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1. Molecular biology [2005]

xiv, 370 p. : ill. ; 25 cm.
  • A: Cells and Macromolecules - Cellular classification-- Subcellular organelles-- Macromolecules-- Large macromolecular assemblies. B: Protein Structure - Amino acids-- Protein structure and function-- Protein analysis C: Properties of Nucleic Acids - Nucleic acid structure-- Chemical and physical properties of nucleic acids-- Spectroscopic and thermal properties of nucleic acids-- DNA supercoiling D: Prokaryotic and Eukaryotic Chromosome Structure - Prokaryotic chromosome structure-- Chromatin structure-- Eukaryotic chromosome structure-- Genome complexity-- The flow of genetic information E: DNA Replication - DNA replication: an overview-- Bacterial DNA replication-- The cell cycle-- Eukaryotic DNA replication F: DNA Damage - Repair and Recombination-- Mutagenesis-- DNA damage-- DNA repair-- Recombination G: Gene Manipulation - DNA cloning (an overview)-- Preparation of plasmid DNA-- Restriction enzymes and electrophoresis-- Ligation, transformation and analysis of recombinants H: Cloning Vectors - Design of plasmid vectors-- Bacteriophage vectors-- Cosmids and YACs-- Eukaryotic vectors I: Gene Libraries and Screening - Genomic libraries-- cDNA libraries-- Screening procedures J:Analysis and Uses of Cloned DNA - Characterisation of clones-- Sequencing nucleic acids-- PCR-- Organization of cloned genes-- Mutagenesis of cloned genes-- Applications of cloning K: Transcription in Prokaryotes - Basic principles of transcription-- Escherichia coli RNA polymerase-- The promoter and its characterisation-- Transcription initiation, elongation and termination L: Regulation of Prokaryotic Transcription - The lac operon-- The trp operon-- Transcriptional regulation by alternative sigma factors M. Transcription in Eukaryotes - The three polymerases, characterisation and function-- RNA pol I genes: the ribosomal repeat-- RNA pol III genes: 5S and tRNA genes-- RNA pol II genes: promoters and enhancers-- General transcription factors and Pol II initiation. N: Regulation of Transcription in Eukaryotes - Eukaryotic transcription factors-- Examples of transcriptional regulation O: RNA Processing and RNPs - rRNA processing and ribosomes-- tRNA processing, RNase P and ribozymes-- mRNA processing, hnRNPs and snRNPs-- Alternative RNA processing P: The Genetic Code and tRNA - The genetic code-- tRNA structure and function. Q: Protein Synthesis - Aspects of protein synthesis-- Mechanism of protein synthesis-- Initiation in eukaryotes-- Translational control and post translational events R: Bacteriophage and Eukaryotic Viruses - Introduction to viruses-- Bacteriophages-- DNA viruses-- RNA Viruses S: Tumour Viruses and Oncogenes - Oncogenes found in tumour viruses-- Categories of oncogenes-- Tumour suppressor genes-- Apoptosis T. Functional Genomics and New Technologies - Omics-- Genome Wide Analysis-- Cell and Molecular Imaging-- Transgenics and Stem Cell Technology U. Bioinformatics - Omics-- Bioinformatics-- Genome Wide Experiments-- Transgenics and Stem Cell Technology.
  • (source: Nielsen Book Data)9780415351676 20160528
The new edition of "Instant Notes in Molecular Biology" is an updated and revised version of a successful and well-received text. Updates include information on micro RNAs, RNAi, genome sequences, and RNA splicing. Two new sections have been included to cover functional genomics and bioinformatics in the same accessible style.
(source: Nielsen Book Data)9780415351676 20160528
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