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Multiple parton scattering and induced parton energy loss are studied in deeply inelastic scattering (DIS) off nuclei. The effect of multiple scattering of a highly off-shell quark and the induced parton energy loss is expressed in terms of the modification to the quark fragmentation functions. The authors derive such modified quark fragmentation functions and their QCD evolution equations in DIS using the generalized factorization of higher twist parton distributions. They consider double-hard and hard-soft parton scattering as well as their interferences in the same framework. The final result, which depends on both the diagonal and off-diagonal twist-four parton distributions in nuclei, demonstrates clearly the Landau-Pomeranchuk-Migdal interference features and predicts a unique nuclear modification of the quark fragmentation functions.

Multiple scattering, modified fragmentation functions and radiative energy loss of a heavy quark propagating in a nuclear medium are investigated in perturbative QCD. Because of the quark mass dependence of the gluon formation time, the medium size dependence of heavy quark energy loss is found to change from a linear to a quadratic form when the initial energy and momentum scale are increased relative to the quark mass. The radiative energy loss is also significantly suppressed relative to a light quark due to the suppression of collinear gluon emission by a heavy quark.

Multiple scattering, induced radiative energy loss and modified fragmentation functions of a heavy quark in nuclear matter are studied within the framework of generalized factorization in perturbative QCD. Modified heavy quark fragmentation functions and energy loss are derived in detail with illustration of the mass dependencies of the Landau-Pomeranchuk-Migdal interference effects and heavy quark energy loss. Due to the quark mass dependence of the gluon formation time, the nuclear size dependencies of nuclear modification of the heavy quark fragmentation function and heavy quark energy loss are found to change from a linear to a quadratic form when the initial energy and momentum scale are increased relative to the quark mass. The radiative energy loss of the heavy quark is also significantly suppressed due to limited cone of gluon radiation imposed by the mass. Medium modification of the heavy quark fragmentation functions is found to be limited to the large z region due to the form of heavy quark fragmentation functions in vacuum.