Journal of Mechanics in Medicine and Biology. Dec 2015, Vol. 15 Issue 06
Orthopedic surgery -- Methods, Orthopedic surgery -- Analysis, Rapid prototyping -- Methods, and Rapid prototyping -- Analysis
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1142/S0219519415400503 Byline: LI-QIANG ZHI, MENG LI, KAI LIU, XING MA Advanced three-dimensional (3D) models have played more and more essential roles in orthopedics surgical interventions. In order to improve the clinical outcomes of knee surgery (KS) including minimally invasive knee surgery (MIKS), the melted extrusion modeling (MEM), a rapid prototyping (RP) technique, was used efficiently to fabricate real life-size 3D physical models of interesting knees. The applications and advantages of the tangible RP-constructed 3D models in KS were elucidated in this study. As a result, better preparation including optimal preoperative planning was made so that KS could be performed in an accurate, safe and fast manner for each case. Besides, the surgical skills of MIKS were substantially improved. Therefore, the results suggest that KS can benefit much from the advanced 3D modeling technique.
Journal of Mechanics in Medicine and Biology. Dec 2011, Vol. 11 Issue 05, 993
Tissue engineering -- Analysis and Rapid prototyping -- Analysis
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1142/S0219519411004848 Byline: CHIH-HAO CHEN, JYH-PING CHEN, MING-YIH LEE The purpose of this study was to investigate the attachment and proliferation of cells on selective laser-sintered (SLS) polycaprolactone (PCL) scaffolds coated with gelatin for cartilage tissue engineering using chondrocytes isolated from the articular cartilage of swine. Scaffolds without modification were used as control groups. Cell proliferation was measured by cell count 1, 3 and 5 days after cell seeding into the scaffolds. The biocompatibility of the scaffold was examined by scanning electron microscopy (SEM). The PCL scaffolds coated with gelatin had higher hydrophilicity. The results provided a useful strategy for modifying the microenvironments to increase cell attachment, growth and the formation of extracellular matrix on scaffolds for cartilage tissue engineering.
Journal of Mechanics in Medicine and Biology. August 2015, Vol. 15 Issue 04
CAD/CAM software, CAD software, Computer-aided design -- Analysis, Rapid prototyping -- Analysis, CAD-CAM systems -- Computer programs, and CAD-CAM systems -- Analysis
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1142/S021951941550058X Byline: MORSHED ALAM, IMTIAZ AHMED CHOUDHURY, AZUDDIN BIN MAMAT, SAJJAD HUSSAIN Traditional design and manufacturing methods of ankle foot orthosis (AFO) involve manual techniques e.g., casting and molding of the limbs and often depend on trial and error. Three-dimensional scanning allows computer aided design (CAD) tools to be incorporated, however, both approaches rely on the external model of the limb. To design AFO with articulated joint, precise alignment of mechanical and anatomical joint axes is imperative. It is difficult to infer joint axis from external model as it is partially specified by the skeletal structure. In this article, a computer integrated design approach of an articulated AFO has been demonstrated. CAD model of the AFO was developed for a healthy subject's left leg based on the 3D models of skeleton and soft tissue of the limb. Components of the AFO were fabricated by rapid prototyping and CNC machining. The design approach is faster than the traditional techniques and also facilitates exact positioning of articulated ankle joint. The gait analysis indicates that the subject's ankle had to overcome lesser resistance with the custom made AFO compared to a pre-fabricated AFO. Simultaneous viewing of exterior and skeletal geometry might help the clinicians modify the design to enhance performance of the orthotic.