Ma, Kristin R, Juran, Cassandra M, and Almeida, Eduardo
American Society for Gravitational and Space Research (ASGSR) 2019; Nov 20, 2019 - Nov 23, 2019; Denver, CO; United States
The NASA Bioculture System is an advanced cell culture closed-loop system containing highly automated flowpaths designed to conduct long term biology experiments on ISS with earth remote controllable medium flow, temperature, gas composition, medium exchange, cell sampling and fixation. This technology was already demonstrated with successful cardiomyocyte and osteocyte cultures experiments onboard the ISS and is now supporting NASA PI science. The Bioculture System, however, can only support 10 cassettes with disposable flowpaths, each containing a single hollow fiber bioreactor with a culture capacity of about 2ml. This constraint not only severely limits the number of investigators that can conduct experiments in space, but also subjects the experiments to limitations in the number of replicates and conditions that can be studied. To address these limitations, we sought a novel design solution to maximize the number of separate bioreactor cultures and volume that can be conducted simultaneously. To this end we designed, prototyped, and are now testing a six-Vitvo 3D Matrix 2ml bioreactor insert that replaces the conventional Bioculture System hollow fiber bioreactor. This design will allow the Bioculture System to support up to 60 different bioreactors and samples at once. Specifically, the novel gas-tight containment housing insert contains six COTS Rigenerand VITVO bioreactors stacked on each side of a heat sink powered by the existing heating element and pair of temperature sensors. Medium will be distributed into each bioreactor's cell-free chamber via its built-in Luer connector, then across the 3D matrix to the cell chamber, dissipating laminar flow and limiting fluid shear stresses that might mechanostimulate cell cultures. Gas (5% CO2 in air) will be supplied directly to the bioreactor gas-tight housing for exchange via the bioreactor flat-surface gas-permeable membranes, eliminating the need for the existing Bioculture System cassette oxygenator. If successfully implemented on ISS, this new multi-bioreactor insert for the Bioculture System has the potential to make real-time cell science experimentation in space more efficient and accessible to more investigators.
Conservation Biology. Dec 2019, Vol. 33 Issue 6, p1448, 3 p.
***** No abstract is available for this article. Article Note: Article impact statement: Web-application development frameworks enable the creation of decision-support tool prototypes for actionable conservation science. CAPTION(S): Table 1. List of web-application development frameworks that might be useful for conservation scientists. Byline: Denis Valle, Kok Ben Toh, Justin Millar
Lifson, Miles T, Kopardekar, Parimal H, Nag, Sreeja, Marker, Nimesh A, and Murakami, David D
International Astronautical Congress (IAC) Conference; Oct 21, 2019 - Oct 25, 2019; Washington, DC; United States
Space Transportation and Safety
Current state of the art in Space Traffic Management (STM) relies on a handful of providers for surveillance and collision prediction, and manual coordination between operators. Neither is scalable to support the expected 10x increase in spacecraft population in less than 10 years, nor does it support automated manuever planning. We present a software prototype of an STM architecture based on open Application Programming Interfaces (APIs), drawing on previous work by NASA to develop an architecture for low-altitude Unmanned Aerial System Traffic Management. The STM architecture is designed to provide structure to the interactions between spacecraft operators, various regulatory bodies, and service suppliers, while maintaining flexibility of these interactions and the ability for new market participants to enter easily. Autonomy is an indispensable part of the proposed architecture in enabling efficient data sharing, coordination between STM participants and safe flight operations. Examples of autonomy within STM include syncing multiple non-authoritative catalogs of resident space objects, or determining which spacecraft maneuvers when preventing impending conjunctions between multiple spacecraft. The STM prototype is based on modern micro-service architecture adhering to OpenAPI standards and deployed in industry standard Docker containers, facilitating easy communication between different participants or services. The system architecture is designed to facilitate adding and replacing services with minimal disruption. We have implemented some example participant services (e.g. a space situational awareness provider/SSA, a conjunction assessment supplier/CAS, an automated maneuver advisor/AMA) within the prototype. Different services, with creative algorithms folded into then, can fulfil similar functional roles within the STM architecture by flexibly connecting to it using pre-defined APIs and data models, thereby lowering the barrier to entry of new players in the STM marketplace. We demonstrate the STM prototype on a multiple conjunction scenario with multiple maneuverable spacecraft, where an example CAS and AMA can recommend optimal maneuvers to the spacecraft operators, based on a predefined reward function. Such tools can intelligently search the space of potential collision avoidance maneuvers with varying parameters like lead time and propellant usage, optimize a customized reward function, and be implemented as a scheduling service within the STM architecture. The case study shows an example of autonomous maneuver planning is possible using the API-based framework. As satellite populations and predicted conjunctions increase, an STM architecture can facilitate seamless information exchange related to collision prediction and mitigation among various service applications on different platforms and servers. The availability of such an STM network also opens up new research topics on satellite maneuver planning, scheduling and negotiation across disjoint entities.
3D printing -- Usage, Thermoplastics -- Production processes, Thermoplastics -- Innovations, Plastics industry -- Production processes, and Plastics industry -- Innovations
The laborious process of product development is changing. The evolution of rapid prototyping, 3D printing, and additive manufacturing will continue to affect the process for the better, developing accurate and [...]
Imagine standing on the surface of an alien planet or satellite. High in the sky, a soft breeze is interrupted by the whistling sound of a tiny probe sent from Earth to study the atmosphere, or to land on some high-value target on the surface. Now imagine that this probe is followed by a dozen others, all entering in distributed locations throughout the geographic landscape. These probes are systematically and methodically being released from an orbiting spacecraft, perhaps having arrived months in advance. Or maybe the probes themselves are released systematically months in advance by and approaching mother-ship. Although probes have been sent to celestial neighbors before, what is unique is that these new vehicles had their genesis on the highly popular Cubesat specification My dream is to make spaceflight so mundane, we can actually routinely leave the bounds of our planet to explore en masse our solar system. For that, we must create systems that allow us to bring space exploration within the realm of our everyday lives. No longer exquisite systems but just good enough, where failure is an option and a new opportunity.
Policy & Practice. June 2019, Vol. 77 Issue 3, p12, 4 p.
Government regulation, Company business management, Human services -- Laws, regulations and rules, Human services -- Psychological aspects, Pilot projects -- Management, Pilot projects -- Psychological aspects, Policy sciences -- Methods, Policy sciences -- Psychological aspects, and Prototypes (Psychology) -- Analysis
"I didn't know it would take this long, or what the next stepes were. I waited a long time and had to hurry to complete some forms before a deadline. [...]
Sieberth, Till, Dobay, Akos, Affolter, Raffael, and Ebert, Lars
Forensic Science International. Dec 2019, Vol. 305, 110006
Virtual reality technology, Interactive technology, Crime reconstruction -- Methods, Virtual reality -- Usage, Interactive computer systems -- Usage, and Interactive media -- Usage
Keywords Virtual reality; 3D reconstruction; Crime scene investigation Highlights * For the use of virtual reality in forensic virtual scenes require a set of tools. * Interaction and Modification in Virtual Crime Scenes allow for discussion of the scenes. * Already a small number of tools in virtual scenes support a variety of forensic applications. Abstract Virtual reality is recently finding its way in forensic work. The required 3D data is nowadays a standard dataset available in many cases, from homicide to traffic collisions, including not only data from the scene but also of weaponry and involved persons. Current investigations use these 3D data to replicated the incident and as discussion base for forensic personal. However, modifying the scene on a 2D viewport is often cumbersome due to the loss of the third dimension. Also to perform the modifications on the scene a 3D operator is often required. Virtual reality might improve this step by its easy use and by visualising the third dimension. This publication presents a variety of tools which can be used in forensic investigations. Additionally to the tools, examples of forensic use of these tools will be presented, showing that already a small number of tools support a variety of forensic applications. Author Affiliation: (a) Institute of Forensic Medicine, University of Zurich, Winterthurerstrasse 190/52, CH-8057, Zurich, Switzerland (b) 3D Zentrum Zurich, University of Zurich, Winterthurerstrasse 190/52, CH-8057, Zurich, Switzerland * Corresponding author at: Institute of Forensic Medicine, University of Zurich, Winterthurerstrasse 190/52, CH-8057, Zurich, Switzerland. Article History: Received 4 June 2019; Revised 6 October 2019; Accepted 21 October 2019 Byline: Till Sieberth [firstname.lastname@example.org] (a,b,*), Akos Dobay (a), Raffael Affolter (a), Lars Ebert (a,b)
Quotation are invited for Supply of -Rapid prototyping machine-3D Printer FDM Technology /Raise 3D Pro 2 Plus etc Major organization : BIRLA INSTITUTE OF TECHNOLOGY Address : Mesra,Ranchi-835215 Jharkhand Country [...]
Tenders are invited for Rapid prototyping machine as per tender documents Tender Type: Open tender Form Of Contract: Supply Tender Category: Goods No. of Covers: 2 General Technical Evaluation Allowed: [...]
Tenders are invited for Metal rapid prototyping of aero engine model with accessories Product Category: Miscellaneous goods EMD Amount (INR): 60,980 Tender Type: Open tender Bid Validity(Days): 180 Period Of [...]
Tenders are invited for Large format duel extruder rapid prototyping system. Details are as per rfp. Product Category: Miscellaneous goods EMD Amount (INR): 1,00,000 Tender Type: Open tender Bid Validity(Days): [...]