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1 volume (various pagings) : color illustrations ; 29 cm
  • 1. Chemists and Chemistry. 2. Atoms, Molecules, and Ions. 3. Stoichiometry. 4. Types of Chemical Reactions and Solution Stoichiometry. 5. Gases. 6. Chemical Equilibrium. 7. Acids and Bases. 8. Applications of Aqueous Equilibria. 9. Energy, Enthalpy, and Thermochemistry. 10. Spontaneity, Entropy, and Free Energy. 11. Electrochemistry. 12. Quantum Mechanics and Atomic Theory. 13. Bonding: General Concepts. 14. Covalent Bonding: Orbitals. 15. Chemical Kinetics. 16. Liquids and Solids. 17. Properties of Solutions. 18. The Representative Elements. 19. Transition Metals and Coordination Chemistry. 20. The Nucleus: A Chemista (TM)s View. 21. Organic and Biochemical Molecules. Appendix 1. Mathematical Procedures. Appendix 2. Units of Measurement and Conversions Among Units. Appendix 3. Spectral Analysis. Appendix 4. Selected Thermodynamic Data. Appendix 5. Equilibrium Constants and Reduction Potentials. Appendix 6. Deriving the Integrated Rate Laws. Glossary. Answers to Selected Exercises.
  • (source: Nielsen Book Data)9781305581982 20160619
Develop the qualitative, conceptual foundation you need to think like a chemist with CHEMICAL PRINCIPLES, 8e. Designed for students with solid mathematical preparation, this best-seller emphasizes models, everyday applications of chemistry, and a thoughtful, step-by-step problem-solving approach.
(source: Nielsen Book Data)9781305581982 20160619
Chemistry & ChemEng Library (Swain)
xii, 382 pages : illustrations ; 24 cm
  • CHAPTER 1 BOND-LINE DRAWINGS 1 1.1 How to Read Bond-Line Drawings 1 1.2 How to Draw Bond-Line Drawings 5 1.3 Mistakes to Avoid 7 1.4 More Exercises 7 1.5 Identifying Formal Charges 9 1.6 Finding Lone Pairs that are Not Drawn 13 CHAPTER 2 RESONANCE 18 2.1 What is Resonance? 18 2.2 Curved Arrows: The Tools for Drawing Resonance Structures 19 2.3 The Two Commandments 21 2.4 Drawing Good Arrows 24 2.5 Formal Charges in Resonance Structures 26 2.6 Drawing Resonance Structures Step by Step 30 2.7 Drawing Resonance Structures by Recognizing Patterns 34 2.8 Assessing the Relative Importance of Resonance Structures 43 CHAPTER 3 ACID BASE REACTIONS 49 3.1 Factor 1 What Atom is the Charge On? 50 3.2 Factor 2 Resonance 53 3.3 Factor 3 Induction 56 3.4 Factor 4 Orbitals 59 3.5 Ranking the Four Factors 60 3.6 Other Factors 63 3.7 Quantitative Measurement (pKa Values) 64 3.8 Predicting the Position of Equilibrium 65 3.9 Showing a Mechanism 66 CHAPTER 4 GEOMETRY 69 4.1 Orbitals and Hybridization States 69 4.2 Geometry 72 4.3 Lone Pairs 76 CHAPTER 5 NOMENCLATURE 77 5.1 Functional Group 78 5.2 Unsaturation 80 5.3 Naming the Parent Chain 81 5.4 Naming Substituents 84 5.5 Stereoisomerism 88 5.6 Numbering 90 5.7 Common Names 95 5.8 Going from a Name to a Structure 96 CHAPTER 6 CONFORMATIONS 97 6.1 How to Draw a Newman Projection 98 6.2 Ranking the Stability of Newman Projections 102 6.3 Drawing Chair Conformations 105 6.4 Placing Groups On the Chair 108 6.5 Ring Flipping 112 6.6 Comparing the Stability of Chairs 119 6.7 Don t Be Confused by the Nomenclature 122 CHAPTER 7 CONFIGURATIONS 123 7.1 Locating Stereocenters 123 7.2 Determining the Configuration of a Stereocenter 126 7.3 Nomenclature 134 7.4 Drawing Enantiomers 138 7.5 Diastereomers 143 7.6 Meso Compounds 144 7.7 Drawing Fischer Projections 147 7.8 Optical Activity 152 CHAPTER 8 MECHANISMS 154 8.1 Introduction to Mechanisms 154 8.2 Nucleophiles and Electrophiles 154 8.3 Basicity vs. Nucleophilicity 157 8.4 Arrow-Pushing Patterns for Ionic Mechanisms 159 8.5 Carbocation Rearrangements 164 8.6 Information Contained in a Mechanism 169 CHAPTER 9 SUBSTITUTION REACTIONS 173 9.1 The Mechanisms 173 9.2 Factor 1 The Electrophile (Substrate) 175 9.3 Factor 2 The Nucleophile 178 9.4 Factor 3 The Leaving Group 180 9.5 Factor 4 The Solvent 183 9.6 Using All Four Factors 185 9.7 Substitution Reactions Teach Us Some Important Lessons 186 CHAPTER 10 ELIMINATION REACTIONS 188 10.1 The E2 Mechanism 188 10.2 The Regiochemical Outcome of an E2 Reaction 189 10.3 The Stereochemical Outcome of an E2 Reaction 191 10.4 The E1 Mechanism 194 10.5 The Regiochemical Outcome of an E1 Reaction 195 10.6 The Stereochemical Outcome of an E1 Reaction 196 10.7 Substitution vs. Elimination 196 10.8 Determining the Function of the Reagent 197 10.9 Identifying the Mechanism(s) 199 10.10 Predicting the Products 202 CHAPTER 11 ADDITION REACTIONS 206 11.1 Terminology Describing Regiochemistry 206 11.2 Terminology Describing Stereochemistry 208 11.3 Adding H and H 216 11.4 Adding H and X, Markovnikov 219 11.5 Adding H and Br, Anti-Markovnikov 226 11.6 Adding H and OH, Markovnikov 230 11.7 Adding H and OH, Anti-Markovnikov 233 11.8 Synthesis Techniques 238 11.9 Adding Br and Br-- Adding Br and OH 245 11.10 Adding OH and OH, ANTI 250 11.11 Adding OH and OH, SYN 253 11.12 Oxidative Cleavage of an Alkene 255 CHAPTER 12 ALKYNES 258 12.1 Structure and Properties of Alkynes 258 12.2 Preparation of Alkynes 261 12.3 Alkylation of Terminal Alkynes 262 12.4 Reduction of Alkynes 264 12.5 Hydration of Alkynes 268 12.6 Keto-Enol Tautomerization 273 12.7 Ozonolysis of Alkynes 278 CHAPTER 13 ALCOHOLS 280 13.1 Naming and Designating Alcohols 280 13.2 Predicting Solubility of Alcohols 281 13.3 Predicting Relative Acidity of Alcohols 283 13.4 Preparing Alcohols: A Review 286 13.5 Preparing Alcohols via Reduction 287 13.6 Preparing Alcohols via Grignard Reactions 294 13.7 Summary of Methods for Preparing Alcohols 298 13.8 Reactions of Alcohols: Substitution and Elimination 300 13.9 Reactions of Alcohols: Oxidation 303 13.10 Converting an Alcohol Into an Ether 305 CHAPTER 14 ETHERS AND EPOXIDES 308 14.1 Introduction to Ethers 308 14.2 Preparation of Ethers 310 14.3 Reactions of Ethers 313 14.4 Preparation of Epoxides 314 14.5 Ring-Opening Reactions of Epoxides 316 CHAPTER 15 SYNTHESIS 323 15.1 One-Step Syntheses 324 15.2 Multistep Syntheses 336 15.3 Retrosynthetic Analysis 337 15.4 Creating Your Own Problems 338 Answer Key 339 Index 000.
  • (source: Nielsen Book Data)9781119110668 20160704
* Helps develop the skills needed to solve a variety of problem types. * Presents the fundamental topics clearly with an informal, friendly tone. * Describes the how-to of problem solving, including approaching problems strategically. * Discusses the relationship between concepts and puts topics in context. * Covers important areas such as resonance, nomenclature, conformations, substitution reactions, synthesis and more.
(source: Nielsen Book Data)9781119110668 20160704
Chemistry & ChemEng Library (Swain)
CHEM-35-01, CHEM-35-01
x, 246 pages ; 22 cm
  • Style as choice
  • Understanding style
  • Correctness
  • Clarity
  • Actions
  • Characters
  • Cohesion and coherence
  • Emphasis
  • Clarity of form
  • Motivation
  • Global coherence
  • Grace
  • Concision
  • Shape --Elegance
  • Ethics
  • The ethics of style.
Chemistry & ChemEng Library (Swain)
xii, 1161 pages : illustrations ; 29 cm
Chemistry & ChemEng Library (Swain)
lxiii, 964 pages : illustrations ; 25 cm + 1 DVD-ROM (4 3/4 in.)
Advances in Industrial Mixing is a companion volume and update to the Handbook of Industrial Mixing. The second volume fills in gaps for a number of industries that were not covered in the first edition. Significant changes in five of the fundamental areas are covered in entirely updated or new chapters. The original text is provided as a searchable pdf file on the accompanying USB. * This book explains industrial mixers and mixing problems clearly and concisely. * Gives practical insights by the top professionals in the field, combining industrial design standards with fundamental insight. * Details applications in 14 key industries. Six of these are new since the first edition. * Provides the professional with information he/she did not receive in school. * Five completely rewritten chapters on mixing fundamentals where significant advances have happened since the first edition and seven concise update chapters which summarize critical technical information.
(source: Nielsen Book Data)9780470523827 20160619
Chemistry & ChemEng Library (Swain)
xxiv, 652 pages : illustrations ; 29 cm + 1 CD-ROM (4 3/4 in.)
A comprehensive study of analytical chemistry providing the basics of analytical chemistry and introductions to the laboratory * Covers the basics of a chemistry lab including lab safety, glassware, and common instrumentation * Covers fundamentals of analytical techniques such as wet chemistry, instrumental analyses, spectroscopy, chromatography, FTIR, NMR, XRF, XRD, HPLC, GC-MS, Capillary Electrophoresis, and proteomics * Includes ChemTech an interactive program that contains lesson exercises, useful calculators and an interactive periodic table * Details Laboratory Information Management System a program used to log in samples, input data, search samples, approve samples, and print reports and certificates of analysis.
(source: Nielsen Book Data)9781118714843 20160619
Chemistry & ChemEng Library (Swain)
2 volumes : illustrations ; 26 cm.
Chemistry & ChemEng Library (Swain)
2 volumes : illustrations ; 26 cm.
  • Volume 1. Polyene cyclizations
  • Cation-pi cyclizations of epoxides and polyepoxides
  • Metathesis reactions
  • Enyne-metathesis-based domino reactions in natural product synthesis
  • Domino metathesis reactions involving carbonyls
  • Radical reactions
  • Peroxy radical additions
  • Radical cyclizations
  • Tandem radical processes
  • Non-radical skeletal rearrangements
  • Protic acid/base induced reactions
  • Lewis acid/base induced reations
  • Brook rearrangement as the key step in domino reactions
  • Metal-mediated reactions
  • Palladium-mediated domino-reactions
  • Dirhodium-catalyzed domino reactions
  • Gold-mediated reactions
  • Rare earth metal mediated domino reactions
  • Cobalt and other metal mediated domino reactions: the Pauson-Khand reaction and its use in natural product total synthesis.
  • Volume 2. Pericyclic reactions
  • The Diels-Alder cycloaddition reaction in the context of domino processes
  • Domino reactions including [2+2], [3+2], or [5+2] cycloadditions
  • Domino transformations involving an electrocyclization reaction
  • Sigmatropic shifts and Ene reactions (excluding [3,3])
  • Domino transformations initiated by of proceeding through [3,3]-sigmatropic rearrangements
  • Intermolecular alkylative dearomatization of phenolic derivatives in organic synthesis
  • Additions to alkenes and C=O and C=N bonds
  • Additions to nonactivated C=C bonds.
Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds.
Chemistry & ChemEng Library (Swain)
304 p. ill. 24 x 16 cm
Chemistry & ChemEng Library (Swain)
xix, 545 pages : illustrations ; 25 cm
  • Differential Equations Introduction ODE Model Development References First-Order Ordinary Differential Equations Linear Equations Additional Information on Linear Equations Nonlinear Equations Problem Setup Problems References Linear Second-Order and Systems of First-Order Ordinary Differential Equations Introduction Fundamental Solutions of Homogeneous Equations Homogeneous Equations with Constant Coefficients Nonhomogeneous Equations Variable Coefficient Problems Alternative Methods Applications of Second-Order Differential Equations Systems of First-Order Ordinary Differential Equations Problems References Sturm-Liouville Problems Introduction Classification of Sturm-Liouville Problems Eigenfunction Expansion Problems References Fourier Series and Integrals Introduction Fourier Coefficients Arbitrary Interval Cosine and Sine Series Convergence of Fourier Series Fourier Integrals Problems References Partial Differential Equations Introduction Separation of Variables Nonhomogeneous Problem and Eigenfunction Expansion Laplace Transform Methods Combination of Variables Fourier Integral Methods Regular Perturbation Approaches Problems References Applications of Partial Differential Equations in Chemical Engineering Introduction Heat Transfer Mass Transfer Comparison between Heat and Mass Transfer Results Simultaneous Diffusion and Convection Simultaneous Diffusion and Chemical Reaction Simultaneous Diffusion, Convection, and Chemical Reaction Viscous Flow Problems References Dimensional Analysis and Scaling of Boundary Value Problems Introduction Classical Approach to Dimensional Analysis Finding the PIs Scaling Boundary Value Problems Problems References Selected Numerical Methods and Available Software Packages Introduction and Philosophy Solution of Nonlinear Algebraic Equations Solution of Simultaneous Linear Algebraic Equations Solution of Ordinary Differential Equations Numerical Solution of Partial Differential Equations Summary Problems References Appendices Elementary Properties of Determinants and Matrices Numerical Method of Lines Example Using MATLAB(R) Program for a Transport and Binding Kinetics Model of an Analyte Programmed Model of a Drug Delivery System.
  • (source: Nielsen Book Data)9781466552999 20160619
Focusing on the application of mathematics to chemical engineering, Applied Mathematical Methods for Chemical Engineers addresses the setup and verification of mathematical models using experimental or other independently derived data. The book provides an introduction to differential equations common to chemical engineering, followed by examples of first-order and linear second-order ordinary differential equations. Later chapters examine Sturm-Liouville problems, Fourier series, integrals, linear partial differential equations, regular perturbation, combination of variables, and numerical methods emphasizing the method of lines with MATLAB(R) programming examples. Fully revised and updated, this Third Edition: * Includes additional examples related to process control, Bessel Functions, and contemporary areas such as drug delivery * Introduces examples of variable coefficient Sturm-Liouville problems both in the regular and singular types * Demonstrates the use of Euler and modified Euler methods alongside the Runge-Kutta order-four method * Inserts more depth on specific applications such as nonhomogeneous cases of separation of variables * Adds a section on special types of matrices such as upper- and lower-triangular matrices * Presents a justification for Fourier-Bessel series in preference to a complicated proof * Incorporates examples related to biomedical engineering applications * Illustrates the use of the predictor-corrector method * Expands the problem sets of numerous chapters Applied Mathematical Methods for Chemical Engineers, Third Edition uses worked examples to expose several mathematical methods that are essential to solving real-world process engineering problems.
(source: Nielsen Book Data)9781466552999 20160619
Chemistry & ChemEng Library (Swain)
xii, 604 pages, 24 unnumbered pages of plates : illustrations (some color), maps (some color) ; 25 cm
Chemistry & ChemEng Library (Swain)
xxiii, 463 pages : illustrations ; 25 cm
A timely, accessible survey of the multidisciplinary field of bioanalytical chemistry * Provides an all in one approach for both beginners and experts, from a broad range of backgrounds, covering introductions, theory, advanced concepts and diverse applications for each method * Each chapter progresses from basic concepts to applications involving real samples * Includes three new chapters on Biomimetic Materials, Lab-on-Chip, and Analytical Methods * Contains end-of-chapter problems and an appendix with selected answers.
(source: Nielsen Book Data)9781118302545 20160619
Chemistry & ChemEng Library (Swain)
1 volume (various pagings) : color illustrations ; 29 cm
  • 1 Biochemistry and the Language of Chemistry 2 The Chemical Foundation of Life: Weak Interactions in an Aqueous Environment 3 The Energetics of Life 4 Nucleic Acids 5 Introduction to Proteins: The Primary Level of Protein Structure 6 The Three-Dimensional Structure of Proteins 7 Protein Function and Evolution 8 Enzymes: Biological Catalysts 9 Carbohydrates: Sugars, Saccharides, Glycans 10 Lipids, Membranes, and Cellular Transport 11 Chemical Logic of Metabolism 12 Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway 13 The Citric Acid Cycle 14 Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism 15 Photosynthesis 16 Lipid Metabolism 17 Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates 18 Amino Acid and Nitrogen Metabolism 19 Nucleotide Metabolism 20 Mechanisms of Signal Transduction 21 Genes, Genomes, and Chromosomes 22 DNA Replication 23 DNA Repair, Recombination, and Rearrangement 24 Transcription and Post-transcriptional Processing 25 Information Decoding: Translation and Post-translational Protein Processing 26 Regulation of Gene Expression.
  • (source: Nielsen Book Data)9780321839763 20160618
NOTE: Before purchasing, check with your instructor to ensure you select the correct ISBN. Several versions of Pearson's MyLab & Mastering products exist for each title, and registrations are not transferable. To register for and use Pearson's MyLab & Mastering products, you may also need a Course ID, which your instructor will provide. Used books, rentals, and purchases made outside of Pearson If purchasing or renting from companies other than Pearson, the access codes for Pearson's MyLab & Mastering products may not be included, may be incorrect, or may be previously redeemed. Check with the seller before completing your purchase. For one or two semester biochemistry courses (science majors). This package includes MasteringChemistry(R). A highly visual, precise and fresh approach to guide today's mixed-science majors to a deeper understanding of biochemistry Biochemistry: Concepts and Connections engages students in the rapidly evolving field of biochemistry, better preparing them for the challenges of 21st century science through quantitative reasoning skills and a rich, chemical perspective on biological processes. This concise first edition teaches mixed-science-majors the chemical logic underlying the mechanisms, pathways, and processes in living cells through groundbreaking biochemical art and a clear narrative that illustrates biochemistry's relation to all other life sciences. Integration of biochemistry's experimental underpinnings alongside the presentation of modern techniques encourages students to appreciate and consider how their understanding of biochemistry can and will contribute to solving problems in medicine, agricultural sciences, environmental sciences, and forensics. The text is fully integrated with MasteringChemistry to provide support for students before, during, and after class. Highlights include interactive animations and tutorials based on the textbook's biochemical art program and Foundation Figures to help students visualize complex processes, apply, and test conceptual understanding as well as quantitative reasoning. Superior support beyond the classroom with MasteringChemistry MasteringChemistry from Pearson is the leading online homework, tutorial, and assessment system, designed to improve results by engaging students before, during, and after class with powerful content. Instructors ensure students arrive prepared by assigning interaction with relevant biochemical concepts before class, and encourage critical thinking, visualization, and retention with in-class resources such as Learning CatalyticsTM. Students can further master concepts after class by interacting with biochemistry animations, problem sets, and tutorial assignments that provide hints and answer-specific feedback. The Mastering gradebook records scores for all automatically graded assignments in one place, while diagnostic tools give instructors access to rich data to assess student understanding and misconceptions. Mastering brings learning full circle by continuously adapting to each student and making learning more personal than ever-before, during, and after class. 0321839765 / 9780321839763 Biochemistry: Concepts and Connections Plus MasteringChemistry with eText -- Access Card Package Package consists of: 0133871975 / 9780133871975 MasteringChemistry with Pearson eText -- ValuePack Access -- for Biochemistry: Concepts and Connections 0321839927 / 9780321839923 Biochemistry: Concepts and Connections.
(source: Nielsen Book Data)9780321839763 20160618
Biology Library (Falconer), Chemistry & ChemEng Library (Swain)
xv, 364 pages : illustrations ; 24 cm
  • Preface Section 1: Biohydrogen Production Thermophilic Biohydrogen Production: Challenges at the Industrial Scale-- Sudhir Kumar, Aditya Bhalla, Mohit Bibra, Jia Wang, Kayla Morisette, Subramanian M. Raj, David Salem, and Rajesh K. Sani Bio-hydrogen Production: Current Trends and Future Prospects-- Vinita Mishra and Isha Srivastava Section 2: Microbial Fuel Cells Microbial Fuel Cells: A Promising Alternative Energy Source-- M. J. Angelaa Lincy, B. Ashokkumar, M. Vasantha, and P. Varalakshmi Challenges to and Opportunities in Microbial Fuel Cells-- J. Jayapriya and V. Ramamurthy Systems Biology Approaches for Microbial Fuel Cell Applications-- Navanietha Krishnaraj. R, and Jong-Sung Yu Section 3: Bioethanol Production Potentials of Oscillatoria annae in Producing Bioethanol by Degradation of Selected Lignocellulosics-- P.Malliga, V. Viswajith, D. Malini, and R. Sabitha Challenges in Harnessing the Potential of Lignocellulosic Biofuels and the Probable Combating Strategies-- Lakshmi Shri Roy, Vijay Kumar Garlapati, and Rintu Banerjee Section 4: Biodesel Production Biodiesel: Production, Opportunities and Challenges-- Deeksha An Overview Of Reactor Designs for Biodesel Production-- Vijay Kumar Garlapati, Lakshmi Shri Roy, and Rintu Banerjee Studies on the Effect of Antioxidants on the Long-Term Storage Stability and Oxidation Stability of Pongamia pinnata and Jatropha curcus Biodiesel-- A. Obadiah and S. Vasanth Kumar Effect of Fungal Biotic Stress on Physic Nut (Jatropha curcas L.)-- Seweta Srivastava and Asha Sinhda Section 5: Catalysis for Biofuels A Chemist's Perspective on Bioenergy: Opportunities and Challenges-- Sannapaneni Janardan, B. B. Pavankumar, Shivendu Ranjan, Nandita Dasguptand, Melvin Samuel, Chidambaram Ramalingam, Akella Sivaramakrishna, and Kari Vijayakrishna Index.
  • (source: Nielsen Book Data)9781771881098 20160619
Energy is one of the prime needs of the modern world, and energy demands have been rapidly increasing in the recent years owing to rapid advancements in industrialization and population explosion. Conventional fossil fuels are being depleted at rapid rates, and the use of conventional sources such as coal or nuclear sources cause several hazards to the environment. New sources of fuel, such as bioenergy, are an ideal option for fulfilling ever-increasing energy demands. This important book offers an exploration of these alternate fuel sources, including biohydrogen, microbial fuel cells, bioethanol, and biodiesel production, focusing on the challenges and factors hindering the real-time application of these bioenergy sources. Researchers all over the world are working in this energy sector, and this has led to drastic improvements in bioenergy research. However, the technology gap between research and industrial application still exists. This important book offers engineers and technologists from different disciplines valuable information on this multifaceted field. The field of bioenergy is interdisciplinary, requiring the knowledge of biologists, chemists, physicists, and engineers. Exploring the current trends and future prospects for biofuels, the information presented in this book will be valuable to the international industrial community for identifying new options to circumvent problems that exist in bioenergy applications. Topics include: * Thermophilic biohydrogen production * Bio-hydrogen production * Microbial fuel cells as a promising alternative energy source * Microbial fuel cell applications * Potential of Pscillatoria annae in producing bioethanol * Potential of lignocellulosic biofuels * Biodiesel production * Reactor designs for biodesel production * Long-term storage stability of Pongamia pinnata and Jatropha curcus biodiesel.
(source: Nielsen Book Data)9781771881098 20160619
Chemistry & ChemEng Library (Swain)
xi, 233 pages, 8 unnumbered pages of plates : illustrations (some color) ; 26 cm
  • Foreword-- Preface: the future of drug discovery and health care Eric Schadt-- 1. The art and science of the Drug Discovery Pipeline (DDP) William T. Loging-- 2. Computational approaches to drug target identification Thomas B. Freeman and Pek Lum-- 3. Understanding human disease knowledge through text mining Raul Rodriguez-Esteban-- 4. Integrating translational biomarkers into drug development Jonathan Phillips-- 5. Computational phenotypic assessment of small molecules in drug discovery William T. Loging and Thomas B. Freeman-- 6. Data visualization and the DDP process Ke Xu-- 7. Information visualization - important IT considerations Telmo Silva-- 8. The New Drug Application (NDA) and regulatory approval stages William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield-- 9. Clinical trial failures and drug repositioning Mark Crawford and Jeff Handler-- Appendix I. Additional knowledge-based analysis approaches Raul Rodriguez-Esteban-- Appendix II. Open source tools and public data sources Yirong Wang and William T. Loging-- Index.
  • (source: Nielsen Book Data)9780521768009 20160711
Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline. Additionally, a focus section provides innovative visualisation approaches, from both the drug discovery process as well as from other fields that utilise large datasets, recognising the increasing use of such technology. Serving the needs of early career and more experienced scientists, this up-to-date reference provides an essential introduction to the process and background of drug discovery, highlighting how computational researchers can contribute to that pipeline.
(source: Nielsen Book Data)9780521768009 20160711
Chemistry & ChemEng Library (Swain)
xvii, 426 pages : illustrations (some color) ; 24 cm
  • Preface Editor Contributors Nanomaterials for Drug Delivery Stimuli-Responsive Nanostructured Silica Matrix Targeting Drug Delivery Applications Sanghoon Kim, Nadia Canilho, and Andreea Pasc Gold Nanoparticles: A Novel and Promising Avenue for Drug Delivery Shuaidong Huo, Xin Cao, Zhongbo Hu, and Xing-lie Liang Liposomes as a Drug Delivery System Kacoli Banerjee, Shubhadeep Banerjee, and Mahitosh Mandai Nanocarriers for Breast Cancer Therapeutics Deepti Rana, Shylaja Arulkumar, Akshayaa Ganesh, and Murugan Ramalingam Nanoparticles as a Promise for Host Defense Peptide Therapeutics Carlos Lopez-Abarrategui, Anselmo J. Otero-Gonzalez, Annia Alba-Menendez, Edilso Reguera, and Octavio Luiz Franco Novel Nanostructured Bioactive Restorative Materials for Dental Applications Mary Anne S. Melo, Lei Cheng, Ke Zhang, Michael D. Weir, Xuedong Zhou, Yuxing Bai, Lidiany K.A. Rodrigues, and Hockin H.K. Xu Redox-Triggered, Biocompatible, Inorganic Nanoplatforms for Cancer Theranostics Xin-Chun Huang, Yun-Ling Luo, and Hsin-Yun Hsu Antimicrobial Nanomaterials Surface Characteristics Dictate Microbial Adhesion Ability Klemen Bohinc, Mojca Jevsnik, Rok Fink, Goran Drazic, and Peter Raspor Antimicrobial Polymers Based on Nanostructures: A New Generation of Materials with Medical Applications Maria Isabel Gonzalez-Sanchez, Stefano Perni, and Polina Prokopovich Nanomaterials in Biosensors Recent Advances in Nanodiagnostic Techniques for Infectious Agents Muhammad Ali Syed Chromogenic Biosensors for Pathogen Detection Alok P. Das, B. Bal, and P.S. Mahapatra Electrochemical Biosensors for Detecting DNA Damage and Genotoxicity Ali A. Ensafi and Esmaeil Heydari-Bafrooei In Vivo Molecular Imaging with Quantum Dots: Toward Multimodality and Theranostics Sarah P. Yang, Shreya Goel, and Weibo Cai Surface Modifications by Polymers for Biosensing Applications Laura Sola, Chiara Finetti, Paola Gagni, Marcella Chiari, and Marina Cretich Safety of Nanomaterials Nanotoxicity: A Mechanistic Approach Indarchand Gupta, Swapnil Gaikwad, Avinash Ingle, Kateryna Kon, Nelson Duran, and Mahendra Rai Index.
  • (source: Nielsen Book Data)9781482250169 20160619
Biological and Pharmaceutical Applications of Nanomaterials presents the findings of cutting-edge research activities in the field of nanomaterials, with a particular emphasis on biological and pharmaceutical applications. Divided into four sections-nanomaterials for drug delivery, antimicrobial nanomaterials, nanomaterials in biosensors, and safety of nanomaterials-this book: * Covers topics such as stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for targeting drug delivery and dental applications * Describes the use of nanocarriers and nanoparticles as cancer and peptide therapeutics, the influence of surface characteristics on microbial adhesion, and the latest developments in antimicrobial nanostructured polymers for medical applications * Discusses recent advances in nanodiagnostic techniques for infectious agents, chromogenic biosensors for pathogen detection, electrochemical biosensors for detecting DNA damage and genotoxicity, and molecular imaging with quantum dots including surface modifications by polymers for biosensing applications Featuring contributions from field experts and researchers in industry and academia, Biological and Pharmaceutical Applications of Nanomaterials provides state-of-the-art information on nanomaterials and their use in drug delivery, infection control, and biomedicine.
(source: Nielsen Book Data)9781482250169 20160619
Chemistry & ChemEng Library (Swain)
x, 399 pages : illustrations (chiefly color) ; 28 cm
  • Preface IX Preface to the 2nd edition X Introduction 1 Introduction Early developments 2 Biotechnology today 4 Microbiology Viruses 6 Bacteriophages 8 Microorganisms 10 Bacteria 12 Yeasts 14 Fungi 16 Algae 18 Some bacteria of importance for biotechnology 20 Microorganisms: isolation, preservation, safety 22 Microorganisms: strain improvement 24 Biochemistry Biochemistry 26 Amino acids, peptides, proteins 28 Enzymes: structure, function, kinetics 30 Sugars, glycosides, oligo- and polysaccharides 32 Lipids, membranes, membrane proteins 34 Metabolism 36 Genetic engineering DNA: structure 38 DNA: function 40 RNA 42 Genetic engineering: general steps 44 Preparation of DNA 46 Other useful enzymes for DNA manipulation 48 PCR: general method 50 PCR: laboratory methods 52 DNA: synthesis and size determination 54 DNA sequencing 56 Transfer of foreign DNA in living cells (transformation) 58 Gene cloning and identification 60 Gene expression 62 Gene silencing 64 Epigenetics 66 Gene libraries and gene mapping 68 Genetic maps of prokaryotes 70 Genetic maps of eukaryotes 72 Metagenomics 74 Cell biology Cell biology 76 Stem cells 78 Blood cells and immune system 80 Antibodies 82 Reporter groups 84 Solid state fermentation (SSF) 86 Growing microorganisms 88 Growth kinetics and product formation 90 Fed-batch, continuous and high cell density fermentation 92 Fermentation technology 94 Fermentation technology: scale-up 96 Cultivation of mammalian cells 98 Mammalian cell bioreactors 100 Enzyme and cell reactors 102 Recovery of bioproducts 104 Recovery of proteins: chromatography 106 Economic aspects of industrial processes 108 Food and food additives Alcoholic beverages 110 Beer 112 Fermented food 114 Food and lactic acid fermentation 116 Prebiotics and probiotics 118 Bakers yeast and fodder yeasts 120 Fodder yeasts from petroleum feedstocks, single cell oil 122 Amino acids 124 l-Glutamic acid 126 d, l-Methionine, l-lysine, and l-threonine 128 Aspartame , l-phenylalanine, and l-aspartic acid 130 Amino acids via enzymatic transformation 132 Vitamins 134 Nucleosides and nucleotides 136 Industrial products Bio-Ethanol 138 1-Butanol 140 Higher alcohols and alkenes 142 Acetic acid / vinegar 144 Citric acid 146 Lactic acid, 3-hydroxy-propionic acid (3-HP) 148 Gluconic acid and green sugar chemicals 150 Dicarboxylic acids 152 Biopolymers: Polyesters 154 Biopolymers: Polyamides 156 Polysaccharides 158 Biosurfactants 160 Fatty acids and their esters 162 Enzyme technology Biotransformation 164 Technical enzymes 166 Applied enzyme catalysis 168 Regio- and enantioselective enzymatic synthesis 170 Enzymes as processing aids 172 Detergent enzymes 174 Enzymes for starch hydrolysis 176 Enzymatic starch hydrolysis 178 Enzymes and sweeteners 180 Enzymes for the hydrolysis of cellulose and polyoses 182 Enzymes in pulp and paper processing 184 Pectinases 186 Enzymes and milk products 188 Enzymes in baking and meat processing 190 Other enzymes for food products and animal feed 192 Enzymes in leather and textile treatment 194 Procedures for obtaining novel technical enzymes 196 Protein design 198 Antibiotics Antibiotics: occurrence, applications, mechanism of action 200 Antibiotics: screening, industrial production, and mechanism of action 202 Antibiotic resistance 204 -Lactam antibiotics: structure, biosynthesis, and mechanism of action 206 -Lactam antibiotics: manufacture 208 Amino acid and peptide antibiotics 210 Glycopeptide, lipopeptide, polyether, and nucleoside anti-biotics 212 Aminoglycoside antibiotics 214 Tetracyclines, chinones, chinolones, and other aromatic antibiotics 216 Macrolide antibiotics 218 New pathways to antibiotics 220 Pharmaceuticals and medical technology Insulin 222 Growth hormone and other hormones 224 Hemoglobin, serum albumen, and lactoferrin 226 Blood clotting agents 228 Anticoagulants and thrombo-lytic agents 230 Enzyme inhibitors 232 Interferons 234 Interleukins and anti-interleukins 236 Erythropoietin and other growth factors 238 Other therapeutic proteins 240 Monoclonal and catalytic antibodies 242 Recombinant antibodies 244 Therapeutic antibodies 246 Vaccines 248 Recombinant vaccines 250 Steroid biotransformations 252 Diagnostic enzymes 254 Enzyme tests 256 Biosensors 258 Immunoanalysis 260 Glycobiology 262 Agriculture and environment Animal breeding 264 Embryo transfer, cloned animals 266 Gene maps 268 Transgenic animals 270 Breeding, gene pharming and xenotransplantation 272 Plant breeding 274 Plant tissue surface culture 276 Plant cell suspension culture 278 Transgenic plants: methods 280 Transgenic plants: resistance 282 Transgenic plants: products 284 Aerobic wastewater treatment 286 Anaerobic wastewater and sludge treatment 288 Biological treatment of exhaust air 290 Biological soil treatment 292 Microbial leaching, biofilms, and biocorrosion 294 Megatrends The human genome 296 Functional analysis of the human genome 298 Pharmacogenomics, nutrigenomics 300 DNA assays 302 Gene therapy 304 Induced pluripotent stem cells (iPS) 306 Tissue Engineering 308 Drug screening 310 High-throughput sequencing 312 Proteomics 314 DNA and protein arrays 316 Metabolic engineering 318 Synthetic biology 320 Systems biology 322 Bioinformatics: sequence and structural databases 324 Bioinformatics: functional analyses 326 Carbon sources (C-sources) 328 Biorefineries 330 Safety in genetic engineering 332 Regulation of products derived from biotechnology 334 Ethical considerations and acceptance 336 Patents in biotechnology 338 International aspects of biotechnology 340 Further Reading 343 Index 376 Picture Credits 398.
  • (source: Nielsen Book Data)9783527335152 20160718
Now presented in large format, the new Schmid is the ideal primer in biotechnology. The two-page layout with one page being a full color figure and the opposite page being explanatory text is the ideal combination between rapid visual-based learning with in depth information.
(source: Nielsen Book Data)9783527335152 20160718
Chemistry & ChemEng Library (Swain)
xxiv, 527 pages : illustrations (some color) ; 25 cm
Chemistry & ChemEng Library (Swain)
xiii, 470 pages : illustrations (some color) ; 25 cm
  • Contributors vii Preface xi 1 Carbohydrate ]Presenting Self ]Assembled Monolayers: Preparation, Analysis, and Applications in Microbiology 1 Aline Debrassi, Willem M. de Vos, Han Zuilhof, and Tom Wennekes 2 Plasmonic Methods for the Study of Carbohydrate Interactions 53 Sabine Szunerits and Rabah Boukherroub 3 Carbohydrate ]Modified Gold Nanoparticles 79 Mikkel B. Thygesen and Knud J. Jensen 4 Quantum Dot Glycoconjugates 99 Nan Li and Kagan Kerman 5 Conjugation of Glycans with Carbon Nanostructures 123 Zachary P. Michael, Alexander Star, and Sebastien Vidal 6 Synthesis of Glycopolymers and Recent Developments 137 Gokhan Yilmaz and C. Remzi Becer 7 Glycoclusters and their Applications as Anti ]Infective Agents, Vaccines, and Targeted Drug Delivery Systems 175 Juan Manuel Casas ]Solvas and Antonio Vargas ]Berenguel 8 Glyco ]Functionalized Liposomes 211 Jacob J. Weingart, Pratima Vabbilisetty, and Xue ]Long Sun 9 Glycans in Mesoporous and Nanoporous Materials 233 Keith J. Stine 10 Applications of Nanotechnology in Array ]Based Carbohydrate Analysis and Profiling 267 Jared Q. Gerlach, Michelle Kilcoyne, and Lokesh Joshi 11 Scanning Probe Microscopy for the Study of Interactions Involving Glycoproteins and Carbohydrates 285 Yih Horng Tan 12 Sialic Acid ]Modified Nanoparticles for ]Amyloid Studies 309 Hovig Kouyoumdjian and Xuefei Huang 13 Carbohydrate Nanotechnology and its Applications for the Treatment of Cancer 335 Shailesh G. Ambre and Joseph J. Barchi, Jr. 14 Carbohydrate Nanotechnology Applied to Vaccine Development 369 Rajesh Sunasee and Ravin Narain 15 Carbohydrate Nanotechnology and its Application to Biosensor Development 387 Andras Hushegyi, Ludmila Klukova, Tomas Bertok, and Jan Tkac 16 Nanotoxicology Aspects of Carbohydrate Nanostructures 423 Yinfa Ma and Qingbo Yang Index 453.
  • (source: Nielsen Book Data)9781118860533 20160619
Introducing the emerging field carbohydrate nanostructures, this book will be a unique resource for interested researchers to learn a range of methods of applying the field to their own work. Greater access, as well as greater collaboration, to this new interdisciplinary field is intended for both synthetic carbohydrate chemists and researchers in nanoscience related fields. It covers: * the main types of nanostructures presently under investigation for modification by carbohydrates, including nanoparticles, nanorods, magnetic particles, dendrimers, nanoporous, and surface confined structures * overview and introduction to the field of carbohydrate nanotechnology, and especially its applications to its biological systems * Provides a unique resource for researchers to learn about the techniques used to characterize the physical and biological properties of carbohydrate-modified nanostructures.
(source: Nielsen Book Data)9781118860533 20160619
Chemistry & ChemEng Library (Swain)
xvi, 339 pages : illustrations ; 24 cm
  • Chemical Physics. Halogen Containing Simple and Complicated Block Copolyethers. Welding Modes and Their Influence on the Adhesions. Kinetics and Mechanism of Polymer Dispersion Formation on Based of (Meth) Acrylates. Films and Nonwoven Materials Based on Polyurethane, the Styrene-Acrylonitrile Copolymer, and Their Blends. Investigation of Polypropylene/Low-Density Polyethylene Blends. Elastic Modulus of Poly(Ethylene Terephthalate)/Poly(Butylene Terephthalate) Blends. Low-Toxic Nitrogen-Containing Antioxidant for Polyvinyl Chloride. Impact of Organosilicone Modifiers on the Properties of Ethylene Copolymers. UV Spectroscopy Study of 1,2-Dihydro-C60-Fullerenes in Polar Solvent. Hexagonal Structures in Physical Chemistry and Physiology. Complex Formation Between Alk4NBr and 1,1,3-Trimethyl-3-(4-Methylphenyl)Butyl Hydroperoxide on the Base of NMR 1H Investigation. Polyamides and Polyamidoether in Macromolecules Containing Triphenylmethane Groups. A Detailed Review on Nanofibers Production and Applications. Biochemical Physics. Composition of Bioregulator Obtained from Garlic Allium Sativum L. Morphological and Bioenergetical Characteristics of Mitochondria. Halophilic Microorganisms from Saline Wastes of Starobin Potash Deposit. Biochemical Characteristics of Insects Hermetia Illucens. Peptides of a Plant Origin Exerting Hepatoprotective Properties. Index.
  • (source: Nielsen Book Data)9781771883023 20160919
Written by highly regarded experts in the field, this book covers many of the major themes of chemical and biochemical physics, addressing important issues, from concept to technology to implementation. It provides new research and updates on a variety of issues in physical chemistry and biochemical physics. Many chapters include case studies and supporting technologies and explain the conceptual thinking behind current uses and potential uses not yet implemented. By providing an applied and modern approach, this volume presents a wide-ranging view of current developments in applied methodologies in chemical and biochemical physics research.
(source: Nielsen Book Data)9781771883023 20160919
Chemistry & ChemEng Library (Swain)