1 PDF (xv, 135 pages).
  • 1. Introduction
  • 1.1 Enabling technologies
  • 1.1.1 Camera-based systems
  • 1.1.2 Body worn sensors
  • 1.1.3 Force and pressure-based systems
  • 1.2 Body tracking in context
  • 1.3 Overview
  • 2. Clinical assessment of motor disability
  • 2.1 Introduction
  • 2.2 Tracking disease progression in multiple sclerosis assessment
  • 2.2.1 Contexts and practices in MS assessment with the EDSS
  • 2.2.2 Challenges and characteristics of assessment room
  • 2.2.3 Doctor-patient relationship in assessment
  • 2.2.4 Summary
  • 2.3 Understanding concerns in system design: assess MS system
  • 2.3.1 System overview
  • 2.3.2 Algorithms
  • 2.3.3 Movement exercise protocol
  • 2.3.4 Ensuring standardized movement performance
  • 2.3.5 Framing and standardization, seeing how the machine sees
  • 2.3.6 Representing the movement measure and classification
  • 2.4 Conclusions
  • 3. Self-directed rehabilitation and care
  • 3.1 Introduction
  • 3.2 Facilitating physical activity in chronic musculoskeletal pain
  • 3.3 Technology for chronic pain rehabilitation
  • 3.3.1 Go-with-the-flow: sonification in movement rehabilitation
  • 3.3.2 Transferring to everyday functioning: kinect vs. wearable smartphone as a body-tracking device
  • 3.3.3 Self-directed rehabilitation as process: from clinical facilitation to self-management
  • 3.3.4 Tracking affective states and pain levels
  • 3.4 Exergaming and balance rehabilitation in older adults
  • 3.4.1 Balance and fall risk in older adults
  • 3.4.2 Body-tracking technology for balance training
  • 3.4.3 Designing a balance training game
  • 3.4.4 Understanding rehabilitative game use
  • 3.5 Conclusion
  • 4. Interactions for clinicians
  • 4.1 Introduction
  • 4.2 Sterility and constraints on imaging practices
  • 4.3 Tracking the body of the clinician for enabling touchless interaction with images
  • 4.4 Clinical considerations in gesture design
  • 4.4.1 Clinical constraints on movement in gesture design
  • 4.4.2 Supporting collaboration and control
  • 4.4.3 What actions and body parts to track for the purposes of system control
  • 4.4.4 Engaging and disengaging the system
  • 4.4.5 Feedback and making oneself sensed
  • 4.4.6 Coarse vs. fine-grained control
  • 4.5 Body tracking, gesture, and robotics
  • 4.6 Increasing interaction bandwidth through input modality
  • 4.7 Conclusions
  • 5. Conclusions
  • 5.1 Introduction
  • 5.2 Contextual design
  • 5.2.1 Sensor technology
  • 5.2.2 Data and algorithms
  • 5.2.3 Designing movements
  • 5.2.4 Interface and interaction design
  • 5.2.5 Physical set-up and form factor
  • 5.2.6 Social set-up and practices
  • 5.3 The future
  • Bibliography
  • Author biographies.
Within the context of healthcare, there has been a long-standing interest in understanding the posture and movement of the human body. Gait analysis work over the years has looked to articulate the patterns and parameters of this movement both for a normal healthy body and in a range of movement-based disorders. In recent years, these efforts to understand the moving body have been transformed by significant advances in sensing technologies and computational analysis techniques all offering new ways for the moving body to be tracked, measured, and interpreted. While much of this work has been largely research focused, as the field matures, we are seeing more shifts into clinical practice. As a consequence, there is an increasing need to understand these sensing technologies over and above the specific capabilities to track, measure, and infer patterns of movement in themselves. Rather, there is an imperative to understand how the material form of these technologies enables them also to be situated in everyday healthcare contexts and practices. There are significant mutually interdependent ties between the fundamental characteristics and assumptions of these technologies and the configurations of everyday collaborative practices that are possible them. Our attention then must look to social, clinical, and technical relations pertaining to these various body technologies that may play out in particular ways across a range of different healthcare contexts and stakeholders. Our aim in this book is to explore these issues with key examples illustrating how social contexts of use relate to the properties and assumptions bound up in particular choices of body-tracking technology. We do this through a focus on three core application areas in healthcare-assessment, rehabilitation, and surgical interaction-and recent efforts to apply body-tracking technologies to them.
(source: Nielsen Book Data)9781627054560 20160619
1 online resource : illustrations (chiefly color)
  • * Anatomy of the eye and orbit. * Embryology and early development of the eye and adnexia. * Genetics. * Biochemistry and cell biology. * Physiology of vision and the visual system. * General and ocular pharmacology. * Immunology. * Microbiology and infection. * Pathology.* Index.
  • (source: Nielsen Book Data)9780702055546 20160618
The Eye: Basic Sciences in Practice provides highly accessible, concise coverage of all the essential basic science required by today's ophthalmologists and optometrists in training. It is also essential reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area. This new fourth edition has now been fully revised and updated in line with current curricula, key research developments and clinical best practice. It succinctly incorporates the massive strides being made by genetics and functional genomics based on the Human Genome Project, the new understanding of how the microbiome affects all aspects of immunology, the remarkable progress in imaging technology now applied to anatomy and neurophysiology, as well as exciting new molecular and other diagnostic methodologies now being used in microbiology and pathology. All this and more collectively brings a wealth of new knowledge to students and practitioners in the fields of ophthalmology and visual science. For the first time, this (print) edition also now comes with bonus access to the complete, fully searchable electronic text - including carefully selected additional information and new video content to further explain and expand on key concepts - making The Eye a more flexible, comprehensive and engaging learning package than ever before.
(source: Nielsen Book Data)9780702055546 20160618
1 online resource (XIII, 115 p. 30 ill., 17 illus. in color.) : online resource. Digital: text file; PDF.
  • Introduction to NeuroIS.- A Primer on Neurobiology and the Brain for Information Systems Scholars.- Tools in NeuroIS Research: An Overview.- Topics in NeuroIS and a Taxonomy of Neuroscience Theories in NeuroIS.- quot--Times New Roman"--mso-ansi-language:EN-CA--mso-fareast-language:DE--mso-bi di-language: AR-SA">Establishing and Operating a NeuroIS Lab.
  • (source: Nielsen Book Data)9783662450901 20160619
This authored volume presents the fundamentals of NeuroIS, which is an emerging subfield within the Information Systems discipline that makes use of neuroscience and neurophysiological tools and knowledge to better understand the development, use, and impact of information and communication technologies. This book is an initial guide to this new research domain. The target audience primarily comprises PhD students and researchers, but the book may also be beneficial for graduate students and practitioners.
(source: Nielsen Book Data)9783662450901 20160619
1 online resource (1 streaming video file (40 min.) : color, sound).
  • Contents: Complexity of the lung cancer genome
  • Molecular classification of subtypes
  • Pathways of activation in tumors
  • Intratumoral heterogeneity
  • Targetable alterations in patients
  • Emerging areas in genomics of lung cancer.
1 online resource (viii, 333 p.) Digital: text file; PDF.
  • The Mechanophysiololgy of Stress Fractures in Military Recruits.- Traumatic Brain Injury in the Military: Biomechanics and Finite Element Modelling.- Modeling Skeletal Injuries in Military Scenarios.- Biomechanics of Eye Injury in the Military.- The Biomechanical Basis for Increased Risk of Overuse Musculoskeletal Injuries in Female Soldiers.
  • (source: Nielsen Book Data)9783319330105 20160619
This book provides a state-of-the-art update, as well as perspectives on future directions of research and clinical applications in the implementation of biomechanical and biophysical experimental, theoretical and computational models which are relevant to military medicine. Such experimental and modeling efforts are helpful, on the one hand, in understanding the aetiology, pathophysiology and dynamics of injury development and on the other hand in guiding the development of better equipment and protective gear or devices that should ultimately reduce the prevalence and incidence of injuries or lessen their hazardous effects. The book is useful for military-oriented biomedical engineers and medical physicists, as well as for military physiologists and other medical specialists who are interested in the science and technology implemented in modern investigations of military related injuries.
(source: Nielsen Book Data)9783319330105 20160619
1 online resource ()
1 online resource (XIV, 167 p. 71 ill., 27 illus. in color.) : online resource. Digital: text file; PDF.
  • Cell structure and biochemical reactions.- Cellular homeostasis and membrane potential.- The action potential.- Transport and cell-cell transmission.- Pharmacokinetics.- Skeletal-Muscular System.- Cardiovascular system I: The heart.- Cardiovascular system II: The vasculature.- Respiratory system.- Nervous system.
  • (source: Nielsen Book Data)9783319261959 20160619
This book provides an introduction to qualitative and quantitative aspects of human physiology. It looks at biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, including electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text there are introductions to measuring and quantifying physiological processes using both signal and imaging technologies. Physiology for Engineers describes the basic structure and models of cellular systems, the structure and function of the cardiovascular system, the electrical and mechanical activity of the heart and provides an overview of the structure and function of the respiratory and nervous systems. It also includes an introduction to the basic concepts and applications of reaction kinetics, pharmacokinetic modelling and tracer kinetics. It is of interest to final year biomedical engineering undergraduates and graduate students alike, as well as to practising engineers new to the fields of bioengineering or medical physics.
(source: Nielsen Book Data)9783319261959 20160619
1 online resource (XXII, 827 p. 266 ill., 188 illus. in color.) : online resource. Digital: text file; PDF.
Scholarpedia's Encyclopedia of Touch provides a comprehensive collection of peer-reviewed articles written by leading researchers, detailing our current scientific understanding of tactile sensing and its neural substrates in animals including humans. The encyclopedia allows ideas and insights to be shared between researchers working on different aspects of touch and in different species, including research in synthetic touch systems. In addition, this encyclopedia raises awareness of research in tactile sensing and increases scientific and public interest in the field. The articles address subjects including tactile control, whiskered robots, vibrissal coding, the molecular basis of touch, invertebrate mechanoreception, fingertip transducers and tactile sensing. All the articles in this encyclopedia provide in-depth and state-of-the-art scholarly treatment of the academic topics concerned, making it an excellent reference work for academics, professionals and students.
(source: Nielsen Book Data)9789462391321 20160619
1 online resource.
  • 1 Chapter 1 Biology and Function of Stem Cells.-2 Embryonic Stem Cells for Cardiac Regeneration.-3 Induced Pluripotent Stem Cells for Cardiac Regeneration.-4 Tissue Specific Progenitor/Stem Cells for Cardiac Regeneration.-5 Circadian Rhythms in Stem Cell Biology and Function.-6 MicroRNAs and stem cells: control pluripotency, reprogramming, and lineage commitment.-7 Epigenetic Regulation of Cardiac Regeneration.-8 Stem cell secretome and paracrine activity.-9 . Role of microvescicles and exosomes for intra- and intercardiac communication.-10 Delivery mode for cardiac stem cell therapy.-11 Stem cell therapies for cardiac regeneration: Current burden - future directions.
  • (source: Nielsen Book Data)9783319254258 20160619
This book provides an update of recent advances in the basic and clinical applications of cell-based therapies for myocardial repair and regeneration in ischemic heart disease (IHD) and heart failure (HF). The first sections of the book illuminate basic aspects of stem cells such as definitions, isolation criteria and characterization of embryonic and adult stem cells, as well as pluripotent stem cells and tissue specific progenitor and stem cells. In the following section, the text examines the role of critical regulators of stem cell differentiation in myocardial regeneration, that include circadian rhythyms, microRNAs, epigenetics, microvescicles, and exosomes. The text concludes with a review of the use of stem/progenitor cells in cardiac regeneration and discuss current controversies, unresolved issues, challenges, and future directions. Stem Cells and Cardiac Regeneration is addressed to a wide audience consisting of cardiologists, clinicians, and research scientists, who will learn new concepts in cardiovascular regeneration and repair with special focus on molecular mechanisms and therapeutic potential for cardiovascular regeneration.
(source: Nielsen Book Data)9783319254258 20160619
1 online resource : illustrations.
  • More than the Modeling of Emotions: A foreword.- Modeling Emotions in Robotic Socially Believable Behaving Systems.- The Role of Intention in Cognitive Robotics.- Engagement Perception and Generation for Social Robots and Virtual Agents.- Social Development of Artificial Cognition.- Going Further in Affective Computing: How Emotion Recognition Can Improve Adaptive User Interaction.- Physical and Moral Disgust with Socially Believable Behaving Systems in Different Cultures.- Speaker's Hand Gestures Can Modulate Receiver's Negative Reactions to a Disagreeable Verbal Message.- Laughter Research: a Review of the ILHAIRE Project.- Prosody Enhances Cognitive Infocommunication: Materials from the HuComTech Corpus.- Analysis of Emotional Speech: A review.
  • (source: Nielsen Book Data)9783319310558 20160619
This volume is a collection of research studies on the modeling of emotions in complex autonomous systems. Several experts in the field are reporting their efforts and reviewing the literature in order to shed lights on how the processes of coding and decoding emotional states took place in humans, which are the physiological, physical, and psychological variables involved, invent new mathematical models and algorithms to describe them, and motivate these investigations in the light of observable societal changes and needs, such as the aging population and the cost of health care services. The consequences are the implementation of emotionally and socially believable machines, acting as helpers into domestic spheres, where emotions drive behaviors and actions. The contents of the book are highly multidisciplinary since the modeling of emotions in robotic socially believable systems requires a holistic perspective on topics coming from different research domains such as computer science, engineering, sociology, psychology, linguistic, and information communication. The book is of interest both to experts and students since last research works on a so complex multidisciplinary topic are described in a neat and didactical scientific language.
(source: Nielsen Book Data)9783319310558 20160619
1 online resource. Digital: text file; PDF.
  • Part I. Human Peripheral Nerve.- 1. Ultrastructure of Myelinated and Unmyelinated Axons.- 2. Macrophages, Mastocytes, and Plasma Cells.- 3. Ultrastructure of the Endoneurium.- 4. Ultrastructure of the Perineurium.- 5. Ultrastructure of the Epineurium .- 6. Origin of the Fascicles and Intraneural Plexus.- 7. Macroscopic View of the Cervical Plexus and Brachial Plexus.- 8. Anna Carrera, Francisco Reina.- 9. Macroscopic View of the Lumbar Plexus and Sacral Plexus.- 10. Cross-sectional Microscopic Anatomy of the Sciatic Nerve and its Dissected Branches.- 11. Cross-sectional Microscopic Anatomy of the Sciatic Nerve and Paraneural Sheaths.- 12. Computerized Tomographic Images of Unintentional Intraneural Injection.- 13. Ultrasound View of Unintentional Intraneural Injection.- 14. Histologic Features of Needle-Nerve and Intraneural Injection Injury as Seen on Light Microscopy.- 15. Structure of Nerve Lesions after "In Vitro" Punctures.- 16. Scanning Electron Microscopy View of In Vitro Intraneural Injections.- 17. Injection of Dye Inside the Paraneural Sheath of the Sciatic Nerve in the Popliteal Fossa.- 18. High-Definition and Three-Dimensional Volumetric Ultrasound Imaging of the Sciatic Nerve.- Part II. Component of the Spinal Canal.- 19. Spinal Dural Sac, Nerve Root Cuffs, Rootlets, and Nerve Roots.- 20. Ultrastructure of Spinal Dura Mater.- 21. Ultrastructure of the Spinal Arachnoid Layer.- 22. Three-Dimensional Reconstruction of Spinal Dural Sac.- 23. Three-dimensional Reconstruction of Spinal Epidural Fat.- 24. Ultrastructure of Human Spinal Trabecular Arachnoid.- 25. Ultrastructure of Spinal Pia Mater.- 26. Ultrastructure of Spinal Subdural Compartment: Origin of Spinal Subdural Space.- 27. Unintentional Subdural and Intradural Placement of Epidural Catheters.- 28. Ultrastructure of Human Spinal Nerve Roots.- 29. Three-dimensional Reconstruction of Cauda Equine Nerve Roots.- 30. Spinal Nerve Root Lesions after "In Vitro" Needle Puncture.- 31. Nerve Root Cuff Lesions after "In Vitro" Needle Puncture and Model of "In Vitro" Nerve Stimuli Caused by Epidural Catheters.- 32. Ligamentum Flavum and Related Spinal Ligaments.- 33. The Ligamentum Flavum.- 34. Subarachnoid (Intrathecal) Ligaments.- 35. Displacement of the Nerve Roots of Cauda Equina in Different Positions.- 36. Nerve Root and Types of Needles Used in Transforaminal Injections.- 37. Three-Dimensional Visualization of Spinal Cerebrospinal Fluid and Cauda Equina Nerve Roots, and Estimation of a Related Vulnerability Ratio.- 38. Ultrastructure of Nerve Root Cuffs: Dura-Epineurium Transition Tissue.- 39. Ultrastructure of Nerve Root Cuffs: Arachnoid Layer-Perineurium Transition Tissue at Preganglionic, Ganglionic, and Postganglionic Levels.- 40. Spinal Cord Stimulation.- 41. Ultrastructure of Dural Lesions Produced in Lumbar Punctures.- 42. Injections of Particulate Steroids for Nerve Root Blockade: Ultrastructural Examination of Complicating Factors.- 43. Nerve Root and Types of Needles Used in Transforaminal Injections.- Part III. Materials.- 44. Needles in Regional Anesthesia.- 45. Catheters in Regional Anesthesia.- 46. Epidural Filters and Particles from Surgical Gloves.- Part IV. Research Techniques.- 47. Three-dimensional Reconstruction of Spinal Cerebrospinal Fluid, Roots, and Surrounding Structures.- 48. Cerebrospinal Fluid and Root Volume Quantification from Magnetic Resonance Images.- 49. Scanning Electron Microscopy.- 50. Transmission Electron Microscopy.
  • (source: Nielsen Book Data)9783319095219 20160618
This is the first atlas to depict in high-resolution images the fine structure of the spinal canal, the nervous plexuses, and the peripheral nerves in relation to clinical practice. The Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine contains more than 1500 images of unsurpassed quality, most of which have never been published, including scanning electron microscopy images of neuronal ultrastructures, macroscopic sectional anatomy, and three-dimensional images reconstructed from patient imaging studies. Each chapter begins with a short introduction on the covered subject but then allows the images to embody the rest of the work; detailed text accompanies figures to guide readers through anatomy, providing evidence-based, clinically relevant information. Beyond clinically relevant anatomy, the book features regional anesthesia equipment (needles, catheters, surgical gloves) and overview of some cutting edge research instruments (e.g. scanning electron microscopy and transmission electron microscopy). Of interest to regional anesthesiologists, interventional pain physicians, and surgeons, this compendium is meant to complement texts that do not have this type of graphic material in the subjects of regional anesthesia, interventional pain management, and surgical techniques of the spine or peripheral nerves.
(source: Nielsen Book Data)9783319095219 20160618
1 online resource (1 streaming video file (43 min.) : color, sound).
  • Contents: Spinal anatomy
  • Where back pain comes from
  • Forces acting on the spine
  • Mechanisms of injury to the lumbar spine
  • Predisposition to injury: "vulnerable" tissues
  • Spinal degeneration
  • "Functional pathology".

14. Circadian medicine [2015]

1 online resource (xviii, 353 pages)
  • Machine generated contents note: Part I: Fundamental ConceptsIntroduction: Colwell1. Molecular clockwork and the determinants of human circadian clock Steve Brown, University of Zurich, 2.SCN Circuitry with a focus on outputs including ANS, body temperature Rae Silver, Columbia University, Ruud Buijs, Universidad Nacional Autonoma de Mexico3. Sleep and circadian rhythms: partners in the regulation of behavior. Mistlberger RE, Simon Fraser University, Burnaby, BC, Canada OR T. Deboer, Leiden University, NL4. Circadian Sleep disorders Phyllis C. Zee, Sleep Disorders Center, Northwestern University OR Derk-Jan Dijk, University of Surrey5. Sleep and circadian rhythms: reciprocal partners in the regulation of behavior. Mistlberger RE, Simon Fraser University, Burnaby, BC, Canada or T. Deboer, Leiden Univeristy, NL6. Circadian regulation of arousal and role in chronic fatigue / Mary Harrington, Smith College Part II: Circadian regulation of major organ system7. Physiology of the adrenal and liver circadian clocks / Henrik Oster, Max-Planck Institute Biophysical Chemistry Goettingen Germany8. Nutrition and diet as potent regulators of the liver clock. Shigenobu Shibata; Waseda University, Tokyo, Japan; 9. Desynchrony of the human circadian system as a cause of pathophysiology in the heart and pancreas.Frank Scheer, Harvard University, 10. Cardiomyocyte circadian clock OR Circadian Clocks in the Vasculature M.E. Young, University of Alabama; Garret A. Fitzgerald, M.D (University of Pennsylvania)11. Integration of Circadian Mechanisms and Energy Balance Joseph Bass, Northwestern University12. Disruption of circadian rhythms and development of diabetes Aleksey V. Matveyenko, University of California Los Angeles13. Respiratory clocks Hitoshi Okamura, Kyoto University, Japan14. Circadian clock control of the cellular response to DNA damage and cancer. Sancar, A, University of North Carolina School of Medicine, Chapel Hill, NCPart III: clocks in the central nervous system:15. Sleep and circadian regulation of vigilance and cognitive performance in humans Ken P Wright, Jr. Center for Neuroscience, University of Colorado, Boulder, CO16. Circadian clock, reward, and addictive behaviors Albrecht U, University of Fribourg, Fribourg, Switzerland:17. Circadian rhythms and mood disorders McClung, CA; University of Pittsburgh Medical School, 18. Circadian regulation of memory processes Colwell CSPart IV: Aging and neurodegeneration19. Is circadian dysfunction an integral symptom of Schizophrenia? Foster RG, University of Oxford, Oxford, UK20. Alzheimer's disease and the mistiming of behavior. Antle M, University of Calgary, Calgary, Canada21. Circadian dysfunctional in Huntington's disease Morton AJ, University of Cambridge, Cambridge, United Kingdom22. The Aging clock Block GD, University of California Los Angeles:23. Social jet lag and the costs of 24/7 society Till Roenneberg, Ludwig-Maximilians-University Munich24. How shift work and a destabilized circadian system may increase risk for development of cancer and type 2 diabetes. Eva Schemhammer, Harvard University.
Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease, will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.
(source: Nielsen Book Data)9781118467787 20160618
online resource (ix, 468 pages) : illustrations (some color)
  • The body
  • The Cell
  • Tissues
  • General features of the skeleton
  • General features of the muscles
  • Anatomical terms and their Latin equivalents
  • Trunk
  • Anatomical terms and their Latin equivalents
  • Upper Limb
  • Bones, ligaments and joints
  • Muscles, fascias, and special features
  • Anatomical terms and their Latin equivalents
  • Lower Limb
  • Bones, ligaments, joints
  • Muscles, fascias, and special features
  • Anatomical terms and their Latin equivalents
  • Head and Neck
  • Skull
  • Muscles and fascias
  • Anatomical terms and their Latin equivalents
  • Topography of peripheral nerves and vessels
  • Head and neck
  • Upper limb
  • Trunk
  • Lower limb
  • Anatomical terms and their Latin equivalents.
Medical Library (Lane)
1 online resource (1 streaming video file (43 min.) : color, sound).
  • Contents: Phenotypic diversity in human populations
  • Selective sweeps
  • Clines of allele frequency
  • Selection on standing variation
  • Polygenic adaptations
  • Adaptive introgression
  • Adaptations to high altitude
  • Genome-wide evidence for local adaptations
  • Interpreting the results of selection scans
  • Convergent adaptations.
1 PDF (xv, 116 pages).
  • 1. Introduction and scope
  • 1.1 Definitions
  • 1.2 User engagement vs. user experience
  • 1.3 Characteristics
  • 1.3.1 Focused attention
  • 1.3.2 Positive affect
  • 1.3.3 Aesthetics appeal
  • 1.3.4 Endurability
  • 1.3.5 Novelty
  • 1.3.6 Richness and control
  • 1.3.7 Reputation, trust, and expectation
  • 1.3.8 User context, motivation, incentives, and benefits
  • 1.4 Measurements
  • 1.5 Scope
  • 1.6 Structure
  • 2. Approaches based on self-report methods
  • 2.1 Self-report approaches
  • 2.2 Advantages and limitations of self-report methods
  • 2.2.1 Communication
  • 2.2.2 Methodology bias
  • 2.2.3 Reliability and validity
  • 2.3 Interviews
  • 2.3.1 Types of interviews
  • 2.3.2 Applying interviews to measure user engagement
  • 2.4 Think aloud and think after protocols
  • 2.4.1 Think aloud
  • 2.4.2 Think after
  • 2.4.3 Relationship to user engagement
  • 2.5 Questionnaires
  • 2.6 Questionnaires for measuring user engagement
  • 2.6.1 Survey to evaluate engagement
  • 2.6.2 Engagement and influences on questionnaire
  • 2.6.3 User engagement scale
  • 2.6.4 eHealth engagement scale
  • 2.7 Constructs related to user engagement
  • 2.7.1 Mental workload
  • 2.7.2 Disorientation
  • 2.7.3 Playfulness
  • 2.7.4 Cognitive absorption
  • 2.8 Summary
  • 3. Approaches based on physiological measurements
  • 3.1 Psychophysiological measurements
  • 3.2 Facial expressions
  • 3.3 Eye tracking
  • 3.3.1 Eye tracking and search
  • 3.3.2 Eye tracking and reading
  • 3.3.3 Eye tracking and selection
  • 3.3.4 Summary and limitations
  • 3.4 Cursor tracking
  • 3.4.1 Aligning eye gaze and mouse movement
  • 3.4.2 Mouse movement in search
  • 3.4.3 Mouse movement elsewhere
  • 3.5 Summary
  • 4. Approaches based on web analytics
  • 4.1 Intra-session vs. inter-session engagement
  • 4.2 Some dimensions of online measurements
  • 4.2.1 Dependence on the type of website
  • 4.2.2 Dependence on the type of user
  • 4.2.3 Dependence on the task
  • 4.3 Large-scale measurements
  • 4.4 Intra-session measurements
  • 4.4.1 Dwell time and similar measures
  • 4.4.2 Revisits to a site
  • 4.4.3 Clickthrough rate
  • 4.4.4 Number of pages viewed
  • 4.4.5 Other measurements
  • 4.5 Inter-session measurements
  • 4.5.1 Direct value measurement
  • 4.5.2 Total use measurement
  • 4.5.3 Return-rate measurement
  • 4.6 Summary
  • 5. Beyond desktop, single site, and single task
  • 5.1 Measuring for online multitasking
  • 5.2 Measuring on a network of sites
  • 5.3 Measuring in mobile information seeking
  • 5.4 Summary
  • 6. Enhancing the rigor of user engagement methods and measures
  • 6.1 Scale
  • 6.2 Setting
  • 6.3 Temporality
  • 6.4 Objectivity and subjectivity
  • 6.5 Process- and product-based
  • 6.6 Summary
  • 7. Conclusions and future research directions
  • 7.1 Summary
  • 7.2 Future research directions
  • 7.3 Take-aways
  • Bibliography
  • Authors' biographies
  • Index.
User engagement refers to the quality of the user experience that emphasizes the positive aspects of interacting with an online application and, in particular, the desire to use that application longer and repeatedly. User engagement is a key concept in the design of online applications (whether for desktop, tablet or mobile), motivated by the observation that successful applications are not just used, but are engaged with. Users invest time, attention, and emotion in their use of technology, and seek to satisfy pragmatic and hedonic needs. Measurement is critical for evaluating whether online applications are able to successfully engage users, and may inform the design of and use of applications. User engagement is a multifaceted, complex phenomenon; this gives rise to a number of potential measurement approaches. Common ways to evaluate user engagement include using self-report measures, e.g., questionnaires; observational methods, e.g. facial expression analysis, speech analysis; neuro-physiological signal processing methods, e.g., respiratory and cardiovascular accelerations and decelerations, muscle spasms; and web analytics, e.g., number of site visits, click depth. These methods represent various trade-offs in terms of the setting (laboratory versus "in the wild"), object of measurement (user behaviour, affect or cognition) and scale of data collected. For instance, small-scale user studies are deep and rich, but limited in terms of generalizability, whereas large-scale web analytic studies are powerful but negate users' motivation and context. The focus of this book is how user engagement is currently being measured and various considerations for its measurement. Our goal is to leave readers with an appreciation of the various ways in which to measure user engagement, and their associated strengths and weaknesses. We emphasize the multifaceted nature of user engagement and the unique contextual constraints that come to bear upon attempts to measure engagement in different settings, and across different user groups and web domains. At the same time, this book advocates for the development of "good" measures and good measurement practices that will advance the study of user engagement and improve our understanding of this construct, which has become so vital in our wired world.
1 online resource.
  • Preface-- Part I. Materials and Their Properties: 1. Introduction to orthopaedic biomechanics-- 2. Materials and their properties-- Part II. Engineering Theory Applied to Orthopaedics: 3. Modes of loading of the musculoskeletal system-- 4. Biomechanics of fracture-- 5. Biotribology-- Part III. Clinical Biomechanics: 6. Biomechanics of the hip and THR-- 7. Biomechanics of the knee and TKR-- 8. Biomechanics of the shoulder-- 9. Biomechanics of the elbow-- 10. Biomechanics of the spine-- 11. Biomechanics of the foot and ankle-- 12. Biomechanics of fracture fixation-- 13. Trauma meeting: case-based discussions-- Index.
  • (source: Nielsen Book Data)9781107685468 20160618
Orthopaedic surgeons require not only an understanding of anatomy and clinical sciences, and competence in surgical skills, but also a strong foundation in biomechanics. The application of biomechanics plays an increasing role in modern orthopaedics; for example, correct decisions about the mode of treatment and choice of implants are just as important as operating precisely to reach a specific anatomical landmark. This book simplifies the core principles in orthopaedic biomechanics, giving readers the solid grounding they need to flourish in the specialty. Each topic is covered in a discrete, double-page spread, featuring concise text accompanied by illustrations or tables to give readers a solid understanding of the concepts discussed. This is a must-read guide for orthopaedic trainees at every level, and will be valuable for biomechanical researchers and other professionals in the field.
(source: Nielsen Book Data)9781107685468 20160618
1 online resource. Digital: text file; PDF.
  • Peroxynitrite induces degradation of myosin heavy chain via p38 MAPK and muscle-specific E3 ubiquitin ligases in C2 skeletal myotubes. O. Rom, S. Kaisari, A.Z. Reznick, and D. Aizenbud Alterations in the coagulation system of active smokers from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. G. Delgado, R. Siekmeier, T.B. Grammer, B.O. Boehm, W. Marz, and M.E. Kleber. C-reactive protein and lipoprotein-associated phospholipase A2 in smokers and nonsmokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study. M.E. Kleber, R. Siekmeier, G. Delgado, T.B. Grammer, B.R. Winkelmann, H. Scharnagl, B.O. Boehm, and W. Marz Green tea drinking improves erythrocytes and saliva oxidative status in the elderly. B. Narotzki, A.Z. Reznick, T. Mitki, D. Aizenbud, and Y. Levy Cardiovascular effects of N-acetylcysteine in meconium-induced acute lung injury. D. Mokra, I. Tonhajzerova, H. Pistekova, Z. Visnovcova, A. Drgova, J. Mokry, and A. Calkovska Alterations in vagal-immune pathway in long-lasting mental stress. Z. Visnovcova, D. Mokra, P. Mikolka, M. Mestanik, A. Jurko, M. Javorka, A. Calkovska, and I. Tonhajzerova Nocturnal parasympathetic modulation of heart rate in obesity-hypoventilation patients. A. Brzecka, M. Pawelec-Winiarz, A. Teplicki, P. Piesiak, and R. Jankowska N-acetylcysteine Alleviates the Meconium-Induced Acute Lung Injury. D. Mokra, A. Drgova, M. Petras, J. Mokry, M. Antosova, and A. Calkovska.
  • (source: Nielsen Book Data)9783319097213 20160618
Cardiorespiratory function is prominently affected by oxidative stress. Cigarette smoking is the archetype of oxidative and nitrative stress and free radical formation. New adverse effects of smoking keep on propping up in research. The chapters provide the comprehensive view of new developments in this area regarding cardiovascular and lung function and muscle catabolism. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented. Much less is known about the effect of cognitive stress on vagally-mediated cardiorespiratory function and surprisingly, on vagal immune pathway. The experimental studies also show that clinically important meconium aspiration syndrome contains an oxidative trait which is amenable to antioxidative treatment. This volume creates a source of information on the damaging role of oxidative stress in cardiorespiratory function that has by far not been available.
(source: Nielsen Book Data)9783319097213 20160618
1 online resource (1 streaming video file (29 min.) : color, sound).
  • Contents: Concepts and pathways in intracellular trafficking
  • Disorders affecting specific trafficking steps
  • Arthrogryposis-Renal dysfunction-Cholestasis (ARC) syndrome
  • ARC syndrome as an example of a trafficking disorder.