Cambridge, UK ; Waltham, MA : Woodhead Pub., c2014.
Book — 1 online resource (xxiv, 477 p.) : ill.
Cover; Biomaterials for Bone Regeneration : Novel Techniques and Applications; Copyright; Contents; Contributor contact details; Woodhead Publishing Series in Biomaterials; Dedication; Foreword; Part I:Materials for bone regeneration; 1:Calcium phosphate cements for bone regeneration; 1.1 Introduction; 1.2 Calcium phosphate cements (CPCs); 1.3 Properties of CPCs; 1.4 Design of a CPC; 1.5 Current clinical applications and unmet clinical needs; 1.6 Conclusions; 1.7 References; 2:Injectable calcium phosphate cements for spinal bone repair; 2.1 Introduction
2.2 Biomaterials used in vertebroplasty: calcium phosphate systems and calcium phosphate cements (CPCs)2.3 Property requirements for bone substitute material; 2.4 Improving the qualities of CPCs; 2.5 Other clinical applications of CPC-based systems; 2.6 Conclusions and future trends; 2.7 References; 3:Hydrogels for bone regeneration; 3.1 Introduction; 3.2 Hydrogels for bone regeneration: an overview; 3.3 Hydrogels as injectable delivery systems for bone regeneration; 3.4 Hydrogels for guided bone regeneration
3.5 Hydrogels as carriers and delivery vehicles for growth factors (GFs) and other biologically active elements3.6 Hydrogels supporting mineralization; 3.7 Conclusions and future trends; 3.8 Acknowledgements; 3.9 References; 4:Combinations of biopolymers and synthetic polymers for bone regeneration; 4.1 Introduction; 4.2 Protein-based materials; 4.3 Polysaccharide-based materials; 4.4 Surface-functionalized synthetic polymers and layered systems; 4.5 Future trends; 4.6 Sources of further information and advice; 4.7 References
5:Applications of shape memory polymers (SMPs) in mechanobiology and bone repair5.1 Introduction; 5.2 Shape memory polymers (SMPs); 5.3 SMP substrates for the study of bone cell mechanobiology; 5.4 SMP substrates for the study of osteogenic differentiation; 5.5 SMP substrates and scaffolds for use as in vitro model systems; 5.6 In vivo scaffolds for bone repair; 5.7 Safety considerations; 5.8 Conclusions; 5.9 Sources of further information and advice; 5.10 References; Part II:Processing, surface modification and evaluation of biomaterials for bone regeneration
6:Photopolymerization-based additive manufacturing for the development of 3D porous scaffolds6.1 Introduction; 6.2 Photopolymerization; 6.3 Natural-based photopolymers; 6.4 Synthetic photopolymers; 6.5 Lithography-based additive manufacturing technologies (AMTs) for the fabrication of scaffolds; 6.6 Recent trends
third strategy in tissue engineering; 6.7 Conclusions; 6.8 Acknowledgements; 6.9 References; 6.10 Appendix: List of abbreviations; 7:Cold plasma surface modification of biodegradable polymer biomaterials; 7.1 Introduction; 7.2 Biodegradable polymers
In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has resulted in an important field of research and a range of technological developments. This book provides a comprehensive review of the biomaterials available and how they can be applied in bone regeneration. In part one, a wide range of materials are discussed, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers and shape memory polymers.