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• 1 Introduction
• 2 Mechanistic Aspects of Carbon-Boron Bond Formation
• 3 Diboron Compounds: Synthesis and Applications
• 4 Synthesis of gem-Diboron Compounds from Diboron Reagents
• 5 anti Boron Addition to Alkynes
• 6 Borylation of Carbonyl and Imine Groups
• 7 Borylative Ring Opening
• 8 Borylative Ring Closing
• 9 Decarbonylative/Decarboxylative Borylation
• 10 Borylation Reactions in Water
• 11 Nanocatalyzed Borylation Reactions
• 12 Reactions through Radical Boryl Moieties
• 13 Boron "Ate" Complexes for Asymmetric Synthesis
• 14 Application of Selective Asymmetric Borylation to Target Compounds.
• (source: Nielsen Book Data)

Harnessing the versatile reactivity of boron for organic synthesis The widespread use of organoboron compounds justifies the efforts devoted to their synthesis, as well as toward developing an understanding of their reactivity. The nature of the mono- or diboron species is of paramount importance in determining the reversible covalent binding properties of the boron atom with both nucleophiles and electrophiles. By wedding the rich chemical potential of organoboron compounds to the ubiquity of organic scaffolds, advanced borylation reactions have the potential to open unprecedented synthetic alternatives, and new knowledge in the field should encourage chemists to use organoboron compounds. In this volume, the main objective is to provide a collection of the most useful, practical, and reliable methods, reported mainly within the last decade, for boron activation and boron reactivity. The volume covers the main concepts of organoboron compounds and includes experimental procedures, enabling newcomers to the field the instant and reliable application of the new tools in synthesis. Rather than aiming for a comprehensive coverage, the most advanced solutions for challenging transformations are introduced. To this end, a team of pioneers and leaders in the field have been assembled who discuss both the practical and conceptual aspects of this rapidly growing field.
(source: Nielsen Book Data)

• Volume 1. Polyene cyclizations
• Cation-pi cyclizations of epoxides and polyepoxides
• Metathesis reactions
• Enyne-metathesis-based domino reactions in natural product synthesis
• Domino metathesis reactions involving carbonyls
• Radical reactions
• Peroxy radical additions
• Radical cyclizations
• Tandem radical processes
• Non-radical skeletal rearrangements
• Protic acid/base induced reactions
• Lewis acid/base induced reations
• Brook rearrangement as the key step in domino reactions
• Metal-mediated reactions
• Palladium-mediated domino-reactions
• Dirhodium-catalyzed domino reactions
• Gold-mediated reactions
• Rare earth metal mediated domino reactions
• Cobalt and other metal mediated domino reactions: the Pauson-Khand reaction and its use in natural product total synthesis.

• Volume 2. Pericyclic reactions
• The Diels-Alder cycloaddition reaction in the context of domino processes
• Domino reactions including [2+2], [3+2], or [5+2] cycloadditions
• Domino transformations involving an electrocyclization reaction
• Sigmatropic shifts and Ene reactions (excluding [3,3])
• Domino transformations initiated by of proceeding through [3,3]-sigmatropic rearrangements
• Intermolecular alkylative dearomatization of phenolic derivatives in organic synthesis
• Additions to alkenes and C=O and C=N bonds
• Additions to nonactivated C=C bonds.

Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds.

• 1. Lewis base and acid catalysts
• 2. Brønsted base and acid catalysts, and additional topics / volume editor: K. Maruoka.

• 1. Additions to alkenes, alkynes, and carbonyl compounds / authors, R. Ballini [and 25 others]
• 2. Alkenations, cross couplings, insertions, substitutions, and halomethylations / authors, R. Ballini [and 33 others].

• Note continued:
• 12.3.3. Aerobic Hetaryl-Hetaryl Oxidative Cross Coupling / L.A. Perego / F. Bellina
• 12.4. Aerobic Oxidative Alkynylation of Arenes and Hetarenes / F. Bellina / L.A. Perego
• 12.4.1. Copper-Promoted Aerobic Oxidative Alkynylation of Arenes and Hetarenes / F. Bellina / L.A. Perego
• 12.4.1.1. Alkynylation of Perfluoroarenes / F. Bellina / L.A. Perego
• 12.4.1.2. Alkynylation of Hetarenes / L.A. Perego / F. Bellina
• 12.4.1.3. Copper-Promoted Alkynylation of Arenes and Hetarenes Using Directing Groups / F. Bellina / L.A. Perego
• 12.4.2. Palladium-Catalyzed Aerobic Oxidative Alkynylation of Hetarenes / F. Bellina / L.A. Perego
• 12.4.2.1. Alkynylation of Azoles / F. Bellina / L.A. Perego

• Machine generated contents note:
• 2.1. Photocatalytic Oxidation / K. Muniz
• 2.1. Photocatalytic Oxidation / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1. Triplet Oxygen Trapping of Photogenerated Radicals / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1.1. Trapping of Monoradicals / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1.1.1. Radical Addition to Alkenes To Generate Carbon Radicals / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1.1.2. Hydrogen Abstraction To Generate Carbon Radicals / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1.1.3. Deprotonation of Radical Cations To Generate Carbon Radicals / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1.2. Trapping of Radical Cations / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.1.3. Trapping of Biradicals / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.2. Photochemical Superoxide Generation and Reactions / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.2.1. Aromatic Hydroxylation via Arylboronates / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.2.2. Benzylic Oxidation via Acridinium Photocatalysis / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.2.3. Benzylic Activation by Electron-Transfer-Initiated C-H Bond Cleavage and Radical Trapping with Superoxide / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.2.4. Benzylic Activation by Electron-Transfer-Initiated C-C Bond Cleavage and Radical Trapping with Superoxide / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.2.5. Benzylic Activation by Electron Transfer and Radical Cation Trapping with Superoxide / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.3. Photochemical Singlet Oxygen Generation and Reaction / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.3.1. Singlet Oxygen Ene Reactions / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.3.2. Singlet Oxygen [4+2]-Cycloaddition Reactions / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.3.3. Singlet Oxygen [2+2]-Cycloaddition Reactions / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.3.4. Singlet Oxygen Heteroatom Oxidation / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.1.4. Miscellaneous Photooxidation Processes / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.2. Catalytic Oxidations with Hypervalent Iodine / A.G. Griesbeck / M. Kleczka / S. Sillner
• 2.2. Catalytic Oxidations with Hypervalent Iodine / T. Wirth / F.V. Singh
• 2.2.1. Oxidation Reactions Using Iodoarenes as Precatalysts / T. Wirth / F.V. Singh
• 2.2.1.1. Iodine(III)-Catalyzed Oxidation Reactions / T. Wirth / F.V. Singh
• 2.2.1.1.1. Iodine(III)-Catalyzed Oxidation of Alcohols / T. Wirth / F.V. Singh
• 2.2.1.1.2. Iodine(III)-Catalyzed Oxidation of Phenols / T. Wirth / F.V. Singh
• 2.2.1.1.2.1. Iodine(III)-Catalyzed Oxidation of Phenols without Cyclization / T. Wirth / F.V. Singh
• 2.2.1.1.2.2. Iodine(III)-Catalyzed Oxidation of Phenols with Cyclization / T. Wirth / F.V. Singh
• 2.2.1.1.3. Iodine(III)-Catalyzed Oxidation of Alkylarenes / T. Wirth / F.V. Singh
• 2.2.1.1.4. Iodine(III)-Catalyzed Oxidation of Alkenes and Alkynes / T. Wirth / F.V. Singh
• 2.2.1.2. Iodine(V)-Catalyzed Oxidation Reactions / T. Wirth / F.V. Singh
• 2.2.1.2.1. Iodine(V)-Catalyzed Oxidation of Alcohols / T. Wirth / F.V. Singh
• 2.2.1.2.1.1. 1-Hydroxy-1,2-benziodoxo1-3(1H)-one 1-Oxide Catalyzed Oxidation of Alcohols / T. Wirth / F.V. Singh
• 2.2.1.2.1.2. 2-Iodylbenzenesulfonic Acid Catalyzed Oxidation of Alcohols / T. Wirth / F.V. Singh
• 2.2.1.2.1.3. Iodylbenzene-Catalyzed Oxidation of Alcohols / T. Wirth / F.V. Singh
• 2.2.1.2.2. Iodine(V)-Catalyzed Oxidation of Phenols / T. Wirth / F.V. Singh
• 2.2.1.2.3. Iodine(V)-Catalyzed Oxidation of Alkylarenes / T. Wirth / F.V. Singh
• 2.2.1.3. Hypervalent Iodine Catalyzed Enantioselective Oxidation Reactions / T. Wirth / F.V. Singh
• 2.3. Water as an Oxygen Source for Oxidation Reactions / T. Wirth / F.V. Singh
• 2.3. Water as an Oxygen Source for Oxidation Reactions / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.3.1. Preliminary Considerations / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.3.2. Case Studies on the Use of Water as an Oxygen Source / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.3.2.1. Organic Substrate Oxidation Reactions with Water and Light Using a Manganese Porphyrin Complex as Catalyst / F. Maseras / A. Llobet / C. Gimbert-Surinach / I. Funes-Ardoiz / P. Farras / R. Garrido-Barros
• 2.3.2.2. Photocatalytic Oxidation of Sulfides and Benzylic Alcohols Using Water, Oxoruthenium(IV)-Based Catalysts, and Bismuth Vanadate / R. Garrido-Barros / I. Funes-Ardoiz / P. Farras / C. Gimbert-Surinach / F. Maseras / A. Llobet
• 2.3.2.3. Oxidation of Alcohols to Carboxylic Acids Using Water as the Oxygen Source: A One-Pot Process with a Ruthenium Pincer Complex / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.3.3. Integral Photoelectrochemical Cells / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.3.4. Conclusions / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.4. Dehydrogenation / R. Garrido-Barros / I. Funes-Ardoiz / A. Llobet / C. Gimbert-Surinach / F. Maseras / P. Farras
• 2.4. Dehydrogenation / T. Ikariya / Y. Kayaki
• 2.4.1. Transfer Dehydrogenation of Alcohols / T. Ikariya / Y. Kayaki
• 2.4.2. Aerobic Dehydrogenation of Alcohols / T. Ikariya / Y. Kayaki
• 2.4.3. Acceptorless Dehydrogenation of Alcohols and Amines / T. Ikariya / Y. Kayaki
• 2.4.3.1. Acceptorless Dehydrogenation of Alcohols / T. Ikariya / Y. Kayaki
• 2.4.3.2. Acceptorless Dehydrogenative Coupling of Alcohols / T. Ikariya / Y. Kayaki
• 2.4.3.2.1. Synthesis of Esters and Lactones / T. Ikariya / Y. Kayaki
• 2.4.3.2.2. Acceptorless Dehydrogenation of Alcohols Combined with Dehydrative Condensations / T. Ikariya / Y. Kayaki
• 2.4.3.3. Acceptorless Dehydrogenative Coupling of Alcohols and Amines / T. Ikariya / Y. Kayaki
• 2.4.3.3.1. Synthesis of Carboxamides and !mines / T. Ikariya / Y. Kayaki
• 2.4.3.3.2. Synthesis of Heterocycles / T. Ikariya / Y. Kayaki
• 2.4.3.4. Acceptorless Dehydrogenation of Amines / T. Ikariya / Y. Kayaki
• 2.4.4. Dehydrogenation of Alkanes / T. Ikariya / Y. Kayaki
• 2.4.4.1. Dehydrogenation of Hydrocarbons / T. Ikariya / Y. Kayaki
• 2.4.4.2. Dehydrogenation of Aldehydes and Ketones as Functionalized Alkanes / T. Ikariya / Y. Kayaki
• 2.5. Biomimetic Oxidation in Organic Synthesis / T. Ikariya / Y. Kayaki
• 2.5. Biomimetic Oxidation in Organic Synthesis / L. Vicens / M. Costas / M. Borrell
• 2.5.1. P450-like Oxidations and Related Reactions / L. Vicens / M. Costas / M. Borrell
• 2.5.1.1. Metalloporphyrins as C-H Oxidation Catalysts / L. Vicens / M. Costas / M. Borrell
• 2.5.1.2. Halide and Pseudohalide Transfer with Metalloporphyrins / L. Vicens / M. Costas / M. Borrell
• 2.5.2. Non-Heme Iron-Dependent Oxygenases as Models for Oxidation Catalysts / L. Vicens / M. Costas / M. Borrell
• 2.5.2.1. C-H Oxidations with Non-Heme Iron Complexes / L. Vicens / M. Costas / M. Borrell
• 2.5.2.2. Iron-Catalyzed syn-Dihydroxylation / L. Vicens / M. Costas / M. Borrell
• 2.5.2.3. Iron-Catalyzed Asymmetric cis-Dihydroxylation / L. Vicens / M. Costas / M. Borrell
• 2.5.2.4. Iron-Catalyzed Epoxidation / L. Vicens / M. Costas / M. Borrell
• 2.5.2.5. Iron-Catalyzed Asymmetric Epoxidation / L. Vicens / M. Costas / M. Borrell
• 2.5.3. Copper-Catalyzed Biomimetic Oxidations / L.

• Vicens / M. Costas / M. Borrell
• 2.5.3.1. Selective Aliphatic C-H Oxidation with Dicopper Complexes / L. Vicens / M. Costas / M. Borrell
• 2.5.3.2. Galactose Oxidase Related Oxidations / L. Vicens / M. Costas / M. Borrell
• 2.5.3.2.1. Alcohol Oxidation with Copper Compounds and 2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) and Related Radicals / L. Vicens / M. Costas / M. Borrell
• 2.5.3.3. ortho-Hydroxylation of Phenols with Tyrosinase Models / L. Vicens / M. Costas / M. Borrell
• 3. Metal-Catalyzed Oxidation of Alkanes To Give Esters or Amines / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.1. Metal-Catalyzed Oxidation of Alkanes to Esters Using Diazo Compounds / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.1.1. Seminal Studies in Carbene Transfer to C-H Bonds of Alkanes / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.1.2. Rhodium-Based Catalysts / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.1.3. Coinage-Metal-Based Catalysts / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.1.4. Catalysts Based on Other Metals / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.1.5. Methane and Gaseous Alkanes as Substrates / M.M. Diaz-Requejo / A. Caballero / P.J. Perez
• 3.1.6. Asymmetric Carbene Insertion from Diazo Compounds / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.2. Metal-Catalyzed Oxidation of Alkanes to Amines / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.2.1. Alkane Conversion into Amines by Nitrene Insertion / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.2.1.1. Cycloalkanes as Substrates / A. Caballero / P.J. Perez / M.M. Diaz-Requejo
• 3.2.1.1.1. Using Isolated Hypervalent Iodine(III) Sources / A. Caballero / P.J. Perez / M.M. Diaz-Requejo

Catalytic reductions are among the most used synthetic transformations, and the past 15 years have seen great progress in this field. Science of Synthesis: Catalytic Reduction in Organic Synthesis includes the latest developments, as well as selective coverage of more well-established methods. Both heterogeneous and homogeneous catalytic systems are covered, and enantioselective methodology is well represented. There is a focus on the use of metal nanoparticles, both in suspension as well as on solid supports. Furthermore, the advent of research on the conversion of renewable resources into fuels and chemicals has given a great impetus to the field, as deoxygenations are often the first step in the conversion of biomass and this can often be achieved using hydrogenation or hydrogenolysis reactions. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included.
(source: Nielsen Book Data)

• 1. Catalytic transformations via C-H activation 1 / volume editors,
• 2. Catalytic transformations via C-H activation 2 / volume editor, J.-Q. Yu

• 1. C-C Cross coupling using organometallic partners / volume editor, G.A. Molander
• 2. Carbon-heteroatom cross coupling and C-C cross coupling of acidic C-H nucleophiles / volume editor, J.P. Wolfe
• 3. Metal-catalyzed heck-type reactions and C-C cross-coupling via C-H activation / volume editor, M. Larhed.

• 1.1 Metal/Metal Dual Catalysis 1.1.1 General Principles of Metal/Metal Dual Catalysis 1.1.2 Palladium/Copper and Palladium/Nickel Dual Catalysis 1.1.3 Rhodium/Palladium Dual Catalysis 1.1.4 Iridium/Zinc and Iridium/Copper Dual Catalysis 1.1.5 Gold/Iron Dual Catalysis 1.1.6 Gold Dual Catalysis with Palladium, Nickel, or Rhodium 1.1.7 Gold/Gold Dual Catalysis 1.2 Transition-Metal/Photocatalyst Dual Catalysis 1.2.1 General Principles of Transition-Metal/Photocatalyst Dual Catalysis 1.2.2 Nickel/Photocatalyst Dual Catalysis 1.2.3 Palladium/Photocatalyst Dual Catalysis 1.2.4 Gold/Photocatalysis Dual Catalysis.
• (source: Nielsen Book Data)

• 2.1 Metal/Organocatalyst Dual Catalysis 2.1.1 General Principles of Metal/Organocatalyst Dual Catalysis 2.1.2 Palladium/Organocatalyst Dual Catalysis 2.1.3 Gold/Organocatalyst Dual Catalysis 2.1.4 Rhodium/Organocatalyst Dual Catalysis 2.2 Metal/Biocatalyst Dual Catalysis 2.3 Dual Catalysis with Two Organocatalysts 2.4 Organocatalyst/Photocatalyst Dual Catalysis 2.5 Organocatalyst/Biocatalyst Dual Catalysis 2.6 Dual Catalysis with Two or More Biocatalysts.
• (source: Nielsen Book Data)

The field of dual catalysis has developed rapidly over the last decade, and these volumes define its impact on organic synthesis. The most important, basic concepts of synergistic, dual catalytic cycles are introduced, providing newcomers to the field with reliable information on this new approach to facilitating the synthesis of organic molecules. Background information and reliable procedures for challenging transformations in synthesis are presented, applying the concept of cooperative dual catalysis as a means of increasing molecular complexity in the most efficient manner. The most useful, practical, and reliable methods for dual catalysis combining metal catalysts, organocatalysts, photocatalysts, and biocatalysts are presented.
(source: Nielsen Book Data)

• 1. General discussion and reactions involving a carbonyl compound as electrophilic component / volume editor, T.J.J. Müller

The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.
(source: Nielsen Book Data)

• 1 Introduction
• 2 Photocatalysis: The Principles
• 3 Practical Aspects of Photocatalysis
• 4 Photocatalytic Oxidative C-C Bond Formation
• 5 Decarboxylative Coupling Reactions
• 6 Proton-Coupled Electron Transfer
• 7 Organocatalysis with Amines in Photocatalysis
• 8 Copper-Based Photocatalysts for Visible-Light-Mediated Organic Transformations
• 9 Gold in Photocatalysis
• 10 Palladium in Photocatalysis
• 11 Nickel in Photocatalysis
• 12 Acridinium Dyes and Quinones in Photocatalysis
• 13 Flavins in Photocatalysis
• 14 Organic Dyes in Photocatalytic Reductive C-H Arylations
• 15 Silicates in Photocatalysis
• 16 Photocatalytic Cycloadditions
• 17 Photocatalytic Carbon-Heteroatom Bond Formation
• 18 Photocatalytic Introduction of Fluorinated Groups
• 19 Heterogeneous Photocatalysis in Organic Synthesis
• 20 Photocatalysis in the Pharmaceutical Industry.
• (source: Nielsen Book Data)

The field of photocatalysis has developed rapidly over the last decade and it is time to clarify its impact on organic synthesis. This volume is an opportunity to provide the defining and current reference work for this field. A primary objective is to collect together the most useful, practical, and reliable methods for photocatalysis and to introduce them to a larger audience. The fundamental concepts of photophysics are introduduced and laboratory set-ups are described, enabling newcomers to the field to instantly apply these new tools in synthesis. Rather than aiming for comprehensive coverage, solutions for challenging transformations in synthesis applying visible light and suitable dyes are presented. A team of pioneers and leaders in the field has been assembled, who discuss both the practical and conceptual aspects of this rapidly growing field. Scope, limitations, and mechanism of the reactions are covered and key experimental procedures are included.
(source: Nielsen Book Data)

• Oxidation
• Reduction
• Halogenation / authors, E. Smeaton, M.H. Smith and M.J. White.

• 1. Stereoselective reactions of carbon-carbon double bonds / volume editor, Johannes G. de Vries
• 2. Stereoselective reactions of carbonyl and imino groups / volume editor, G.A. Molander
• 3. Stereoselective pericyclic reactions, cross coupling, and C-H and C-X activation / volume editor, P. Andrew Evans.