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1 online resource (xxi, 1714 pages) : illustrations (chiefly color)
  • Section 1: History of the Therapy of Breast Cancer 1. History of the Therapy of Breast Cancer Section 2: Anatomy and Physiology of the Normal and Lactating Breast 2. Anatomy of the Breast, Axilla, Chest Wall, and Related Metastatic Sites 3. Breast Physiology: Normal and Abnormal Development and Function 4. Discharges and Secretions of the Nipple Section 3: Benign and Premalignant Lesions 5. Etiology and Management of Benign Breast Disease 6. Mastitis and Breast Abscess 7. Gynecomastia 8. Benign, High-Risk, and Premalignant Lesions of the Breast Section 4: Pathology of Malignant Lesions 9. In Situ Carcinomas of the Breast: Ductal Carcinoma in Situ and Lobular Carcinoma in Situ 10. Infiltrating Carcinomas of the Breast: Not One Disease 11. Mesenchymal Neoplasms and Primary Lymphomas of the Breast 12. Paget Disease of the Breast 13. Primary and Secondary Dermatologic Disorders of the Breast 14. Breast Biomarker Immunocytochemistry Section 5: Natural History, Epidemiology, Genetics, and Syndromes of Breast Cancer 15. Epidemiology of Breast Cancer 16. Primary Prevention of Breast Cancer 17. Breast Cancer Genetics: Syndromes, Genes, Pathology, Counseling, Testing, and Treatment Section 6: Prognostic Factors for Breast Cancer 18. Clinically Established Prognostic Factors in Breast Cancer 19. Molecular Prognostic Factors for Breast Carcinoma 20. Risk Factors for Breast Carcinoma in Women with Proliferative Breast Disease 21. Steroid Receptors in Breast Cancer Section 7: Molecular Biology of Breast Carcinogenesis 22. Molecular Oncology of Breast Cancer 23. Stem Cells in Breast Development and Cancer 24. Therapeutic Strategies for Breast Cancer Section 8: Screening and Diagnosis of Breast Disease 25. Examination Techniques: Roles of the Physician and Patient in Evaluating Breast Disease 26. Breast Imaging Screening and Diagnosis Section 9: Clinical Trials: Biostatistical Applications 27. Design and Conduct of Clinical Trials for Breast Cancer Section 10: Surgery for Benign and Malignant Diseases of the Breast 28. Indications and Techniques for Biopsy 29. General Principles of Mastectomy: Evaluation and Therapeutic Options 30. Halsted Radical Mastectomy 31. Modified Radical Mastectomy and Simple Mastectomy 32. Breast Conservation Therapy for Invasive Breast Cancer Section 11: Breast Reconstruction 33. Breast Reconstruction Techniques Section 12: Complications of Breast Surgery 34. Wound Care and Complications of Mastectomy 35. Quality Measures and Outcomes for Breast Cancer Surgery 36. Lymphedema in the Postmastectomy Patient: Pathophysiology, Prevention, and Management Section 13: Current Concepts and Management of Early Breast Carcinoma (Tis, Tmic, T1) 37. Assessment and Designation of Breast Cancer Stage 38. Biology and Management of Lobular Carcinoma in Situ of the Breast (Lobular Neoplasia) 39. Ductal Carcinoma in Situ 40. The New Paradigm: Oncoplastic Breast Conservation Surgery 41. Therapeutic Value of Axillary Node Dissection and Selective Management of the Axilla in Small Breast Cancers 42. Lymphatic Mapping and Sentinel Lymphadenectomy for Breast Cancer 43. Detection and Significance of Axillary Lymph Node Micrometastases 44. Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy 45. Surgical Management of Early Breast Cancer Section 14: Therapy for Stages 0, I, and II Breast Cancer 46. Biologic Basis of Radiotherapy of the Breast 47. Radiotherapy and Ductal Carcinoma in Situ 48. Radiotherapy and Regional Nodes 49. Postmastectomy Radiotherapy 50. Breast-Conserving Therapy for Invasive Breast Cancers 51. Partial Breast Irradiation: Accelerated and Intraoperative 52. Radiation Complications and Their Management 53. Radiation Therapy for Locally Advanced Breast Cancer: Historical Review to Current Approach 54. Adjuvant Endocrine Therapy 55. Adjuvant and Neoadjuvant Systemic Therapies for Early Stage Breast Cancer 56. Adjuvant HER2 Therapy 57. Bisphosphonates in Early Breast Cancer 58. Oncofertility Options for Young Women with Breast Cancer Section 15: Management of Advanced Local, Regional, and Systemic Disease 59. Surgical Procedures for Advanced Local and Regional Malignancies of the Breast 60. Solitary Metastases 61. Locoregional Recurrence after Mastectomy 62. Principles of Preoperative Therapy for Operable Breast Cancer 63. Locally Advanced Breast Cancer 64. Inflammatory Breast Cancer 65. Neoadjuvant Chemotherapy and Radiotherapy 66. Detection and Clinical Implications of Occult Systemic Micrometastatic Breast Cancer 67. Management of the Intact Breast Primary in the Setting of Metastatic Disease 68. Management of Bone Metastases in Breast Cancer 69. Chemotherapy and HER2-Directed Therapy for Metastatic Breast Cancer 70. Endocrine Therapy for Breast Cancer 71. Immunologic Approaches to Breast Cancer Therapy 72. Diagnosis and Management of Pleural Metastases in Breast Cancer 73. Management of Central Nervous System Metastases in Breast Cancer 74. Management of Pericardial Metastases in Breast Cancer Section 16: Special Presentations of Breast Cancer 75. Bilateral Breast Cancer 76. Cancer of the Male Breast 77. Local Recurrence, the Augmented Breast, and the Contralateral Breast 78. Carcinoma of the Breast in Pregnancy and Lactation 79. Unknown Primary Presenting with Axillary Lymphadenopathy 80. Clinical Management of the Patient at Increased or High Risk Section 17: Survivorship, Follow-Up Care, and Rehabilitation of the Breast Cancer Patient 81. General Considerations for Follow-Up 82. Management of Menopause in the Breast Cancer Patient 83. Rehabilitation 84. Psychosocial Consequences and Lifestyle Interventions 85. Survivorship with Breast Cancer Section 18: Medical and Legal Issues Specific to the Care of Breast Cancer 86. Delayed Diagnosis of Symptomatic Breast Cancer.
  • (source: Nielsen Book Data)9780323359559 20171017
Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast cancer detection and treatment in a practical, easy-to-use format ideal for today's surgeons.Delivers step-by-step clinical guidance highlighted by superb illustrations that depict relevant anatomy and pathology, as well as medical and surgical procedures. Reflects the collaborative nature of diagnosis and treatment among radiologists, pathologists, surgeons, oncologists, and other health care professionals who contribute to the management of patients with breast disease. Offers the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast. Covers the latest developments in receptor modulation, targeted monoclonal antibodies, evolving inhibitors with triple-negative disease, and more. Discusses recent minimally invasive surgical techniques and new developments in oncoplastic breast conservation techniques. Contains significant updates to the "Management of Systemic Disease" section that reflect the latest advances in chemotherapy, hormonal resistance, and therapy. Includes links to real-time procedure videos and full-color procedural line drawings from the Klimberg Atlas of Breast Surgical Techniques on Expert Consult, providing expert visual guidance on how to execute key steps and techniques. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.
(source: Nielsen Book Data)9780323359559 20171017
1 online resource : illustrations (chiefly color)
  • Section 1 Structural and Molecular Bases of Ion Channel Function 1. Voltage-Gated Sodium Channels and Electrical Excitability of the Heart 2. Voltage-Gated Calcium 3. Voltage-Gated Potassium Channels 4. Structural and Molecular Bases of Cardiac Inward Rectifier Potassium Channel Function 5. Mammalian Calcium Pumps in Health and Disease 6. Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function 7. Organellar Ion Channels and Transporters 8. Molecular Organization, Gating and Function of Connexin-based Gap Junction Channels and Hemichannels Section 2 Biophysics of Cardiac Ion Channel Function 9. Structure-function relations of Heterotrimetric complexes of sodium channel a and � subunits 10. Regulation of Cardiac Calcium Channels 11. Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome 12. Structural Determinants and Biophysical Properties of hERG1 Channel Gating 13. Molecular Regulation of Cardiac Inward Rectifier Potassium Channels by Pharmacological Agents 14. Cardiac Stretch-Activated Channels and Mechano-Electric Coupling 15. Biophysical Properties of Gap Junctions 16. Excitation-Contraction Coupling Section 3 Intermolecular Interactions and Cardiomyocyte Electrical Function 17. Ion Channel Trafficking in the Heart 18. Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5 19. Fibroblast growth factor homologous factors modulate cardiac calcium channels. 20. Macromolecular Complexes and Cardiac Potassium Channels 21. Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias 22. The intercalated disc: A molecular network that integrates electrical coupling, intercellular adhesion and cell excitability 23. Function and dysfunction of ion channel membrane trafficking and post translational modification 24. Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling. Section 4 Cell Biology of Cardiac Impulse Initiation and Propagation 25. Stem cell-derived nodal-like cardiomyocytes as a novel pharmacologic tool: insights from sinoatrial node development and function. 26. Gene Therapy and Biological Pacing 27. Intercellular Communication and Impulse Propagation 28. Mechanisms of normal and dysfunctional Sinoatrial Nodal Excitability and Propagation 29. Cell Biology of the Specialized Cardiac Conduction System 30. Cardiac Remodeling and Regeneration Section 5 Models of Cardiac Excitation 31. Ionic Mechanisms of Atrial Action Potentials 32. Genetic algorithms to generate dynamical complexity electrophysiological models 33. Calcium Signaling in Cardiomyocyte Models with Realistic Geometries 34. Theory of Rotors and Arrhythmias 35. Computational approaches for Accurate Rotor localization in the Human Atria 36. Modeling the aging heart Section 6 Neural Control of Cardiac Electrical Activity 37. Innervation of the sinoatrial node 38. Mechanism for altered autonomic and oxidant regulation of cardiac sodium currents. 39. Pulmonary Vein Ganglia and the Neural Regulation of the Heart Rate 40. Neural Activity and Atrial Tachyarrhythmias 41. Sympathetic Innervation and Cardiac Arrhythmias Section 7 Arrhythmia Mechanisms 42. The Molecular Pathophysiology of Atrial Fibrillation 43. Myofibroblasts, Cytokines, and Persistent Atrial Fibrillation 44. Role of the Autonomic Nervous System in Atrial Fibrillation 45. Rotors in Human Atrial Fibrillation 46. Body surface frequency-phase mapping of atrial fibrillation. 47. Panoramic Mapping of Atrial Fibrillation from the body surface 48. Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation 49. Genetics of Atrial Fibrillation Section 8 Molecular Genetics and Pharmacogenomics 50. Mechanisms in Heritable Sodium Channel Diseases 51. Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes 52. Inheritable Potassium Channel Diseases 53. Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation Section 9 Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction 54. Pharmacologic Bases of Antiarrhythmic Therapy 55. Pharmacogenomics of Cardiac Arrhythmias 56. Gene therapy to treat cardiac arrhythmias 57. Highly Mature Human iPSC-Derived Cardiomyocytes as Models for Cardiac Electrophysiology and Drug Testing 58. Cardiac repair with human induced pluripotent stem cell-derived cardiovascular cells. Section 10 DIAGNOSTIC EVALUATION 59. Assessment of the patient with a cardiac arrhythmia 60. Electrocardiography of tachyarrhythmias: Differential diagnosis of narrow and wide QRS complex tachycardias 61. Electroanatomic Mapping for arrhythmias 62. Computed tomography for electrophysiology 63. Magnetic resonance imaging for electrophysiology 64. Intracardiac echocardiography for electrophysiology 65. Exercise-induced arrhythmias 66. Cardiac monitoring: short- and long-term recording 67. Head-up Tilt Table Testing 68. Autonomic Regulation and Cardiac Risk 69. T-wave alternans 70. Noninvasive Electrocardiographic Imaging of Human Ventricular Arrhythmias and Electrophysiological Substrate 71. Genetic testing Section 11 SUPRAVENTRICULAR TACHYARRHYTHIAS: MECHANISMS, CLINICAL FEATURES, AND MANAGEMENT 72. Sinus node abnormalities 73. Atrial tachycardia 74. Atrial tachycardia in adults with congenital heart disease 75. Typical and Atypical Atrial Flutter: Mapping and Ablation 76. Atrial fibrillation 77. Preexcitation, Atrioventricular reentry, Variants 78. Electrophysiological Characteristics of Atrioventricular Nodal Reentrant Tachycardia: Implications for the Rentrant Circuits 79. Junctional tachycardia Section 12 VENTRICULAR TACHYCARRHYTHMIAS: MECHANISMS, CLNICAL FEATURES, AND MANAGEMENT 80. Premature ventricular complexes 81. Outflow tract ventricular tachycardias: Mechanisms, Clinical Features, and Management 82. Fascicular ventricular arrhythmias 83. Bundle branch reentry tachycardia 84. Ischemic heart disease 85. Ventricular Tachycardia in Patients with Dilated Cardiomyopathy 86. Ventricular Arrhythmias in Hypertrophic Cardiomyopathy 87. Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy 88. VTs in Catcholaminergic Cardiomyopathy (Catecholaminergic polymorphic ventricular tachycardia) 89. Ventricular Arrhythmias in Heart failure 90. Arrhythmias and conduction disturbances in Non Compaction Cardiomyopathy 91. Takotsubo cardiomyopathy 92. Brugada syndrome 93. Long and short QT syndromes 94. Anderson-Tawil syndrome 95. Timothy syndrome 96. J Wave Syndromes 97. Idiopathic ventricular fibrillation 98. Sudden infant death syndrome 99. Sudden cardiac arrest/death in adults 100. Neurologic disorders 101. Drug-Induced Ventricular Tachycardia 102. Ventricular Arrhythmias in Congenital Heart Disease Section 13 SYNCOPE and Bradyarrhythmias 103. Syncope 104. Postural orthostatic tachycardia syndrome 105. Progressive conduction system disease 106. Atrioventricular block Section 14 ARRHYTHMIAS IN SPECIAL POPULATIONS PHARMACOLOGIC THERAPY 107. Sex differences in arrhythmias 108. Sudden cardiac death in athletes, inlcuding commotio cordis 109. Pediatric populations 110. Sleep-disordered breathing and arrhythmias 111. Ventricular Assist devices and Cardiac Transplantation Recipients Section 15 PHARMACOLOGIC THERAPY 112. Standard antiarrhythmic drugs 113. Innovations In Antiarrhythmic Drug Therapy 114. Nontraditional drugs for sudden cardiac death 115. Prevention of stroke in atrial fibrillation: warfarin, anti-factor Xa and thrombin drugs Section 16 CARDIAC IMPLANTABLE ELECTRONIC DEVICES 116. Implantable cardioverter defibrillators: technical aspects 117. Implantable cardioverter defibrillators: clinical aspects 118. Subcutaneous implantable defibrillator 119. Implantable pacemakers 120. Cardiac resynchronization therapy 121. Newer applications of pacemakers 122. Remote monitoring Section 17 CATHETER ABLATION 123. Catheter Ablation: Technical aspects 124. Catheter Ablation: Clinical aspects 125. Ablation for Atrial fibrillation 126. Ablation of Supraventricular tachycardias 127. Catheter Abliation for Ventricular tachycardias with/without structural heart disease 128. Epicardial and other approaches 129. Ventricular fibrillation 130. Ablation in Pediatrics 131. Congenital heart disease 132. Anesthesiology for EP procedures Section 18: SURGERY FOR ARRHYTHMIAS 133. Surgery for Atrial fibrillation and other supraventricular tachycardias 134. Surgery for Ventricular tachycardia Section 19 NEW APPROACHES 135. Cervical vagal stimulation for heart failure 136. Baroreflex stimulation 137. Spinal cord stimulation for heart failure and Arrhythmias 138. Renal artery denervation 139. Left atrial appendage occlusion/ligation.
  • (source: Nielsen Book Data)9780323447331 20170814
Rapid advancements in cardiac electrophysiology require today's health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field.
(source: Nielsen Book Data)9780323447331 20170814
1 online resource (356 p.) : ill. (some col.).
"Cardioprotective Natural Products: Promises and Hopes focuses on the recent advances in the research of bioactive natural products with cardioprotective potential against various cardiovascular diseases/disorders. The aim of this book is to underline the promise and future hope in bioactive natural molecules, herbal formulations, natural dietary supplements and related materials in the prevention and cure of cardiovascular diseases in a scientific way. This book, which comprises a variety of about 9 chapters written by active researchers and leading experts, brings together an overview of current discoveries and trends in this field. This volume is also an outstanding source of information with regard to the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach adopted in this book ensures that it is much more interesting to scientists deeply engaged in the research and/or use of bioactive natural products. It will serve not only as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to prevent and treat disease manifestations, but will hopefully also motivate young scientists to engage in the dynamic field of natural products research."--Publisher's website.
1 online resource
Keeping up with the use of new technologies in cardiology is becoming increasingly challenging. Case Studies in Clinical Cardiac Electrophysiology helps to bridge the gap between knowledge and application with 28 cases spanning both common and uncommon arrhythmias and ablation scenarios, each of which includes the clinical presentation, baseline ECG, ECG during arrhythmia, stepwise electrophysiologic diagnostic maneuvers and some of their pitfalls, and optimal therapy. Online access to the complete contents ensures the information you need is right at your fingertips.
1 online resource (xix, 463 pages) : color illustrations.
1 online resource (xxii, 487 pages) : illustrations (some color)
  • Epidemiology of chronic coronary artery disease
  • The global perspective of ischemic heart disease
  • Genetics of coronary atherosclerosis
  • Basic mechanisms of atherosclerosis
  • Coronary microvascular dysfunction
  • Precipitants of myocardial ischemia
  • History and physical examination
  • Lipid measurements
  • Standard and novel biomarkers
  • ECG and standard exercise stress testing
  • Echocardiography
  • Nuclear imaging and pet
  • CT and MRI
  • Invasive testing
  • Putting it all together : which test for which patient?
  • Goals of therapy
  • Global risk assessment
  • Lifestyle interventions
  • Obesity and the obesity paradox
  • The medical treatment of stable angina
  • Antiplatelet and anticoagulant drugs
  • Prevention of sudden cardiac death
  • Revascularization approaches
  • Managing chronic coronary artery disease in patients with diabetes
  • Angina in patients with evidence of myocardial ischemia and no obstructive coronary artery disease
  • Depression, anxiety, and stress
  • Refractory angina
  • Primary prevention of atherosclerotic cardiovascular disease
  • Screening for atherosclerotic cardiovascular disease in asymptomatic individuals
  • Secondary prevention of coronary artery disease.
Featuring expert guidance from Drs. James de Lemos and Torbjorn Omland, as well as other globally known leaders in cardiology, Chronic Coronary Artery Disease covers every aspect of managing and treating patients suffering from chronic coronary syndromes. This brand-new companion to Braunwald's Heart Disease was designed as a stand-alone reference for physicians treating patients who present with complex, unique challenges, offering the latest information on the use of imaging modalities in diagnosis and treatment, advances in interventional and surgical approaches to revascularization, new medications to improve symptoms and outcomes in chronic CAD, and much more. Relevant updates to the text are sourced regularly from the parent reference, Braunwald's Heart Disease and delivered on Expert Consult at no additional cost. These updates cover late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald.
1 online resource. Digital: text file; PDF.
  • Chapter 1. Introduction and Biogeography (Jessica Halofsky, David Peterson, and Karen Dante-Wood).- Chapter 2. Climatology (Linda Joyce and Marian Talbert).- Chapter 3. Water Resources (Chales Luce).- Chapter 4. Fisheries (Michael Young and Daniel Isaak). - Chapter 5. Forest Vegetation (Robert Keane).- Chapter 6.- Non-Forest Vegetation (Matthew Reeves).- Chapter 7. Ecological Disturbance (Rachel Loehman).- Chapter 8. - Wildlife (Kevin McKelvey and Polly Buotte).- Chapter 9. Recreation (Michael Hand and Megan Lawson).- Chapter 10.- Ecosystem Services (Travis Warziniack).- Chapter 11. Cultural Resources (Carl Davis).- Chapter 12. Applications in Resource Management and Planning (Karen Dante-Wood and Linh Hoang).
  • (source: Nielsen Book Data)9783319569277 20171127
This book is the result of a team of approximately 100 scientists and resource managers who worked together for two years to understand the effects of climatic variability and change on water resources, fisheries, forest vegetation, non-forest vegetation, wildlife, recreation, cultural resources and ecosystem services. Adaptation options, both strategic and tactical, were developed for each resource area. This information is now being applied in the northern rocky Mountains to ensure long-term sustainability in resource conditions.The volume chapters provide a technical assessment of the effects of climatic variability and change on natural and cultural resources, based on best available science, including new analyses obtained through modeling and synthesis of existing data. Each chapter also contains a summary of adaptation strategies (general) and tactics (on-the-ground actions) that have been developed by science-management teams.
(source: Nielsen Book Data)9783319569277 20171127
1 online resource (xi, 631 pages) : illustrations (chiefly color)
  • Preinvasive disease of the cervix / L. Stewart Massad
  • Preinvasive disease of the vagina and vulva and related disorders / Cara A. Mathews and Joan L. Walker
  • Invasive cervical cancer / Krishnansu S. Tewari and Bradley J. Monk
  • Endometrial hyperplasia, estrogen therapy, and the prevention of endometrial cancer / Lisa M. Landrum, Rosemary E. Zuna, and Joan L. Walker
  • Adenocarcinoma of the uterine corpus / William T. Creasman and David Scott Miller
  • Sarcoma of the uterus / D. Scott McMeekin and William T. Creasman
  • Gestational trophoblastic disease / Emma L. Barber and John T. Soper
  • Invasive cancer of the vulva / Thomas Herzog
  • Invasive cancer of the vagina / Marilyn Huang, Brian M. Slomovitz, and Robert L. Coleman
  • The adnexal mass / Camille C. Gunderson, Robert S. Mannel, and Philip J. Di Saia
  • Epithelial ovarian cancer / Eric L. Eisenhauer, Ritu Salani, and Larry J. Copeland
  • Germ cell, stromal, and other ovarian tumors / Emily R. Penick, Chad Hamilton, G. Larry Maxwell, and Charlotte S. Marcus
  • Fallopian tube cancer / Erica R. Hope, G. Larry Maxwell, and Chad A. Hamilton
  • Breast diseases / Patricia A. Cronin and Mary L. Gemignani
  • Cancer in pregnancy / Krishnansu S. Tewari
  • Complications of disease and therapy / Kemi M. Doll, Daniel L. Clarke-Pearson
  • Basic principles of chemotherapy / Christina S. Chu and Stephen C. Rubin
  • Targeted therapy and molecular genetics / Shannon N. Westin, Anil K. Sood, and Robert L. Coleman
  • Genes and cancer : genetic counseling and clinical management / David G. Mutch, Sheri Babb, and Philip J. Di Saia
  • Palliative care and quality of life / Dana M Chase, Siu-Fun Wong, Lari Wenzel, and Bradley J. Monk
  • Role of minimally invasive surgery in gynecologic malignancies / Floor J. Backes, David E. Cohn, Robert S. Mannel, and Jeffrey M. Fowler
  • Epidemiology of commonly used statistical terms and analysis of clinical studies / Wendy R. Brewster
  • Basic principles in gynecologic radiotherapy / Catheryn M. Yashar
  • Appendices. Staging: staging of cancer at gynecologic sites
  • Modified from common terminology criteria for adverse events (common terminology criteria for adverse events)
  • Blood component therapy
  • Suggested recommendations for routine cancer screening
  • Nutritional therapy.
The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers - a must-have reference for improving outcomes and providing effective care. A "who's who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference.
(source: Nielsen Book Data)9780323400671 20170410
1 online resource.
  • Chapter 1: Pathophysiology of atherosclerosis Biology of the vessel wall Endothelial function Atherosclerotic plaque Risk factors (dyslipidemia, smoking, hypertension etc.) The role of inflammation The role of oxidative stress Genetics of atherosclerosis Chapter 2: Coronary artery circulation: Basic principles Functional anatomy Myocardial oxygen consumption Regulation of oxygen transport and coronary blood flow Stable angina pectoris Acute coronary syndromes Chapter 3: Novel and experimental therapies in advance atherosclerosis Anti-inflammatory treatments Anti-oxidant treatment Gene-therapy Stem-cell therapy Diagnostic strategies-novel imaging modalities-multimodalities and hybrid techniques Novel antiplatelet agents Primary percutaneous coronary intervention Novel developments in interventional strategies.
  • (source: Nielsen Book Data)9780128119082 20171204
Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management round out this comprehensive tome that is ideal for practitioners and researchers. By summarizing this novel knowledge and changes in diagnostic algorithm and treatment options, this is the perfect reference for cardiology researchers who want a volume with the most up-to-date experimental trends in the field of atherosclerosis, for cardiologists and physicians who manage patients with atherosclerotic risk factors and established coronary artery disease, and medical students who want to learn the basic concepts of atherosclerosis.
(source: Nielsen Book Data)9780128119082 20171204
xvii, 135 pages ; 23 cm.
  • Foreword Dr Richard Greenwood, Series foreword Barbara A Wilson, Acknowledgments, Preface, The start of the (almost) end, The most exciting day of my life, My boring history, The Wellington hospital, A second childhood, The wheelchair and me, Standing on two feet, Understanding and feeling, The Bleakness, Clothes make the man, A birthday in hospital, A tilted point of view, The assault on self , End of an era, The national health service, The death of ambition, Other peoples' stories, The Oliver Zangwill Centre, The idealism of youth, The land of OZ, Perfectionism, The rainbow, The importance of semantics, The traumatic brain injury fraternity, A return to the institution, Writing, Excuses and choices, A constructive pastime, An (almost) new start, Epilogue, A little bit about the author, Index, References, Further reading.
  • (source: Nielsen Book Data)9781138055650 20171017
Whilst preparing for his travel adventures into a world he had yet to explore, Christopher Yeoh was involved in a road traffic accident and experienced something few others would be "privileged" to witness. Eight days in a coma, more than a year in and out of hospital and a gradual re-introduction to the world of work. A Different Perspective After Brain Injury: A Tilted Point of View is written entirely by the survivor, providing an unusually introspective and critical personal account of life following a serious blow to the head. It charts the initial insult, early rehabilitation, development of understanding, the return of emotion, moments of triumph and regression into depression, the exercise of reframing how a brain injury is perceived and a return to work. It also describes the mental adjustments of awareness and acceptance alongside the physical recovery process. Readily accessible to the general public, this book will also be of particular interest to professionals involved in the care of people who have had significant brain injuries, brain injury survivors, their families and friends and also those who fund and organise health and social care. This unique author account will provide a degree of understanding of what living with a hidden disability is really like.
(source: Nielsen Book Data)9781138055650 20171017
Green Library
1 electronic resource.
  • Chapter 1. Epidemiology of drug allergy
  • Chapter 2. Economic impact of drug allergy
  • Chapter 3. Drug allergy: definitions and phenotypes
  • Chapter 4. Immune mechanisms of drug allergy
  • Chapter 5. Pharmacogenomics of drug allergy
  • Chapter 6. Cutaneous reactions to drugs
  • Chapter 7. Basics of skin testing and drug challenges
  • Chapter 8. In vitro and in vivo tests for drug hypersensitivity reactions
  • Chapter 9. Drug desensitization
  • Chapter 10. Penicillins
  • Chapter 11. Cephalsporin allergy
  • Chapter 12. Macrolide allergy
  • Chapter 13. Quinolone allergy
  • Chapter 14. Sulfonamide drug allergy
  • Chapter 15. Other antibiotic allergy
  • Chapter 16. Multiple drug intolerance syndrome
  • Chapter 17. Aspirin-exacerbated respiratory disease
  • Chapter 18. Other NSAIDs reactions
  • Chapter 19. Chemotherapy allergy
  • Chapter 20. Hypersensitivity reactions to monoclonal antibodies
  • Chapter 21. Perioperative allergy
  • Chapter 22. Adverse reactions to contrast media
  • Chapter 23. Corticosteroids
  • Index.
1 online resource.
  • Section 1 - Endoscoping liver patients: safety issues 1. Equipment, sterilisation and training issues 2. Sedation and analgesia in liver disease 3. Endoscopy and coagulation abnormalities in the liver patient 4. Patients with specific aetiologies (viral, bariatric, nafld, vcjd, alcohol) Section 2 - Endoscopic management of portal hypertension 4. Diagnosis and staging of oesophagogastric varices 5. Endoscopic management of acute variceal bleeding 6. Primary and secondary variceal prophylaxis: role of endoscopy 7. Refractory variceal bleed: when endoscopy fails what next?: 8. Gastropathy and gastric vascular ectasias in portal hypertension 9. Portal hypertensive enteropathy and colopathy 10. Endoscopic ultrasound in the diagnosis and management of portal hypertension 11. Wireless capsule endoscopy in liver disease Section 3 - Endoscopic diagnosis and management of gastrointestinal pathology in the liver patient 12. Common gastrointestinal pathology in the liver patient (barrett s, pud, gastropathy, celiac, polypoid lesions) 13. Anaemia and obscure gi bleed in the liver patient 14. ERCP and cholangioscopy in hepatobiliary disease 15. EUS in the diagnosis of hepatobiliary malignancy 16. Endomicroscopy in the diagnosis of hepatobiliary disease 17. Laparoscopy in patients with hepatobiliary disease Section 4 - Endoscopy in the liver transplant patient 18. Endoscopy of the liver patient prior to liver transplantation 19. Endoscopy of the post- liver transplant patient 20.luminal diseases in the liver transplant patient.
  • (source: Nielsen Book Data)9781118660799 20171121
Liver disease is an increasingly common cause of mortality, and its management is often complex and challenging. Endoscopy has in recent times undergone a period of rapid progress, with numerous novel and specialized endoscopic modalities that are of increasing value in the investigation and management of the patient with liver disease. As the technology in endoscopy expands, both as a diagnostic and interventional procedure, so does the role of the endoscopist in liver disease. This full colour book and companion website offer a comprehensive guidance as to when, why, and how to perform endoscopy to best manage your patients. Brings together two key areas liver disease and endoscopy into one expert clinical textbookCovers the entire spectrum of clinical problems that gastroenterologists and endoscopists face while managing patients with liver diseaseIncludes the latest management guidelines from the key international societies, such as the ASGE, AASLD, EASL and BSGWell illustrated with over 150 high-quality colour images11 high-quality videos illustrating optimum endoscopy practice, all clearly referenced in the text An indispensable tool for all gastroenterologists, hepatologists and endoscopists, Endoscopy in Liver Disease is perfect for learning how to perform endoscopy safely and effectively in the patient population with liver disorders.
(source: Nielsen Book Data)9781118660799 20171121
21 PDFs (xxxvii, 349 pages) : illustrations
  • Chapter 1. Medical students' quest towards the long white coat: impact on mental health and well-being
  • Chapter 2. Medical students' perceived stigma in seeking care: a cultural perspective
  • Chapter 3. Perfectionism: addressing lofty expectations in medical school
  • Chapter 4. Medical student burnout: a social cognitive learning perspective on medical student mental health and wellness
  • Chapter 5. Deliberate self-harm and suicide ideology in medical students
  • Chapter 6. From medical student to medical resident: graduate medical education and mental health in the United States
  • Chapter 7. Resident physician and medical academic faculty burnout: a review of current literature
  • Chapter 8. Developing a comprehensive wellness program for medical students
  • Chapter 9. Medical school wellness initiatives
  • Chapter 10. Essentials for education and training for tomorrow's physicians.
Discussions surrounding mental health are becoming more prominent and these conditions are becoming less stigmatized. Studying the effects that mental wellness has on students within the medical field can provide an insider perspective on this critical topic. Exploring the Pressures of Medical Education From a Mental Health and Wellness Perspective is a critical reference source that examines the mental and emotional problems that arise with students practicing in the medical field. Featuring relevant topics such as student burnout, cognitive learning, graduate education, and curriculum development, this scholarly publication is ideal for medical practitioners, academicians, students, and researchers that are interested in staying apprised of the latest trends and developments relating to mental wellness.
(source: Nielsen Book Data)9781522528128 20171211
1 online resource.
  • The cardiac electrical system
  • Abnormal heart rhythms
  • Treatment of arrhythmias
  • The electrophysiology study in the evaluation and therapy of cardiac arrhythmias
  • Principles of the electrophysiology study
  • The electrophysiology study in the evaluation of bradycardia : the SA node AV node and his purkinje system
  • The electrophysiology study in the evaluation of supraventricular tachyarrhythmias
  • The electrophysiology study in the evaluation and treatment of ventricular arrhythmias
  • Transcatheter ablation : therapeutic electrophysiology
  • Ablation of supraventricular tachycardias
  • Ablation of PVCS and ventricular tachycardia
  • Ablation of atrial fibrillation
  • Ablation of atrial flutter
  • Cardiac resynchronization : pacing therapy for heart failure
  • The evaluation of syncope
  • Electrophysiologic testing in perspective : the evaluation and treatment of cardiac arrhythmias.
1 online resource (ix, 260, e98 pages) : illustrations (some color)
  • PART ONE: Basic Principles and Patterns * Essential Concepts: What is an ECG? * ECG Basics: Waves, Intervals, and Segments * How to Make Basic Measurements * ECG Leads * The Normal ECG * Electrical Axis and Axis Deviation * Atrial and Ventricular Enlargement * Ventricular Conduction Disturbances: Bundle Branch Blocks and Related Abnormalities * Myocardial Infarction and Ischemia, Part I: ST Segment Elevation and Q Wave Syndromes * Myocardial Infarction and Ischemia, Part II: Non-ST Segment Elevation and Non-Q Wave Syndromes * Drug Effects, Electrolyte Abnormalities, and Metabolic Effects * Pericardial, Myocardial, and Pulmonary Syndromes PART TWO: Cardiac Rhythm Disturbances 13. Sinus and Escape Rhythms 14. Supraventricular Arrhythmias, Part I: Premature Beats and Paroxysmal Supraventricular Tachycardias (PSVTs) 15. Supraventricular Arrhythmias, Part II: Atrial Flutter and Atrial Fibrillation 16. Ventricular Arrhythmias 17. AV Conduction Abnormalities, Part I: Delays, Blocks, and Dissociation Syndromes 18. AV Conduction Abnormalities, Part II: Preexcitation (Wolff-Parkinson-White) Patterns and Syndromes PART THREE: Special Topics and Reviews 19. Bradycardias and Tachycardias: Review and Differential Diagnosis 20. Digitalis Toxicity 21. Sudden Cardiac Arrest and Sudden Cardiac Death 22. Pacemakers and Implantable Cardioverter-Defibrillators: Essentials for Clinicians 23. Interpreting ECGs: An Integrative Approach 24. Limitations and Uses of the ECG 25. ECG Differential Diagnoses: Instant Replays.
  • (source: Nielsen Book Data)9780323401692 20170612
Ideal for students and as a review for practicing clinicians, Goldberger's Clinical Electrocardiography explains the fundamentals of ECG interpretation and analysis, helping facilitate an understanding of rhythm disorders and the relevant clinical outcomes. The authors take readers through the nuts and bolts of ECG, using Dr. Ary Goldberger's award-winning teaching style to clarify complex concepts in an easy-to-read manner. You'll learn simple waveform analysis and beyond to present ECGs as they are used in hospital wards, outpatient clinics, emergency departments, and most especially intensive care units - where the recognition of normal and abnormal patterns is the starting point in patient care.
(source: Nielsen Book Data)9780323401692 20170612
1 online resource.
  • Heart Failure Epidemiology Chapter 1 Introduction Chapter 2 Pathophysiology and Risk Profiles of Heart Failure Chapter 3 Research and Design Chapter 4 Biostatistical Basis of Inference in Heart Failure Study Chapter�5 Advanced Biostatistics and Epidemiology Applied in Heart Failure Study Chapter 6 Precision Medicine and Areas for Further Research INDEX.
  • (source: Nielsen Book Data)9780323485586 20171204
Get a quick, expert overview of the many key facets of heart failure research with this concise, practical resource by Dr. Longjian Liu. This easy-to-read reference focuses on the incidence, distribution, and possible control of this significant clinical and public health problem which is often associated with higher mortality and morbidity, as well as increased healthcare expenditures. This practical resource brings you up to date with what's new in the field and how it can benefit your patients.Features a wealth of information on epidemiology and research methods related to heart failure. Discusses pathophysiology and risk profile of heart failure, research and design, biostatistical basis of inference in heart failure study, advanced biostatistics and epidemiology applied in heart failure study, and precision medicine and areas of future research. Consolidates today's available information and guidance in this timely area into one convenient resource.
(source: Nielsen Book Data)9780323485586 20171204
1 online resource (xvi, 425 pages) : illustrations (some color).
1 online resource.
"Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1.Features coverage on the prevention of, or inhibition of, liver fibrosis, cirrhosis, and hepatocellular carcinomaPresents data from trials on patients with diverse ethnic backgrounds and those infected with genotypes 3, 4, 5, 6Addresses the epidemiology, modes of transmission, socio-political aspects, genotypes, and co-infections of Hepatitis C"-- Provided by publisher.
1 online resource : illustrations (chiefly color)
  • SECTION I: EPIDEMIOLOGY 1. General Population and Global Cardiovascular Risk Prediction 2. Hypertension in Latin/Hispanic Population 3. Hypertension in East Asians and Native Hawaiians 4. Hypertension in South Asians SECTION II: PATHOPHYSIOLOGY 5. Pathogenesis of Hypertension 6. Genetics of Hypertension 7. Inflammation and Immunity in Hypertension SECTION III: DIAGNOSIS AND EVALUATION 8. The Environment and High Blood Pressure 9. Office Blood Pressure Measurement 10. Home Monitoring of Blood Pressure 11. Ambulatory Blood Pressure Monitoring in Clinical Hypertension Management 12. White Coat and Masked Hypertension 13. Renovascular Hypertension and Ischemic Nephropathy 14. Secondary Hypertension: Primary Hyperaldosteronism and Mineralocorticoid Excess States 15. Secondary Hypertension: Pheochromocytoma and Paraganglioma 16. Secondary Hypertension: Sleep Disturbances including Sleep Apnea 17. Hypertension in Children: Diagnosis and Treatment SECTION IV: RISK STRATIFICATION 18. Natural History of Untreated Hypertension 19. Isolated Systolic Hypertension 20. Assessment of Target Organ Damage SECTION V: ANTIHYPERTENSIVE THERAPY 21. Diet and Blood Pressure 22. Diuretics in Hypertension 23. Alpha Blockers and Hypertension 24. Renin Angiotensin Aldosterone System Blockers 25. Calcium Channel Blockers 26. Central Sympathetic Agents and Direct Vasodilators 27. Use of Combination Therapies 28. Devices Therapies 29. Alternative Approaches for Lowering Blood Pressure SECTION VI: HYPERTENSION MANAGEMENT 30. Approach to Difficult to Manage Primary Hypertension 31. Hypertension in Ischemic Heart Disease 32. Heart Failure 33. Hypertension and Chronic Kidney Disease 34. Transplant Hypertension 35. Obesity 36. Cerebrovascular Disease 37. Diabetes Mellitus 38. Dyslipidemia SECTION VII: SPECIAL POPULATIONS AND SPECIAL SITUATIONS 39. Hypertension in Pregnancy 40. Hypertension in Older People 41. Hypertension in African Americans 42. Baroreceptor Dysfunction/Orthostatic Hypotension 43. Resistant Hypertension 44. Hypertension and the Perioperative Period 45. Aorta and Peripheral Arterial Disease in Hypertension 46. Hypertensive Emergencies and Urgencies SECTION VIII: OUTCOME TRIALS 47. Meta-Analyses of Blood Pressure Lowering Trials and the Blood Pressure Lowering Treatment Trialists' Collaboration SECTION IX: HYPERTENSION TREATMENT IN THE FUTURE 48. Team-Based Care for Hypertension Management 49. Understanding and Improving Medication Adherence SECTION X: GUIDELINES 50. Updated AHA/ACC-- ESH/ISH 51. Putting All Guidelines into Perspective.
  • (source: Nielsen Book Data)9780323429733 20170410
The third edition of Hypertension: A Companion to Braunwald's Heart Disease, by Drs. George L. Bakris and Matthew Sorrentino, focuses on every aspect of managing and treating patients who suffer from hypertensive disorders. Designed for cardiologists, endocrinologists and nephrologists alike, this expansive, in-depth review boasts expert guidance from contributors worldwide, keeping you abreast of the latest developments from basic science to clinical trials and guidelines. Hypertension also includes an Expert Consult eBook updated with late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald.
(source: Nielsen Book Data)9780323429733 20170410
1 online resource (xiii, 658 pages) : illustrations (some color), color map
  • Section 1: Lung Cancer Control and Epidemiology 1. Classical Epidemiology 2. Tobacco Control and Primary Prevention 3. Tobacco Cessation 4. Non-Smoking Related Lung Cancer 5. Gender-Related Differences in Lung Cancer 6. Genetic Susceptibility to Lung Cancer 7. Early Detection and Radiologic Screening 8. Preclinical Biomarkers for The Early Detection of Lung Cancer 9. Chemoprevention of Lung Cancer: Present and Developing Technologies Section 2: Lung Cancer Molecular Carcinogenesis 10. Copy Number Abnormalities and Gene Rearrangements in Lung Cancer: Present and Developing Technologies 11. Mutational Events in Lung Cancer: Present and Developing Technologies 12. Epigenetic Events, Alterations, and Remodeling in Lung Cancer: Present and Developing Technologies 13. Stem Cells and Lung Cancer: In Vitro and In Vivo Studies 14. Microenvironment and Lung Cancer 15. MicroRNAs as Biomarkers for Lung Cancer Section 3: Immunology 16. Humoral and Cellular Immune Dysregulation and Lung Cancer Section 4: Pathology 17. Classic Anatomic Pathology and Lung Cancer 18. Molecular Testing and Lung Cancer 19. Management of the Small Biopsy in the Molecular Er Section 5: Clinical and Radiologic Presentation of Lung Cancer 20. Clinical Presentation 21. Conventional Imaging Lung Cancer 22. PET Imaging of Lung Cancer Section 6: Diagnosis and Staging of Lung Cancer 23. Diagnostic Work-Up of Suspected Lung Cancer 24. Surgical Staging of the Mediastinum including Mediastinoscopy and Thoracoscopy, Preoperative and Intraoperative 25. The 8th Edition of the Tumor, Node and Metastasis Classification of Lung Cancer Section 7: Surgical Management of Lung Cancer 26. Preoperative Functional Evaluation of the Surgical Candidate 27. Results of Video Assisted Techniques for Resection of Lung Cancer 28. Results of Robotic Techniques for Resection of Lung Cancer 29. Extent of Surgical Resection for Stage I and II Lung Cancer 30. Extended Resections for Lung Cancer: Chest Wall and Pancoast Tumors 31. Extended Resections for Lung Cancer: Broncho/Vascular Sleeve Resections 32. Multiple Nodules: Management of the Patient with Synchronous or Metachronous Lung Cancers 33. Surgical Management of the Marginally Resectable Patient Section 8: Radiotherapeutic Management of Lung Cancer 34. Technical Requirements for Lung Cancer Radiotherapy 35. Radiobiology of Lung Cancer 36. Patient Selection for Radiotherapy 37. Stage I Non-Small Cell Lung Cancer and Oligometastatic Disease 38. Ablation Options for Localized Lung Cancer 39. Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer, including Combined Modality 40. Radiotherapy in the Management of Small Cell Lung Cancer: Thoracic Radiotherapy, Prophylactic Cranial Irradiation 41. Palliative Radiotherapy for Lung Cancer: Locoregional and Metastatic 42. Acute and Late Toxicities of Thoracic Radiotherapy: Pulmonary, Esophagus, Heart 43. Treatment-Related Neurotoxicity, Medical and Radiation Therapy Section 9: Chemotherapy and Targeted Agents for Lung Cancer 44. Front-Line Systemic Options in Non-Small Cell Lung Cancer 45. Systemic Options in Second Line and Beyond 46. Maintenance Therapy in NSCLC 47. Pharmacogenomics and Lung Cancer 48. New Targetable Pathways in Lung Cancer 49. Management of Toxicities of Targeted Therapies 50. Immunotherapy and Lung Cancer 51. Systemic Therapy in Early-Stage NSCLC 52. Treatment of Small-Cell Lung Cancer Section 10: Other Thoracic Malignancies 53. Malignant Mesothelioma 54. Mediastinal Tumors 55. Neuroendocrine Tumors of the Lung Other than SCLC 56. Thymic Cancer/Thymoma Section 11: Symptom Management and Complications 57. Lung Cancer Emergencies 58. Role of Palliative Care in Lung Cancer Section 12: Clinical Trials 59. Methodology of Clinical Trials in Lung Cancer 60. How to Promote and Organize Clinical Research in Lung Cancer Section 13: Thoracic Oncology Advocacy 61. Role of Advocacy Groups in Lung Cancer 62. Health Services Research in Lung Cancer Appendix 63. Appendix: Diagnostic Algorithms.
  • (source: Nielsen Book Data)9780323523578 20170814
Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today's best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies.
(source: Nielsen Book Data)9780323523578 20170814