- Software/Multimedia
- 1 online resource (707 p.) : ill. (some col.), col. charts
"As cities continue to play an increasingly significant role in driving economic growth in many countries, competition among cities have shifted from the national level to the global arena. In this context, international benchmarks for cities are vital for businesses and individuals to make informed decisions. In particular, cost of living, wages and purchasing power are of great interest to employees, employers, multinational corporations and policy-makers as basic indicators tracking urban living standards. This publication by the Asia Competitiveness Institute (ACI) provides annual indices and rankings for cost of living for expatriates as well as indices and rankings for cost of living, wages and purchasing power for ordinary residents in 103 global cities since 2005. The ACI's study reflects salient differences in costs of living for expatriate and ordinary urban dwellers which arise from variations in their lifestyles and consumption preferences. This is of critical significance as cost of living for the former is usually conflated as that for the latter by the general public. In this book, we also delve into the analysis of the nexus between liveability, cost of living and purchasing power. We outline the trends and patterns of these benchmarks and explore if there are trade-offs between liveability and affordability. The ACI's study has received considerable interest from reputable media outlets such as the British Broadcasting Corporation (BBC) and the Edge Malaysia."-- Provided by publisher.
"As cities continue to play an increasingly significant role in driving economic growth in many countries, competition among cities have shifted from the national level to the global arena. In this context, international benchmarks for cities are vital for businesses and individuals to make informed decisions. In particular, cost of living, wages and purchasing power are of great interest to employees, employers, multinational corporations and policy-makers as basic indicators tracking urban living standards. This publication by the Asia Competitiveness Institute (ACI) provides annual indices and rankings for cost of living for expatriates as well as indices and rankings for cost of living, wages and purchasing power for ordinary residents in 103 global cities since 2005. The ACI's study reflects salient differences in costs of living for expatriate and ordinary urban dwellers which arise from variations in their lifestyles and consumption preferences. This is of critical significance as cost of living for the former is usually conflated as that for the latter by the general public. In this book, we also delve into the analysis of the nexus between liveability, cost of living and purchasing power. We outline the trends and patterns of these benchmarks and explore if there are trade-offs between liveability and affordability. The ACI's study has received considerable interest from reputable media outlets such as the British Broadcasting Corporation (BBC) and the Edge Malaysia."-- Provided by publisher.
- Software/Multimedia
- 1 online resource (202 p.) : col. ill., col. maps.
"An underpinning force in Singapore's remarkable 50-year transformation into a sophisticated world-class city, engineering has contributed significantly to the nation's economic, infrastructural and social developments. A joint publication by The Institution of Engineers, Singapore, and World Scientific Publishing, to celebrate Singapore's 50th birthday, 50 Years of Engineering in Singapore brings to life the extraordinary engineering feats across multiple disciplines and tells the stories of these exceptional engineers who, with their determinations and courage, turned the little red dot into a jewel of a city. A vibrant record of engineering excellence, the publication traces the goliath challenges impeding the nation's growth over the past five decades, and the engineering innovations that brought about wealth creation, higher standards of living, and enhanced liveability. This compendium covers land transportation (ERP system, MRT and LRT, roads and buses system); water management and engineering; energy (supply and maintenance); manufacturing in the areas of electronics, precision engineering, chemical and pharmaceutical/bio-medical engineering; housing/cities/infrastructure and land use (reclamation and underground); air and sea hub; and telecommunications, ICT and software."-- Provided by publisher.
"An underpinning force in Singapore's remarkable 50-year transformation into a sophisticated world-class city, engineering has contributed significantly to the nation's economic, infrastructural and social developments. A joint publication by The Institution of Engineers, Singapore, and World Scientific Publishing, to celebrate Singapore's 50th birthday, 50 Years of Engineering in Singapore brings to life the extraordinary engineering feats across multiple disciplines and tells the stories of these exceptional engineers who, with their determinations and courage, turned the little red dot into a jewel of a city. A vibrant record of engineering excellence, the publication traces the goliath challenges impeding the nation's growth over the past five decades, and the engineering innovations that brought about wealth creation, higher standards of living, and enhanced liveability. This compendium covers land transportation (ERP system, MRT and LRT, roads and buses system); water management and engineering; energy (supply and maintenance); manufacturing in the areas of electronics, precision engineering, chemical and pharmaceutical/bio-medical engineering; housing/cities/infrastructure and land use (reclamation and underground); air and sea hub; and telecommunications, ICT and software."-- Provided by publisher.
- Software/Multimedia
- 1 online resource (302 p.) : ill.
"The book presents a theory of abstract duality pairs which arises by replacing the scalar field by an Abelian topological group in the theory of dual pair of vector spaces. Examples of abstract duality pairs are vector valued series, spaces of vector valued measures, spaces of vector valued integrable functions, spaces of linear operators and vector valued sequence spaces. These examples give rise to numerous applications such as abstract versions of the Orlicz–Pettis Theorem on subseries convergent series, the Uniform Boundedness Principle, the Banach–Steinhaus Theorem, the Nikodym Convergence theorems and the Vitali–Hahn–Saks Theorem from measure theory and the Hahn–Schur Theorem from summability. There are no books on the current market which cover the material in this book. Readers will find interesting functional analysis and the many applications to various topics in real analysis."-- Provided by publisher.
"The book presents a theory of abstract duality pairs which arises by replacing the scalar field by an Abelian topological group in the theory of dual pair of vector spaces. Examples of abstract duality pairs are vector valued series, spaces of vector valued measures, spaces of vector valued integrable functions, spaces of linear operators and vector valued sequence spaces. These examples give rise to numerous applications such as abstract versions of the Orlicz–Pettis Theorem on subseries convergent series, the Uniform Boundedness Principle, the Banach–Steinhaus Theorem, the Nikodym Convergence theorems and the Vitali–Hahn–Saks Theorem from measure theory and the Hahn–Schur Theorem from summability. There are no books on the current market which cover the material in this book. Readers will find interesting functional analysis and the many applications to various topics in real analysis."-- Provided by publisher.
4. Advanced green chemistry [electronic resource]. Part 1, Greener organic reactions and processes [2018]
- Software/Multimedia
- 1 online resource (302 p.) : ill. (some col.)
"Green Chemistry has evolved in response to several environmental issues in the second half of the last century, mostly due to the almost freely expanding chemical, petrochemical, and pharmaceutical industries. During the past two decades Green Chemistry grew rapidly and we can now consider this area as a mature and powerful field. Tremendous development has taken place in many important areas including renewable energy and resources, reaction environments, catalysis, synthesis, chemical biology, green materials, in situ monitoring and facile recycling. The combination of Green Chemistry with engineering, biology, toxicology, and physics will lead to novel interdisciplinary systems, which can now lift Green Chemistry to the next, advanced level. The editors of this book have assembled as authors among the best specialists of this growing area of research. This collection of reviews and perspectives provides an exciting vision of the more recent developments in Green Chemistry. It illustrates the breath of the field and its role to address environmental issues. This volume will serve as a book of reference showing a panoramic view of the field and a preview of its future direction as well as a book of inspiration for those aiming to further advance its frontiers."-- Provided by publisher.
"Green Chemistry has evolved in response to several environmental issues in the second half of the last century, mostly due to the almost freely expanding chemical, petrochemical, and pharmaceutical industries. During the past two decades Green Chemistry grew rapidly and we can now consider this area as a mature and powerful field. Tremendous development has taken place in many important areas including renewable energy and resources, reaction environments, catalysis, synthesis, chemical biology, green materials, in situ monitoring and facile recycling. The combination of Green Chemistry with engineering, biology, toxicology, and physics will lead to novel interdisciplinary systems, which can now lift Green Chemistry to the next, advanced level. The editors of this book have assembled as authors among the best specialists of this growing area of research. This collection of reviews and perspectives provides an exciting vision of the more recent developments in Green Chemistry. It illustrates the breath of the field and its role to address environmental issues. This volume will serve as a book of reference showing a panoramic view of the field and a preview of its future direction as well as a book of inspiration for those aiming to further advance its frontiers."-- Provided by publisher.
- Software/Multimedia
- 1 online resource (893 p.) : ill.
"This book provides a comprehensive introduction to Fock space theory and its applications to mathematical quantum field theory. The first half of the book, Part I, is devoted to detailed descriptions of analysis on abstract Fock spaces (full Fock space, boson Fock space, fermion Fock space and boson-fermion Fock space). It includes the mathematics of second quantization, representation theory of canonical commutation relations and canonical anti-commutation relations, Bogoliubov transformations, infinite-dimensional Dirac operators and supersymmetric quantum field in an abstract form. The second half of the book, Part II, covers applications of the mathematical theories in Part I to quantum field theory. Four kinds of free quantum fields are constructed and detailed analyses are made. A simple interacting quantum field model, called the van Hove model, is fully analyzed in an abstract form. Moreover, a list of interacting quantum field models is presented and a short description to each model is given. To graduate students in mathematics or physics who are interested in the mathematical aspects of quantum field theory, this book is a good introductory text. It is also well suited for self-study and will provide readers a firm foundation of knowledge and mathematical techniques for reading more advanced books and current research articles in the field of mathematical analysis on quantum fields. Also, numerous problems are added to aid readers to develop a deeper understanding of the field."-- Provided by publisher.
"This book provides a comprehensive introduction to Fock space theory and its applications to mathematical quantum field theory. The first half of the book, Part I, is devoted to detailed descriptions of analysis on abstract Fock spaces (full Fock space, boson Fock space, fermion Fock space and boson-fermion Fock space). It includes the mathematics of second quantization, representation theory of canonical commutation relations and canonical anti-commutation relations, Bogoliubov transformations, infinite-dimensional Dirac operators and supersymmetric quantum field in an abstract form. The second half of the book, Part II, covers applications of the mathematical theories in Part I to quantum field theory. Four kinds of free quantum fields are constructed and detailed analyses are made. A simple interacting quantum field model, called the van Hove model, is fully analyzed in an abstract form. Moreover, a list of interacting quantum field models is presented and a short description to each model is given. To graduate students in mathematics or physics who are interested in the mathematical aspects of quantum field theory, this book is a good introductory text. It is also well suited for self-study and will provide readers a firm foundation of knowledge and mathematical techniques for reading more advanced books and current research articles in the field of mathematical analysis on quantum fields. Also, numerous problems are added to aid readers to develop a deeper understanding of the field."-- Provided by publisher.
6. Anticipated burden and mitigation of carbon dioxide-induced nutritional deficiencies and related diseases: A simulation modeling study [2018] Online
Background
Rising atmospheric carbon dioxide concentrations are anticipated to decrease the zinc and iron concentrations of crops. The associated disease burden, and optimal mitigation strategies, remain unknown. We sought to understand where and to what extent increasing carbon dioxide concentrations may increase the global burden of nutritional deficiencies through changes in crop nutrient concentrations, and the effects of potential mitigation strategies.
Methods and Findings
For each of 137 countries, we incorporated estimates of climate change, crop nutrient concentrations, dietary patterns, and disease risk into a microsimulation model of zinc and iron deficiency. These estimates were obtained from the Intergovernmental Panel on Climate Change, U.S. Department of Agriculture, Food and Agriculture Organization of the United Nations Statistics Division, and Global Burden of Disease Project, respectively. In the absence of increasing carbon dioxide concentrations, we estimated that zinc and iron deficiencies would induce 1072.9 million disability-adjusted life-years (DALYs) globally over the period 2015 to 2050 (95% Credible Interval (CrI): 971.1 to 1167.7). In the presence of increasing carbon dioxide concentrations, we estimated that decreasing zinc and iron concentrations of crops would induce an additional 125.8 million DALYs globally over the same period (95% CrI: 113.6, 138.9). This carbon dioxide-induced disease burden is projected to disproportionately affect nations in the World Health Organization’s South-East Asian and African regions (44.0 and 28.5 million DALYs, respectively), which already have high existing disease burdens from zinc and iron deficiencies (364.3 and 299.5 million DALYs, respectively), increasing global nutritional inequalities. Climate mitigation strategies such as the Paris Agreement would be expected to avert 48.2% of this burden (95% CrI: 47.8%, 48.5%), while traditional public health interventions including nutrient supplementation and disease control programs would be expected to avert 26.6% of the burden (95% CrI: 23.8 to 29.6%). Of the traditional public health interventions, zinc supplementation would be expected to avert 5.5%, iron supplementation 15.7%, malaria mitigation 3.2%, diarrhea mitigation 1.6%, and pneumonia mitigation 0.5%. The primary limitations of the analysis include uncertainty regarding how food consumption patterns may change with climate, disease mortality rates will change over time, and crop zinc and iron concentrations will decline from those at present to those in 2050.
Conclusions
Effects of increased carbon dioxide on crop nutrient concentrations are anticipated to exacerbate inequalities in zinc and iron deficiencies by 2050. Proposed Paris Agreement strategies are expected to be more effective than traditional public health measures to avert the increased inequality.
Background
Rising atmospheric carbon dioxide concentrations are anticipated to decrease the zinc and iron concentrations of crops. The associated disease burden, and optimal mitigation strategies, remain unknown. We sought to understand where and to what extent increasing carbon dioxide concentrations may increase the global burden of nutritional deficiencies through changes in crop nutrient concentrations, and the effects of potential mitigation strategies.
Methods and Findings
For each of 137 countries, we incorporated estimates of climate change, crop nutrient concentrations, dietary patterns, and disease risk into a microsimulation model of zinc and iron deficiency. These estimates were obtained from the Intergovernmental Panel on Climate Change, U.S. Department of Agriculture, Food and Agriculture Organization of the United Nations Statistics Division, and Global Burden of Disease Project, respectively. In the absence of increasing carbon dioxide concentrations, we estimated that zinc and iron deficiencies would induce 1072.9 million disability-adjusted life-years (DALYs) globally over the period 2015 to 2050 (95% Credible Interval (CrI): 971.1 to 1167.7). In the presence of increasing carbon dioxide concentrations, we estimated that decreasing zinc and iron concentrations of crops would induce an additional 125.8 million DALYs globally over the same period (95% CrI: 113.6, 138.9). This carbon dioxide-induced disease burden is projected to disproportionately affect nations in the World Health Organization’s South-East Asian and African regions (44.0 and 28.5 million DALYs, respectively), which already have high existing disease burdens from zinc and iron deficiencies (364.3 and 299.5 million DALYs, respectively), increasing global nutritional inequalities. Climate mitigation strategies such as the Paris Agreement would be expected to avert 48.2% of this burden (95% CrI: 47.8%, 48.5%), while traditional public health interventions including nutrient supplementation and disease control programs would be expected to avert 26.6% of the burden (95% CrI: 23.8 to 29.6%). Of the traditional public health interventions, zinc supplementation would be expected to avert 5.5%, iron supplementation 15.7%, malaria mitigation 3.2%, diarrhea mitigation 1.6%, and pneumonia mitigation 0.5%. The primary limitations of the analysis include uncertainty regarding how food consumption patterns may change with climate, disease mortality rates will change over time, and crop zinc and iron concentrations will decline from those at present to those in 2050.
Conclusions
Effects of increased carbon dioxide on crop nutrient concentrations are anticipated to exacerbate inequalities in zinc and iron deficiencies by 2050. Proposed Paris Agreement strategies are expected to be more effective than traditional public health measures to avert the increased inequality.
- Software/Multimedia
- 1 online resource (346 p.) : ill. (some col).
- Controlled drug release systems : mechanisms and kinetics / M Sanopoulou and K G Papadokostaki
- Membranes for artificial kidney / J Vienken
- Advanced blood purification therapies / O de Beek, I Geremia, D Pavlenko and D Stamatialis
- Membranes for artificial lung and gas exchange applications / F Wiese
- Membranes for bioartificial kidney / N V Chevtchik, P Caetano-Pinto, R Masereeuw and D Stamatialis
- Membrane-based bioartificial liver devices / S Khakpour, H M M Ahmed and L De Bartolo
- Are co-culture approaches able to improve biological functions of membrane-based bioartificial livers? / V Pandolfi, U Pereira, M Dufresne and C Legallais
- Membranes for bioartificial pancreas / K Skryzpek, A van Apelddorn and D Stamatialis
- Health economic evaluation during the translation of medical technologies : involving users in the design of bio-artificial pancreas transplantation scenarios for type i diabetes / M IJzerman, T Wissing and E de Koning
- Membranes for regenerative medicine in clinical applications / G Falvo, D Labate and G Catapano
- Membranes for organs on chips / M P Tibbe, L I Segerink, A D van der Meer, D Stamatialis and A van den Berg.
- Controlled drug release systems : mechanisms and kinetics / M Sanopoulou and K G Papadokostaki
- Membranes for artificial kidney / J Vienken
- Advanced blood purification therapies / O de Beek, I Geremia, D Pavlenko and D Stamatialis
- Membranes for artificial lung and gas exchange applications / F Wiese
- Membranes for bioartificial kidney / N V Chevtchik, P Caetano-Pinto, R Masereeuw and D Stamatialis
- Membrane-based bioartificial liver devices / S Khakpour, H M M Ahmed and L De Bartolo
- Are co-culture approaches able to improve biological functions of membrane-based bioartificial livers? / V Pandolfi, U Pereira, M Dufresne and C Legallais
- Membranes for bioartificial pancreas / K Skryzpek, A van Apelddorn and D Stamatialis
- Health economic evaluation during the translation of medical technologies : involving users in the design of bio-artificial pancreas transplantation scenarios for type i diabetes / M IJzerman, T Wissing and E de Koning
- Membranes for regenerative medicine in clinical applications / G Falvo, D Labate and G Catapano
- Membranes for organs on chips / M P Tibbe, L I Segerink, A D van der Meer, D Stamatialis and A van den Berg.
8. Bridging science and policy implication for managing climate extremes [electronic resource] [2018]
- Software/Multimedia
- 1 online resource (231 p.) : ill. (some col.), col. maps.
- Assessing Seasonal Climate Forecasts Over Africa to Support Decision-Making / Niko Wanders and Eric F Wood
- Variability and Predictability of Climate Linked to Extreme Events / Swadhin Behera
- Subseasonal Prediction of Extreme Weather Events / Bin Wang and Ja-Yeon Moon
- Climate Services: For Informing Decisions and Managing Risk / Neil Plummer, Agata Imielska, Karl Braganza, David Jones, Janita Pahalad, Scott Power, Martin Schweitzer, Andrew Watkins, David Walland and Perry Wiles
- Early Warning, Resilient Infrastructure and Risk Transfer / David P Rogers, Haleh Kootval and Vladimir V Tsirkunov
- Climate Services for Sustainable Development / Mannava V K Sivakumar and Filipe Lucio
- Future Changes of Extreme Weather and Natural Disasters due to Climate Change in Japan and Southeast Asia / Eiichi Nakakita, Yasuto Tachikawa, Tetsuya Takemi, Nobuhito Mori and Kenji Tanaka
- Climate Change and Stream Temperature in the Willamette River Basin: Implications for Fish Habitat / Heejun Chang, Eric Watson and Angela Strecker
- An Integrated Approach for Flood Inundation Modeling on Large Scales / Venkatesh Merwade, Mohammad Adnan Rajib and Zhu Liu
- Service and Research on Seasonal Streamflow Forecasting in Australia / P M Feikema, Q J Wang, S Zhou, D Shin, D E Robertson, A Schepen, J Lerat, J C Bennett, N K Tuteja and D Jayasuriya
- A Holistic Framework to Assess Drought Preparedness / Ximing Cai, Majid Shafiee-Jood, Yan Ge, Sylwia Kokoszka and Tushar Apurv
- Priorities of the WMO Commission for Hydrology in the Context of Water, Climate and Risk Management / Liu Zhiyu
- From Prediction to Scenario Analysis: A Brief Review and Commentary / Bryan C Bates.
- Assessing Seasonal Climate Forecasts Over Africa to Support Decision-Making / Niko Wanders and Eric F Wood
- Variability and Predictability of Climate Linked to Extreme Events / Swadhin Behera
- Subseasonal Prediction of Extreme Weather Events / Bin Wang and Ja-Yeon Moon
- Climate Services: For Informing Decisions and Managing Risk / Neil Plummer, Agata Imielska, Karl Braganza, David Jones, Janita Pahalad, Scott Power, Martin Schweitzer, Andrew Watkins, David Walland and Perry Wiles
- Early Warning, Resilient Infrastructure and Risk Transfer / David P Rogers, Haleh Kootval and Vladimir V Tsirkunov
- Climate Services for Sustainable Development / Mannava V K Sivakumar and Filipe Lucio
- Future Changes of Extreme Weather and Natural Disasters due to Climate Change in Japan and Southeast Asia / Eiichi Nakakita, Yasuto Tachikawa, Tetsuya Takemi, Nobuhito Mori and Kenji Tanaka
- Climate Change and Stream Temperature in the Willamette River Basin: Implications for Fish Habitat / Heejun Chang, Eric Watson and Angela Strecker
- An Integrated Approach for Flood Inundation Modeling on Large Scales / Venkatesh Merwade, Mohammad Adnan Rajib and Zhu Liu
- Service and Research on Seasonal Streamflow Forecasting in Australia / P M Feikema, Q J Wang, S Zhou, D Shin, D E Robertson, A Schepen, J Lerat, J C Bennett, N K Tuteja and D Jayasuriya
- A Holistic Framework to Assess Drought Preparedness / Ximing Cai, Majid Shafiee-Jood, Yan Ge, Sylwia Kokoszka and Tushar Apurv
- Priorities of the WMO Commission for Hydrology in the Context of Water, Climate and Risk Management / Liu Zhiyu
- From Prediction to Scenario Analysis: A Brief Review and Commentary / Bryan C Bates.
9. A brief history of bacteria [electronic resource] : the everlasting game between humans and bacteria [2018]
- Software/Multimedia
- 1 online resource (296 p.) : ill. (some col.)
- Introducing bacteria
- Friend or foe?
- A silent battle in the body
- A history of the hard and difficult war against bacteria
- A protracted tug of war
- Who will be the winner? The war continues.
- Introducing bacteria
- Friend or foe?
- A silent battle in the body
- A history of the hard and difficult war against bacteria
- A protracted tug of war
- Who will be the winner? The war continues.
- Software/Multimedia
- 1 online resource (165 p.) : ill. (some col.)
- Six Common Mistakes in Selling a Business to an Unrelated Third Party
- Six More Common Mistakes in Selling a Business
- Marketing the Business
- Letters of Intent and Due Diligence
- Negotiating Key Sale Terms
- Negotiating Employment and Consulting Agreements
- Avoiding Traps in the Agreement of Sale
- Creating a Professional Advisory Team
- Leveraged Recapitalization
- Selling to Other Family Members and/or Key Employees
- The ESOP Alternative
- Going Public in a Traditional IPO
- The Regulation A Alternative
- Appendix I: IRS Form 8594.
- Six Common Mistakes in Selling a Business to an Unrelated Third Party
- Six More Common Mistakes in Selling a Business
- Marketing the Business
- Letters of Intent and Due Diligence
- Negotiating Key Sale Terms
- Negotiating Employment and Consulting Agreements
- Avoiding Traps in the Agreement of Sale
- Creating a Professional Advisory Team
- Leveraged Recapitalization
- Selling to Other Family Members and/or Key Employees
- The ESOP Alternative
- Going Public in a Traditional IPO
- The Regulation A Alternative
- Appendix I: IRS Form 8594.
11. Cade et al. (2018) JEB, Supplemental Matlab Scripts [2018] Online
- Collection
- Goldbogen Lab
How fast animals move is critical to understanding their energetic requirements, locomotor capacity and foraging performance, yet current methods for measuring speed via animal-attached devices are not universally applicable. Here, we present and evaluate a new method that relates forward speed to the stochastic motion of biologging devices as tag jiggle, the amplitude of the tag vibrations as measured by high sample rate accelerometers, increases exponentially with increasing speed. We successfully tested this method in a flow tank using two types of biologging devices and in situ on wild cetaceans spanning ∼3 to >20 m in length using two types of suction cup-attached tag and two types of dart-attached tag. This technique provides some advantages over other approaches for determining speed as it is device-orientation independent and relies only on a pressure sensor and a high sample rate accelerometer, sensors that are nearly universal across biologging device types.
How fast animals move is critical to understanding their energetic requirements, locomotor capacity and foraging performance, yet current methods for measuring speed via animal-attached devices are not universally applicable. Here, we present and evaluate a new method that relates forward speed to the stochastic motion of biologging devices as tag jiggle, the amplitude of the tag vibrations as measured by high sample rate accelerometers, increases exponentially with increasing speed. We successfully tested this method in a flow tank using two types of biologging devices and in situ on wild cetaceans spanning ∼3 to >20 m in length using two types of suction cup-attached tag and two types of dart-attached tag. This technique provides some advantages over other approaches for determining speed as it is device-orientation independent and relies only on a pressure sensor and a high sample rate accelerometer, sensors that are nearly universal across biologging device types.
- Software/Multimedia
- 1 online resource (358 p.) : ill. (some col).
- Optically modulated theranostic nanoparticles
- Gene therapy treatments for cancer
- Nanocarrier based pulmonarygene delivery for lung cancer: therapeutic and imaging approaches
- Quantitative contrast enhanced ultrasound imaging in cancer therapy
- Multifunctional dendritic nanoparticles as a nanomedicine platform
- Oral drug delivery systems for gastrointestinal cancer therapy
- Cancer therapeutics with light : role of nanoscale and tissue engineering in photodynamic therapy
- Targeted contrast agents for 1h MRI of tumor microenvironment
- Solid lipid nanoparticles and nanostructured lipid carriers as anti-cancer delivery systems for therapy and diagnostics.
- Optically modulated theranostic nanoparticles
- Gene therapy treatments for cancer
- Nanocarrier based pulmonarygene delivery for lung cancer: therapeutic and imaging approaches
- Quantitative contrast enhanced ultrasound imaging in cancer therapy
- Multifunctional dendritic nanoparticles as a nanomedicine platform
- Oral drug delivery systems for gastrointestinal cancer therapy
- Cancer therapeutics with light : role of nanoscale and tissue engineering in photodynamic therapy
- Targeted contrast agents for 1h MRI of tumor microenvironment
- Solid lipid nanoparticles and nanostructured lipid carriers as anti-cancer delivery systems for therapy and diagnostics.
- Software/Multimedia
- 1 online resource (610 p.) : ill. (some col.)
"This book represents the results of 45 years of research on a wide range of topics, including atomic physics, single-molecule enzymology, whole-cell metabolism, physiology, pharmacology, linguistics, semiotics, and cosmology. It describes the first comprehensive molecular theory of the genotype-phenotype coupling based on two key theoretical concepts: (i) the conformon, the conformational wave packet in biopolymers carrying both the free energy and genetic information; and (ii) the intracellular dissipative structures, the chemical concentration waves inside the cell that serve as the immediate drivers of all cell functions. Conformons provide the driving forces for all molecular machines in the cell, and intracellular dissipative structures coordinate intra- and intercellular processes such as gene expression and cell-cell communications. One of the predictions made by the cell language theory (CLT) is that there are two forms of genetic information — the Watson–Crick genes transmitting information in time (identified with DNA), and the Prigoginian genes transmitting information in space (identified with RNA expression profiles). The former is analogous to sheet music or written language and the latter is akin to audio music or spoken language, both being coupled by conformons acting as the analog of the pianist. The new theory of DNA structure and function constructed on the basis of CLT can rationally account for most of the puzzling findings recently unearthed by the ENCODE (Encyclopedia of DNA Elements) project. The Cell Language Theory has important applications in biomedical sciences including drug discovery research and personalized medicine on the one hand and in the mind-body research and consciousness studies on the other."-- Provided by publisher.
"This book represents the results of 45 years of research on a wide range of topics, including atomic physics, single-molecule enzymology, whole-cell metabolism, physiology, pharmacology, linguistics, semiotics, and cosmology. It describes the first comprehensive molecular theory of the genotype-phenotype coupling based on two key theoretical concepts: (i) the conformon, the conformational wave packet in biopolymers carrying both the free energy and genetic information; and (ii) the intracellular dissipative structures, the chemical concentration waves inside the cell that serve as the immediate drivers of all cell functions. Conformons provide the driving forces for all molecular machines in the cell, and intracellular dissipative structures coordinate intra- and intercellular processes such as gene expression and cell-cell communications. One of the predictions made by the cell language theory (CLT) is that there are two forms of genetic information — the Watson–Crick genes transmitting information in time (identified with DNA), and the Prigoginian genes transmitting information in space (identified with RNA expression profiles). The former is analogous to sheet music or written language and the latter is akin to audio music or spoken language, both being coupled by conformons acting as the analog of the pianist. The new theory of DNA structure and function constructed on the basis of CLT can rationally account for most of the puzzling findings recently unearthed by the ENCODE (Encyclopedia of DNA Elements) project. The Cell Language Theory has important applications in biomedical sciences including drug discovery research and personalized medicine on the one hand and in the mind-body research and consciousness studies on the other."-- Provided by publisher.
- Software/Multimedia
- 1 online resource (292 p.) : ill.
"This book contains the most interesting problems from the first 24 years of the "Mathematical Duel", an annual international mathematics competition between the students of four schools: the Gymnázium Mikuláše Koperníka in Bílovec, Czech Republic, the Akademicki Zespół Szkół Ogólnokształcących in Chorzów, Poland, the Bundesrealgymnasium Kepler in Graz, Austria and the Gymnázium Jakuba Škody in Přerov, Czech Republic. The problems are presented by topic, grouped under the headings Geometry, Combinatorics, Number Theory and Algebra, which is typical for olympiad-style competitions. Above all, it is of interest to students preparing for mathematics competitions as well as teachers looking for material to prepare their students, as well as mathematically interested enthusiasts from all walks of life looking for an intellectual challenge."-- Provided by publisher.
"This book contains the most interesting problems from the first 24 years of the "Mathematical Duel", an annual international mathematics competition between the students of four schools: the Gymnázium Mikuláše Koperníka in Bílovec, Czech Republic, the Akademicki Zespół Szkół Ogólnokształcących in Chorzów, Poland, the Bundesrealgymnasium Kepler in Graz, Austria and the Gymnázium Jakuba Škody in Přerov, Czech Republic. The problems are presented by topic, grouped under the headings Geometry, Combinatorics, Number Theory and Algebra, which is typical for olympiad-style competitions. Above all, it is of interest to students preparing for mathematics competitions as well as teachers looking for material to prepare their students, as well as mathematically interested enthusiasts from all walks of life looking for an intellectual challenge."-- Provided by publisher.
- Software/Multimedia
- 1 online resource (467 p.) : ill. (some col.)
- Physiology of blood flow and metabolism
- Models of blood flow and metabolism
- Global control of blood flow
- Local control of perfusion
- Externally-based measurements
- Internally-based measurements
- Global changes in cerebral blood flow and metabolism
- Local changes in cerebral blood flow and metabolism
- Conclusions.
- Physiology of blood flow and metabolism
- Models of blood flow and metabolism
- Global control of blood flow
- Local control of perfusion
- Externally-based measurements
- Internally-based measurements
- Global changes in cerebral blood flow and metabolism
- Local changes in cerebral blood flow and metabolism
- Conclusions.
- Collection
- Stanford Research Data
Multidimensional Scaling (MDS) is a classical technique for embedding data in low dimensions, still in widespread use today. Originally introduced in the 1950's, MDS was not designed with high-dimensional data in mind; while it remains popular with data analysis practitioners, no doubt it should be adapted to the high-dimensional data regime. In this paper we study MDS under modern setting, and specifically, high dimensions and ambient measurement noise. We show that, as the ambient noise level increase, MDS suffers a sharp breakdown that depends on the data dimension and noise level, and derive an explicit formula for this breakdown point in the case of white noise. We then introduce MDS+, an extremely simple variant of MDS, which applies a carefully derived shrinkage nonlinearity to the eigenvalues of the MDS similarity matrix. Under a loss function measuring the embedding quality, MDS+ is the unique asymptotically optimal shrinkage function. We prove that MDS+ offers improved embedding, sometimes significantly so, compared with classical MDS. Furthermore, MDS+ does not require external estimates of the embedding dimension (a famous difficulty in classical MDS), as it calculates the optimal dimension into which the data should be embedded.
Multidimensional Scaling (MDS) is a classical technique for embedding data in low dimensions, still in widespread use today. Originally introduced in the 1950's, MDS was not designed with high-dimensional data in mind; while it remains popular with data analysis practitioners, no doubt it should be adapted to the high-dimensional data regime. In this paper we study MDS under modern setting, and specifically, high dimensions and ambient measurement noise. We show that, as the ambient noise level increase, MDS suffers a sharp breakdown that depends on the data dimension and noise level, and derive an explicit formula for this breakdown point in the case of white noise. We then introduce MDS+, an extremely simple variant of MDS, which applies a carefully derived shrinkage nonlinearity to the eigenvalues of the MDS similarity matrix. Under a loss function measuring the embedding quality, MDS+ is the unique asymptotically optimal shrinkage function. We prove that MDS+ offers improved embedding, sometimes significantly so, compared with classical MDS. Furthermore, MDS+ does not require external estimates of the embedding dimension (a famous difficulty in classical MDS), as it calculates the optimal dimension into which the data should be embedded.
17. Code supplement for "The Noise-Sensitivity Phase Transition in Spectral Group Synchronization Over Compact Groups" [2018] Online
- Collection
- Stanford Research Data
In Group Synchronization, one attempts to find a collection of unknown group elements from noisy measurements of their pairwise differences. Several important problems in vision and data analysis reduce to group synchronization over various compact groups. Spectral Group Synchronization is a commonly used, robust algorithm for solving group synchronization problems, which relies on diagonalization of a block matrix whose blocks are matrix representations of the measured pairwise differences. Assuming uniformly distributed measurement errors, we present a rigorous analysis of the accuracy and noise sensitivity of spectral group synchronization algorithms over any compact group, up to the rounding error. We identify a Baik-Ben Arous-P\'ech\'e type phase transition in the noise level, beyond which spectral group synchronization necessarily fails. Below the phase transition, spectral group synchronization succeeds in recovering the unknown group elements, but its performance deteriorates with the noise level. We provide asymptotically exact formulas for the accuracy of spectral group synchronization below the phase transition, up to the rounding error. We also provide a consistent risk estimate, allowing practitioners to estimate the method's accuracy from available measurements.
In Group Synchronization, one attempts to find a collection of unknown group elements from noisy measurements of their pairwise differences. Several important problems in vision and data analysis reduce to group synchronization over various compact groups. Spectral Group Synchronization is a commonly used, robust algorithm for solving group synchronization problems, which relies on diagonalization of a block matrix whose blocks are matrix representations of the measured pairwise differences. Assuming uniformly distributed measurement errors, we present a rigorous analysis of the accuracy and noise sensitivity of spectral group synchronization algorithms over any compact group, up to the rounding error. We identify a Baik-Ben Arous-P\'ech\'e type phase transition in the noise level, beyond which spectral group synchronization necessarily fails. Below the phase transition, spectral group synchronization succeeds in recovering the unknown group elements, but its performance deteriorates with the noise level. We provide asymptotically exact formulas for the accuracy of spectral group synchronization below the phase transition, up to the rounding error. We also provide a consistent risk estimate, allowing practitioners to estimate the method's accuracy from available measurements.
- Software/Multimedia
- 1 online resource (448 p.) : ill. (some col.)
"This volume consists of introductory lectures on the topics in the new and rapidly developing area of toric homotopy theory, and its applications to the current research in configuration spaces and braids, as well as to more applicable mathematics such as fr-codes and robot motion planning. The book starts intertwining homotopy theoretical and combinatorial ideas within the remits of toric topology and illustrates an attempt to classify in a combinatorial way polytopes known as fullerenes, which are important objects in quantum physics, quantum chemistry and nanotechnology. Toric homotopy theory is then introduced as a further development of toric topology, which describes properties of Davis–Januszkiewicz spaces, moment-angle complexes and their generalizations to polyhedral products. The book also displays the current research on configuration spaces, braids, the theory of limits over the category of presentations and the theory of fr-codes. As an application to robotics, the book surveys topological problems relevant to the motion planning problem of robotics and includes new results and constructions, which enrich the emerging area of topological robotics. The book is at research entry level addressing the core components in homotopy theory and their important applications in the sciences and thus suitable for advanced undergraduate and graduate students."--Publisher's website.
"This volume consists of introductory lectures on the topics in the new and rapidly developing area of toric homotopy theory, and its applications to the current research in configuration spaces and braids, as well as to more applicable mathematics such as fr-codes and robot motion planning. The book starts intertwining homotopy theoretical and combinatorial ideas within the remits of toric topology and illustrates an attempt to classify in a combinatorial way polytopes known as fullerenes, which are important objects in quantum physics, quantum chemistry and nanotechnology. Toric homotopy theory is then introduced as a further development of toric topology, which describes properties of Davis–Januszkiewicz spaces, moment-angle complexes and their generalizations to polyhedral products. The book also displays the current research on configuration spaces, braids, the theory of limits over the category of presentations and the theory of fr-codes. As an application to robotics, the book surveys topological problems relevant to the motion planning problem of robotics and includes new results and constructions, which enrich the emerging area of topological robotics. The book is at research entry level addressing the core components in homotopy theory and their important applications in the sciences and thus suitable for advanced undergraduate and graduate students."--Publisher's website.
19. Conjugated polymers and oligomers [electronic resource] : structural and soft matter aspects [2018]
- Software/Multimedia
- 1 online resource (204 p.) : ill. (some col).
- Chain persistency in macromolecular and supramolecular systems / Katrin Wunderlich, Klaus Müllen and George Fytas
- Structure in thin films of p-conjugated semi-conductors from the perspective of transmission electron microscopy / Martin Brinkmann
- Structuring conjugated polymer and polyelectrolytes through self-assembly / Hugh D. Burrows, Beverly Stewart, Luisa Ramos and Licinia L.G. Justino
- Specific interactions between electroactive conducting polymers and DNA bases / Carlos Alemán and David Zanuy
- Supramolecular assemblies of DNA/conjugated polymers / Jérémie Knoops, Jenifer Rubio-Magnieto, Sébastien Richeter, Sébastien Clément and Mathieu Surin
- High throughput in situ scattering of roll-to-roll coated functional polymer films / Jens Wenzel Andreasen
- High pressure structural studies of conjugated polymers / Matti Knaapila, Mika Torkkeli, Ullrich Scherf and Suchismita Guha.
- Chain persistency in macromolecular and supramolecular systems / Katrin Wunderlich, Klaus Müllen and George Fytas
- Structure in thin films of p-conjugated semi-conductors from the perspective of transmission electron microscopy / Martin Brinkmann
- Structuring conjugated polymer and polyelectrolytes through self-assembly / Hugh D. Burrows, Beverly Stewart, Luisa Ramos and Licinia L.G. Justino
- Specific interactions between electroactive conducting polymers and DNA bases / Carlos Alemán and David Zanuy
- Supramolecular assemblies of DNA/conjugated polymers / Jérémie Knoops, Jenifer Rubio-Magnieto, Sébastien Richeter, Sébastien Clément and Mathieu Surin
- High throughput in situ scattering of roll-to-roll coated functional polymer films / Jens Wenzel Andreasen
- High pressure structural studies of conjugated polymers / Matti Knaapila, Mika Torkkeli, Ullrich Scherf and Suchismita Guha.
20. Cultural patterns and neurocognitive circuits II [electronic resource] : East-West connections [2018]
- Software/Multimedia
- 1 online resource (224 p.) : ill. (some col).
"The contents of this book continues the theme as in the previous volume on cultural patterns and cognitive patterns in the East and West, with special regard to those patterns which are determined by our natural-genetic endownments in contrast to those patterns which are influenced by our cultural ("East-West") influences, and within this context a unique flavour is given to the "good life" aspects of adapting to this global community. The chapters written by leading neuroscientists, give an overarching picture from the elementary organisational principles of the human brain through the basic perceptual and motor functions of the brain to the highest levels of cognition, including aesthetical or moral judgments, with an eye on what can be called "good life" in both Eastern and Western cultures. A unique compilation of state-of-the-art overviews of how the human brain is organised and functions in order to achieve high level of social, moral or aesthetic thoughts across cultures."-- Provided by publisher.
"The contents of this book continues the theme as in the previous volume on cultural patterns and cognitive patterns in the East and West, with special regard to those patterns which are determined by our natural-genetic endownments in contrast to those patterns which are influenced by our cultural ("East-West") influences, and within this context a unique flavour is given to the "good life" aspects of adapting to this global community. The chapters written by leading neuroscientists, give an overarching picture from the elementary organisational principles of the human brain through the basic perceptual and motor functions of the brain to the highest levels of cognition, including aesthetical or moral judgments, with an eye on what can be called "good life" in both Eastern and Western cultures. A unique compilation of state-of-the-art overviews of how the human brain is organised and functions in order to achieve high level of social, moral or aesthetic thoughts across cultures."-- Provided by publisher.
