This study contributes to the theory and practice of how chemical weapons programmers and activity can be evaluated in the context of the international prohibition against their development, production, stockpiling, transfer and use as reflected in the 1993 Chemical Weapons Convention. It presents an application of a hybrid and qualitative variation of Heuer's Analysis of Competing Hypothesis (ARC) directed towards arms control verification and intelligence practice using three case studies: the Soviet Union, Iraq, and suspected at al-Qaeda affiliates. This study is comprehensive and multidisciplinary in approach, rather than reductionist. It draws on a very large array of data as they rate to the technical, military and politico-strategic characteristics of chemical warfare, linking a large number of historical detail with conceptual insight into the nature of chemical warfare and chemical weapons arms control.
1 Historical Milieu. 1.1 Organophosphorus Nerve Agents. 1.2 Blister Agents. 1.3 Sternutator Agents. 1.4 Chemical Weapons Convention (CWC). 1.4.1 Schedule of Chemicals. 1.4.2 Destruction of Chemical Weapons. References.
2 Toxicity of Chemical Warfare Agents and their Degradation Products. 2.1 Organophosphorus Nerve Agent Toxicity. 2.1.1 Toxicity Mechanism - Acetylcholinesterase Inhibition. 2.1.2 Exposure. 2.1.3 Response, Treatment and Prevention. 2.2 Toxicity of Nerve Agent Degradation Products. 2.2.1 Toxicity of GA (Tabun) Degradation Products. 2.2.2 Toxicity of GB (Sarin) Degradation Products. 2.2.3 Toxicity of GD (Soman) Degradation Products. 2.2.4 Toxicity of GF (Cyclosarin) Degradation Products. 2.2.5 Toxicity of VX Degradation Products. 2.3 Toxicity of Blister Agents. 2.4 Toxicity of Sternutator Agents. 2.4.1 Toxicity of Degradation Products of Sternutator Agents. References.
3 Analysis of Chemical Warfare Agents. 3.1 Introduction. 3.2 Minimally Invasive Detection Techniques. 3.3 Separation and Detection Techniques. 3.3.1 Capillary Electrophoresis. 3.3.2 Ion Mobility Spectrometry. 3.3.3 Gas Chromatography (GC)/Gas Chromatography-Mass Spectrometry (GC-MS). 3.3.4 Liquid Chromatography (LC)/Liquid Chromatography-Mass Spectrometry (LC-MS). 3.3.5 Desorption Electrospray Ionization and Direct Analysis in Real Time Mass Spectrometry. References.
This book describes nerve agents and vesicants, their decomposition and their degradation products' chemistry as well as their toxicity including a list of detection techniques of nerve agents and their degradation products. This book will present their history, toxicity, comparison between different sample preparation methods, separation techniques, and detection methods all together in a short, easy to read book, tied together by a single group doing the writing and the editing to assure smooth transition from chapter to chapter, with sufficient Tables and literature references for the reader who looks to further detail.The text will illustrate the pluses and minuses of the various techniques with sufficient references for the reader to obtain extensive detail. (source: Nielsen Book Data) 9780470745878 20160605