1 PDF (xv, 135 pages).
  • 1. Introduction
  • 1.1 Enabling technologies
  • 1.1.1 Camera-based systems
  • 1.1.2 Body worn sensors
  • 1.1.3 Force and pressure-based systems
  • 1.2 Body tracking in context
  • 1.3 Overview
  • 2. Clinical assessment of motor disability
  • 2.1 Introduction
  • 2.2 Tracking disease progression in multiple sclerosis assessment
  • 2.2.1 Contexts and practices in MS assessment with the EDSS
  • 2.2.2 Challenges and characteristics of assessment room
  • 2.2.3 Doctor-patient relationship in assessment
  • 2.2.4 Summary
  • 2.3 Understanding concerns in system design: assess MS system
  • 2.3.1 System overview
  • 2.3.2 Algorithms
  • 2.3.3 Movement exercise protocol
  • 2.3.4 Ensuring standardized movement performance
  • 2.3.5 Framing and standardization, seeing how the machine sees
  • 2.3.6 Representing the movement measure and classification
  • 2.4 Conclusions
  • 3. Self-directed rehabilitation and care
  • 3.1 Introduction
  • 3.2 Facilitating physical activity in chronic musculoskeletal pain
  • 3.3 Technology for chronic pain rehabilitation
  • 3.3.1 Go-with-the-flow: sonification in movement rehabilitation
  • 3.3.2 Transferring to everyday functioning: kinect vs. wearable smartphone as a body-tracking device
  • 3.3.3 Self-directed rehabilitation as process: from clinical facilitation to self-management
  • 3.3.4 Tracking affective states and pain levels
  • 3.4 Exergaming and balance rehabilitation in older adults
  • 3.4.1 Balance and fall risk in older adults
  • 3.4.2 Body-tracking technology for balance training
  • 3.4.3 Designing a balance training game
  • 3.4.4 Understanding rehabilitative game use
  • 3.5 Conclusion
  • 4. Interactions for clinicians
  • 4.1 Introduction
  • 4.2 Sterility and constraints on imaging practices
  • 4.3 Tracking the body of the clinician for enabling touchless interaction with images
  • 4.4 Clinical considerations in gesture design
  • 4.4.1 Clinical constraints on movement in gesture design
  • 4.4.2 Supporting collaboration and control
  • 4.4.3 What actions and body parts to track for the purposes of system control
  • 4.4.4 Engaging and disengaging the system
  • 4.4.5 Feedback and making oneself sensed
  • 4.4.6 Coarse vs. fine-grained control
  • 4.5 Body tracking, gesture, and robotics
  • 4.6 Increasing interaction bandwidth through input modality
  • 4.7 Conclusions
  • 5. Conclusions
  • 5.1 Introduction
  • 5.2 Contextual design
  • 5.2.1 Sensor technology
  • 5.2.2 Data and algorithms
  • 5.2.3 Designing movements
  • 5.2.4 Interface and interaction design
  • 5.2.5 Physical set-up and form factor
  • 5.2.6 Social set-up and practices
  • 5.3 The future
  • Bibliography
  • Author biographies.
Within the context of healthcare, there has been a long-standing interest in understanding the posture and movement of the human body. Gait analysis work over the years has looked to articulate the patterns and parameters of this movement both for a normal healthy body and in a range of movement-based disorders. In recent years, these efforts to understand the moving body have been transformed by significant advances in sensing technologies and computational analysis techniques all offering new ways for the moving body to be tracked, measured, and interpreted. While much of this work has been largely research focused, as the field matures, we are seeing more shifts into clinical practice. As a consequence, there is an increasing need to understand these sensing technologies over and above the specific capabilities to track, measure, and infer patterns of movement in themselves. Rather, there is an imperative to understand how the material form of these technologies enables them also to be situated in everyday healthcare contexts and practices. There are significant mutually interdependent ties between the fundamental characteristics and assumptions of these technologies and the configurations of everyday collaborative practices that are possible them. Our attention then must look to social, clinical, and technical relations pertaining to these various body technologies that may play out in particular ways across a range of different healthcare contexts and stakeholders. Our aim in this book is to explore these issues with key examples illustrating how social contexts of use relate to the properties and assumptions bound up in particular choices of body-tracking technology. We do this through a focus on three core application areas in healthcare-assessment, rehabilitation, and surgical interaction-and recent efforts to apply body-tracking technologies to them.
(source: Nielsen Book Data)9781627054560 20160619
1 online resource (1 streaming video file (36 min.) : color, sound).
  • Contents: Cardiac aging in human and animal models
  • Molecular mechanisms for cardiac aging
  • Recent advances on potential interventions for cardiac aging
  • Future perspectives of cardiac aging interventions.
online resource (x, 438 pages) : color illustrations ; 19 cm
  • Fundamentals / S. Silbernagl and F. Lang
  • Temperature, energy / S. Silbernagl
  • Blood / S. Silbernagl
  • Kidney, salt and water balance / F. Lang
  • Stomach, intestines, liver / S. Silbernagl
  • Heart and circulation / S. Silbernagl
  • Metabolic disorders / S. Silbernagl
  • Hormones / F. Lang
  • Neuromuscular and sensory systems / F. Lang.
Medical Library (Lane)
1 online resource (284 ill., 186 illus. in color. eReference.) : online resource. Digital: text file; PDF.
  • â General aspects, definitions and assessments of PTSD.- PTSD in different conditions, groups, and specific incidents.- PTSD in relation to psychotic conditions or assessments.- Peritraumatic stress.- Biochemical, molecular, and genetic aspects of PTSD.- Neurological and neurogenic aspects of PTSD.- PTSD as a risk factor in causation of diseases and pathology.- PTSD in children and adolescents.- Animal models of PTSD: enhancing understanding.- PTSD in international and comparative perspective.- PTSD and selective conditions of stress and anxiety.- Treatments and therapies of PTSD.
  • (source: Nielsen Book Data)9783319083599 20160912
This is an all-embracing reference that offers analyses and discussions of contemporary issues in the field of PTSD. The book brings together scientific material from leading experts in the field relating to a wide range of important current topics across disciplines. These include the early identification of PTSD and subsequent treatment, to social and behavioral studies, to biochemical, molecular and genetic research. With more than 125 chapters organized in 12 major sections, this is the most complete single resource on PTSD.
(source: Nielsen Book Data)9783319083599 20160912
1 online resource (1 streaming video file (48 min.) : color, sound).
  • Contents: Insights into human aging
  • The compression of morbidity: central thesis
  • Reduction in health risks postpones aging
  • Delay aging by lifelong exercise
  • Exercise and morbidity
  • Actions that postpone aging
  • Multiple controlled longitudinal studies.
1 online resource (1 streaming video file (31 min.) : color, sound).
  • Contents: Developmental plasticity
  • Genes and environment in development
  • Adaptive developmental decisions and their betrayal if conditions change
  • Phenotypic accommodation
  • Multiple pathways
  • Myth of single gene control
  • Blueprints and programs as false metaphors
  • Cross-generational continuity of the phenotype
  • Origins of novel phenotypes including disease.
1 online resource : illustrations (chiefly color)
  • * Anatomy of the eye and orbit. * Embryology and early development of the eye and adnexia. * Genetics. * Biochemistry and cell biology. * Physiology of vision and the visual system. * General and ocular pharmacology. * Immunology. * Microbiology and infection. * Pathology.* Index.
  • (source: Nielsen Book Data)9780702055546 20160618
The Eye: Basic Sciences in Practice provides highly accessible, concise coverage of all the essential basic science required by today's ophthalmologists and optometrists in training. It is also essential reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area. This new fourth edition has now been fully revised and updated in line with current curricula, key research developments and clinical best practice. It succinctly incorporates the massive strides being made by genetics and functional genomics based on the Human Genome Project, the new understanding of how the microbiome affects all aspects of immunology, the remarkable progress in imaging technology now applied to anatomy and neurophysiology, as well as exciting new molecular and other diagnostic methodologies now being used in microbiology and pathology. All this and more collectively brings a wealth of new knowledge to students and practitioners in the fields of ophthalmology and visual science. For the first time, this (print) edition also now comes with bonus access to the complete, fully searchable electronic text - including carefully selected additional information and new video content to further explain and expand on key concepts - making The Eye a more flexible, comprehensive and engaging learning package than ever before.
(source: Nielsen Book Data)9780702055546 20160618
1 online resource (XIII, 115 p. 30 ill., 17 illus. in color.) : online resource. Digital: text file; PDF.
  • Introduction to NeuroIS.- A Primer on Neurobiology and the Brain for Information Systems Scholars.- Tools in NeuroIS Research: An Overview.- Topics in NeuroIS and a Taxonomy of Neuroscience Theories in NeuroIS.- quot--Times New Roman"--mso-ansi-language:EN-CA--mso-fareast-language:DE--mso-bi di-language: AR-SA">Establishing and Operating a NeuroIS Lab.
  • (source: Nielsen Book Data)9783662450901 20160619
This authored volume presents the fundamentals of NeuroIS, which is an emerging subfield within the Information Systems discipline that makes use of neuroscience and neurophysiological tools and knowledge to better understand the development, use, and impact of information and communication technologies. This book is an initial guide to this new research domain. The target audience primarily comprises PhD students and researchers, but the book may also be beneficial for graduate students and practitioners.
(source: Nielsen Book Data)9783662450901 20160619
1 online resource (1 streaming video file (40 min.) : color, sound).
  • Contents: Complexity of the lung cancer genome
  • Molecular classification of subtypes
  • Pathways of activation in tumors
  • Intratumoral heterogeneity
  • Targetable alterations in patients
  • Emerging areas in genomics of lung cancer.
1 online resource (1 streaming video file (45 min.) : color, sound).
  • Contents: Life phases and human senescent phenotypes
  • Seven major human senescence phenotypes
  • Hypertension
  • Atherosclerosis
  • Alzheimer's disease
  • Diabetes type 2
  • Muscle aging
  • Gastrointestinal cancers
  • Skin aging
  • Inflammasomes and aging.
1 online resource (viii, 333 p.) Digital: text file; PDF.
  • The Mechanophysiololgy of Stress Fractures in Military Recruits.- Traumatic Brain Injury in the Military: Biomechanics and Finite Element Modelling.- Modeling Skeletal Injuries in Military Scenarios.- Biomechanics of Eye Injury in the Military.- The Biomechanical Basis for Increased Risk of Overuse Musculoskeletal Injuries in Female Soldiers.
  • (source: Nielsen Book Data)9783319330105 20160619
This book provides a state-of-the-art update, as well as perspectives on future directions of research and clinical applications in the implementation of biomechanical and biophysical experimental, theoretical and computational models which are relevant to military medicine. Such experimental and modeling efforts are helpful, on the one hand, in understanding the aetiology, pathophysiology and dynamics of injury development and on the other hand in guiding the development of better equipment and protective gear or devices that should ultimately reduce the prevalence and incidence of injuries or lessen their hazardous effects. The book is useful for military-oriented biomedical engineers and medical physicists, as well as for military physiologists and other medical specialists who are interested in the science and technology implemented in modern investigations of military related injuries.
(source: Nielsen Book Data)9783319330105 20160619
1 online resource ()
  • Front Cover; Molecular Basis of Nutrition and Aging; Copyright Page; Contents; List of Contributors; Introduction to the Molecular Basis of Nutrition and Aging; Series Preface; Acknowledgments; I. Introductory Aspects on Aging and Nutrition; 1 Molecular and Cellular Basis of Aging; Introduction; Biological Principles of Aging; Occurrence, Accumulation, and Consequences of Molecular Damage; Homeodynamics and the Homeodynamic Space; Nutrition and Food for Aging Interventions; Nutritional Hormetins; Conclusions; Summary Points; References.
  • 2 Unraveling Stochastic Aging Processes in Mouse Liver: Dissecting Biological from Chronological AgeIntroduction; Pathological Parameters are only Partially Associated with Chronological Age; Intraorgan Specific Biological Phenotypes; Tissue-Specific Biological Phenotypes; Gene Expression Profiles Related to Pathological Aging Parameters; Gene Expression Profiles Correlating with Pathological Parameters are Largely Specific to the Pathological Parameters; Future Perspectives; Conclusion; References; 3 Nutrigenomics and Nutrigenetics: The Basis of Molecular Nutrition; Introduction.
  • Nutrigenetics of Omega-3 PUFA in CVDNutrigenetics of Omega-3 PUHA in Cancer; DNA Damage and Nutrients; Cellular Senescence and Nutrients; Epigenetics and Nutrients; Summary Points; References; 4 Diet and Longevity Phenotype; Introduction; Main Text; Nutrient Components and Aging Process; Crucial Role of Fatty Acid Component; Genomic Studies and Importance of Palmitoleic Acid; The Central Position of Energy Sensor Systems; The Involvement of Sympathetic System; Epigenetic Linkage of Aging and Nutrition; Summary; References; 5 Nutrition in the Elderly: General Aspects; Introduction.
  • Malnutrition in the Elderly: Definition and General AspectsCauses of Malnutrition in the Elderly; Malnutrition: Possible Correction With Supplements in the Elderly; Nutrient-Sensing Pathways; Nutrient-Gene Interaction in the Elderly (Nutrigenomic Approach); Conclusions and Perspectives; Summary Points; Acknowledgments; References; 6 Nutrition in the Hospitalized Elderly; Introduction; Pathogenesis of Malnutrition in Hospitalized Elderly; The Interaction Between Aging, Health Status, Hospital Environment, and Nutritional Status; Why Are Hospitalized Older Adults Nutritionally Vulnerable?
  • Age-Related ChangesAnorexia of Aging; Changes in the Body Composition; Taste, Smell, and Mastication Dysfunction; Gastrointestinal Changes; Medical Causes; Use of Multiple Medications; Functional and Psychosocial Factors; Hospital Environment-Related Risks; Clinical Consequences of Malnutrition in Hospital; Malnutrition Screening and Assessment in Hospitalized Elderly; Malnutrition Screening as a Part from Comprehensive Geriatric Assessment (CGA); Comprehensive Nutritional Assessment; Nutritional History; Physical and Clinical Assessment; Anthropometry; The Biochemical Investigations.
1 online resource (1 streaming video file (39 min.) : color, sound).
  • Contents: Neuropathology of amyotrophic lateral sclerosis (ALS)
  • Neuroinflammation in human ALS
  • Neuroinflammation in ALS mouse model
  • Role of microglia in ALS
  • Role of T cells in ALS
  • TREM2
  • Progranulin.
1 online resource (392 p.)
  • Introduction: a new perspective on the epidemiology of physical activity.- Chapter 1. Physical activity and optimal health: the challenge to epidemiology.- Chapter 2. History of physical activity measurement in epidemiology.- Chapter 3. Evolution of the pedometer.- Chapter 4. Newer approaches to the objective measurement of physical activity.- Chapter 5. Optimal patterns for the sampling of physical activity in various age groups and environments.- Chapter 6. New information on population activity patterns revealed by objective monitoring.- Chapter 7. Can the epidemiologist learn more from sedentary behaviour than from the measurement of physical activity?.- Chapter 8. New perspectives on activity/disease relationships yielded by objective monitoring.- Chapter 9. Excessive appetite vs. inadequate physical activity in the pathology of obesity. Evidence from objective monitoring.- Chapter 10. Objective monitoring and the challenge of defining dose/response relationships for the prevention of chronic disease.- Chapter 11. The economic benefits of increased physical activity as seen through an objective lens.- Chapter 12. Limitations of current objective monitors and the potential to overcome these problems.- Chapter 13. Future directions and conclusions.
  • (source: Nielsen Book Data)9783319295756 20161010
This book examines the new knowledge that has been gained from the objective monitoring of habitual physical activity by means of pedometers and accelerometers. It reviews current advances in the technology of activity monitoring and details advantages of objective monitors relative to physical activity questionnaires. It points to continuing gaps in knowledge, and explores the potential for further advances in the design of objective monitoring devices. Epidemiologists have studied relationships between questionnaire assessments of habitual physical activity and various medical conditions for some seventy years. In general, they have observed positive associations between regular exercise and good health, but because of inherent limitations in the reliability and accuracy of physical activity questionnaires, optimal exercise recommendations for the prevention and treatment of disease have remained unclear. Inexpensive pedometers and accelerometers now offer the epidemiologist the potential to collect relatively precisely graded and objective information on the volume, intensity and patterns of effort that people are undertaking, to relate this data to past and future health experience, and to establish dose/response relationships between physical activity and the various components of health. Such information is important both in assessing the causal nature of the observed associations and in establishing evidence-based recommendations concerning the minimal levels of daily physical activity needed to maintain good health.
(source: Nielsen Book Data)9783319295756 20161010
1 online resource.
  • 1- Models for studying Organogenetic gene networks in the 21st century James Castelli-Gair Hombria and Paola Bovolenta 2- Organogenesis of the C. elegans vulva and control of cell fusion Nathan Weinstein and Benjamin Podbilewicz 3- Advances in understanding the generation and specification of unique neuronal sub-types from Drosophila neuropeptidergic neurons Stefan Thor and Douglas W. Allan 4- Fast and Furious 800. The retinal determination gene network in Drosophila. Fernando Casares and Isabel Almudi 5- Genetic control of salivary gland tubulogenesis in Drosophila Clara Sidor and Katja Roper 6- Organogenesis of the Drosophila respiratory system Rajprasad Loganathan, Yim Ling Cheng, Deborah J. Andrew 7- Organogenesis of the zebrafish kidney George Chang, Richard W. Naylor, and Alan J. Davidson 8- Morphogenetic mechanisms of inner ear development Berta Alsinaand Andrea Streit 9- Vertebrate eye gene regulatory networks Juan R. Martinez-Morales 10- Vertebrate eye evolution Juan R. Martinez-Morales and Annamaria Locascio 11- Principles of early vertebrate forebrain formation Florencia Cavodeassi, Tania Moreno-Marmol, Maria Hernandez-Bejarano and Paola Bovolenta 12- Control of organoganesis by Hox genes James Castelli-Gair Hombria, Carlos Sanchez-Higeras and Ernesto Sanchez-Herrero Index.
  • (source: Nielsen Book Data)9783319427652 20161010
All animals, including humans, derive from a single cell, which possesses all the genetic instructions needed to define how the animal will look like. However, during development, the millions of cells that derive from the zygote will only select part of this genetic information to give rise to the various organs of the body. The coordination of different cell behaviours during development results in the formation of specialized tissues and organs giving rise to highly adapted animals. This book provides an overview of how this diversification is achieved during organ formation and how it may have evolved. Conserved cellular processes are presented using examples from selected vertebrate and invertebrate species that illustrate how developmental biologists are solving the complex puzzle of organ formation. This volume is aimed to students, researchers and medical doctors alike who want to find a simple but rigorous introduction on how gene networks control organ formation."div>.
(source: Nielsen Book Data)9783319427652 20161010
1 online resource (XIV, 167 p. 71 ill., 27 illus. in color.) : online resource. Digital: text file; PDF.
  • Cell structure and biochemical reactions.- Cellular homeostasis and membrane potential.- The action potential.- Transport and cell-cell transmission.- Pharmacokinetics.- Skeletal-Muscular System.- Cardiovascular system I: The heart.- Cardiovascular system II: The vasculature.- Respiratory system.- Nervous system.
  • (source: Nielsen Book Data)9783319261959 20160619
This book provides an introduction to qualitative and quantitative aspects of human physiology. It looks at biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, including electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text there are introductions to measuring and quantifying physiological processes using both signal and imaging technologies. Physiology for Engineers describes the basic structure and models of cellular systems, the structure and function of the cardiovascular system, the electrical and mechanical activity of the heart and provides an overview of the structure and function of the respiratory and nervous systems. It also includes an introduction to the basic concepts and applications of reaction kinetics, pharmacokinetic modelling and tracer kinetics. It is of interest to final year biomedical engineering undergraduates and graduate students alike, as well as to practising engineers new to the fields of bioengineering or medical physics.
(source: Nielsen Book Data)9783319261959 20160619
1 online resource.
  • Maturation and Physiology of Hypothalamic Regulation of Gonadal Axis.- Genetic Basis of Puberty.- Hormonal Changes in Childhood and Puberty.- Physical Changes in Puberty.- Growth in Childhood and Puberty.- Bone Development in Children and Adolescents.- Body Weight and Puberty.- The environmental factors and epigenetics of gametogenesis in puberty.- Timing of Puberty and Secular Trend in Human Maturation.- Precocious Puberty.- Constitutional Delayed Puberty.- Pubertal Dysfunction - A Disorder of GnRH Pulsatility.- Pubertal Gynecomastia.-Pubertal Acne.- Adolescent Varicocele.- Polycystic Ovary Syndrome in Adolescent Girls.- Growth Hormone and Steroid Assays' Problems in Childhood and Puberty.- Psychosocial Development of Adolescents with and without Deviations.- Substance use in adolescence.
  • (source: Nielsen Book Data)9783319321202 20161010
Bringing together the latest knowledge on the growth and development of children and the most important abnormalities of puberty, this comprehensive text presents the current views on the pathogenesis, diagnostic possibilities and therapeutic options of the main deviations from the normal course of puberty (e.g., precocious and delayed puberty). The chain of physical and hormonal changes in the transitional years is carefully followed, including the regulation of the hypothalamic pulse generator as well as the timing of puberty. Further topics include growth disturbances, adolescent varicocele, adolescent gynecomastia, polycystic ovary syndrome, pubertal acne, and the psychosocial development of adolescents with pubertal abnormalities. Written and edited by internationally noted experts, Puberty will be an excellent resource for pediatricians, endocrinologists, gynecologists, andrologists, urologists, family practitioners, child psychologists and public health specialists - all those who will be challenged in their everyday practice with the problems of puberty.
(source: Nielsen Book Data)9783319321202 20161010
1 online resource.
  • Front Cover; Salience Network of the Human Brain; Copyright Page; Dedication; Contents; List of Figures; Acknowledgment; 1 What Is Salience?; References; 2 Anatomy of the Salience Network; References; 3 Functions of the Salience Network; References; 4 Salience Network Across the Life Span; References; 5 Salience Network Dysfunction; References; 6 Future Directions in Salience Network Research; References; Index; Back Cover
Salience Network of the Human Brain focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience-importance or prominence-of each of these inputs determines which ones we choose to focus on for more in-depth processing. The salience network is a collection of regions of the brain that select which stimuli are deserving of our attention. The network has key nodes in the insular cortex and is critical for detecting behaviorally relevant stimuli and for coordinating the brain's neural resources in response to these stimuli. The insular cortex is a complex and multipurpose structure that plays a role in numerous cognitive functions related to perception, emotion, and interpersonal experience-and the failure of this network to function properly can lead to numerous neuropsychiatric disorders, including autism spectrum disorder, psychosis, and dementia. * Presents the only publication available that summarizes our understanding of the salience network in one resource* Authored by a leading research on this important aspect of attention* Focuses on the multiple sources of stimuli that compete for our attention, providing interesting discussions on how the relative salience-importance or prominence-of each of these inputs determines which ones we choose to focus on for more in-depth processing.
(source: Nielsen Book Data)9780128045930 20161010
1 online resource (XXII, 827 p. 266 ill., 188 illus. in color.) : online resource. Digital: text file; PDF.
Scholarpedia's Encyclopedia of Touch provides a comprehensive collection of peer-reviewed articles written by leading researchers, detailing our current scientific understanding of tactile sensing and its neural substrates in animals including humans. The encyclopedia allows ideas and insights to be shared between researchers working on different aspects of touch and in different species, including research in synthetic touch systems. In addition, this encyclopedia raises awareness of research in tactile sensing and increases scientific and public interest in the field. The articles address subjects including tactile control, whiskered robots, vibrissal coding, the molecular basis of touch, invertebrate mechanoreception, fingertip transducers and tactile sensing. All the articles in this encyclopedia provide in-depth and state-of-the-art scholarly treatment of the academic topics concerned, making it an excellent reference work for academics, professionals and students.
(source: Nielsen Book Data)9789462391321 20160619