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Information and communication sciences, Sciences de l'information communication, Documentation, Sciences exactes et technologie, Exact sciences and technology, Sciences et techniques communes, Sciences and techniques of general use, Sciences de l'information. Documentation, Information science. Documentation, Technologie de la communication et de l'information, Information and communication technologies, Technologies de l'information: supports, équipements, Information technologies: storage media, equipment, Applications (par exemple: numérisation,...), Applications (e.g. Digitizing,...), Ressources internet (portails, blogs, wikis,...), Internet resources (portals, blogs, wikis,...), Sciences de l'information et de la communication, Information and communication sciences, Applications, Ressources internet (portails, blogs, wikis,…), Internet resources (portals, blogs, wikis,…), Réseau social, Social network, Red social, Vie privée, Private life, Vida privada, and Vie publique

[ point de vue ] Les nouveaux médias numériques ontsensiblementmodifiél'acceptiontraditionnelledes concepts de vie privée et de vie publique. Née du développement des réseaux sociaux, cette rupture a généré de nouvelles « sphères publiques médiatées » au sein desquelles se déploie désormais une part de notre vie quotidienne. Une évolution de l'espace public qui appelle un accompagnement des jeunes, particulièrement présents et investis dans ces réseaux numériques.

Biochemistry, molecular biology, biophysics, Biochimie, biologie moléculaire, biophysique, Microbiology, infectious diseases, Microbiologie, maladies infectieuses, Virology, Virologie, Sciences biologiques et medicales, Biological and medical sciences, Sciences biologiques fondamentales et appliquees. Psychologie, Fundamental and applied biological sciences. Psychology, Microbiologie, Microbiology, Virologie, Virology, Divers, Miscellaneous, Hepadnaviridae, Orthohepadnavirus, Virus, Antigène HBs, Hepatitis B surface antigen, Antígeno HBs, Virus hépatite B, and Hepatitis B virus

Native hepatitis B surface antigen (HBsAg) spontaneously assembles into 22-nm subviral particles. The particles are lipoprotein micelles, in which HBsAg is believed to span the lipid layer four times. The first two transmembrane domains, TM1 and TM2, are required for particle assembly. We have probed the requirements for particle assembly by replacing the entire first or third TM domain of HBsAg with the transmembrane domain of HIV gp41. We found that either TM domain of HBsAg could be replaced, resulting in HBsAg-gp41 chimeras that formed particles efficiently. HBsAg formed particles even when both TM1 and TM3 were replaced with the gp41 domain. The results indicate remarkable flexibility in HBsAg particle formation and provide a novel way to express heterologous membrane proteins that are anchored to a lipid surface by their own membrane-spanning domain. The membrane-proximal exposed region (MPER) of gp41 is an important target of broadly reactive neutralizing antibodies against HIV-1, and HBsAg-MPER particles may provide a good platform for future vaccine development.

Pediatrics, Pédiatrie, Psychology, psychopathology, psychiatry, Psychologie, psychopathologie, psychiatrie, Sciences biologiques et medicales, Biological and medical sciences, Sciences medicales, Medical sciences, Psychopathologie. Psychiatrie, Psychopathology. Psychiatry, Techniques et méthodes, Techniques and methods, Méthodologie. Expérimentation, Methodology. Experimentation, Psychologie. Psychanalyse. Psychiatrie, Psychology. Psychoanalysis. Psychiatry, PSYCHOPATHOLOGIE. PSYCHIATRIE, Homme, Human, Hombre, Adolescent, Adolescente, Harcèlement moral, Psychological harassment, Acoso moral, Internet, Intimidation, Bullying, intimidación, Méthode mesure, Measurement method, Método medida, Méthodologie, Methodology, Metodología, Technologie information communication, Information communication technology, Nueva tecnología información comunicación, Victimisation, Victimization, Victimización, Cyberbullying, and Measurement

Purpose: To inform the scientific debate about bullying, including cyberbullying, measurement. Methods: Two split-form surveys were conducted online among 6―17-year-olds (n = 1,200 each) to inform recommendations for cyberbullying measurement. Results: Measures that use the word bully result in prevalence rates similar to each other, irrespective of whether a definition is included, whereas measures not using the word bully are similar to each other, irrespective of whether a definition is included. A behavioral list of bullying experiences without either a definition or the word bully results in higher prevalence rates and likely measures experiences that are beyond the definition of bullying. Follow-up questions querying differential power, repetition, and bullying over time were used to examine misclassification. The measure using a definition but not the word bully appeared to have the highest rate of false positives and, therefore, the highest rate of misclassification. Across two studies, an average of 25% reported being bullied at least monthly in person compared with an average of 10% bullied online, 7% via telephone (cell or landline), and 8% via text messaging. Conclusions: Measures of bullying among English-speaking individuals in the United States should include the word bully when possible. The definition may be a useful tool for researchers, but results suggest that it does not necessarily yield a more rigorous measure of bullying victimization. Directly measuring aspects of bullying (i.e., differential power, repetition, over time) reduces misclassification. To prevent double counting across domains, we suggest the following distinctions: mode (e.g., online, in-person), type (e.g., verbal, relational), and environment (e.g., school, home). We conceptualize cyberbullying as bullying communicated through the online mode.

Psychology, psychopathology, psychiatry, Psychologie, psychopathologie, psychiatrie, Sciences exactes et technologie, Exact sciences and technology, Sciences appliquees, Applied sciences, Informatique; automatique theorique; systemes, Computer science; control theory; systems, Logiciel, Software, Systèmes informatiques et systèmes répartis. Interface utilisateur, Computer systems and distributed systems. User interface, Sciences biologiques et medicales, Biological and medical sciences, Sciences medicales, Medical sciences, Psychopathologie. Psychiatrie, Psychopathology. Psychiatry, Etude clinique de l'adulte et de l'adolescent, Adult and adolescent clinical studies, Troubles du comportement social. Comportement criminel. Délinquance, Social behavior disorders. Criminal behavior. Delinquency, Psychologie. Psychanalyse. Psychiatrie, Psychology. Psychoanalysis. Psychiatry, PSYCHOPATHOLOGIE. PSYCHIATRIE, Homme, Human, Hombre, Interaction sociale, Social interaction, Interacción social, Adolescent, Adolescente, Communication médiatisée ordinateur, Computer mediated communication, Communicación mediatizada computador, Comportement rendez vous, Dating behavior, Conducta cita, Messagerie instantanée, Instant messaging, Mensajería instantánea, Trouble du comportement social, Social behavior disorder, Trastorno comportamiento social, Violence, and Violencia

Teen dating violence (TDV) is a serious form of youth violence that youth fairly commonly experience. Although youth extensively use computer-mediated communication (CMC), the epidemiology of CMC-based TDV is largely unknown. This study examined how perpetration of psychological TDV using CMC compares and relates to perpetration using longer-standing modes of communication (LSMC; e.g., face-to-face). Data from the national Growing up with Media study involving adolescents aged 14―19 collected from October 2010 to February 2011 and analyzed May 2012 are reported. Analyses focused on adolescents with a history of dating (n = 615). Forty-six percent of youth daters had perpetrated psychological TDV. Of those who perpetrated in the past 12 months, 58% used only LSMC, 17% used only CMC, and 24% used both. Use of both CMC and LSMC was more likely among perpetrators who used CMC than among perpetrators who used LSMC. In addition, communication mode and type of psychological TDV behavior were separately related to frequency of perpetration. Finally, history of sexual intercourse was the only characteristic that discriminated between youth who perpetrated using different communication modes. Results suggest that perpetration of psychological TDV using CMC is prevalent and is an extension of perpetration using LSMC. Prevention should focus on preventing perpetration of LSMC-based TDV as doing so would prevent LSMC as well as CMC-based TDV.

Cognition, Documentation, Computer science, Informatique, Sciences exactes et technologie, Exact sciences and technology, Sciences et techniques communes, Sciences and techniques of general use, Sciences de l'information. Documentation, Information science. Documentation, Sciences de l'information et des bibliothèques. Etude d'ensemble, Library and information science. General aspects, Bibliométrie. Scientométrie. Evaluation, Bibliometrics. Scientometrics. Evaluation, Sciences de l'information et de la communication, Information and communication sciences, Bibliométrie. Scientométrie, and Bibliometrics. Scientometrics

When information practices are understood to be shaped by social context, privilege and marginalization alternately affect not only access to, but also use of information resources. In the context of information, privilege, and community, politics of marginalization drive stigmatized groups to develop collective norms for locating, sharing, and hiding information. In this paper, we investigate the information practices of a subcultural community whose activities are both stigmatized and of uncertain legal status: the extreme body modification community. We use the construct of information poverty to analyze the experiences of 18 people who had obtained, were interested in obtaining, or had performed extreme body modification procedures. With a holistic understanding of how members of this community use information, we complicate information poverty by working through concepts of stigma and community norms. Our research contributes to human information behavior scholarship on marginalized groups and to Internet studies research on how communities negotiate collective norms of information sharing online.