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Book
1 online resource.
  • Employing 'second generation' matrices.- (MA)LDI MS mass spectrometry imaging at high specificity and sensitivity.- Techniques for fingermark analysis using MALDI MS - a practical overview.- Whole/Intact Cell MALDI MS Biotyping in Mammalian Cell Analyis.- MALDI biotyping for microorganism identification in clinical microbiology.- Future applications of MALDI-TOF MS in microbiology.- MALDESI: Fundamentals, direct analysis, and MS imaging.- Microprobe MS Imaging of Live Tissues, Cells, and Bacterial Colonies using LAESI.- Efficient production of multiply charged MALDI ions.- Food Authentication by MALDI MS - MALDI-TOF MS Analysis of Fish Species.- Quantitative MALDI MS using Ionic Liquid Matrices.- Disease profiling by MALDI MS analysis of biofluids.- Ionic Liquids and other liquid matrices for sensitive MALDI MS analysis.- Coupling liquid MALDI MS to liquid chromatography.
  • (source: Nielsen Book Data)
This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: * Showcases new techniques and applications in MALDI MS * Demonstrates how MALDI is preferable to ESI (electrospray ionization) * Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics.
(source: Nielsen Book Data)
Book
1 online resource.
Book
115 pages : illustrations ; 23 cm
A volume in the Emerging Issues in Analytical Chemistry series, published in partnership with RTI International and edited by Brian F. Thomas, The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations provides analytical chemistry methods that address the latest issues surrounding cannabis-based products. The plethora of marketed strains of cannabis and cannabinoid-containing products, combined with the lack of industry standards and labelling requirements, adds to the general perception of poor quality control and limited product oversight. The methods described in this leading-edge volume help to support the manufacturing, labelling, and distribution of safe and consistent products with known chemical content and demonstrated performance characteristics. It treats analytical chemistry within the context of the diverse issues surrounding medicinal and recreational cannabis in a manner designed to foster understanding and rational perspective in non-scientist stakeholders as well as scientists who are concerned with bringing a necessary degree of order to a field now characterized by confusion and contradiction. * Addresses current and emerging analytical chemistry methods-an approach that is unique among the literature on this topic* Presents information from a broad perspective of the issues in a single compact volume* Employs language comprehensible to non-technical stakeholders as well as to specialists in analytical chemistry.
(source: Nielsen Book Data)
Biology Library (Falconer)
Book
1 online resource (5 volumes) : illustrations (some color)
  • Volume 1. Liquid chromatography
  • volume 2. Special liquid chromatography modes and capillary electromigration techniques
  • volume 3. Gas, supercritical and chiral chromatography
  • volume 4. Chromatographic and related techniques
  • volume 5. Sample treatment, method validation, and applications.
Book
1 online resource (viii, 336 pages) : illustrations (some color)
In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microbial characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microbial identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microbial characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microbial identification have been deployed worldwide in hospitals and clinical labs. While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In thirteen individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools. The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.

6. Calorimetry [2016]

Book
online resource (xix, 493 pages) : illustrations (chiefly color).
Medical Library (Lane)
Book
1 online resource (XVI, 243 p.) : online resource. Digital: text file; PDF.
  • 1 - Underneath the Pantanal Wetland: a Deep-time History of Gondwana Assembly, Climate Change, and the Dawn of Metazoan Life (LV Warren*, F Quaglio, M G Simoes, BT Freitas, ML Assine and C Ricommini) 2 - Geology and Geomorphology of the Pantanal Basin (ML Assine*, A Silva, FN Pupim, ER Merino and D Mendes) 3 - Paleolimnology in the Pantanal: Using Lake Sediment Archives to Track Late Quaternary Environmental Change in the World's Largest Neotropical Wetland (MM McGlue*, A Silva, ML Assine, JC Stevaux and FW Cruz) 4 - Changing Rivers and the Hydrology of the Pantanal Wetland (ML Assine*, JC Stevaux, HA Macedo, I Bergier, C Padovani, and A Silva) *Corresponding author: "Mario L. Assine" 5 - Terrestrial and Aquatic Vegetation Diversity of the Pantanal Wetland (A Pott* and JSV Silva) 6 - Metabolic Scaling Applied to Native Woody Savanna Species in the Pantanal of Nhecolandia (I Bergier, SM Salis*, and PP Mattos) 7 - Alkaline Lakes Dynamics in the Nhecolandia Landscape (I Bergier*, A Krusche and F Guerin) 8 - Methane and Carbon Dioxide Emissions from the Paraguay River floodplain (Pantanal) during Episodic Anoxia Events (I Bergier*, APS Silva, H Monteiro, F Guerin, HA Macedo, A Silva, A Krusche, HO Sawakuchi and D Bastviken) 9 - Pesticides in the Pantanal (E Dores) 10 - Historical Land-use Changes in Sao Gabriel do Oeste at the Upper Taquari River Basin (LS Buller*, GB Silva, MR Zanetti, E Ortega, A Moraes, T Goulart and I Bergier) 11 - Natural and Environmental Vulnerability along the Touristic "Estradas Parque Pantanal" by GIS Algebraic Mapping (GH Cavazzana, G Lastoria, KF Roche, TGT Catalini and AC Paranhos Filho) 12 - Climate Change Scenarios in the Pantanal (J Marengo*, G Sampaio and LM Alves).
  • (source: Nielsen Book Data)
This book provides readers with in-depth insights into the changes in the Pantanal wetland from its formation to the actual and likely future states. It reveals that today's Pantanal is an evolutionary consequence of geological, ecological and, more recently, man-made events taking place at distinct space-time intervals. Topics include geotectonics and sun-earth interactions, which largely dictate the rate of drastic changes that eventually disrupt ecological stability and radically rebuild the regional landscape. Furthermore, the biota-climate system is discussed as a major driver reshaping the ecohydrology functioning of the landscape on an intermediate timescale. Also covered are major changes in the landscape ecohydrology and biodiversity due to recent land-use and climate changes induced by humankind in the Anthropocene. The ability to recognize how those temporal scales impact the Pantanal wetland provides the opportunity for wise management approaches and the sustainable development of the region.
(source: Nielsen Book Data)
Book
1 online resource (xiv, 220 p.) : ill. (some col.). Digital: text file; PDF.
  • Introduction on emerging contaminants in rivers and their environmental risk.- Contaminants of emerging concern in Mediterranean watersheds.- Emerging organic contaminants in aquifers: Sources, transport, fate, and attenuation.- Effects of emerging contaminants on biodiversity, community structure, and adaptation of river biota.- Bioaccumulation of emerging contaminants in the biota: patterns in Mediterranean river networks.- Ecosystem responses to emerging contaminants: fate and effects of pharmaceuticals in a Mediterranean river.- Fate and degradation of emerging contaminants in rivers: Models review.- The emerging contaminants in the context of the EU Water Framework Directive.
  • (source: Nielsen Book Data)
This volume offers an overview of the occurrence of emerging organic contaminants in Mediterranean rivers and their relevance to their chemical and ecological quality under water scarcity. With chapters covering the effects under multiple stress conditions of pharmaceuticals, polar pesticides, personal care products, and industrial chemicals, the observations presented can be applicable to other parts of the world where water scarcity is an issue . It is of interest to environmental chemists, ecologists, environmental engineers, and ecotoxicologists, as well as water managers and decision-makers.
(source: Nielsen Book Data)
Book
1 online resource (xiv, 263 p.) : ill. (some col.). Digital: text file; PDF.
  • Part I: Solar and Wind Energy Recursive Estimation Methods to Forecast Short-Term Solar Irradiation A. Martin, Juan R. Trapero Technical and environmental analysis of parabolic trough Concentrating Solar Power (CSP) technologies G. San Miguel, B. Corona, J. Servert, D. Lopez, E. Cerrajero, F. Gutierrez, M. Lasheras Wind power forecast error probabilistic model using Markov Chains S. Martin Martinez, A. Honrubia Escribano, M. Canas Carreton, V. Guerrero Mestre and E. Gomez Lazaro Part II: Energy Storage Energy Storage Integration with Renewable Energies: the Case of Concentration Photovoltaic Systems Carlos de la Cruz, Monica Baptista Lema, Xavier del Toro Garcia, Pedro Roncero-Sanchez Batteries and Ultracapacitors based Energy Storage in Renewable Multi-Sources Systems Mahamadou Abdou Tankari, Gilles Lefebvre Different Phase Change Materials Implementations for Thermal Energy Storage Mustapha Karkri, Gilles Lefebvre, Laurent Royon Part III: Biomass Bio-refineries: an Overview on Bio-Ethanol Production Juan Carlos Dominguez Toribio, Francisco Jesus Fernandez Morales Effects of External Resistance on Microbial Fuel Cell's Performance A. Gonzalez del Campo, P. Canizares, J. Lobatob, M. Rodrigo, F.J. Fernandez The avocado and its waste: an approach of fuel potential/application Maria Paz Dominguez-- Karina Araus-- Pamela Bonert-- Francisco Sanchez-- Guillermo San Miguel-- Mario Toledo Part IV: Socio-economy of Energy Agency and Learning Relationships Against Energy Efficiency Barriers Martin Rubio, I., Florence Sandoval, A., Gonzalez Sanchez, E.
  • (source: Nielsen Book Data)
This volume provides a comprehensive overview of advanced research in the field of efficient, clean and renewable energy production, conversion and storage. The ten chapters, written by internationally respected experts, address the following topics: (1) solar and wind energy; (2) energy storage in batteries; (3) biomass; and (4) socio-economic aspects of energy. Given its multidisciplinary approach, which combines environmental analysis and an engineering perspective, the book offers a valuable resource for all researchers and students interested in environmentally sustainable energy production, conversion, storage and its engineering.
(source: Nielsen Book Data)
Book
1 online resource
Book
1 online resource.
  • Part I General issues.- Characteristic and specificity of trace analysis.- Quality evaluation of analytical results - errors classification, uncertainty estimation.- Calibration problems in trace analysis.- Certified reference materials in trace analysis.- Wet decomposition methods in inorganic trace elemental analysis.- Extraction methods in trace analysis.- Part II Application.- Trace analysis of selected organic compounds.- Analysis of drugs impurities.- Elemental analysis of food products.- Trace analysis for Metabolomics and metabonomics.- Determination of selected drugs and their metabolites in biological fluids.- Forensics I: Analytical methods in examination of forensic traces.- Forensics II: Micro traces in clinical and forensic toxicology.- Part III Special aspects.- Inorganic and bioinorganic speciation analysis - selected problems.- Quantification of platinum metals in biological and environmental samples.- Determination of volatile organic compounds by hyphenated chromatographic techniques.- Analysis of radionuclides.
  • (source: Nielsen Book Data)
This handbook is unique in its comprehensive coverage of the subject and focus on practical applications in diverse fields. It includes methods for sample preparation, the role of certified reference materials, calibration methods and statistical evaluation of the results. Problems concerning inorganic and bioinorganic speciation analysis, as well as special aspects such as trace analysis of noble metals, radionuclides and volatile organic compounds are also discussed. A significant part of the content presents applications of methods and procedures in medicine (metabolomics and therapeutic drug monitoring); pharmacy (the analysis of contaminants in drugs); studies of environmental samples; food samples and forensic analytics - essential examples that will also facilitate problem solving in related areas.
(source: Nielsen Book Data)
Book
1 online resource (xii, 571 pages) : illustrations (some color).
  • Overview.- Early Work and SSRP.- Instrumentation and Spin Resolved.- Theory.- Inelastic Mean Free Path.- Final State Effects.- Recoil Effects.- Atomic and Molecular.- Angle Resolved.- Valence Density of States.- Diffraction.- Advanced Materials.- Correlated Materials.- Perovskite Interfaces and Superlattices.- Heusler Compounds.- In-Situ Surface Chemistry.- Heterojunction Band Alignment.- Semiconductor Electronics.- Photoelectron Imaging.- Time Resolved.
  • (source: Nielsen Book Data)
This book provides the first complete and up-to-date summary of the state of the art in HAXPES and motivates readers to harness its powerful capabilities in their own research. The chapters are written by experts. They include historical work, modern instrumentation, theory and applications. This book spans from physics to chemistry and materials science and engineering. In consideration of the rapid development of the technique, several chapters include highlights illustrating future opportunities as well.
(source: Nielsen Book Data)
Book
1 online resource.
An Agilent 400-MR nuclear magnetic resonance (NMR) spectrometer and ancillary equipment were purchased, which are being used for molecular structure elucidation. The instrumentation is housed in a pre-existing facility designed specifically for its use. This instrument package is being used to expand the research and educational efforts of the faculty and students at SUNY-Geneseo and is made available to neighboring educational institutions and business concerns. Funds were also used for training of College personnel, maintenance of the instrumentation, and installation of the equipment.
Book
1 online resource.
  • Front Cover; Molecularly Imprinted Catalysts; Copyright; Contents; Contributors; Editors' Biographies; Foreword; Preface; 1
  • Molecularly Imprinted Polymers for Enzyme-like Catalysis: Principle, Design, and Applications; 1. Introduction; 2. Generic Profile of Molecular Imprinting; 3. Rationally Optimized Interactions within Imprinted Polymers; 4. Some Basic Issues in Imprinted Polymer Catalysts for Selective Catalysis; 5. Molecular Imprinting with Transition State Analogues as the Template; 6. Molecular Imprinting with Substrate as the Template
  • 7. Molecular Imprinting with Product as the Template8. Future Outlook of Molecular Imprinting in Catalysis; 9. Concluding Remarks; Acknowledgments; References; 2
  • Catalytically Active MIP Architectures; 1. Introduction; 2. Transition State Analogues as Templates in Abzyme Mimics; 3. Metal Complexes and Prosthetic Groups in Enzyme Mimics; 4. MIP-Enzyme Architectures; 5. Protein-Based MIPs; 6. Summary and Outlook; References; 3
  • Molecularly Imprinted Catalysts: Synthesis and Applications; 1. Introduction; 2. Design of MIPs for Catalytic Action
  • 3. Different Designs of MIPs for the Biomimetic Catalyst3.1 MIPs as Mimics of Hydrolytic Enzyme; 3.1.1 Ester Hydrolysis; 3.1.2 Stereoselective Hydrolysis; 3.1.3 Charged Hydrogen Bonding and Ester Hydrolysis; 3.1.4 Carbonate and Carbamate Hydrolysis; 3.1.5 Cellulose Hydrolysis; 3.2 MIP with Cholesterol Esterase Activity; 3.3 MIP Catalyst-Enhanced Elimination Reaction; 3.4 Diels-Alder Catalysis; 3.5 Metalloenzyme-Based MIP Catalysts; 3.6 MIP Catalyst for Isomerization Reactions; 4. Recent Progress Made in MIPs to Enhance Their Biomimetic Catalyst Property
  • 4.1 Intrinsic Factors for Enhancement of Biomimetic Catalyst Property4.1.1 High Enzyme Substrate Binding Affinities; 4.1.2 High Synergy between Recognition and Catalysis; 4.1.3 High Catalytic Turnover; 4.1.4 Substantial Rate Accelerations; 4.2 Extrinsic Factors for Enhancement of Biomimetic Catalyst Property; 4.2.1 Development of Computational Methodology Affiliated with MIPs as Biomimetic Catalyst; 5. Conclusion; References; 4
  • Advances and Challenges in the Design and Synthesis of Molecularly Imprinted Microspheres; 1. Introduction
  • 2. Progress in Design and Synthesis of Molecularly Imprinted Microspheres2.1 Methods of Initiation; 2.1.1 Controlled Radical Polymerization; 2.1.2 Iniferters; 2.1.3 Nitroxide-Mediated Polymerization; 2.1.4 Reversible Addition Fragmentation Polymerization; 2.1.5 Atom Transfer Radical Polymerization; 2.1.6 Porogens; 2.2 Cross-linkers and Functional Monomers; 2.3 Other Strategies; 3. Challenges in the Design and Synthesis of Molecularly Imprinted Microspheres; 4. Future Outlook: Processable Star MIPs; 5. Conclusion; References
  • 5
  • Molecularly Imprinted Polymers: Principle, Design, and Enzyme-Like Catalysis
Molecularly Imprinted Catalysts: Principle, Synthesis, and Applications is the first book of its kind to provide an in-depth overview of molecularly imprinted catalysts and selective catalysis, including technical details, principles of selective catalysis, preparation processes, the catalytically active polymers themselves, and important progress made in this field. It serves as an important reference for scientists, students, and researchers who are working in the areas of molecular imprinting, catalysis, molecular recognition, materials science, biotechnology, and nanotechnology.Comprising a diverse group of experts from prestigious universities and industries across the world, the contributors to this book provide access to the latest knowledge and eye-catching achievements in the field, and an understanding of what progress has been made and to what extent it is being advanced in industry.The first book in the field on molecularly imprinted catalysts (MIPs)Provides a systematic background to selective catalysis, especially the basic concepts and key principles of the different MIP-based catalystsFeatures state-of-the art presentation of preparation methods and applications of MIPsWritten by scientists from prestigious universities and industries across the world, and edited by veteran researchers in molecular imprinting and selective catalysis
Book
1 online resource.
  • Introduction.- Bonn Agreement Actions to Eliminate Illegal and Accidental Oil Pollution from Ships in the North Sea.- European Maritime Safety Agency CleanSeaNet Activities in the North Sea.- The Role of the International Maritime Organization in the Prevention of Illegal Oil Pollution from Ships.- North Sea Special Status Area.- Oil Pollution in the waters of the Danish North Sea.- Oil Pollution in the waters of Belgium.- Oil Pollution in the waters of the Netherlands.- Oil Pollution in the waters of The United Kingdom North Sea.- The German Operational Monitoring System in The North Sea: Sensors, Methods, and Example Data.- Monitoring oil pollution in the North Sea using beached bird surveys.- Monitoring oil pollution from oil installations in the North Sea.- Oil Spill Sampling and the Bonn-Oil Spill Identification Network - a common method for oil spill identification.- OSPAR Review of the State of the North Sea - oil spills and their impact on the marine environment of the North Sea.- Conclusions.
  • (source: Nielsen Book Data)
This volume offers a review of measures taken at different levels to prevent oil inputs to the North Sea from sources such as shipping and oil installations. A range of data from satellites, remote sensing, aerial surveillance, in-situ monitoring, oil spill sampling and beached bird surveys presents a comprehensive portrait of trends in oil pollution over many years. Topics include Bonn Agreement-based actions to eliminate illegal and accidental pollution from ships, OSPAR monitoring of oil installations, EMSA CleanSeaNet activities, and an internationally approved common standard for oil spills presented by the Bonn-OSINet. A chapter on the role of the IMO in preventing oil pollution from ships provides an international context, while others discuss efforts being made at the national level. A decadal review of the state of the North Sea prepared by OSPAR supports the view that there has been a significant reduction of oil inputs to the sea. This thorough review addresses national and international agencies and government bodies, as well as policymakers and practitioners in the fields of shipping, ports and terminals, oil extraction and marine management. Further, it provides researchers with essential reference material on tools and techniques for monitoring oil pollution and offers a valuable resource for undergraduate and post-graduate students in the field of marine oil pollution.
(source: Nielsen Book Data)
Book
1 online resource (1 p. ) : digital, PDF file.
Recently, it has been predicted that topological crystalline insulators (TCIs) may exist in SnTe and Pb<sub>1-x</sub>Sn<sub>x</sub>Te thin films [1]. To date, most studies on TCIs were carried out either in bulk crystals or thin films, and no research activity has been explored in heterostructures. We present here the results on electronic transport properties of the 2D electron gas (2DEG) realized at the interfaces of PbTe/ CdTe (111) heterostructures. Evidence of topological state in this interfacial 2DEG was observed.
Book
1 online resource
Rapid Detection of Food Adulterants and Contaminants: Theory and Practice contains solid information on common adulterants and contaminants in various foods, guidelines for different standards, permissible limits prescribed by food regulatory authorities, and related detection techniques. This is an essential reference for anyone interested in progressive research on detection methods for food safety, especially researchers engaged in developing fast, reliable, and often nondestructive methods for the evaluation of food safety. * Reviews the most common detection methods of food adulterants and contaminants* Includes supporting theory behind the latest techniques* Presents case studies to better understand practical applications and resources for further research* Addresses the safety standards of a variety of governments and serves as a reference for why government procedures are put in place.
(source: Nielsen Book Data)
Book
1 online resource (12 p. ) : digital, PDF file.
In this memorandum, the chemical and radionuclide contaminant results from the Fourth Quarter Calendar Year 2015 (CY15) sample of Tank 50H salt solution are presented in tabulated form. The Fourth Quarter CY15 Tank 50H samples were obtained on October 29, 2015 and received at Savannah River National Laboratory (SRNL) on October 30, 2015. The information from this characterization will be used by Defense Waste Processing Facility (DWPF) & Saltstone Facility Engineering for the transfer of aqueous waste from Tank 50H to the Salt Feed Tank in the Saltstone Production Facility, where the waste will be treated and disposed of in the Saltstone Disposal Facility. This memorandum compares results, where applicable, to Saltstone Waste Acceptance Criteria (WAC) limits and targets. Data pertaining to the regulatory limits for Resource Conservation and Recovery Act (RCRA) metals will be documented at a later time per the Task Technical and Quality Assurance Plan (TTQAP) for the Tank 50H saltstone task. The chemical and radionuclide contaminant results from the characterization of the Fourth Quarter Calendar Year 2015 (CY15) sampling of Tank 50H were requested by SRR personnel and details of the testing are presented in the SRNL Task Technical and Quality Assurance Plan.
Book
1 online resource (17 p. ) : digital, PDF file.
Strip Effluent Hold Tank (SEHT) and Decontaminated Salt Solution Hold Tank (DSSHT) samples from several of the “microbatches” of Integrated Salt Disposition Project (ISDP) Salt Batch (“Macrobatch”) 7B have been analyzed for 238Pu, 90Sr, 137Cs, cations (Inductively Coupled Plasma Emission Spectroscopy - ICPES), and anions (Ion Chromatography Anions - IC-A). The analytical results from the current microbatch samples are similar to those from previous macrobatch samples. The Actinide Removal Process (ARP) and the Modular Caustic-Side Solvent Extraction Unit (MCU) continue to show more than adequate Pu and Sr removal, and there is a distinct positive trend in Cs removal (increasing cesium decontamination), due to the use of the Next Generation Solvent (NGS). The bulk chemistry of the DSSHT and SEHT samples do not show any signs of unusual behavior.
Book
1 online resource : chiefly color illustrations.
  • Introduction.- Basics of Raman scattering (RS) spectroscopy.- Basics of surface-enhanced Raman scattering (SERS).- Bioanalytical SERS applications.- Biomolecular SERS applications.- SERS investigations of cells, viruses and microorganisms.- Medical applications of SERS.- Conclusions and outlook.
  • (source: Nielsen Book Data)
This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
(source: Nielsen Book Data)

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