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1 online resource : illustrations (some color).
  • High-Throughput Approaches to Biomarker Discovery and Challenges of Subsequent Validation.- Mass Spectrometry-Based Lipidomics for Biomarker Research.- Flow Cytometry as Platform for Biomarker Discovery and Clinical Validation.- Pentraxin 3 as Biomarker.- Isoprostanes as Biomarkers of Disease and EarlyBiological Effect.- Fetal Membranes: Potential Source of Preterm Birth Biomarkers.- 1-Hydroxypyrene as a Biomarker for Environmental Health.- Biomarkers of Necrosis and Myocardial Remodeling.- Serum Heat Shock Proteins as Novel Biomarker for Heart.- Failure and Cardiovascular Diseases.- Traditional and Proteomic Biomarkers of Autosomal Dominant.- Polycystic Kidney Disease (ADPKD).- Biomarker for Amyotrophic Lateral Sclerosis.- Biomarkers of Vector Bites: Arthropod Immunogenic Salivary Proteins in Vector-Borne Diseases Control.- Biomarkers of Graft-Versus-Host Disease.
  • (source: Nielsen Book Data)9789400776791 20161114
On an annual basis, over 17 million people die due to cardiovascular disease. This represents a third of all global deaths. The World Health Organisation have identified cardiovascular disease as the leading cause of death worldwide. Although many cardiovascular conditions are preventable, there is a need for accurate characterisation and diagnosis of cardiovascular conditions before, during and after treatments. Much of this characterisation entails the use of biological indicators, i.e biomarkers. Biomarkers in Cardiovascular Disease combines detailed information on different cardiovascular conditions and the concomitant application of conventional, new and emerging biomarkers. It covers the latest knowledge, trends and applications. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.
(source: Nielsen Book Data)9789400776791 20161114
online resource (xvi, 563 pages) : illustrations
  • Computed Tomography: Overview
  • Cardiovascular Computed Tomography: Current and Future Scanning System Design
  • Radiation Safety: Radiation Dosimetry and CT Dose Reduction Techniques
  • Assessment of Cardiovascular Calcium: Interpretation, Prognostic Value, and Relationship to Lipids and Other Cardiovascular Risk Factors
  • Natural History and Impact of Interventions on Coronary Calcium
  • The Aorta and Great Vessels
  • Methodology for CCTA Image Acquisition
  • Post processing and Reconstruction Techniques for the Coronary Arteries
  • CTA Large Scale Trials
  • Coronary CT Angiography: Native Vessels
  • Coronary Angiography After Revascularization
  • Assessment of Cardiac Structure and Function by Computed Tomography Angiography
  • Perfusion and Delayed Enhancement Imaging
  • Pericardial/Myocardial Disease Processes
  • Computed Tomography Evaluation in Valvular Heart Disease
  • Assessment of Cardiac and Thoracic Masses
  • CT Angiography of the Peripheral Arteries
  • Aortic, Renal, and Carotid CT Angiography
  • Assessment of Pulmonary Vascular Disease
  • Comparative Use of Radionuclide Stress Testing, Coronary Artery Calcium Scanning, and Noninvasive Coronary Angiography for Diagnostic and Prognostic Cardiac Assessment
  • Cardiovascular Magnetic Resonance Imaging: Overview of Clinical Applications
  • Computed Tomographic Angiography in the Assessment of Congenital Heart Disease
  • CT Imaging: Cardiac Electrophysiology Applications
  • An Interventionalist's Perspective: Diagnosis of Cardiovascular Disease
  • CCTA: Cardiothoracic Surgery Applications
  • Cardiac CT in the Emergency Room
  • Orientation and Approach to Cardiovascular Images.
This book collates the current knowledge in cardiovascular CT and presents this in a clinically relevant and practical format appropriate for all who use the modality. The field has experienced continued rapid evolution due to advances in technology, the expanded spectrum of cardiovascular applications and significant growth in published data. As increasing numbers have access to CT scanners, Cardiac CT Imaging: Diagnosis of Cardiovascular Disease, Third Edition provides all the relevant information on the use of this modality. This extensive revision of this well-respected textbook brings the reader up-to-date with the technique, with chapters supplied by an experienced set of contributing authors and representing the full spectrum of cardiac CT. It thus represents an essential purchase for those preparing for board examinations, all training to use this modality, and those already using cardiovascular CT on a day-to-day basis who want to stay current.
Medical Library (Lane)
1 online resource (526 p.) Digital: text file; PDF.
  • Introduction.- Epidemiology of Cardiovascular Disease and Depression.- The risk relationship between depression and CVD during aging.- Mechanisms linking depression to cardiovascular disease: what do epidemiological studies tell us?.- Anxiety and the effects on cardiovascular disease.- A Clinical Cardiology Perspective of Psychocardiology.- The validity of vascular depression as a diagnostic construct.- Mental stress-induced myocardial infarction.- Neuropsychological Impairment of Patients with Depression.- Neuroimaging of risk factors of depression and cardiovascular disease.- Heart Rate Variability, Affective Disorders and Health.- Arterial Stiffness in the depression and cardiovascular comorbidity.- Depression and markers of arteriosclerosis - cross-sectional analyses of the baseline examination of the BiDirect Cohort study.- Metabolic-Inflammation Aspects of Depression and Cardiovascular Disease.- Genetic overlap between depression and cardiovascular disease.- Emotional word processing in cardiovascular disease, depression, and depression subtypes.- Nutrition and depression - current evidence on the association of dietary patterns with depression and its subtypes.- Cardiometabolic Risk and Monitoring in Psychiatric Disorders.- Monitoring for metabolic dysfunction and cardiovascular disease in bipolar disorder: a shared illness process approach.- Assessment and Psychological interventions in depression comorbid with cardiovascular disease.- Moving beyond mood: is it time to recommend cognitive training for depression in older adults?.- The Internet and Mobile technology: a platform for behavior change and intervention in depression and CVDs.- Pharmacological treatment and prevention of cardiovascular diseases and depression comorbidity: understanding epidemiological, clinical trial evidence and the biological underpinnings.- Anti-inflammatory agents for the treatment of depression in the light of comorbid cardiovascular disease.- The use of complementary alternative and integrative medicine (CAIM) for treatment and prevention of late-life depression and cardiovascular disease.- An integrative psychosomatic approach to the treatment of to the treatment of patients with cardiovascular disease.- Prevention of CVD in depression.- Screening for depression in coronary heart disease: detection of early disease states.
  • (source: Nielsen Book Data)9783319324784 20161010
The world is witnessing a burgeoning global epidemic of chronic cerebro- and cardiovascular disease and depression disorders. The reader will find this comprehensive book to be a long-needed, up-to-date knowledge base on these increasingly recognized comorbid conditions that have long-term consequences for individual function and well-being and society in general. This comprehensive book outlines the complex and bidirectional relationship between various types of depression and cerebro- and cardiovascular diseases. It is written by a range of experts in the field, including psychiatrists, cardiologists, neuroscientists, psychologists, and epidemiologists, with the aim of presenting and discussing the most recent evidence on the pathophysiology, neurobiology, and clinical presentation of these common and disabling comorbid conditions and the available pharmacological, psychological, and behavioral interventions. By elucidating the underlying clinical and neurobiological mechanisms in the brain and the rich interplay between the body and the brain biology, the book brings together the latest knowledge of this overlapping area in Psychiatry and Cardiology. The clear descriptions of evidence-based approaches to clinical treatment ensure that it will serve as both an up-to-date overview and a future guide for practicing clinicians and graduate students.
(source: Nielsen Book Data)9783319324784 20161010
online resource (xxv, 622 pages) : illustrations (some color) ; 28 cm
Medical Library (Lane)
1 online resource : illustrations (chiefly color)
  • Anatomic considerations and examination of cardiovascular specimens (excluding devices)
  • Age-related cardiovascular changes and diseases
  • Vascular pathobiology : atherosclerosis and large vessel disease
  • Diseases of small and medium-sized blood vessels
  • Aneurysms of the aorta : ascending, thoracic and abdominal and their management
  • Fundamental principles in cardiovascular genetics
  • Myocardial ischemia and its complications
  • Pathophysiology of heart failure and an overview of therapies
  • Myocarditis
  • Pathology of sudden death, cardiac arrhythmias and conduction system
  • Cardiomyopathies
  • Valvular heart disease
  • Cardiac valve replacement and related interventions
  • The pathology of cardiovascular interventions and devices for coronary artery disease, vascular disease, heart failure, and arrhythmias
  • Congenital heart disease : pathology, natural history, and interventions
  • The pericardium and its diseases
  • Pathology of cardiac transplantation
  • Toxins and the heart
  • Tumors of the cardiovascular system : heart and blood vessels
  • Forensic aspects of cardiovascular pathology.
Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. Customers buy the Print + Electronic product together! * Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine* Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications* Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system* Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation.
(source: Nielsen Book Data)9780124202191 20160619
online resource (xv, 798 pages) : illustrations (chiefly color)
  • Anatomic considerations and examination of cardiovascular specimens (excluding devices)
  • Age-related cardiovascular changes and diseases
  • Vascular pathobiology : atherosclerosis and large vessel disease
  • Diseases of small and medium-sized blood vessels
  • Aneurysms of the aorta : ascending, thoracic and abdominal and their management
  • Fundamental principles in cardiovascular genetics
  • Myocardial ischemia and its complications
  • Pathophysiology of heart failure and an overview of therapies
  • Myocarditis
  • Pathology of sudden death, cardiac arrhythmias and conduction system
  • Cardiomyopathies
  • Valvular heart disease
  • Cardiac valve replacement and related interventions
  • The pathology of cardiovascular interventions and devices for coronary artery disease, vascular disease, heart failure, and arrhythmias
  • Congenital heart disease : pathology, natural history, and interventions
  • The pericardium and its diseases
  • Pathology of cardiac transplantation
  • Toxins and the heart
  • Tumors of the cardiovascular system : heart and blood vessels
  • Forensic aspects of cardiovascular pathology.
Medical Library (Lane)
online resource (x, 168 pages) : illustrations (some color)
  • TEE-guided cardioversion
  • Transcatheter aortic valve replacement
  • ASD closure
  • Closure of paravalvular leaks
  • VSD closure
  • Transcatheter repair of the mitral valve
  • LA appendage closure
  • Hypertrophic cardiomyopathy
  • alcohol septal ablation
  • Percutaneous mitral valvotomy
  • Catheter based removal of intracardiac thrombus
  • OCT/IVUS role in coronary interventions
  • Retrieving embolized devices
  • Role of imaging in mechanical circulatory support of the heart.
Medical Library (Lane)
online resource
JACC: Basic to Translational Science, an open access journal, serves as a forum for advancing the field of translational cardiovascular medicine, and as a platform for accelerating the translation of novel scientific discoveries into new therapies that improve clinical outcomes for patients affected with or at risk for cardiovascular disease.
Medical Library (Lane)
online resource (viii, 262 pages) : illustrations
  • Understanding the Complex Circuitry of lncRNAs at the X-inactivation Center and its Implications in Disease Conditions
  • Long Non-coding RNA ANRIL and Polycomb in Human Cancers and Cardiovascular Disease
  • Form and function of exosome associated long non-coding RNAs in cancer
  • Long Non-coding RNAs in Lung Cancer
  • Pseudogene-expressed RNAs: Emerging roles in gene regulation and disease
  • Functional long non-coding RNAs in vascular smooth muscle cells
  • Long Non-coding RNAs as Targets and Regulators of Nuclear Hormone Receptors
  • Non-coding transcriptional landscape in human aging
  • LncRNAs in stress response
  • Expression Specificity of Disease-Associated lncRNAs: towards Personalized Medicine. .
Medical Library (Lane)
online resource : illustrations (some color)
Ideal for cardiologists, surgeons, and referring physicians who need a clinical guide to interventional procedures, Textbook of Interventional Cardiology focuses on the latest treatment protocols for managing heart disorders at every level of complexity. In this updated edition, Dr. Topol continues to bring together experts in the field who present the current state of knowledge and clinical practice in interventional cardiology, including cutting-edge theories, trends, and applications of diagnostic and interventional cardiology, as well as peripheral vascular techniques and practices.
Medical Library (Lane)
online resource (xv, 857 pages) : color illustrations, charts
Written and endorsed by world experts from the American Society of Echocardiography (ASE), this unique multimedia resource uses text, case studies, and online components to cover the latest uses of echocardiography, including the most recent 2D and 3D advances. Unlike other existing textbooks in echocardiography, including the predecessor of this volume, entitled Dynamic Echocardiography, this 2nd edition, with its new title, covers a full range of topics, reflected in its 200 chapters that include essential material in a succinct format. Dr. Roberto M. Lang and his expert colleagues provide everything you need to assess cardiac anatomy and function and obtain clinically useful, noninvasive information for more accurate diagnosis and evaluation of heart disease.
Medical Library (Lane)
online resource (vi, 218 pages) : illustrations (some color)
  • PART I: HEART 1 Electrocardiography
  • 2 Echocardiography
  • 3 New techniques: 3D, CT, MRI
  • PART II: LARGE ARTERIES 4 Ultrasound of Carotid IMT and plaque.- 5 Ultrasound of the Aorta/coronary arteries.- 6 Pulse wave velocity and central BP.- 7 Ankle-brachial index
  • 8 Atherosclerosis and general principles of arterial imaging
  • 9 Imaging and ageing of the aorta and large arteries in the lower extremities
  • PART III: SMALL ARTERIES 10 Micro myography
  • 11 Damage of the retinal arterioles
  • 12 Capillaroscopy
  • 13 Other techniques for assessment
  • PART IV: KIDNEY 14 Proteinuria
  • 15 Glomerular Filtration Rate
  • 16 Other techniques
  • PART V: BRAIN 17 RMN/TC: Evaluation of Brain damage
  • 18 Questionnaires for cognitive function
  • 19 Other techniques for neurological damage.- 20 Relation between blood pressure and markers of organ damage.
This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.
Medical Library (Lane)
online resource (xvii, 277 pages) : illustrations ; 29 cm
  • Anatomy
  • Electrocardiogarphy: normal heart, acute ischemia, and chronic disease
  • Principles of cardiovascular imaging
  • Devices
  • Arrhythmias
  • Vascular disease
  • Cardiomyopathies
  • Pediatric cardiology
  • Procedures.
Medical Library (Lane)
1 online resource (1 streaming video file (35 min.) : color, sound).
  • Contents: Atrial fibrillation: classification
  • Treatment goals and strategies – Traditional and novel anticoagulation: data from clinical trials.
online resource (xiv, 338 pages) : illustrations
  • MRI scanner and coils
  • Signal generation
  • k-space
  • Pulse sequence
  • Image acquisition
  • Image resolution
  • Fast imaging
  • High field MRI (3 Tesla or higher)
  • Artifacts
  • MRI safety
  • Gating
  • Gradient echo and cine imaging
  • Black blood imaging and tissue characterization
  • Perfusion
  • Stress testing
  • Late gadolinium enhancement imaging (scar/fibrosis)
  • Phase contrast flow
  • Coronary imaging
  • Spectroscopy
  • Contrast media
  • Contrast enhanced MRA
  • Non-contrast enhanced MRA
  • Advanced cardiovascular magnetic resonance techniques.
This book is a comprehensive and authoritative text on the subject of cardiovascular magnetic resonance (CMR). Imaging experts from the most medically advanced areas of the world discuss the basic principles of this modality in detail while maintaining a focus on the needs of cardiovascular imagers who wish to learn more about this subject but do not have a strong background in physics. CMR is now considered a clinically important imaging modality for patients with a wide variety of cardiovascular diseases. Recent developments have influenced a wide variety of cardiovascular imaging applications, many of which are now routinely used in clinical practice in CMR laboratories around the world. That it is non-invasive and lacks ionizing radiation exposure make CMR uniquely important for patients whose clinical condition requires serial imaging follow-up. Basic Principles of Cardiovascular MRI: Physics and Imaging Techniques includes a wealth of CMR examples in the form of high-resolution still images. Each imaging technique is discussed in separate chapters that include the physics and clinical applications (with cardiovascular examples) of that particular technique. As such, this book will be essential for cardiovascular medicine specialists and trainees , cardiovascular physicists, and clinical cardiovascular imagers.
Medical Library (Lane)
online resource (x, 165 pages) : color illustrations
  • Inflammation biomarkers and cardiometabolic risk
  • Cardiovascular disease
  • Diabetes mellitus and metabolic syndrome
  • Ischemic stroke
  • Chronic kidney disease
  • Immune-mediated inflammatory rheumatic diseases
  • Cardiometabolic risk, inflammation and neurodegenerative disorders.
Medical Library (Lane)
online resource (xxvii, 1943, 3 pages) : illustrations (chiefly color), color maps
  • Global burden of cardiovascular disease
  • Heart disease in varied populations
  • Ethics in cardiovascular medicine
  • Clinical decision making in cardiology
  • Measurement and improvement of quality of care : relevance to cardiovascular clinical practice
  • Critical evaluation of clinical trials
  • Personalized and precision cardiovascular medicine
  • Principles of cardiovascular genetics
  • Drug therapeutics and personalized medicine
  • Biomarkers, proteomics, metabolomics, and personalized medicine
  • The history and physical examination : an evidence-based approach
  • Electrocardiography
  • Exercise testing
  • Echocardiography
  • The chest radiograph in cardiovascular disease
  • Nuclear cardiology
  • Cardiovascular magnetic resonance imaging
  • Cardiac computed tomography
  • Cardiac catheterization
  • Coronary arteriography and intracoronary imaging
  • Mechanisms of cardiac contraction and relaxation
  • Pathophysiology of heart failure
  • Clinical assessment of heart failure
  • Diagnosis and management of acute heart failure
  • Management of patients with heart failure with reduced ejection fraction
  • Devices for monitoring and managing heart failure
  • Heart failure with a preserved ejection fraction
  • Surgical management of heart failure
  • Mechanical circulatory support
  • Cardiovascular regeneration and gene therapy
  • Care of patients with end-stage heart disease
  • Genetics of cardiac arrhythmias
  • Genesis of cardiac arrhythmias : electrophysiologic considerations
  • Diagnosis of cardiac arrhythmias
  • Therapy for cardiac arrhythmias
  • Pacemakers and implantable cardioverter-defibrillators
  • Specific arrhythmias : diagnosis and treatment
  • Atrial fibrillation : clinical features, mechanisms, and management
  • Cardiac arrest and sudden cardiac death
  • Hypotension and syncope
  • The vascular biology of atherosclerosis
  • Risk markers and the primary prevention of cardiovascular disease
  • Systemic hypertension : mechanisms and diagnosis
  • Systemic hypertension : management
  • Lipoprotein disorders and cardiovascular disease
  • Nutrition and cardiovascular and metabolic diseases
  • Exercise-based, comprehensive cardiac rehabilitation
  • Integrative approaches to the management of patients with heart disease
  • Coronary blood flow and myocardial ischemia
  • Approach to the patient with chest pain
  • ST-elevation myocardial infarction : pathology, pathophysiology, and clinical features
  • ST-elevation myocardial infarction : management
  • Non-ST elevation acute coronary syndromes
  • Stable ischemic heart disease
  • Percutaneous coronary intervention
  • Transcatheter therapies for structural heart disease in adults
  • Diseases of the aorta
  • Peripheral artery diseases
  • Prevention and management of ischemic stroke
  • Treatment of noncoronary obstructive vascular disease
  • Diabetes and the cardiovascular system
  • Congenital heart disease
  • Valvular heart disease
  • Cardiovascular infections
  • The dilated, restrictive, and infiltrative cardiomyopathies
  • Hypertrophic cardiomyopathy
  • Myocarditis
  • Chemical cardiomyopathies
  • Cardiovascular complications of cancer therapeutic agents
  • Cardiovascular abnormalities in HIV-infected individuals
  • Pericardial diseases
  • Traumatic heart disease
  • Pulmonary embolism
  • Pulmonary hypertension
  • Sleep apnea and cardiovascular disease
  • Cardiovascular disease in the elderly
  • Cardiovascular disease in women
  • Pregnancy and heart disease
  • Exercise and sports cardiology
  • Anesthesia and noncardiac surgery in patients with heart disease
  • Endocrine disorders and cardiovascular disease
  • Hemostasis, thrombosis, fibrinolysis, and cardiovascular disease
  • Rheumatic fever
  • Rheumatic diseases and the cardiovascular system
  • Tumors affecting the cardiovascular system
  • Psychiatric and behavioral aspects of cardiovascular disease
  • Neurologic disorders and cardiovascular disease
  • Interface between renal disease and cardiovascular illness
  • Cardiovascular manifestations of autonomic disorders.
Medical Library (Lane)
online resource
Medical Library (Lane)

19. Cardiomyocytes [2015]

online resource (x, 216 pages) : illustrations (some color)
  • Generating primary cultures of murine cardiac myocytes and cardiac fibroblasts to study viral myocarditis / Barbara Sherry
  • Enrichment of cardiomyocytes in primary cultures of murine neonatal hearts / Sreejit Parameswaran ... [et al.]
  • Deep sequencing of cardiac microRNA-mRNA interactomes in clinical and experimental cardiomyopathy / Scot J. Matkovich and Gerald W. Dorn II
  • Next-generation sequencing technology in the genetics of cardiovascular disease / Cecilia Vecoli
  • Computational cardiac electrophysiology : implementing mathematical models of cardiomyocytes to Simulate Action Potentials of the Heart / Michael M. Bell and Elizabeth M. Cherry
  • Methods of myofibrillogenesis modeling / Nancy K. Drew and Anna Grosberg
  • Using the mechanical bidomain model to analyze the biomechanical behavior of cardiomyocytes / Bradley J. Roth
  • Fabrication of a myocardial patch with cells differentiated from human-induced pluripotent stem cells / Lei Ye, Joydeep Basu, and Jianyi Zhang
  • Efficient differentiation of cardiomyocytes from human pluripotent stem cells with growth factors / Rajneesh Jha, Ren-He Xu, and Chunhui Xu
  • Isolation, culturing, and characterization of cardiac muscle cells from nonhuman primate heart tissue / Steven M. Hoynowski and John W. Ludlow
  • Mouse embryonic stem cell-derived cardiac myocytes in a cell culture dish / Carley Glass ... [et al.]
  • Cryopreservation of neonatal cardiomyocytes / Adam C. Vandergriff, M. Taylor Hensley, and Ke Cheng
  • Evaluation of sarcomeric organization in human pluripotent stem cell-derived cardiomyocytes / Chrishan J.A. Ramachandra and Winston Shim
  • Electrotonic coupled metabolic purification of chick cardiomyocytes / Winston Shim
  • Gene transfer into cardiac myocytes / Sarah E. Lang and Margaret V. Westfall
  • Analysis of 4D myocardial wall motion during early stages of chick heart development / Madeline Midgett and Sandra Rugonyi.
This volume has been assembled for scientists interested in basic and applied biomedical research directed toward understanding the development, genetics, and function of cardiomyocytes. The methods and protocols contained within it address cell culture techniques, cardiomyocyte differentiation and redifferentiation, experimental induction of cardiomyopathies, introducing genes into cardiomyocytes, genomic approaches to the understanding cardiomyocytes, cryopreservation of neonatal cardiomyocytes, and modeling of cardiomyocyte function. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and current, Cardiomyocytes: Methods and Protocols explores complimentary areas of cardiomyocyte science that, taken together, can inform individuals with a broad range of interests.
Medical Library (Lane)
online resource (xiii, 234 pages) : illustrations.
This book provides a comprehensive overview of the clinical challenges faced during the treatment of patients with cardiorenal syndrome (CRS). The bidirectional link that associates renal and cardiovascular diseases means that patients with CRS have an increased risk of hospital admission and mortality as a result of their coexistence yet, there are no agreed guidelines for their management. Cardio-Renal Clinical Challenges takes clinical presentations and clinical problems as its base, and then discusses the evidence for best management of common clinical problems and the reasons for the complex interplay between the cardiac and renal systems. In addition, the link between heart failure and chronic kidney disease (CKD) can impose a considerable epidemiological burden thus this text also aims to address the issue of organizing healthcare to maximize both the opportunities for prevention and best healthcare economic returns. This book will be of immediate value and practical interest to all consulting and trainee cardiologists and renal physicians.
Medical Library (Lane)