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- Cham, Switzerland : Springer, 2020.
- Description
- Book — 1 online resource
- Summary
-
- Part I: Bowel Endometriosis
- 1. Pathogenesis of Bowel Endometriosis2. Epidemiology of Bowel Endometriosis3. Pathologic characteristics of Bowel Endometriosis4. Symptoms of Bowel EndometriosisPart II: Diagnosis
- 5. Non-enhanced transvaginal ultrasonography
- 6. Enhanced ultrasonographic techniques7. Magnetic resonance imaging8. Multidetector computerized tomography enema9. Computed tomography colonoscopyPart III: Treatment10. Laparoscopic Discoid Rectal Endometriosis Resection-the Squeeze Technique
- 11. Conservative Surgery of Deep Bowel endometriosis12. Laparoscopic segmental bowel re
- section 13. Robotic treatment of bowel endometriosis
- 14. Short-term complications of surgery15. Long-term follow-up of patients undergoing surgical treatment of bowel endometriosis16. Hormonal treatment of bowel endometriosis17. Fertility and infertility treatments in patients with bowel endometriosis.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
2. The guts of the matter : a global history of human waste and infectious intestinal disease [2020]
- Webb, James L. A., Jr., 1952- author.
- Cambridge, Unted Kingdom ; New York, NY : Cambridge University Press, 2020
- Description
- Book — xiv, 210 pages : illustrations (black and white) ; 24 cm
- Summary
-
- Introduction--
- 1. Pathogens and parasites-- 1.1 Intestinal viruses, protozoa, and bacteria-- 1.2 Intestinal worms-- 1.3 Determinants of disease transmission-- 1.4 Changing perspectives on childhood diarrheal diseases-- 1.5 The microbiome-- 1.6 Historical epidemiology and contemporary interventions--
- 2. Early change-- 2.1 Rethinking the first epidemiological transition-- 2.2 Patterns of vulnerability-- 2.3 Zones of infectious intestinal disease-- 2.4 Eurasian attitudes toward human waste-- 2.5 Early urban sanitation--
- 3. Diffusion and amplification-- 3.1 The early diffusion of infectious intestinal disease to the Americas-- 3.2 The uses of human and animal wastes-- 3.3 Preindustrial urban sanitation redux-- 3.4 Urban crisis and the emergence of public health movements-- 3.5 Global cholera--
- 4. Innovations-- 4.1 The limited practical import of discoveries in epidemiology and bacteriology-- 4.2 Early sewerage-- 4.3 Death by sewage-- 4.4 The 'dry earth' and 'tub-and-pail' systems-- 4.5 Sewage farming and trenching-- 4.6 Flies, household hygiene, and contaminated milk-- 4.7 The typhoid fever vaccine-- 4.8 Water filtration and disinfection--
- 5. Adoptions and adaptations-- 5.1 Water and sanitation in Latin America-- 5.2 European colonial military sanitation-- 5.3 Water and sanitation in East Asia-- 5.4 Water and sanitation in tropical Africa-- 5.5 Water and sanitation in India-- 5.6 Global sanitation at mid-twentieth century--
- 6. The struggle against hookworm disease-- 6.1 Early control programs-- 6.2 The Rockefeller Sanitary Commission for the Eradication of Hookworm Disease-- 6.3 The Rockefeller Foundation's international programs-- 6.4 International Health Board (1916-1927)-- 6.5 Anemia as a diagnostic conundrum-- 6.6 The unmet challenges of human feces disposal-- 6.7 Assessments of the hookworm campaigns--
- 7. An era of optimism-- 7.1 Sanitary practices: soap, refrigeration, and screens-- 7.2 Vaccines against poliomyelitis-- 7.3 The revolution of oral rehydration therapy-- 7.4 The World Health Organization and sanitation initiatives-- 7.5 The first and second United Nations development decades (1960s-1970s)-- 7.6 The international drinking water and sanitation decade (1980s)--
- 8. Global health and infectious intestinal disease-- 8.1 The infant formula controversy-- 8.2 The child survival revolution-- 8.3 A new campaign to eradicate poliomyelitis-- 8.4 Total community led sanitation-- 8.5 Open defecation and the struggle for modernity-- 8.6 Deworming the world-- 8.7 Rotavirus vaccine-- 8.8 The seventh cholera pandemic-- 8.9 Infectious intestinal disease today-- Conclusion-- Bibliography.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Online
Green Library
Green Library | Status |
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RC860 .W39 2020 | Unknown |
- New York, NY : Humana Press, 2020.
- Description
- Book — 1 online resource
- Summary
-
- Part I: Characterization, Imaging, and Functional Assays
- 1. Identification and Isolation of Human LGR5+ Cells Using an Antibody-Based Strategy
- Michael K. Dame, Sha Huang, Durga Attili, Jason R Spence, and Justin A. Colacino
- 2. Immune-Mediated Specific Depletion of Intestinal Stem Cells
- Stephen E. Sherman and Judith Agudo
- 3. Analysis of Aged Dysfunctional Intestinal Stem Cells
- Kodandaramireddy Nalapareddy and Hartmut Geiger
- 4. Strategies for Measuring Induction of Fatty Acid Oxidation in Intestinal Stem and Progenitor Cells
- Chia-Wei Cheng, Omer H. Yilmaz, and Maria M. Mihaylova
- 5. Visualization of Stem Cell Niche by the Fluorescence Lifetime Imaging Microscopy
- Irina A. Okkelman, Jens Puschhof, Dmitri B. Papkovsky, and Ruslan I. Dmitriev
- 6. Generation and Quantitative Imaging of Enteroid Monolayers
- Laura E. Sanman, Ina W. Chen, Jake M. Bieber, Curtis A. Thorne, Lani F. Wu, and Steven J. Altschuler
- 7. Autophagy Detection in Intestinal Stem Cells
- Jumpei Asano, Taku Sato, and Toshiaki Ohteki
- Part II: Single-Cell Transcriptional Profiling of the Small Intestinal Epithelium
- 8. Single-Cell Transcriptional Profiling of the Intestinal Epithelium
- Claudia Capdevila, Ruben I. Calderon, Erin C. Bush, Kismet Sheldon-Collins, Peter A. Sims, and Kelley S. Yan
- 9. Single-Cell Studies of Intestinal Stem Cell Heterogeneity during Homeostasis and Regeneration
- Maxim Norkin, Claudia Capdevila, Ruben I. Calderon, Tianhong Su, Maria Trifas, Paloma Ordonez-Moran, and Kelley S. Yan
- Part III: Organoids and Applications
- 10. Large-Scale Production of Recombinant Noggin and R-Spondin1 Proteins Required for the Maintenance of Stem Cells in Intestinal Organoid Cultures
- David L. Hacker and Paloma Ordonez-Moran
- 11. Primary Intestinal Epithelial Organoid Culture
- Tomohiro Mizutani and Hans Clevers
- 12. In Vivo Human PSC-Derived Intestinal Organoids to Study Stem Cell Maintenance
- Simon Vales, Holly M. Poling, Nambirajan Sundaram, Michael A. Helmrath, and Maxime M. Mahe
- 13. Generation of Knock-Out Gene-Edited Human Intestinal Organoids
- Chathruckan Rajendra, Tomas Wald, Kevin Barber, Jason R. Spence, Faranak Fattahi, and Ophir D. Klein
- 14. Direct Lineage Reprogramming of Mouse Fibroblasts to Acquire the Identity of Fetal Intestine-Derived Progenitor Cells
- Shizuka Miura and Atsushi Suzuki
- 15. Single Molecule RNA FISH in Whole-Mount Organoids
- Costanza Borrelli and Andreas E. Moor
- 16. Specific Gene Expression in Lgr5+ Stem Cells by Using Cre-Lox Recombination
- Pierre Dessen, Joerg Huelsken, and Paloma Ordonez-Moran
- 17. Generating and Utilizing Murine Cas9-Expressing Intestinal Organoids for Large Scale Knockout Genetic Screening
- Hossein Kashfi, Nicholas Jinks, and Abdolrahman Shams Nateri
- Part IV: In Vivo Models
- 18. Mouse Model for Sporadic Mutation of Target Alleles to Understand Tumor Initiation and Progression and Stem Cell Dynamics
- Theresa Nguyen, Elise Manalo, Taryn Kawashima, and Jared M. Fischer
- 19. Hemagglutinating Virus of Japan Envelop (HVJ-E)-Guided Gene Transfer to the Intestinal Epithelium
- Masamichi Imajo
- 20. An Intrasplenic Injection Model for the Study of Cancer Stem Cells Seeding Capacity
- Caroline Dafflon, Albert Santamaria-Martinez, and Paloma Ordonez-Moran
- 21. Organoid Derivation and Orthotopic Xenotransplantation for Studying Human Intestinal Stem Cell Dynamics
- Shinya Sugimoto, Masayuki Fujii, and Toshiro Sato
- 22. Advanced Colorectal Cancer Orthotopic Patient-Derived Xenograft Models for Cancer and Stem Cell Research
- Irene Chicote, Juan Antonio Camara, and Hector G. Palmer
- 23. Modeling Colorectal Cancer Progression through Orthotopic Implantation of Organoids
- Felipe de Sousa e Melo, Jonathan M. Harnoss, Noelyn Kljavin, Ryan Scott, Catherine Sohn, Kevin G. Leong, and Frederic J. de Sauvage.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
4. Suprapontine lesions and neurogenic pelvic dysfunctions : assessment, treatment and rehabilitation [2020]
- Cham : Springer, [2020]
- Description
- Book — 1 online resource.
- Summary
-
- Micturition Control.- Bowel Control.- Micturition Reflexes.- Somatic Innervation Of The Perineum.- Superficial (Esteroceptive) Reflexes.- Adult Neurogenic Lower Urinary Tract Dysfunctions.- Neurogenic Bowel Dysfunction.- Ischemic And Haemorrhagic Stroke.- Parkinson Disease.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Pan, Weihong. (BioPotentials Sleep Center, USA) Speaker
- London : Henry Stewart Talks, 2019
- Description
- Video — 1 online resource (1 streaming video file (19 min.) : color, sound)
- Summary
-
- Contents: Glial cells in the reaction and regulation of obesity
- The gut as a large immune organ, and interface with the BBB
- "Vascular, glial, and lymphatic immune gateways" of neuroimmune modulation
- Metabolic changes of the BBB in obesity besides cytokine transport across the BBB
- Implications in the pathophysiology of neurodegenerative diseases
- Cham, Switzerland : Springer, 2019.
- Description
- Book — online resource (xvi, 496 pages) : 65 illustrations, 33 in color
- Summary
-
- Intro
- Preface
- Contents
- Contributors
- Part I: Nausea and Vomiting
- Chapter 1: Approach to Nausea and Vomiting
- Case Study
- Objectives
- Epidemiology
- Pathophysiology
- Etiology
- Diagnostic Evaluation
- Treatment
- Clinical Case Study Follow-Up
- Self-Test
- References
- Essential Reading
- Chapter 2: Gastroparesis
- Case Study
- Objectives
- Epidemiology
- Symptoms
- Diagnostic Evaluation
- Treatment
- Symptom Management
- Prokinetics
- Prokinetics in Development
- Pyloric Interventions
- Gastric Electrical Stimulation
- Case Study: Follow-Up
- Self-Test
- References
- Essential Reading
- Chapter 3: Nausea and Vomiting of Pregnancy and Postoperative Nausea and Vomiting
- Case Study 1
- Case Study 2
- Objectives
- Nausea and Vomiting of Pregnancy
- Epidemiology
- Etiology/Pathophysiology
- Diagnosis
- Treatment
- First-Line Therapy
- Second-Line Treatment
- Third-Line Treatment
- Postoperative Nausea and Vomiting
- Epidemiology
- Pathophysiology
- Etiology
- Diagnosis
- Treatment
- 5-Hydroxytryptamine Receptor Antagonists
- Corticosteroids
- Anticholinergics
- Neurokinin-1 Receptor Antagonists
- Dopamine Receptor Antagonists
- Antihistamines
- Other PONV Treatment Options
- Case Study: Follow-Up
- Self-Test Questions
- References
- Essential Reading List
- Chapter 4: Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis Syndrome
- Case Study
- Objectives
- Epidemiology
- Etiology/Pathophysiology
- Symptoms
- Diagnostic Evaluation
- Treatment
- Case Study: Follow-Up
- Self-Test
- References
- Essential Reading
- Chapter 5: Chronic Intestinal Pseudo-Obstruction
- Case Study
- Objectives
- Epidemiology
- Classification
- Etiology and Pathophysiology
- Neuropathies
- Intestinal Myopathies
- Mesenchymopathies
- Symptoms
- Diagnosis
- Treatment
- Nutrition Assessment
- Oral Diet
- Enteral Nutrition Considerations
- Parenteral Nutrition Considerations
- Medications and Other Therapies
- Fecal Transplant
- GI Decompression
- Small Intestinal Transplantation
- Case Study Follow-Up
- Self-Test
- References
- Essential Reading
- Part II: Dyspepsia and Other Disorders of Neuromuscular Function
- Chapter 6: A Diagnostic Approach to Dyspepsia
- Case Study
- Objectives
- Epidemiology
- Etiology and Pathophysiology
- Symptoms
- Diagnostic Evaluation
- Treatment
- Case Study: Follow-Up
- Self-Test
- References
- Essential Reading
- Chapter 7: Helicobacter pylori and Related Diseases
- Case
- Objectives
- Epidemiology
- Etiology and Pathophysiology
- Symptoms
- Diagnostic Evaluation
- Treatment
- Case Study: Follow-Up
- Self-Test
- References
- Essential Reading
- Chapter 8: Functional Dyspepsia
- Case
- Objectives
- Epidemiology
- Etiology and Pathophysiology
- Symptoms
- Diagnostic Evaluation
- Treatment
- Helicobacter Pylori
- Acid Suppression
- Antidepressants
- Prokinetics
- Further Options
- Case Study: Follow-Up
- Self-Test
- References
- Essential Reading
- Chapter 9: Rumination Syndrome
- Case Study
- Objectives
- Epidemiology
- Etiology and Pathophysiology
- Symptoms
- Diagnostic Evaluation
- Treatment
- Case Study: Follow-Up
- Online
Medical Library (Lane)
Medical Library (Lane) | Status |
---|---|
Check Lane Library catalog for status | |
SPRINGER | Unknown |
- BOCA RATON : CRC PRESS, 2019
- Description
- Book — 1 online resource
- Summary
-
- 1. Physiology of the Intestinal Immune System
- Graham Mayrhofer
- 2. Induction and Control of Intestinal Immune Responses
- Christopher R. Stokes
- 3. Protective Immune Responses in the Intestinal Tract
- Timothy J. Newby
- 4. The Immunopathogenesis of Food-Sensitive Enteropathies
- Allan McI. Mowat.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Cambridge, MA : Academic Press, 2018.
- Description
- Book — 1 online resource.
- Summary
-
- 1. Normal Anatomy, Digestion, Absorption
- 2. Short Bowel Syndrome (SBS): Classification, Underlying Causes, and Global Footprint
- 3. Fluids and Electrolytes: Challenges with Short Bowel Syndrome
- 4. Gut Microbiome
- 5. Therapeutic Diet Modifications in Short Bowel Syndrome
- 6. Probiotics and Prebiotics
- 7. Enteral Nutrition and Access in SBS
- 8. Parenteral Support and Access (including alternative intravenous lipid emulsions, home parenteral support)
- 9. Metabolic Complications of HPN/SBS (MBD, dehydration, d-lactic acidosis)
- 10. Hepatobilliary Complications of HPN/SBS
- 11. Catheter / Infectious Complications (of Home Parenteral Nutrition)
- 12. Antidiarrheals, Antisecretory Agents, Pancreatic Enzymes
- 13. Antimicrobials for Bacterial Overgrowth
- 14. Intestinal Lengthening Procedures
- 15. Intestinal Transplantation (Indications, outcomes, challenges after transplant).
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Tokyo, Japan : Springer Nature, [2018]
- Description
- Book — 1 online resource.
- Summary
-
- Preface; Contents; Part I: The Role of Endoscopy in IBD;
- Chapter 1: The Role of Endoscopy in Inflammatory Bowel Disease; 1.1 Introduction; 1.2 Feasibility of Endoscopy in Active UC; 1.3 Mucosal Healing Evaluated by Endoscopy Contributes to a Better Outcome in UC; 1.4 Endoscopic Severity of UC Contributes to an Increased Risk of Colectomy; 1.5 Severe Mucosal Lesions of Colonic CD Evaluated by Endoscopy; 1.6 Mucosal Healing Evaluated by Endoscopy after Medical Treatment against CD; 1.7 Endoscopic Assessment Contributes in Predicting Relapses of CD after Surgery; 1.8 Conclusion; References
- Chapter 2: Current Progress of Endoscopy in Inflammatory Bowel Disease: Colonoscopy2.1 Introduction; 2.2 Bowel Preparation and Additional Cleansing during Colonoscopy; 2.3 Recent Advances in Endoscopic Equipment; 2.4 Diagnosis of IBD and Differential Diagnosis; 2.4.1 Ulcerative Colitis; 2.4.2 Crohn's Disease; 2.5 Colonoscopic Follow Up; 2.5.1 Monitoring of Ulcerative Colitis; 2.5.2 Monitoring of Crohn's Disease; 2.6 Cancer Surveillance; 2.7 Summary; References;
- Chapter 3: Current Progress of Endoscopy in Inflammatory Bowel Disease: Balloon-Assisted Enteroscopy
- 3.1 Small Bowel Endoscopy in the Twentieth Century3.2 New Generation of Small-Bowel Endoscopy; 3.2.1 Double-Balloon Endoscopy (DBE); 3.2.2 Single-Balloon Endoscopy (SBE); 3.2.3 Spiral Endoscopy (SE); 3.2.4 Usefulness of Insufflation of Carbon Dioxide Gas; 3.2.5 Usefulness of Selective Contrast Study; 3.3 Advantages of BAE in Diagnosis and Treatment of IBD; 3.3.1 Diagnostic Phase; 3.3.2 Follow-Up Phase; 3.3.3 Endoscopic Balloon Dilation; 3.3.4 Preoperative Close Examination Phase; 3.3.5 Postoperative Follow-Up (Kono-S Anastomosis is Recommended instead of Functional End-to-End Anastomosis)
- 3.3.6 Limitations of BAEReferences;
- Chapter 4: Current Progress of Endoscopy in Inflammatory Bowel Disease: Capsule Endoscopy; 4.1 Introduction; 4.2 Small-Bowel VCE for IBD; 4.3 Colon CE for IBD; 4.4 Recent Advances in CE; 4.5 Summary; References;
- Chapter 5: Current Progress of Endoscopy in Inflammatory Bowel Disease: CT Enterography and CT Colonography in Inflammatory Bowel Disease; 5.1 Introduction; 5.2 CT Enterography; 5.3 Technique; 5.4 Findings of IBD; 5.5 CT Colonography; 5.6 Technique; 5.7 Findings of IBD; 5.8 Limitations; 5.9 CTE and CTC with Low-Dose CT Technique; 5.10 Summary
10. Clostridia in gastrointestinal disease [2018]
- First edition - Boca Raton, FL : CRC Press, 2018
- Description
- Book — 1 online resource
- Summary
-
- chapter 1 Clostridia in the Human Gastrointestinal Flora / W. Lance George Sydney M. Finegold
- chapter 2 Infant Botulism / Stephen S. Arnon
- chapter 3 Evidence for Clostridial Involvement in Pneumatosis Cystoides Intestinalis / C. E. Yale E. Balish
- chapter 4 The Role of Clostridia in the Pathogenesis of Neonatal Necrotizing Enterocolitis / R. M. Kliegman
- chapter 5 Pig-Bel / P. D. Walker
- chapter 6 Clostridium Perfringens Type a Food Poisoning / M. F. Stringer
- chapter 7 Pseudomembranous and Antibiotic-Associated Colitis / S. P. Borriello H. E. Larson
- chapter 8 Clostridia and Human Colorectal Cancer / M.J. Hill
- chapter 9 Histopathology of Clostridial Gut Diseases in Man / Ashley B. Price
- chapter 10 Clostridial Diseases of the Gastrointestinal Tract in Animals / S. P. Borriello Carman Robert J.
- chapter 11 Newly Described Clostridial Diseases of the Gastrointestinal Tract: Clostridium Perfringens Enterotoxin-Associated Diarrhea and Neutropenic Enterocolitis Due to Clostridium Septicum / S.P. Borriello
(source: Nielsen Book Data)
- Gewirtz, Andrew, (Georgia State University, USA) Speaker
- London : Henry Stewart Talks, 2018.
- Description
- Video — 1 online resource (1 streaming video file (46 min.) : color, sound).
- Summary
-
- Contents: Managing intestinal bacteria
- Toll-like receptors
- Flagellin
- Enhancing inflammation through blockade of a pro-inflammatory signaling pathway
- T5KO mice
- Embryo transfer
- Loss of TLR5 and alteration of the composition of the gut microbiota
- Possible role of gut microbiota in metabolic syndrome and relevance in humans
- The human gut microbiota in the last 50-100 years
- Dietary disturbance of the gut microbiota & metabolic syndrome.
- Darm mit Charme. English
- Enders, Giulia author.
- Revised edition. - Vancouver : Greystone Books, [2018]
- Description
- Book — 293 pages : illustrations ; 22 cm
- Summary
-
- Gut feeling. How does pooping work? And why that's an important question ; The gateway to the gut ; The structure of the gut ; What we really eat ; Allergies and intolerances
- The nervous system of the gut. How our organs transport food ; Reflux ; Vomiting ; Constipation ; The brain and the gut
- The world of microbes. I am an ecosystem ; The immune system and out bacteria ; The development of the gut flora ; The adult gut population ; The role of the gut flora ; The bad guys: harmful bacteria and parasites ; Of cleanliness and good bacteria
- Update on the brain-but connection. New discoveries ; Clever cravings for fermented foods.
- Online
Green Library
Green Library | Status |
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QP145 .E5413 2018 | Unknown |
13. Health through inner body cleansing : the famous F.X. Mayr intestinal therapy from Europe [2017]
- Darmreinigung nach Dr. med F.X. Mayr. English
- Rauch, Erich, author.
- Seventh edition. - Stuttgart ; New York : Thieme, [2017]
- Description
- Book — 1 online resource
- Summary
-
The Mayr program, developed by the Austrian physician Dr. Franz Xaver Mayr (1875-1965), is an intensive regime lasting several weeks. It includes therapeutic fasts to rest the digestive tract, and it features a special diet to train proper mastication. This diet program is complemented with abdominal massage, hydrotherapy, and exercise. By following the F. X. Mayr method, patients can rejuvenate their dietary system and eliminate a whole host of ailments-from aches and pains, to depression, fatigue, and serious cardiac disorders. At the same time, they can reduce weight, improve their skin, and boost their sense of well-being. The author Dr. Erich Rauch was a personal student of Dr. F. X. Mayr. Over decades he supervised more than 40,000 Mayr therapies. For the practitioner as well as the patient in the clinic, his in-depth guide is the leading authority on the F. X. Mayr method. As a companion book it provides effective support for each stage of this successful therapy.
(source: Nielsen Book Data)
- Nestlé Nutrition Workshop (88th : 2016 : Playa del Carmen, Mexico)
- Basel, Switzerland : Karger : Nestle Nutrition Institute, 2017.
- Description
- Book — online resource (xiii, 175 pages) : illustrations
- Online
Medical Library (Lane)
Medical Library (Lane) | Status |
---|---|
Check Lane Library catalog for status | |
KARGER | Unknown |
- Price, Donald L., author.
- First edition - Boca Raton, FL : CRC Press, 2017
- Description
- Book — 1 online resource : text file, PDF
- Summary
-
- Part
- Part 1
- chapter 1 The Specimen
- part
- Part 2
- chapter 2 The Microscope and Examination of the Specimen
- part
- Part 3
- chapter 3 Concentration Methods
- chapter 4 Stains and Staining Methods
- chapter 5 Application of Methods
- chapter 6 Special Methods
- part
- Part 4
- chapter 7 Introduction to the Parasites
- chapter 8 The Helminths
- chapter 9 The Protozoa
- chapter 10 Nonhuman Parasites and Structures that Mimic Parasites
- Cham, Switzerland : Springer, 2016.
- Description
- Book — 1 online resource Digital: text file; PDF.
- Summary
-
- Part 1. Introduction.-
- 1. Background to bowel function and rationale for writing the book.-
- 2. Normal anatomy and physiology of bowel function with a view to including detail on the pelvic floor.-
- 3. Epidemiology Constipation and FI.-
- 4. Investigations: Anorectal Physiology.-
- Part 2. Causes and Assessment of Bowel Dysfunction.-
- 5. Causes of constipation/evacuatory dysfunction.-
- 6. The Assessment of Constipation and Evacuatory Disorders.-
- 7. Causes of faecal incontinence.-
- 8. The Assessment of Faecal Incontinence.-
- Part 3. Treatments for Bowel Dysfunction.-
- 9. Conservative management.-
- 10. Food choice as a Management Strategy in Bowel Dysfunction.-
- 11. Pharmacological therapy.-
- 12. Rectal Irrigation.-
- 13. Neuromodulation.-
- 14. Surgery .-
- 15. Psychological medicine for bowel dysfunction.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
17. Current concepts of intestinal failure [2016]
- Switzerland : Springer, 2016.
- Description
- Book — online resource (vii, 163 pages) : illustrations
- Summary
-
- Intestinal failure in children
- Short Bowel Syndrome-Intestinal Adaptation
- Bacterial Overgrowth and Intestinal Microbiome
- Intestinal failure-associated liver disease
- Recent Advances in Nutritional Care of Patients with Intestinal Failure
- Pharmacological improvement of bowel function and adaptation
- Modern Intestinal rehabilitation and outcomes
- Serial transverse enteroplasty
- Longitudinal intestinal lengthening
- Controlled tissue expansion
- Pediatric small bowel transplantation
- an update
- Intestinal Regeneration
- distraction enterogenesis.
- Online
Medical Library (Lane)
Medical Library (Lane) | Status |
---|---|
Check Lane Library catalog for status | |
SPRINGER | Unknown |
18. Current concepts of intestinal failure [2016]
- Switzerland : Springer, 2016.
- Description
- Book — 1 online resource
- Summary
-
- Intestinal failure in children.- Short Bowel Syndrome-Intestinal Adaptation.- Bacterial Overgrowth and Intestinal Microbiome.- Intestinal failure-associated liver disease.- Recent Advances in Nutritional Care of Patients with Intestinal Failure.- Pharmacological improvement of bowel function and adaptation.- Modern Intestinal rehabilitation and outcomes.- Serial transverse enteroplasty.- Longitudinal intestinal lengthening.- Controlled tissue expansion.- Pediatric small bowel transplantation - an update.- Intestinal Regeneration.- distraction enterogenesis.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
19. Inflammatory intestinal diseases [2016 - ]
- Basel, Switzerland : S. Karger AG, [2016]-
- Description
- Journal/Periodical — 1 online resource
20. Metabolic communication in development and control of obesity -- part 2 of 2 [electronic resource] [2016]
- Holmes, Elaine (Imperial College London, UK) Speaker
- London : Henry Stewart Talks, 2016.
- Description
- Video — 1 online resource (1 streaming video file (25 min.) : color, sound).
- Summary
-
- Contents: Surgical intervention in obesity
- Bariatric surgery and microbe-host interaction
- Metabolic surgery and cancer
- Predicted pathways – miRNAs
- miR122 analysis in RYGB vs. sham
- Inflammation and cancer
- Targeted profiling of inflammation
- The early life environment shapes the microbiome
- Preterm birth and increased disease risk
- Pharmacometabonomics.
- Boca Raton : CRC Press, Taylor & Francis Group, [2016]
- Description
- Book — 1 online resource : text file, PDF
- Summary
-
- Short Bowel Syndrome: Definition, Classification, Etiology, Epidemiology, Survival, and Costs Palle B. Jeppesen Psychological, Social, and Quality of Life Considerations in Short Bowel Syndrome James M. Badger and Marion F. Winkler Short Bowel Syndrome: Anatomical and Physiological Considerations Jeremy Nightingale Intestinal Adaptation: The Contemporary Treatment Goal for Short Bowel Syndrome Jane Naberhuis and Kelly A. Tappenden Diarrhea in Short Bowel Syndrome Badr Al-Bawardy and Vandana Nehra Electrolyte and Acid-Base Disturbances Lingtak-Neander Chan and Berkeley N. Limketkai Cholelithiasis and Nephrolithiasis Andrew Ukleja and John Rivas Metabolic Bone Disease in Adults with Short Bowel Syndrome Lynn R. Mack and Fedja A. Rochling Clinical and Nutritional Assessment in the Patient with Short Bowel Syndrome Denise Konrad and Betsy Gallant Diet Considerations in Short Bowel Syndrome Rebecca A. Weseman and Laura E. Beerman Maintaining Hydration in the Short Bowel Patient Bethany E. Blalock and Carol Rees Parrish Vitamins: Supplementation and Monitoring Elizabeth A. Wall Management of Trace Elements in Short Bowel Syndrome Joe Krenitsky Enteral Feeding in Short Bowel Syndrome Lore Billiauws, Emilie Latour Beaudet, and Francisca Joly Parenteral Nutrition for Short Bowel Syndrome: Practical Aspects Laura Matarese and Glenn Harvin Drug Delivery and Bioavailability in Short Bowel Syndrome Lingtak-Neander Chan The Role of Antimotility and Antisecretory Agents in the Management of Short Bowel Syndrome Mandy L. Corrigan and Donald F. Kirby Luminally Active Therapies: Pancreatic Enzymes, Bile Acids, Bile Acid Binders, Antimicrobials, Probiotics, and Prebiotics in Short Bowel Syndrome Eamonn M.M. Quigley Glucagon-Like Peptide-2 in Short Bowel Syndrome James S. Scolapio and Matt Clark Utility of Growth Hormone and Other Potential Agents to Restore Enteral Autonomy in Short Bowel Syndrome John K. DiBaise Surgical Considerations in the Short Bowel Syndrome Jon S. Thompson Ostomy, Fistula, and Skin Management Christine T. Berke and Cathi Brown Autologous Gastrointestinal Reconstruction David F. Mercer Intestinal Transplantation Sherilyn Gordon Burroughs and Douglas G. Farmer Home Parenteral Nutrition Initiation, Monitoring, and Weaning Jithinraj Edakkanambeth Varayil, John K. DiBaise, and Ryan T. Hurt Intestinal Failure-Associated Liver Disease Deirdre A. Kelly and Sue V. Beath Central Venous Catheter Complications: Management and Prevention Richard Gilroy, Jordan Voss, and Chaitanya Pant Meeting the Unmet Needs of Home Parenteral and Enteral Nutrition Consumers: Education, Networking, and Support Darlene G. Kelly, Joan Bishop, and Harlan Johnson Patient and Caregiver Perspectives: Learn and Live! Lynn Ruse and Jim Ruse.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- New York : Nova Biomedical, 2016.
- Description
- Book — 1 online resource
- Summary
-
- Preface-- Short Bowel Syndrome (SBS): Symptoms, Surgical Outcomes & Complications-- Short Bowel Syndrome: Clinical Features & Management-- Surgical Management of Short Bowel Syndrome: Current Intestinal Lengthening Techniques-- Related Nova Publications-- Bibliography-- Index.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Sakurai, Hiroyuki. (Kyorin University School of Medicine, Japan) Speaker
- London : Henry Stewart Talks, 2016.
- Description
- Video — 1 online resource (1 streaming video file (52 min.) : color, sound).
- Summary
-
- Contents: Urate physiology and pathophysiology
- Physiology of trans-epithelial movement of the solute
- Urate handling in the kidney
- Urate handling in the intestine
- Drugs and urate.
- Collen, Alanna, author.
- First U.S. edition. - New York, NY : HarperCollins Publishers, 2015.
- Description
- Book — 327 pages, 16 unnumbered pages of plates : illustrations (some color), maps (color) ; 24 cm
- Summary
-
"You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases--obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer--have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life--and your body--will never seem the same again"-- Provided by publisher.
"An argument for the importance of gut bacteria in the human body and how this affects our health and well-being"-- Provided by publisher.
- Online
Science Library (Li and Ma)
Science Library (Li and Ma) | Status |
---|---|
Stacks | Request (opens in new tab) |
QR171 .I6 C65 2015 | Unknown |
25. Abdominal solid organ transplantation : immunology, indications, techniques, and early complications [2015]
- Cham : Springer, [2015]
- Description
- Book — online resource (ix, 453 pages) : illustrations
- Summary
-
- 1. Immunosuppression in solid organ transplantation
- 2. Infection Complications after Abdominal Organ Transplantation
- 3. National Transplant Network. Donor selection and evaluation criteria
- 4. The safety of donor
- 5. Medical disease after abdominal solid organ transplantation and the risk of solid and hematologic malignant tumor after transplantation)
- 6 Indication and timing
- 7. The donor procurement
- 8. Orthotopic liver transplantation
- 9. Anesthetic and perioperative management for liver transplantation
- 10 Living donor liver transplantation
- 11. Hepatic Acute and chronic rejection
- 12. Postoperative technical complications
- 13. Percutaneous management of biliary and vascular complications
- 14. Re-transplantation (Causes, Outcome)
- 15. Indication and timing
- 16. The donor procurement: Standard technique for procurement in cadaveric donors
- 17. Live donor evaluation
- 18. Living donor nephrectomy
- 19. Renal Transplantation: Surgical technique
- 20. The intraoperative and perioperative management of Kidney transplantation
- 21. Kidney acute and chronic rejection
- 22. Kidney Transplantation: Post-Operative Technical Complications
- 23. Indications and timing
- 24. The donor procurement
- 25 Transplantation
- 26 Abdominal wall transplantation and technique
- 27. Anesthetic and perioperative management for Intestinal transplantation
- 28. Segmental Living-related Small Bowel Transplantation
- 29. Intestinal Acute and Chronic rejection
- 30. Combined Kidney-Liver Transplantation
- 31. Kidney-pancreas Transplantation.
- Online
Medical Library (Lane)
Medical Library (Lane) | Status |
---|---|
Check Lane Library catalog for status | |
SPRINGER | Unknown |
26. Abdominal solid organ transplantation : immunology, indications, techniques, and early complications [2015]
- Cham : Springer, [2015]
- Description
- Book — 1 online resource Digital: text file; PDF.
- Summary
-
- Part I Donor evaluation, immunosuppression and early complications in S.O.T.: 1 Immunosuppression in solid organ transplantation.- 2 Infection Complications after Abdominal Organ Transplantation.- 3 National Transplant Network. Donor selection and evaluation criteria.- 4 The safety of donor.- 5 Medical disease after abdominal solid organ transplantation and the risk of solid and hematologic malignant tumor after transplantation).- Part II Liver Transplantation: 6 Indication and timing.- 7 The donor procurement.- 8 Orthotopic liver transplantation.- 9 Anesthetic and perioperative management for liver transplantation.- 10 Living donor liver transplantation.- 11 Hepatic Acute and chronic rejection.- 12 Postoperative technical complications.- 13 Percutaneous management of biliary and vascular complications.- 14 Re-transplantation (Causes, Outcome).- Part III Renal transplantation: 15 Indication and timing.- 16 The donor procurement: Standard technique for procurement in cadaveric donors .- 17 Live donor evaluation.- 18 Living donor nephrectomy.- 19 Renal Transplantation: Surgical technique.- 20 The intraoperative and perioperative management of Kidney transplantation.- 21 Kidney acute and chronic rejection.- 22 Kidney Transplantation: Post-Operative Technical Complications.- Part V Intestinal/multivisceral transplantation: 23 Indications and timing.- 24 The donor procurement .- 25 Transplantation.- 26 Abdominal wall transplantation and technique.- 27 Anesthetic and perioperative management for Intestinal transplantation .- 28 Segmental Living-related Small Bowel Transplantation.- 29 Intestinal Acute and Chronic rejection.- Part VI Combined Abdominal Transplantation: 30 Combined Kidney-Liver Transplantation.- 31 Kidney-pancreas Transplantation.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Pfeiffer, Ronald. (University of Tennessee, USA) Speaker
- London : Henry Stewart Talks, 2015.
- Description
- Video — 1 online resource (1 streaming video file (67 min.) : color, sound).
- Summary
-
- Contents: Cardiovascular dysfunction (Denervation, Orthostatic hypotension)
- Gastrointestinal dysfunction (Excess saliva, Dysphagia, Gastroparesis, Small intestinal dysfunction, Bacterial overgrowth, Bowel dysfunction, Constipation, Defecatory dysfunction, Anorectal testing)
- Urinary dysfunction (Irritation, Obstruction)
- Sexual dysfunction
- Thermoregulatory dysfunction (Hyperthermia/Hypothermia, Dyshidrosis, Hyperhidrosis).
- Darm mit Charme. French
- Enders, Giulia author.
- Arles : Actes sud, [2015]
- Description
- Book — 350 pages, 1 unnumbered page : illustrations ; 22 cm
- Summary
-
"Surpoids, dépression, diabète, maladies de peau... et si tout se jouait dans l'intestin ? Au fil des pages de son brillant ouvrage, Giulia Enders, jeune doctorante en médecine, plaide avec humour pour cet organe qu'on a tendance à négliger, voire à maltraiter. Après une visite guidée au sein de notre système digestif, elle présente, toujours de façon claire et captivante, les résultats des toutes dernières recherches sur le rôle du "deuxième cerveau" pour notre bien-être. C'est avec des arguments scientifiques qu'elle nous invite à changer de comportement alimentaire, à éviter certains médicaments ainsi qu'à appliquer quelques règles très concrètes en faveur d'une digestion réussie. Irrésistiblement illustré par Jill Enders, la soeur de l'auteur, voici un livre qui nous réconcilie avec notre ventre. Succès surprise, Le Charme discret de l'intestin s'est vendu à plus de un million d'exemplaires en Allemagne et sera publié dans une trentaine de pays."--Page 4 of cover.
- Online
Green Library
Green Library | Status |
---|---|
Find it Stacks | Request (opens in new tab) |
QP156 .E6314 2015 | Unknown |
29. Health and the gut : the emerging role of intestinal microbiota in disease and therapeutics [2015]
- Toronto : Apple Academic Press ; Boca Raton, FL : CRC Press, [2015]
- Description
- Book — 1 online resource
- Summary
-
- Introduction
- Part I: Introduction: The Rainforest in the Gut
- Nutrition, Microbiomes, and Intestinal Inflammation-- Suzanne Devkota and Eugene B. Chang
- Part II: Microbiome's Role in Obesity
- Gut Microbiota: In Sickness and in Health-- M. Jose Huertas, and Carmen Michan
- Microbial Reprogramming Inhibits Western Diet-Associated Obesity-- Theofilos Poutahidis, Markus Kleinewietfeld, Christopher Smillie, Tatiana Levkovich, Alison Perrotta, Siddheshvar Bhela, Bernard J. Varian, Yassin M. Ibrahim, Jessica R. Lakritz, Sean M. Kearney, Antonis Chatzigiagkos, David A. Hafler, Eric J. Alm, Susan E. Erdman
- Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice-- Yan Y. Lam, Connie W. Y. Ha, Craig R. Campbell, Andrew J. Mitchell, Anuwat Dinudom, Jan Oscarsson, David I. Cook, Nicholas H. Hunt, Ian D. Caterson, Andrew J. Holmes, and Len H. Storlien
- Bacteroides uniformis CECT 7771 Ameliorates Metabolic and Immunological Dysfunction in Mice with High-Fat-Diet Induced Obesity-- Paola Gauffin Cano, Arlette Santacruz, Angela Moya, and Yolanda Sanz
- Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in Diet-Induced Obese Mice is Associated with Gut Microbial Changes and Reduction in Obesity-- Do-Young Park, Young-Tae Ahn, Se-Hoon Park, Chul-Sung Huh, Sae-Rom Yoo, Rina Yu, Mi-Kyung Sung, Robin A. McGregor, and Myung-Sook Choi
- Part III: Inflammation and Innate Immunity
- Antimicrobial Peptides and Gut Microbiota in Homeostasis and Pathology-- Maureen J. Ostaff, Eduard Friedrich Stange, and Jan Wehkamp
- Matrix Metalloproteinase 13 Modulates Intestinal Epithelial Barrier Integrity in Inflammatory Diseases by Activating TNF-- Roosmarijn E. Vandenbroucke, Eline Dejonckheere, Filip Van Hauwermeiren, SofieLodens, Riet De Rycke, Elien Van Wonterghem, An Staes, Kris Gevaert, Carlos Lopez-Otin, and Claude Libert
- Part IV: Nutrition's Effect on the Microbiome
- Impact of a Synbiotic Food on the Gut Microbial Ecology and Metabolic Profiles-- Beatrice Vitali, Maurice Ndagijimana, Federica Cruciani, Paola Carnevali, Marco Candela, Maria Elisabetta Guerzoni, and Patrizia Brigidi
- Diet-Microbiota Interactions and their Implications for Healthy Living-- Ian B. Jeffery and Paul W. O'Toole
- Part V: Using the Microbiome to Identify and Cure Disease
- Prebiotics, Faecal Transplants and Microbial Network Units to Stimulate Biodiversity of the Human Gut Microbiome-- Pieter Van den Abbeele, Willy Verstraete, Sahar El Aidy, Annelies Geirnaert, and Tom Van de Wiele
- Microbiota and Healthy Aging: Observational and Nutritional Intervention Studies-- Harald Brussow
- Gut Pharmacomicrobiomics: The Tip of an Iceberg of Complex Interactions between Drugs and Gut-Associated Microbes-- Rama Saad, Mariam R. Rizkallah, and Ramy K. Aziz
- Fame and Future of Fecal Transplantations: Developing Next-Generation Therapies with Synthetic Microbiomes-- Willem M. de Vos
- Index.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Cham : Springer, 2015.
- Description
- Book — 1 online resource (xi, 445 pages) : color illustrations Digital: text file; PDF.
- Summary
-
This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tumorigenesis lead to further understanding of mechanisms involved in colon cancer. Additionally, advancements in techniques and methods open the doors for new approaches to better define the molecular and organismal mechanisms of intestinal tumorigenesis. Chapters are authored by widely published authorities in the field. Each year, there are close to 150,000 new cases of colorectal cancer, which results in approximately 50,000 deaths per year in the United States; these figures render colorectal cancer a significant health concern. Studies attempting to understand the mechanisms of development and progression of colorectal cancer have been ongoing for decades and each year brings new discoveries yielding a better comprehension of the underlying processes at work.
- New York : Nova Biomedical, [2015]
- Description
- Book — 1 online resource (xii, 149 pages) : illustrations
32. Novel natural products : therapeutic effects in pain, arthritis and gastro-intestinal diseases [2015]
- Basel, Switzerland : Springer, 2015.
- Description
- Book — 1 online resource : illustration. Digital: text file; PDF.
- Summary
-
- Aloe vera: a Natural Healing Agent for Gastro-intestinal and Chronic Inflammatory Conditions
- Chondroitin Sulphate and Glucosamine Sulphate as Potential Disease-Modifying Agents for Osteoarthritis
- Probiotics as Natural Healing Agents for Gastro-intestinal Diseases and Arthritis.- Therapeutic Effects of Ribonucleinate (Ribonucleotides) in Immuno-inflammatory and Arthritic Diseases
- The Medicinal Properties and Phytochemistry of Plants of the Genus Terminalia (Combretaceae)
- Celery Seed and Related Extracts with Anti-athritic, Anti-Ulcer and anti-Microbial Activities
- Lyprinol, Lipids and other Components of Green Lipped Mussel as Anti-Arthritic and Anti-Ulcer Agents
- Zinc Compounds as Topical and Oral Anti-Arthritic and Anti-ulcer Compounds.
33. Novel natural products : therapeutic effects in pain, arthritis and gastro-intestinal diseases [2015]
- Basel, Switzerland : Springer, 2015.
- Description
- Book — online resource (vii, 286 pages) : illustration
- Summary
-
- Aloe vera: a Natural Healing Agent for Gastro-intestinal and Chronic Inflammatory Conditions
- Chondroitin Sulphate and Glucosamine Sulphate as Potential Disease-Modifying Agents for Osteoarthritis
- Probiotics as Natural Healing Agents for Gastro-intestinal Diseases and Arthritis.- Therapeutic Effects of Ribonucleinate (Ribonucleotides) in Immuno-inflammatory and Arthritic Diseases
- The Medicinal Properties and Phytochemistry of Plants of the Genus Terminalia (Combretaceae)
- Celery Seed and Related Extracts with Anti-athritic, Anti-Ulcer and anti-Microbial Activities
- Lyprinol, Lipids and other Components of Green Lipped Mussel as Anti-Arthritic and Anti-Ulcer Agents
- Zinc Compounds as Topical and Oral Anti-Arthritic and Anti-ulcer Compounds.
- Online
Medical Library (Lane)
Medical Library (Lane) | Status |
---|---|
Check Lane Library catalog for status | |
SPRINGER | Unknown |
- Sixth edition. - Boca Raton : CRC Press, Taylor & Francis Group, [2015]
- Description
- Book — 1 online resource : text file, PDF
- Summary
-
- General Principles. Preparation for colorectal surgery .Safety and positioning in the operating room. Access to abdominal cavity - open. Access to abdominal cavity - laparoscopic. Access to abdominal cavity - hand-assisted laparoscopic surgery. Single incision laparoscopic-assisted colectomy. Access to the abdominal cavity: natural orifice transluminal endoscopic surgery. Anastomotic technique - suture. Anastomotic technique - stapled. Specimen handling. Proctology. Office/outpatient set up. Proctosigmoidoscopy. Flexible endoscopy. Treatment of uncomplicated haemorrhoids. Excision of perianal thrombosis. Open hemorrhoidectomy. Closed hemorrhoidectomy. Stapled hemorrhoidopexy. Perianal sepsis. Anal fistula. Rectovaginal fistula repair. Anal fissure. Anoplasty. Perianal condyloma and anal intraepithelial neoplasia. Perianal skin and anal cancer Pilonidal disease. Stomas. Ileostomy. Colostomy. Stoma closure. Antegrade continence enema procedure in children. Antegrade continent enema procedure in adults. Small intestine. Small bowel resection. Meckel's diverticulum. Malrotation. Intestinal stricturoplasty. Adhesiolysis. Colon. Appendicectomy - open. Appendicectomy - laparoscopic. Right colectomy - open. Right hemicolectomy - laparoscopic. Right hemicolectomy - hand-assisted laparoscopic surgery. Left colectomy - open. Left hemicolectomy - laparoscopic. Left hemicolectomy - hand-assisted laparoscopic surgery. Colectomy - complete mesocolic excision. Total colectomy - laparoscopic. Total colectomy - HALS. Hartmann's procedure. Emergency colectomy. Colonic stenting. Rectum. Anterior resection of the rectum. Anterior resection - laparoscopic . Anterior resection - hand-assisted laparoscopic surgery. Anterior resection - robotic. Coloanal anastomosis with intersphincteric resection and colon J-pouch construction. Proctocolectomy for inflammatory bowel disease - open. Proctocolectomy for irritable bowel disease - laparoscopic. Continent ileostomy (Kock reservoir ileostomy). Restorative proctocolectomy with ileal reservoir .Abdominoperineal excision of the rectum and anus. Operative technique for pelvic exenteration. Pelvic exenteration: radical perineal approaches and sacrectomies. Lateral pelvic lymph node dis
- section in low rectal cancer. Transanal resection for rectal lesions. Transanal endoscopic microsurgery. Presacral resections - Kraske. Surgery for Hirschsprung's disease. The APPEAR procedure. Vertical reduction rectoplasty for idiopathic megarectum. Perineal reconstruction. VRAM flap. Martius flap. Local advancement flaps. Rectal prolapse. Delorme operation. Perineal rectosigmoidectomy. Abdominal rectopexy - open. Abdominal rectopexy - laparoscopic. Laparoscopic ventral rectopexy. STARR. The EXPRESS procedure. Surgery for incontinence. Surgical repair of the anal sphincters following injury. Sacral nerve stimulation. Construction of an electrically stimulated gracilis neoanal sphincter. Artificial bowel sphincter.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Farnham, Surrey ; Burlington, VT : Ashgate, [2015]
- Description
- Book — xii, 278 pages : illustrations, maps ; 24 cm
- Summary
-
- Contents: Why we need to know about sanitation in the past, Piers D. Mitchell-- Assessing the impact of sanitation upon health in early human populations from hunter-gatherers to ancient civilisations, using theoretical modelling, Piers D. Mitchell-- Waste management in early urban southern Mesopotamia, Augusta McMahon-- Latrines and wastewater sanitation technologies in ancient Greece, Georgios P. Antoniou and Andreas N. Angelakis-- A tale of two cities: the efficacy of ancient and medieval sanitation methods, Craig Taylor-- Sewers, cesspits and middens: a survey of the evidence for 2000 years of waste disposal in York, UK, Allan R. Hall and Harry K. Kenward-- Human intestinal parasites and dysentery in Africa and the Middle East prior to 1500, Evilena Anastasiou and Piers D. Mitchell-- Parasitism, cesspits and sanitation in East Asian countries prior to modernisation, Min Seo and Dong Hoon Shin-- New World paleoparasitology, Adauto Araujo, Luiz Fernando Ferreira, Martin Fugassa, Daniela Leles, Luciana Sianto, Sheila Maria Mendonca de Souza, Juliana Dutra, Alena Iniguez, Karl Reinhard-- Parasites in European populations from prehistory to the Industrial Revolution, Evilena Anastasiou-- A first attempt to retrace the history of dysentery caused by Entamoeba histolytica, Matthieu Le Bailly and Francoise Bouchet-- A better understanding of sanitation and health in the past, Piers D. Mitchell-- Bibliography-- Index.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Online
SAL3 (off-campus storage)
SAL3 (off-campus storage) | Status |
---|---|
Stacks | Request (opens in new tab) |
RA567 .S27 2015 | Available |
36. Semicolon : the adventures of ostomy girl [2014]
- [Boston, Massachusetts] : [Distributed by] Fanlight Collection, [2015]
- Description
- Video — 1 streaming video file (83 min.) : digital, sound, color
- Summary
-
25-year-old Dana lives with a severe case of Crohn's Disease that she battles every single day. It is unrelenting and she has been fighting it nearly all her life. Spending as much time in the hospital as out, Dana depends on intravenous nutrition, constant vigilance, and a wicked sense of humor to keep her alive. Now she faces the daunting task of deciding how she wants to live the rest of her life--coping with the limitations and rigors of her current routine or taking a leap of faith on a complicated transplant that could give her a chance at the normal life she has never known.
37. Identification of host defenses in the Drosophila gut using genome-scale RNAi [electronic resource] [2014]
- Ferrandon, Dominique. (French National Centre for Scientific Research, France) Speaker
- London : Henry Stewart Talks, 2014.
- Description
- Video — 1 online resource (1 streaming video file (37 min.) : color, sound).
- Summary
-
- Contents: Why use drosophila to study immunity?
- Drosophila digestive tract
- Intestinal barriers against pathogens
- The imd pathway in preventing infection
- Serratia marcescens, an opportunistic pathogen
- Genome wide RNA-I screening to identify essential genes for host defense
- Gene ontology of the hits from RNA-I screening
- The JAK/STAT pathway
- The components of host defenses to infections
- Serratia hemolysins.
38. Imaging of small bowel, colon and rectum [2014]
- Paolantonio, Pasquale. author.
- Milan : Springer, 2014.
- Description
- Book — online resource (xiii, 182 pages) : illustrations (some color).
- Summary
-
The new series A-Z Notes in Radiological Practice and Reporting provides practical guides for residents and general radiologists, organized alphabetically, primarily according to disease or condition. All booklets are designed so as to cover a large spectrum of topics referring to different anatomical regions of interest. Entries typically include a short description of pathological and clinical characteristics, guidance on selection of the most appropriate imaging technique, a schematic review of potential diagnostic clues, and useful tips and tricks. The present booklet, enriched by illustrations and schemes, is devoted to gastrointestinal imaging. Major topics in CT and MR imaging of the small bowel, colon, rectum, and anus are treated concisely in alphabetical order. For each topic a brief review of clinical features and pathology is presented, followed by a short description of imaging technique and an accurate review of imaging findings and signs which are useful in the differential diagnosis of gastrointestinal disease.
- Online
Medical Library (Lane)
Medical Library (Lane) | Status |
---|---|
Check Lane Library catalog for status | |
SPRINGER | Unknown |
- Boca Raton : CRC Press, [2014]
- Description
- Book — 1 online resource
- Summary
-
- Commensal Intestinal Microbiota and Mucosal Immune System Development and Function Bacterial Imprinting of the Neonatal Immune System: Lessons From Maternal Cells. Interactions of the Intestinal Microbiota with the Epithelial Cells Host Genotype, Environmental Factors and Microbiota Composition Pathogen-Host Cell Interactions at the Intestinal Level: Lessons from Cultured Human Fully-Differentiated Colon Cancer Caco-2 and T84 Epithelial Cell Lines Manipulation of the Host-Cell Pathways by Bacterial Entero-Pathogens Use of Probiotic Cultures in Humans for the Management of Gastrointestinal Infections. Composition of the Dominant Microbiota During Flare-Ups and Remission of IBD Opportunistic Pathogens in IBD, and the Relation with Specific Gene Susceptibilities Opportunistic Pathogens in IBD, the Case of AIEC. Correction of Microbiota Disturbances or Antagonism against Specific Pathogens in IBD Probiotics in IBD That Can Modulate the Pathological Immune/Inflammatory Activation Their Potential Benefits in the Different Phases of the Disease Fecal Microbiota in Patients Receiving Enteral Nutrition How to Preserve a Healthy Intestinal Microbiota in the Intensive Care Patient Dietary Factors, Microbiota in Relation with Overweight and Diabetes.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- Ip, Tony. (University of Massachusetts Medical School, USA) Speaker
- London : Henry Stewart Talks, 2014.
- Description
- Video — 1 online resource (1 streaming video file (34 min.) : color, sound).
- Summary
-
- Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs)
- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration
- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes
- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs
- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division
- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.
- Ip, Tony. (University of Massachusetts Medical School, USA) Speaker
- London : Henry Stewart Talks, 2014.
- Description
- Video — 1 online resource (1 streaming video file (30 min.) : color, sound).
- Summary
-
- Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs)
- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration
- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes
- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs
- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division
- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.
- Choffnes, Eileen R., author.
- Washington, D.C. : National Academies Press, [2014]
- Description
- Book — 1 online resource (1 PDF file (xxv, 521 pages)) : illustrations
- Summary
-
- 1 Front Matter-- 2 Workshop Overview-- 3 A1 Effector and memory T cell responses to commensal bacteria--Yasmine Belkaid, Nicolas Bouladoux, and Timothy W. Hand-- 4 A2 What are the consequences of the disappearing human microbiota?--Martin J. Blaser and Stanley Falkow-- 5 A3 Pathways in microbe-induced obesity--Laura M. Cox and Martin J. Blaser-- 6 A4 Microbial exposure during early life has persistent effects on natural killer T Cell function--Torsten Olszak, Dingding An, Sebastian Zeissig, Miguel Penilla Vera, Julia Richter, Andre Franke, Jonathan N. Glickman, Reiner Siebert, Rebecca M. Barron, Dennis L. Kasper, and Richard S. Blumberg-- 7 A5 The application of ecological theory toward an understanding of the human microbiome--Elizabeth K. Costello, Keaton Stagaman, Les Dethlefsen, Brendan J. M. Bohannan, and David A. Relman-- 8 A6 Seasonal restructuring of the ground squirrel gutmicrobiota over the annual hibernation cycle--Hannah V. Carey, William A. Walters, and Rob Knight-- 9 A7 Lessons from studying insect symbioses--Angela E. Douglas-- 10 A8 A new vision of immunity: homeostasis of the superorganism--Grard Eberl-- 11 A9 Host defense and immunomodulation of mucosal candidiasis--Paul L. Fidel, Jr., and Mairi C. Noverr-- 12 A10 Microbiota-targeted therapies: An ecological perspective--Katherine P. Lemon, Gary C. Armitage, David A. Relman, and Michael Fischbach-- 13 A11 Community ecology and the vaginal microbiome--Larry J. Forney and Jacques Ravel-- 14 A12 Investigating bacterial-animal symbioses with light sheet microscopy--Michael J. Taormina, Matthew Jemielita, W. Zac Stephens, Adam R. Burns, Joshua V. Troll, Raghuveer Parthasarathy, and Karen Guillemin-- 15 A13 Clinical application of fecal microbiota transplantation in Clostridium difficile infection and beyond--Josbert J. Keller and Els van Nood-- 16 A14 Consumption of human milk glycoconjugates by infant-associated bifidobacteria: Mechanisms and implications--Daniel Garrido, David C. Dallas, and David A. Mills-- 17 A15 Bacteriophage adhering to mucus providea nonhost-derived immunity--Jeremy J. Barr, Rita Auro, Mike Furlan, Katrine L. Whiteson, Marcella L. Erb, Joe Pogliano, Aleksandr Stotland, Roland Wolkowicz, Andrew S. Cutting, Kelly S. Doran, Peter Salamon, Merry Youle, and Forest Rohwer-- 18 A16 Topographic diversity of fungal and bacterial communities in human skin--Keisha Findley, Julia Oh, Joy Yang, Sean Conlan, Clayton Deming, Jennifer A. Meyer, Deborah Schoenfeld, Effie Nomicos, Morgan Park, NIH Intramural Sequencing Center Comparative Sequencing Program, Heidi H. Kong, and Julia A. Segre-- 19 A17 Distinct microbial communities within the endosphere and rhizosphere of Populus deltoides roots across contrasting soil types--Neil R. Gottel, Hector F. Castro, Marilyn Kerley, Zamin Yang, Dale A. Pelletier, Mircea Podar, Tatiana Karpinets, Ed Uberbacher, Gerald A. Tuskan, Rytas Vilgalys, Mitchel J. Doktycz, and Christopher W. Schadt-- 20 A18 Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis--Iliyan D. Iliev, Vincent A. Funari, Kent D. Taylor, Quoclinh Nguyen, Christopher N. Reyes, Samuel P. Strom, Jordan Brown, Courtney A. Becker, Phillip R. Fleshner, Marla Dubinsky, Jerome I. Rotter, Hanlin L. Wang, Dermot P. B. McGovern, Gordon D. Brown, and David M. Underhill-- 21 A19 Metagenomics and personalized medicine--Herbert W. Virgin and John A. Todd-- 22 A20 From genetics of inflammatory bowel disease towards mechanistic insights--Daniel B. Graham and Ramnik J. Xavier-- 23 A21 Antimicrobial peptides and the microbiome--Michael Zasloff-- 24 Appendix B: Agenda-- 25 Appendix C: Acronyms-- 26 Appendix D: Glossary-- 27 Appendix E: Speaker Biographies.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
- New York, NY : Springer, 2014.
- Description
- Book — xviii, 436 pages : illustrations (some color) ; 25 cm
- Summary
-
- Part 1. Basic concepts underlying the microbiota-gut-brain axis. Microbial endocrinology and the microbiota-gut-brain axis / Mark Lyte
- Utilizing "omics" tools to study the complex gut ecosystem / Anthony Fodor
- The enteric nervous system and gastrointestinal innervation: integrated local and central control / John B. Furness, Brid P. Callaghan, Leni R. Rivera, and Hyun-Jung Cho
- Intestinal barrier function and the brain-gut axis / Carmen Alonso, María Vicario, Marc Pigrau, Beatriz Lobo, and Javier Santos
- Vagal pathways for microbiome-brain-gut axis communication / Paul Forsythe, John Bienenstock, and Wolfgang A. Kunze
- The brain-gut axis in health and disease / Yasser Al Omran and Qasim Aziz
- part 2. Mechanistic factors influencing the microbiota-gut-brain axis. Gastrointestinal hormones and their targets / Jens F. Rehfeld
- Microbiome, HPA axis and production of endocrine hormones in the gut / Nobuyuki Sudo
- Neuropeptides and the microbiota-gut-brain axis / Peter Holzer and Aitak Farzi
- Bacterial neuroactive compounds produced by psychobiotics / Rebecca Wall, John F. Cryan, R. Paul Ross, Gerald F. Fitzgerald, Timothy G. Dinand, and Catherine Stanton
- Multidirectional chemical signalling between mammalian hosts, resident microbiota, and invasive pathogens: neuroendocrine hormone-induced changes in bacterial gene expression / Michail H. Karavolos and C.M. Anjam Khan
- Influence of stressor-induced nervous system activation on the intestinal microbiota and the importance for immunomodulation / Michael T. Bailey
- part 3. The microbiota-gut-brain axis in health and disease. The effects of inflammation, infection and antibiotics on the microbiota-gut-brain axis / Premysl Bercik and Stephen M. Collins
- Microbiota, inflammation and obesity / Yolanda Sanz and Angela Moya-Pérez
- Microbiota, immunoregulatory old friends and psychiatric disorders / Graham A.W. Rock, Charles L. Raison, and Christopher A. Lowry
- Microbiota-gut-brain axis and cognitive function / Mélanie G. Gareau
- The impact of microbiota on brain and behavior: mechanisms & therapeutic potential / Yuliya E. Borre, Rachel D. Moloney, Gerard Clarke, Timothy G. Dinan, and John F. Cryan
- Neuroimaging the microbiome-gut-brain axis / Kirsten Tillisch and Jennifer S. Labus
- The future of probiotics for disorders of the brain-gut axis / Eamonn M.M. Quigley and Fergus Shanahan
- Index.
- Online
Medical Library (Lane)
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SPRINGER | Unknown |
- Nestlé Nutrition Workshop (79th : 2013 : New York, N.Y.) Author:
- Basel, Switzerland : Karger ; Vevey, Switzerland : Nestle ́Nutrition Institute, [2014]
- Description
- Book — online resource (xiv, 165 pages)
- Summary
-
- A review of the epidemiology of inflammatory bowel disease with a focus on diet, infections, and antibiotic exposure / Lewis, J.D.
- Current issues in the design of clinical trials in IBD / Feagan, B.G.
- The intestinal microbiota in inflammatory bowel diseases / Sartor, R.B.
- Genetics and innate and adaptive immunity in IBD / Zanello, G.; Kevans, D.; Goethel, A.; Silverberg, M.; Tyler, A.; Croitoru, K.
- Interplay of nutrients and microbial metabolites in intestinal immune homeostasis : differential and common mechanisms of immune regulation in the small bowel and colon / Perrigoue, J.; Das, A.; Mora, J.R.
- Diet, the gut microbiome, and the metabolome in IBD / Wu, G.D.
- Antibiotics, probiotics, and prebiotics in IBD / Bernstein, C.N.
- Fecal microbiota transplantation : an interest in IBD / Kahn, S.A.; Goeppinger, S.R.; Rubin, D.T.
- Enteral nutrition as treatment option for Crohn's disease : in kids only / Ruemmele, F.M.; Pigneur, B.; Garnier-Lenglin, H.
- Effects of exclusive enteral nutrition on bone mass, linear growth, and body composition in children with Crohn's disease / Sylvester, F.A.
- Exclusive enteral nutrition : clues to the pathogenesis of Crohn's disease / Levine, A.
- Current state of the art of medical foods / Blum, S. ; Brito, F.
- IBD therapy : new targets and unmet needs / Colombel, J.-F.
- Online
Medical Library (Lane)
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KARGER | Unknown |
- New York : Nova Science Publishers, Inc., 2013.
- Description
- Book — 1 online resource : illustrations.
- Summary
-
- ANASTOMOSES: TYPES, TECHNIQUES/PROCEDURES, CLINICAL OUTCOMES AND COMPLICATIONS; Library of Congress Cataloging-in-Publication Data; Contents; Preface;
- Chapter I: Bilioenteric Anastomoses; Abstract; Introduction; Indications of Bilioenteric Anastomoses; Types of Anastomoses; Techniques; Complications; Outcome and Follow-Up; References;
- Chapter II: Intestinal Anastomosis Education and Training; Abstract; Introduction; Manually and Stapled Bowel Anastomosis; Training According to Surgical Approach; Intestinal Anastomoses: Need for Laboratory Training; Training Models.
- Training Models as a Mean to Assess AbilityAssessment of Technical Skill Transfer from Simulation Models to the Patient in the Operating Room; References;
- Chapter III: Invaginating Colonic Anastomosis;
- 1. Historical Background;
- 2. Techniques of Colonic Anastomosis;
- 3. Anastomotic Line Protection;
- 4. Animal Models for Colonic Anastomosis;
- 5. Telescoping Anastomosis;
- 6. Further Reading;
- Chapter IV: Expandable Devices for Easier, Quicker and More Efficient Aortic-Prosthesis Anastomosis; Abstract;
- 1. Introduction.
- 2. New Expandable Devices for Easier, Quicker and More Efficient Open Surgery for Large Thoracic or Thoracoabdominal AneurysmsConclusion and Perspectives; References;
- Chapter V: Bowel Anastomosis:Types, Techniques/Procedures, Clinical Outcomes and Complications; Abstract; Introduction; Anastomotic Techniques; Colorectal Anastomosis; Colorectal Anastomotic Complications; References; Index.
46. Conquering irritable bowel syndrome [2013]
- Talley, Nicholas Joseph.
- Second edition. - Shelton, Conn. : People's Medical Publishing House, 2013.
- Description
- Book — 1 online resource (xi, 173 pages) : illustrations
- Summary
-
- What is irritable bowel syndrome?
- Causes and diagnosis of IBS
- Diet and exercise, key helpers in the battle
- The mind-body connection: how we can heal ourselves
- Can I just take a pill? Over-the counter drugs and herbs
- Prescription drug treatments for IBS, evidence for what works
- Defeat IBS: a summary.
(source: Nielsen Book Data)
Online 47. How Toxoplasma gondii crosses anatomical barriers : a study of tachyzoite and sporozoite invasion [2013]
- Poukchanski, Anna.
- May 2013.
- Description
- Book — online resource (xii, 149 pages) : illustrations (some color)
- Summary
-
Toxoplasma gondii is an obligate intracellular parasite. It has extraordinary abilities to infect virtually any warm blooded animal, cross a number of biological barriers (intestine, placenta and blood-brain), and invade any nucleated cell tested thus far in vitro. Chapter 1 provides a general introduction to Toxoplasma gondii and its ability to invade the host cell. Emphasis is placed on biological barriers and molecular mechanism of invasion for the different forms of the parasite. Chapter 2 describes a study of how Toxoplasma crosses the human placenta. Chapter 3 provides an insight as to how Enteric Glial Cells contribute to oral Toxoplasma infection in vivo. Chapter 4 deals with the study of how Toxoplasma sporozoites invade host cells. All research topics shed light on details of how Toxoplasma crosses the anatomical barriers: from the tissue barriers of placenta to infection to the possible immune and barrier functions of Enteric Glial Cells to how Toxoplasma sporozoites invade host cells. Chapter 2 describes experiments demonstrating that Toxoplasma tachyzoites invade the human placenta. These experiments used the human placental explant system to determine where the tachyzoites first invade, how they travel down the anchoring villi, and whether there exist type differences in ability to invade this tissue. This study provided several insights: (i) Toxoplasma tachyzoites are unable to penetrate the syncytium, and invade only the exposed tissue (anchoring villi); (ii) There does not appear to be a significant difference in the ability of different strains to infect the tissue. Chapter 3 addresses the possible role of TGF-[beta] by Enteric Glial Cells (EGCs) in oral Toxoplasma infection. Mice expressing a Dominant Negative TGF-[beta] receptor in EGCs were orally infected with Toxoplasma tissue cysts. At the end of the time trials, mice were sacrificed and their intestines subjected to histological analysis. Experiments did not reveal a clear-cut contribution to the control of inflammation by this cell type to the progress of disease. Chapter 4 examines the function of two paralogues of AMA1 and RON2 that are present exclusively in Toxoplasma sporozoites. Dubbed sporoAMA1 and sporoRON2, respectively, that sporoRON2 and sporoAMA1 form an exclusive pairing, stabilized with unique structural features. Furthermore, pre-treating sporozoites with a C-terminal portion of sporoRON2 (but not generic RON2) inhibits sporozoite invasion. We see sporoRON2 in a different compartment from RON4, suggesting that sporoRON2 functions independently of known moving junction components. These data indicate that sporozoites' host cell invasion is dependent on a novel, stage-specific version of the AMA1-RON2 pairing.
- Also online at
Medical Library (Lane)
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(no call number) | Unknown |
- New York : Nova Biomedical, 2013.
- Description
- Book — 1 online resource (vi, 226 pages) : illustrations (some color).
- Summary
-
- Short Bowel Syndrome: Definition, Incidence, Historical Overview & Etiology-- Survival Outcomes of Pediatric Intestinal Failure Patients & the Cost of Comprehensive Care-- Short Bowel Syndrome: Pathophysiology & Intestinal Adaptation-- Mortality & Morbidity of Short Bowel Syndrome-- Intestinal Failure-Associated Liver Disease-- Management of Short Bowel Syndrome-- Novel Agents in the Treatment of Intestinal Failure: Humoral Factors-- The World Experience of the Pediatric Intestinal Failure Program: Successful Outcomes from Intestinal Rehabilitation-- Bowel-Preserving Surgery for Short Bowel Syndrome-- Intestine Transplantation in Children-- Tissue Engineering & Regenerative Medicine Research Perspectives for Intestinal Failure-- Index.
- (source: Nielsen Book Data)
(source: Nielsen Book Data)
Online 49. The Association of gut microbiota and gut function with health and disease in Bangladeshi children [2012]
- Lin, Audrie.
- Mar. 2012.
- Description
- Book — online resource (xv, 154 pages) : illustrations (some color)
- Summary
-
Overview: 555 million preschool children live in developing countries where malnutrition (undernutrition) is a significant problem. The factors that contribute to this issue are multiple, with two important factors being gut microbiota and gut function. To begin to understand gut microbiota and gut function in a developing country, we performed two parallel studies: in the first study, we characterized the baseline gut microbiota of healthy Bangladeshi children, and in the second study, we investigated the association between household environmental conditions and gut function in Bangladeshi children. The gut microbiota affect nutrient metabolism, immune function, and pathogen resistance. Loss of gut function as occurs in environmental enteropathy (a multifaceted, subclinical intestinal disorder likely derived from repeated episodes of infectious gastroenteritis and chronic inflammation) contributes to malnutrition and growth faltering. It is possible that these processes are interrelated with the gut microbiota serving a critical role in environmental enteropathy. Gut microbiota: Previous studies have focused on the gut microbiota of infants and adults from developed countries, but few have characterized the gut microbiota of people living in developing countries. Furthermore, little is known about the gut microbiota and its variation over time in primary-school-age children and adolescents in either developed or developing countries. In this study, we compared the monthly variation in fecal microbiota composition of healthy children (ages 8--14 years) living in an urban slum in Bangladesh with that of age-matched children from affluent suburban communities in the United States. We analyzed 8,000 near full-length sequences of the small-subunit ribosomal RNA gene (16S rDNA) and over 845,000 pyrosequencing reads spanning the V1-V3 variable region of the 16S rDNA. The distal gut of Bangladeshi children harbored significantly higher microbial diversity than U.S. children, a result validated by the discovery of several novel lineages from various bacterial phyla in the full-length Bangladeshi dataset. Bangladeshi and U.S. children displayed distinct gut microbiota architectures. Moreover, significantly lower month-to-month temporal stability was observed in Bangladeshi children compared to U.S. children. Together, these results suggest that different environmental or genetic variables may affect the microbiota of healthy children in the two countries. Further studies are necessary to investigate the underlying mechanisms of these differences and to incorporate these insights into prevention or treatment of diseases. Gut function: Although poor water quality, sanitation, and hygiene are putative risk factors for environmental enteropathy, there are no studies investigating the relationship of household environmental conditions to environmental enteropathy. We compared levels of environmental enteropathy markers to growth patterns and measured the prevalence of parasitic infections in children living in different levels of environmental cleanliness based on indictors of water, sanitation, and hygiene in their households. We conducted a follow-up study of 119 children (< 4 years old) from an existing cohort, living in rural Bangladesh and divided into two types of households: a 'mitigated household' had good water quality, improved sanitation, and a handwashing station stocked with water and soap, and a 'contaminated household' had poor water quality, and inadequate sanitation and handwashing facilities. We measured anthropometry, intestinal parasitic infection, and the following markers to assess gut function: Lactulose:Mannitol (L:M) ratio, immunoglobulin G endotoxin core antibody (IgG EndoCAb), and total IgG. After adjustment for potential confounding, children from mitigated households had higher height-for-age Z-scores (HAZ), lower L:M ratios, and lower IgG EndoCAb titers than children from contaminated households. The L:M ratio was also strongly associated with HAZ in the cohort. Children living in environmentally mitigated households had lower levels of parasitic infection, improved measures of gut function, and improved growth compared to children living in contaminated environments. These results support the hypothesis that environmental contamination mediated through environmental enteropathy could be a cause of growth faltering in low-income countries. Interpretation: By characterizing the baseline gut microbiota of healthy children living in a developing country and correlating their gut function with household environmental conditions, our work provides a foundation to address the role of the gut microbiota and environmental enteropathy in child health.
- Also online at
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(no call number) | Unknown |
50. Bioscience of microbiota, food and health [2012 - ]
- Tokyo : BMFH Press, ©2012-
- Description
- Journal/Periodical