Chemistry - A European Journal; 11/20/2020, Vol. 26 Issue 65, p15016-15022, 7p
ORGANIC synthesis, SPECTROMETRY, ASTRONOMICAL observations, and NUCLEAR magnetic resonance spectroscopy
Phenylmethanimine is an aromatic imine with a twofold relevance in chemistry: organic synthesis and astrochemistry. To tackle both aspects, a multidisciplinary strategy has been exploited and a new, easily accessible synthetic approach to generate stable imine‐intermediates in the gas phase and in solution has been introduced. The combination of this formation pathway, based on the thermal decomposition of hydrobenzamide, with a state‐of‐the‐art computational characterization of phenylmethanimine laid the foundation for its first laboratory observation by means of rotational electric resonance spectroscopy. Both E and Z isomers have been accurately characterized, thus providing a reliable basis to guide future astronomical observations. A further characterization has been carried out by nuclear magnetic resonance spectroscopy, showing the feasibility of this synthetic approach in solution. The temperature dependence as well as possible mechanisms of the thermolysis process have been examined. [ABSTRACT FROM AUTHOR]
Frías, María, Cieślik, Wioleta, Fraile, Alberto, Rosado‐Abón, Anielka, Garrido‐Castro, Alberto F., Yuste, Francisco, and Alemán, José
Chemistry - A European Journal; Aug2018, Vol. 24 Issue 43, p10906-10933, 28p
ORGANOCATALYSIS, ORGANIC chemistry, SUPRAMOLECULAR chemistry, NATURAL products, and CHEMICAL reactions
Abstract: Organocatalysis is a growing area that is benefiting from advances in many fields. Its implementation has begun in areas such as supramolecular chemistry, organic chemistry and natural product synthesis. While a considerable number of important publications in the field of organocatalytic Mukaiyama‐type additions have been reported, they are yet to be fully covered in a review. Therefore, we would like to highlight the applications of various kinds of organocatalysts in Mukaiyama‐type reactions, while also including the vinylogous Mukaiyama variation. Herein we describe and discuss the development and current state of the art of the organocatalytic Mukaiyama reaction, vinylogous Mukaiyama and related reactions. [ABSTRACT FROM AUTHOR]
SOIL chemistry, WATER chemistry, SPATIAL variation, and WATERSHEDS
The article presents the study which examines the spatial and temporal variability in surface water chemistry, organic soil chemistry and hydrologic indicators at three poor-fen complexes in two boreal catchments in Northern Alberta. The examination is intended to offer insights into the dominant controls on surface water chemistry. The relation between exchangeable base saturation and potential of hydrogen (pH) of organic soils with surface water chemistry at two of the fen complexes is cited.
Five departments, one common goal:For the past 100 years, the Max‐Planck‐Institut für Kohlenforschung in Mülheim an der Ruhr has focused above all on chemical catalysis, and this is more true today than ever. Researchers in heterogeneous, homogeneous, and biocatalysis, organometallic chemistry, organic synthesis, as well as theoretical chemistry are occupied with the catalytic transformation of raw materials and pure compounds with the highest possible chemo‐, regio‐, and stereoselectivity under conditions that maximize the use of natural resources. [ABSTRACT FROM AUTHOR]
BUSINESS partnerships, PHARMACEUTICAL chemistry, DRUG development, NATURAL products, and BUSINESS enterprises
The article presents the author's views on the increasing partnership between academic and industrial enterprises of pharmaceuticals with an aim of improving drug discovery and development. Various issues discussed includes challenges faced by academic-industrial partnerships, structure of medicinal chemistry, organic synthesis and use of natural products in drug development.