Synthesis and surface modification of polyurethanes with chitosan for antibacterial properties
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- Authors:
- KARA, Filiz
AKSOY, Eda Ayse
YUKSEKDAG, Zehranur
HASIRCI, Nesrin
AKSOY, Serpil - Author Affiliations:
- Department of Chemistry, Faculty of Science. Gazi University, 06500 Ankara, Turkey
Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey
BIOMATEN, Center of Excellence in Biomaterials and Tissue Engineering, Middle East Technical University, Dumlupmar Bulvan, No:1, 06800 Cankaya, Ankara, Turkey
Department of Biology, Biotechnology Laboratory, Faculty of Science, Gazi University, 06500 Ankara, Turkey
Department of Chemistry, Faculty of Arts and Sciences, Middle East Technical University, 06800 Ankara, Turkey - Source:
- Carbohydrate polymers. 112:39-47
- Publication Date:
- 2014-01-01
- Language:
- English
- Abstract:
- Surface modification and providing antibacterial properties to the materials or devices are getting great attention especially in the last decades. In this study, polyurethane (PU) films were prepared by synthesizing them in medical purity from toluene diisocyanate and polypropylene ethylene glycol without using any other ingredients and then the film surfaces were modified by covalent immobilization of chitosan (CH) which has antibacterial activity. CH immobilized PU films (PU-CH) were found to be more hydrophilic than control PU films. Electron Spectroscopy for Chemical Analysis (ESCA) and Atomic Force Microscopy (AFM) analyses showed higher nitrogen contents and rougher surface topography for PU-CH compared to PU films. Modification with CH significantly increased antibacterial activity against Gram positive (Staphylococcus aureus) and Gram negative (Pseudomonas aeruginosa) bacteria. It was observed that the number of bacteria colonies were less about 102-105 CFU/mL and number of attached viable bacteria decreased significantly after CH modification of PU films.
- Notes:
- Physical chemistry of polymers<br><br>Surgery (generalities). Transplants, organs and tissues grafting. Graft pathologies
- Subjects:
- Polymers, paint and wood industries
Polymères, industries des peintures et bois
Sciences exactes et technologie
Exact sciences and technology
Sciences appliquees
Applied sciences
Physicochimie des polymeres
Physicochemistry of polymers
Polymères d'origine naturelle
Natural polymers
Amidon et polyosides divers
Starch and polysaccharides
Polymères organiques
Organic polymers
Propriétés et caractérisation
Properties and characterization
Propriétés biologiques
Biological properties
Sciences biologiques et medicales
Biological and medical sciences
Sciences medicales
Medical sciences
Chirurgie (generalites). Transplantations, greffes d'organes et de tissus. Pathologie des greffons
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technologie. Biomatériaux. Equipements
Technology. Biomaterials. Equipments
Bactérie
Bacteria
Micrococcaceae
Micrococcales
Oside polymère
Oside polymer
Osido polímero
Propriété biologique
Biological properties
Propiedad biológica
Propriété surface
Surface properties
Propiedad superficie
Pseudomonadaceae
Pseudomonadales
Adhérence cellulaire
Cell adhesion
Adherencia celular
Antibactérien
Antibacterial agent
Antibacteriano
Bactéricidie
Bactericidal effect
Bactericidia
Biomatériau
Biomaterial
Chitosane
Chitosan
Quitosano
Copolymère greffé
Graft copolymer
Copolímero injertado
Copulation chimique
Chemical coupling
Copulación química
Etheruréthanne polymère
Etherurethane polymer
Eteruretano polímero
Etude expérimentale
Experimental study
Estudio experimental
Mouillabilité
Wettability
Remojabilidad
Préparation
Preparation
Preparación
Pseudomonas aeruginosa
Réaction surface
Surface reaction
Reacción superficie
Staphylococcus aureus
Topographie surface
Surface topography
Traitement par plasma
Plasma assisted processing
Traitement surface
Surface treatment
Tratamiento superficie
Uréthanne copolymère
Urethane copolymer
Uretano copolímero
Energie libre surface
Antibacterial
Bacterial adhesion
Polyurethane
Surface modification - Format:
- Academic Journal
- Database:
- PASCAL Archive
- Journal:
- Carbohydrate polymers
- Volume:
- 112
- Page Start:
- 39
- Page Count:
- 9
- ISSN:
- 01448617
- Publisher:
- Kidlington: Elsevier, 2014.
- Document Type:
- Article
- Physical Description:
- print, 1 p.1/4
