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Book
163 pages : illustrations ; 23 cm
Medical Library (Lane)
Book
ix, 447 p. : ill.
  • Overview.- The mechanobiology and biochemistry in cells subjected to sustained mechanical deformations.- Metabolic transport in chronically loaded soft tissues.- Cell death and damage thresholds in mechanically loaded tissues.- Bioengineering aspects of the microcirculation of wounds and of angiogenesis in healing wounds.- Tissue engineering models of chronic wounds.- Computational models of cellular and molecular processes in chronic wound formation.- Computer models of tissue repair and regeneration.- Biomaterials and tissue engineering approaches for wound repair.- Biomaterials in wound dressing.- Biomaterials for controlled drug delivery in wound repair.- Proteomic approaches to quantify phases of wound healing.
  • (source: Nielsen Book Data)9783642005336 20160528
Pressure-related chronic wounds are an important health concern that affects millions of patients and accumulates billions in annual costs. These wounds may occur when soft tissues are mechanically compressed between bony prominences and a supporting surface. This book gives a complete and quantitative explanation of the mechanobiology which causes chronic wounds. The reviews give an overall picture on all length scales of the phenomenon, starting from musculoskeletal biomechanics to the modeling of soft tissues and their interaction with bones. At the microscopic levels, it thoroughly reviews experiments and modeling of cellular forces and molecular processes that occur during injury and healing, including the integrity of living cells subjected to sustained mechanical forces and deformations. The results allow a complete picture of the tolerance of human tissues to sustained loads, and an understanding of the risk for onset of chronic wounds. Hence, this book is also valuable for all professionals involved in the prevention and treatment of chronic wounds.
(source: Nielsen Book Data)9783642005336 20160528
dx.doi.org SpringerLink
Book
1 online resource (xii, 335 p.) : ill.
  • Part I The Aging of Bone and Etiologies of Fractures 1 Osteobiology of Aging ... 3 Andrew Rosenzweig and Robert J. Pignolo ... 3 Andrew Rosenzweig and Robert J. Pignolo 2 Pathologic Fractures ... 43 Jesse T. Torbert and Richard D. Lackman ... 43 Jesse T. Torbert and Richard D. Lackman 3 Falls ... 55 Amy M. Corcoran and Bruce Kinosian ... 55 Amy M. Corcoran and Bruce Kinosian Part II Perioperative Management 4 Preoperative Assessment of Risk ... 71 Joan Weinryb ... 71 Joan Weinryb 5 Anticoagulation ... 87 Kathleen Walsh and John Bruza ... 87 Kathleen Walsh and John Bruza 6 Prevention and Management of Perioperative Delirium ... 101 Jerry C. Johnson ... 101 Jerry C. Johnson 7 Anesthesia and Postoperative Pain Control ... 115 Jonathan R. Gavrin ... 115 Jonathan R. Gavrin 8 Postoperative Complications ... 145 Jung-Hoon Kim ... 145 Jung-Hoon Kim Contents viii Contents Part III Common Fractures in the Elderly 9 Hand and Wrist Fractures in the Elderly ... 171 Laura C. Wiegand, Atul F. Kamath, Nick D. Pappas, and David J. Bozentka ... 171 Laura C. Wiegand, Atul F. Kamath, Nick D. Pappas, and David J. Bozentka 10 Fractures of the Shoulder and Elbow ... 187 J. Stuart Melvin, Karen Boselli, and G. Russell Huffman ... 187 J. Stuart Melvin, Karen Boselli, and G. Russell Huffman 11 Vertebral Compression Fractures ... 225 Ejovi Ughwanogho and Nader M. Hebela ... 225 Ejovi Ughwanogho and Nader M. Hebela 12 Hip Fractures... 239 Andrew F. Kuntz, Albert O. Gee, Jaimo Ahn, and Samir Mehta ... 239 Andrew F. Kuntz, Albert O. Gee, Jaimo Ahn, and Samir Mehta 13 Fractures of the Distal Femur ... 257 Jesse T. Torbert and John L. Esterhai ... 257 Jesse T. Torbert and John L. Esterhai <14 Tibial Plateau Fractures in the Elderly ... 269 John Alan Scolaro and Gwo-Chin Lee ... 269 John Alan Scolaro and Gwo-Chin Lee Part IV Rehabilitation, Post-fracture Evaluation, and Prevention 15 Rehabilitation ... 285 Keith Baldwin, Derek J. Donegan, and Mary Ann Keenan ... 285 Keith Baldwin, Derek J. Donegan, and Mary Ann Keenan 16 Evaluation of Bone Fragility and Fracture Prevention ... 309 Robert J. Pignolo ... 309 Robert J. Pignolo Index ... 329 ... 329.
  • (source: Nielsen Book Data)9781603274661 20160605
"Fractures in the Elderly: A Guide to Practical Management" provides geriatricians and other medical specialists who provide care for older adults with the vital guidance and most current data and opinions regarding the treatment of elderly patients who sustain a variety of fractures. It also provides orthopedic surgeons with the necessary information and most current data and opinions regarding assessment and management of geriatric conditions that predispose the elderly to fracture, perioperative complications and subsequent functional decline. Each chapter is both readable and appealing not only to geriatricians and orthopedic surgeons but to all clinicians that have contact with elderly patients who have sustained or are at high risk of sustaining a fracture. Emphasis is placed on the fact that although in some cases pre- and post-operative care in elderly fracture patient may proceed as it does in younger individuals, often there are considerations owing to functional status, pre-existing conditions, and age-related physiological declines that require specialized knowledge and alternative approaches. Developed by a group of renowned experts, "Fractures in the Elderly: A Guide to Practical Management" is a major addition to the literature and provides a wealth of specialized knowledge and approaches to care. It is an essential reference for all clinicians who care for older adults as well as fellows and residents in training.
(source: Nielsen Book Data)9781603274661 20160605
dx.doi.org SpringerLink
Book
ix, 210 p. : ill. ; 24 cm.
  • Introduction.- Methods in Trauma-Biomechanics.- Head Injuries.- Spinal Injuries.- Thoracic Injuries.- Abdominal Injuries.- Injuries of the Pelvis and the Lower Extremities.- Injury criteria.- Injuries of the Upper Extremities.- Impairment and injuries resulting from chronic mechanical exposure.
  • (source: Nielsen Book Data)9783540738725 20160528
Trauma biomechanics uses the principles of mechanics to study the response and tolerance level of biological tissues under extreme loading conditions. Through an understanding of mechanical factors that influence the function and structure of human tissues, countermeasures can be developed to alleviate or even eliminate such injuries. "Trauma Biomechanics" surveys a wide variety of topics in injury biomechanics including injury classification, injury mechanisms and injury criteria. Both injuries sustained in automotive accidents and in sports are addressed. The interdisciplinary approach necessary in trauma biomechanics is stressed by showing the span from anatomy for each body region to engineering solutions for protection against injury. Injury tolerance values are listed, either currently in use or proposed by both the U.S. and European countries. Although the book is meant as a first introduction for engineers and medical doctors, sufficient references for scientific research are provided also.
(source: Nielsen Book Data)9783540738725 20160528
Book
xvi, 340 p. ; 24 cm.
  • 1. Introduction: A Primer on Surgical Ethics-- 2. Informed Consent and Disclosure-- A. PAINTED INTO A CORNER: UNEXPECTED COMPLICATIONS IN TREATING A JEHOVAH'S WITNESS-- B. A PATIENT REFUSES CONSENT FOR LIFE-SAVING SURGERY-- C. CONSENT FOR AN INTRAOPERATIVE VIDEO RECORDING-- 3. Professional Self-Regulation-- A. WHAT TO TELL PATIENTS HARMED BY OTHER PHYSICIANS-- B. EYE-WITNESS TO INCOMPETENT SURGERY---- C. MILITARY PHYSICIAN'S ETHICAL RESPONSE TO EVIDENCE OF TORTURE-- 4. Innovation and Research-- A. WHEN DOES CONVENTIONAL SURGERY BECOME RESEARCH?---- B. A SURGEON'S OBLIGATION WHEN PERFORMING NEW PROCEDURES---- C. THE ETHICS OF INNOVATIVE APPROACHES FOR WELL-ESTABLISHED PROCEDURES-- 5. Conflicts of Interest and Conflicts of Commitment-- A. INTENTIONAL OVER-TREATMENT: THE UNMENTIONABLE CONFLICT OF INTEREST-- B. PATIENT RESPONSIBILITIES, FAMILY RESPONSIBILITIES-- C. NON-FINANCIAL CONFLICTS OF INTEREST-- 6. The Ethics of Surgery as a Surgery-- A. ETHICS OF PHYSICIANS' INCOME-- B. ETHICS OF PERSONAL ADVERTISING IN SURGERY-- C. ETHICS OF INSTITUTIONAL MARKETING: THE ROLE OF PHYSICIANS-- 7. Medical Professionalism Challenges: Assaults from Within and Without-- A. GOING PUBLIC WITH AMAZING CASES: FIAT OR FIASCO?-- B. UNPROFESSIONAL BEHAVIOR THAT DISRUPTS: CROSSING THE LINE-- C. MY BROTHER'S KEEPER: ETHICS OF UNCOMPENSATED CARE FOR UNDOCUMENTED IMMIGRANTS-- 8. End-of-Life Issues-- A. FUTILITY AND SURGICAL INTERVENTION-- B. ADVANCED AGE, DEMENTIA, AND AN ABDOMINAL ANEURYSM - INTERVENE?-- C. COMPLYING WITH ADVANCE DIRECTIVES IN THE OR-- D. ABDOMINAL AORTIC ANEURYSM IN A DEATH ROW INMATE-- E. TELLING THE TRUTH ABOUT TERMINAL DISEASES-- F. ARSENIC AND OLD LACE: END OF LIFE CARE IN THE POST-OPERATIVE-- G. TRAINING ON NEWLY DECEASED PATIENTS-- H. WITHDRAWAL OF LIFE-SUSTAINING LOW-BURDEN CARE-- I. PHYSICIAN-ASSISTED SUICIDE: HAS IT COME OF AGE?
  • (source: Nielsen Book Data)9780195321081 20160528
  • CHAPTER 1: INTRODUCTION: A PRIMER ON SURGICAL ETHICS-- CHAPTER 2: INFORMED CONSENT AND DISCLOSURE-- 1. PAINTED INTO A CORNER: UNEXPECTED COMPLICATIONS IN TREATING A JEHOVAH'S WITNESS-- 2. A PATIENT REFUSES CONSENT FOR LIFE-SAVING SURGERY---- 3. CONSENT FOR AN INTRAOPERATIVE VIDEO RECORDING-- CHAPTER 3. PROFESSIONAL SELF-REGULATION-- 11. WHAT TO TELL PATIENTS HARMED BY OTHER PHYSICIANS---- 12. EYE-WITNESS TO INCOMPETENT SURGERY---- 13. MILITARY PHYSICIAN'S ETHICAL RESPONSE TO EVIDENCE OF TORTURE-- CHAPTER 4. INNOVATION AND RESEARCH-- 22. WHEN DOES CONVENTIONAL SURGERY BECOME RESEARCH?-- 23. A SURGEON'S OBLIGATION WHEN PERFORMING NEW PROCEDURES-- 24. THE ETHICS OF INNOVATIVE APPROACHES FOR WELL-ESTABLISHED PROCEDURES-- CHAPTER 5. CONFLICTS OF INTEREST AND CONFLICTS OF COMMITMENT-- 33. INTENTIONAL OVER-TREATMENT: THE UNMENTIONABLE CONFLICT OF INTEREST-- 34. PATIENT RESPONSIBILITIES, FAMILY RESPONSIBILITIES---- 35. NON-FINANCIAL CONFLICTS OF INTEREST-- CHAPTER 6. THE ETHICS OF SURGERY AS A SURGERY-- 44. ETHICS OF PHYSICIANS' INCOME---- 45. ETHICS OF PERSONAL ADVERTISING IN SURGERY-- 46. ETHICS OF INSTITUTIONAL MARKETING: THE ROLE OF PHYSICIANS-- CHAPTER 7. MEDICAL PROFESSIONALISM CHALLENGES: ASSAULTS FROM WITHIN AND WITHOUT-- 56. GOING PUBLIC WITH AMAZING CASES: FIAT OR FIASCO?---- 57. UNPROFESSIONAL BEHAVIOR THAT DISRUPTS: CROSSING THE LINE-- 58. MY BROTHER'S KEEPER: ETHICS OF UNCOMPENSATED CARE FOR UNDOCUMENTED IMMIGRANTS-- CHAPTER 8. END-OF-LIFE ISSUES-- 63. FUTILITY AND SURGICAL INTERVENTION---- 64. ADVANCED AGE, DEMENTIA, AND AN ABDOMINAL ANEURYSM: INTERVENE?-- 65. COMPLYING WITH ADVANCE DIRECTIVES IN THE OR---- 66. ABDOMINAL AORTIC ANEURYSM IN A DEATH ROW INMATE---- 67. TELLING THE TRUTH ABOUT TERMINAL DISEASES---- 68. ARSENIC AND OLD LACE: END OF LIFE CARE IN THE POST-OPERATIVE-- 69. TRAINING ON NEWLY DECEASED PATIENTS---- 70. WITHDRAWAL OF LIFE-SUSTAINING LOW-BURDEN CARE---- 71. PHYSICIAN ASSISTED SUICIDE: HAS IT COME OF AGE?
  • (source: Nielsen Book Data)9780195321098 20160528
Surgical ethics is the application of ethics to issues specific to surgery. This volume provides a collection of clinical case studies representing a wide range of the ethical issues surgeons confront today. It is an excellent text for teaching surgical ethics to surgical residents and medical students and a fascinating read for practicing surgeons. It is intended to engage the reader into participating in evidence-based ethical conflicts. The authors escort us through 71 brief, realistic, and ethically complex problems, offering a series of five possible resolutions to each and guiding us through the relative benefits and weaknesses of the options until a best ethical choice is defended. The volume includes sections on Consent and Disclosure, Self-Regulation, Research and Innovation, Conflicts of Interest, Business Dealings, and End of Life Issues, each with a brief introduction by the authors.
(source: Nielsen Book Data)9780195321081 20160528
SAL1&2 (on-campus shelving)
Book
1 online resource (xix, 226 p.) : ill. (some col.)
  • Preface-- Introduction-- Medical Need of Biomarkers for TBI-- The Role of Advanced MRI Findings as Biomarkers of TBI-- Advances in the Measurement of Mild TBI-- Neurodegradomics and Biomarkers for Concussions-- Ionotropic Glutamate Receptors: Preclinical Research-- Clinical Application of Early Biomarkers for Mild TBI-- Astroglial Proteins as Biomarkers of Intracerebral Hemorrhage-- Novel Biomarkers of Combat TBI-- Utilities of TBI Biomarkers in Various Clinical Settings-- Economic Impact of Biomarkers on TBI Management-- TBI Biomarker Assay Development: Future Trends-- Subject Index.
  • (source: Nielsen Book Data)9781849733892 20160614
Due to injuries sustained in sports and in combat, interest in TBI has never been greater. Biomarkers for Traumatic Brain Injury will fulfil a gap in our understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging. This knowledge will be useful for all researchers and clinicians interested in the biochemical and structural sequelae underpinning clinical manifestations of TBI and help guide appropriate patient management. Current and prospective biomarkers for the assessment of traumatic brain injury (TBI), particularly mild TBI, are examined using a multidisciplinary approach involving biochemistry, molecular biology, and clinical chemistry. The book incorporates presentations from outstanding researchers and clinicians in the area and describes advanced proteomic and degradomic technologies in the development of novel biomarker assays. For practical purposes, the focus of this volume is on detection of blood-based biomarkers to improve diagnostic certainty of mild TBI in conjunction with radiological and clinical findings. It represents contributions from internationally-recognized researchers at the forefront of traumatic brain injury many of whom are recipients of grants and contracts from the United States Department of Defense for research specifically on developing diagnostic tests for TBI. The book will be essential reading for scientists, pharmacologists, chemists, medical and graduate students.
(source: Nielsen Book Data)9781849733892 20160614
Book
xix, 201 pages ; 23 cm
  • Foreword-- Steve Fuller 1. Introduction to the Enhancement Debate 2. The Biomedical Paradigm 3. The Transhumanist Paradigm 4. The Social Paradigm 5. To Enhance or Not to Enhance: Looking Into Deeper Issues 6. A Suggested Approach 7. Conclusions.
  • (source: Nielsen Book Data)9781137402233 20160618
This book provides an overview of the new and emergent technologies that are and will continue to play a central role in the future of human enhancement. These technologies - including nanotechnology, neurotechnology, information technology, robotics and artificial intelligence - not only have unique capabilities, but have also instantiated separate ethical domains. This book discusses three possible human enhancement paradigms - the biomedical, the transhumanist and the social - and explores how each paradigm involves different values and different uses of technology. It also investigates the different degrees and kinds of ethical issues instantiated by each of these human enhancement paradigms. A framework to prioritise these human enhancement paradigms is advanced, a framework that promotes technological innovation that serves the improvement of the human condition in a respectful and sustainable way. More importantly, this is a framework that ensures that not only certain groups of individuals enjoy the benefits of technological innovation. Includes a foreword from Professor Steve Fuller, Auguste Comte Professor of Social Epistemology, University of Warwick, UK.
(source: Nielsen Book Data)9781137402233 20160618
SAL1&2 (on-campus shelving)
Book
xii, 249 p. : ill. ; 24 cm.
  • Methods in Trauma Biomechanics.- Head Injuries.- Spinal Injuries.- Thoracic Injuries.- Abdominal Injuries.- Injuries of the Pelvis and the Lower Extremities.- Injuries of the Upper Extremities.- Impairment and injuries resulting from chronic mechanical exposure.- Solutions to exercises.
  • (source: Nielsen Book Data)9783642037122 20160605
Trauma biomechanics uses the principles of mechanics to study the response and tolerance level of biological tissues under extreme loading conditions. Through an understanding of mechanical factors that influence the function and structure of human tissues, countermeasures can be developed to alleviate or even eliminate such injuries. Trauma Biomechanics surveys a wide variety of topics in injury biomechanics including injury classification, injury mechanisms and injury criteria. Both injuries sustained in automotive accidents and in sports are addressed. The interdisciplinary approach necessary in trauma biomechanics is stressed by showing the span from anatomy for each body region to engineering solutions for protection against injury. Injury tolerance values are listed, either currently in use or proposed by both the U.S. and European countries. Although the book is meant as a first introduction for engineers and medical doctors, sufficient references for scientific research are provided also. This third edition is revised and enlarged. In particular the unique introduction to Sport injuries is improved. In addition, many examples are included into the new edition.
(source: Nielsen Book Data)9783642037122 20160605
dx.doi.org SpringerLink
Book
xiii, 193 p. : ill., maps ; 24 cm.
  • 1. Exchange in human goods
  • 2. Making a gift
  • 3. The logistics of altruism
  • 4. Collection regimes and donor populations
  • 5. Organizations and obligations
  • 6. Managing gifts, making markets
  • App. Data and methods.
More than any other altruistic gesture, blood and organ donation exemplies the true spirit of self-sacrifice. Donors literally give of themselves for no reward so that the life of an individual - often anonymous - may be spared. But, as the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question, and the possibility has surfaced that donors might be supplemented or replaced by paid suppliers. "Last Best Gifts" offers a fresh perspective on this ethical dilemma, by examining the social organization of blood and organ donation in Europe and the United States. Gifts of blood and organs are not given everywhere in the same way or to the same extent - contrasts that allow Kieran Healy to uncover the crucial role that institutions play in creating the contexts for donations. Procurement organizations, he shows, sustain altruism by providing opportunities to give and by producing public accounts of what giving means. In the end, Healy suggests, successful systems rest on the fairness of the exchange, rather than the purity of a donor's altruism or the size of a financial incentive.
(source: Nielsen Book Data)9780226322377 20160528
Business Library
Book
xiii, 193 p. : ill., maps ; 24 cm.
More than any other altruistic gesture, blood and organ donation exemplies the true spirit of self-sacrifice. Donors literally give of themselves for no reward so that the life of an individual - often anonymous - may be spared. But, as the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question, and the possibility has surfaced that donors might be supplemented or replaced by paid suppliers. "Last Best Gifts" offers a fresh perspective on this ethical dilemma, by examining the social organization of blood and organ donation in Europe and the United States. Gifts of blood and organs are not given everywhere in the same way or to the same extent - contrasts that allow Kieran Healy to uncover the crucial role that institutions play in creating the contexts for donations. Procurement organizations, he shows, sustain altruism by providing opportunities to give and by producing public accounts of what giving means. In the end, Healy suggests, successful systems rest on the fairness of the exchange, rather than the purity of a donor's altruism or the size of a financial incentive.
(source: Nielsen Book Data)9780226322377 20160528
SAL1&2 (on-campus shelving)
Book
1 online resource : text file, PDF.
  • Experimental CNS Trauma: A General Overview of Neurotrauma Research-- Jonathan Lifshitz Combat TBI: History, Epidemiology and Injury Modes-- Ralph G. DePalma NEUROMECHANISMS IN BRAIN INJURY Development of Concepts in the Pathology of Traumatic Axonal and Traumatic Brain Injury-- William L. Maxwell Pathophysiology of Mild TBI: Implications for Altered Signaling Pathways-- Robert A. Laskowski, Jennifer A. Creed, and Ramesh Raghupathi Oxidative Stress, Brain-Edema, Blood-Brain Barrier Permeability and Autonomic Dysfunction from Traumatic Brain Injury-- Hale Zerrin Toklu and Nihal Tumer The Contributing Role of Lipid Peroxidation and Protein Oxidation in the Course of CNS Injury Neurodegeneration and Neuroprotection: An Overview-- Edward D. Hall IGF-1/IGF-R Signaling in Traumatic Brain Injury: Impact on Cell Survival, Neurogenesis, and Behavioral Outcome-- Sindhu K. Madathil and Kathryn E. Saatman Microglia in Experimental Brain Injury: Implications on Neuronal Injury and Circuit Remodeling-- Megan N. Evilsizor, Helen F. Ray-Jones, Timothy W. Ellis, Jr., Jonathan Lifshitz, and Jenna M. Ziebell Evaluating the Effects of APOE4 after Mild Traumatic Brain Injury in Experimental Models-- Rebekah Mannix and William P. Meehan III The Cytoprotective role of Prostaglandin D2 DP1 Receptor Against Neuronal Injury Following Acute Excitotoxicity and Cerebral Ischemia-- Sylvain Dore and Abdullah Shafique Ahmad MANAGEMENT IN CNS TRAUMA Chronic Pain in Neurotrauma: Implications on Spinal Cord and Traumatic Brain Injury-- Rabih A. Moshourab, Michael Schafer, and Elie D. Al-Chaer Nonconvulsive Seizures as Secondary Insults in Experimental Traumatic Brain Injury-- Laura Stone McGuire, Amade Bregy, Justin Sick, W. Dalton Dietrich, Helen M. Bramlett, and Thomas Sick Characterization and Management of Headache after Mild Traumatic Brain Injury-- Sylvia Lucas Traumatic Brain Injury (TBI)-Induced Spasticity: Neurobiology, Treatment, and Rehabilitation-- Prodip Bose, Jiamei Hou, and Floyd J. Thompson MODELING BRAIN INJURY Techniques and Methods of Animal Brain Surgery: Perfusion, Brain Removal, and Histological Techniques-- Jihane Soueid, Amaly Nokkari, and Joelle Makoukji Controlled Cortical Impact Model-- Nicole D. Osier, Jonathan R. Korpon, and C. Edward Dixon A Two-Model Approach to Investigate the Mechanisms Underlying Blast-Induced Traumatic Brain Injury-- Haoxing Chen, Shlomi Constantini, and Yun Chen Acute Pathophysiology of Blast Injury: From Biomechanics to Experiments and Computations: Implications on Head and Polytrauma-- Namas Chandra and Aravind Sundaramurthy Modeling Fluid Percussion Injury: Relevance to Human Traumatic Brain Injury-- Katharine Eakin, Rachel Rowe, and Jonathan Lifshitz IMAGING AND BIOMARKERS CNS Trauma Biomarkers and Surrogate Endpoints Pipeline from Bench to Bedside: A Translational Perspective-- Tarek H. Mouhieddine, Leeanna El Houjeiri, Mirna Sabra, Ronald Hayes, and Stefania Mondello The Use and Potential of pNF-H as a General Blood Biomarker of Axonal Loss: An Immediate Application for CNS Injury-- Gerry Shaw Exploring Serum Biomarkers for Mild Traumatic Brain Injury-- Linda Papa, Damyan Edwards, and Michelle Ramia Modeling the Neurobehavioral Consequences of Blast-Induced Traumatic Brain Injury Spectrum Disorder and Identifying Related Biomarkers-- Denes V. Agoston and Alaa Kamnaksh Magnetic Resonance Imaging Application in the Area of Mild and Acute Traumatic Brain Injury: Implication for Diagnostic Marker-- Arnold Toth Translational Metabolomics of Head Injury: Exploring Dysfunctional Cerebral Metabolism with ex Vivo NMR Spectroscopy-Based Metabolite Quantification-- Stephanie M. Wolahan, Daniel Hirt, and Thomas C. Glenn The Emerging Impact of microRNAs in Neurotrauma Pathophysiology and Therapy-- Oneil G. Bhalala Neuroproteome Dynamics in Modeled Brain Injury: A Systems Neurobiology Perspective-- Pavel Lizhnyak, Hiyab Yohannes, and Andrew K. Ottens Gene Interaction Hierarchy Analysis can be an Effective Tool for Managing Big Data Related to Unilateral Traumatic Brain Injury-- Todd E. White and Byron D. Ford Autoantibodies in CNS Trauma and Neuropsychiatric Disorders: A New Generation of Biomarkers-- Firas Kobeissy and Rabih A. Moshourab Systems Biology Application to Decipher Mechanisms and Novel Biomarkers in CNS Trauma-- Chenggang Yu and Firas Kobeissy NEUROCOGNITIVE AND NEUROBEHAVIORAL TOPICS IN BRAIN INJURY Neuropathology of Mild Traumatic Brain Injury: Correlation to Neurocognitive and Neurobehavioral Findings-- Erin D. Bigler Blast-Related Mild Traumatic Brain Injury: Neuropsychological Evaluation and Findings-- Nathaniel W. Nelson, Nicholas D. Davenport, and Scott R. Sponheim Persistent Cognitive Deficits: Implications of Altered Dopamine in Traumatic Brain Injury-- Hong Qu Yan, Nicole D. Osier, Jonathan Korpon, James W. Bales, Anthony E. Kline, Amy K. Wagner, and C. Edward Dixon NEUROREHABILITATION AND NEUROPROTECTION Rehabilitative Paradigms after Experimental Brain Injury: Relevance to Human Neurotrauma-- Corina O. Bondi, Roya Tehranian-DePasquale, Jeffrey P. Cheng, Christina M. Monaco, Grace S. Griesbach, and Anthony E. Kline Models of Posttraumatic Brain Injury Neurorehabilitation-- Michelle D. Failla and Amy K. Wagner Translational Considerations for Behavioral Impairment and Rehabilitation Strategies after Diffuse Traumatic Brain Injury-- Theresa Currier Thomas, Taylor A. Colburn, Kelsey Korp, Aida Khodadad, and Jonathan Lifshitz Endothelin, Cerebral Blood Flow, and Traumatic Brain Injury: Implications for a Future Therapeutic Target-- Justin C. Graves and Christian W. Kreipke, Application of Novel Therapeutic Agents for CNS Injury: NAAG Peptidase Inhibitors-- Bruce G. Lyeth Neuregulin-1 and Neurovascular Protection-- Limin Wu, Samantha J. Walas, Wendy Leung, Eng H. Lo, and Josephine Lok Potential Use of Calpain Inhibitors as Brain Injury Therapy-- Emilio B. Cagmat, Joy D. Guingab-Cagmat, A.V. Vakulenko, R.L. Hayes, and John Anagli Nanoparticles for Neurotherapeutic Drug Delivery in Neurodegenerative Disorders: Application in Neurotrauma-- Mark S. Kindy and Alexey Vertegel Stem Cell Therapy in Brain Trauma: Implications for Repair and Regeneration of Injured Brain in Experimental TBI Models-- Andrew Rolfe and Dong Sun Cortical Stimulation-Induced Structural Plasticity and Functional Recovery after Brain Damage-- DeAnna L. Adkins Cranial Nerve Noninvasive Neuromodulation: New Approach to Neurorehabilitation-- Yuri Danilov, Kurt Kaczmarek, Kimberly Skinner, and Mitchell Tyler MILD BRAIN INJURY AND SPORT CONCUSSION Blast Injuries and Blast-Induced Neurotrauma Overview of Pathophysiology and Experimental Knowledge: Models and Findings-- Ibolja Cernak Animal Models for Concussion: Molecular and Cognitive Assessments-Relevance to Sport and Military Concussions-- Hayde Bolouri and Henrik Zetterberg The Problem of Neurodegeneration in Cumulative Sports Concussions: Emphasis on Neurofibrillary Tangle Formation-- Vassilis E. Koliatsos and Leyan Xu SUBSTANCE ABUSE AND COMORBID CONDITIONS Evidence for Beneficial and Adverse Effects of Alcohol in Animal Models and Clinical Studies of Traumatic Brain Injury-- Anna N. Taylor and Richard L. Sutton Modeling TBI-Induced Alterations in Alcohol Use Behaviors-- James P. Caruso, Jennifer L. Lowing, and Alana C. Conti Index.
  • (source: Nielsen Book Data)9781466565982 20160618
Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. In addition, a section is devoted to models of mild CNS injury, including blast and sport-related injuries. This book, with its diverse coherent content, is a valuable and comprehensive reference for individuals interested in the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.
(source: Nielsen Book Data)9781466565982 20160618
Book
360 p. : ill.
  • Overview of Nutrition and Wound Healing, J. A. Molnar Carbohydrates and Wound Healing, C. Ireton-Jones and G. U. Liepa Fat and Wound Healing, J. J. Turek Protein and Wound Healing, M. L. Dylewski and Y.-M. Yu Glutamine and Wound Healing, M. B. Schoemann, C. D. Bechtold, S. Agrawal, and C. W. Lentz Arginine and Wound Healing, V. Ahuja, M. Rizk, and A. Barbul Water-Soluble B Vitamins and Wound Healing, G. U. Liepa, C. Ireton-Jones, H. Basu, and C. R. Baxter Vitamin C and Wound Healing, H. Tanaka and J. A. Molnar Fat-Soluble Vitamins and Wound Healing, M. M. Gottschlich Trace Elements and Wound Healing, T. G. Baumgartner Nutrition and Wound Healing in Burns, Trauma, and Sepsis, C. A. Watters, E. E. Tredget, and C. Cooper Nutrition and Wound Healing in Cancer, P. Shen and S. Martin Nutrition and Wound Healing at the Age Extremes, H. G. Piper, P. Javid, and T. Jaksic Pharmacological Manipulation of the Healing Wound: The Role of Hormones, R. H. Demling Index.
  • (source: Nielsen Book Data)9780849317316 20160528
With mounting evidence regarding the role of poor nutrition in the development of chronic diseases such as heart disease and diabetes, it is no secret that appropriate nutrition is crucial to optimal health. Achieving the correct balance of elements provides the body with the ability to adapt to a shifting and often hazardous environment. Never is this capability more important than when a wound is sustained and the body's first line of defense, the skin, is breached. "Nutrition and Wound Healing" describes the importance of several nutrients, both macronutrients and micronutrients, and their relation to the body's requirements when healing itself. Beginning with an overview to introduce the novice to the fundamentals of nutrition and wound healing, the text analyzes the role of each nutrient, chapter by chapter. The authors discuss carbohydrates, fats, proteins, trace elements, and fat- and water-soluble vitamins. Balanced attention is paid to conditions of deficiency as well as toxic excess as applicable to each nutrient. Specific challenges to healing are considered with individual chapters on burns, cancer, and age extremes. The book also includes a chapter on hormones and the pharmacologic manipulation of wound healing. Specific recommendations for the appropriate administration of each nutrient and variations for individual circumstances are discussed throughout the book. In addition, future directions of research are provided in each chapter to guide young investigators in the field. While many wounds heal well on their own, there are many circumstances when intervention is necessary. "Nutrition and Wound Healing" provides the clinician, researcher, and even the interested novice with the information he or she needs to know to help the body heal itself.
(source: Nielsen Book Data)9780849317316 20160528

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