyme and Bayer. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2022 Vos, Butcher, Fortuni, Galloo, Rodwell, Vonk, Bax, van Leuven, de Vries-Bouwstra, Snoeren, El Messaoudi, Marsan and Nijveldt.)
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Nicholas, Jacqueline, Belviso, Nick, Banerjee, Geentanjoli, Geremakis, Caroline, Avila, Robin, and Bodhinathan, Karthik
- Multiple Sclerosis & Related Disorders; Mar2022, Vol. 59, pN.PAG-N.PAG, 1p
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van Bakel BMA, van den Heuvel FMA, Vos JL, Rotbi H, Bakker EA, Nijveldt R, Thijssen DHJ, and Eijsvogels TMH
Journal of clinical medicine [J Clin Med] 2022 Feb 19; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 19.
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Many patients with COVID-19 experience severe and even fatal disease. Survivors may have long-term health consequences, but data on physical activity and sedentary behaviour are scarce. Therefore, we objectively assessed physical activity (PA) patterns among post-hospitalised patients with COVID-19 and explored associations with patient characteristics, disease severity and cardiac dysfunction. We objectively assessed PA, sedentary behaviour and sleep duration for 24 h/day during 8 days at 3-6 months after COVID-19 hospitalisation. PA and sedentary time were compared across pre-defined subgroups based on patient and disease characteristics, cardiac biomarker release during hospitalisation, abnormal transthoracic echocardiogram at 3-6 months post-hospitalisation and persistence of symptoms post-discharge. PA and sedentary behaviour were assessed in 37 patients (60 ± 10 years old; 78% male). Patients spent 4.2 [3.2; 5.3] h/day light-intensity PA and 1.0 [0.8; 1.4] h/day moderate-to-vigorous intensity PA. Time spent sitting was 9.8 [8.7; 11.2] h/day, which was accumulated in 6 [5; 7] prolonged sitting bouts (≥30 min) and 41 [32; 48] short sitting bouts (<30 min). No differences in PA and sedentary behaviour were found across subgroups, but sleep duration was higher in patients with versus without persistent symptoms (9.1 vs. 8.3 h/day, p = 0.02). Taken together, high levels of sedentary time are common at 3-6 months after COVID-19 hospitalisation, whilst PA and sedentary behaviour are not impacted by patient or disease characteristics.
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Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abdallah, Nabeel, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Basir, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdullah, Abdullah, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Ul-Amna, Abeer, Abernethy, Katrina, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abraham, Miriam, Abraham, Tizzy, Abraheem, Abraheem, Abrams, Judith, Abu, Hyacinth-John, Abu-Arafeh, Ahmed, Abubacker, Syed M, Abung, Akata, Aceampong, Yaa, Achara, Amaka, Acharya, Devikumar, Acheampong, Sarah, Acheson, Janet, Acosta, Andres, Acton, Catherine, Adabie-Ankrah, Jacqueline, Adam, Fiona, Adam, Matthew, Adamali, Huzaifa, Adams, Carol, Adams, Charlotte, Adams, Kate, Adams, Richard, Adams, Tim, Adatia, Krishma, Adcock, Kirsty, Adebiyi, Ade, Adegoke, Ken, Adell, Vicki, Adenwalla, Sherna, Adesemoye, Oluwasegun A, Adewunmi, Emmanuel O, Adeyemi, Joyce, Adhikari, Binay, Adhikary, Rina, Adkins, Gabrielle, Adnan, Adnan, Aeron-Thomas, John, Affleck, Debbie, Afnan, Carmel, Afridi, Muhammad, Aftab, Zainab A, Agarwal, Meenakshi, Agbeko, Rachel, Agbo, Chris, Aggarwal, Sunil, Aghababaie, Arameh, Ahamed Sadiq, Shafana, Ahammed Nazeer, Mohamed H, Ahmad, Mohammad, Ahmad, Syed, Ahmed, Asim, Ahmed, Bilal, Ahmed, Forizuddin, Ahmed, Hamze, Ahmed, Irshad, Ahmed, Khaled, Ahmed, Liban, Ahmed, Mahin, Ahmed, Maria C, Ahmed, Muhammad S, Ahmed, Naseer, Ahmed, Nausheen, Ahmed, Osama, Ahmed, Rajia A, Ahmed, Rizwan, Ahmed, Saif, Ahmed, Sammiya, Ahmed, Syed, Ahmed, Syed Haris, Ahmed Ali, Roa, Ahmed, Sana, Ahmer, Sana, Ail, Dhiraj, Ainsworth, Mark, Aissa, Myriam, Aitken, Lindianne, Ajay, Bini, Ajibode, Abdulakeem, Ajmi, Ayesha, Akhtar, Nasim, Akhtar, Nauman, Akili, Suha, Akindolie, Oludoyinsola, Akinfenwa, Yinka, Akinkugbe, Olugbenga, Akinpelu, Ibrahim, Aktinade, Olugbenro, Al Aaraj, Ahmad S A R, Al Balushi, Asma, Al Dakhola, Majd, Al Swaifi, Aladdin, Al-Abadi, Eslam, Aladangady, Narendra, Alam, Ayaz, Alam, Sajid, Al-Asadi, Abbas, Alatzoglou, Kyriaki, Albert, Paul, Albon, Lorraine, Alcorn, Gemma, Alcorn, Stephen, Aldana, Aggie, Alderdice, David, Aldouri, Rayan, Aldridge, Jonathan, Aldridge, Nicolas, Alegria, Ana, Alexander, Alison, Alexander, John, Alexander, Peter D G, Al-Fori, Julyan, Alghazawi, Laith, Al-Hakim, Bahij, Al-Hity, Shams, Ali, Ali, Ali, Asad, Ali, Fawzia R, Ali, Jawad, Ali, Mariam, Ali, Mohammad, Ali, Nayab, Ali, Oudai, Ali, Sakina, Ali, Syed, Alina, Abid, Aliyuda, Fine, Alizadeh, Katrin, Al-Jibury, Maithem, Al-Juboori, Saba, Al-Khalil, Majid, Alkhusheh, Moutaz, Allan, Fiona, Allanson, Alison, Allcock, Robert, Allen, Eireann, Allen, Kerry, Allen, Louise, Allen, Poppy, Allen, Rebecca, Allen, Sam, Allen, Sharon, Allen, Simon, Allison, Kathryn, Allman, Bethan, Allsop, Lynne, Al-Moasseb, Hassan, Al-Obaidi, Magda, Alomari, Lina, Al-Rabahi, Akram, Al-Ramadhani, Bahar, Al-Saadi, Zayneb, Alshaer, Inji, Al-Shahi Salman, Rustam, Al-Shamkhani, Warkaq, Al-Sheklly, Bashar, Altaf, Sara, Alvarez, Mary, Alzetani, Maysaa, Amamou, Susan, Amar, Noor, Ambalavanan, Sakkarai, Ambrogetti, Robert, Ambrose, Chris, Ameen, Amir, Amezaga, Maria R, Amin, Allison, Amin, Amina, Amin, Kanish, Amin, Syed, Amin, Tara, Amjad, Amjad, Amjad, Neelma, Amosun, Victoria, Amsha, Khaled, Amy, Pugh, Anand, Atul, Anandappa, Samantha, Anderson, Julie, Anderson, Laura, Anderson, Michelle, Anderson, Nicola, Anderson, Rachel, Anderson, Rory, Anderson, Wendy, Andreou, Prematie, Andrews, Angela, Andrews, Antonette, Andrews, Jill, Aneke, Kanayochukwu, Ang, Andrew, Ang, Wan Wei, Angel, Tammy, Angela, Aramburo, Angelini, Paola, Anguvaa, Lazarus, Anichtchik, Oleg, Anim-Somuah, Millicent, Aniruddhan, Krishnan, Annett, Jessica, Anning, Louise, Anstey, Patrick J, Anstey, Rebekah, Anthony, Alpha, Anthony-Pillai, Aaron, Antill, Philip, Antonina, Zhelyazkova, Anu, Varghese, Anwar, Muhammad, Apostolopoulos, Aristeidis, Appleby, Sarah, Appleyard, Diane, Aquino, Maia Far, Araba, Bianca, Aransiola, Samuel, Araujo, Mariana, Archer, Ann, Archer, Denise, Archer, Simon, Ardley, Christian, Arias, Ana-Maria, Arimoto, Ryoki, Arkley, Charlotte, Armah, Charlotte, Armata, Ilianna, Armitage, Adam, Armstrong, Ceri, Armstrong, Maureen, Armstrong, Sonia, Armtrong, Philippa, Arndt, Heike, Arnison-Newgass, Clare, Arnold, David, Arnold, Rachael, Arora, Dhawal, Arora, Kavan, Arora, Pardeep, Arora, Rishi, Arter, Arslam, Arya, Ayush, Arya, Rita, Asandei, Denisa, Asghar, Adeeba, Ashbrook-Raby, Catherine, Ashby, Helen, Ashcroft, Jan, Ashcroft, John, Ashcroft, Samuel, Asher, Georgia, Ashfaq, Ayesha, Ashish, Abdul, Ashman-Flavell, Sally, Ashok, Sundar, Ashour, Abd-El-Aziz, Ashraf, Muhammad Z, Ashraf, Saima, Ashraq, Mohammad B, Ashton, Deborah, Ashton, Susan, Ashworth, Andrew, Ashworth, Rebecca, Aslam, Arshia, Asogan, Harshini, Asrar, Atif, Assaf, Omar, Astin-Chamberlain, Raine, Athorne, Deborah, Atkins, Billie, Atkins, Christopher, Atkins, Stacey, Atkinson, John, Atkinson, Vicki, Atraskiewicz, Brygitta, Attia, Abdul A, Aubrey, Paula, Aujayeb, Avinash, Aung, Aye CT, Aung, Hnin, Aung, Kyaw T, Aung, Yin, Aung, Zaw M, Austin, Emily, Austin, Karen, Auwal, Abdusshakur, Avery, Miriam, Aveyard, Nicholas, Avis, Joanne, Aviss, Georgina, Avram, Cristina, Avram, Paula, Awadzi, Gabriel, Awan, Atia, Aya, Aszad, Ayaz, Eman, Ayers, Amanda, Azam, Jawwad, Azharuddin, Mohammed, Aziz, Ghazala, Aziz, N, Azkoul, Ali, Azman Shah, Ashaari, Azzopardi, Giada, Azzoug, Hocine, Babatunde, Fiyinfoluwa, Babi, Melvin, Babiker, Babiker, Babington, Gayna, Babirecki, Matthew, Babores, Marta, Babs-Osibodu, Adetona O, Bacciarelli, Sammy, Bachar, Roudi, Bacon, Gina, Bacon, Jenny, Badal, Bibi, Badhan, Gurpreet R, Badhrinarayanan, Shreya, Bae, Joseph P, Baggaley, Alice, Baggott, Amy, Bagley, Graham, Bagmane, Dinesh, Bagshaw, Lynsey, Bahadori, Kasra, Bailey, James, Bailey, Katie, Bailey, Lindsey, Bailey, Liz, Bailey, Morgan, Bailey, Pippa, Bailey, Sarah, Baillie, Hamish, Baillie, J Kenneth, Bain, Jennifer, Bains, Vikram, Baird, David, Baird, Kevin, Baird, Susan, Baird, Tracy, Baird, Yolanda, Bajandouh, Aiysha, Baker, Evelyn, Baker, Johanne, Baker, Josephine, Baker, Kenneth, Baker, Rebecca, Baker, Terri-Anne, Baker, Victoria, Bakere, Hugh, Bakerly, Nawar, Baker-Moffatt, Michelle, Bakhtiar, Nauman, Bakoulas, Panos, Balachandran, Niranjan, Balan, Andrea, Balaskas, Theodosios, Balasubramaniam, Madhu, Balcombe, Alison, Baldwin, Alexander, Baldwin, Ashley, Baldwin, Caron, Baldwin, Danielle, Baldwin-Jones, Rebekah, Balfour, James, Ball, Matthew, Ballard, K, Balluz, Ismael, Balmforth, Craig, Balogh, Emese, Baluwala, Amir, Bambridge, Gabby, Bamford, Alasdair, Bamford, Amy, Bamford, Peter, Bamgboye, Adefunke, Bancroft, Elizabeth, Bancroft, Hollie, Banda, Joyce, Bandaru, Krishna, Bandi, Srini, Bandla, Nageswar, Bandyopadhyam, Somaditya, Banerjee, Amit, Banerjee, Ritwik, Banks, Harrison, Banks, Luke, Banks, Paul, Bannister, Oliver, Banton, Laura, Bao, Tran, Baptist, Mariamma, Baqai, Tanya, Baral, Ananya M, Baramova, Desislava, Barber, Russel, Barbon, Emma, Barbosa, Miriam, Barbosa, Monica, Barbour, Jamie, Barclay, Alexander, Barclay, Claire, Bardsley, George, Bareford, Stephanie, Bari, Shahedal, Barimbing, Morris, Barker, Amy, Barker, Debbie, Barker, Helen, Barker, Joseph, Barker, Leon, Barker, Oliver, Barker-Williams, Kerry, Barkha, Sinha, Barla, Juliana, Barlow, Gavin, Barlow, Richard, Barlow, Valerie, Barnacle, James, Barnard, Alex, Barnes, Debi, Barnes, Nicky, Barnes, Theresa, Barnetson, Calum, Barnett, Amy, Barnett-Vanes, Ashton, Barnsley, William, Barr, Andrew, Barr, David, Barratt, Shaney, Barrera, Manuella, Barrett, Amy, Barrett, Fiona, Barrett, Jessica, Bartholomew, Jazz, Bartlett, Claire, Bartlett, Georgina, Barton, Greg, Barton, Jill, Barton, Lorna, Barton, Rachael, Baruah, Rosaleen, Baryschpolec, Sonia, Bashyal, Archana, Basker, Betsy, Basnyat, Buddha, Basoglu, Ayten, Bassett, John, Bassett, G, Bassford, Chris, Bassoy, Bengisu, Bastion, Victoria, Bastola, Anup, Basumatary, Anupam, Bate, Tristan, Bateman, Harry J, Bateman, Kathryn, Bateman, Vhairi, Bates, Eleanor, Bates, Hayley, Bates, Michelle, Bates, Simon, Batham, Sally, Batista, Ana, Batla, Amit, Batra, Dushyant, Batty, Harry, Batty, Thomas, Baum, Miranda, Baumber, Rachel, Bautista, Carina, Bawa, Fareha, Bawani, Fatima S, Bax, Simon, Baxter, Matt, Baxter, Nicola, Baxter, Zachary, Bayes, Hannah, Bazari, Farid, Bazaz, Rohit, Bazli, Ahmad, Beacham, Laura, Beadles, Wendy, Beak, Philip, Beale, Andy, Bearpark, Jack, Beaumont, Karen, Beaumont-Jewell, Dawn, Beaver, Theresa, Beavis, Sarah, Beazley, Christy, Beck, Sarah, Beckett, Virginia, Beckitt, Rosie, Beddall, Heidi, Beddows, Seonaid, Beeby, Deborah, Beech, Gail, Beecroft, Michelle, Beer, Sally, Beety, Jane, Bega, Gabriela, Begg, Alison, Begg, Susan, Beghini, Sara, Begum, Ayesha, Begum, Salman, Begum, Selina, Behan, Teresa, Behrouzi, Roya, Beishon, Jon, Beith, Claire, Belcher, James, Belfield, Holly, Belfield, Katherine, Belgaumkar, Ajay, Bell, Dina, Bell, Gareth, Bell, Gillian, Bell, Lauren, Bell, Louise, Bell, Nicholas, Bell, Pippa, Bell, Stephanie, Bell, Jennifer L, Bellamu, Jennifer, Bellamy, Mary, Bellini, Arianna, Bellis, Amanda, Bellis, Fionn, Bendall, Lesley, Benesh, Naveena, Benetti, Nicola, Benham, Leonie, Benison-Horner, Guy, Bennett, Ann, Bennett, Caroline, Bennett, Gillian, Bennett, Kristopher, Bennett, Lorraine, Bennett, Sara, Bennion, Karen, Benson, Vivienne, Bentley, Andrew, Bentley, James, Benton, Ian, Beranova, Eva, Beresford, Matthew, Bergin, Colin, Bergstrom, Malin, Bernatoniene, Jolanta, Berriman, Thomas, Berry, Zoe, Best, Kimberley, Bester, Ans-Mari, Beuvink, Yvonne, Bevan, Emily, Bevins, Sarah, Bewick, Tom, Bexley, Andrew, Beyatli, Sonay, Beynon, Fenella, Bhadi, Arjun, Bhagani, Sanjay, Bhakta, Shiv, Bhalla, Rekha, Bhandal, Khushpreet, Bhandal, Kulbinder, Bhandari, Ashwin, Bhandari, Sangam, Bhanot, Aashutosh, Bhanot, Ravina, Bhat, Prashanth, Bhatnagar, Rahul, Bhatt, Karan, Bhayani, Janki, Bhojwani, Deepika, Bhuiyan, Salimuzzaman, Bibby, Anna, Bibi, Fatima, Bibi, Naheeda, Bibi, Salma, Bicanic, Tihana, Bidgood, Sarah, Bigg, Julie, Biggs, Sarah, Biju, Alphonsa, Bikov, Andras, Billingham, Sophie, Billings, Jessica, Binns, Alice, BinRofaie, Muhammad, Bintcliffe, Oliver, Birch, Catherine, Birch, Jenny, Birchall, Katherine, Bird, Sam, Bird, Sumedha, Birt, Mark, Bishop, Kilanalei, Bishop, Linda, Bishop, Lisa, Bisnauthsing, Karen, Biswas, Nibedan, Biuk, Sahar, Blachford, Karen, Black, Ethel, Black, Helen, Black, Karen, Black, Mairead, Black, Polly, Blackgrove, Hayley, Blackledge, Bethan, Blackler, Joanne, Blackley, Samantha, Blackman, Helen, Blackstock, Caroline, Blakemore, Francesca, Blamey, Helen, Bland, Alison, Blane, Sujata, Blankley, Simon, Blaxill, Parry, Blaylock, Katie, Blazeby, Jane, Blencowe, Natalie, Bloom, Ben, Bloomfield, Jack, Bloss, Angela, Bloxham, Hannah, Blundell, Louise, Blunsum, Andrew, Blunt, Mark, Blyth, Ian, Blyth, Kevin, Blythe, Andrew, Blythe, Karen, Boampoaa, Marilyn, Bobie, Boniface, Bobruk, Karen, Bodalia, Pritesh N, Bodasing, Neena, Bodenham, Tanya, Boehmer, Gabriele, Boffito, Marta, Bohmova, Kristyna, Bohnacker, Niamh, Bokhandi, Sumit, Bokhar, Maria, Bokhari, Saba, Bokhari, Sakina, Bokhari, Syed O, Boles, Ambrose, Bond, Charlotte, Bond, Helena, Bond, Stuart, Bond, Thomas, Bone, Alice, Boniface, Georgia, Bonney, Lizzy, Boot, Sarah, Borbone, Joanne, Borman, Naomi, Boshir, Mamu, Bottrill, Fiona, Bough, Laura, Boughton, Hayley, Boult, Zoe, Bourke, Miriam, Bourke, Stephen, Bourne, Michelle, Bousfield, Rachel, Boustred, Lucy, Bowes, Alexandra, Bowes, Amy, Bowker, Philip, Bowman, Louise, Bowman, Simon, Bowmer, Rachel, Bowring, Angie, Bowyer, Helen, Boyd, Aileen, Boyd, Jenny, Boyd, Laura, Boyle, Namoi, Boyle, Pauline, Boyle, Rosalind, Boyles, Louise, Brace, Leanna, Bradder, Jodie, Bradley, Clare J, Bradley, Pamela, Bradley, Patrick, Bradley, Paul, Bradley-Potts, Joanne, Bradshaw, Lynne, Bradshaw, Zena, Brady, Rebecca, Brady, Shirin, Braganza, Denise, Branch, Marie, Brankin-Frisby, Thomas, Brannigan, Jamie, Brattan, Sophie, Bray, Fiona, Bray, Nancy, Brazil, Manny, Brear, Lucy, Brear, Tracy, Brearey, Stephen, Bremner, Laura, Brend, Morwenna, Bretland, Giovanna, Brewer, Chris, Bridgwood, Gavin, Brigham, Sara, Bright, John, Brightling, Chris, Brimfield, Lutece, Brinkworth, Elaine, Brittain-Long, Robin, Britten, Vianne, Broad, Lauren, Broad, Sarah, Broadhurst, Rosie, Broadley, Andrew, Broadway, Marie, Brockelsby, Christopher, Brocken, Megan, Brockley, Tomos, Brodsky, Mary, Brogan, Fiona, Brohan, Liz, Brokke, Felicity, Brolly, Jacob, Bromley, David, Brooke-Ball, Hannah, Brooker, Verity, Brookes, Matthew, Brooking, Deirdre, Brooks, Alison, Brooks, Karen, Brooks, Nicole, Brooks, Philip, Brooks, Rachel, Brooks, Sophie, Brooks, Tim, Broomhead, Natalie, Broughton, Chloe, Broughton, Nathaniel, Brouns, Matt, Brown, Alison, Brown, Ammani, Brown, Carly, Brown, Catrin, Brown, Ellen, Brown, Heather, Brown, Janet, Brown, Louise, Brown, Niall, Brown, Pauline, Brown, Rachel, Brown, Richard, Brown, Robert, Brown, Steven, Brown, Thomas, Brown, Tom, Browne, Bria, Browne, Charlotte, Browne, Duncan, Browne, Mitchell, Brownlee, Stephen, Brraka, Alba, Bruce, Johanna, Bruce, Michelle, Brudlo, Wojciech, Brunskill, Nigel, Brunton, Alan, Brunton, Margaret, Bryant, Meera, Buazon, April, Buch, Maya H, Buchan, Ruaridh, Buchanan, Ruaridh, Buche, Danielle, Buck, Amanda, Buckland, Matthew, Buckley, Laura, Buckley, Philip, Buckley, Sarah, Buckman, Carol, Bugg, George, Bujazia, Ramadan, Bukhari, Marwan, Bukhari, Shanze, Bulbulia, Richard, Bull, Alex, Bull, Damian, Bull, Rhian, Bull, Thomas, Bulteel, Naomi, Bumunarachchi, Kasun, Bungue-Tuble, Roneleeh, Burchett, Caroline, Burda, Dorota, Burden, Christy, Burden, Thomas G, Burgess, Mika, Burgess, Richard, Burgess, Sophia, Burman, Adrian, Burnard, Sara, Burnett, Caroline, Burns, Amy, Burns, Collette, Burns, James, Burns, Karen, Burrage, Daniel, Burrows, Kate, Burston, Claire, Burton, Ben, Burton, Fiona, Burton, Matthew, Butcher, Deborah, Butler, Aaron, Butler, Jessica, Butler, Joanne, Butler, Joshua, Butler, Peter, Butler, Susan, Butt, Al-Tahoor, Butt, Mohammad M, Butterworth, Caryl, Butterworth-Cowin, Nicola, Buttery, Robert, Buttle, Tom, Button, Heather, Buttress, Daniel, Byrne, Jane, Byrne, Wendy, Byrne-Watts, Victoria, Cabandugama, Amanda, Cade, Ruth, Cadwgan, Anthony, Cahyareny, Ajeng, Cairney, Donna, Calderwood, James, Caldow, Darren, Calisti, Giorgio, Callaghan, Debbie, Callaghan, Jennifer, Callens, Claire, Callum, Donaldson, Calver, Caroline, Cambell-Kelly, Melissa, Camburn, Tracey, Cameron, David R, Cameron, Eleanor, Cameron, Fraser, Cameron, Sarah, Cameron, Sheena, Camm, Christian, Cammack, Renee F D, Campbell, Alison, Campbell, Amy, Campbell, Barbara, Campbell, Bridget, Campbell, Debbie, Campbell, Helen, Campbell, Hilary, Campbell, Jonathan, Campbell, Mark, Campbell, Robyn, Campbell, Wynny, Campbell Hewson, Quentin, Camsooksai, Julie, Canclini, Lisa, Candido, Shaula M, Candlish, Janie, Caneja, Cielito, Cann, Alexandra, Cann, Johnathon, Cannan, Ruby, Cannon, Emma, Cannon, Michael, Cannon, Petra, Cannons, Vivienne, Cantliff, Jane, Caplin, Ben, Capocci, Santino, Caponi, Noemi, Capp, Angelika, Capstick, Thomas, Cardwell, Mary, Carey, Rachel, Carley, Simon, Carlin, Tammy, Carmichael, Samantha, Carnahan, Mandy, Caroline, Charlotte, Carpenter, Jodi, Carr, Sharon, Carrasco, Anna, Carrington, Zoe, Carroll, Amy, Carroll, Paul, Carter, Jonathan, Carter, Michael, Carter, Paul, Carter, Penny, Cartwright, Douglas, Cartwright, Jo-Anne, Carty, Claire, Carungcong, Jaime, Casey, Susan, Cassells, Annie, Castiello, Teresa, Castle, Gail, Castles, Bridget, Caswell, Melanie, Catana, Ana Maria, Cate, Heidi, Cathcart, Susanne, Cathie, Katrina, Catley, Christine, Catlow, Laura, Caudwell, Matthew, Cavazza, Anna, Cave, Luke, Cavinato, Simon, Cawa, Frianne, Cawley, Kathryn, Caws, Chloe, Cendl, Hankins, Century, Hannah, Cernova, Jeva, Cesay, Mansur, Cetti, Ed, Chabane, Stephanie, Chablani, Manish, Chabo, Cathleen, Chadwick, David, Chadwick, Julie, Chadwick, Robert, Chakkarapani, Ela, Chakraborty, Arup, Chakraborty, Mallinath, Chakravorty, Mollika, Chalise, Bimal, Chalmers, James, Chalmers, Richard, Chamberlain, Georgina, Chamberlain, Sarah, Chambers, Emma, Chambers, Jonathan, Chambers, Lucy, Chambers, Naomi, Chan, Alex, Chan, Carmen, Chan, Cheuk, Chan, Evelyn, Chan, Kayen, Chan, Kimberley, Chan, Ping, Chan, Rebekah (Pui-Ching), Chan, Xin Hui S, Chandler, Chris, Chandler, Heidi, Chandler, Kim J, Chandler, Stuart, Chandler, Zoe, Chandra, Sumit, Chandran, Navin, Chandrasekaran, Badrinathan, Chang, Yvonne, Chaplin, Josephine, Chapman, Graeme, Chapman, John, Chapman, Katie, Chapman, Laura, Chapman, Lianne, Chapman, Polly, Chapman, Timothy, Chappell, Lucy C, Chappell, Lucy, Charalambou, Amanda, Charles, Bethan, Charlton, Dianne, Chatar, Kevin, Chatha, Calvin, Chaube, Ritesh, Chaudhary, Muhammad Y N, Chaudhry, Iram, Chaudhuri, Nazia, Chaudhury, Muhammad, Chauhan, Anoop, Chauhan, Ruchi Singh, Chavasse, Nicola, Chawla, Vipal, Cheater, Lindsay, Cheaveau, James, Cheeld, Charlotte, Cheeseman, Michelle, Chen, Fang, Chen, Hui Min, Chen, Terence, Cheng, Floria, Cheng, Lok Yin, Cheng, Zhihang, Chenoweth, Helen, Cheong, Chun How, Cherian, Shiney, Cherrie, Mary, Cheshire, Helen, Cheung, Chee Kay, Cheung, Elaine, Cheung, Michelle, Cheyne, Claire, Chhabra, Swati, Chia, Wei Ling, Chiang, Eric, Chiapparino, Angela, Chicano, Rosavic, Chikwanha, Zviedzo A, Chilcott, Sam, Chimbo, Phillipa, Chin, KokWai, Chin, Wen Jie, Chineka, Rumbidzai, Chingale, Amol, Chisem, Heather, Chisenga, Claire, Chisnall, Ben, Chiswick, Carolyn, Chita, Sunder, Chitalia, Nihil, Chiu, Matthew, Chivima, Brenda, Chmiel, Catherine, Choi, Soha, Choon Kon Yune, Willy, Choudhary, Vandana, Choudhury, Sarah, Chow, Bing-Lun, Chowdhury, Mahibbur, Chowdhury, Shahid, Christenssen, Victoria, Christian, Peter, Christides, Alexander, Christie, Fiona, Christmas, Daniel, Christopherson, Thereza, Christy, Mark, Chrysostomou, Paris, Chua, Yunli, Chudgar, Dip, Chudleigh, Richard, Chukkambotla, Srikanth, Chukwu, Michael Eze, Chukwulobelu, Izu, Chung, Chi Yee, Church, Elaine, Church, Sara R, Churchill, David, Cianci, Nicole, Ciccone, Nick, Cicconi, Paola, Cinardo, Paola, Cipinova, Zdenka, Cipriano, Bessie, Clamp, Sarah, Clapham, Melanie, Clare, Edel, Clare, Sarbjit, Clark, Andrew, Clark, Charlotte, Clark, Diane, Clark, Felicity, Clark, Gabrielle, Clark, James, Clark, Katherine, Clark, Kaylea, Clark, Louise, Clark, Lucy, Clark, Matthew, Clark, Patricia, Clark, Richard, Clark, Thomas, Clark, Zoe, Clarke, Andrea, Clarke, Paul, Clarke, Robert, Clarke, Roseanne, Clarke, Samantha, Clarke, Sheron, Claxton, Alleyna, Clay, Kate, Clayton, Elizabeth, Clayton, Olivia, Clayton-Smith, Jill, Cleaver, Chris, Clemente de la Torre, Carlota, Clements, Jayne, Clements, Suzanne, Clemons, Francesca, Clifford, Rachael, Clifford, Sarah, Clive, Amelia, Clouston, Jonathan, Clueit, Samantha, Clyne, Andrea, Coakley, Michelle, Coakley, Peter G L, Cobain, Kathryn, Cochrane, Alexandra, Cochrane, Patricia, Cockerell, Maeve, Cockerill, Helen, Cocks, Shirley, Codling, Rachel, Coe, Adam, Coetzee, Samantha, Coey, David, Cohen, Danielle, Cohen, Jonathan, Cohen, Oliver, Cohen, David, Cohn, Mike, Coke, Louise, Coker, Olutoyin, Colbeck, Nicholas, Colbert, Roghan, Cole, Esther, Cole, Jade, Cole, Joby, Coleman, Garry, Coleman, Matt, Coleman, Tom, Coles, Holly, Colin, Macleod, Colino-Acevedo, Alicia, Colley, Julie, Collier, Dawn, Collier, Heather, Collini, Paul, Collins, Emma, Collins, Jaimie, Collins, Joanne, Collins, Nicola, Collins, Sally, Collins, Vicky, Collinson, Andrew, Collinson, Bernadette, Collinson, Jennifer, Collis, Matthew, Colmar, Madeleine, Colton, Hayley E, Colton, James, Colville, Katie, Colvin, Carolyn, Combes, Edward, Comer, David, Comerford, Alison, Concannon, Dónal, Condliffe, Robin, Connell, Lynne, Connell, Natalie, Connelly, Karen, Connolly, Gavin, Connor, Emma, Conroy, Antonia, Conteh, Veronica, Convery, Rory, Conway, Francesca, Conway, Grainne, Conway, Rhiannon, Conyngham, Jo-Anna, Cook, Colette, Cook, Eloise, Cook, Gemma, Cook, Helen, Cook, Julie, Cooke, Danielle, Cooke, Graham, Cooke, Katrina, Cooke, Tim, Cooper, Adele, Cooper, Chris, Cooper, David, Cooper, Helen, Cooper, Jamie, Cooper, Lauren, Cooper, Nick, Cooper, Rowena, Cope, Thomas, Corbet, Sinead, Corbett, Carolyn, Corcoran, John, Cordell, Chris, Cordle, Jessica, Corfield, Alasdair, Corless, John, Corlett, Alison, Cornwell, Joe, Cornwell, Michael, Corogeanu, Diana, Corredera, Mirella, Corrigan, Ruth, Corry, P, Corser, Rita, Cosgrove, Denise, Cosier, Tracey, Costa, Patricia, Coston, Charlie, Cotgrove, Susannah, Coton, Zoe, Cottam, Lisa-Jayne, Cotter, Rhiannon, Cotterill, Donna, Cotton, Caroline, Coull, Andrew, Coulson, James, Counsell, David, Counter, David, Coupland, Cherry, Courtney, Ellie, Courtney, Julia, Cousins, Rebecca, Cowan, Alexander, Cowan, Elena, Cowell, Richard, Cowen, Louise, Cowman, Steve, Cowton, Amanda, Cox, Ellie, Cox, Giles, Cox, Karina, Cox, Miriam, Coy, Karen, Cradduck-Bamford, Andrea, Craig, Victoria, Craighead, Felicity, Cramp, Matthew, Crause, Jacolene, Crawford, Angie, Crawford, Emma, Crawford, Isobel, Crawshaw, Sarah, Creagh-Brown, Ben, Creamer, Andrew, Cremona, Joanne, Cremona, Saveria, Cresswell, Janet, Cribb, Mark, Crichton, Charles, Crilly, Declan, Crisp, Lauren, Crisp, Nikki, Crocombe, Dominic, Croft, Maria, Crook, Derrick, Crooks, Jennifer, Crosby, Harriet, Cross, Elizabeth, Cross, Ellie, Cross, Sarah, Cross, Tim, Crothers, Amy, Crotty, Stephen, Crouch, Susan, Crow, Madeleine, Crowder, Amanda, Crowley, Kate, Crowley, Teresa, Croysdill, Rebecca, Cruickshank, Callum, Cruickshank, Conor, Cruickshank, Irena, Cruise, James, Cruz, Carina, Cruz Cervera, Trino, Cryans, Dominic, Cui, Guanguo, Cui, Helen, Cullen, Lorraine, Cummings-Fosong, Gillian, Cunliffe, Victoria, Cunningham, Neil, Cunningham, Nicola, Cupitt, Jason, Curgenven, Hollie, Curnow, Gerens, Curran, David, Curran, Simon, Currie, Craig, Currie, Jacqueline, Currie, Scarlett, Curtis, Jonathan, Curtis, Katrina, Curtis, Olivia, Curtis, Thomas, Cuthbertson, Rebecca, Cutler, Sean, Czekaj, Marta, Czylok, Patrycja, D'Arcangelo, Silvia, da Rocha, Joana, Dagens, Andrew, Daggett, Helen, Daglish, Jacqui, Dahiya, Sandeep, Dale, Anne, Dale, Katie, Dale, Michaela, Dale, Sam, Dales, Jolyon, Dalgleish, Helen, Dallow, Helen, Dalton, Dermot, Daly, Zoe, Damm, Eleanor, Danga, Akila, Daniel, Amelia, Daniel, Priya, Daniels, Allison, Dann, Adela, Danso-Bamfo, Sandra, Darbyshire, Alex, Darbyshire, Janet, Dargan, Paul, Dark, Paul, Darlington, Kate, Darnell, Sarah, Darton, Tom, Darylile, Guledew, Das, Manjusha, Das, Sukamal, Daschel, Martin, Dasgin, Joanne, Datta, Dibyendu, Daunt, Anna, Dave, Vaishali, Davenport, Emily, Davey, Mark, Davey, Miriam, Davey, Molly, David, Mini, Davidson, Alexander, Davidson, Laura, Davidson, Neil, Davidson, Richard, Davies, Albert, Davies, Amanda, Davies, Amy, Davies, Angela, Davies, Carolyn, Davies, Catrin, Davies, Drew, Davies, Elaine, Davies, Ffyon, Davies, Helen, Davies, Jim, Davies, Karen, Davies, Kelly, Davies, Kim, Davies, Louisa, Davies, Matthew, Davies, Michelle, Davies, Nina, Davies, Owen, Davies, Patrick, Davies, Rachel, Davies, Rhys, Davies, Ruth, Davies, Sarah, Davies, Simon, Davis, Alison, Davis, Gwyneth, Davis, Illinos, Davis, Julie-Ann, Davis, Katherine, Davis, Peter, Davison, Alexander, Dawe, Christine, Dawe, H, Dawkins, Mark, Dawson, Danielle, Dawson, Elizabeth, Dawson, Joy, Dawson, Susan, Dawson, Tom, Daxter, Andrew, Day, Andrew, Day, Jacob, Day, Jeremy N, D'Costa, Jamie, De, Parijat, de Fonseka, Duneesha, de Freitas, Toni, De Santana Miranda, Frederico, de Sausmarez, Eleanor, de Silva, Shanika, de Silva, Thushan, De Sousa, Jessica, De Sousa, Paulo, de Souza, James, De Soyza, Anthony, de Vere, Natasha, de Vos, Johannes, Deacon, Bethan, Dealing, Sharon, Dean, Anna, Dean, Julie, Dean, Katrina, Dean, Stephen, Dean, Tessa, Deane, Jill, Dear, James, Dearden, Effie, Deary, Alison, Deas, Catherine, Debbie, Samuel, Debreceni, Gabor, Deelchand, Vashist, Deeley, Matthew, Deery, Joanne, Defever, Emmanuel, Del Forno, Manuela, Dela Rosa, Arnold, Dell, Amanda, Demetriou, Carrie, DeMets, David, Democratis, Jane, Denham, Jacqueline, Denis, Emmanuelle, Denley, Laura, Denmade, Craig, Dent, Kathy, Dent, Martin, Denton, Elise, Denwood, Tom, Deole, Nishigandh, Depala, Darshita, Depante, Maria, Dermody, Susan, Desai, Amisha, Desai, Asmita, Desai, Purav, Deshpande, Sanjeev, Deshpande, Vai, Devkota, Sirjana, Devkota, Usha, Dey, Prakash, Dey, Vishal, Deylami, Rogin, Dhaliwal, Kevin, Dhani, Sundip, Dhanoa, Amandeep, Dhar, Mili, Dhasmana, Devesh, Dhillon, Ekanjali, Dhillon, Reiss, Dhimal, Meghnath, Dias, Priya, Diaz, Stephanie, Diaz-Pratt, Kayleigh, Dickerson, Debbie, Dicks, Pamela, Dickson, Stuart, Digby, J, Dillane, Sean, Diment, Sarah, Dimitri, Paul, Dinh, Thai Ha, Dipper, Alex, Dirmantaite, Laura, Ditchfield, Lisa, Diver, Sarah, Diwakar, Lavanya, Dixon, Caroline, Dixon, Giles, Djeugam, Brice, Dlouhy, Petr, D'Mello, Andrea, Dmitri, Paul, Dobbie, Laurence, Dobranszky Oroian, Marinela, Dobson, Charlotte, Dobson, Lee, Docherty, Marie, Dockrell, David, Dodd, James, Dodds, Jackie, Dodds, Rebecca, Dodds, Steve, Dogra, Richi, Doherty, Erin, Doherty, Warren, Doi, Yumiko, Doig, Iain, Doke, Eleanor, Dolan, Daniel, Dolman, Mark, Dolman, Rozzie, Donald, Lisa, Donaldson, Callum, Donaldson, Christopher, Donaldson, Denise, Donaldson, Gillian, Donaldson, Kate, Donnachie, Joanne, Donnelly, Eilish, Donnelly, Ronan, Donohoe, Aravindhan, Donohoe, Gemma, Donohue, Bryan, Donton, Sinead, Dooks, Emma, Doran, Grainne, Dorey, Kane, Dorgan, Sharon, Dosani, Moonira, Dosanjh, Davinder, Dospinescu, Paula, Douglas, Katie, Douse, Jonathan, Dowden, Lucy, Dower, Michelle, Dowling, Sud, Downer, Nicola, Downes, Charlotte, Downes, Rob, Downes, Thomas, Downey, Damian, Downey, Robert, Downs, Louise, Dowson, Simon, Dragan, Cornel, Dragos, Cristina, Drain, Maire, Drake, Chelsea, Drew, Victoria, Drewett, Olivia, Driscoll, Celine, Drogan, Helena, Drummond, Graham, Drury, Katie, Druyeh, Ronald, Dryburgh-Jones, Jack, Drysdale, Simon, Du Thinh, An, Dube, Hazel, Dube, Judith, Duberley, Stephen, Duckles-Leech, Hayley, Duff, Nicola, Duffield, Emma, Duffy, Helen, Dufour, Lionel, Duggan, Annette, Dugh, Parveen, Duignan, Janice, Dummer, Simon, Duncan, Andrew, Duncan, Christopher, Duncan, Fullerton, Duncan, Gregory, Dundas, Stephanie, Dunn, Alessia, Dunn, Charlotte, Dunn, Damian, Dunn, Laura, Dunn, Paul, Dunne, Charlene, Dunne, Karen, Dunning, Fiona, Dunphy, Aidan, Duraiswamy, Venkat, Duran, Beatriz, DuRand, Ingrid, Duric, Natalie, Durie, Alison, Durie, Emily, Durrington, Hannah, Duvnjak, Haris, Dwarakanath, Akshay, Dwarakanath, Laasya, Dwyer, Ellen, Dyball, Claudia, Dyer, Kristyn, Dymond, Harvey, Dymond, Tom, Eades, Chris, Eagles, Laura, Early, Joanne, Earwaker, Melissa, Easom, Nicholas, East, Clare, Easthope, Amy, Easton, Fraser, Eatough, Ruth, Ebigbola, Oluwadamilola, Ebner, Daniel, Ebon, Martin, Eccles, Sinan, Eddings, Chloe, Eddleston, Michael, Edgar, Maureen, Edgerley, Katharine, Edmond, Nicholas, Edmondson, Mary, Edmunds, Tracy, Edwards, Alexandra, Edwards, Catherine, Edwards, Joy, Edwards, Kennedy, Edwards, Mandy, Eedle, Jenny, Egginton, Dawn, Ehiorobo, Loveth, Eisen, Sarah, Ekeowa, Ugochukwu, Ekoi, Mohamed, Ekunola, Ayomide, El Behery, Soha, Elbeshy, Mohamed, El-Bouzidi, Kate, Elder, Jennifer, El-Din, Mohammed, Eleanor, Diana, Eletu, Ibrahim, Elfar, Eman, Elgamal, Mayy M, Elgohary, Amr, Elia, Stellios, Elias, Jennifer, Elias, Tania, Elkaram, Nadia, Elkins, Andrew V, Ellam, Julie, Ellard, Nikki, Ellerton, Laura N, Elliot, Lucy, Elliott, Amy, Elliott, Fiona, Elliott, Kerry, Elliott, Scott, Ellis, Annie, Ellis, Christine, Ellis, Kaytie, Ellis, Tak-Yan, Ellis, Yvette, Elmahdi, Rahma, Elmahi, Einas, Elmasry, Hannah-May, Elndari, Najla, Elneima, Omer, Elokl, Mohamed, Elradi, Ahmed, Elsaadany, Mohamed, El-Sayeh, Sally, El-Sbahi, Hana, Elsefi, Tarek, El-Shakankery, Karim, El-Taweel, Hosni, Elyoussfi, Sarah, Emberey, Jonathan, Emberson, Jonathan R, Emberton, John, Emmanuel, Julian, Emmerson, Ingrid, Emms, Michael, Emond, Florence, Emonts, Marieke, Enachi, Nicu, Engden, Angila, English, Katy, Entwistle, Emma, Enyi, Hene, Erotocritou, Marios, Eskander, Peter, Esmail, Hanif, Estcourt, Lise, Evans, Brynach, Evans, Chris, Evans, Debra, Evans, Gail, Evans, Gareth, Evans, Jennifer, Evans, Jolanta, Evans, Lisa, Evans, Lynn, Evans, Mim, Evans, Morgan, Evans, Ranoromanana, Evans, Teriann, Evans, Terry J, Everden, Caroline, Everden, Serenydd, Evison, Hayley, Evison, Lynsey, Eyre, David, Faccenda, Jacqueline, Fahel, Leila, Fahmay, Youstina, Fairbairn, Sara, Fairbairn, Terry, Fairclough, Andy, Fairlie, Louise, Fairweather, Mark, Fajardo, Anne, Falcone, Naomi, Falconer, Euan, Fallon, John, Fallow, Andrea, Faluyi, David, Fancois, Victoria, Farah, Qayyum, Fard, Nowin Z, Fares, Leila, Farg, Amr, Farmer, Adam, Farmer, Katie, Farmery, Toni, Farnworth, Samantha, Farook, Faiyaz, Farooq, Hadia, Farooq, Sidrah, Farquhar, Fiona, Farrell, Aaron, Farrell, Barbara, Farthing, James, Farzana, Syeda, Fasina, Rahmatu, Fatemi, Azam, Fatemi, Mina, Fatimah, Nibah, Faulkner, Maria, Faust, Saul N, Fawke, Joe, Fawohunre, Sinmidele, Fazal, Abul, Fearby, Simon, Feben, Alex, Fedel, Federico, Fedorova, Daria, Fegan, Christopher, Felongco, Mae, Felton, Lynsey, Felton, Tim, Fenlon, Kate, Fenn, Andrea, Fenner, Isabelle, Fenton, Ciara, Fenton, Melisa, Ferguson, Cameron, Ferguson, Jenny, Ferguson, Kathryn, Ferguson, Katie, Ferguson, Susan, Ferguson, Susie, Ferguson, Victoria, Fernandes, Denzil, Fernandez, Candida, Fernandez, Eduardo, Fernandez, Maria, Fernandez Lopez, Sonia, Fernando, Callum J, Feroz, Ahmed, Ferranti, Pietro, Ferrari, Thais, Ferrelly, Eleanor, Ferrera, Alexandra, Ferriman, Emma, Fethers, Nicholas, Field, Ben, Field, Janet, Field, Rebecca, Fielder, Karen, Fieldhouse, Lindsey, Fielding, Andra, Fielding, Julie, Fielding, Sarah, Fikree, Asma, Filson, Sarah A, Finbow, Sarah, Finch, Debbie, Finch, Joanne, Finch, Laurie, Fineman, Natalie, Finlayson, Lauren, Finn, Adam, Finn, Joanne, Finney, Clare, Fiouni, Sofia, Fiquet, Jo, Fisher, James, Fisher, Neil, Fishman, Daniel, Fishwick, Krystofer, Fitzgerald, Fiona, Fitzpatrick-Creamer, Chloe, Flaherty, Jan, Flanagan, Michael, Flanders, Charles, Fleming, Julie, Fleming, Lucy, Fleming, Paul, Flesher, William, Fletcher, Alison, Fletcher, Jonathan, Fletcher, Lucy, Fletcher, Simon, Fletcher, Sophie, Flewitt, Karen, Flood, Christopher, Floodgate, Ian, Florence, Vincent, Floyd, Sharon, Flynn, Rachel, Foden, Claire, Fofana, Adama, Fogarty, Georgina, Foley, Claire, Foley, Paul, Folkes, Linda, Font, Daniela M, Foo, Aiwyne, Foo, Jane, Foot, Andrew, Foot, Jayne, Forbes, Jane, Ford, Jamie, Foreman, Jennifer, Fornolles, Caroline, Forrest, Adam, Forsey, Ellie, Forsey, Miranda, Forshall, Thomas, Forster, Elliot, Forton, Julian, Foster, Emily, Foster, Joseph, Foster, Rachel A, Foster, Tracy, Foulds, Angela, Foulds, Ian, Fowe, Folakemi, Fowler, Emily, Fowler, Robert, Fowler, Stephen, Fox, Claire, Fox, Heather, Fox, Jonathan, Fox, Lauren, Fox, Natalie, Fox, Olivia, Fox, Simon, Foxton, Sarah-Jane, Frake, Rebecca, Francioni, Alex, Francis, Olesya, Francis, Rebecca, Francis, Sarah, Francis, Sasha, Francis-Bacon, Theodora, Frankland, Helen, Franklin, Jessica, Fraser, Catherine, Frayling, Sharon, Fredlund, Martyn, Freeman, Carol, Freeman, Elaine, Freeman, Hannah, Freeman, Nicola, Freer, Clare, French, Eleanor, Frise, Matthew, Fromson, Renate, Frosh, Adam, Frost, John, Frost, Victoria, Froud, Oliver, Frowd, Rachel, Fryatt, Arun, Fuller, Bridget, Fuller, Liz, Fuller, Tracy, Fullerton, Duncan, Fung, Carrie, Fung, Gayle, Funnell, Sarah, Furness, John, Fyfe, Andrew, G, Nytianandan, Gabbitas, Elizabeth, Gabriel, Claire, Gabriel, Zoë, Gachi, Hadiza, Gahir, Joshua, Gajebasia, Sarveen, Gajewska-Knapik, Katarzyna, Gale, Christopher, Gale, Hugo, Gale, Rebecca, Gali, Swetha, Gallagher, Bernadette, Gallagher, Jude, Gallagher, Rosie, Gallagher, William, Galliford, Joanne, Galloway, Catherine, Galloway, Chris, Galloway, Emma, Galloway, Jacqui, Galloway, James, Gamble, Laura, Gamble, Liz, Gammon, Brian, Ganapathi, Jaikumar, Ganapathy, Ramesh, Gandhi, Kaminiben, Gandhi, Sarah, Ganesh, Usha, Gani, Abrar, Garden, Emma-James, Gardener, Antoni D, Gardiner, Emma, Gardiner, Michael, Gardiner, Phil, Gardiner, Siobhan, Gardiner-Hill, Caroline, Gardner, Jonathan, Garfield, Mark, Garg, Atul, Garlick, Nathan, Garner, Justin, Garner, Lucie, Garner, Zoe, Garr, Rosaline, Garty, Florence, Gascoyne, Rachel, Gashau, Hyeriju, Gatenby, Aoife, Gaughan, Erin, Gaurav, Alok, Gavrila, Mariana, Gaylard, Jane, Gaywood, Emma, Geddie, Catherine, Gedge, Ian, Gee, Sarah, Gellamucho, Minerva, Gelly, Karzan, Gelmon, Leila, Gelves-Zapata, Sandra, Genato, Gemma, Gent, Susan, Geoghegan, Natalie, George, Sam, George, Tina, Georges, Simon, Georgiou, Domonique, Gerard, Peter, Gerdes, Leigh, Germain, Louise, Gerrish, Helen, Getachew, Abel, Gethin, Louise, Ghanayem, Hisham, Gherman, Anca, Ghosh, Alison, Ghosh, Justin, Ghosh, Sudhamay, Giannopoulou, Sarra, Gibani, Malick, Gibbison, Ben, Gibbons, Kerry, Gibson, Alex, Gibson, Bethan, Gibson, Kimberley, Gibson, Kirsty, Gibson, Sian, Gilbert, Cat, Gilbert, Jeanette, Gilbert, Kayleigh, Giles, Benjamin, Gill, Mandy, Gill, Lynne, Gillen, Paul, Gillesen, Annelies, Gillespie, Katherine, Gillham, Elizabeth, Gillian, Andrew, Gilliland, Deborah, Gillott, Robert, Gilmour, Danielle, Gilmour, Kate, Ginting, Franciscus, Giokanini-Royal, Theodora, Gipson, Anna, Girling, Joanna, Gisby, Rhian, Gkioni, Angelena, Gkoritsa, Aikaterini, Gkrania-Klotsas, Effrossyni, Gladwell, Amy, Glanville, James, Glasgow, Jessica, Glasgow, Susannah, Glass, Jon, Glass, Lynn, Glaysher, Sharon, Gledhill, Lisa, Glennon, Ana, Glover, John, Glover, Kyle, Glover Bengtsson, Jan, Glowski, Deborah, Gnanalingam, Chevanthy, Goddard, Julie, Goddard, Wendy, Godden, Emily, Godden, Jo, Godson, Emma, Gogoi, Sukanya, Goh, Aiky, Goiriz, Rebeca, Gokaraju, Sriya, Goldacre, Raphael, Goldsmith, Arthur, Goldsmith, Portia, Gomersall, Darren, Gomez, Lucia, Gomez-Marcos, Raquel, Gondal, Ali, Gonzalez, Celia, Goodall, Jack, Goodenough, Bob, Goodfellow, Laura, Goodlife, James, Goodwin, Camelia, Goodwin, Elizabeth, Goodwin, Jayne, Goodyear, Paula, Gooentilleke, Rajiv, Goonasekara, Michelle, Gooseman, Sheila, Gopal, Shameer, Gordon, Sally, Gore, Robin, Gorick, Hugh, Gorman, Caitlin, Gorman, Claire, Gormely, Stuart, Gorog, Diana, Gorst, Michelle, Gorsuch, Thomas, Gosai, Jayshreebahen, Gosling, Rebecca, Gosling, Sally, Gosney, Georgina, Goss, Vanessa, Gotham, Dzintars, Gott, Naomi, Goudie, Elizabeth, Gould, Susan, Gourbault, Lysander, Govind, Abha, Gowans, Sharon, Gowda, Girish, Gowda, Rohit, Gower, Hannah, Goyal, Pankaj, Goyal, Sunil, Goyal, Sushant, Graham, Clive, Graham, Jonathan, Graham, Justin, Graham, Libby, Graham, Sharon, Graham-Brown, Matthew, Grahamslaw, Julia, Grana, Gianluca, Grandison, Tracyanne, Grandjean, Louis, Grant, Alison, Grant, Ann, Grant, David, Grant, Matthew, Grant, Pauleen, Gravell, Rhys, Graves, Jenny, Gray, Alasdair, Gray, Catherine, Gray, Georgina, Gray, Jackie, Gray, Karen, Gray, Nicola, Gray, Sebastian, Grayson, Alan, Greaves, Fiona, Greaves, Paul, Green, Alastair, Green, Charlotte, Green, Christopher A, Green, David, Green, Frederick, Green, Joel, Green, Marie, Green, Nicola, Green, Stacey, Greene, Diarra, Greenfield, Philippa, Greenhalgh, Alan, Greenwood, Daniel, Greer, Sandra, Gregory, James, Gregory, Jane, Gregory, Katie, Gregory, Tamsin, Greig, Jill, Greig, Julia, Grenfell, Rebecca, Grenier, Teena, Grevatt, Susan, Grey, Glaxy, Gribbin, Andrew, Gribble, Amy, Grieg, Natasha, Grieve, Douglas, Griffin, Ben, Griffin, Denise, Griffin, Mel, Griffith, Sian, Griffiths, Andrew, Griffiths, Daniel, Griffiths, David, Griffiths, Donna, Griffiths, Isabel, Griffiths, Mark, Griffiths, Nicola, Griffiths, Oliver, Griffiths, Sarah, Griffiths, Yvonne, Grigoriadou, Sofia, Grigsby, Steph, Grobovaite, Evelina, Grondin, Clarissa, Groome, Rachel, Grosu, Liliana, Grounds, Jenny, Grout, Margaret, Grover, Helen, Grover, Helen, Groves, Jayne, Grubb, Neil, Grundy, Julie, Guarino, Francesca, Gudur, Sharada, Guettari, Sharazeq, Gulati, Shivang, Gulia, Vikas, Gunasekera, Pumali, Gunawardena, Malin, Gunganah, Kirun, Gunn, Jessica, Gunter, Emma, Gupta, Alok, Gupta, Atul, Gupta, Rajeev, Gupta, Richa, Gupta, Rishi, Gupta, Tarun, Gupta, Vineet, Gupta-Wright, Ankur, Guratsky, Victoria, Gureviciute, Alvyda, Gurram, Sambasivarao, Gurung, Anju, Gurung, Bhawana, Gurung, Shraddha, Guth, Hazel, Gyanwali, Pradip, Habibi, Ruth, Hack, Berkin, Hackney, Pamela, Hacon, Christian, Haddad, Aiman, Hadfield, Denise, Hadjiandreou, Michalis, Hadjisavvas, Nikolaos, Haestier, Anna, Hafiz, Nauman, Hafiz-Ur-Rehman, Rana, Hafsa, Javed, Hagan, Samantha, Hague, Jack W, Hague, Rosemary, Haigh, Kate, Haines, Christina, Hainey, Scott, Hair, Morton, Hairsine, Brigid, Hajnik, Juraj, Haldeos, Anne, Halder, Writaja, Hale, Jennie, Halevy, Carmel, Halford, Paul, Halford, William, Hall, Alistair, Hall, Anthony, Hall, Claire, Hall, Elizabeth, Hall, Fiona, Hall, Helen, Hall, Jennifer, Hall, Kathryn, Hallas, Jan, Hallas, Kyle, Hallett, Charles, Halls, Heather, Hamdollah-Zadeh, Maryam, Hameed, Bilal, Hamers, Raph, Hamid, Imran, Hamie, Mohamad, Hamilton, Bethany, Hamilton, Fergus, Hamilton, Leigh, Hamilton, Nicola, Hamilton, Sara, Hamlin, Ruth, Hamlyn, Eleanor, Hammans, Beatrice, Hammersley, Shirley, Hammerton, Kate, Hammond, Bev, Hammond, Leah, Hammonds, Fiona, Hamoodi, Ibrahim, Hampshire, Karen, Hampson, Jude, Hampson, Lucy, Hanci, Ozan, Hand, Sadiyah, Handford, Jasmine, Handrean, Soran, Haney, Sarah, Hanif, Sheharyar, Hanison, E, Hanison, Esther, Hannah, Jennifer, Hannington, Amy, Hannun, Merhej, Hanrath, Aidan, Hanson, Anita, Hanson, Jane, Hanson, Kathryn, Hanson, Steve, Haq, Mazhar Ul, Haqiqi, Ala, Haque, Monjurul, Harden, Lesley, Harding, Zoe, Hardman, Simon, Hardy, Joanna, Haresh, Kumar, Harford, Rachel, Hargadon, Beverley, Hargreaves, Carolyn, Hargreaves, James, Harin, Alice, Haris, Mohammed, Harlock, Edward, Harman, Paula, Harman, Tracy, Harmer, Mark, Haroon, Muhammad A, Harper, Charlie, Harper, Heather, Harper, Peter, Harper, Rosemary, Harrhy, Sarah, Harrington, Sian, Harrington-Davies, Yasmin, Harris, Jade, Harris, Jess, Harris, John, Harris, Laura, Harris, Marie-Clare, Harris, Nichola, Harris, Sophie, Harrison, David, Harrison, Laura, Harrison, Melanie, Harrison, Rowan, Harrison, Susie, Harrison, Thomas, Harrison, Wendy, Harrod, Elizabeth, Hart, Ciaran, Hart, Dominic, Hartley, Lisa, Hartley, Rosemary, Hartley, Ruth, Hartley, Tom, Hartrey, William, Hartridge, Phillipa, Hartshorn, Stuart, Harvala, Heli, Harvey, Alice, Harvey, Angela, Harvey, Max, Harwood, Catherine, Harwood, Helen, Haselden, Brigitte, Hashem, K, Hashimm, Mohammed, Hashimoto, Tadaaki, Hashmi, Imranullah, Haslam, Zena, Hassan, Adil, Hassan, Ali, Hassasing, Sapna, Hassell, Jane, Hassell, Philip, Hastings, Alex, Hastings, Bethany, Hastings, Janice, Hatch, Stephanie, Hatton, Jonathan, Havinden-Williams, May, Havlik, Stefan, Hawcutt, Daniel B, Hawes, Kadean, Hawes, Liz, Hawes, Nicola, Hawkins, Annie, Hawkins, Nancy, Hawley, Dan, Hawley-Jones, Ed, Haworth, Edward, Hay, Alasdair, Hay, Cathy, Hayat, Amna, Hayat, Jamal, Hayathu, Mohamed-Riyal, Hayder, A, Hayes, Anne, Hayes, Jonas, Hayes, Kate, Hayes, Melony, Hayes, Fiona, Hayle, Patrick, Haylett, Chloe, Hayman, Antara, Hayman, Melanie, Haynes, Matthew, Haynes, Richard, Hayre, Rachel, Haysom, Sarah, Hayward, James, Haywood, Patrick, Hazelton, Tracy, Hazenberg, Phoebe, He, Zhengmai, Headon, Elizabeth, Heal, Carrie, Healy, Brendan, Hearn, Amy, Heath, Angela, Heath, Rowan, Heaton, Diane, Hebbron, Kerry, Hector, Gemma, Hedges, Andy, Hedges, Katrine, Heeley, Cheryl, Heeney, Elaine, Heire, Rajdeep, Hemingway, Georgia, Hemmila, Ulla, Hemphill, Scott, Hemsley, Deborah, Henderson, Abigail, Henderson, Eilidh, Henderson, Jennifer, Henderson, Steven, Henry, Joanne, Henry, Karol, Henry, Lavinia, Henry, Margo, Henry, Natalie, Henshall, David, Herdman, Gillian, Herdman-Grant, Rosaleen, Herkes, Morag, Heron, Emma, Herrington, William, Heselden, Emilia, Heslop, Peta, Hester, Simon, Hetherington, Emily, Hetherington, Joseph, Hettiarachchi, Chamila, Hettiarachchi, Pramodh, Hewer, Hayley, Hewertson, John, Hewetson, Anna, Hewins, Sue, Hewitt, Claire, Hewitt, Davina, Hewitt, Richard, Hewson, Jacqueline, Hey, Samuel, Heyderman, Robert S, Heydtmann, Mathis, Heys, Joseph, Heywood, Jonathan, Hibbert, Meg, Hickey, John, Hickey, Naomi, Hickey, Peter, Hicks, Alex, Hicks, Bethany, Hicks, Jenny, Hicks, Scott R, Higbee, Daniel, Higgins, Lucy, Higham, Andrew, Highcock, Martin, Highgate, Judith, Hikmat, Mondy, Hill, Amanda, Hill, Helen, Hill, Joanne, Hill, Lisa, Hill, Phoebe, Hill, Uta, Hilldrith, Annette, Hillman-Cooper, Catherine, Hilton, Zoe, Hinch, Sarah, Hindle, Andrew, Hindmarsh, Alice, Hine, Paul, Hinshaw, Kim, Hird, Clare, Hives, Jemma, Ho, Benson, Hoare, Michaela, Hobden, David, Hobden, Gill, Hobrok, Maria, Hobson, Simon, Hodge, Simon, Hodgen, Lesley, Hodgkins, Holly, Hodgkinson, Sally, Hodgson, David, Hodgson, Helen, Hodgson, Luke, Hodgson, Sheila, Hodkinson, Gemma, Hodson, Kenneth, Hogben, Matthew, Hogg, Lucy, Hoggett, Lee, Holborow, Abigail, Holbrook, Catherine, Holden, Catherine, Holden, Melinda, Holder, Thomas, Holdhof, Niels, Holdsworth, Hannah, Holland, Lisa, Holland, Nicky, Hollands, Marie, Holliday, Elizabeth, Holling, Nina, Hollos, Laszlo, Holloway, Simon, Hollyer, Marcus, Holman, Amy, Holmes, Ann, Holmes, Megan, Holmes, Raphael, Holmes, Rebecca, Holroyd, Kelly, Holt, Lyndsey, Holt, Siobhan, Holt, Susie, Holyome, Alexandra, Home, Marie, Homewood, Renate, Hong, Kate, Hooper, Clare, Hoosdally, Sarah, Hope, Samantha, Hope, Susan, Hopkins, Bridget, Horby, Peter W, Horler, Stephanie, Hormis, Anil, Hornan, Daniel, Hornby, Nicola, Horne, Zoey, Horner, Rebecca, Horsford, Latoya, Horsford, Megan, Horsford, Mark, Horsham, Valana, Horsley, Alexander, Horsley, Ashley, Horsley, Elizabeth, Horton, Sarah, Hosea, Jane, Hoskins, Toby, Hossain, Muhammad S, Hossain, Rashed, Hough, Maxine, Hough, Sarah, Houghton, Catherine, Houghton, Kathryn, Houlihan, Rebecca, Housely, Kay, Houston, Hamish, Hovvels, Roseanna, How, Lee, Howaniec, Laura, Howard, Laura, Howard, Linda, Howard, Lucy, Howard, Sarah, Howard, Stuart, Howard-Griffin, Richard, Howarth, Alison, Howe, Serena, Howells, Mark, Howie, Lyn, Howlett, Kerry, Howlett, Sophie, Hrycaiczuk, Josh, Htoon, Naing Zaya, Htwe, Su, Hu, Ying, Huah, Chiang Ooi, Huckle, Abby, Huda, Shahzya, Hudak, Alison, Hudig, Lisa, Hudson, Heather, Hudson, Oli, Hufton, Alison, Huggins, Connor, Hughes, Alistair, Hughes, Emma, Hughes, Gareth, Hughes, Heather, Hughes, Luke, Hughes, Rachel, Hughes, Rebecca, Hughes, Samantha, Hughes, Stephen, Hughes, Vikki, Hughes, Wesley, Huhn, Lukas, Hui, Ching, Hulbert, Ruth, Hull, Diana, Hull, Grace, Hull, Robert, Hulme, Amanda, Hulme, Peter, Hulse, Wendy, Hulston, George, Hum, Ryan, Hume, Megan, Humphrey, Charlotte, Humphries, Alasdair, Humphries, Joanne, Hunt, Fiona, Hunt, Jonquil, Hunt, Kristen, Hunt, Luke, Hunt, Sophie, Hunter, Alexandra, Hunter, Ewan, Hunter, Karl, Hunter, Neil, Hunter, Sophie, Huntington, George, Hurditch, Elizabeth, Hurley, Cian, Hurley, Katrina, Husain, Mohammed A, Husaini, Syeda Y, Huson, Coralie, Hussain, Afreen, Hussain, Ibraar, Hussain, Ifza, Hussain, Mohammad, Hussain, Muhammad, Hussain, Reda, Hussain, Samia, Hussain, Sanniah, Hussain, Yasmin, Hussam El-Din, Mohammed, Hussey, Rebecca, Hussien, Adiel H, Hutchinson, Anja, Hutchinson, Camille, Hutchinson, Dorothy, Hutchinson, Elizabeth, Hutchinson, John, Hutsby, Claire, Hutton, Paula, Huyen, Thuong, Hydes, Daniella, Hyde-Wyatt, Jamie, Hynes, Niamh, Hyslop, Megan, Ibraheim, Mazen, Ibrahim, Abdalla, Ibrahim, Ahmed, Ibrahim, Asil, Ibrahim, Mohamed, Ibrahim, Wadah, Idowu, Adetokunbo I, Idrees, Muhammad, Idrees, Nauman, Iftikhar, Hina, Iftikhar, Mawara, Igwe, Chukwuemeka, Ijaz, Mohammad, Ikomi, Amaju, Iles, Clare, Iliodromiti, Stamatina, Ilsley, Mary, Ilves, Lorna, Imam-Gutierrez, La'ali, Imray, Christopher, Imtiaz, Haider, Ingham, Jack, Ingham, Julie, Ingham, Rory, Ingle, Tejas, Inglis, Jennifer, Ingram, Anne, Ingram, Luke, Inns, Peter, Inweregbu, Ken, Ionescu, Andreea A, Ionita, Ana, Iordanov, Ilian P, Ipe, Anil, Iqbal, Madiha, Iqbal, Mohammed, Iqbal Sait, Faisal, Ireland, Jane, Irons, Robert, Irshad, Mohannad, Irshad, Muhammad S, Irvine, Janice, Irvine, Val, Irving, Robert, Ishak, Mina, Isherwood, Erica, Islam, Aminul, Islam, Samsul, Islim, Abdurrahman, Ismail, Ali, Ismail, Omar, Ison, Caroline, Israa, M'hamedi, Isralls, Sharon, Ivan, Monica, Ivenso, Chineze, Ivy, Ashleigh, Iwanikiw, Sophie, Ixer, Karen, Iyer, Menaka, Iyer, Mia, Jack, Calum, Jackson, Amanda, Jackson, Ben, Jackson, Beth, Jackson, Ella, Jackson, Helen, Jackson, Lauren, Jackson, Melanie, Jackson, Nicola, Jackson, Shane, Jacob, Patricia, Jacob, Reni, Jacques, Nicola, Jafar, Anisa, Jafferji, Daniel, Jaffery, Ali, Jagadish, Chandrashekar, Jagannathan, Vijay, Jagpal, Mandeep, Jaime, Fernandez R, Jain, Neemisha, Jain, Seema, Jain, Susan, Jaiswal, Sanjay, Jajbhay, Danyal, Jaki, Thomas, Jallow, Bintou, Jaly, Yusuf, Jamal, Sabine, Jamal, Zeba, Jameel, Yasmin, James, Albie, James, Christie, James, Kate, James, Lee, James, Linda, James, Mark, James, Nicholas, James, Olivia, James, Rebecca, James, Ruth, James, Tracy, Jameson, Jack, Jamison, Aaron, Jane, Phoebe, Janmohamed, Azara, Japp, Deepa, Jardim, Victor, Jardine, Catherine, Jarnell, Emma, Jarvie, Ellie, Jarvis, Claire, Jarvis, Rosina, Jastrzebska, Patrycja, Javed, Hafsa, Jawad, Mays, Jawaheer, Lona, Jayachandran, Anu, Jayachandran, D, Jayakumar, Angelina, Jayaram, Deepak, Jayaram, Ravi, Jayasekera, Geeshath, Jayatilleke, Thilina, Jayebalan, Abi, Jeddi, Saman, Jeelani, Mohammad S, Jeffery, Katie, Jeffrey, Helen, Jeffrey, Rachel, Jeffreys, Nathan, Jeffs, Benjamin, Jegede, Debbie, Jemima, Taylor, Jenkin, Ifan, Jenkins, Alison, Jenkins, Christopher, Jenkins, David, Jenkins, Elinor, Jenkins, Sarah, Jenkins, Sian, Jenkins, Stephen, Jennings, Jacqui, Jennings, Louise, Jennings, Virginia, Jerome, Ellen, Jerry, Douglas, Jessup-Dunton, Ellen, Jesus Silva, Jorge A, Jetha, Champa, Jethwa, Kishan, Jha, Roshan, Jhanji, Shaman, Jian, Khoo, Jiao, Zhixin, Jimenez, Laura, Jimenez Gil, Ana, Jith, Jithin, Joefield, Teishel, Johal, Navraj, Johannessen, Karine, Johari, Aisyah, John, Annie, John, Anu, John, Navin, Johns, Emma, Johns, Margaret, Johnson, Antoinette, Johnson, Emma, Johnson, Gillian, Johnson, Kathryn, Johnson, Katie, Johnson, Luke, Johnson, Mark, Johnson, Nelsonseelan, Johnson, Oliver, Johnston, Claire, Johnston, Janet, Johnston, Susan, Johnston, Victoria, Johnstone, Dawn, Johnstone, Ed, Johnstone, Janet, Joishy, Manohar, Jones, Adam, Jones, Alistair, Jones, Annabel, Jones, Ben, Jones, Bryony, Jones, Carys, Jones, Ceri, Jones, Charlotte, Jones, Christine E, Jones, Debra, Jones, Emily, Jones, Gareth, Jones, Geraldine, Jones, Jac, Jones, James, Jones, Jonathon, Jones, Julie, Jones, Kate E, Jones, Laura, Jones, Laura M, Jones, Louise, Jones, Mathew, Jones, Nicola, Jones, Paul, Jones, Rhianna, Jones, Ruth E, Jones, Samantha, Jones, Sophie, Jones, Stefanie, Jones, Steve, Jones, Taya, Jones, Tim, Jones, Tracey, Jonnalagadda, Ramya, Jordache, Rebecca, Jose, Sanal, Joseph, Anna, Joseph, P Aiden, Joseph, Rosane, Joseph, Sibet, Joshi, Dhaara, Joshi, Mehul, Joshi, Pratichi, Josiah, Benz, Joyce, Tiffany, Ju Wen Kwek, Adriel, Jude, Edward, Judge, Parminder, Juhl, Jessica, Jujjavarapu, Sirisha, Juniper, Mark, Juszczak, Edmund, Jyothish, Deepthi, Kabiru Dawa, Kasamu, Kacar, Mark, Kadam, Nikhil, Kakoullis, Gail, Kala Bhushan, Azad, Kalayi, Richard J K, Kaliannan Periyasami, Roobala, Kallistrou, Efthymia, Kalsoom, Seika, Kam, Elisa, Kamara, John, Kamath, Ajay, Kamath, Prakash, Kamath, Ravindra, Kamerkar, Siddharth A, Kametas, Nick, Kamfose, Musaiwale, Kane, Leia, Kankam, Osei, Kannan, Thogulava, Kant, Abhinav, Kapil, Vikas, Kapoor, Ritoo, Kapoor, Sonal, Kar, Sourjya, Kara, Janaka, Kark, Rona, Karkey, Abhilasha, Karunaratne, Nicholas, Kasianczuk, Natashja, Kasipandian, Vidya, Kassam, Rizwan, Kathirgamachelvam, Janarth, Katsande, Victoria, Kaul, Kulbinder, Kaur, Daljit, Kaur, Dervinder, Kaur, Jasmin, Kaur, Jaspreet, Kausar, Zunaira, Kawser, Mohammad A A, Kay, Andrea, Kay, Sarah, Kayappurathu, Jossy N, Kaye, Callum, Kazeem, Ahemd, Kearns, Rachel, Kearsley, Nichola, Keating, Joanne, Keating, John, Keating, Liza, Keddie-Gray, Elizabeth, Keegan, Breffni, Keenan, Natalie, Kefas, Jonathan, Kegg, Stephen, Keith, Laura, Keke, Uzoamaka, Kellett, Joanne, Kelly, Alison, Kelly, David, Kelly, Diane, Kelly, Dominic, Kelly, Emma, Kelly, Laura, Kelly, Martin, Kelly, Michael, Kelly, Rosalind, Kelly, Sinead, Kelly, Stephen, Kelly-Baxter, Mary, Keltos, Marketa, Kemp, Timothy, Kendall-Smith, Alexandra, Kennard, Sarah, Kennedy, Ann, Kennedy, James, Kennedy-Hay, Sophie, Kenny, Julia, Kent, Melanie, Keogan, Lynne, Keough, Alexander, Kerr, A, Kerr, Andrew, Kerrison, Caroline, Kerry, Anthony, Kerslake, Helen, Kerslake, Ian, Kerss, Helen, Keshet-Price, Jocelyn, Kestelyn, Evelyne, Keyte, Georgina, Khadar, Abdul, Khalid, Ali, Khalid, Muhammad U, Khalid, Syed, Khalil, Amir, Khalil, Asma, Khalil, Sijjad, Khan, Abubakar, Khan, Ali, Khan, Al-Imran, Khan, Arham, Khan, Asad, Khan, Aurangzeb, Khan, Burhan, Khan, Fatimah, Khan, Kausik, Khan, Malik A, Khan, Marria, Khan, Mehrunnisha, Khan, Mohammad, Khan, Nayeem, Khan, Omar, Khan, Rahila, Khan, Shabana, Khan, Shahul, Khan, Shoaib, Khan, Tasaduksultan, Khan, Waseem, Khatana, Usman F, Khatri, Jibran, Khatri, Jyoti, Khatun, Hafiza, Khatun, Taslima, Kheia, Mena, Khera, Jacyntha, Khin, Htet Htet Ei, Khoja, Najaf, Khokhar, Kiran, Khurana, Chloe, Kibutu, Faith, Kidd, Andrew, Kidd, Michelle, Kidney, Joe, Kidney, Shane, Kieffer, Will, Kilbane, James, Kilby, Caroline, Kilich, Eliz, Killen, Eileen, Kilroy, Susan, Kim, Bomee, Kim, Jee W, Kimber, Sarah, King, Andy, King, Barbara, King, J, King, Jennifer, King, Kirsten, King, Rachel, King, Sarah, King, Victoria, King-Oakley, Emily, Kingsmore, Laura, Kinney, Fiona, Kiran, Sidra, Kirk, Jeremy, Kirk, Jodie, Kirkby, Amy, Kirkham, Emily, Kirkman, Gemma, Kirwan, Ursula, Kitching, Toby, Kitto, Laura, Kittridge, Lauren, Klaczek, Sarah, Kleemann, Frieder, Kmachia, Susan, Knapp, Christopher P, Knibbs, Lucy, Knight, Alicia, Knight, Fraser, Knight, Marian, Knight, Sarah, Knight, Steven, Knight, Tom, Knights, Ellen, Knights, Jane, Knolle, Martin, Knott, Carol, Knowles, Charlotte, Knowles, Karen, Knowles, Laurence, Knox, Emily, Knox, Lucy, Koch, Oliver, Kodituwakku, Ronan, Koduri, Gouri, Koirata, Aisha, Kolakaluri, Eirene, Kolodziej, Magdalena, Kolokouri, Eirini, Kon, Samantha, Konar, Niladri, Kononen, Mari, Konstantinidis, Athanasios, Koo, Hui Fen, Koopmans, Imogen, Kopyj, Emmanuela, Korcierz, Laura, Korolewicz, James, Koshy, George, Kosmidis, Chris, Kotecha, Jalpa, Kothandaraman, Easwari, Koukouflis, Leonidas, Kouranloo, Koushan, Kousar, Rukhsana, Kousteni, Margarita, Kovac, Maja, Kozak Eskenazia, Alex, Krasauskas, Kestutis, Krishnamurthy, Raghu, Krishnamurthy, Vinodh, Krishnan, Manju, Krishnan, Hari, Krizak, Suzanne, Krupej, Sean, Kubisz-Pudelko, Agnieszka, Kudsk-Iversen, Soren, Kudzinskas, Aurimas, Kukadiya, Chirag, Kulkarni, Nainesha, Kumar, Aditi, Kumar, Mayur, Kumar, Ramesh, Kumar, Ravi, Kumar, Rita, Kumar, Rupa, Kumar, Satish, Kumar, Vimal, Kundu, Arun, Kunst, Heinke, Kurani, Amit, Kurdy, Mohammed, Kurian, Rincy, Kurmars, Vimal, Kuronen-Stewart, Cameron, Kusangaya, Ranganai S, Kushakovsky, Vlad, Kuverji, Apexa, Kyei-Mensah, Amma, Kyere-Diabour, Thyra, Kyi, Moe, Kyi, Nyan May, Kyle, Laura, Kyriaki, Karali-Tsilimpari, Labao, Julius, Lacey, Louise, Lack, Nikki, Ladlow, Emma, Lafferty, Heather, Laha, Shondipon, Lahane, Sushil, Lai, Clement, Lai, James, Laing, Robert, Laing-Faiers, Inez, Laity, Emily, Lakeman, Nicki, Lalloo, David, Lalloo, Fiona, Lam, Alison, Lamb, Fiona, Lamb, Lucy, Lamb, Thomas, Lambert, Pauline, Lameirinhas, Claudia, Lami, Mohammed K G, Lamikanra, Abigail, Lamont, Holly, Lamparski, Michal, Lamrani, Djillali, Lanaghan, Christine, Lancona-Malcolm, Ivone, Landers, Geraldine, Landray, Martin J, Lane, Matthew, Lane, Nicholas, Lang, Alidih, Lang, Stephen, Langer, Daniel, Langley, Margaret, Langoya, Charles, Langthorne, Emily, Large, Taiya, Lason, Wojciech, Last, Anna, Latham, Scott, Latham, Victoria, Latham-Mollart, John, Latheef, Afzal, Latt, Nang, Lau, Dawn, Lau, Eva, Laurenson, Myra, Law, Hou, Law, Jessica, Law, Penny, Law, Richard, Lawrence, Emma, Lawrence, Neil, Lawrie, Ryan, Lawson, Louise, Lay, Michael, Laycock, Christine, Layug, Reina, Lazo, Maria, Le, Vietland, Lea, Amelia, Lea, William, Leadbitter, Ian, Leahy, Thomas, Lean, Richard, Leandro, Lorna, Leaning, Darren, Leason, Sandra, Ledingham, Marie A, Lee, Emma, Lee, Hannah, Lee, Irish, Lee, Judith, Lee, Sam, Lee, Shi Han, Lee, Simon, Lee, Sindy, Lee, Stephanie, Lee, Tracey, Lee, Xiang, Lee, Robyn, Lees, Diana, Lees, Jennifer, Legge, Helen, Leggett, Julian, Leigh-Ellis, Katie, Leitch, Nicky, Lekoudis, Eleni, Lemessy, Petula, Lemoine, Nicholas, Leng, Katy, Lennon, Katrina, Lennon, Liz, Leonard, Kelly, Leong, Wen, Leopold, Nicky, Lepiarczyk, Oskar, Leslie, Isla, Lester, Eleni, Leuschner, Ullrich, Levell, Emma, Levett, Chris, Lewin, Alice, Lewis, Alison, Lewis, David, Lewis, Dee, Lewis, Joanne, Lewis, Joseph, Lewis, Kathryn, Lewis, Keir, Lewis, Leon, Lewis, Marissa, Lewis, Rob, Lewis, Robert, Lewis-Clarke, Catherine, Lewszuk, Adam, Lewthwaite, Penny, Ley, Samantha, Liao, Angela, Licence, Victoria, Lieberman, David, Liebeschuetz, Susan, Lightfoot, Nicky, Lillie, Patrick, Lim, Ben, Lim, Carys, Lim, Ee Thong, Lim, Ivy, Lim, Terence, Lim, Wei Shen, Lim, Wilson, Limb, James, Limbu, Usha, Linares, Christian, Linden, Dermot, Lindergard, Gabriella, Lindley, Kate, Lindsay, Charlotte, Lindsay, Emily, Lindsay, Max, Lindsay- Clarke, Helen, Ling, Mirella, Lingam, Claire, Linkson, Linette, Linney, Mike, Linsell, Louise, Lippold, Conrad, Lipscomb, George, Lipscomb, Karen, Lipskis, Laura, Lisboa, Ana, Lister, Evangeline, Little, Jeff, Little, Sam, Liu, Xuedi, Llanera, Daniel K, Llewellyn, Rhiannon, Llewelyn, Martin, Lloyd, Aaron, Lloyd, Adam, Lloyd, Aimee, Lloyd, Arwel, Lloyd, Oliver, Lloyd, Richard, Lo, Su, Loader, David, Lock, Lydianne, Lock, Sara, Lock, Stephen, Locke, Angela, Locke, Jacqueline, Locke, Thomas, Lockett, Teresa, Lodge, Jeorghino, Lofthouse, Martina, Loftus, Heather, Logan, Meg, Logue, Chloe A, Loh, Sook Yin, Lokanathan, Siddharth, Lomme, Kaatje, London, Emily, Long, Gabriella, Long, Natalie, Longhurst, Bev, Longshaw, Mark, Lonnen, Jennifer, Lonsdale, Caroline, Looby, Laura, Loosley, Ronda, Lopez, Paola, Lopez, Paula, Lord, Robert, Lorimer, Claire, Loro, Francesco, Lorusso, Rachel, Loveless, Robert, Lovell, Maxine, Loverdou, Angeliki, Low, Andrew, Low, Jen Mae, Lowe, Alastair, Lowe, Catherine, Lowe, Emily, Lowe, Faye, Lowe, Michael, Lowsby, Richard, Lowthorpe, Vicki, Lubimbi, Gamu, Lubina Solomon, Alexandra, Lucas, Georgia, Lucas, Jacob, Lucey, Alice, Lucey, Olivia, Luck, Suzanne, Luintel, Akish, Luke, H, Luke, Jane, Lungu, Naomi, Lunia, Apurva, Lunn, Muriel, Luo, Ji, Luximon, Cindy N, Lyell, Barrie, Lyka, Elisavet, Lynas, Audrey, Lynch, Ceri, Lynch, Daniel, Lynch, Daniella, Lynch, Stephen, Maamari, Rea-Grace, Mabb, Hannah, Mabelin, Louies, Macaro, Jessica, Macconaill, Kateryna, Macdonald, Chloe, Macfadyen, Claire, Macfarlane, James G, Macfarlane, Jill, Macfarlane, Laura, MacInnes, Lisa, MacIntyre, Iain, MacIntyre, Jill, Mack, Kirsten, Mackay, Callum, Mackay, Euan, Mackay, Laura, Mackenzie, Alexander, Mackenzie, Matt, MacKenzie Ross, Robert, Mackey, Ami, Mackie, Fiona, Mackie, Robert, Mackinlay, Carolyn, Mackintosh, Claire, Mackintosh, Katherine, MacLeod, Mary J, Macmahon, Michael, MacNair, Andrew, Macphee, Catherine, Macpherson, Iain, Macrae, Catriona, MacRaild, Allan, Madden, Alannah, Madden, Mary, Madeja, Norman, Madhivathanan, Pradeep, Madhusudhana, Madhavi, Madu, Alpha, Madziva, Lorraine, Mafham, Marion, Magee, Nick, Magezi, Frederick, Maghsoodi, Negar, Magier, Christopher, Magriplis, Marios, Mahabir, Natasha, Mahadevan-Bava, Subramanian, Maharajh, Anjanie, Maharjan, Kijan, Mahaveer, Ajit, Mahay, Bal, Mahay, Kanta, Mahdi, Hibo, Mahendiran, Thushika, Mahendran, Siva, Maher, Sarah, Maheswaran, Anistta, Maheswaran, Shameera, Maheswaran, Tina, Mahjoob-Afag, Parisa, Mahmood, Ahmed, Mahmood, Farhana, Mahmood, Waheed, Mahmood, Zahra, Mahmoud, Hager, Mahony, Ewan, Mair, Luke, Majekdunmi, Toluwani, Majid, Kesson, Major, Rupert, Majumdar, J, Majumdar, Jaydip, Majumder, Mohammad K H, Makin, Stephen, Malanca, Marius, Malcolm, Hannah, Malein, Flora, Malhan, Neeraj, Malik, Ayesha, Malik, Gulshan, Maljk, Mohammed, Mallett, Paul, Mallinder, Petrina, Mallison, Georgia, Mallon, Louise, Malone, Edward, Maloney, Gracie, Mamman, Madhu, Man, Irene, Man, Kathy, Mancinelli, Rossana, Mancuso-Marcello, Marco, Manders, Tracy, Manderson, Lauren, Mandeville, Justin, Manhas, Roope, Maniero, Carmen, Manikonda, Ravi, Mann, Bobby, Manning, Jonathan, Mannion, Pascoe, Mansi, Katherine, Manso, Katarina, Mansour, Dina, Mapfunde, Isheunesu T, Mappa, Predeesh, Maraj, Hemant, Marchand, Clare, Marcus, Neil, Marecka, Maria, Margabanthu, Gomathi, Margalef, Jordi, Margarit, Lavinia, Margaritopoulos, Georgios, Margarson, Mike, Maria del Rocio, Fernandez M, Maria Pfyl, Teresa, Mariano, Victor, Maric, Ashleigh, Markham, Grace, Marks, Maria, Marks, P, Marouzet, Elisabeth, Marriott, Arran, Marriott, Cheryl, Marriott, Nemonie, Marsden, Brian, Marsden, Christopher, Marsden, Karen, Marsden, Paul, Marsden, Sarah, Marsden, Tracy, Marsh, Robyn, Marshall, Adam, Marshall, Andrew, Marshall, Gail, Marshall, Henry, Marshall, Jaimie, Marshall, Jenna, Marshall, Nicola, Marshall, Riley, Marshall, Jennifer, Martin, Emmeline, Martin, Hayley, Martin, Hope, Martin, Jane, Martin, Karen, Martin, Kate, Martin, Laila, Martin, Michael, Martin, Noelia, Martin, Tim, Martin, Winston, Martin, Sarah, Martindale, Tim, Martineau, Marcus, Martinez, Lauren, Martinez Garrido, Jose C, Martin-Lazaro, Juan, Martins Ferreira, Lucas, Maruthamuthu, Vijay K, Maryan, Gemma, Mary-Genetu, Roman, Maryosh, Sam, Masani, Vidan, Maseda, Diego, Mashate, Sheila, Mashhoudi, Yasaman, Mashta, Al, Masih, Izhaq, Masih, Sanna, Maskell, Nick, Maskell, Perry, Masoli, Matthew, Mason, Rebecca, Mason, Richard, Mason, Ruth, Mason, Claire, Masood, Mohammad, Masood, Mohammad T, Masood, Syed S M E, Masud, Aaqib, Matapure, Lear, Matei, Cristina, Matewe, Ropafadzo, Matharu, Manraj, Mathen, Stephy, Mather, Alex, Mather, Nicole, Mathers, Jonathan, Matheson, Joanna, Mathew, Amal, Mathew, Anna, Mathew, Moncy, Mathew, Verghese, Mathews, Jesha, Mathias, Kate, Mathioudakis, Alexander, Matila, Darwin, Matimba-Mupaya, Wadzanai, Matin, Nashaba, Matisa, Elina, Matonhodze, Max, Matovu, Elijah, Mattappillil, Jaysankar, Matthews, Alison J, Matthews, Heather, Matthews, Helen, Maxton, Fiona, Maxwell, Adam, Maxwell, Veronica, May, James, May, Joanne, May, Philippa, Mayanagao, Irving, Maycock, Matthew, Mayers, Graham, Maynard, Victoria, Mayor, Shelley, Mazen, Ibreaheim, Mazzella, Andrea, Mburu, Nyambura, McAleese, Eleanor, McAlinden, Paul, McAlpine, Audrey, McAlpine, Graeme, McAndrew, Jonathan, McAuley, Hamish, McAuliffe, Sarah, McBrearty, Claire, McBride, Erin, McBuigan, Michael, McBurney, James, McCabe, Laura, McCairn, Amanda, McCammon, Jake, McCammon, Nicole, McCann, Conor, McCann, Erin, McCarrick, Alexandra, McCarron, Brendan, McCarthy, Eoghan, McCarthy, Michelle, McCarthy, Natalie, McCaughey, Sinead, McChlery, Gareth, McClay, Tara, McClelland, Beverley, McClintock, Declan, McCormack, Patricia, McCormick, Jacqueline, McCormick, Wendy, McCourt, Paul, McCrae, Jame, McCready, Sharon, McCreath, Gordan, McCreedy, Helen, McCullagh, Iain J, McCullagh, Liz, McCullagh, Megan, McCullough, Conor, McCullough, Katherine, McCullough, Nicola, McCullough, Sarah, McCurrach, Fiona, McDermott, Paula, McDermott, Rory, McDevitt, Katharine, McDill, Helen, McDonald, Basil, McDonald, Claire, McDonald, Debbie, McDonald, Rob, McDonald, Sam, McDonald, Damhnaic, McDougall, Rowan, McEleavy, Irene, McEntee, Julie, McEvoy, Evanna, McEwen, Ruth, McFadden, Margaret, McFarland, Denise, McFarland, Margaret, McFarland, Rachel, McGarry, Erin, McGarvey, Lorcan, McGenily, Laura, McGettigan, Clodagh, McGettrick, Michael, McGhee, Christopher, McGill, Fiona, McGinnity, Sarah, McGivern, Hannah, McGlinchey, Neil, McGlone, Phil, McGlynn, Deborah, McGoldrick, Claire, McGoldrick, Clare, McGough, Elizabeth, McGrath, Brendan, McGregor, Amanda, McGregor, Annemarie, McGuinness, Heather, McGuire, Sean, McHugh, Tara, McInnes, Caroline, McInnes, Neil, McIntyre, Karen, McIntyre, Mhairi, McKay, Lorna, McKeag, Conor P, McKee, Madeleine, McKeever, Joseph, McKenna, Shirley, McKeogh, Donogh, McKerr, Caroline, McKie, Anthony M, Mckie, Laura, McKnight, Gerard, McLachlan, Heather, McLaren, Andrew, McLaren, Barbara, McLarty, Nicola, McLaughlin, Maria, McLay, James, McLeish, Mary, McLennan, Tina, McLure, Stewart, McMahon, Anne-Marie, McMahon, Genevieve, McMahon, Mike, McMahon, Stephen, McManus, Terence, McMaster, Moyra, McMaster, Paddy, McMeekin, Samuel, McMillan, Nicola, McMinn, Jason, McMorrow, Liam, McNally, Helen, McNeela, Fiona, McNeil, Lynne, McNeill, Claire, McNeill, Shea, McNelis, Una, McNulty, Melanie, McNulty, Roisin, McParland, Christopher, McPhail, Mark, McQueen, Alison, McSkeane, Anna, McSorland, Denise, McTaggart, Gini, McTaggart, Jacqueline, Mead, Joanna, Meadows, Emma, Meakin, Olivia, Mearns, Ben, Mearns, Claire, Mears, Kim, Mears, William, Meda, Manjula, Mediana, Ayren, Medine, Ross, Medveczky, Thomas, Meehan, Sharon, Meeks, Emily, Megan, Abbi, Meghani, Nevan, Meghjee, Salim, Mehar, Amina, Mehra, Rohan, Meiring, James, Mejri, Rayane, Melander, Sabina, Melinte, Adriana-Stefania, Mellor, Francesca, Mellor, Samantha, Mellor, Zoe, Mellows, Katrina, Melnic, Vladimir, Melville, Alice, Melville, Julie, Membrey, Helen, Mencias, Mark, Mendonca, Cheryl, Mentzer, Alexander, Menzies, Dan, Mepham, Sue, Mercer, Oliver, Mercer, Pauline, Merchant, Arwa, Merchant, Fatema, Mercioniu, Mihaela, Meredith, Megan, Merida Morillas, Marta, Merrick, Blair, Merritt, Jack, Merritt, Simon, Merwaha, Ekta, Message, Simon, Metcalf-Cuenca, Gabriel, Metcalfe, Benjamin, Metcalfe, Kneale, Metherell, Stella, Metryka, Alexsandra, Mew, Louise, Meyrick, Simon, Mguni, Nhlanhla, Miah, Atiqa, Miah, Jagrul, Miah, Nahima, Mic, Gabriela, Micallef, Dariush, Michael, Alice, Michael, Angiy, Michael, Shery, Michalak, Natalia, Michalca-Mason, Loredana, Middle, Janet, Middleton, Hayley, Middleton, Jennifer T, Middleton, Maeve, Middleton, Sophie, Mieres, Shelley, Mihalca-Mason, Loredana, Mikolasch, Theresia, Milgate, Sarah, Millar, Colin, Millar, Jonathan, Millard, James, Miller, David, Miller, Johnathan, Miller, Lucy, Miller, Rachel, Miller-Biot, Naomi, Miller-Fik, Alex, Millett, Louise, Milligan, Hazel, Milligan, Iain, Milliken, Caitlin, Millington, Katherine, Millington, Samuel, Mills, Helen, Mills, Janet, Millward, Helen, Millward, Sebastian, Miln, Rebecca, Milne, Alice, Milne, Charlotte, Milne, Louise, Milner, Joanne, Min, Zayar, Mindel, Samuel, Minnis, Chrissie, Minnis, Paul, Minton, Jane, Miranda, Frederico, Mirza, Taimur, Misbahuddin, Anjum, Mishra, Aseem, Mishra, Biswa, Mishra, Eleanor, Mishra, Ritu, Misra, Sannidhya, Mistry, Deena, Mistry, Heena, Mital, Dushyant, Mitchard, Sarah, Mitchell, Ben, Mitchell, Piers, Mitchelmore, Philip, Mitra, Andrew, Mitra, Atideb, Mitra, Sandip, Moakes, Emma, Moatt, Emma, Modgil, Gita, Mohamed, Abdelrahman, Mohamed, Arez, Mohamed, Osab, Mohammad, Waheed, Mohammed, Aliabdulla, Mohammed, Omer, Mohammed, Yaser N S, Mohamud, Bilal A, Moharram, Amr, Mok, Hoi-Ping, Mok, Jonathan, Moller-Christensen, Christine, Mollet, Mateus, Molloholli, Malid, Molloy, Aoife, Molloy, Linda, Molyneux, Andrew, Momoniat, Tasnim, Monaghan, Holly, Monaghan, Krista, Mongolu, Shiva, Monika, Tesha, Monsell, Katelyn, Montasser, Mahmoud, Montgomery, Alan, Montgomery, Hugh, Moodley, Prebashan, Moody, Margaret, Moody, Nick, Moon, Angela, Moon, James, Moon, Ji-Hye, Moon, Maria, Moonan, May, Moondi, Parvez, Moore, Alex, Moore, Christopher, Moore, David A J, Moore, Faye, Moore, Judith, Moore, Laura, Moore, Sally, Moore, Sonia, Moores, Rachel, Morab, Ed, Morales, Jose, Moramorell, Nuria, Moran, Louise, Moray, Grishma, Moreno-Cuesta, Jeronimo, Morgan, Amy, Morgan, Caitlin, Morgan, Christine, Morgan, Colin, Morgan, Lauren, Morgan, Leila, Morgan, Matthew, Morgan, Patrick, Morgan-Jones, Katie, Morgan-Smith, Emily, Morley, Anna, Morley, Thomas, Morley, Wendy, Morris, Anna, Morris, Damian, Morris, Fiona, Morris, Helen, Morris, Juliet, Morris, Katie, Morris, Laura, Morris, Lucy, Morris, Mary-Anne, Morris, Niall, Morris, Paul, Morris, Sheila, Morris, Susan, Morrison, Douglas, Morrison, Moira, Morrison, Scott, Morrissey, Mary, Morrow, Anna, Morselli, Franca, Mortem, Gordon, Mortland, Valerie, Morton, Chelsea, Morton, Gordon, Morzaria, Priti, Moss, Alison, Moss, Charlotte, Moss, Sarah, Moss, Stuart, Motherwell, Nicki, Mouland, Johanna, Moulds, Caroline, Moulton, Hilary, Mousley, Elizabeth, Moxham, Karen, Moya, Borja, Moyo, Quberkani, Mshengu, Eunice, Mtuwa, Sheila, Muazzam, Ali, Muazzam, Iqtedar A, Muchenje, Nykki, Mudawi, Dalia, Muddegowda, Girish, Mugal, Imran, Mughal, Ahsan, Muglu, Javaid, Muhammad, Javed, Muir, Carol, Mukherjee, Dipak, Mukhtar, Syed A A, Mukimbiri, Denise, Mulgrew, Peter, Mulhearn, Ben, Mulla, Arafat, Mullan, Dee, Mullasseril Kutten, Dileepkumar, Mullen, Niall, Mullett, Rosemary, Mulligan, Sandra, Mumelj, Lana, Mumford, Andrew, Munavvar, Mohammed, Munby, Henry, Munro, Anne-Marie, Munt, Sheila, Mupudzi, McDonald, Murad, Arshid, Muraina, Oluwatosin H, Muralidhara, Koteshwara, Murdoch, Mhairi, Murira, Jennifer, Murphy, Alison, Murphy, Carl, Murphy, Gail, Murphy, Peter, Murphy, Sheenagh, Murphy, Simon, Murray, Clare, Murray, David, Murray, Eleanor, Murray, Katie, Murray, Kenneth, Murray, Lisa, Murray, Lorna, Murray, Tracey, Murtagh, Eoin, Murthy, Mithun, Murton, Catherine, Murton, Rosie, Muru, Neeka, Musanhu, Rosemary, Mushabe, Maimuna, Mushtaq, Omaisa, Mustafa, Ahmed M M, Mustafa, Elhaytham, Mustafa, Mustafa, Mustapha, Ibrahim, Mustufvi, Zhain, Mutch, Callum, Mutema, Eric, Muthukrishnan, Balakumar, Mutton, Sheree, Muzengi, Natasha, Mwadeyi, Memory, Mwale, Bettina, Mwaura, Esther, Myagerimath, Raji, Myers, Alice, Myers, Sam, Myint, Khin Swe, Myint, Yadee, Myslivecek, Libor, Nadar, Evelyn, Nadeem, Iftikhar, Nadheem, Moosa, Naeem, Asma, Naeem, Hassan, Naeem, Salman, Nafees, Samraiz, Nafei, Mohamed, Nagarajan, Thapas, Nagra, Imrun, Nagra, Deepak, Naguib, Mina, Naguleswaran, Kirushthiga, Nagumantry, K Shonit, Naicker, Kevin, Naidoo, Sarveshni, Naik, Gireesha, Naik, Rishi, Naik, Samir, Nair, Devu S, Nair, Rajiv, Nair, Tanushree, Naisbitt, Jay, Naismith, Kerry, Nallapareddy, Sri, Nallapeta, Soum, Nallasivan, Arumugan, Nanda, Uttam, Nandani, Aarti, Naqvi, Ali Raza, Naqvi, Asadullah, Naqvi, Sara, Nasa, Sophia, Nash, Dominic, Nasheed, Nader, Nasimudeen, Abdul, Nasir, Umer, Nasser, Tahir, Natarajan, Anuja, Natarajan, Geetha, Natarajan, Nalin, Natarajan, Nikhila, Natarajan, Rajkumar, Nathaniel, Noel, Nathvani, Mala, Nathwani, Priyan, Nava, George, Navaneetham, Neena, Navaratnam, Jeya, Navarra, Helen, Naveed, Sadaf, Navin, John, Nawaz, Khuteja, Nawaz, Sarfaraz, Nawaz, Shasta, Nayar, Bonilla, Naylor, Suzanne, Nayyar, Moez, Naz, Farrah, Naz, Mobeena, Nazari, Babak, Nazir, S, Nazir, Sehar, Ncomanzi, Dumisani, Ndefo, Onyine, Neal, Alan, Neary, Elaine, Negmeldin, Mostafa, Neill, Paula, Neils, Hector E, Nejad, Avideah, Nel, Louise, Nelson, Marie, Nelson, Richard, Nelson, Scott, Nelwan, Erni, Nemane, Rajesh, Nepal, Samiksha, Nethercott, Daniel, Netherton, Kimberley, Nettleton, Kimberley, Newby, Alison, Newby, Angela, Newby, David, Newcombe, Tracy, Newman, Diana, Newman, Julie, Newman, Oscar, Newman, Tabitha, Newman, Thomas, Newport, Rachel, Newton, Maria, Ng, Anthony Y K C, Ng, Ka Wing, Ng, Maxine, Ng, Sarah, Ng, Wee Jin, Ngan, Thomas, Ngui, Gabriel CE, Ngumo, Alice, Nic Fhogartaigh, Caoimhe, Nicholas, Nathalie, Nicholas, Philip, Nicholls, Donna, Nicholls, Lisa, Nicholson, Alice, Nicholson, Anne, Nicholson, Annette, Nickson, Ian, Nicol, Eileen, Nicol, Elizabeth, Nicol, Rebecca, Nicola, Pantelis, Nicoll, Antony, Nikolaos, Pantzaris, Nikonovich, Georgii, Nilsson, Annette, Nimako, Kofi, Nimako, Louise, Nimmo, Camus, Ninan, Preethy, Nirmalan, Mahesh, Nisar, Muhammad, Nisbett, Toby, Nisha James, Aksinya, Nishat, Sabaahat, Nishiyama, Tomoko, Nix, Sara, Nixon, Jennifer, Nixon, Maxine, Nizam Ud Din, Khwaja, Nizami, Maria, Noba, Lyrics, Noble, Harriet, Noe, Hsu M, Nolan, Jerry, Noor, Zahid, Noori, Zaid, Norman, Louis, Norman, Rachel, Norris, Karen, Norris, Lillian, Nortcliffe, Sally Ann, North, Fiona, North, Julie, North, Thomas, Northfield, John, Northover, Samantha, Nortje, Jurgens, Norton, Donna, Norton, Rowen, Notman, Holly, Nourein, Khalid, Novak, Timea, Nugdallah, Mohamed, Nugent, Anne Marie, Nugent, Justine, Nundlall, Kribashnie, Nune, Arvind, Nunn, Kieran, Nunn, Michelle, Nunnick, Jane, Nupa, Yvonne, Nurgat, Zubeir, Nyamugunduru, Godfrey, Nyirenda, Maggie, Nyland, Kerry, O Shea, Daire, O'Hara, Chloe, O'Reilly, Kevin, O'Rourke, William, Oakley, Caroline, Obale, Begho, Oboh, Clements, O'Brien, Clare, O'Brien, Julie, O'Brien, Kirsty, O'Brien, Linda, O'Brien, Neale, O'Brien, Rachel, O'Brien, Tracey, O'Bryan, Emma, Obukofe, Ross, O'Callaghan, Christopher, O'Connell, Lorcan, OConnor, Tadg, O'Connor, Chris, O'Connor, Grainne, Odam, Miranda, Oddie, Sam, Oddy, Sharon, Odedina, Yejide, Odedra, Krishma, Odelberg, Sven W, Odell, Natasha, Oderinde, Omolola, Odone, Jessica, O'Donovan, Catherine, O'Farrell, Stephen, Offord, Pamela, Ogbara, Tanwa, Ogilvie, Catherine, O'Gorman, Ciaran, Ogunkeye, Oluwatomilola, Ohia, Udeme, Ohja, Shinjali, Ojo, Ohiowele, O'Kane, Mark, Okeke, Tolu, OKell, Eleanor, Okines, Alicia, Okpala, Iheoma, Okpo, Ernest, Okpoko, F, Okubanjo, Maryanne, Olaiya, Raphael, Old, Tim, Oleszkiewicz, Gregory, Oliveira, Marta, Oliver, Annie, Oliver, Catherine, Oliver, Jesse, Oliver, Martyn, Oliver, Zoe, Olokoto, Nurudeen O, Olonipile, Folusho, Olufuwa, Olumide, Olukoya, Olatomiwa, Oluwole-Ojo, Akinlolu, O'Malley, Laura, Omar, Maryam, Omar, Zohra, Omer, Nimca, O'Neill, Connaire, O'Neill, Lauran, Ong, Chon Sum, Onyeagor, Chidera, Ooi, Huah Chiang, Oomatia, Amin, Opena, Maria, Oram, Richard, Ord, Christy, Ord, Jonathan, Orekoya, Lola, O'Riordan, Devaki, O'Riordan, Sean, Orme, Amy, Orme, Hannah, Orr, Charlotte, Orr, Sarah, Orton, Christopher, Osadcow, Anna, Osagie, Rawlings, Osanlou, Rostam, Osborne, Lynn, Osborne, Nigel, Osborne, Rebecca, Osborne, Wendy, Osborne, William, Osbourne, Charles, Osei-Bobie, Jennifer, Osman, Joseph, Osman, Wa'el, Osman, Bashir, Osoata, G, Ostermann, Marlies, O'Sullivan, Eoin, O'Sullivan, Susan, Otey, Noor, Otite, Otheroro K, O'Toole, Marie, Otter, Ashley David, Owen, Rachel, Owen, Stephanie, Owens, Emma, Owoseni, Yetunde, Owston, Michael, Oxlade, Ruth, Ozdes, Feray, Pack, Jamie, Packham, Sophie, Paczko, Piotr, Padden, Grace, Padmakumar, Anand, Page, Iain, Page, Joseph, Page, Valerie, Paget, Jodi, Pagett, Katherine, Paisley, Lee, Pajak, Susie, Pakozdi, Angela, Pal, Soubhik, Pal, Sushi, Palacios, April, Palagiri Sai, Vishnu B, Palaniappan, Vadivu, Palanivelu, Priya, Palfreeman, Adrian, Palit, Deepshikha, Palmer, Alistair, Palmer, Lynne, Pamphlett, Ian, Pan, Daniel, Pandey, Anmol, Pandian, Nithya, Pandya, Krishnaa, Pandya, Tej, Panes, Alice, Pang, Yee Wei, Pannell, Laura, Pannu, Kanwar, Pant, Suman, Panthakalam, Sathianathan, Pantin, Charles T, Pao, Norman, Papaconstantinou, Helen, Papineni, Padmasayee, Paques, Kitty, Paradowski, Kerry, Parambil, Vinay, Paranamana, Supathum, Parashar, Siddhant R, Parberry, Ian, Parekh, Amy, Parekh, Dhruv, Parfitt, Louise, Parfrey, Helen, Parikh, Omi, Parish, Gemma, Park, John, Parker, Angela, Parker, Ben, Parker, Emma, Parker, Jacob, Parker, Julie, Parker, Laura, Parker, Lucy, Parker, Sara, Parker, Sean, Parkin, Kirstin, Parkinson, Anna, Parkinson, Valerie, Parmar, Chetan, Parmar, Viraj, Parris, Victoria, Parry, Helen C, Parslow-Williams, Siobhan, Parsonage, Maria, Parsons, Penny, Partridge, Richard, Parvin, Kevin, Passby, Lauren, Passey, Samuel, Pastrana, Juan, Patal, Mital, Patch, Sarah, Patel, Aamie, Patel, Alkesh, Patel, Amisha, Patel, Dakshesh, Patel, Darshna, Patel, Hemani, Patel, Jaymik, Patel, Kamal, Patel, Kayur, Patel, Kiran, Patel, Krish, Patel, Manish, Patel, Martyn, Patel, Mehul, Patel, Naleem, Patel, Nehalbhai, Patel, Prital, Patel, Saagar, Patel, Soonie, Patel, Trishna, Patel, Vishal, Pathak, Sangeeta, Pathan, Nazima, Patience, Alexandra, Patience, Donna, Patrick, Abigail, Patrick, Georgie, Patrick, Jean, Patten, Simon, Pattenden, Ben, Patterson, Charlotte, Patterson, Linda, Patterson, Molly, Patterson, Robert, Paul, Suman, Pauls, Leigh, Paulus, Stephane, Pavely, Amelia, Pavord, Susan, Payne, Brendan, Payne, Elizabeth, Payne, Ruth, Peacock, Linda, Peacock, Louise, Peacock, Sarah, Peake, Henry, Pearce, Jasmine, Pearse, Rupert, Pearson, Andrew, Pearson, Daniel, Pearson, Harriet, Pearson, Karen, Pearson, Samuel A, Pearson, Sandra, Peasley, Alice, Peddie, Hilary, Peek, Russell, Pegg, Claire, Peglar, Suzannah, Peirce, Benjamin H, Pelham, Claire, Pemberton, Abigail, Penacerrada, Melchizedek, Pender, Anthony, Pendlebury, Carmel, Pendlebury, Jessica, Penfold, Rachel, Penman, Catherine, Penman, Julie, Penman, Rachel, Penner, Justin, Penney, Kristi, Penny, James, Pepperell, Justin, Pereira, Adriana, Pereira, Rita, Pereira Dias Alves, Carlota, Perez, Elena, Perez, Jane, Perinpanathan, Tanaraj, Periyasamy, Lakshmi, Perritt, Elizabeth, Perry, Alison, Perry, Emily, Perry, Meghan, Perumpral, Thomas M, Pessoa-Amorim, Guilherme, Petch, Ruth, Peter, Lionel, Peters, Cecilia, Peters, Mark, Peters, Steve, Peters, Tim, Petersen, Remy, Peterson, Alexandra, Peto, Leon, Petras, Iulia, Petrova, Boyanka, Petrova, Mirela, Pfeffer, Paul, Phanish, Mysore, Phelan, Paul, Philbey, Christopher, Philbin, Jennifer, Phillips, Alex, Phillips, Dylan, Phillips, Rachael, Phipps, Marie, Phongsathorn, Virach, Phull, Mandeep, Pick, Sara, Pickard, James, Pickering, Charlotte, Pickering, Gillian, Pickett, Thomas, Pickford, Hayleah, Pickles, Joanna, Pickwell-Smith, Benjamin, Pieniazek, Natalia, Piercy, Charlie, Pieris, Angelo, Pilgrim, Samia, Pillai, Paul A, Pilsworth, Zoe, Pinches, Heather, Pinches, Stacey, Pine, Kirsty, Pinjala, Muni T, Pintus, Stefania, Piper, Graeme, Pirani, Tasneem, Pittman, Marcus, Pitts, Sally, Plaatjies, Nicolene, Platt, Naomi, Pleass, Robert, Ploeg, Rutger, Plummer, Laura, Plumptre, Charles, Pobjoy, Jonathan, Pogreban, Tatiana, Poku, Stephen, Pollard, Rachel, Pollock, Louisa, Poluyi, Oluwamayowa, Polwarth, Gary John, Pomery, Fiona, Ponnusamy, Ponmurugan, Ponnusamy, Suresh, Ponnuswamy, Aravind, Ponte Bettencourt dos Reis, Inês, Pooboni, Suman, Poole, Alice, Poole, Lynda, Poole, Michele, Poon, Sharon, Poonian, Tajinder, Porter, David, Porter, Jo, Porter, Linda, Porter, Ross, Postlethwaite, Kelly, Pothina, Narayana, Potla, Priyadarshan, Potoczna, Dorota, Pott, Jason, Potter, Alison, Potter, Jean, Potter, Sarah, Potter, Tracey, Potton, Elspeth, Potts, Joanne B, Potts, Julie, Potts, Kathryn, Poudyal, Beli, Poultney, Una, Poulton, Katherine, Poustie, Vanessa, Powell, James, Powell, Jordan, Power, Deborah, Power, Nick, Powter, Gillian, Poxon, Joseph, Poyner, Robin, Pradhan, Vidushi, Prady, Helena, Prasad, Aalekh, Prasad, Krishna, Prasanth Raj, Fredy, Prasath, Sangeetha, Pratheepkumar, Sindhuja, Pratley, Anezka, Pratt, Steven, Preiss, David, Prendergast, Claire, Prentice, Lynn, Prentice, Peter, Prescott, Verity, Presland, Laura, Prest, Catharine, Preston, Stephen, Pretorius, Martha, Prevatt, Natalie, Prew, Sandra, Price, Ashley, Price, Carly, Price, Claire, Price, David, Price, Elizabeth, Price, Nathan, Price, Vivien, Priest, Anne, Prieto, Jimena, Primrose, Lorraine, Prince, Clare, Prince, Judith, Prince, Laura, Pringle, Shirley, Pristopan, Veronika, Pritchard, Kelly, Pritchard, Lucy, Pritchard, Simon, Priyash, Verma, Procter, Andrew, Proctor, Clare, Proudfoot, Rebecca, Prudon, Ben, Pryor, David, Pudi, Solomon, Pugh, Joanne, Pugh, Lawrence, Pugh, Mark T, Pugh, Nichola, Pugh, Richard, Puisa, Veronika, Punia, Kirandip, Punnilath Abdulsamad, Saleel, Purandare, Laura, Purchase, Daniel, Purdue, Corrina, Purewal, Bally, Pursell, Molly, Purssord, Gregory, Purves, Rory, Purvis, Sarah, Puspatriani, Khairunnisa, Puxty, Kathryn, Puyrigaud, Zoe, Pynn, Michael, Qadeer, Tariq, Qayum, Mohammad, Quah, Corrine, Quaid, Sheena, Quail, Nathaniel, Quamina, Charlotte, Quayle, Alice, Quek, Eleanor, Quenby, Siobhan, Qui, Xinyi, Quick, Vanessa, Quigley, Julie, Quijano-Campos, Juan-Carlos, Quinn, Andrew, Quinn, James, Quinn, Tom, Quratulain, Quratulain, Qureshi, Danya, Qureshi, Ehsaan, Qureshi, Hasanain, Qureshi, Khadija, Qureshi, Nawaz, Qurratulain, Qurratulain, Qutab, Saad, Rabbani, Muhammad S, Rabinowicz, Simon, Raceala, Madalina, Rachman, Raissa, Rad, Laura, Radford, Jane, Radford, Liz, Radhakrishnan, Jayachandran, Rafique, Cecillia, Rafique, Jethin, Rafique, Muhammad, Ragatha, Ravi, Raghunathan, Aiswarya, Raguro, Abigail, Raha, Shankho D, Rahama, Sana, Rahardjani, Mutia, Rahilly, Karen, Rahim, Faisal, Rahimi, Abdul H, Rahimi, Haseena R, Rahman, Muhammad, Rahman, Salim Ur, Rai, Prajan, Raisova, Lenka, Raj, Arjun, Rajagopalan, Pradeep, Rajaiah, Nithy, Rajalingam, Kanendran, Rajasekaran, Arvind, Rajasri, Aylur, Rajbhandari, Sagar, Rajeswaran, Thurkka, Rajeswary, Jyothi, Rajkanna, Jeyanthy, Rajmohan, Gayathri, Rallan, Ruth, Ralston, Katherine, Ralston, Maximilian, Ram, Matsa, Ramabhadran, Balaji, Ramali, Fathima, Ramali, Mohamed, Ramanan, Athimalaipet, Ramanna, Shashikira, Ramasamy, Maheshi, Rambe, Irfah, Ramdin, Dhanishta, Ramirez, Jozel, Ramirez, Mylah, Ramnarain, Geshwin, Ramos, Lidia, Rampling, Tommy, Ramraj, Shanthi, Ramshaw, Alex, Rana, Aleem, Rana, Ghulam F, Rana, Rehman, Rand, Abby, Rand, James, Randheva, Harpal, Ranga, Poonam, Rangar, Manmeet, Rangarajan, Harini, Ranjan, Sameer, Rank, Hannah, Ranka, Poormina, Rankhelawon, Rajesh, Rao, Anita, Rao, Sandhya, Rao, Sanjay, Rao, Deepak, Rasheed, Althaf A, Rashid, Khalid, Ratcliff, Simbisai, Ratcliffe, Sam, Ratcliffe, Sophy, Rath, Sanjeev, Rather, Mohmad I, Rathore, Selina, Ratnakumar, Aravinden, Ratoff, Jonathan, Rattehalli, Deepa, Raw, Jason, Raw, Rachael, Rawlins, Hywel, Ray, Gautam, Raymond-White, Adam, Raynard, Dana, Rayner, Nicola, Raynsford, Amy, Razvi, Salman, Razvi, Zarine, Read, Kerry, Read, Sarah, Reddy, Ajay, Reddy, Anvesh, Reddy, Harsha, Redfern-Walsh, Aine, Redome, Alex, Redome, Joan, Reed, Anna, Reed, John, Rees, Andrew, Rees, James, Rees, Martyn, Rees, Sarah, Rees, Stephanie, Rees, Tabitha, Regan, Fiona, Regan, Karen, Regan, Susan, Rege, Kanchan, Rehan, Ahmed, Rehman, A, Rehman, Shoib, Rehman, Zainab, Reid, Ada, Reid, Andrew, Reid, Jennifer, Reid, Jeremy, Reid, Sharon, Reilly, Mkyla, Reith, Christina, Remegoso, Alda, Rengan, Dinakaran, Renshaw, Stephen, Renu Vattekkat, Remya, Reschreiter, Henrik, Revels, Mark, Rewitzky, Glynis, Rey, Severine, Reynard, Charles, Reynish, Dominic, Reynolds, Peter, Reynolds, Piero, Rhodes, Jonathan, Riaz, Naghma, Rice, Emily, Rice, Matthew, Rich, Mel, Richards, Alex, Richards, Alison, Richards, Liz, Richards, Suzanne, Richardson, Celia, Richardson, Julie, Richardson, Neil, Richardson, Nicky, Riches, Joanne, Riches, Katie, Richmond, Leah, Richmond, Ruth, Ricketts, William, Rickman, Hannah, Riddell, Anna, Ridha, Mohamed, Ridley, Carrie, Ridley, Paul, Rieck, Gudrun, Rigby, Linsey, Rijal, Samita, Riley, Hannah, Riley, Matthew, Riley, Phil, Rimainar, Atika, Rimba, Zwesty V P, Rimmer, Dominic, Rintoul, Robert, Riordan, Andrew, Ripley, David, Rippon, Naomi, Rishton, Chloe, Riste, Michael, Ritchie, David, Ritchie, Jane, Ritchings, Andy, Rivera Ortega, Pilar, Rivers, Vanessa, Rizvi, Batool, Rizvi, Syed AS, Rizvi, Syed H M, Robb, James, Roberts, David J, Roberts, Ian, Roberts, Jane, Roberts, Jean, Roberts, Karen, Roberts, Mark, Roberts, Nicky, Roberts, Philip, Roberts, Rebecca, Robertson, Calum, Robertson, James, Robertson, Jamie, Robertson, Nichola, Robertson, Stuart, Robin, Nicole, Robinson, Caroline, Robinson, Emma, Robinson, Gisela, Robinson, Hannah, Robinson, Jemima, Robinson, Kate, Robinson, Matthew, Robinson, Ryan, Robinson, Sandra, Robinson, Alexandra, Robson, Steve, Roche, Lisa, Roche, Samantha, Rodden, Natalie, Roddick, Alistair, Roddy, Jack, Roderick, Marion, Rodger, Alison, Rodger, Faye, Rodger, Megan, Rodgers, Alicia, Rodgers, Deirdre, Rodgers, Natasha, Rodgers, Penny, Rodriguez-Belmonte, Rocio, Roe, Nicholas, Roehr, Charles, Rogers, Gill, Rogers, Jason, Rogers, Joanne, Rogers, John, Rogers, Leigh, Rogers, Lindsay, Rogers, Michaela, Rogers, Paula, Rogers, Susan, Rogers, Thomas, Rogers, Paula, Rokadiya, Sakib, Rollins, Lee, Rollo, Jennifer, Rolls, Catherine, Roman, Atal, Rook, Claire, Rooney, Kevin, Rooney, Lynsey, Rosaroso, Lace P, Rose, Alastair, Rose, Annie, Rose, Steve, Rose, Zoe, Rosier, Josephine, Ross, Jack, Rossdale, Jennifer, Rothman, Alex, Rothwell, Joanne, Roughley, Lindsay, Rowan, Kathryn, Rowan, Neil, Rowan, Stephen, Rowe, Anna, Rowe, Cathy, Rowe-Leete, Louise, Rowlands, Benjamin, Rowley, Megan, Roy, Subarna, Royds, Matthew, Roynon-Reed, Anna, Rozewicz, Sam, Rudenko, Anna, Rudrakumar, Senthan, Rudran, Banu, Ruff, Shannon, Rughani, Prita, Rundell, Sharon, Rushmer, Jeremy, Rusk, Darren, Russell, Peter, Russell, Richard, Russo, Cristina, Rutgers, Marieke, Ryan, Aidan, Ryan, Brendan, Ryan, Kathryn, Ryan, Lucy, Ryan, Matthew, Ryan, Pat, Ryan, Phil, Ryan-Wakeling, Declan, Saad, M, Sabale, Javeson, Sabaretnam, Suganya, Sadiq, Noman, Sadler, Emma, Saffy, Ashiq, Sage, Beth, Sagoo, Harkiran, Sagrir, Sobia, Saha, Rajnish, Saha, Sian, Sahdev, Nikhil, Sahedra, Sarvjit, Sahota, Jagdeep, Said, Nooria, Sakthi, Sreekanth, Sakuri, Hikari, Saladi, Murthy, Salam, Abdul, Salberg, Armorel, Salciute, Erika, Saleeb, Gina, Saleh, Mumtaz, Salih, Hizni, Salih, Laylan, Salisbury, Sarah, Saliu, SiteEneye, Salman, Rustam, Salmon, Jenny, Salutous, Dario, Sam, Mfon, Sam, Sally, Samakomva, Tinashe, Saman, Razan, Samar, Sakeena, Samlal, Renaldo, Sammons, Emily, Sammut, David, Sammut, Mark, Sampath, Sunitha, Sampson, Claire, Sampson, Julia, Samson, Aashna, Samson, Anda, Samuel, Johnson, Samuel, Merna, Samuel, Reena, Samuel, Thomas D L, Samuel, Younan, Samuels, Theo, Samways, Joanna, Samyraju, Manjula, Sana, Ilves, Sanchez, Veronica, Sanchez Gonzalez, Amada, Sanda-Gomez, Alina, Sandercock, Peter, Sanderson, Amy, Sanderson, Tom, Sandhi, Prabowo, Sandhu, Kuljinder, Sandhu, Loveleen, Sandow, Sam, Sandrey, Victoria, Sands, Sarah, Sangombe, Mirriam, Sanju, Mathew, Sankaran, Lakshmi, Santos, Filipa, Santosh, Rojy, Sanyal, Jayanta, Sanz-Cepero, Aureo F, Saragih, Dan, Saralaya, Dinesh, Saraswatula, Arun, Sarella, Joshua, Sarfatti, Avishay, Sargent, Rebecca, Sari, Beatrix, Sari, Diah, Sarkar, Khatija, Sarkar, Rahuldeb, Sarma, Sruthi, Sarwar, Zainab, Sass, Thea, Sathe, Sonia, Sathianandan, Sobitha, Sathyanarayanan, Abilash, Sathyanarayanan, Lavanya S J P, Sathyapalan, Thozhukat, Satodia, Prakash, Saulite, Vera, Saunders, Andrew, Saunders, Rachel, Saunders, Samantha, Saunderson, Anne, Savill, Heather, Savlani, Karishma, Saxena, Gauri, Saxton, Matthew, Sayan, Amrinder, Scaletta, Diane, Scanlon, Deborah, Scanlon, Jeremy, Scarratt, Lyndsay, Scattergood, Sean, Schadenberg, Alvin, Schafers, Jenna, Schneblen, Wendy, Schofield, Rebecca, Schofield, Samuel, Scholes, David, Scholes, Karen, Schoolmeesters, Alex, Schumacher, Natasha, Schunke, Nicola, Schuster Bruce, Martin, Schwarz, Karin, Scobie, Antonia, Scorrer, Tim, Scott, A., Scott, Alistair, Scott, Anne, Scott, Catherine, Scott, Christine, Scott, Emily, Scott, Kathyn, Scott, Leanne, Scott, Martha, Scott, Stephen, Scott, Timothy, Scourfield, Sarah, Scrase, Wendy, Scullion, Angela, Scullion, Therese, Seager, Emily, Seagrave, Cathy, Seaman, Rebecca, Sear, Eleanor, Seaton, Isabella, Seckington, Anna, Sedano, Joanna, Seddon, Gabrielle, See, Yee Yong, Seelarbokus, Muhammad A, Sefton, Christopher, Segovia, Matias, Seidu, Fatima, Sekadde, Gillian, Selby, Faye, Selby, Georgina, Sellar, Claire, Sellers, Katharine, Selley, Joseph, Sellick, Victoria, Selman, Hannah, Selvadurai, Gobika, Selvarajah, Brintha, Selvaskandan, Haresh, Selvendran, Subothini S, Selwyn, Jeyakumar, Semple, Gary, Sen, Nandini, Sen, Seema, Sengupta, Aditya, Sengupta, Niladri, Senra, Susana, Senya, HoJan, Setty, Niranjan, Seward, Abigail, Sewdin, Teswaree, Seymour, Jack, Shabbir, Hussam, Shackley, Fiona, Shafi, Tariq, Shah, Aashni, Shah, Ahmar, Shah, Anand, Shah, Bhavni, Shah, Momin, Shah, Neil, Shah, Pallav, Shah, Priyank, Shah, Qasim, Shah, Sarfaraz H, Shah, Snehal, Shah, Suraj, Shah, Syed, Shah, Wajid, Shahad, Saarma, Shahi, Sousan, Shahnazari, Sipan, Shahzeb, Muhammad, Shaibu, Aisha, Shaida, Zara, Shaikh, Amina Y, Shaikh, Maliha, Shail, Rajit, Shaji, Mariya, Shakeel, Muhammad, Shalan, Korah, Shamim, Nadia, Shams, Kazi, Shanahan, Thomas, Sharaf, Hamed, Sharif, Asir, Sharma, Ajay, Sharma, Ash, Sharma, Bhawna, Sharma, Mona, Sharma, Ojasvi, Sharma, Poonam, Sharma, Rajeev, Sharma, Sanjeev, Sharma, Sarkhara, Sharma, Shriv, Sharma, Sonal, Sharp, Alexander, Sharp, Charles, Sharp, Gemma, Sharratt, Paula, Sharratt, Phoebe, Sharrocks, Katherine, Shashaa, Serene, Shaw, Christopher, Shaw, Daisy, Shaw, David, Shaw, Deborah, Shaw, Joanne, Shaw, Jonathon, Shaw, Lisa, Shaw, Tomos G, Shawcross, Anna, Shawe, Jill, Shayler, Lou, Shedwell, Sophy, Sheffield, Jonathan, Shehata, Zak, Sheik, Arshiya, Sheikh, Asif, Sheikh, Noorann, Shelley, Benjamin, Shelton, Sarah, Shenoy, Anil, Shenton, Julie, Shepherd, Amy, Shepherd, Kate, Shepherd, Lorna, Shepherd, Scott, Sheppeard, Rhian, Sheridan, Helen, Sheridan, Ray, Sherridan, Samuel, Sherris, Leanne, Sherwin, Susanna, Shibly, Shaad, Shioi, Chiaki, Shirgaonkar, Anand, Shirley, Kim, Shonubi, Adebusola, Shortman, Rob, Shotton, Rohan, Shotton, Sarah, Shpuza, Ervin, Shrestha, Anil, Shrestha, Apurba, Shrestha, Nora, Shrestha, Suchita, Shuker, Karen, Shurmer, Jack, Siame, Gilbert, Siamia, Loria, Siddavaram, Seshnag, Siddique, Nasir, Siddique, Sohail, Sikondari, Nyma, Silva Moniz, Claudia, Sim, Malcolm, Simangan, Theresa, Simbi, Vimbai, Sime, Robert, Simmons, Oliver, Simms, Richard, Simon, Merritt, Simon, Natalie, Simpson, Angela, Simpson, Anna, Simpson, Danny, Simpson, Georgina, Simpson, Joanne, Simpson, Kerry, Simpson, Phillip, Simpson, Thomas, Simpson, Kathryn, Sing, Cindy, Singh, Ankita, Singh, Claire, Singh, Jayaprakash, Singh, Jyoti, Singh, Lokeshwar, Singh, Manjeet, Singh, Nadira, Singh, Pankaj, Singh, Prabhsimran, Singh, Salil, Singh, Saurabh, Singhal, Parag, Singizi, Bryan, Sinha, Manas, Sinha, Utkarsh, Sisson, Guy, Sithiravel, Sarah, Sivakumar, Karthikadevi, Sivakumar, Shanmugasundaram, Sivakumran, Darsh, Sivanadarajah, Sivanthi, Sivasothy, Pasupathy-Rajah, Skehan, Nicole, Skelly, Robert, Skelton, Orlagh, Skene, Imogen, Skinner, Denise, Skinner, Tabitha, Skinner, Victoria, Skorko, Agnieszka, Skorupinska, Iwona, Skorupinska, Mariola, Slack, Amy, Slack, Katie, Slack, Wendy, Slade, Heather, Slade, Mark, Slater, Lynda, Slawson, Nicola, Sloan, Andrew, Sloan, Brendan, Sloan, Derek, Sloane, Geraldine, Small, Benjamin, Small, Ellen, Small, Samuel, Smalls, Dawn, Smallshaw, Karen D, Smallwood, Andy, Smit, Carien, Smith, Aileen, Smith, Alex, Smith, Amanda, Smith, Amy, Smith, Andrew, Smith, Catherine, Smith, Chris, Smith, Christopher, Smith, Dominic, Smith, Eleanor, Smith, Harriet, Smith, Hazel, Smith, Helen, Smith, Jacky, Smith, Jessica, Smith, Kate, Smith, Kerry, Smith, Lara, Smith, Linda, Smith, Lisa, Smith, Loren, Smith, Maria, Smith, Mel, Smith, Oliver, Smith, Rachel, Smith, Rebecca, Smith, Richard, Smith, Sally, Smith, Samantha, Smith, Stacey, Smith, Stephanie, Smith, Susan, Smith, Imogen, Smith, John, Smolen, Sue, Smuts, Sara, Smyth, Naoise, Snell, Annette, Snell, David, Snell, Luke, So, Beng, Soan, Michelle, Sobande, Toluleyi, Sobrino Diaz, Alberto, Sohail, Basit, Sohail, Bina, Sohal, Herminder, Soiza, Roy, Solademi, Olajumoke, Soleimani, Babak, Solesbury, Amanda, Solly, Reanne, Solomon, Louise, Somalanka, Subash, Somashekar, Chandrashekaraiah, Sonia, Raj, Soo, Shiu-Ching, Soor, Pavandeep, Soothill, Germanda, Soren, Jennifer, Sothinathan, Apina, Sothirajah, Pragalathan, Soussi, Najwa, Southam, Donna, Southern, David, Southern, Iain, Southern, Louise, Southin, Sara M, Southwell, Jessica, Southworth, Thomas, Sowter, Jason, Spalding, Claudia, Spata, Enti, Spears, Katie, Spears, Mark, Spence, Michelle, Spencer, Branwell, Spencer, Gisele, Spencer, Sue, Spencer, Tom, Spickett, Helen, Spillane, Jennifer, Spiller, William, Spinks, Kerry, Spinks, Michelle, Spittle, Nick, Spriggs, Janet, Spring, Oliver, Squires, Gemma, Squires, Jack, Squires, Rebecca, Sreenivasan, Ram, Sreenivasan, Shiva, Sri Paranthamen, K, Srinivasan, Ramesh, Srirajamadhuveeti, Asha, Srirathan, Vino, Stacpoole, Sybil, Stadon, Louise, Staines, Jocasta, Staines, Nikki, Stammers, Katie, Stanciu, Roxana, Stanczuk, Grazyna, Staples, Robyn, Stapley, Simon, Staplin, Natalie, Stark, Adam, Starr, Michelle, Stead, Rached, Steele, Conor, Steer, John, Stefania, Vergnano, Stefanowska, Paula, Stemp, Caroline, Stephens, Alison, Stephensen, David, Stephenson, Elaine, Sterrenburg, Monique, Stevens, Melanie, Stevens, Will, Stevenson, Amy, Stevenson, Andrew, Stevenson, Lesley, Stevenson, Sarah, Steward, Matthew, Stewart, Claire, Stewart, Colin, Stewart, McKenna, Stewart, Rachel, Stewart, Richard, Stickley, Jo, Stiller, Gemma, Stirrup, Sarah, Stock, Sarah, Stockdale, Alexander, Stockham, Lynne, Stockton, Paul, Stoddard, Emma, Stokes, Chris, Stone, Ben, Stone, Roisin, Stone, Sarah, Storey, Imogen, Storton, Kim, Stourton, Frederick, Strachan, Angela, Strait, Catherine, Stratton, Emma, Stratton, Jane, Straw, Sam, Streit, Dieter, Stride, Emma, Stringer, Sally, Strong-Sheldrake, Sophia, Struik, Siske, Stuart, Carmel, Stubbs, Anna, Stubbs, Harrison, Sturdy, Ann, Sturney, Sharon, Stuttard, Matt, Suarez, Cristina, Subba, Karuna, Subbe, Christian P, Subramanian, Manjula, Subramanian, Venkatram, Subudhi, Chinari, Suckling, Rebecca, Sudershan, Srivatsan, Sugden, Peter, Sukla, Rudresh, Suliman, Ali, Suliman, Fatimah, Sultan, Sugrah, Sundar, Samyukta, Sundhar, Reka, Sung, Edmond, Sunni, Nadia, Suntharalingam, Jay, Sur, Amitava, Suresh, Dharmic, Suresh, Shilpa, Surtees, Michael, Susan, C, Suter, Danielle, Sutherland, Helen, Sutherland, Rachel, Sutherland, Rebecca, Sutinyte, Dovile, Sutton, Deborah, Sutton, Sam, Sutu, Mihaela, Svensson, Marie-Louise, Svirpliene, Sima, Swain, Andrew, Swain, Rose, Swaine, Thomas, Swales, Christopher, Swart, Tirion, Sweetman, Stephen, Sweity, Samaher, Swift, Ealish, Swift, Paul, Swift, Pauline, Swift, Rachael, Swingler, Rachel, Swinhoe, Sophie, Swist-Szulik, Katarzyna, Swithenbank, Luke, Syed, Omair, Sykes, Catriona, Sykes, Daisy, Sykes, Eliot, Sylvester, Luke, Symon, Dominic, Syndercombe, Andrew, Syrimi, Zoe, Syson, Jen, Szabo, Gemma, Szakmany, Tamas, Szekely, Megan, Szeto, Matthew, Tadros, Maria, Tageldin, Amr, Tague, Lucy, Tahir, Hasan, Tahir, Muhammad, Takyi, Abigail, Talbot, Peter, Talbot -Smith, Alison, Talbot-Ponsonby, James, Tallent, Richard, Tallon, Bradley, Tamblin-Hopper, Phoebe, Tan, Adrian, Tan, Bee Theng, Tan, Hock, Tan, Huey, Tan, Keith, Tan, WeiTeen, Tana, Anand, Tanney, Christina, Tanqueray, Tabitha, Tanton, Emma, Tantri, Anita, Tarft, Hayley, Tarft, Hayley, Taribagil, Priyal, Tarin, Obaid, Tariq, Syed, Tarpey, David, Tarrant, Lisa, Tasiou, Antonia, Tate, Margaret L, Tatham, Kate, Tavoukjian, Vera, Taylor, Alexander, Taylor, Beverley, Taylor, Charlie, Taylor, David, Taylor, Elisabeth, Taylor, Janet, Taylor, Jennifer, Taylor, Joanne, Taylor, Julie, Taylor, Karen, Taylor, Leanne, Taylor, Margaret, Taylor, Matthew, Taylor, Melanie, Taylor, Natalie, Taylor, Rachael, Taylor, Rachel, Taylor, Samantha, Taylor, Suzanne, Taylor, Tracey, Taylor, Vicky, Taylor-Siddons, Michelle, Taynton, Thomas, Te, Amelia, Teasdale, Jessica, Tebbutt, Julie, Tee, Caroline, Tejwani, Rajni, Telfer, Adam, Teli, Vibha, Tempany, Jennifer, Temple, Julie, Temple, Natalie, Tench, Helen, Teoh, Yi He, Terrett, Lynne, Terry, Louise, Tetla, Dariusz, Tewari, Shirish, Tewkesbury, Daniel, Texeira, Joana, Tey, ChiaLing, Thakker, Clare, Thakker, Manish, Thatcher, Hilary, Thayanandan, Andrew, Thazhatheyil, Krishna, Thein, Eaint, Theocharidou, Lambrini, Thet, Phyu, Thevarajah, Kapeendran, Thevendra, Mayooran, Thiri Phoo, Nang, Thirlwall, Yvette, Thirumaran, Muthu, Thomas, 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Nalini, Vinod W, Vilcinskaite, Brigita, Vilimiene, Neringa, Vinall, Lynn, Vinay, Sylvia, Vinayakarao, Latha, Vincent, Rachel, Vincent, Rosie, Virdee, Pritpal, Virgilio, Emma, Virk, Abdullah M, Visentin, Elisa, Vithian, Karunakaran, Vittoria, Sorice, Vlad, Elena, Vlies, Ben, Vuylsteke, Alain, Vyras, Eleftheria, Wach, Richard, Wadams, Beverley, Wadd, Susan, Waddington, Natalia, Wade, Phillip, Wadsworth, Kirsten, Wafa, Syed E I, Wagstaff, Daniel, Wagstaff, Lynda, Wahab, Dalia, Wahbi, Zaroug, Waheed Adigun, Abiodun, Waidyanatha, Sawan, Wake, Rachel, Wakefield, Alice, Wakeford, William, Wakinshaw, Fiona, Walden, Andrew, Walding, Lorna, Waldron, Alexandria, Walker, Gemma, Walker, Harriet, Walker, Ian, Walker, Kevin, Walker, Kim, Walker, Linda, Walker, Olivia, Walker, Rachel, Walker, Rebecca, Walker, Susan, Wallbutton, Rebecca, Wallen, Jessica, Wallendszus, Karl, Waller, Arabella, Waller, Rosemary, Wallis, Gabiel, Wallis, Gabriel, Wallis, Louise, Walsh, Donna, Walsh, Elizabeth, Walsh, Livia, 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Christopher, Woollen, Louisa, Woolley, Emma, Woolley, Jade, Woosey, Daniel, Wootton, Dan, Wootton, Joanne, Worley, Daniel, Worton, Stephy, Wraight, Jonathan, Wray, Maria, Wren, Kim, Wren, Lynn, Wrey Brown, Caroline, Wright, Catherine, Wright, Demi, Wright, Francesca, Wright, Imogen, Wright, Lianne, Wright, Rachel, Wright, Stephanie, Wright, Tim, Wroe, Caroline, Wroe, Hannah, Wu, Henry, Wu, Peishan, Wu, Pensee, Wubetu, Jonathan, Wulandari, Fitria, Wulandari, Retno, Wyatt, Craig, Wyn-Griffiths, Frederick, Wynter, Inez, Xavier, Bindhu, Xhikola, Arnold, Xia, Zhongyang, Xiao, Huiyuan, Yakubi, Masseh, Yan, May, Yang, Freda, Yang, Yingjia, Yanney, Michael, Yap, Woei Lin, Yaqoob, Nabil, Yasmin, Salima, Yates, Bryan, Yates, David, Yates, Edward, Yates, Helen, Yates, Thomas, Yates, Mark, Yearwood Martin, Charlotte, Yein, Khin, Yelnoorkar, Fiona, Yew, Peter, Ylquimiche, Laura, Ylquimiche Melly, Laura, Ynter, Inez, Yong, H, Yorke, Jemma, Youens, Jasmine, Younes Ibrahim, Abdel, Young, Eoin, Young, Gail, Young, Louise, Yousafzar, Asfand, Youssouf, Sajeda, Yousuf, Ahmed, Yu, Chrissie, Yung, Bernard, Yusef, Daniel, Yusef, Said, Yusuf, Intekhab, Zafar, Anna-Sophia, Zagalo, Silvia, Zaher, Su, Zahoor, Aqsa, Zaki, Kareem, Zakir, Nabhan, Zalewska, Kasia, Zamalloa, Ane, Zaman, Mohsin, Zaman, Shakir, Zamikula, Julie, Zammit, Louise, Zammit-Mangion, Marie, Zebracki, Esther, Zehnder, Daniel, Zeidan, Lisa, Zhao, Xiaobei, Zheng, Dongling, Zhu, Doreen, Zia, Madiha, Zibdeh, Omar, Zill-E-Huma, Rabia, Zin, Ei Thankt, Zinkin, Eleanor, Zinyemba, Vivian, Zipitis, Christos, Zmierczak, Arkadiusz, Zubir, Azam, Zuhra, Naz, Zulaikha, Rasha, Zulfikar, Sabrina, Zullo, Carol, Zuriaga-Alvaro, Ana, and Zyengi, Sheba
- The Lancet; February 2022, Vol. 399 Issue: 10325 p665-676, 12p
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Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. We aimed to evaluate the efficacy and safety of casirivimab and imdevimab administered in combination in patients admitted to hospital with COVID-19.
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Polizzotto, Mark N., Nordwall, Jacqueline, Babiker, Abdel G., Phillips, Andrew, Vock, David M., Eriobu, Nnakelu, Kwaghe, Vivian, Paredes, Roger, Mateu, Lourdes, Ramachandruni, Srikanth, Narang, Rajeev, Jain, Mamta K., Lazarte, Susana M., Baker, Jason V., Frosch, Anne E.P., Poulakou, Garyfallia, Syrigos, Konstantinos N., Arnoczy, Gretchen S., McBride, Natalie A., Robinson, Philip A., Sarafian, Farjad, Bhagani, Sanjay, Taha, Hassan S., Benfield, Thomas, Liu, Sean T.H., Antoniadou, Anastasia, Jensen, Jens Ulrik Stæhr, Kalomenidis, Ioannis, Susilo, Adityo, Hariadi, Prasetyo, Jensen MD, Tomas O., Morales-Rull, Jose Luis, Helleberg, Marie, Meegada, Sreenath, Johansen, Isik S., Canario, Daniel, Fernández-Cruz, Eduardo, Metallidis, Simeon, Shah, Amish, Sakurai, Aki, Koulouris, Nikolaos G., Trotman, Robin, Weintrob, Amy C., Podlekareva, Daria, Hadi, Usman, Lloyd, Kathryn M., Røge, Birgit Thorup, Saito, Sho, Sweerus, Kelly, Malin, Jakob J., Lübbert, Christoph, Muñoz, Jose, Cummings, Matthew J., Losso, Marcelo H., Turner, Dan, Shaw-Saliba, Kathryn, Dewar, Robin, Highbarger, Helene, Lallemand, Perrine, Rehman, Tauseef, Gerry, Norman, Arlinda, Dona, Chang, Christina C., Grund, Birgit, Holbrook, Michael R., Holley, Horace P., Hudson, Fleur, McNay, Laura A., Murray, Daniel D., Pett, Sarah L., Shaughnessy, Megan, Smolskis, Mary C., Touloumi, Giota, Wright, Mary E., Doyle, Mittie K., Popik, Sharon, Hall, Christine, Ramanathan, Roshan, Cao, Huyen, Mondou, Elsa, Willis, Todd, Thakuria, Joseph V., Yel, Leman, Higgs, Elizabeth, Kan, Virginia L., Lundgren, Jens D., Neaton, James D., and Lane, H. Clifford
- The Lancet; February 2022, Vol. 399 Issue: 10324 p530-540, 11p
- Abstract
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Passive immunotherapy using hyperimmune intravenous immunoglobulin (hIVIG) to SARS-CoV-2, derived from recovered donors, is a potential rapidly available, specific therapy for an outbreak infection such as SARS-CoV-2. Findings from randomised clinical trials of hIVIG for the treatment of COVID-19 are limited.
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Chang A, Alejo JL, Abedon AT, Mitchell J, Chiang TP, Boyarsky BJ, Avery RK, Tobian AAR, Levan ML, Warren DS, Massie AB, Garonzik-Wang JM, Segev DL, and Werbel WA
Transplantation [Transplantation] 2022 Feb 01; Vol. 106 (2), pp. e161-e162.
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Adult, Aged, Female, Humans, Male, Middle Aged, RNA, Messenger genetics, SARS-CoV-2 genetics, SARS-CoV-2 isolation purification, Vaccination adverse effects, Antibody Formation, COVID-19 prevention control, COVID-19 Vaccines administration dosage, Organ Transplantation adverse effects, and Transplant Recipients
- Abstract
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Competing Interests: Dr Segev has the following financial disclosures: consulting and speaking honoraria from Sanofi, Novartis, CLS Behring, Jazz Pharmaceuticals, Veloxis, Mallinckrodt, and Thermo Fisher Scientific. Dr Avery has study/grant support from Aicuris, Astellas, Chimerix, Merck, Oxford Immunotec, Qiagen, Regeneron, Takeda/Shire, and Vir/GSK, and is an associate editor for Transplantation. Dr Levan is the Social Media Editor for Transplantation. The other authors declare no conflicts of interest.
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Rochette A, Roberge-Dao J, Roche L, Kehayia E, Ménard L, Robin JP, Sauvé M, Shikako-Thomas K, St-Onge M, Swaine B, Thomas A, Vallée-Dumas C, and Fougeyrollas P
Patient education and counseling [Patient Educ Couns] 2022 Feb; Vol. 105 (2), pp. 416-425. Date of Electronic Publication: 2021 May 23.
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Canada, Humans, Quebec, Research Personnel, Disabled Persons, and Social Inclusion
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Objective: The main objectives were to 1) search and map current disability awareness and training activities in Quebec, Canada, 2) collectively reflect on these practices, and 3) develop a five-year strategic plan.
Methods: We used an integrated knowledge translation approach whereby researchers and community partners were involved in all stages. This project consisted of two sequential phases: 1) an environmental scan (web review and interview) of current practices, and 2) a reflection process with an external expert-facilitator in social transformation. Outcome results and process data are reported.
Results: We identified 129 activities (71 training, 58 awareness) from 39 organizations (from 123 organizations initially invited). A wide range of characteristics were collected for each activity which allowed for the identification of gaps. The working group met seven times in one year to discuss results from phase 1 and co-create a five-year strategic plan. Main priorities are 1) the development of a methodology for measuring collective impact and 2) content synchronization of activities.
Conclusion: Involvement of partners and researchers enabled a concerted and efficient approach to the development of a five-year strategic plan.
Practice Implications: A transition committee led by partners will ensure implementation and sustainability of the plan across the province.
(Copyright © 2021 Elsevier B.V. All rights reserved.)
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Stapley, Rachel J., Poulter, Natalie S., Khan, Abdullah O., Smith, Christopher W., Bignell, Patricia, Fratter, Carl, Lester, Will, Lowe, Gillian, Morgan, Neil V., Morgan, Neil V., Morgan, Neil, Watson, Steve, Harrison, Paul, Lordkipanidze, Marie, Mumford, Andrew D., Mundell, Stuart J., Gissen, Paul, Daly, Martina E., Clark, Justin, Williams, Mike, Motwani, Jayashree, Marshall, Dianne, Lawson, Natalie, Nyatanga, Priscilla, Mann, Pat, Kirwan, Julie, Percy, Charles, Green, Pam, Hupston, Helen, Nagapachetty, Koomaravel, Dwenger, Elizabeth, Rourke, Ann O, Pope, Martin, Edmead, Camillia, Greenway, April, Makris, Michael, Payne, Jeanette, Pavord, Sue, Gooding, Richard, Dattani, Rashesh, Grimley, Gerry Dolan, Charlotte, Stokley, Simone, Astwood, Emma, Longmuir, Karyn, Chang, Cherry, Foros, Merri, Kightley, Michelle, Trower, Linda, Thachil, Jecko, Bolton Maggs, Paula, Hay, Charlie, Pike, Gill, Will, Andrew, Grainger, John, Foulkes, Matt, Fareh, Mona, Talks, Kate, Biss, Tina, Kesteven, Patrick, Hanley, John, Vowles, Julie, Basey, Lesley, Knaggs, Kevin, Barnes, Michelle, Collins, Peter, Rayment, Rachel, Alikhan, Raza, Rebecca Morris, Ana Guerrero, Mansell, Dianne, Toh, Cheng Hock, Martlew, Vanessa, Murphy, Elaine, Lachmann, Robin, Rose, Peter, Chapman, Oliver, Lokare, Anand, Marshall, Kathryn, Khan, Naseem, Keeling, David, Curry, Nikki, Giangrande, Paul, Austin, Steve, Bevan, David, Alamelu, Jayanthi, Allsup, David, Fletcher, Andrew, Gladstone, Katherine, Fenwick, Jeanette, Woods, Philippa, Camp, Darren, James, Beki, Preston, Suzie, Spencer, Collette, Pike, Alexandra, Lai-Wah, Chung, Thomas, Angela, Myers, Bethan, Evans, Gillian, Elliot, Kim, Davies, Karen, Graham, Charlotte, Foad, Miranda, Smith, Jacqueline, and Morgan, Neil
- Journal of Thrombosis and Haemostasis. February, 2022, Vol. 20 Issue 2, p478, 8 p.
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81. In Our Mailbox. [2022]
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Darvell, Deborah, Volzer, Alyx, Watkins, Rachel E., Arwen, Shanti, Whitaker-Brown, Lynne, Loftus, Kathryn Susanne, Anne, Jacqueline, Michaelides, Theodoros, Bellantoni Anderson, Robin, and Weintraub, David
- Massage Magazine; Feb2022, Issue 309, p14-14, 1p
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NARCOTICS, MASSAGE therapy, COVID-19, ANALGESICS, CLIENT relations, POSTAL service, POSTURE, and EMOTIONS
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Patterson, Nick, Isakov, Michael, Booth, Thomas, Büster, Lindsey, Fischer, Claire-Elise, Olalde, Iñigo, Ringbauer, Harald, Akbari, Ali, Cheronet, Olivia, Bleasdale, Madeleine, Adamski, Nicole, Altena, Eveline, Bernardos, Rebecca, Brace, Selina, Broomandkhoshbacht, Nasreen, Callan, Kimberly, Candilio, Francesca, Culleton, Brendan, Curtis, Elizabeth, Demetz, Lea, Carlson, Kellie Sara Duffett, Edwards, Ceiridwen J., Fernandes, Daniel M., Foody, M. George B., Freilich, Suzanne, Goodchild, Helen, Kearns, Aisling, Lawson, Ann Marie, Lazaridis, Iosif, Mah, Matthew, Mallick, Swapan, Mandl, Kirsten, Micco, Adam, Michel, Megan, Morante, Guillermo Bravo, Oppenheimer, Jonas, Özdoğan, Kadir Toykan, Qiu, Lijun, Schattke, Constanze, Stewardson, Kristin, Workman, J. Noah, Zalzala, Fatma, Zhang, Zhao, Agustí, Bibiana, Allen, Tim, Almássy, Katalin, Amkreutz, Luc, Ash, Abigail, Baillif-Ducros, Christèle, Barclay, Alistair, Bartosiewicz, László, Baxter, Katherine, Bernert, Zsolt, Blažek, Jan, Bodružić, Mario, Boissinot, Philippe, Bonsall, Clive, Bradley, Pippa, Brittain, Marcus, Brookes, Alison, Brown, Fraser, Brown, Lisa, Brunning, Richard, Budd, Chelsea, Burmaz, Josip, Canet, Sylvain, Carnicero-Cáceres, Silvia, Čaušević-Bully, Morana, Chamberlain, Andrew, Chauvin, Sébastien, Clough, Sharon, Čondić, Natalija, Coppa, Alfredo, Craig, Oliver, Črešnar, Matija, Cummings, Vicki, Czifra, Szabolcs, Danielisová, Alžběta, Daniels, Robin, Davies, Alex, de Jersey, Philip, Deacon, Jody, Deminger, Csilla, Ditchfield, Peter W., Dizdar, Marko, Dobeš, Miroslav, Dobisíková, Miluše, Domboróczki, László, Drinkall, Gail, Đukić, Ana, Ernée, Michal, Evans, Christopher, Evans, Jane, Fernández-Götz, Manuel, Filipović, Slavica, Fitzpatrick, Andrew, Fokkens, Harry, Fowler, Chris, Fox, Allison, Gallina, Zsolt, Gamble, Michelle, González Morales, Manuel R., González-Rabanal, Borja, Green, Adrian, Gyenesei, Katalin, Habermehl, Diederick, Hajdu, Tamás, Hamilton, Derek, Harris, James, Hayden, Chris, Hendriks, Joep, Hernu, Bénédicte, Hey, Gill, Horňák, Milan, Ilon, Gábor, Istvánovits, Eszter, Jones, Andy M., Kavur, Martina Blečić, Kazek, Kevin, Kenyon, Robert A., Khreisheh, Amal, Kiss, Viktória, Kleijne, Jos, Knight, Mark, Kootker, Lisette M., Kovács, Péter F., Kozubová, Anita, Kulcsár, Gabriella, Kulcsár, Valéria, Le Pennec, Christophe, Legge, Michael, Leivers, Matt, Loe, Louise, López-Costas, Olalla, Lord, Tom, Los, Dženi, Lyall, James, Marín-Arroyo, Ana B., Mason, Philip, Matošević, Damir, Maxted, Andy, McIntyre, Lauren, McKinley, Jacqueline, McSweeney, Kathleen, Meijlink, Bernard, Mende, Balázs G., Menđušić, Marko, Metlička, Milan, Meyer, Sophie, Mihovilić, Kristina, Milasinovic, Lidija, Minnitt, Steve, Moore, Joanna, Morley, Geoff, Mullan, Graham, Musilová, Margaréta, Neil, Benjamin, Nicholls, Rebecca, Novak, Mario, Pala, Maria, Papworth, Martin, Paresys, Cécile, Patten, Ricky, Perkić, Domagoj, Pesti, Krisztina, Petit, Alba, Petriščáková, Katarína, Pichon, Coline, Pickard, Catriona, Pilling, Zoltán, Price, T. Douglas, Radović, Siniša, Redfern, Rebecca, Resutík, Branislav, Rhodes, Daniel T., Richards, Martin B., Roberts, Amy, Roefstra, Jean, Sankot, Pavel, Šefčáková, Alena, Sheridan, Alison, Skae, Sabine, Šmolíková, Miroslava, Somogyi, Krisztina, Somogyvári, Ágnes, Stephens, Mark, Szabó, Géza, Szécsényi-Nagy, Anna, Szeniczey, Tamás, Tabor, Jonathan, Tankó, Károly, Maria, Clenis Tavarez, Terry, Rachel, Teržan, Biba, Teschler-Nicola, Maria, Torres-Martínez, Jesús F., Trapp, Julien, Turle, Ross, Ujvári, Ferenc, van der Heiden, Menno, Veleminsky, Petr, Veselka, Barbara, Vytlačil, Zdeněk, Waddington, Clive, Ware, Paula, Wilkinson, Paul, Wilson, Linda, Wiseman, Rob, Young, Eilidh, Zaninović, Joško, Žitňan, Andrej, Lalueza-Fox, Carles, de Knijff, Peter, Barnes, Ian, Halkon, Peter, Thomas, Mark G., Kennett, Douglas J., Cunliffe, Barry, Lillie, Malcolm, Rohland, Nadin, Pinhasi, Ron, Armit, Ian, and Reich, David
- Nature; January 2022, Vol. 601 Issue: 7894 p588-594, 7p
- Abstract
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Present-day people from England and Wales have more ancestry derived from early European farmers (EEF) than did people of the Early Bronze Age1. To understand this, here we generated genome-wide data from 793 individuals, increasing data from the Middle to the Late Bronze Age and Iron Age in Britain by 12-fold, and western and central Europe by 3.5-fold. Between 1000 and 875 bc, EEF ancestry increased in southern Britain (England and Wales) but not northern Britain (Scotland) due to incorporation of migrants who arrived at this time and over previous centuries, and who were genetically most similar to ancient individuals from France. These migrants contributed about half the ancestry of people of England and Wales from the Iron Age, thereby creating a plausible vector for the spread of early Celtic languages into Britain. These patterns are part of a broader trend of EEF ancestry becoming more similar across central and western Europe in the Middle to the Late Bronze Age, coincident with archaeological evidence of intensified cultural exchange2–6. There was comparatively less gene flow from continental Europe during the Iron Age, and the independent genetic trajectory in Britain is also reflected in the rise of the allele conferring lactase persistence to approximately 50% by this time compared to approximately 7% in central Europe where it rose rapidly in frequency only a millennium later. This suggests that dairy products were used in qualitatively different ways in Britain and in central Europe over this period.
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Barnes DR, Silvestri V, Leslie G, McGuffog L, Dennis J, Yang X, Adlard J, Agnarsson BA, Ahmed M, Aittomäki K, Andrulis IL, Arason A, Arnold N, Auber B, Azzollini J, Balmaña J, Barkardottir RB, Barrowdale D, Barwell J, Belotti M, Benitez J, Berthet P, Boonen SE, Borg Å, Bozsik A, Brady AF, Brennan P, Brewer C, Brunet J, Bucalo A, Buys SS, Caldés T, Caligo MA, Campbell I, Cassingham H, Christensen LL, Cini G, Claes KBM, Cook J, Coppa A, Cortesi L, Damante G, Darder E, Davidson R, de la Hoya M, De Leeneer K, de Putter R, Del Valle J, Diez O, Ding YC, Domchek SM, Donaldson A, Eason J, Eeles R, Engel C, Evans DG, Feliubadaló L, Fostira F, Frone M, Frost D, Gallagher D, Gehrig A, Giraud S, Glendon G, Godwin AK, Goldgar DE, Greene MH, Gregory H, Gross E, Hahnen E, Hamann U, Hansen TVO, Hanson H, Hentschel J, Horvath J, Izatt L, Izquierdo A, James PA, Janavicius R, Jensen UB, Johannsson OT, John EM, Kramer G, Kroeldrup L, Kruse TA, Lautrup C, Lazaro C, Lesueur F, Lopez-Fernández A, Mai PL, Manoukian S, Matrai Z, Matricardi L, Maxwell KN, Mebirouk N, Meindl A, Montagna M, Monteiro AN, Morrison PJ, Muranen TA, Murray A, Nathanson KL, Neuhausen SL, Nevanlinna H, Nguyen-Dumont T, Niederacher D, Olah E, Olopade OI, Palli D, Parsons MT, Pedersen IS, Peissel B, Perez-Segura P, Peterlongo P, Petersen AH, Pinto P, Porteous ME, Pottinger C, Pujana MA, Radice P, Ramser J, Rantala J, Robson M, Rogers MT, Rønlund K, Rump A, Sánchez de Abajo AM, Shah PD, Sharif S, Side LE, Singer CF, Stadler Z, Steele L, Stoppa-Lyonnet D, Sutter C, Tan YY, Teixeira MR, Teulé A, Thull DL, Tischkowitz M, Toland AE, Tommasi S, Toss A, Trainer AH, Tripathi V, Valentini V, van Asperen CJ, Venturelli M, Viel A, Vijai J, Walker L, Wang-Gohrke S, Wappenschmidt B, Whaite A, Zanna I, Offit K, Thomassen M, Couch FJ, Schmutzler RK, Simard J, Easton DF, Chenevix-Trench G, Antoniou AC, and Ottini L
Journal of the National Cancer Institute [J Natl Cancer Inst] 2022 Jan 11; Vol. 114 (1), pp. 109-122.
- Subjects
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Aged, 80 and over, BRCA1 Protein genetics, BRCA2 Protein genetics, Genetic Predisposition to Disease, Heterozygote, Humans, Male, Mutation, Polymorphism, Single Nucleotide, Risk Assessment, Risk Factors, Breast Neoplasms epidemiology, Breast Neoplasms genetics, Prostatic Neoplasms epidemiology, and Prostatic Neoplasms genetics
- Abstract
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Background: Recent population-based female breast cancer and prostate cancer polygenic risk scores (PRS) have been developed. We assessed the associations of these PRS with breast and prostate cancer risks for male BRCA1 and BRCA2 pathogenic variant carriers.
Methods: 483 BRCA1 and 1318 BRCA2 European ancestry male carriers were available from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). A 147-single nucleotide polymorphism (SNP) prostate cancer PRS (PRSPC) and a 313-SNP breast cancer PRS were evaluated. There were 3 versions of the breast cancer PRS, optimized to predict overall (PRSBC), estrogen receptor (ER)-negative (PRSER-), or ER-positive (PRSER+) breast cancer risk.
Results: PRSER+ yielded the strongest association with breast cancer risk. The odds ratios (ORs) per PRSER+ standard deviation estimates were 1.40 (95% confidence interval [CI] =1.07 to 1.83) for BRCA1 and 1.33 (95% CI = 1.16 to 1.52) for BRCA2 carriers. PRSPC was associated with prostate cancer risk for BRCA1 (OR = 1.73, 95% CI = 1.28 to 2.33) and BRCA2 (OR = 1.60, 95% CI = 1.34 to 1.91) carriers. The estimated breast cancer odds ratios were larger after adjusting for female relative breast cancer family history. By age 85 years, for BRCA2 carriers, the breast cancer risk varied from 7.7% to 18.4% and prostate cancer risk from 34.1% to 87.6% between the 5th and 95th percentiles of the PRS distributions.
Conclusions: Population-based prostate and female breast cancer PRS are associated with a wide range of absolute breast and prostate cancer risks for male BRCA1 and BRCA2 carriers. These findings warrant further investigation aimed at providing personalized cancer risks for male carriers and informing clinical management.
(© The Author(s) 2021. Published by Oxford University Press.)
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Abani, Obbina, Abbas, Ali, Abbas, Fatima, Abbas, Mustafa, Abbasi, Sadia, Abbass, Hakam, Abbott, Alfie, Abdallah, Nabeel, Abdelaziz, Ashraf, Abdelfattah, Mohamed, Abdelqader, Bushra, Abdul, Basir, Abdul Rasheed, Althaf, Abdulakeem, Ajibode, Abdul-Kadir, Rezan, Abdullah, Abdullah, Abdulmumeen, Abdulfatahi, Abdul-Raheem, Rasheed, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Abeer Ul Amna, Abeer Ul Amna, Abernethy, Katrina, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abraham, Miriam, Abraham, Tizzy, Abraheem, Abraheem, Abrams, Judith, Abu, Hyacinth-John, Abu-Arafeh, Ahmed, Abubacker, Syed Mohamed, Abung, Akata, Aceampong, Yaa, Achara, Amaka, Acharya, Devikumar, Acheampong, Sarah, Acheson, Janet, Acosta, Andres, Acton, Catherine, Adabie-Ankrah, Jacqueline, Adam, Fiona, Adam, Matthew, Adamali, Huzaifa, Adams, Carol, Adams, Charlotte, Adams, Kate, Adams, Richard, Adams, Tim, Adcock, Kirsty, Adebiyi, Ade, Adegoke, Ken, Adell, Vicki, Adenwalla, Sherna, Adesemoye, Oluwasegun A, Adewunmi, Emmanuel O, Adeyemi, Joyce, Adhikari, Binay, Adhikary, Rina, Adkins, Gabrielle, Adnan, Adnan, Aeron-Thomas, John, Affleck, Debbie, Afnan, Carmel, Afridi, Muhammad, Aftab, Zainab A, Agarwal, Meenakshi, Agbeko, Rachel, Agbo, Chris, Aggarwal, Sunil, Aghababaie, Arameh, Ahamed Sadiq, Shafana, Ahammed Nazeer, Mohamed H, Ahmad, Mohammad, Ahmad, Syed, Ahmed, Asim, Ahmed, Bilal, Ahmed, Forizuddin, Ahmed, Hamze, Ahmed, Iram, Ahmed, Irshad, Ahmed, Khaled, Ahmed, Liban, Ahmed, Mahin, Ahmed, Maria C, Ahmed, Muhammad S, Ahmed, Naseer, Ahmed, Nausheen, Ahmed, Osama, Ahmed, Rajia A, Ahmed, Rizwan, Ahmed, Saif, Ahmed, Sammiya, Ahmed, Sara, Ahmed, Syed, Ahmed, Syed Haris, Ahmed Ali, Roa, Ahmed, Sana, Ahmer, Sana, Ail, Dhiraj, Ainsworth, Mark, Aissa, Myriam, Aitken, Lindianne, Ajay, Bini, Ajibode, Abdulakeem, Ajmi, Ayesha, Akhtar, Nasim, Akhtar, Nauman, Akili, Suha, Akindolie, Oludoyinsola, Akinfenwa, Yinka, Akinkugbe, Olugbenga, Akinpelu, Ibrahim, Aktinade, Olugbenro, Al Aaraj, Ahmad, Al Balushi, Asma, Al Dakhola, Majd, Al Swaifi, Aladdin, Al-Abadi, Eslam, Aladangady, Narendra, Alam, Ayaz, Alam, Sajid, Al-Asadi, Abbas, Alatzoglou, Kyriaki, Albert, Paul, Albon, Lorraine, Alcorn, Gemma, Alcorn, Stephen, Aldana, Aggie, Alderdice, David, Aldouri, Rayan, Aldridge, Jonathan, Aldridge, Nicolas, Alegria, Ana, Alexander, Alison, Alexander, John, Alexander, Peter D G, Al-Fori, Julyan, Alghazawi, Laith, Al-Hakim, Bahij, Al-Hity, Shams, Ali, Ali, Ali, Asad, Ali, Fawzia R, Ali, Jawad, Ali, Mariam, Ali, Mohammad, Ali, Nayab, Ali, Oudai, Ali, Sakina, Ali, Syed, Alina, Abid, Aliyuda, Fine, Alizadeh, Katrin, Al-Jibury, Maithem, Al-Juboori, Saba, Al-Khalil, Majid, Alkhusheh, Moutaz, Allan, Fiona, Allanson, Alison, Allcock, Robert, Allen, Eireann, Allen, Kerry, Allen, Louise, Allen, Poppy, Allen, Rebecca, Allen, Sam, Allen, Sharon, Allen, Simon, Allison, Kathryn, Allman, Bethan, Allsop, Lynne, Al-Moasseb, Hassan, Al-Obaidi, Magda, Alomari, Lina, Al-Rabahi, Akram, Al-Ramadhani, Bahar, Al-Saadi, Zayneb, Alshaer, Inji, Al-Shahi Salman, Rustam, Al-Shamkhani, Warkaq, Al-Sheklly, Bashar, Altaf, Sara, Alvarez, Mary, Alzetani, Maysaa, Amamou, Susan, Amar, Noor, Ambalavanan, Sakkarai, Ambler, Sarah-Jayne, Ambrogetti, Robert, Ambrose, Chris, Ameen, Amir, Amezaga, Maria R, Amin, Allison, Amin, Amina, Amin, Kanish, Amin, Syed, Amin, Tara, Amjad, Amjad, Amjad, Neelma, Amosun, Victoria, Amsha, Khaled, Amy, Pugh, Anand, Atul, Anandappa, Samantha, Anderson, Julie, Anderson, Laura, Anderson, Michelle, Anderson, Nicola, Anderson, Rachel, Anderson, Rory, Anderson, Wendy, Andreou, Prematie, Andrews, Angela, Andrews, Antonette, Andrews, Jill, Aneke, Kanayochukwu, Ang, Andrew, Ang, Wan Wei, Angel, Tammy, Angela, Aramburo, Angelini, Paola, Anguvaa, Lazarus, Anichtchik, Oleg, Anim-Somuah, Millicent, Aniruddhan, Krishnan, Annett, Jessica, Anstey, Patrick James, Anstey, Rebekah, Anthony, Alpha, Anthony-Pillai, Aaron, Antill, Philip, Antonina, Zhelyazkova, Anu, Varghese, Anwar, Muhammad, Apostolopoulos, Aristeidis, Appleby, Sarah, Appleyard, Diane, Aquino, Maia Far, Araba, Bianca, Aransiola, Samuel, Araujo, Mariana, Archer, Ann, Archer, Denise, Archer, Simon, Ardley, Christian, Arias, Ana-Maria, Arimoto, Ryoki, Arkley, Charlotte, Armah, Charlotte, Armata, Ilianna, Armitage, Adam, Armstrong, Ceri, Armstrong, Maureen, Armstrong, Sonia, Armtrong, Philippa, Arndt, Heike, Arnison-Newgass, Clare, Arnold, David, Arnold, Rachael, Arora, Dhawal, Arora, Kavan, Arora, Pardeep, Arora, Rishi, Arter, Arslam, Arya, Ayush, Arya, Rita, Asandei, Denisa, Asghar, Adeeba, Ashbrook-Raby, Catherine, Ashby, Helen, Ashcroft, Jan, Ashcroft, John, Ashcroft, Samuel, Asher, Georgia, Ashfaq, Ayesha, Ashish, Abdul, Ashman-Flavell, Sally, Ashok, Sundar, Ashour, Abd-El-Aziz, Ashraf, Muhammad Zubair, Ashraf, Saima, Ashraq, Mohammad Bilal, Ashton, Deborah, Ashton, Susan, Ashworth, Andrew, Ashworth, Rebecca, Aslam, Arshia, Asogan, Harshini, Asrar, Atif, Assaf, Omar, Astin-Chamberlain, Raine, Athorne, Deborah, Atkins, Billie, Atkins, Christopher, Atkins, Stacey, Atkinson, John, Atkinson, Vicki, Atraskiewicz, Brygitta, Attia, Abdul Ahmad, Aubrey, Paula, Aujayeb, Avinash, Aung, Aye Chan Thar, Aung, Hnin, Aung, Kyaw Thu, Aung, Yin, Aung, Zaw Myo, Austin, Emily, Austin, Karen, Auwal, Abdusshakur, Avery, Miriam, Aveyard, Nicholas, Avis, Joanne, Aviss, Georgina, Avram, Cristina, Avram, Paula, Awadzi, Gabriel, Awan, Atia, Aya, Aszad, Ayaz, Eman, Ayers, Amanda, Azam, Jawwad, Azharuddin, Mohammed, Aziz, Ghazala, Aziz, N, Azkoul, Ali, Azman Shah, Ashaari, Azzopardi, Giada, Azzoug, Hocine, Babatunde, Fiyinfoluwa, Babi, Melvin, Babiker, Babiker, Babington, Gayna, Babirecki, Matthew, Babores, Marta, Babs-Osibodu, Adetona O, Bacciarelli, Sammy, Bachar, Roudi, Bacon, Gina, Bacon, Jenny, Badal, Bibi, Badhan, Gurpreet Rani, Badhrinarayanan, Shreya, Bae, Joseph P, Baggaley, Alice, Baggott, Amy, Bagley, Graham, Bagmane, Dinesh, Bagshaw, Lynsey, Bahadori, Kasra, Bailey, James, Bailey, Katie, Bailey, Lindsey, Bailey, Liz, Bailey, Morgan, Bailey, Pippa, Bailey, Sarah, Baillie, Hamish, Baillie, J Kenneth, Bain, Jennifer, Bains, Vikram, Baird, David, Baird, Kevin, Baird, Susan, Baird, Tracy, Baird, Yolanda, Bajandouh, Aiysha, Baker, Evelyn, Baker, Johanne, Baker, Josephine, Baker, Kenneth, Baker, Rebecca, Baker, Terri-Anne, Baker, Victoria, Bakere, Hugh, Bakerly, Nawar, Baker-Moffatt, Michelle, Bakhtiar, Nauman, Bakoulas, Panos, Balachandran, Niranjan, Balan, Andrea, Balaskas, Theodosios, Balasubramaniam, Madhu, Balcombe, Alison, Baldwin, Alexander, Baldwin, Ashley, Baldwin, Caron, Baldwin, Danielle, Baldwin-Jones, Rebekah, Balfour, James, Ball, Matthew, Ballard, K, Balluz, Ismael, Balmforth, Craig, Balogh, Emese, Baluwala, Amir, Bambridge, Gabby, Bamford, Alasdair, Bamford, Amy, Bamford, Peter, Bamgboye, Adefunke, Bancroft, Elizabeth, Bancroft, Hollie, Banda, Joyce, Bandaru, Krishna, Bandi, Srini, Bandla, Nageswar, Bandyopadhyam, Somaditya, Banerjee, Amit, Banerjee, Ritwik, Banks, Harrison, Banks, Luke, Banks, Paul, Bannister, Oliver, Banton, Laura, Bao, Tran, Baptist, Mariamma, Baqai, Tanya, Baral, Ananya Mouli, Baramova, Desislava, Barber, Russel, Barbon, Emma, Barbosa, Monica, Barbour, Jamie, Barclay, Alexander, Barclay, Claire, Bardsley, George, Bareford, Stephanie, Bari, Shahedal, Barimbing, Morris, Barker, Amy, Barker, Debbie, Barker, Helen, Barker, Joseph Barker, Barker, Leon, Barker, Oliver, Barker-Williams, Kerry, Barkha, Sinha, Barla, Juliana, Barlow, Gavin, Barlow, Richard, Barlow, Valerie, Barnacle, James, Barnacle, James, Barnard, Alex, Barnes, Debi, Barnes, Nicky, Barnes, Theresa, Barnetson, Calum, Barnett, Amy, Barnett-Vanes, Ashton, Barnsley, William, Barr, Andrew, Barr, David, Barratt, Shaney, Barrera, Manuella, Barrett, Amy, Barrett, Fiona, Barrett, Jessica, Bartholomew, Jazz, Bartlett, Claire, Bartlett, Georgina, Barton, Greg, Barton, Jill, Barton, Lorna, Barton, Rachael, Baruah, Rosaleen, Baryschpolec, Sonia, Bashyal, Archana, Basker, Betsy, Basnyat, Buddha, Basoglu, Ayten, Bassett, John, Bassett, G, Bassford, Chris, Bassoy, Bengisu, Bastion, Victoria, Bastola, Anup, Basumatary, Anupam, Bate, Tristan, Bateman, Harry J, Bateman, Kathryn, Bateman, Vhairi, Bates, Eleanor, Bates, Hayley, Bates, Michelle, Bates, Simon, Batham, Sally, Batista, Ana, Batla, Amit, Batra, Dushyant, Batty, Harry, Batty, Thomas, Baum, Miranda, Baumber, Rachel, Bautista, Carina, Bawa, Fareha, Bawani, Fatima S, Bax, Simon, Baxter, Matt, Baxter, Nicola, Baxter, Zachary, Bayes, Hannah, Bazari, Farid, Bazaz, Rohit, Bazli, Ahmad, Beacham, Laura, Beadles, Wendy, Beak, Philip, Beale, Andy, Bearpark, Jack, Beaumont, Karen, Beaumont-Jewell, Dawn, Beaver, Theresa, Beavis, Sarah, Beazley, Christy, Beck, Sarah, Beckett, Virginia, Beckitt, Rosie, Beddall, Heidi, Beddows, Seonaid, Beeby, Deborah, Beech, Gail, Beecroft, Michelle, Beer, Sally, Beety, Jane, Bega, Gabriela, Begg, Alison, Begg, Susan, Beghini, Sara, Begum, Ayesha, Begum, Salman, Begum, Selina, Behan, Teresa, Behrouzi, Roya, Beishon, Jon, Beith, Claire, Belcher, James, Belfield, Holly, Belfield, Katherine, Belgaumkar, Ajay, Bell, Dina, Bell, Gareth, Bell, Gillian, Bell, Lauren, Bell, Louise, Bell, Nicholas, Bell, Pippa, Bell, Stephanie, Bell, Jennifer L, Bellamu, Jennifer, Bellamy, Mary, Bellini, Arianna, Bellis, Amanda, Bellis, Fionn, Bendall, Lesley, Benesh, Naveena, Benetti, Nicola, Benham, Leonie, Benison-Horner, Guy, Bennett, Ann, Bennett, Caroline, Bennett, Gillian, Bennett, Kristopher, Bennett, Lorraine, Bennett, Sara, Bennion, Karen, Benson, Vivienne, Bentley, Andrew, Bentley, James, Benton, Ian, Beranova, Eva, Beresford, Matthew, Bergin, Colin, Bergstrom, Malin, Bernatoniene, Jolanta, Berriman, Thomas, Berry, Zoe, Best, Kimberley, Bester, Ans-Mari, Beuvink, Yvonne, Bevan, Emily, Bevins, Sarah, Bewick, Tom, Bexley, Andrew, Beyatli, Sonay, Beynon, Fenella, Bhadi, Arjun, Bhagani, Sanjay, Bhakta, Shiv, Bhalla, Rekha, Bhandal, Khushpreet, Bhandal, Kulbinder, Bhandari, Ashwin, Bhandari, Sangam, Bhanot, Aashutosh, Bhanot, Ravina, Bhat, Prashanth, Bhatia, Nikhil, Bhatnagar, Rahul, Bhatt, Karan, Bhayani, Janki, Bhojwani, Deepika, Bhuiyan, Salimuzzaman, Bibby, Anna, Bibi, Fatima, Bibi, Naheeda, Bibi, Salma, Bicanic, Tihana, Bidgood, Sarah, Bigg, Julie, Biggs, Sarah, Biju, Alphonsa, Bikov, Andras, Billingham, Sophie, Billings, Jessica, Binns, Alice, BinRofaie, Muhammad, Bintcliffe, Oliver, Birch, Catherine, Birch, Jenny, Birchall, Katherine, Bird, Sam, Bird, Sumedha, Birt, Mark, Bishop, Kilanalei, Bishop, Linda, Bishop, Lisa, Bisnauthsing, Karen, Biswas, Nibedan, Biuk, Sahar, Blachford, Karen, Black, Ethel, Black, Helen, Black, Karen, Black, Mairead, Black, Polly, Blackgrove, Hayley, Blackledge, Bethan, Blackler, Joanne, Blackley, Samantha, Blackman, Helen, Blackstock, Caroline, Blakemore, Francesca, Blamey, Helen, Bland, Alison, Blane, Sujata, Blankley, Simon, Blaxill, Parry, Blaylock, Katie, Blazeby, Jane, Blencowe, Natalie, Bloom, Ben, Bloomfield, Jack, Bloss, Angela, Bloxham, Hannah, Blundell, Louise, Blunsum, Andrew, Blunt, Mark, Blyth, Ian, Blyth, Kevin, Blythe, Andrew, Blythe, Karen, Boampoaa, Marilyn, Bobie, Boniface, Bobruk, Karen, Bodalia, Pritesh, Bodasing, Neena, Bodenham, Tanya, Boehmer, Gabriele, Boffito, Marta, Bohmova, Kristyna, Bokhandi, Sumit, Bokhar, Maria, Bokhari, Saba, Bokhari, Sakina, Bokhari, Syed O, Boles, Ambrose, Bond, Charlotte, Bond, Helena, Bond, Stuart, Bond, Thomas, Bone, Alice, Boniface, Georgia, Bonney, Lizzy, Borbone, Joanne, Borman, Naomi, Bottrill, Fiona, Bough, Laura, Boughton, Hayley, Boult, Zoe, Bourke, Miriam, Bourke, Stephen, Bourne, Michelle, Bousfield, Rachel, Boustred, Lucy, Bowes, Alexandra, Bowes, Amy, Bowker, Philip, Bowman, Louise, Bowman, Simon, Bowmer, Rachel, Bowring, Angie, Bowyer, Helen, Boyd, Jenny, Boyd, Laura, Boyle, Namoi, Boyle, Pauline, Boyle, Rosalind, Boyles, Louise, Brace, Leanna, Bradder, Jodie, Bradley, Clare Jane, Bradley, Pamela, Bradley, Patrick, Bradley, Paul, Bradley-Potts, Joanne, Bradshaw, Lynne, Bradshaw, Zena, Brady, Rebecca, Brady, Shirin, Braganza, Denise, Branch, Marie, Brankin-Frisby, Thomas, Brannigan, Jamie, Brassington, Louise, Brattan, Sophie, Bray, Fiona, Bray, Nancy, Brazil, Manny, Brear, Lucy, Brear, Tracy, Brearey, Stephen, Bremner, Laura, Brend, Morwenna, Bretland, Giovanna, Brewer, Chris, Bridgwood, Gavin, Brigham, Sara, Bright, John, Brightling, Chris, Brimfield, Lutece, Brinkworth, Elaine, Brittain-Long, Robin, Britten, Vianne, Broad, Lauren, Broad, Sarah, Broadhurst, Rosie, Broadley, Andrew, Broadway, Marie, Brockelsby, Christopher, Brocken, Megan, Brockley, Tomos, Brodsky, Mary, Brogan, Fiona, Brohan, Liz, Brokke, Felicity, Brolly, Jacob, Bromley, David, Brooke-Ball, Hannah, Brooker, Verity, Brookes, Matthew, Brooking, Deirdre, Brooks, Alison, Brooks, Karen, Brooks, Nicole, Brooks, Philip, Brooks, Rachel, Brooks, Sophie, Broomhead, Natalie, Broughton, Chloe, Broughton, Nathaniel, Brouns, Matt, Brown, Alison, Brown, Ammani, Brown, Carly, Brown, Catrin, Brown, Ellen, Brown, Heather, Brown, Janet, Brown, Louise, Brown, Niall, Brown, Pauline, Brown, Richard, Brown, Robert, Brown, Steven, Brown, Thomas, Browne, Bria, Browne, Charlotte, Browne, Duncan, Browne, Mitchell, Brownlee, Stephen, Brraka, Alba, Bruce, David, Bruce, Johanna, Bruce, Michelle, Brudlo, Wojciech, Brunskill, Nigel, Brunton, Alan, Brunton, Margaret, Bryant, Meera, Buazon, April, Buch, Maya H, Buchan, Ruaridh, Buchanan, Ruaridh, Buche, Danielle, Buck, Amanda, Buckland, Matthew, Buckley, Laura, Buckley, Philip, Buckley, Sarah, Buckman, Carol, Bugg, George, Bujazia, Ramadan, Bukhari, Marwan, Bukhari, Shanze, Bulbulia, Richard, Bull, Alex, Bull, Damian, Bull, Rhian, Bull, Thomas, Bulteel, Naomi, Bumunarachchi, Kasun, Bungue-Tuble, Roneleeh, Burchett, Caroline, Burda, Dorota, Burden, Christy, Burden, Thomas G, Burgess, Mika, Burgess, Richard, Burgess, Sophia, Burman, Adrian, Burnard, Sara, Burnett, Caroline, Burns, Amy, Burns, Collette, Burns, James, Burns, Karen, Burrage, Daniel, Burrows, Kate, Burston, Claire, Burton, Ben, Burton, Fiona, Burton, Matthew, Butcher, Deborah, Butler, Aaron, Butler, Jessica, Butler, Joanne, Butler, Joshua, Butler, Peter, Butler, Susan, Butt, Al-Tahoor, Butt, Mohammad M, Butterworth, Caryl, Butterworth-Cowin, Nicola, Buttery, Robert, Buttle, Tom, Button, Heather, Buttress, Daniel, Byrne, Jane, Byrne, Wendy, Byrne-Watts, Victoria, Cabandugama, Amanda, Cade, Ruth, Cadwgan, Anthony, Cahyareny, Ajeng, Cairney, Donna, Calderwood, James, Caldow, Darren, Calisti, Giorgio, Callaghan, Debbie, Callaghan, Jennifer, Callens, Claire, Callum, Donaldson, Calver, Caroline, Cambell-Kelly, Melissa, Camburn, Tracey, Cameron, David Richard, Cameron, Eleanor, Cameron, Fraser, Cameron, Sheena, Camm, Christian, Cammack, Renee F D, Campbell, Alison, Campbell, Amy, Campbell, Barbara, Campbell, Bridget, Campbell, Debbie, Campbell, Helen, Campbell, Hilary, Campbell, Jonathan, Campbell, Mark, Campbell, Robyn, Campbell, Wynny, Campbell Hewson, Quentin, Camsooksai, Julie, Canclini, Lisa, Candido, Shaula Mae, Candlish, Janie, Caneja, Cielito, Cann, Johnathon, Cannan, Ruby, Cannon, Emma, Cannon, Michael, Cannon, Petra, Cannons, Vivienne, Cantliff, Jane, Caplin, Ben, Capocci, Santino, Caponi, Noemi, Capp, Angelika, Capstick, Thomas, Cardwell, Mary, Carey, Rachel, Carley, Simon, Carlin, Tammy, Carmichael, Samantha, Carnahan, Mandy, Caroline, Charlotte, Carpenter, Jodi, Carr, Sharon, Carrasco, Anna, Carrington, Zoe, Carroll, Paul, Carter, Jonathan, Carter, Michael, Carter, Paul, Carter, Penny, Cartwright, Douglas, Cartwright, Jo-Anne, Carty, Claire, Carungcong, Jaime, Casey, Susan, Cassells, Annie, Cassimon, Barbara, Castiello, Teresa, Castle, Gail, Castles, Bridget, Caswell, Melanie, Catana, Ana Maria, Cate, Heidi, Cathcart, Susanne, Cathie, Katrina, Catley, Christine, Catlow, Laura, Caudwell, Matthew, Cavazza, Anna, Cave, Luke, Cavinato, Simon, Cawa, Frianne, Cawley, Kathryn, Caws, Chloe, Cendl, Hankins, Century, Hannah, Cernova, Jeva, Cesay, Mansur, Cetti, Ed, Chabane, Stephanie, Chablani, Manish, Chabo, Cathleen, Chadwick, David, Chadwick, Julie, Chadwick, Robert, Chakkarapani, Ela, Chakraborty, Arup, Chakraborty, Mallinath, Chakravorty, Mollika, Chalise, Bimal, Chalmers, James, Chalmers, Richard, Chamberlain, Georgina, Chamberlain, Sarah, Chambers, Emma, Chambers, Jonathan, Chambers, Lucy, Chambers, Naomi, Chan, Alex, Chan, Carmen, Chan, Cheuk, Chan, Evelyn, Chan, Kayen, Chan, Kimberley, Chan, Ping, Chan, Rebekah (Pui-Ching), Chan, Xin Hui, Chandler, Chris, Chandler, Heidi, Chandler, Kim Jessica, Chandler, Stuart, Chandler, Zoe, Chandra, Sumit, Chandran, Navin, Chandrasekaran, Badrinathan, Chang, Yvonne, Chaplin, Josephine, Chapman, Graeme, Chapman, John, Chapman, Katie, Chapman, Laura, Chapman, Lianne, Chapman, Polly, Chapman, Timothy, Chappell, Lucy C, Charalambou, Amanda, Charles, Bethan, Charlton, Dianne, Chatar, Kevin, Chatha, Calvin, Chaube, Ritesh, Chaudhary, Muhammad Yafaa Naveed, Chaudhry, Iram, Chaudhuri, Nazia, Chaudhury, Muhammad, Chauhan, Anoop, Chauhan, Ruchi Singh, Chavasse, Nicola, Chawla, Vipal, Cheater, Lindsay, Cheaveau, James, Cheeld, Charlotte, Cheeseman, Michelle, Chen, Fang, Chen, Hui Min, Chen, Terence, Cheng, Lok Yin, Cheng, Zhihang, Chenoweth, Helen, Cheong, Chun How, Cherian, Shiney, Cherrie, Mary, Cheshire, Helen, Cheung, Chee Kay, Cheung, Elaine, Cheung, Michelle, Chew, Victor, Cheyne, Claire, Chhabra, Swati, Chia, Wei Ling, Chiang, Eric, Chiapparino, Angela, Chicano, Rosavic, Chikwanha, Zviedzo Agenia, Chilcott, Sam, Chimbo, Phillipa, Chin, KokWai, Chin, Wen Jie, Chineka, Rumbidzai, Chingale, Amol, Chisem, Heather, Chisenga, Claire, Chisnall, Ben, Chiswick, Carolyn, Chita, Sunder, Chitalia, Nihil, Chiu, Matthew, Chivima, Brenda, Chmiel, Catherine, Choi, Soha, Choon Kon Yune, Willy, Choudhary, Vandana, Choudhury, Sarah, Chow, Bing-Lun, Chowdhury, Mahibbur, Chowdhury, Shahid, Christenssen, Victoria, Christian, Peter, Christides, Alexander, Christie, Fiona, Christmas, Daniel, Christopherson, Thereza, Christy, Mark, Chrysostomou, Paris, Chua, Yunli, Chudgar, Dip, Chudleigh, Richard, Chukkambotla, Srikanth, Chukwu, Michael Eze, Chukwulobelu, Izu, Chung, Chi Y, Church, Elaine, Church, Sara R, Churchill, David, Cianci, Nicole, Cicconi, Paola, Cinardo, Paola, Cipinova, Zdenka, Cipriano, Bessie, Clamp, Sarah, Clapham, Melanie, Clare, Edel, Clare, Sarbjit, Clark, Andrew, Clark, Charlotte, Clark, Diane, Clark, Felicity, Clark, Gabrielle, Clark, James, Clark, Katherine, Clark, Kaylea, Clark, Louise, Clark, Lucy, Clark, Matthew, Clark, Patricia, Clark, Richard, Clark, Thomas, Clark, Zoe, Clarke, Andrea, Clarke, Paul, Clarke, Robert, Clarke, Roseanne, Clarke, Samantha, Clarke, Sheron, Claxton, Alleyna, Clay, Kate, Clayton, Elizabeth, Clayton, Olivia, Clayton-Smith, Jill, Cleaver, Chris, Clemente de la Torre, Carlota, Clements, Jayne, Clements, Suzanne, Clifford, Rachael, Clifford, Sarah, Clive, Amelia, Clouston, Jonathan, Clueit, Samantha, Clyne, Andrea, Coakley, Michelle, Coakley, Peter Gerald Leyland, Cobain, Kathryn, Cochrane, Alexandra, Cochrane, Patricia, Cockerell, Maeve, Cockerill, Helen, Cocks, Shirley, Codling, Rachel, Coe, Adam, Coetzee, Samantha, Coey, David, Cohen, Danielle, Cohen, Jonathan, Cohen, Oliver, Cohn, Mike, Coke, Louise, Coker, Olutoyin, Colbeck, Nicholas, Colbert, Roghan, Cole, Esther, Cole, Jade, Cole, Joby, Coleman, Garry, Coleman, Matt, Coles, Holly, Colin, Macleod, Colino-Acevedo, Alicia, Colley, Julie, Collier, Dawn, Collier, Heather, Collini, Paul, Collins, Emma, Collins, Jaimie, Collins, Joanne, Collins, Nicola, Collins, Sally, Collins, Vicky, Collinson, Andrew, Collinson, Bernadette, Collinson, Jennifer, Collis, Matthew, Colmar, Madeleine, Colton, Hayley Emma, Colton, James, Colville, Katie, Colvin, Carolyn, Combes, Edward, Comer, David, Comerford, Alison, Concannon, Dónal, Condliffe, Robin, Connell, Lynne, Connell, Natalie, Connelly, Karen, Connolly, Gavin, Connor, Emma, Conroy, Antonia, Conteh, Veronica, Convery, Rory, Conway, Francesca, Conway, Grainne, Conway, Rhiannon, Conyngham, Jo-Anna, Cook, Colette, Cook, Eloise, Cook, Gemma, Cook, Helen, Cook, Julie, Cooke, Danielle, Cooke, Graham, Cooke, Katrina, Cooke, Tim, Cooper, Adele, Cooper, Chris, Cooper, David, Cooper, Helen, Cooper, Jamie, Cooper, Lauren, Cooper, Nick, Cooper, Rowena, Cope, Thomas, Corbet, Sinead, Corbett, Carolyn, Corcoran, John, Cordell, Chris, Cordle, Jessica, Corfield, Alasdair, Corless, John, Corlett, Alison, Cornwell, Joe, Cornwell, Michael, Corogeanu, Diana, Corredera, Mirella, Corrigan, Ruth, Corser, Rita, Cosgrove, Denise, Cosier, Tracey, Costa, Patricia, Coston, Charlie, Cotgrove, Susannah, Coton, Zoe, Cottam, Lisa-Jayne, Cotter, Rhiannon, Cotterill, Donna, Cotton, Caroline, Coull, Andrew, Coulson, James, Counsell, David, Counter, David, Coupland, Cherry, Courtney, Ellie, Courtney, Julia, Cousins, Rebecca, Cowan, Alexander, Cowan, Elena, Cowell, Richard, Cowen, Louise, Cowman, Steve, Cowton, Amanda, Cox, Ellie, Cox, Giles, Cox, Karina, Cox, Miriam, Coy, Karen, Cradduck-Bamford, Andrea, Craig, Victoria, Craighead, Felicity, Cramp, Matthew, Crause, Jacolene, Crawford, Angie, Crawford, Emma, Crawford, Isobel, Crawshaw, Sarah, Creagh-Brown, Ben, Creamer, Andrew, Cremona, Joanne, Cremona, Saveria, Cresswell, Janet, Cribb, Mark, Crichton, Charles, Crilly, Declan, Crisp, Lauren, Crisp, Nikki, Crocombe, Dominic, Croft, Maria, Crooks, Jennifer, Crosby, Harriet, Cross, Elizabeth, Cross, Tim, Crothers, Amy, Crotty, Stephen, Crouch, Susan, Crow, Madeleine, Crowder, Amanda, Crowley, Kate, Crowley, Teresa, Croysdill, Rebecca, Cruickshank, Callum, Cruickshank, Conor, Cruickshank, Irena, Cruise, James, Cruz, Carina, Cruz Cervera, Trino, Cryans, Dominic, Cui, Guanguo, Cui, Helen, Cullen, Lorraine, Cummings-Fosong, Gillian, Cunliffe, Victoria, Cunningham, Neil, Cunningham, Nicola, Cupitt, Jason, Curgenven, Hollie, Curnow, Gerens, Curran, David, Curran, Simon, Currie, Craig, Currie, Jacqueline, Currie, Scarlett, Curtis, Jonathan, Curtis, Katrina, Curtis, Olivia, Curtis, Thomas, Cuthbertson, Rebecca, Cutler, Sean, Czekaj, Marta, Czylok, Patrycja, da Rocha, Joana, Dagens, Andrew, Daggett, Helen, Daglish, Jacqui, Dahiya, Sandeep, Dale, Anne, Dale, Katie, Dale, Michaela, Dale, Sam, Dales, Jolyon, Dalgleish, Helen, Dallow, Helen, Dalton, Dermot, Daly, Zoe, Danga, Akila, Daniel, Amelia, Daniel, Priya, Daniels, Allison, Dann, Adela, Danso-Bamfo, Sandra, Darbyshire, Alex, Darbyshire, Janet, Dargan, Paul, Dark, Paul, Darlington, Kate, Darton, Tom, Darylile, Guledew, Das, Manjusha, Das, Sukamal, Daschel, Martin, Dasgin, Joanne, Datta, Dibyendu, Daunt, Anna, Davenport, Emily, Davey, Mark, Davey, Miriam, Davey, Molly, David, Mini, Davidson, Alexander, Davidson, Laura, Davidson, Neil Davidson, Davidson, Richard, Davies, Albert, Davies, Amanda, Davies, Amy, Davies, Angela, Davies, Carolyn, Davies, Catrin, Davies, Drew, Davies, Elaine, Davies, Ffyon, Davies, Helen, Davies, Jim, Davies, Karen, Davies, Kelly, Davies, Kim, Davies, Louisa, Davies, Matthew, Davies, Michelle, Davies, Nina, Davies, Owen, Davies, Patrick, Davies, Rachel, Davies, Rhys, Davies, Ruth, Davies, Sarah, Davies, Simon, Davis, Gwyneth, Davis, Illinos, Davis, Julie-Ann, Davis, Katherine, Davis, Peter, Davison, Alexander, Dawe, Christine, Dawe, H, Dawkins, Mark, Dawson, Danielle, Dawson, Elizabeth, Dawson, Joy, Dawson, Susan, Dawson, Tom, Daxter, Andrew, Day, Andrew, Day, Jacob, Day, Jeremy N, D'Costa, Jamie, De, Parijat, de Fonseka, Duneesha, de Freitas, Toni, De Santana Miranda, Frederico, de Sausmarez, Eleanor, de Silva, Shanika, de Silva, Thushan, De Sousa, Jessica, De Sousa, Paulo, de Souza, James, de Soyza, Anthony, de Vere, Natasha, de Vos, Johannes, Deacon, Bethan, Dealing, Sharon, Dean, Anna, Dean, Julie, Dean, Katrina, Dean, Stephen, Dean, Tessa, Deane, Jill, Dear, James, Dearden, Effie, Deas, Catherine, Debbie, Samuel, Debreceni, Gabor, Deelchand, Vashist, Deeley, Matthew, Deery, Joanne, Defever, Emmanuel, Del Forno, Manuela, Dela Rosa, Arnold, Dell, Amanda, Demetriou, Carrie, DeMets, David, Democratis, Jane, Denham, Jacqueline, Denis, Emmanuelle, Denley, Laura, Denmade, Craig, Dent, Kathy, Dent, Martin, Denton, Elise, Denwood, Tom, Deole, Nishigandh, Depala, Darshita, Depante, Maria, Dermody, Susan, Desai, Amisha, Desai, Asmita, Desai, Purav, Deshpande, Sanjeev, Deshpande, Vai, Devkota, Sirjana, Devkota, Usha, Dey, Prakash, Dey, Vishal, Deylami, Rogin, Dhaliwal, Kevin, Dhani, Sundip, Dhanoa, Amandeep, Dhar, Mili, Dhasmana, Devesh, Dhillon, Ekanjali, Dhillon, Reiss, Dhimal, Meghnath, Dias, Priya, Diaz, Stephanie, Diaz-Pratt, Kayleigh, Dickerson, Debbie, Dicks, Pamela, Dickson, Stuart, Dillane, Sean, Diment, Sarah, Dimitri, Paul, Dinh, Thai Ha, Dipper, Alex, Dirmantaite, Laura, Ditchfield, Lisa, Diver, Sarah, Diwakar, Lavanya, Dixon, Caroline, Dixon, Giles, Djeugam, Brice, Dlouhy, Petr, Dmitri, Paul, Dobbie, Laurence, Dobranszky Oroian, Marinela, Dobson, Charlotte, Dobson, Lee, Docherty, Marie, Dockrell, David, Dodd, James, Dodds, Jackie, Dodds, Rebecca, Dodds, Steve, Dogra, Richi, Doherty, Erin, Doherty, Warren, Doi, Yumiko, Doig, Iain, Doke, Eleanor, Dolan, Daniel, Dolman, Mark, Dolman, Rozzie, Donald, Lisa, Donaldson, Callum, Donaldson, Christopher, Donaldson, Denise, Donaldson, Gillian, Donaldson, Kate, Donnachie, Joanne, Donnelly, Christopher, Donnelly, Eilish, Donnelly, Ronan, Donohoe, Aravindhan, Donohoe, Gemma, Donohue, Bryan, Donton, Sinead, Dooks, Emma, Doran, Grainne, Dorey, Kane, Dorgan, Sharon, Dosani, Moonira, Dosanjh, Davinder, Dospinescu, Paula, Douglas, Katie, Douse, Jonathan, Dowden, Lucy, Dower, Michelle, Dowling, Sud, Downer, Nicola, Downes, Charlotte, Downes, Rob, Downes, Thomas, Downey, Damian, Downey, Robert, Downs, Louise, Dowson, Simon, Dragan, Cornel, Dragos, Cristina, Drain, Maire, Drake, Chelsea, Drew, Victoria, Drewett, Olivia, Driscoll, Celine, Drogan, Helena, Drummond, Graham, Druyeh, Ronald, Dryburgh-Jones, Jack, Drysdale, Simon, Du Thinh, An, Dube, Hazel, Dube, Judith, Duberley, Stephen, Duckles-Leech, Hayley, Duff, Nicola, Duffield, Emma, Duffy, Helen, Dufour, Lionel, Duggan, Annette, Dugh, Parveen, Duignan, Janice, Dummer, Simon, Duncan, Andrew, Duncan, Christopher, Duncan, Fullerton, Duncan, Gregory, Dundas, Stephanie, Dunn, Alessia, Dunn, Charlotte, Dunn, Damian, Dunn, Laura, Dunn, Paul, Dunne, Charlene, Dunne, Karen, Dunning, Fiona, Dunphy, Aidan, Duraiswamy, Venkat, Duran, Beatriz, DuRand, Ingrid, Duric, Natalie, Durie, Alison, Durie, Emily, Durrington, Hannah, Duvnjak, Haris, Dwarakanath, Akshay, Dwarakanath, Laasya, Dwyer, Ellen, Dyball, Claudia, Dyer, Kristyn, Dymond, Harvey, Dymond, Tom, Eades, Chris, Eagles, Laura, Early, Joanne, Earwaker, Melissa, Easom, Nicholas, East, Clare, Easthope, Amy, Easton, Fraser, Eatough, Ruth, Ebert, Beate, Ebigbola, Oluwadamilola, Ebon, Martin, Eccles, Sinan, Eddings, Chloe, Eddleston, Michael, Edgar, Maureen, Edgerley, Katharine, Edmond, Nicholas, Edmondson, Mary, Edmunds, Tracy, Edwards, Alexandra, Edwards, Catherine, Edwards, Joy, Edwards, Kennedy, Edwards, Mandy, Eedle, Jenny, Egginton, Dawn, Ehiorobo, Loveth, Eisen, Sarah, Ekeowa, Ugochukwu, Ekoi, Mohamed, Ekunola, Ayomide, El Behery, Soha, Elbeshy, Mohamed, El-Bouzidi, Kate, Elder, Jennifer, El-Din, Mohammed, Eleanor, Diana, Eletu, Ibrahim, Elfar, Eman, Elgamal, Mayy Magdy, Elgohary, Amr, Elia, Stellios, Elias, Jennifer, Elias, Tania, Elkaram, Nadia, Elkins, Andrew Victor, Ellam, Julie, Ellard, Nikki, Ellerton, Laura Nicola, Elliot, Lucy, Elliott, Amy, Elliott, Fiona, Elliott, Kerry, Elliott, Scott, Ellis, Annie, Ellis, Christine, Ellis, Kaytie, Ellis, Tak-Yan, Ellis, Yvette, Elmahdi, Rahma, Elmahi, Einas, Elmasry, Hannah-May, Elndari, Najla, Elneima, Omer, Elokl, Mohamed, Elradi, Ahmed, Elsaadany, Mohamed, El-Sayeh, Sally, El-Sbahi, Hana, Elsefi, Tarek, El-Shakankery, Karim, El-Taweel, Hosni, Elyoussfi, Sarah, Emberey, Jonathan, Emberson, Jonathan R, Emberton, John, Emmanuel, Julian, Emmerson, Ingrid, Emms, Michael, Emond, Florence, Emonts, Marieke, Enachi, Nicu, Engden, Angila, English, Katy, Entwistle, Emma, Enyi, Hene, Erotocritou, Marios, Eskander, Peter, Esmail, Hanif, Evans, Brynach, Evans, Chris, Evans, Debra, Evans, Gail, Evans, Gareth, Evans, Jennifer, Evans, Jolanta, Evans, Lisa, Evans, Lynn, Evans, Mim, Evans, Morgan, Evans, Ranoromanana, Evans, Teriann, Evans, Terry J, Everden, Caroline, Everden, Serenydd, Evison, Hayley, Evison, Lynsey, Faccenda, Jacqueline, Fahel, Leila, Fahmay, Youstina, Fairbairn, Sara, Fairbairn, Terry, Fairclough, Andy, Fairlie, Louise, Fairweather, Mark, Fajardo, Anne, Falcone, Naomi, Falconer, Euan, Fallon, John, Fallow, Andrea, Faluyi, David, Fancois, Victoria, Farah, Qayyum, Fard, Novin, Fares, Leila, Farg, Amr, Farmer, Adam, Farmer, Katie, Farmery, Toni, Farnworth, Samantha, Farook, Faiyaz, Farooq, Hadia, Farooq, Sidrah, Farquhar, Fiona, Farrell, Aaron, Farrell, Barbara, Farthing, James, Farzana, Syeda, Fasina, Rahmatu, Fatemi, Azam, Fatemi, Mina, Fatimah, Nibah, Faulkner, Maria, Faust, Saul N, Fawke, Joe, Fawohunre, Sinmidele, Fazal, Abul, Fearby, Simon, Feben, Alex, Fedel, Federico, Fedorova, Daria, Fegan, Christopher, Felongco, Mae, Felton, Lynsey, Felton, Tim, Fenlon, Kate, Fenn, Andrea, Fenner, Isabelle, Fenton, Ciara, Fenton, Melisa, Ferguson, Cameron, Ferguson, Jenny, Ferguson, Kathryn, Ferguson, Katie, Ferguson, Susan, Ferguson, Susie, Ferguson, Victoria, Fernandes, Denzil, Fernandez, Candida, Fernandez, Eduardo, Fernandez, Maria, Fernandez Lopez, Sonia, Fernando, Callum Jeevan, Feroz, Ahmed, Ferranti, Pietro, Ferrari, Thais, Ferrelly, Eleanor, Ferrera, Alexandra, Ferriman, Emma, Fethers, Nicholas, Field, Ben, Field, Janet, Field, Rebecca, Fielder, Karen, Fieldhouse, Lindsey, Fielding, Andra, Fielding, Julie, Fielding, Sarah, Fikree, Asma, Filson, Sarah Ann, Finbow, Sarah, Finch, Debbie, Finch, Joanne, Finch, Laurie, Fineman, Natalie, Finlayson, Lauren, Finn, Adam, Finn, Joanne, Finney, Clare, Fiouni, Sofia, Fiquet, Jo, Fisher, James, Fisher, Neil, Fishman, Daniel, Fishwick, Krystofer, Fitzgerald, Fiona, Flaherty, Jan, Flanagan, Michael, Flanders, Charles, Fleming, Julie, Fleming, Lucy, Fleming, Paul, Flesher, William, Fletcher, Alison, Fletcher, Jonathan, Fletcher, Lucy, Fletcher, Simon, Fletcher, Sophie, Flewitt, Karen, Flood, Christopher, Floodgate, Ian, Florence, Vincent, Floyd, Sharon, Flynn, Rachel, Foden, Claire, Fofana, Adama, Fogarty, Georgina, Foley, Paul, Folkes, Linda, Font, Daniela Mock, Foo, Aiwyne, Foo, Jane, Foot, Andrew, Foot, Jayne, Forbes, Jane, Ford, Jamie, Foreman, Jennifer, Fornolles, Caroline, Forrest, Adam, Forsey, Ellie, Forsey, Miranda, Forshall, Thomas, Forster, Elliot, Forton, Julian, Foster, Emily, Foster, Joseph, Foster, Rachel Anne, Foster, Tracy, Foulds, Angela, Foulds, Ian, Fowe, Folakemi, Fowler, Emily, Fowler, Robert, Fowler, Stephen, Fox, Claire, Fox, Heather, Fox, Jonathan, Fox, Lauren, Fox, Natalie, Fox, Olivia, Fox, Simon, Foxton, Sarah-Jane, Frake, Rebecca, Francioni, Alex, Francis, Olesya, Francis, Rebecca, Francis, Sarah, Francis-Bacon, Theodora, Frankland, Helen, Franklin, Jessica, Fraser, Catherine, Frayling, Sharon, Fredlund, Martyn, Freeman, Carol, Freeman, Elaine, Freeman, Hannah, Freeman, Nicola, Freer, Clare, French, Eleanor, Frise, Matthew, Fromson, Renate, Froneman, Claire, Frosh, Adam, Frost, John, Frost, Victoria, Froud, Oliver, Frowd, Rachel, Fryatt, Arun, Fuller, Bridget, Fuller, Liz, Fuller, Tracy, Fullerton, Duncan, Fung, Carrie, Fung, Gayle, Funnell, Sarah, Furness, John, Fyfe, Andrew, G, Nytianandan, Gabbitas, Elizabeth, Gabriel, Claire, Gabriel, Zoë, Gachi, Hadiza, Gahir, Joshua, Gajebasia, Sarveen, Gajewska-Knapik, Katarzyna, Gale, Christopher, Gale, Hugo, Gale, Rebecca, Gali, Swetha, Gallagher, Bernadette, Gallagher, Jude, Gallagher, Rosie, Gallagher, William, Galliford, Joanne, Galloway, Catherine, Galloway, Chris, Galloway, Emma, Galloway, Jacqui, Galloway, James, Gamble, Laura, Gamble, Liz, Gammon, Brian, Ganapathi, Jaikumar, Ganapathy, Ramesh, Gandhi, Kaminiben, Gandhi, Sarah, Ganesh, Usha, Gani, Abrar, Garden, Emma-James, Gardener, Antoni Dariusz, Gardiner, Emma, Gardiner, Michael, Gardiner, Phil, Gardiner, Siobhan, Gardiner-Hill, Caroline, Gardner, Jonathan, Garfield, Mark, Garg, Atul, Garlick, Nathan, Garner, Justin, Garner, Lucie, Garner, Zoe, Garr, Rosaline, Garty, Florence, Gascoyne, Rachel, Gashau, Hyeriju, Gatenby, Aoife, Gaughan, Erin, Gaurav, Alok, Gavrila, Mariana, Gaylard, Jane, Gaywood, Emma, Geddie, Catherine, Gedge, Ian, Gee, Sarah, Gellamucho, Minerva, Gelly, Karzan, Gelmon, L, Gelmon, Leila, Gelves-Zapata, Sandra, Genato, Gemma, Gent, Susan, Geoghegan, Natalie, George, Sam, George, Tina, Georges, Simon, Georgiou, Domonique, Gerard, Peter, Gerdes, Leigh, Germain, Louise, Gerrish, Helen, Getachew, Abel, Gethin, Louise, Ghanayem, Hisham, Gherman, Anca, Ghosh, Alison, Ghosh, Justin, Ghosh, Sudhamay, Giannopoulou, Sarra, Gibani, Malick, Gibbison, Ben, Gibbons, Kerry, Gibson, Alex, Gibson, Bethan, Gibson, Kimberley, Gibson, Kirsty, Gibson, Sian, Gilbert, Cat, Gilbert, Jeanette, Gilbert, Kayleigh, Giles, Benjamin, Gill, Mandy, Gill, Lynne, Gillen, Paul, Gillesen, Annelies, Gillespie, Katherine, Gillham, Elizabeth, Gillian, Andrew, Gilliland, Deborah, Gillott, Robert, Gilmour, Danielle, Gilmour, Kate, Ginting, Franciscus, Giokanini-Royal, Theodora, Gipson, Anna, Girling, Joanna, Gisby, Rhian, Gkioni, Angelena, Gkoritsa, Aikaterini, Gkrania-Klotsas, Effrossyni, Gladwell, Amy, Glanville, James, Glasgow, Jessica, Glasgow, Susannah, Glass, Jon, Glass, Lynn, Glaysher, Sharon, Gledhill, Lisa, Glennon, Ana, Glover, John, Glover, Kyle, Glover Bengtsson, Jan, Gnanalingam, Chevanthy, Goddard, Julie, Goddard, Wendy, Godden, Emily, Godden, Jo, Godson, Emma, Gogoi, Sukanya, Goh, Aiky, Goiriz, Rebeca, Gokaraju, Sriya, Goldacre, Raphael, Goldsmith, Arthur, Goldsmith, Portia, Gomersall, Darren, Gomez, Lucia, Gomez-Marcos, Raquel, Gondal, Ali, Gonzalez, Celia, Goodall, Jack, Goodenough, Bob, Goodfellow, Laura, Goodlife, James, Goodwin, Camelia, Goodwin, Elizabeth, Goodwin, Jayne, Goodyear, Paula, Gooentilleke, Rajiv, Goonasekara, Michelle, Gooseman, Sheila, Gopal, Shameer, Gordon, Sally, Gorick, Hugh, Gorman, Caitlin, Gorman, Claire, Gormely, Stuart, Gorog, Diana, Gorst, Michelle, Gorsuch, Thomas, Gosai, Jayshreebahen, Gosling, Rebecca, Gosling, Sally, Gosney, Georgina, Goss, Vanessa, Gotham, Dzintars, Gott, Naomi, Goudie, Elizabeth, Gould, Susan, Gourbault, Lysander, Govind, Abha, Gowans, Sharon, Gowda, Girish, Gowda, Rohit, Gower, Hannah, Gower, Thomas, Goyal, Pankaj, Goyal, Sunil, Goyal, Sushant, Graham, Clive, Graham, Jonathan, Graham, Justin, Graham, Libby, Graham, Sharon, Graham-Brown, Matthew, Grahamslaw, Julia, Grana, Gianluca, Grandison, Tracyanne, Grandjean, Louis, Grant, Alison, Grant, Ann, Grant, David, Grant, Matthew, Grant, Pauleen, Gravell, Rhys, Graves, Jenny, Gray, Alasdair, Gray, Catherine, Gray, Georgina, Gray, Jackie, Gray, Karen, Gray, Nicola, Gray, Sebastian, Grayson, Alan, Greaves, Fiona, Greaves, Paul, Green, Alastair, Green, Charlotte, Green, Christopher A, Green, David, Green, Frederick, Green, Joel, Green, Marie, Green, Nicola, Green, Stacey, Greene, Diarra, Greenfield, Philippa, Greenhalgh, Alan, Greenwood, Daniel, Greer, Sandra, Gregory, James, Gregory, Jane, Gregory, Katie, Gregory, Tamsin, Greig, Jill, Greig, Julia, Grenfell, Rebecca, Grenier, Teena, Grevatt, Susan, Grey, Glaxy, Gribbin, Andrew, Gribble, Amy, Grieg, Natasha, Grieve, Douglas, Griffin, Ben, Griffin, Denise, Griffin, Mel, Griffith, Sian, Griffiths, Andrew, Griffiths, Daniel, Griffiths, David, Griffiths, Donna, Griffiths, Isabel, Griffiths, Mark, Griffiths, Nicola, Griffiths, Oliver, Griffiths, Sarah, Griffiths, Yvonne, Grigoriadou, Sofia, Grigsby, Steph, Grobovaite, Evelina, Grondin, Clarissa, Groome, Rachel, Grosu, Liliana, Grounds, Jenny, Grout, Margaret, Grover, Helen, Groves, Jayne, Grubb, Neil, Grundy, Julie, Guarino, Francesca, Gudur, Sharada, Guettari, Sharazeq, Gulati, Shivang, Gulia, Vikas, Gunasekera, Pumali, Gunawardena, Malin, Gunganah, Kirun, Gunn, Jessica, Gunter, Emma, Gupta, Alok, Gupta, Atul, Gupta, Rajeev, Gupta, Richa, Gupta, Rishi, Gupta, Tarun, Gupta, Vineet, Gupta-Wright, Ankur, Guratsky, Victoria, Gureviciute, Alvyda, Gurram, Sambasivarao, Gurung, Anju, Gurung, Bhawana, Gurung, Shraddha, Guth, Hazel, Gyanwali, Pradip, Habibi, Ruth, Hack, Berkin, Hackney, Pamela, Hacon, Christian, Haddad, Aiman, Hadfield, Denise, Hadjiandreou, Michalis, Hadjisavvas, Nikolaos, Haestier, Anna, Hafiz, Nauman, Hafiz-Ur-Rehman, Rana, Hafsa, Javed, Hagan, Samantha, Hague, Jack William, Hague, Rosemary, Haigh, Kate, Haines, Christina, Hainey, Scott, Hair, Morton, Hairsine, Brigid, Hajnik, Juraj, Haldeos, Anne, Halder, Writaja, Hale, Jennie, Halevy, Carmel, Halford, Paul, Halford, William, Hall, Alistair, Hall, Anthony, Hall, Claire, Hall, Elizabeth, Hall, Fiona, Hall, Helen, Hall, Jennifer, Hall, Kathryn, Hallas, Jan, Hallas, Kyle, Hallett, Charles, Halls, Heather, Hamdollah-Zadeh, Maryam, Hameed, Bilal, Hamers, Raph, Hamers, Raph L, Hamid, Imran, Hamie, Mohamad, Hamilton, Bethany, Hamilton, Fergus, Hamilton, Leigh, Hamilton, Nicola, Hamlin, Ruth, Hamlyn, Eleanor, Hammans, Beatrice, Hammersley, Shirley, Hammerton, Kate, Hammond, Bev, Hammond, Leah, Hammonds, Fiona, Hamoodi, Ibrahim, Hampshire, Karen, Hampson, Jude, Hampson, Lucy, Hanci, Ozan, Hand, Sadiyah, Handford, Jasmine, Handrean, Soran, Haney, Sarah, Hanif, Sheharyar, Hanison, E, Hanison, Esther, Hannah, Jennifer, Hannington, Amy, Hannun, Merhej, Hanrath, Aidan, Hanson, Anita, Hanson, Jane, Hanson, Kathryn, Hanson, Steve, Haq, Mazhar Ul, Haqiqi, Ala, Haque, Monjurul, Harden, Lesley, Harding, Zoe, Hardman, Simon, Hardy, Joanna, Haresh, Kumar, Harford, Rachel, Hargadon, Beverley, Hargreaves, Carolyn, Hargreaves, James, Harin, Alice, Haris, Mohammed, Harlock, Edward, Harman, Paula, Harman, Tracy, Harmer, Mark, Haroon, Muhammad A, Harper, Charlie, Harper, Heather, Harper, Peter, Harper, Rosemary, Harrhy, Sarah, Harrington, Sian, Harrington-Davies, Yasmin, Harris, Jade, Harris, Jess, Harris, John, Harris, Laura, Harris, Marie-Clare, Harris, Nichola, Harris, Sophie, Harrison, David, Harrison, Laura, Harrison, Melanie, Harrison, Rowan, Harrison, Susie, Harrison, Thomas, Harrison, Wendy, Harrod, Elizabeth, Hart, Ciaran, Hart, Dominic, Hartley, Lisa, Hartley, Rosemary, Hartley, Ruth, Hartley, Tom, Hartrey, William, Hartridge, Phillipa, Hartshorn, Stuart, Harvey, Alice, Harvey, Angela, Harvey, Max, Harwood, Catherine, Harwood, Helen, Haselden, Brigitte, Hashem, Kazi, Hashimm, Mohammed, Hashimoto, Tadaaki, Hashmi, Imranullah, Haslam, Zena, Hassan, Adil, Hassan, Ali, Hassan, Wagae UI, Hassan, Waqar Ul, Hassasing, Sapna, Hassell, Jane, Hassell, Philip, Hastings, Alex, Hastings, Bethany, Hastings, Janice, Hatton, Jonathan, Havinden-Williams, May, Havlik, Stefan, Hawcutt, Daniel B, Hawes, Kadean, Hawes, Liz, Hawes, Nicola, Hawkins, Annie, Hawkins, Nancy, Hawley, Dan, Hawley-Jones, Ed, Haworth, Edward, Hay, Cathy, Hayat, Amna, Hayat, Jamal, Hayathu, Mohamed-Riyal, Hayes, Anne, Hayes, Jonas, Hayes, Kate, Hayes, Melony, Hayes, Fiona, Hayle, Patrick, Haylett, Chloe, Hayman, Antara, Hayman, Melanie, Haynes, Matthew, Haynes, Richard, Hayre, Rachel, Haysom, Sarah, Hayward, James, Haywood, Patrick, Hazelton, Tracy, Hazenberg, Phoebe, He, Zhengmai, Headon, Elizabeth, Heal, Carrie, Healy, Brendan, Hearn, Amy, Heath, Angela, Heath, Rowan, Heaton, Diane, Hebbron, Kerry, Hector, Gemma, Hedges, Andy, Hedges, Katrine, Heeley, Cheryl, Heeney, Elaine, Heire, Rajdeep, Hemmila, Ulla, Hemphill, Scott, Hemsley, Deborah, Henderson, Abigail, Henderson, Jennifer, Henderson, Steven, Henry, Joanne, Henry, Karol, Henry, Lavinia, Henry, Margo, Henry, Natalie, Henshall, David, Herdman, Gillian, Herdman-Grant, Rosaleen, Herkes, Morag, Heron, Emma, Herrington, William, Heselden, Emilia, Heslop, Peta, Hester, Simon, Hetherington, Emily, Hetherington, Joseph, Hettiarachchi, Chamila, Hettiarachchi, Pramodh, Hewer, Hayley, Hewertson, John, Hewetson, Anna, Hewins, Sue, Hewitt, Claire, Hewitt, Davina, Hewitt, Richard, Hey, Samuel, Heyderman, Robert, Heydtmann, Mathis, Heys, Joseph, Heywood, Jonathan, Hibbert, Meg, Hickey, John, Hickey, Naomi, Hickey, Peter, Hicks, Alex, Hicks, Jenny, Hicks, Scott Rory, Higbee, Daniel, Higgins, Lucy, Higham, Andrew, Highcock, Martin, Highgate, Judith, Hikmat, Mondy, Hill, Amanda, Hill, Helen, Hill, Joanne, Hill, Lisa, Hill, Phoebe, Hill, Uta, Hilldrith, Annette, Hillman-Cooper, Catherine, Hilton, Zoe, Hinch, Sarah, Hindle, Andrew, Hindmarsh, Alice, Hine, Paul, Hinshaw, Kim, Hird, Clare, Hives, Jemma, Ho, Benson, Hoare, Michaela, Hobden, David, Hobden, Gill, Hobrok, Maria, Hobson, Simon, Hodge, Simon, Hodgen, Lesley, Hodgkins, Holly, Hodgkinson, Louise, Hodgkinson, Sally, Hodgson, David, Hodgson, Helen, Hodgson, Luke, Hodgson, Sheila, Hodkinson, Gemma, Hodson, Kenneth, Hogben, Matthew, Hogg, Lucy, Hoggett, Lee, Holborow, Abigail, Holbrook, Catherine, Holden, Catherine, Holden, Melinda, Holder, Thomas, Holdhof, Niels, Holdsworth, Hannah, Holland, Lisa, Holland, Nicky, Hollands, Marie, Holliday, Elizabeth, Holling, Nina, Hollos, Laszlo, Holloway, Simon, Hollyer, Marcus, Holman, Amy, Holmes, Ann, Holmes, Megan, Holmes, Raphael, Holmes, Rebecca, Holroyd, Kelly, Holt, Lyndsey, Holt, Siobhan, Holt, Susie, Holyome, Alexandra, Home, Marie, Homewood, Renate, Hong, Kate, Hooper, Clare, Hope, Samantha, Hope, Susan, Hopkins, Bridget, Horby, Peter W, Horler, Stephanie, Hormis, Anil, Hornan, Daniel, Hornby, Nicola, Horne, Zoey, Horner, Rebecca, Horsford, Latoya, Horsford, Megan, Horsford, Mark, Horsham, Valana, Horsley, Alexander, Horsley, Ashley, Horsley, Elizabeth, Horton, Sarah, Hosea, Jane, Hoskins, Toby, Hossain, Muhammad Shamim, Hossain, Rashed, Hough, Maxine, Hough, Sarah, Houghton, Catherine, Houghton, Kathryn, Houlihan, Rebecca, Housely, Kay, Houston, Hamish, Hovvels, Roseanna, How, Lee, Howaniec, Laura, Howard, Laura, Howard, Linda, Howard, Lucy, Howard, Sarah, Howard, Stuart, Howard-Griffin, Richard, Howe, Serena, Howells, Mark, Howie, Lyn, Howlett, Kerry, Howlett, Sophie, Hrycaiczuk, Josh, Htoon, Naing Zaya, Htwe, Su, Hu, Ying, Huah, Chiang Ooi Huah, Huckle, Abby, Huda, Shahzya, Hudak, Alison, Hudig, Lisa, Hudson, Heather, Hudson, Oli, Hufton, Alison, Huggins, Connor, Hughes, Alistair, Hughes, Emma, Hughes, Gareth, Hughes, Heather, Hughes, Luke, Hughes, Rachel, Hughes, Rebecca, Hughes, Samantha, Hughes, Stephen, Hughes, Vikki, Hughes, Wesley, Huhn, Lukas, Hui, Ching, Hulbert, Ruth, Hull, Diana, Hull, Grace, Hull, Robert, Hulme, Amanda, Hulme, Peter, Hulse, Wendy, Hulston, George, Hum, Ryan, Hume, Megan, Humphrey, Charlotte, Humphries, Alasdair, Humphries, Joanne, Hunt, Fiona, Hunt, Jonquil, Hunt, Kristen, Hunt, Luke, Hunt, Sophie, Hunter, Alexandra, Hunter, Karl, Hunter, Neil, Huntington, George, Hurditch, Elizabeth, Hurley, Cian, Hurley, Katrina, Husain, Mohammed A, Husaini, Syeda Y, Huson, Coralie, Hussain, Afreen, Hussain, Ibraar, Hussain, Ifza, Hussain, Mohammad, Hussain, Muhammad, Hussain, Reda, Hussain, Samia, Hussain, Sanniah, Hussain, Yasmin, Hussam El-Din, Mohammed, Hussey, Rebecca, Hutchinson, Anja, Hutchinson, Camille, Hutchinson, Dorothy, Hutchinson, Elizabeth, Hutchinson, John, Hutsby, Claire, Hutton, Paula, Huyen, Thuong, Hydes, Daniella, Hyde-Wyatt, Jamie, Hynes, Niamh, Hyslop, Megan, Ibraheim, Mazen, Ibrahim, Abdalla, Ibrahim, Ahmed, Ibrahim, Asil, Ibrahim, Mohamed, Ibrahim, Wadah, Idowu, Adetokunbo Idowu, Idrees, Muhammad, Idrees, Nauman, Iftikhar, Hina, Iftikhar, Mawara, Igwe, Chukwuemeka, Ijaz, Mohammad, Ikomi, Amaju, Iles, Clare, Iliodromiti, Stamatina, Ilsley, Mary, Ilves, Lorna, Imam-Gutierrez, La'ali, Imray, Christopher, Imtiaz, Haider, Ingham, Jack, Ingham, Julie, Ingham, Rory, Ingle, Tejas, Inglis, Jennifer, Ingram, Anne, Ingram, Luke, Inns, Peter, Inweregbu, Ken, Ionescu, Andreea Alina, Ionita, Ana, Iordanov, Ilian Petkov, Ipe, Anil, Iqbal, Madiha, Iqbal, Mohammed, Iqbal Sait, Faisal, Ireland, Jane, Irons, Robert, Irshad, Mohannad, Irshad, Muhammad S, Irvine, Janice, Irvine, Val, Irving, Robert, Ishak, Mina, Isherwood, Erica, Islam, Aminul, Islam, Samsul, Islim, Abdurrahman, Ismail, Ali, Ismail, Omar, Ison, Caroline, Israa, M'hamedi, Isralls, Sharon, Ivan, Monica, Ivenso, Chineze, Ivy, Ashleigh, Iwanikiw, Sophie, Ixer, Karen, Iyer, Menaka, Iyer, Mia, Jack, Calum, Jackson, Amanda, Jackson, Ben, Jackson, Beth, Jackson, Ella, Jackson, Helen, Jackson, Lauren, Jackson, Melanie, Jackson, Nicola, Jackson, Shane, Jacob, Patricia, Jacob, Reni, Jacques, Nicola, Jafar, Anisa, Jafferji, Daniel, Jaffery, Ali, Jagadish, Chandrashekar, Jagannathan, Vijay, Jagpal, Mandeep, Jaime, Fernandez Roman, Jain, Neemisha, Jain, Seema, Jain, Susan, Jaiswal, Sanjay, Jajbhay, Danyal, Jaki, Thomas, Jallow, Bintou, Jaly, Yusuf, Jamal, Sabine, Jamal, Zeba, Jameel, Yasmin, James, Albie, James, Christie, James, Kate, James, Lee, James, Linda, James, Mark, James, Nicholas, James, Olivia, James, Rebecca, James, Ruth, James, Tracy, Jameson, Jack, Jamison, Aaron, Jane, Phoebe, Janmohamed, Azara, Jansz, Sabrina, Japp, Deepa, Jardim, Victor, Jardine, Catherine, Jarnell, Emma, Jarvie, Ellie, Jarvis, Claire, Jarvis, Rosina, Jastrzebska, Patrycja, Javed, Hafsa, Jawad, Mays, Jawaheer, Lona, Jayachandran, Anu, Jayachandran, D, Jayakumar, Angelina, Jayaram, Deepak, Jayaram, Ravi, Jayasekera, Geeshath, Jayatilleke, Thilina, Jayebalan, Abi, Jeddi, Saman, Jeelani, Mohammad S, Jeffery, Katie, Jeffrey, Helen, Jeffrey, Rachel, Jeffreys, Nathan, Jeffs, Benjamin, Jegede, Debbie, Jemima, Taylor, Jenkin, Ifan, Jenkins, Alison, Jenkins, Christopher, Jenkins, David, Jenkins, Elinor, Jenkins, Sarah, Jenkins, Sian, Jenkins, Stephen, Jennings, Jacqui, Jennings, Louise, Jennings, Virginia, Jerome, Ellen, Jerry, Douglas, Jessup-Dunton, Ellen, Jesus Silva, Jorge Antonio, Jetha, Champa, Jethwa, Kishan, Jha, Roshan, Jhanji, Shaman, Jian, Khoo, Jiao, Zhixin, Jimenez, Laura, Jimenez Gil, Ana, Jith, Jithin, Joefield, Teishel, Johal, Navraj, Johannessen, Karine, Johari, Aisyah, John, Annie, John, Anu, John, Navin, Johns, Emma, Johns, Margaret, Johnson, Antoinette, Johnson, Emma, Johnson, Gillian, Johnson, Kathryn, Johnson, Katie, Johnson, Luke, Johnson, Mark, Johnson, Oliver, Johnston, Claire, Johnston, Janet, Johnston, Susan, Johnston, Victoria, Johnstone, Dawn, Johnstone, Ed, Johnstone, Janet, Joishy, Manohar, Jones, Adam, Jones, Alistair, Jones, Annabel, Jones, Ben, Jones, Bryony, Jones, Carys, Jones, Ceri, Jones, Charlotte, Jones, Christine E, Jones, Debra, Jones, Emily, Jones, Gareth, Jones, Geraldine, Jones, Jac, Jones, James, Jones, Jonathon, Jones, Julie, Jones, Kate E, Jones, Laura, Jones, Laura M, Jones, Louise, Jones, Mathew, Jones, Nicola, Jones, Paul, Jones, Rhianna, Jones, Ruth E, Jones, Samantha, Jones, Sophie, Jones, Stefanie, Jones, Steve, Jones, Taya, Jones, Tim, Jones, Tracey, Jonnalagadda, Ramya, Jordache, Rebecca, Jose, Sanal, Joseph, Anna, Joseph, P Aiden, Joseph, Rosane, Joseph, Sibet, Joshi, Dhaara, Joshi, Mehul, Joshi, Pratichi, Josiah, Benz, Joyce, Tiffany, Ju Wen Kwek, Adriel, Jude, Edward, Judge, Parminder, Juhl, Jessica, Jujjavarapu, Sirisha, Juniper, Mark, Juszczak, Edmund, Jyothish, Deepthi, Kabiru Dawa, Kasamu, Kacar, Mark, Kadam, Nikhil, Kahari, Rebecca, Kakoullis, Gail, Kala Bhushan, Azad, Kalayi, Richard J K, Kaliannan Periyasami, Roobala, Kallistrou, Efthymia, Kalsoom, Seika, Kam, Elisa, Kamara, John, Kamara, Mohamed, Kamath, Ajay, Kamath, Prakash, Kamath, Ravindra, Kamerkar, Siddharth Arun, Kametas, Nick, Kamfose, Musaiwale, Kane, Leia, Kankam, Osei, Kannan, Thogulava, Kant, Abhinav, Kapil, Vikas, Kapoor, Ritoo, Kapoor, Sonal, Kar, Sourjya, Kara, Janaka, Kark, Rona, Karkey, Abhilasha, Karunaratne, Nicholas, Kasianczuk, Natashja, Kasipandian, Vidya, Kassam, Rizwan, Kathirgamachelvam, Janarth, Katsande, Victoria, Kaul, Kulbinder, Kaur, Daljit, Kaur, Dervinder, Kaur, Jasmin, Kaur, Jaspreet, Kausar, Zunaira, Kawser, Mohammad A A, Kay, Andrea, Kay, Sarah, Kayappurathu, Jossy N, Kaye, Callum, Kazeem, Ahemd, Kearns, Rachel, Kearsley, Nichola, Keating, Joanne, Keating, John, Keating, Liza, Keddie-Gray, Elizabeth, Keenan, Natalie, Kefas, Jonathan, Kegg, Stephen, Keith, Laura, Keke, Uzoamaka, Kellett, Joanne, Kelly, Alison, Kelly, David, Kelly, Diane, Kelly, Dominic, Kelly, Emma, Kelly, Laura, Kelly, Martin, Kelly, Michael, Kelly, Rosalind, Kelly, Sinead, Kelly, Stephen, Kelly-Baxter, Mary, Keltos, Marketa, Kemp, Timothy, Kendall-Smith, Alexandra, Kennard, Sarah, Kennedy, Ann, Kennedy, James, Kennedy-Hay, Sophie, Kenny, Julia, Kent, Melanie, Keogan, Lynne, Keough, Alexander, Kerr, A, Kerr, Andrew, Kerrison, Caroline, Kerry, Anthony, Kerslake, Helen, Kerslake, Ian, Kerss, Helen, Keshet-Price, Jocelyn, Kestelyn, Evelyne, Keyte, Georgina, Khadar, Abdul, Khalid, Ali, Khalid, Muhammad U, Khalid, Syed, Khalil, Amir, Khalil, Asma, Khalil, Sijjad, Khan, Abubakar, Khan, Ali, Khan, Al-Imran, Khan, Arham, Khan, Asad, Khan, Aurangzeb, Khan, Burhan, Khan, Fatimah, Khan, Kausik, Khan, Malik Aamaz, Khan, Marria, Khan, Mehrunnisha, Khan, Mohammad, Khan, Nayeem, Khan, Omar, Khan, Rahila, Khan, Shabana, Khan, Shahul, Khan, Shoaib, Khan, Tasaduksultan, Khan, Waseem, Khatana, Usman Feroze, Khatri, Jibran, Khatri, Jyoti, Khatun, Hafiza, Khatun, Taslima, Kheia, Mena, Khera, Jacyntha, Khin, Htet Htet Ei, Khoja, Najaf, Khokhar, Kiran, Khurana, Chloe, Kibutu, Faith, Kidd, Andrew, Kidd, Michelle, Kidney, Joe, Kidney, Shane, Kieffer, Will, Kilbane, James, Kilby, Caroline, Killen, Eileen, Kilroy, Susan, Kim, Bomee, Kim, Jee Whang, Kimber, Sarah, King, Andy, King, Barbara, King, Jennifer, King, Kirsten, King, Rachel, King, Sarah, King, Victoria, King-Oakley, Emily, Kingsmore, Laura, Kinney, Fiona, Kiran, Sidra, Kirk, Jeremy, Kirk, Jodie, Kirkby, Amy, Kirkham, Emily, Kirkman, Gemma, Kirwan, Ursula, Kitching, Toby, Kitto, Laura, Kittridge, Lauren, Klaczek, Sarah, Kleemann, Frieder, Kmachia, Susan, Knapp, Christopher P, Knibbs, Lucy, Knight, Alicia, Knight, Fraser, Knight, Marian, Knight, Sarah, Knight, Steven, Knight, Tom, Knights, Ellen, Knights, Jane, Knolle, Martin, Knott, Carol, Knowles, Charlotte, Knowles, Karen, Knowles, Laurence, Knox, Emily, Knox, Lucy, Koch, Oliver, Kodituwakku, Ronan, Koduri, Gouri, Koirata, Aisha, Kolakaluri, Eirene, Kolodziej, Magdalena, Kolokouri, Eirini, Kon, Samantha, Konar, Niladri, Kononen, Mari, Konstantinidis, Athanasios, Koo, Hui Fen, Koopmans, Imogen, Kopyj, Emmanuela, Korcierz, Laura, Korolewicz, James, Koshy, George, Kosmidis, Chris, Kotecha, Jalpa, Kothandaraman, Easwari, Kouranloo, Koushan, Kousar'c, Rukhsana, Kousteni, Margarita, Kovac, Maja, Kozak Eskenazia, Alex, Krasauskas, Kestutis, Krishnamurthy, Raghu, Krishnamurthy, Vinodh, Krishnan, Manju, Krishnan, Hari, Krizak, Suzanne, Krupej, Sean, Kubisz-Pudelko, Agnieszka, Kudsk-Iversen, Soren, Kudzinskas, Aurimas, Kukadiya, Chirag, Kulkarni, Nainesha, Kumar, Aditi, Kumar, Mayur, Kumar, Ramesh, Kumar, Ravi, Kumar, Rita, Kumar, Rupa, Kumar, Satish, Kumar, Vimal, Kundu, Arun, Kunst, Heinke, Kurani, Amit, Kurdy, Mohammed, Kurian, Rincy, Kurmars, Vimal, Kuronen-Stewart, Cameron, Kusangaya, Ranganai Scott, Kushakovsky, Vlad, Kuverji, Apexa, Kyei-Mensah, Amma, Kyere-Diabour, Thyra, Kyi, Moe, Kyi, Nyan May, Kyle, Laura, Kyriaki, Karali-Tsilimpari, Labao, Julius, Lacey, Louise, Lack, Nikki, Ladlow, Emma, Lafferty, Heather, Laha, Shondipon, Lahane, Sushil, Lai, Clement, Lai, James, Laing, Robert, Laing-Faiers, Inez, Laity, Emily, Lakeman, Nicki, Lalloo, David, Lalloo, Fiona, Lam, Alison, Lamb, Fiona, Lamb, Lucy, Lamb, Thomas, Lambert, Pauline, Lameirinhas, Claudia, Lami, Mohammed Kadhim Gulam, Lamont, Holly, Lamparski, Michal, Lamrani, Djillali, Lanaghan, Christine, Lancona-Malcolm, Ivone, Landers, Geraldine, Landray, Martin J, Lane, Matthew, Lane, Nicholas, Lang, Alidih, Lang, Stephen, Langer, Daniel, Langley, Margaret, Langoya, Charles, Langthorne, Emily, Large, Taiya, Last, Anna, Latham, Scott, Latham-Mollart, John, Latheef, Afzal, Latt, Nang, Lau, Dawn, Lau, Eva, Laurenson, Myra, Law, Hou, Law, Jessica, Law, Penny, Law, Richard, Lawrence, Emma, Lawrence, Neil, Lawrie, Ryan, Lawson, Louise, Lay, Michael, Laycock, Christine, Layug, Reina, Lazo, Maria, Le, Vietland, Lea, Amelia, Lea, William, Leadbitter, Ian, Leahy, Thomas, Lean, Richard, Leandro, Lorna, Leaning, Darren, Leason, Sandra, Ledingham, Marie Anne, Lee, Emma, Lee, Hannah, Lee, Irish, Lee, Judith, Lee, Sam, Lee, Shi Han, Lee, Simon, Lee, Sindy, Lee, Stephanie, Lee, Tracey, Lee, Xiang, Lees, Diana, Lees, Jennifer, Legge, Helen, Leggett, Julian, Leigh-Ellis, Katie, Leitch, Nicky, Lekoudis, Eleni, Lemessy, Petula, Lemoine, Nicholas, Leng, Katy, Lennon, Katrina, Lennon, Liz, Leonard, Kelly, Leong, Wen, Leopold, Nicky, Lepiarczyk, Oskar, Leslie, Isla, Lester, Eleni, Levell, Emma, Levett, Chris, Lewin, Alice, Lewis, Alison, Lewis, David, Lewis, Dee, Lewis, Joanne, Lewis, Joseph, Lewis, Kathryn, Lewis, Keir, Lewis, Leon, Lewis, Marissa, Lewis, Rob, Lewis, Robert, Lewis-Clarke, Catherine, Lewiston, Katherine, Lewszuk, Adam, Lewthwaite, Penny, Ley, Samantha, Liao, Angela, Licence, Victoria, Lieberman, David, Liebeschuetz, Susan, Lightfoot, Nicky, Lillie, Patrick, Lim, Ben, Lim, Carys, Lim, Ee Thong, Lim, Ivy, Lim, Terence, Lim, Wei Shen, Lim, Wilson, Limb, James, Limbu, Usha, Linares, Christian, Linden, Dermot, Lindergard, Gabriella, Lindley, Kate, Lindsay, Charlotte, Lindsay, Emily, Lindsay, Max, Lindsay- Clarke, Helen, Ling, Mirella, Lingam, Claire, Linkson, Linette, Linney, Mike, Linsell, Louise, Lippold, Conrad, Lipscomb, George, Lipscomb, Karen, Lipskis, Laura, Lisboa, Ana, Lister, Evangeline, Little, Jeff, Little, Sam, Liu, Xuedi, Llanera, Daniel K, 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Claire, McNeill, Shea, McNelis, Una, McNulty, Melanie, McNulty, Roisin, McParland, Christopher, McPhail, Mark, McQueen, Alison, McSkeane, Anna, McSorland, Denise, McTaggart, Gini, McTaggart, Jacqueline, Mead, Joanna, Meadows, Emma, Meakin, Olivia, Mearns, Ben, Mearns, Claire, Mears, Kim, Mears, William, Meda, Manjula, Mediana, Ayren, Medine, Ross, Medveczky, Thomas, Meehan, Sharon, Meeks, Emily, Megan, Abbi, Meghani, Nevan, Meghjee, Salim, Mehra, Rohan, Meiring, James, Mejri, Rayane, Melander, Sabina, Melinte, Adriana-Stefania, Mellor, Francesca, Mellor, Samantha, Mellor, Zoe, Mellows, Katrina, Melnic, Vladimir, Melville, Alice, Melville, Julie, Membrey, Helen, Mencias, Mark, Mendonca, Cheryl, Mentzer, Alexander, Menzies, Dan, Mepham, Sue, Mercer, Oliver, Mercer, Pauline, Merchant, Arwa, Merchant, Fatema, Mercioniu, Mihaela, Meredith, Megan, Merida Morillas, Marta, Merrick, Blair, Merritt, Jack, Merritt, Simon, Merwaha, Ekta, Message, Simon, Metcalf-Cuenca, Gabriel, Metcalfe, Benjamin, Metcalfe, Kneale, Metherell, Stella, Metryka, Alexsandra, Mew, Louise, Meyrick, Simon, Mguni, Nhlanhla, Miah, Atiqa, Miah, Jagrul, Miah, Nahima, Mic, Gabriela, Micallef, Dariush,