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1 online resource (1 streaming video file (46 min.) : color, sound).
  • Contents: Importance of analgesia in laboratory animal sciences
  • Pain assessment
  • Perioperative pain treatment
  • Local and regional anesthesia or analgesia
  • Anesthesia monitoring
  • Post-anesthesia.
254 p. ; 21x28 cm
El programa de la OCDE sobre Análisis de los resultados medioambientales proporciona una evaluación independiente del progreso de los países para cumplir los compromisos nacionales e internacionales en materia de políticas ambientales junto con recomendaciones relevantes a dichas políticas. Las evaluaciones están dirigidas para promover el aprendizaje entre pares, estimular una mayor rendición de cuentas entre países y ante la opinión pública y para que los países mejoren su comportamiento individual y colectivo en la gestión del medio ambiente. Los análisis están avalados por un amplio espectro de datos económicos y ambientales. Cada ciclo de Análisis de los resultados medioambientales cubre todos los países miembros de la OCDE y algunos países socios. Entre las más recientes evaluaciones se encuentran: Islandia (2014), Suecia (2014) y Colombia (2014). Este informe es el tercer análisis de los resultados medioambientales de España. Evalúa el progreso hacia el desarrollo sostenible y el crecimiento verde y se centra en políticas sobre biodiversidad y resultados medioambientales del sector industrial. Contenido: Parte I. Progreso hacia el desarrollo sostenible Capítulo 1. Principales tendencias medioambientales Capítulo 2. Entorno decisorio Capítulo 3. Hacia el crecimiento verde Parte II. Progreso hacia objetivos medioambientales seleccionados Capítulo 4. Conservación y uso sostenible del medio ambiente marino y terrestre Capítulo 5. Resultados medioambientales del sector industrial
1 online resource (vi, 398 p.) : ill. (some col.). Digital: text file; PDF.
  • The Era of Big Data: From Data-driven Research to Data-driven Clinical Care.- Biostatistics, data mining and computational modeling.- Gene expression and profiling.- The next generation sequencing and applications in clinical research.- Clinical epigenetics and epigenomics.- Proteomic profiling: Data mining and analyses.- Targeted metabolomics: the next generation of clinical chemistry!?.- Clinical bioinformatics for biomarker discovery in targeted metabolomics.- Metagenomic Profiling, Interaction of Genomics with Meta-genomics.- Clinical Epigenetics and Epigenomics.- Integrative Biological Databases.- Standards and Regulations for (Bio)Medical Software.- Clinical applications and systems biomedicine.- Key Law and Policy Considerations for Clinical Bioinformaticians.- Challenges and Opportunities in Clinical Bioinformatics.- Heterogeneity of Hepatocellular Carcinoma.
  • (source: Nielsen Book Data)
This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.
(source: Nielsen Book Data)
1 online resource (XVI, 254 p. 292 ill., 55 illus. in color.) : online resource. Digital: text file; PDF.
  • Data and Methods
  • Climate Change Historical Simulations and Projections
  • Comparisons among Multi-model Ensemble Methods
  • Responsibility for Historical Climate Change Induced from Developed and Developing World Anthropogenic Carbon Emissions
  • Responsibility for Historical Climate Change Induced from Developed and Developing World Anthropogenic Sulfur Emissions
  • Transferred Responsibility for Historical Climate Change Induced from Carbon Trade between Developed and Developing World.
This atlas and reference resource assembles the latest research findings on the responsibility and obligation of human society for historical climate change. It clearly and quantitatively estimates to what extent the developed and developing world are responsible for historical climate change with regard to anthropogenic carbon and sulfur emissions as well as global carbon trade, and so provides a potential tool to address the controversial issue of carbon emission reduction in international climate negotiations. Since the quantitative attribution of historical climate change is calculated based on CMIP5 models, the fidelity of these models in representing the observed climate change is also evaluated. In addition to evaluation, future climate change based on CMIP5 models is also shown both on global and regional scales (especially for China and its surrounding areas ) in terms of surface air temperature, precipitation, sea surface temperature, atmospheric circulations and Arctic Sea ice. The atlas also makes various comparisons among different multi-model ensemble methods in order to obtain the most reliable estimation.
1 online resource (xvi, 247 p.) : ill. (some col.)
"Biofluid mechanics is the study of a certain class of biological problems from the viewpoint of fluid mechanics. Though biofluid mechanics does not involve any new development of the general principles of fluid mechanics, it does involve some new applications of its methods. Complex movements of fluids in the biological system demand for an analysis achievable only with professional fluid mechanics skills, and this volume aims to equip readers with the knowledge needed. This second edition is an enlarged version of the book published in 1992. While retaining the general plan of the first edition, this new edition presents an engineering analysis of the cardiovascular system relevant to the treatment of cardiovascular diseases and combines engineering principles. Included in the material of this volume are: the emerging interdisciplinary field of tissue engineering, which deals with the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain and improve tissue function, and cellular and molecular bioengineering, which involves the mechanical, electrical and chemical processes of the human cell and tries to explain how cellular behaviour arises from molecular-level interactions. The added material in this edition is specifically designed for biomedical engineering professionals and students, and looks at the important applications of biofluid mechanics from an engineering perspective."-- Provided by publisher.
1 online resource
  • Introduction Biologics to Treat Substance Use Disorders: Vaccines, Monoclonal Antibodies, and Enzymes Phil Skolnick Section 1. Vaccines Therapeutic Vaccines for Treating Nicotine Addiction. Matthew W. Kalnik, Ph.D. Vaccines for Treating Cocaine Use Disorders Coreen B. Domingo-- Daryl Shorter-- Thomas R. Kosten Vaccines for Opioid Addiction Michael Raleigh and Paul Pentel Vaccines for Methamphetamine Use Disorder Thomas R. Kosten and Therese A. Kosten Vaccine for Cocaine Addiction and HIV infection Timothy Cardozo, Sergey Shmelkov, Kenneth Ca rr, John Rotrosen, Pedro Mateu-Gelabert, Samuel R. Friedman Section 2. Monoclonal antibodies Monoclonal Antibodies: Introduction S. Michael Owens Anti-cocaine monoclonal antibodies Hanna N. Wetzel, William J. Ball and Andrew B. Norman Discovery and Development of an Anti-methamphetamine Monoclonal Antibody for use in Treating Methamphetamine Abuse Michael D. Hambuchen, Misty W. Stevens, Melinda G. Gunnell, W. Brooks Gen-try, and S. Michael Owens Section 3. Enzymes Enzyme-based cocaine pharmacotherapies: Current status and projections for the future. James H. Woods, Chang-Guo Zhan Viral gene transfer of enzymes W. Steve Brimijoin Cocaine Hydrolases Designed from Butyrylcholinesterase Fang Zheng and Chang-Guo Zhan Section 4. Strategies to optimize the development of biologics to treat addictions Adenovirus-Based Vaccines for the Treatment of Substance Use Disorders David F. Havlicek, Jonathan B. Rosenberg, Dolan Sondhi, Ronald G. Crystal and Stephen M. Kaminsky Nanotechnology based nicotine vaccine Petr O. Ilyinskii and Lloyd P.M. Johnston Exploration of DNA nanostructures for rational design of vaccines Xiaowei Liu, Sidney M. H echt, Hao Yan, Paul R. Pentel, and Yung Chang Adjuvants for Substance Abuse Vaccines Frank M. Orson, Berma M. Kinsey, Muthu Ramakrishnan, Reetakshi Arora, Thomas R. Kosten Skin Vaccination against Nicotine Addiction Xinyuan Chen, Ji Wang, Jeffrey H. Wu, and Mei X. Wu Hapten design for anti-addiction vaccine development Karen C. Collins, Kim D. Janda B cell mechanisms underlying vaccine efficacy against drugs of abuse Marco Pravetoni, Ph.D. Section 5. Practical Considerations Practical considerations for the development of vaccines against drugs of abuse Oscar B. Torres, Carl R. Alving, Arthur E. Jacobson, Kenner C. Rice and Gary R. Matyas Ethical Aspects of Biologics to Treat Substance Use Disorders Ivan D. Montoya.
  • (source: Nielsen Book Data)
This book is a scientific compendium documenting the state of the art in the discovery and development of vaccines, monoclonal antibodies, and enzymes for the treatment of Substance Use Disorders (SUDs). The book gives detailed consideration to some of the most cutting edge topics in addiction medicine, including vaccines for nicotine, cocaine, heroin, and methamphetamine dependence; monoclonal antibodies against cocaine, methamphetamine, and phencyclidine; and the enzymes butyrylcholinesterase and cocaine esterase. In addition, the text covers a wide range of new strategies designed to optimize the development and efficacy of biologics. Unlike any other resource, this book reviews how biologics offer exciting new therapeutic opportunities for various psychiatric conditions. Written by experts in the field, Biologics to Treat Substance Use Disorders is as an authoritative reference for psychiatrists, psychologists, and all other medical professionals working with patients suffering from Substance Use Disorders.
(source: Nielsen Book Data)
1 online resource (1 video file, approximately 115 minutes) : digital, .flv file, sound
This episode picks up the story in the wake of the declaration of a war on cancer by Richard Nixon in 1971. Flush with optimism and awash with federal dollars, the cancer field plunges forward in search of a cure. In the lab, rapid progress is made in understanding the essential nature of the cancer cell, leading to the revolutionary discovery of the genetic basis of cancer. But at the bedside, where patients are treated, few new therapies become available, and a sense of disillusionment takes hold, leading some patients and doctors to take desperate measures. It is not until the late 1990s that the advances in research begin to translate into more precise targeted therapies with the breakthrough drugs Gleevec and Herceptin. Following the history during these fraught decades, the film intertwines the contemporary story of Dr. Lori Wilson, a surgical oncologist who is diagnosed with invasive breast cancer in both breasts in 2013. Her emotional and physical struggles with the disease provide a bracing counterpoint to the historical narrative.
1 online resource (1 video file, approximately 10 minutes) : digital, .flv file, sound
Designing Life. Man has been doing it for over 10,000 years. You may not be aware of it, but we are surrounded by Superlife, life-forms manipulated by Man. Clone Dog: Labrador Retriever, part of the Superlife Series, looks at cloning animals with exceptional capabilities. Note- Superlife explores the science of how mankind is manipulating life for its benefit. The series does not attempt to address the concerns surrounding cloning, genetically modified organisms or the ethics of certain farming practices.
1 online resource : illustrations.
online resource (xxi, 417 pages) : illustrations
  • Part I. Introducing the Domain and Levels of Service
  • 1. Character of domain and organization of book
  • 2. Economy 1: immanent mismatch between demand and supply of health care workforce
  • 3. Level 0: searching-finding-trusting-acting-risking one's life?
  • 4. Level 1: enhancing the provider- client relation through IT
  • 5. Level 2: services without in-person contact between provider and client
  • 6. Level 3: patient power on the web: the multifaceted role of personal health wisdom
  • 7. Distinctive features of services conveyed through mobile apps
  • Part II. Building Safety Nets Around the Active Client
  • 8. Dimensions of patient risks and requirements for patient safety
  • 9. Services for all stages of the metabolic syndrome and its consequences
  • 10. Basic services reach out towards under-served populations
  • 11. Smart homes: empowering the patient till the end
  • 12. Partial solutions for patient safety
  • Part III. Additional Methodology
  • 13. Privacy and data protection: mission impossible?
  • 14. The patient-centered electronic health record and patient portals
  • 15. Scrutinized proof of effectiveness or cost effectiveness regarding patient reported outcomes
  • 16. Economy 2: economic subsistence of services when research funding ends
  • 17. Towards future consumer health informatics adapted health care legislation
  • Trademarks
  • Nomenclature
  • General index
  • Index of services.
Medical Library (Lane)
41 p. ; 21 x 30 cm.
There are now a large number of valuation studies on the benefits of biodiversity and on ecosystem services, the services provided by different ecosystems (ESS). Both ideas have been used to elicit values from nature but in recent years the research community has focussed on ESS as the main organising framework, with some additional use of the biodiversity concept to value entities that have intrinsic value and are of an extraordinary nature. Estimates are available for the services from most habitats, by type of ecosystem service, usually expressed in USD per hectare per year. Coverage varies by habitat and region, as does the quality of the assessment, but it is possible now to carry out an estimation of changes in values for a number of ecosystem services a result of the introduction of a new policy or of a physical investment that modifies the ecosystem. While this is a positive development, there remain some issues to be resolved. One is the possibility of double-counting of services when using the standard categories of provisioning, regulating/supporting and cultural ESS. Regulating and supporting services are the basis of the provisioning services and so value estimates for the two cannot always be added up. For example, air pollution absorption is often valued using the cost of alternative ways of reducing the pollutants from the atmosphere while recreation is often valued in terms of willingness-to-pay (WTP) through stated preference methods.
1 online resource (Article No. e01234-15 ) : digital, PDF file.
<p><italic>Burkholderia mallei</italic>, the etiologic agent of glanders, is a Gram-negative, nonmotile, facultative intracellular pathogen. Though glanders have been eradicated from many parts of the world, the threat of<italic>B. mallei</italic>being used as a weapon is very real. We, then, present draft genome assemblies of 8<italic>Burkholderia mallei</italic>strains that were isolated in Turkey.</p>
1 online resource (XVI, 243 p.) : online resource. Digital: text file; PDF.
  • 1 - Underneath the Pantanal Wetland: a Deep-time History of Gondwana Assembly, Climate Change, and the Dawn of Metazoan Life (LV Warren*, F Quaglio, M G Simoes, BT Freitas, ML Assine and C Ricommini) 2 - Geology and Geomorphology of the Pantanal Basin (ML Assine*, A Silva, FN Pupim, ER Merino and D Mendes) 3 - Paleolimnology in the Pantanal: Using Lake Sediment Archives to Track Late Quaternary Environmental Change in the World's Largest Neotropical Wetland (MM McGlue*, A Silva, ML Assine, JC Stevaux and FW Cruz) 4 - Changing Rivers and the Hydrology of the Pantanal Wetland (ML Assine*, JC Stevaux, HA Macedo, I Bergier, C Padovani, and A Silva) *Corresponding author: "Mario L. Assine" 5 - Terrestrial and Aquatic Vegetation Diversity of the Pantanal Wetland (A Pott* and JSV Silva) 6 - Metabolic Scaling Applied to Native Woody Savanna Species in the Pantanal of Nhecolandia (I Bergier, SM Salis*, and PP Mattos) 7 - Alkaline Lakes Dynamics in the Nhecolandia Landscape (I Bergier*, A Krusche and F Guerin) 8 - Methane and Carbon Dioxide Emissions from the Paraguay River floodplain (Pantanal) during Episodic Anoxia Events (I Bergier*, APS Silva, H Monteiro, F Guerin, HA Macedo, A Silva, A Krusche, HO Sawakuchi and D Bastviken) 9 - Pesticides in the Pantanal (E Dores) 10 - Historical Land-use Changes in Sao Gabriel do Oeste at the Upper Taquari River Basin (LS Buller*, GB Silva, MR Zanetti, E Ortega, A Moraes, T Goulart and I Bergier) 11 - Natural and Environmental Vulnerability along the Touristic "Estradas Parque Pantanal" by GIS Algebraic Mapping (GH Cavazzana, G Lastoria, KF Roche, TGT Catalini and AC Paranhos Filho) 12 - Climate Change Scenarios in the Pantanal (J Marengo*, G Sampaio and LM Alves).
  • (source: Nielsen Book Data)
This book provides readers with in-depth insights into the changes in the Pantanal wetland from its formation to the actual and likely future states. It reveals that today's Pantanal is an evolutionary consequence of geological, ecological and, more recently, man-made events taking place at distinct space-time intervals. Topics include geotectonics and sun-earth interactions, which largely dictate the rate of drastic changes that eventually disrupt ecological stability and radically rebuild the regional landscape. Furthermore, the biota-climate system is discussed as a major driver reshaping the ecohydrology functioning of the landscape on an intermediate timescale. Also covered are major changes in the landscape ecohydrology and biodiversity due to recent land-use and climate changes induced by humankind in the Anthropocene. The ability to recognize how those temporal scales impact the Pantanal wetland provides the opportunity for wise management approaches and the sustainable development of the region.
(source: Nielsen Book Data)
1 online resource (xiv, 220 p.) : ill. (some col.). Digital: text file; PDF.
  • Introduction on emerging contaminants in rivers and their environmental risk.- Contaminants of emerging concern in Mediterranean watersheds.- Emerging organic contaminants in aquifers: Sources, transport, fate, and attenuation.- Effects of emerging contaminants on biodiversity, community structure, and adaptation of river biota.- Bioaccumulation of emerging contaminants in the biota: patterns in Mediterranean river networks.- Ecosystem responses to emerging contaminants: fate and effects of pharmaceuticals in a Mediterranean river.- Fate and degradation of emerging contaminants in rivers: Models review.- The emerging contaminants in the context of the EU Water Framework Directive.
  • (source: Nielsen Book Data)
This volume offers an overview of the occurrence of emerging organic contaminants in Mediterranean rivers and their relevance to their chemical and ecological quality under water scarcity. With chapters covering the effects under multiple stress conditions of pharmaceuticals, polar pesticides, personal care products, and industrial chemicals, the observations presented can be applicable to other parts of the world where water scarcity is an issue . It is of interest to environmental chemists, ecologists, environmental engineers, and ecotoxicologists, as well as water managers and decision-makers.
(source: Nielsen Book Data)
1 online resource (xiv, 263 p.) : ill. (some col.). Digital: text file; PDF.
  • Part I: Solar and Wind Energy Recursive Estimation Methods to Forecast Short-Term Solar Irradiation A. Martin, Juan R. Trapero Technical and environmental analysis of parabolic trough Concentrating Solar Power (CSP) technologies G. San Miguel, B. Corona, J. Servert, D. Lopez, E. Cerrajero, F. Gutierrez, M. Lasheras Wind power forecast error probabilistic model using Markov Chains S. Martin Martinez, A. Honrubia Escribano, M. Canas Carreton, V. Guerrero Mestre and E. Gomez Lazaro Part II: Energy Storage Energy Storage Integration with Renewable Energies: the Case of Concentration Photovoltaic Systems Carlos de la Cruz, Monica Baptista Lema, Xavier del Toro Garcia, Pedro Roncero-Sanchez Batteries and Ultracapacitors based Energy Storage in Renewable Multi-Sources Systems Mahamadou Abdou Tankari, Gilles Lefebvre Different Phase Change Materials Implementations for Thermal Energy Storage Mustapha Karkri, Gilles Lefebvre, Laurent Royon Part III: Biomass Bio-refineries: an Overview on Bio-Ethanol Production Juan Carlos Dominguez Toribio, Francisco Jesus Fernandez Morales Effects of External Resistance on Microbial Fuel Cell's Performance A. Gonzalez del Campo, P. Canizares, J. Lobatob, M. Rodrigo, F.J. Fernandez The avocado and its waste: an approach of fuel potential/application Maria Paz Dominguez-- Karina Araus-- Pamela Bonert-- Francisco Sanchez-- Guillermo San Miguel-- Mario Toledo Part IV: Socio-economy of Energy Agency and Learning Relationships Against Energy Efficiency Barriers Martin Rubio, I., Florence Sandoval, A., Gonzalez Sanchez, E.
  • (source: Nielsen Book Data)
This volume provides a comprehensive overview of advanced research in the field of efficient, clean and renewable energy production, conversion and storage. The ten chapters, written by internationally respected experts, address the following topics: (1) solar and wind energy; (2) energy storage in batteries; (3) biomass; and (4) socio-economic aspects of energy. Given its multidisciplinary approach, which combines environmental analysis and an engineering perspective, the book offers a valuable resource for all researchers and students interested in environmentally sustainable energy production, conversion, storage and its engineering.
(source: Nielsen Book Data)
54 p. ; 21 x 30 cm.
This paper examines the relationship between environmental policy and "green" innovation in shipbuilding. The primary motivating question of this work is whether there is evidence of: i) technology push from innovation that enables environmental policy initiatives; and/or, ii) policy pull that induces innovation leading to "green" ships. This paper focuses on four environmental categories of technological innovation in the shipbuilding industry, encompassing oil spill recovery, emissions control, climate change mitigation and ballast water treatment. The analysis draws upon documents filed at the International Maritime Organization (IMO) to proxy for policy measures, and uses patent data of the Worldwide Statistical Patent Database, maintained by the European Patent Office (EPO), to account for innovation. Our results show a similar trend between patent activity and IMO document submissions over the years 1998 to 2012 for the two environmental categories, climate change mitigation and emissions control. The key contribution of this work are to provide more insights into environmental policy in shipbuilding and its role in innovation activity, as well as to develop a rich dataset focused on IMO policies aimed at encouraging improved environmental performance by ships.
38 p. ; 21 x 30 cm.
This paper explores the relationship between environmental regulation, innovation, and competitiveness, drawing upon a unique dataset on environmental regulations directed at combustion plants, a global dataset of power plants, and a global dataset of ‘environmental’ patents. The analysis is conducted in two stages. First, a nonparametric frontier analysis is implemented to estimate efficiency scores, including a measure of technological innovation based on patent stocks. Second, econometric methods are applied to analyse the role of policy stringency and policy design on efficiency. Our estimation sample covers thermal power plant sectors in 20 countries from 1990 to 2009. The results show that the stringency of environmental regulations is a significant determinant of productive efficiency with respect to pollutant emissions as well as fuel use. However, these effects turn negative once the level of stringency leaps over a certain threshold. In addition, the paper concludes that the positive effect of regulatory stringency can be diminished by a negative effect of regulatory differentiation with measures which are differentiated across plant size and age having negative consequences, and these effects are increasing over time. This finding is important given the prevalence of size- and vintage-differentiated policies in many countries. Finally, it is found that integrated approaches to environmental innovation are more likely to bring about efficiency improvements than end-of-pipe technologies.
37 p. ; 21 x 30 cm.
This paper presents the first empirical analysis of the macroeconomic relationship between environmentally related taxes and inequality in income sources. The analysis also investigates whether this relationship differs between countries which have implemented environmental tax reforms (ETRs) and ones which have not. Following earlier empirical literature, income inequality is measured by the disposable-income-based Gini coefficient. The analysis is based on a panel of all 34 OECD countries spanning the period from 1995 to 2011. Information about the implementation of ETRS in the examined period is collected through a review of relevant academic and policy literature. Empirical results from econometric models reveal that, on average, there is no statistically significant relationship between the overall share of environmentally related tax revenues in GDP and inequality in income sources. However, the relationship varies with the taxed activity under consideration and the existence of an explicit mechanism to redistribute environmentally related tax revenues. In countries where such mechanisms are absent, energy tax revenues (% of GDP) are shown to have a positive, although modest, relationship with income inequality. In contrast, in countries where energy tax revenues are, at least partially, used to reduce tax burden on income and labour, there is a negative relationship between energy taxes and inequality in income sources. On the contrary, no significant relationship is identified between motor vehicle and other transport tax revenues and income inequality, while revenues from other environmentally related taxes, such as waste and air pollution taxes, are negatively associated with income inequality, regardless of the existence of an explicit revenue recycling mechanism.
141 p. ; 21x28 cm.
  • Foreword
  • Executive summary
  • Investigating farm management practices that may foster green growth
  • The role of soil and water conservation in the transition to green growth
  • What does organic farming mean for green growth?
  • Unleashing the green growth potential of integrated pest management
  • How critical is modern agricultural biotechnology in increasing productivity sustainably?
  • Is precision agriculture the start of a new revolution?.
This report looks at farm management practices with green growth potential, from farmer-led innovations (such as those directly linked to soil and water, Integrated Pest Management, organic farming) to science-led technologies (such as biotechnology and precision agriculture). Global food demand can only be met in a sustainable way if new forms of agricultural production and innovative technologies can be unlocked to increase the productivity, stability, and resilience of production systems with goals beyond just raising yields, including saving water and energy, reducing risk, improving product quality, protecting the environment and climate change mitigation.
1 online resource (1 video file, approximately 116 minutes) : digital, .flv file, sound
This episode picks up the story at another moment of buoyant optimism in the cancer world: Scientists believe they have cracked the essential mystery of the malignant cell and the first targeted therapies have been developed, with the promise of many more to follow. But very quickly cancer reveals new layers of complexity and a formidable array of unforeseen defenses. In the disappointment that follows, many call for a new focus on prevention and early detection as the most promising fronts in the war on cancer. But other scientists are undeterred, and by the second decade of the 2000s their work pays off. The bewildering complexity of the cancer cell, so recently considered unassailable, yields to a more ordered picture, revealing new vulnerabilities and avenues of attack. Perhaps most exciting of all is the prospect of harnessing the human immune system to defeat cancer. This episode includes patients Doug Rogers, a 60-year-old NASCAR mechanic with melanoma, and Emily Whitehead, a six-year-old child afflicted with leukemia. Each is a pioneer in new immunotherapy treatments, which the documentary follows as their stories unfold. Both see their advanced cancers recede and are able to resume normal lives.