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1 online resource (xxi, 1714 pages) : illustrations (chiefly color)
  • Section 1: History of the Therapy of Breast Cancer 1. History of the Therapy of Breast Cancer Section 2: Anatomy and Physiology of the Normal and Lactating Breast 2. Anatomy of the Breast, Axilla, Chest Wall, and Related Metastatic Sites 3. Breast Physiology: Normal and Abnormal Development and Function 4. Discharges and Secretions of the Nipple Section 3: Benign and Premalignant Lesions 5. Etiology and Management of Benign Breast Disease 6. Mastitis and Breast Abscess 7. Gynecomastia 8. Benign, High-Risk, and Premalignant Lesions of the Breast Section 4: Pathology of Malignant Lesions 9. In Situ Carcinomas of the Breast: Ductal Carcinoma in Situ and Lobular Carcinoma in Situ 10. Infiltrating Carcinomas of the Breast: Not One Disease 11. Mesenchymal Neoplasms and Primary Lymphomas of the Breast 12. Paget Disease of the Breast 13. Primary and Secondary Dermatologic Disorders of the Breast 14. Breast Biomarker Immunocytochemistry Section 5: Natural History, Epidemiology, Genetics, and Syndromes of Breast Cancer 15. Epidemiology of Breast Cancer 16. Primary Prevention of Breast Cancer 17. Breast Cancer Genetics: Syndromes, Genes, Pathology, Counseling, Testing, and Treatment Section 6: Prognostic Factors for Breast Cancer 18. Clinically Established Prognostic Factors in Breast Cancer 19. Molecular Prognostic Factors for Breast Carcinoma 20. Risk Factors for Breast Carcinoma in Women with Proliferative Breast Disease 21. Steroid Receptors in Breast Cancer Section 7: Molecular Biology of Breast Carcinogenesis 22. Molecular Oncology of Breast Cancer 23. Stem Cells in Breast Development and Cancer 24. Therapeutic Strategies for Breast Cancer Section 8: Screening and Diagnosis of Breast Disease 25. Examination Techniques: Roles of the Physician and Patient in Evaluating Breast Disease 26. Breast Imaging Screening and Diagnosis Section 9: Clinical Trials: Biostatistical Applications 27. Design and Conduct of Clinical Trials for Breast Cancer Section 10: Surgery for Benign and Malignant Diseases of the Breast 28. Indications and Techniques for Biopsy 29. General Principles of Mastectomy: Evaluation and Therapeutic Options 30. Halsted Radical Mastectomy 31. Modified Radical Mastectomy and Simple Mastectomy 32. Breast Conservation Therapy for Invasive Breast Cancer Section 11: Breast Reconstruction 33. Breast Reconstruction Techniques Section 12: Complications of Breast Surgery 34. Wound Care and Complications of Mastectomy 35. Quality Measures and Outcomes for Breast Cancer Surgery 36. Lymphedema in the Postmastectomy Patient: Pathophysiology, Prevention, and Management Section 13: Current Concepts and Management of Early Breast Carcinoma (Tis, Tmic, T1) 37. Assessment and Designation of Breast Cancer Stage 38. Biology and Management of Lobular Carcinoma in Situ of the Breast (Lobular Neoplasia) 39. Ductal Carcinoma in Situ 40. The New Paradigm: Oncoplastic Breast Conservation Surgery 41. Therapeutic Value of Axillary Node Dissection and Selective Management of the Axilla in Small Breast Cancers 42. Lymphatic Mapping and Sentinel Lymphadenectomy for Breast Cancer 43. Detection and Significance of Axillary Lymph Node Micrometastases 44. Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy 45. Surgical Management of Early Breast Cancer Section 14: Therapy for Stages 0, I, and II Breast Cancer 46. Biologic Basis of Radiotherapy of the Breast 47. Radiotherapy and Ductal Carcinoma in Situ 48. Radiotherapy and Regional Nodes 49. Postmastectomy Radiotherapy 50. Breast-Conserving Therapy for Invasive Breast Cancers 51. Partial Breast Irradiation: Accelerated and Intraoperative 52. Radiation Complications and Their Management 53. Radiation Therapy for Locally Advanced Breast Cancer: Historical Review to Current Approach 54. Adjuvant Endocrine Therapy 55. Adjuvant and Neoadjuvant Systemic Therapies for Early Stage Breast Cancer 56. Adjuvant HER2 Therapy 57. Bisphosphonates in Early Breast Cancer 58. Oncofertility Options for Young Women with Breast Cancer Section 15: Management of Advanced Local, Regional, and Systemic Disease 59. Surgical Procedures for Advanced Local and Regional Malignancies of the Breast 60. Solitary Metastases 61. Locoregional Recurrence after Mastectomy 62. Principles of Preoperative Therapy for Operable Breast Cancer 63. Locally Advanced Breast Cancer 64. Inflammatory Breast Cancer 65. Neoadjuvant Chemotherapy and Radiotherapy 66. Detection and Clinical Implications of Occult Systemic Micrometastatic Breast Cancer 67. Management of the Intact Breast Primary in the Setting of Metastatic Disease 68. Management of Bone Metastases in Breast Cancer 69. Chemotherapy and HER2-Directed Therapy for Metastatic Breast Cancer 70. Endocrine Therapy for Breast Cancer 71. Immunologic Approaches to Breast Cancer Therapy 72. Diagnosis and Management of Pleural Metastases in Breast Cancer 73. Management of Central Nervous System Metastases in Breast Cancer 74. Management of Pericardial Metastases in Breast Cancer Section 16: Special Presentations of Breast Cancer 75. Bilateral Breast Cancer 76. Cancer of the Male Breast 77. Local Recurrence, the Augmented Breast, and the Contralateral Breast 78. Carcinoma of the Breast in Pregnancy and Lactation 79. Unknown Primary Presenting with Axillary Lymphadenopathy 80. Clinical Management of the Patient at Increased or High Risk Section 17: Survivorship, Follow-Up Care, and Rehabilitation of the Breast Cancer Patient 81. General Considerations for Follow-Up 82. Management of Menopause in the Breast Cancer Patient 83. Rehabilitation 84. Psychosocial Consequences and Lifestyle Interventions 85. Survivorship with Breast Cancer Section 18: Medical and Legal Issues Specific to the Care of Breast Cancer 86. Delayed Diagnosis of Symptomatic Breast Cancer.
  • (source: Nielsen Book Data)9780323359559 20171017
Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast cancer detection and treatment in a practical, easy-to-use format ideal for today's surgeons.Delivers step-by-step clinical guidance highlighted by superb illustrations that depict relevant anatomy and pathology, as well as medical and surgical procedures. Reflects the collaborative nature of diagnosis and treatment among radiologists, pathologists, surgeons, oncologists, and other health care professionals who contribute to the management of patients with breast disease. Offers the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast. Covers the latest developments in receptor modulation, targeted monoclonal antibodies, evolving inhibitors with triple-negative disease, and more. Discusses recent minimally invasive surgical techniques and new developments in oncoplastic breast conservation techniques. Contains significant updates to the "Management of Systemic Disease" section that reflect the latest advances in chemotherapy, hormonal resistance, and therapy. Includes links to real-time procedure videos and full-color procedural line drawings from the Klimberg Atlas of Breast Surgical Techniques on Expert Consult, providing expert visual guidance on how to execute key steps and techniques. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.
(source: Nielsen Book Data)9780323359559 20171017
1 online resource : illustrations (chiefly color)
  • Section 1 Structural and Molecular Bases of Ion Channel Function 1. Voltage-Gated Sodium Channels and Electrical Excitability of the Heart 2. Voltage-Gated Calcium 3. Voltage-Gated Potassium Channels 4. Structural and Molecular Bases of Cardiac Inward Rectifier Potassium Channel Function 5. Mammalian Calcium Pumps in Health and Disease 6. Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function 7. Organellar Ion Channels and Transporters 8. Molecular Organization, Gating and Function of Connexin-based Gap Junction Channels and Hemichannels Section 2 Biophysics of Cardiac Ion Channel Function 9. Structure-function relations of Heterotrimetric complexes of sodium channel a and � subunits 10. Regulation of Cardiac Calcium Channels 11. Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome 12. Structural Determinants and Biophysical Properties of hERG1 Channel Gating 13. Molecular Regulation of Cardiac Inward Rectifier Potassium Channels by Pharmacological Agents 14. Cardiac Stretch-Activated Channels and Mechano-Electric Coupling 15. Biophysical Properties of Gap Junctions 16. Excitation-Contraction Coupling Section 3 Intermolecular Interactions and Cardiomyocyte Electrical Function 17. Ion Channel Trafficking in the Heart 18. Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5 19. Fibroblast growth factor homologous factors modulate cardiac calcium channels. 20. Macromolecular Complexes and Cardiac Potassium Channels 21. Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias 22. The intercalated disc: A molecular network that integrates electrical coupling, intercellular adhesion and cell excitability 23. Function and dysfunction of ion channel membrane trafficking and post translational modification 24. Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling. Section 4 Cell Biology of Cardiac Impulse Initiation and Propagation 25. Stem cell-derived nodal-like cardiomyocytes as a novel pharmacologic tool: insights from sinoatrial node development and function. 26. Gene Therapy and Biological Pacing 27. Intercellular Communication and Impulse Propagation 28. Mechanisms of normal and dysfunctional Sinoatrial Nodal Excitability and Propagation 29. Cell Biology of the Specialized Cardiac Conduction System 30. Cardiac Remodeling and Regeneration Section 5 Models of Cardiac Excitation 31. Ionic Mechanisms of Atrial Action Potentials 32. Genetic algorithms to generate dynamical complexity electrophysiological models 33. Calcium Signaling in Cardiomyocyte Models with Realistic Geometries 34. Theory of Rotors and Arrhythmias 35. Computational approaches for Accurate Rotor localization in the Human Atria 36. Modeling the aging heart Section 6 Neural Control of Cardiac Electrical Activity 37. Innervation of the sinoatrial node 38. Mechanism for altered autonomic and oxidant regulation of cardiac sodium currents. 39. Pulmonary Vein Ganglia and the Neural Regulation of the Heart Rate 40. Neural Activity and Atrial Tachyarrhythmias 41. Sympathetic Innervation and Cardiac Arrhythmias Section 7 Arrhythmia Mechanisms 42. The Molecular Pathophysiology of Atrial Fibrillation 43. Myofibroblasts, Cytokines, and Persistent Atrial Fibrillation 44. Role of the Autonomic Nervous System in Atrial Fibrillation 45. Rotors in Human Atrial Fibrillation 46. Body surface frequency-phase mapping of atrial fibrillation. 47. Panoramic Mapping of Atrial Fibrillation from the body surface 48. Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation 49. Genetics of Atrial Fibrillation Section 8 Molecular Genetics and Pharmacogenomics 50. Mechanisms in Heritable Sodium Channel Diseases 51. Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes 52. Inheritable Potassium Channel Diseases 53. Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation Section 9 Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction 54. Pharmacologic Bases of Antiarrhythmic Therapy 55. Pharmacogenomics of Cardiac Arrhythmias 56. Gene therapy to treat cardiac arrhythmias 57. Highly Mature Human iPSC-Derived Cardiomyocytes as Models for Cardiac Electrophysiology and Drug Testing 58. Cardiac repair with human induced pluripotent stem cell-derived cardiovascular cells. Section 10 DIAGNOSTIC EVALUATION 59. Assessment of the patient with a cardiac arrhythmia 60. Electrocardiography of tachyarrhythmias: Differential diagnosis of narrow and wide QRS complex tachycardias 61. Electroanatomic Mapping for arrhythmias 62. Computed tomography for electrophysiology 63. Magnetic resonance imaging for electrophysiology 64. Intracardiac echocardiography for electrophysiology 65. Exercise-induced arrhythmias 66. Cardiac monitoring: short- and long-term recording 67. Head-up Tilt Table Testing 68. Autonomic Regulation and Cardiac Risk 69. T-wave alternans 70. Noninvasive Electrocardiographic Imaging of Human Ventricular Arrhythmias and Electrophysiological Substrate 71. Genetic testing Section 11 SUPRAVENTRICULAR TACHYARRHYTHIAS: MECHANISMS, CLINICAL FEATURES, AND MANAGEMENT 72. Sinus node abnormalities 73. Atrial tachycardia 74. Atrial tachycardia in adults with congenital heart disease 75. Typical and Atypical Atrial Flutter: Mapping and Ablation 76. Atrial fibrillation 77. Preexcitation, Atrioventricular reentry, Variants 78. Electrophysiological Characteristics of Atrioventricular Nodal Reentrant Tachycardia: Implications for the Rentrant Circuits 79. Junctional tachycardia Section 12 VENTRICULAR TACHYCARRHYTHMIAS: MECHANISMS, CLNICAL FEATURES, AND MANAGEMENT 80. Premature ventricular complexes 81. Outflow tract ventricular tachycardias: Mechanisms, Clinical Features, and Management 82. Fascicular ventricular arrhythmias 83. Bundle branch reentry tachycardia 84. Ischemic heart disease 85. Ventricular Tachycardia in Patients with Dilated Cardiomyopathy 86. Ventricular Arrhythmias in Hypertrophic Cardiomyopathy 87. Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy 88. VTs in Catcholaminergic Cardiomyopathy (Catecholaminergic polymorphic ventricular tachycardia) 89. Ventricular Arrhythmias in Heart failure 90. Arrhythmias and conduction disturbances in Non Compaction Cardiomyopathy 91. Takotsubo cardiomyopathy 92. Brugada syndrome 93. Long and short QT syndromes 94. Anderson-Tawil syndrome 95. Timothy syndrome 96. J Wave Syndromes 97. Idiopathic ventricular fibrillation 98. Sudden infant death syndrome 99. Sudden cardiac arrest/death in adults 100. Neurologic disorders 101. Drug-Induced Ventricular Tachycardia 102. Ventricular Arrhythmias in Congenital Heart Disease Section 13 SYNCOPE and Bradyarrhythmias 103. Syncope 104. Postural orthostatic tachycardia syndrome 105. Progressive conduction system disease 106. Atrioventricular block Section 14 ARRHYTHMIAS IN SPECIAL POPULATIONS PHARMACOLOGIC THERAPY 107. Sex differences in arrhythmias 108. Sudden cardiac death in athletes, inlcuding commotio cordis 109. Pediatric populations 110. Sleep-disordered breathing and arrhythmias 111. Ventricular Assist devices and Cardiac Transplantation Recipients Section 15 PHARMACOLOGIC THERAPY 112. Standard antiarrhythmic drugs 113. Innovations In Antiarrhythmic Drug Therapy 114. Nontraditional drugs for sudden cardiac death 115. Prevention of stroke in atrial fibrillation: warfarin, anti-factor Xa and thrombin drugs Section 16 CARDIAC IMPLANTABLE ELECTRONIC DEVICES 116. Implantable cardioverter defibrillators: technical aspects 117. Implantable cardioverter defibrillators: clinical aspects 118. Subcutaneous implantable defibrillator 119. Implantable pacemakers 120. Cardiac resynchronization therapy 121. Newer applications of pacemakers 122. Remote monitoring Section 17 CATHETER ABLATION 123. Catheter Ablation: Technical aspects 124. Catheter Ablation: Clinical aspects 125. Ablation for Atrial fibrillation 126. Ablation of Supraventricular tachycardias 127. Catheter Abliation for Ventricular tachycardias with/without structural heart disease 128. Epicardial and other approaches 129. Ventricular fibrillation 130. Ablation in Pediatrics 131. Congenital heart disease 132. Anesthesiology for EP procedures Section 18: SURGERY FOR ARRHYTHMIAS 133. Surgery for Atrial fibrillation and other supraventricular tachycardias 134. Surgery for Ventricular tachycardia Section 19 NEW APPROACHES 135. Cervical vagal stimulation for heart failure 136. Baroreflex stimulation 137. Spinal cord stimulation for heart failure and Arrhythmias 138. Renal artery denervation 139. Left atrial appendage occlusion/ligation.
  • (source: Nielsen Book Data)9780323447331 20170814
Rapid advancements in cardiac electrophysiology require today's health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field.
(source: Nielsen Book Data)9780323447331 20170814
1 online resource
Keeping up with the use of new technologies in cardiology is becoming increasingly challenging. Case Studies in Clinical Cardiac Electrophysiology helps to bridge the gap between knowledge and application with 28 cases spanning both common and uncommon arrhythmias and ablation scenarios, each of which includes the clinical presentation, baseline ECG, ECG during arrhythmia, stepwise electrophysiologic diagnostic maneuvers and some of their pitfalls, and optimal therapy. Online access to the complete contents ensures the information you need is right at your fingertips.
1 online resource (xix, 463 pages) : color illustrations.
1 online resource (xxii, 487 pages) : illustrations (some color)
  • Epidemiology of chronic coronary artery disease
  • The global perspective of ischemic heart disease
  • Genetics of coronary atherosclerosis
  • Basic mechanisms of atherosclerosis
  • Coronary microvascular dysfunction
  • Precipitants of myocardial ischemia
  • History and physical examination
  • Lipid measurements
  • Standard and novel biomarkers
  • ECG and standard exercise stress testing
  • Echocardiography
  • Nuclear imaging and pet
  • CT and MRI
  • Invasive testing
  • Putting it all together : which test for which patient?
  • Goals of therapy
  • Global risk assessment
  • Lifestyle interventions
  • Obesity and the obesity paradox
  • The medical treatment of stable angina
  • Antiplatelet and anticoagulant drugs
  • Prevention of sudden cardiac death
  • Revascularization approaches
  • Managing chronic coronary artery disease in patients with diabetes
  • Angina in patients with evidence of myocardial ischemia and no obstructive coronary artery disease
  • Depression, anxiety, and stress
  • Refractory angina
  • Primary prevention of atherosclerotic cardiovascular disease
  • Screening for atherosclerotic cardiovascular disease in asymptomatic individuals
  • Secondary prevention of coronary artery disease.
Featuring expert guidance from Drs. James de Lemos and Torbjorn Omland, as well as other globally known leaders in cardiology, Chronic Coronary Artery Disease covers every aspect of managing and treating patients suffering from chronic coronary syndromes. This brand-new companion to Braunwald's Heart Disease was designed as a stand-alone reference for physicians treating patients who present with complex, unique challenges, offering the latest information on the use of imaging modalities in diagnosis and treatment, advances in interventional and surgical approaches to revascularization, new medications to improve symptoms and outcomes in chronic CAD, and much more. Relevant updates to the text are sourced regularly from the parent reference, Braunwald's Heart Disease and delivered on Expert Consult at no additional cost. These updates cover late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald.
1 online resource. Digital: text file; PDF.
  • Chapter 1. Introduction and Biogeography (Jessica Halofsky, David Peterson, and Karen Dante-Wood).- Chapter 2. Climatology (Linda Joyce and Marian Talbert).- Chapter 3. Water Resources (Chales Luce).- Chapter 4. Fisheries (Michael Young and Daniel Isaak). - Chapter 5. Forest Vegetation (Robert Keane).- Chapter 6.- Non-Forest Vegetation (Matthew Reeves).- Chapter 7. Ecological Disturbance (Rachel Loehman).- Chapter 8. - Wildlife (Kevin McKelvey and Polly Buotte).- Chapter 9. Recreation (Michael Hand and Megan Lawson).- Chapter 10.- Ecosystem Services (Travis Warziniack).- Chapter 11. Cultural Resources (Carl Davis).- Chapter 12. Applications in Resource Management and Planning (Karen Dante-Wood and Linh Hoang).
  • (source: Nielsen Book Data)9783319569277 20171127
This book is the result of a team of approximately 100 scientists and resource managers who worked together for two years to understand the effects of climatic variability and change on water resources, fisheries, forest vegetation, non-forest vegetation, wildlife, recreation, cultural resources and ecosystem services. Adaptation options, both strategic and tactical, were developed for each resource area. This information is now being applied in the northern rocky Mountains to ensure long-term sustainability in resource conditions.The volume chapters provide a technical assessment of the effects of climatic variability and change on natural and cultural resources, based on best available science, including new analyses obtained through modeling and synthesis of existing data. Each chapter also contains a summary of adaptation strategies (general) and tactics (on-the-ground actions) that have been developed by science-management teams.
(source: Nielsen Book Data)9783319569277 20171127
1 online resource (xi, 631 pages) : illustrations (chiefly color)
  • Preinvasive disease of the cervix / L. Stewart Massad
  • Preinvasive disease of the vagina and vulva and related disorders / Cara A. Mathews and Joan L. Walker
  • Invasive cervical cancer / Krishnansu S. Tewari and Bradley J. Monk
  • Endometrial hyperplasia, estrogen therapy, and the prevention of endometrial cancer / Lisa M. Landrum, Rosemary E. Zuna, and Joan L. Walker
  • Adenocarcinoma of the uterine corpus / William T. Creasman and David Scott Miller
  • Sarcoma of the uterus / D. Scott McMeekin and William T. Creasman
  • Gestational trophoblastic disease / Emma L. Barber and John T. Soper
  • Invasive cancer of the vulva / Thomas Herzog
  • Invasive cancer of the vagina / Marilyn Huang, Brian M. Slomovitz, and Robert L. Coleman
  • The adnexal mass / Camille C. Gunderson, Robert S. Mannel, and Philip J. Di Saia
  • Epithelial ovarian cancer / Eric L. Eisenhauer, Ritu Salani, and Larry J. Copeland
  • Germ cell, stromal, and other ovarian tumors / Emily R. Penick, Chad Hamilton, G. Larry Maxwell, and Charlotte S. Marcus
  • Fallopian tube cancer / Erica R. Hope, G. Larry Maxwell, and Chad A. Hamilton
  • Breast diseases / Patricia A. Cronin and Mary L. Gemignani
  • Cancer in pregnancy / Krishnansu S. Tewari
  • Complications of disease and therapy / Kemi M. Doll, Daniel L. Clarke-Pearson
  • Basic principles of chemotherapy / Christina S. Chu and Stephen C. Rubin
  • Targeted therapy and molecular genetics / Shannon N. Westin, Anil K. Sood, and Robert L. Coleman
  • Genes and cancer : genetic counseling and clinical management / David G. Mutch, Sheri Babb, and Philip J. Di Saia
  • Palliative care and quality of life / Dana M Chase, Siu-Fun Wong, Lari Wenzel, and Bradley J. Monk
  • Role of minimally invasive surgery in gynecologic malignancies / Floor J. Backes, David E. Cohn, Robert S. Mannel, and Jeffrey M. Fowler
  • Epidemiology of commonly used statistical terms and analysis of clinical studies / Wendy R. Brewster
  • Basic principles in gynecologic radiotherapy / Catheryn M. Yashar
  • Appendices. Staging: staging of cancer at gynecologic sites
  • Modified from common terminology criteria for adverse events (common terminology criteria for adverse events)
  • Blood component therapy
  • Suggested recommendations for routine cancer screening
  • Nutritional therapy.
The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers - a must-have reference for improving outcomes and providing effective care. A "who's who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference.
(source: Nielsen Book Data)9780323400671 20170410
1 online resource.
  • Chapter 1: Pathophysiology of atherosclerosis Biology of the vessel wall Endothelial function Atherosclerotic plaque Risk factors (dyslipidemia, smoking, hypertension etc.) The role of inflammation The role of oxidative stress Genetics of atherosclerosis Chapter 2: Coronary artery circulation: Basic principles Functional anatomy Myocardial oxygen consumption Regulation of oxygen transport and coronary blood flow Stable angina pectoris Acute coronary syndromes Chapter 3: Novel and experimental therapies in advance atherosclerosis Anti-inflammatory treatments Anti-oxidant treatment Gene-therapy Stem-cell therapy Diagnostic strategies-novel imaging modalities-multimodalities and hybrid techniques Novel antiplatelet agents Primary percutaneous coronary intervention Novel developments in interventional strategies.
  • (source: Nielsen Book Data)9780128119082 20171204
Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management round out this comprehensive tome that is ideal for practitioners and researchers. By summarizing this novel knowledge and changes in diagnostic algorithm and treatment options, this is the perfect reference for cardiology researchers who want a volume with the most up-to-date experimental trends in the field of atherosclerosis, for cardiologists and physicians who manage patients with atherosclerotic risk factors and established coronary artery disease, and medical students who want to learn the basic concepts of atherosclerosis.
(source: Nielsen Book Data)9780128119082 20171204
xvii, 135 pages ; 23 cm.
  • Foreword Dr Richard Greenwood, Series foreword Barbara A Wilson, Acknowledgments, Preface, The start of the (almost) end, The most exciting day of my life, My boring history, The Wellington hospital, A second childhood, The wheelchair and me, Standing on two feet, Understanding and feeling, The Bleakness, Clothes make the man, A birthday in hospital, A tilted point of view, The assault on self , End of an era, The national health service, The death of ambition, Other peoples' stories, The Oliver Zangwill Centre, The idealism of youth, The land of OZ, Perfectionism, The rainbow, The importance of semantics, The traumatic brain injury fraternity, A return to the institution, Writing, Excuses and choices, A constructive pastime, An (almost) new start, Epilogue, A little bit about the author, Index, References, Further reading.
  • (source: Nielsen Book Data)9781138055650 20171017
Whilst preparing for his travel adventures into a world he had yet to explore, Christopher Yeoh was involved in a road traffic accident and experienced something few others would be "privileged" to witness. Eight days in a coma, more than a year in and out of hospital and a gradual re-introduction to the world of work. A Different Perspective After Brain Injury: A Tilted Point of View is written entirely by the survivor, providing an unusually introspective and critical personal account of life following a serious blow to the head. It charts the initial insult, early rehabilitation, development of understanding, the return of emotion, moments of triumph and regression into depression, the exercise of reframing how a brain injury is perceived and a return to work. It also describes the mental adjustments of awareness and acceptance alongside the physical recovery process. Readily accessible to the general public, this book will also be of particular interest to professionals involved in the care of people who have had significant brain injuries, brain injury survivors, their families and friends and also those who fund and organise health and social care. This unique author account will provide a degree of understanding of what living with a hidden disability is really like.
(source: Nielsen Book Data)9781138055650 20171017
Green Library
1 electronic resource.
  • Chapter 1. Epidemiology of drug allergy
  • Chapter 2. Economic impact of drug allergy
  • Chapter 3. Drug allergy: definitions and phenotypes
  • Chapter 4. Immune mechanisms of drug allergy
  • Chapter 5. Pharmacogenomics of drug allergy
  • Chapter 6. Cutaneous reactions to drugs
  • Chapter 7. Basics of skin testing and drug challenges
  • Chapter 8. In vitro and in vivo tests for drug hypersensitivity reactions
  • Chapter 9. Drug desensitization
  • Chapter 10. Penicillins
  • Chapter 11. Cephalsporin allergy
  • Chapter 12. Macrolide allergy
  • Chapter 13. Quinolone allergy
  • Chapter 14. Sulfonamide drug allergy
  • Chapter 15. Other antibiotic allergy
  • Chapter 16. Multiple drug intolerance syndrome
  • Chapter 17. Aspirin-exacerbated respiratory disease
  • Chapter 18. Other NSAIDs reactions
  • Chapter 19. Chemotherapy allergy
  • Chapter 20. Hypersensitivity reactions to monoclonal antibodies
  • Chapter 21. Perioperative allergy
  • Chapter 22. Adverse reactions to contrast media
  • Chapter 23. Corticosteroids
  • Index.
1 online resource.
  • Section 1 - Endoscoping liver patients: safety issues 1. Equipment, sterilisation and training issues 2. Sedation and analgesia in liver disease 3. Endoscopy and coagulation abnormalities in the liver patient 4. Patients with specific aetiologies (viral, bariatric, nafld, vcjd, alcohol) Section 2 - Endoscopic management of portal hypertension 4. Diagnosis and staging of oesophagogastric varices 5. Endoscopic management of acute variceal bleeding 6. Primary and secondary variceal prophylaxis: role of endoscopy 7. Refractory variceal bleed: when endoscopy fails what next?: 8. Gastropathy and gastric vascular ectasias in portal hypertension 9. Portal hypertensive enteropathy and colopathy 10. Endoscopic ultrasound in the diagnosis and management of portal hypertension 11. Wireless capsule endoscopy in liver disease Section 3 - Endoscopic diagnosis and management of gastrointestinal pathology in the liver patient 12. Common gastrointestinal pathology in the liver patient (barrett s, pud, gastropathy, celiac, polypoid lesions) 13. Anaemia and obscure gi bleed in the liver patient 14. ERCP and cholangioscopy in hepatobiliary disease 15. EUS in the diagnosis of hepatobiliary malignancy 16. Endomicroscopy in the diagnosis of hepatobiliary disease 17. Laparoscopy in patients with hepatobiliary disease Section 4 - Endoscopy in the liver transplant patient 18. Endoscopy of the liver patient prior to liver transplantation 19. Endoscopy of the post- liver transplant patient 20.luminal diseases in the liver transplant patient.
  • (source: Nielsen Book Data)9781118660799 20171121
Liver disease is an increasingly common cause of mortality, and its management is often complex and challenging. Endoscopy has in recent times undergone a period of rapid progress, with numerous novel and specialized endoscopic modalities that are of increasing value in the investigation and management of the patient with liver disease. As the technology in endoscopy expands, both as a diagnostic and interventional procedure, so does the role of the endoscopist in liver disease. This full colour book and companion website offer a comprehensive guidance as to when, why, and how to perform endoscopy to best manage your patients. Brings together two key areas liver disease and endoscopy into one expert clinical textbookCovers the entire spectrum of clinical problems that gastroenterologists and endoscopists face while managing patients with liver diseaseIncludes the latest management guidelines from the key international societies, such as the ASGE, AASLD, EASL and BSGWell illustrated with over 150 high-quality colour images11 high-quality videos illustrating optimum endoscopy practice, all clearly referenced in the text An indispensable tool for all gastroenterologists, hepatologists and endoscopists, Endoscopy in Liver Disease is perfect for learning how to perform endoscopy safely and effectively in the patient population with liver disorders.
(source: Nielsen Book Data)9781118660799 20171121
21 PDFs (xxxvii, 349 pages) : illustrations
  • Chapter 1. Medical students' quest towards the long white coat: impact on mental health and well-being
  • Chapter 2. Medical students' perceived stigma in seeking care: a cultural perspective
  • Chapter 3. Perfectionism: addressing lofty expectations in medical school
  • Chapter 4. Medical student burnout: a social cognitive learning perspective on medical student mental health and wellness
  • Chapter 5. Deliberate self-harm and suicide ideology in medical students
  • Chapter 6. From medical student to medical resident: graduate medical education and mental health in the United States
  • Chapter 7. Resident physician and medical academic faculty burnout: a review of current literature
  • Chapter 8. Developing a comprehensive wellness program for medical students
  • Chapter 9. Medical school wellness initiatives
  • Chapter 10. Essentials for education and training for tomorrow's physicians.
Discussions surrounding mental health are becoming more prominent and these conditions are becoming less stigmatized. Studying the effects that mental wellness has on students within the medical field can provide an insider perspective on this critical topic. Exploring the Pressures of Medical Education From a Mental Health and Wellness Perspective is a critical reference source that examines the mental and emotional problems that arise with students practicing in the medical field. Featuring relevant topics such as student burnout, cognitive learning, graduate education, and curriculum development, this scholarly publication is ideal for medical practitioners, academicians, students, and researchers that are interested in staying apprised of the latest trends and developments relating to mental wellness.
(source: Nielsen Book Data)9781522528128 20171211
1 online resource.
  • The cardiac electrical system
  • Abnormal heart rhythms
  • Treatment of arrhythmias
  • The electrophysiology study in the evaluation and therapy of cardiac arrhythmias
  • Principles of the electrophysiology study
  • The electrophysiology study in the evaluation of bradycardia : the SA node AV node and his purkinje system
  • The electrophysiology study in the evaluation of supraventricular tachyarrhythmias
  • The electrophysiology study in the evaluation and treatment of ventricular arrhythmias
  • Transcatheter ablation : therapeutic electrophysiology
  • Ablation of supraventricular tachycardias
  • Ablation of PVCS and ventricular tachycardia
  • Ablation of atrial fibrillation
  • Ablation of atrial flutter
  • Cardiac resynchronization : pacing therapy for heart failure
  • The evaluation of syncope
  • Electrophysiologic testing in perspective : the evaluation and treatment of cardiac arrhythmias.
1 online resource (ix, 260, e98 pages) : illustrations (some color)
  • PART ONE: Basic Principles and Patterns * Essential Concepts: What is an ECG? * ECG Basics: Waves, Intervals, and Segments * How to Make Basic Measurements * ECG Leads * The Normal ECG * Electrical Axis and Axis Deviation * Atrial and Ventricular Enlargement * Ventricular Conduction Disturbances: Bundle Branch Blocks and Related Abnormalities * Myocardial Infarction and Ischemia, Part I: ST Segment Elevation and Q Wave Syndromes * Myocardial Infarction and Ischemia, Part II: Non-ST Segment Elevation and Non-Q Wave Syndromes * Drug Effects, Electrolyte Abnormalities, and Metabolic Effects * Pericardial, Myocardial, and Pulmonary Syndromes PART TWO: Cardiac Rhythm Disturbances 13. Sinus and Escape Rhythms 14. Supraventricular Arrhythmias, Part I: Premature Beats and Paroxysmal Supraventricular Tachycardias (PSVTs) 15. Supraventricular Arrhythmias, Part II: Atrial Flutter and Atrial Fibrillation 16. Ventricular Arrhythmias 17. AV Conduction Abnormalities, Part I: Delays, Blocks, and Dissociation Syndromes 18. AV Conduction Abnormalities, Part II: Preexcitation (Wolff-Parkinson-White) Patterns and Syndromes PART THREE: Special Topics and Reviews 19. Bradycardias and Tachycardias: Review and Differential Diagnosis 20. Digitalis Toxicity 21. Sudden Cardiac Arrest and Sudden Cardiac Death 22. Pacemakers and Implantable Cardioverter-Defibrillators: Essentials for Clinicians 23. Interpreting ECGs: An Integrative Approach 24. Limitations and Uses of the ECG 25. ECG Differential Diagnoses: Instant Replays.
  • (source: Nielsen Book Data)9780323401692 20170612
Ideal for students and as a review for practicing clinicians, Goldberger's Clinical Electrocardiography explains the fundamentals of ECG interpretation and analysis, helping facilitate an understanding of rhythm disorders and the relevant clinical outcomes. The authors take readers through the nuts and bolts of ECG, using Dr. Ary Goldberger's award-winning teaching style to clarify complex concepts in an easy-to-read manner. You'll learn simple waveform analysis and beyond to present ECGs as they are used in hospital wards, outpatient clinics, emergency departments, and most especially intensive care units - where the recognition of normal and abnormal patterns is the starting point in patient care.
(source: Nielsen Book Data)9780323401692 20170612
1 online resource.
  • Heart Failure Epidemiology Chapter 1 Introduction Chapter 2 Pathophysiology and Risk Profiles of Heart Failure Chapter 3 Research and Design Chapter 4 Biostatistical Basis of Inference in Heart Failure Study Chapter�5 Advanced Biostatistics and Epidemiology Applied in Heart Failure Study Chapter 6 Precision Medicine and Areas for Further Research INDEX.
  • (source: Nielsen Book Data)9780323485586 20171204
Get a quick, expert overview of the many key facets of heart failure research with this concise, practical resource by Dr. Longjian Liu. This easy-to-read reference focuses on the incidence, distribution, and possible control of this significant clinical and public health problem which is often associated with higher mortality and morbidity, as well as increased healthcare expenditures. This practical resource brings you up to date with what's new in the field and how it can benefit your patients.Features a wealth of information on epidemiology and research methods related to heart failure. Discusses pathophysiology and risk profile of heart failure, research and design, biostatistical basis of inference in heart failure study, advanced biostatistics and epidemiology applied in heart failure study, and precision medicine and areas of future research. Consolidates today's available information and guidance in this timely area into one convenient resource.
(source: Nielsen Book Data)9780323485586 20171204
1 online resource (xvi, 425 pages) : illustrations (some color).
1 online resource : illustrations (chiefly color)
  • SECTION I: EPIDEMIOLOGY 1. General Population and Global Cardiovascular Risk Prediction 2. Hypertension in Latin/Hispanic Population 3. Hypertension in East Asians and Native Hawaiians 4. Hypertension in South Asians SECTION II: PATHOPHYSIOLOGY 5. Pathogenesis of Hypertension 6. Genetics of Hypertension 7. Inflammation and Immunity in Hypertension SECTION III: DIAGNOSIS AND EVALUATION 8. The Environment and High Blood Pressure 9. Office Blood Pressure Measurement 10. Home Monitoring of Blood Pressure 11. Ambulatory Blood Pressure Monitoring in Clinical Hypertension Management 12. White Coat and Masked Hypertension 13. Renovascular Hypertension and Ischemic Nephropathy 14. Secondary Hypertension: Primary Hyperaldosteronism and Mineralocorticoid Excess States 15. Secondary Hypertension: Pheochromocytoma and Paraganglioma 16. Secondary Hypertension: Sleep Disturbances including Sleep Apnea 17. Hypertension in Children: Diagnosis and Treatment SECTION IV: RISK STRATIFICATION 18. Natural History of Untreated Hypertension 19. Isolated Systolic Hypertension 20. Assessment of Target Organ Damage SECTION V: ANTIHYPERTENSIVE THERAPY 21. Diet and Blood Pressure 22. Diuretics in Hypertension 23. Alpha Blockers and Hypertension 24. Renin Angiotensin Aldosterone System Blockers 25. Calcium Channel Blockers 26. Central Sympathetic Agents and Direct Vasodilators 27. Use of Combination Therapies 28. Devices Therapies 29. Alternative Approaches for Lowering Blood Pressure SECTION VI: HYPERTENSION MANAGEMENT 30. Approach to Difficult to Manage Primary Hypertension 31. Hypertension in Ischemic Heart Disease 32. Heart Failure 33. Hypertension and Chronic Kidney Disease 34. Transplant Hypertension 35. Obesity 36. Cerebrovascular Disease 37. Diabetes Mellitus 38. Dyslipidemia SECTION VII: SPECIAL POPULATIONS AND SPECIAL SITUATIONS 39. Hypertension in Pregnancy 40. Hypertension in Older People 41. Hypertension in African Americans 42. Baroreceptor Dysfunction/Orthostatic Hypotension 43. Resistant Hypertension 44. Hypertension and the Perioperative Period 45. Aorta and Peripheral Arterial Disease in Hypertension 46. Hypertensive Emergencies and Urgencies SECTION VIII: OUTCOME TRIALS 47. Meta-Analyses of Blood Pressure Lowering Trials and the Blood Pressure Lowering Treatment Trialists' Collaboration SECTION IX: HYPERTENSION TREATMENT IN THE FUTURE 48. Team-Based Care for Hypertension Management 49. Understanding and Improving Medication Adherence SECTION X: GUIDELINES 50. Updated AHA/ACC-- ESH/ISH 51. Putting All Guidelines into Perspective.
  • (source: Nielsen Book Data)9780323429733 20170410
The third edition of Hypertension: A Companion to Braunwald's Heart Disease, by Drs. George L. Bakris and Matthew Sorrentino, focuses on every aspect of managing and treating patients who suffer from hypertensive disorders. Designed for cardiologists, endocrinologists and nephrologists alike, this expansive, in-depth review boasts expert guidance from contributors worldwide, keeping you abreast of the latest developments from basic science to clinical trials and guidelines. Hypertension also includes an Expert Consult eBook updated with late-breaking clinical trials, reviews of important new articles, and the latest guidance on clinical practice, all selected and masterfully edited by Dr. Eugene Braunwald.
(source: Nielsen Book Data)9780323429733 20170410
1 online resource (xiii, 658 pages) : illustrations (some color), color map
  • Section 1: Lung Cancer Control and Epidemiology 1. Classical Epidemiology 2. Tobacco Control and Primary Prevention 3. Tobacco Cessation 4. Non-Smoking Related Lung Cancer 5. Gender-Related Differences in Lung Cancer 6. Genetic Susceptibility to Lung Cancer 7. Early Detection and Radiologic Screening 8. Preclinical Biomarkers for The Early Detection of Lung Cancer 9. Chemoprevention of Lung Cancer: Present and Developing Technologies Section 2: Lung Cancer Molecular Carcinogenesis 10. Copy Number Abnormalities and Gene Rearrangements in Lung Cancer: Present and Developing Technologies 11. Mutational Events in Lung Cancer: Present and Developing Technologies 12. Epigenetic Events, Alterations, and Remodeling in Lung Cancer: Present and Developing Technologies 13. Stem Cells and Lung Cancer: In Vitro and In Vivo Studies 14. Microenvironment and Lung Cancer 15. MicroRNAs as Biomarkers for Lung Cancer Section 3: Immunology 16. Humoral and Cellular Immune Dysregulation and Lung Cancer Section 4: Pathology 17. Classic Anatomic Pathology and Lung Cancer 18. Molecular Testing and Lung Cancer 19. Management of the Small Biopsy in the Molecular Er Section 5: Clinical and Radiologic Presentation of Lung Cancer 20. Clinical Presentation 21. Conventional Imaging Lung Cancer 22. PET Imaging of Lung Cancer Section 6: Diagnosis and Staging of Lung Cancer 23. Diagnostic Work-Up of Suspected Lung Cancer 24. Surgical Staging of the Mediastinum including Mediastinoscopy and Thoracoscopy, Preoperative and Intraoperative 25. The 8th Edition of the Tumor, Node and Metastasis Classification of Lung Cancer Section 7: Surgical Management of Lung Cancer 26. Preoperative Functional Evaluation of the Surgical Candidate 27. Results of Video Assisted Techniques for Resection of Lung Cancer 28. Results of Robotic Techniques for Resection of Lung Cancer 29. Extent of Surgical Resection for Stage I and II Lung Cancer 30. Extended Resections for Lung Cancer: Chest Wall and Pancoast Tumors 31. Extended Resections for Lung Cancer: Broncho/Vascular Sleeve Resections 32. Multiple Nodules: Management of the Patient with Synchronous or Metachronous Lung Cancers 33. Surgical Management of the Marginally Resectable Patient Section 8: Radiotherapeutic Management of Lung Cancer 34. Technical Requirements for Lung Cancer Radiotherapy 35. Radiobiology of Lung Cancer 36. Patient Selection for Radiotherapy 37. Stage I Non-Small Cell Lung Cancer and Oligometastatic Disease 38. Ablation Options for Localized Lung Cancer 39. Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer, including Combined Modality 40. Radiotherapy in the Management of Small Cell Lung Cancer: Thoracic Radiotherapy, Prophylactic Cranial Irradiation 41. Palliative Radiotherapy for Lung Cancer: Locoregional and Metastatic 42. Acute and Late Toxicities of Thoracic Radiotherapy: Pulmonary, Esophagus, Heart 43. Treatment-Related Neurotoxicity, Medical and Radiation Therapy Section 9: Chemotherapy and Targeted Agents for Lung Cancer 44. Front-Line Systemic Options in Non-Small Cell Lung Cancer 45. Systemic Options in Second Line and Beyond 46. Maintenance Therapy in NSCLC 47. Pharmacogenomics and Lung Cancer 48. New Targetable Pathways in Lung Cancer 49. Management of Toxicities of Targeted Therapies 50. Immunotherapy and Lung Cancer 51. Systemic Therapy in Early-Stage NSCLC 52. Treatment of Small-Cell Lung Cancer Section 10: Other Thoracic Malignancies 53. Malignant Mesothelioma 54. Mediastinal Tumors 55. Neuroendocrine Tumors of the Lung Other than SCLC 56. Thymic Cancer/Thymoma Section 11: Symptom Management and Complications 57. Lung Cancer Emergencies 58. Role of Palliative Care in Lung Cancer Section 12: Clinical Trials 59. Methodology of Clinical Trials in Lung Cancer 60. How to Promote and Organize Clinical Research in Lung Cancer Section 13: Thoracic Oncology Advocacy 61. Role of Advocacy Groups in Lung Cancer 62. Health Services Research in Lung Cancer Appendix 63. Appendix: Diagnostic Algorithms.
  • (source: Nielsen Book Data)9780323523578 20170814
Global experts, in conjunction with the International Association for the Study of Lung Cancer, bring you up to date with today's best approaches to lung cancer diagnosis, treatment, and follow-up. IASLC Thoracic Oncology, 2nd Edition, keeps you abreast of the entire scope of this fast-changing field, from epidemiology to diagnosis to treatment to advocacy. Written in a straightforward, practical style for the busy clinician, this comprehensive, multidisciplinary title is a must-have for anyone involved in the care of patients with lung cancer and other thoracic malignancies.
(source: Nielsen Book Data)9780323523578 20170814
1 online resource : illustrations (some color)
  • Chapter 1: The Basics of Percutaneous Coronary Interventions Chapter 2: Vascular Access, Chapter 3: Interventional Pharmacology Chapter 4: Intravascular Lesion Assessment - Physiology and Imaging Chapter 5: Adjunctive Devices -Non-Balloon Coronary Interventional Techniques and Devices: Rotational Atherectomy, Thrombectomy, Cutting Balloons, and Embolic Protection Chapter 6: Stents, Restenosis, and Stent Thrombosis Chapter 7: Treatment of Coronary Bifurcations Chapter 8: Chronic Total Occlusions Chapter 9: High Risk Patients and Interventions Chapter 10: Complications of Percutaneous Coronary Interventions Chapter 11: Peripheral Vascular Intervention Chapter 12: Aortic, Renal, Subclavian and Carotid Interventions Chapter 13: Mitral Stenosis Chapter 14: Mitral Regurgitation Chapter 15: Transcatheter Aortic Valve Replacement and Balloon Aortic Valvuloplasty Chapter 16: Congenital Defects Chapter 17: Pericardiocentesis Chapter 18: Septal Ablation for Obstructive Hypertrophic Cardiomyopathy Chapter 19: Percutaneous Repair of Paravalvular Prosthetic Regurgitation Chapter 20: Left Atrial Appendage Therapies.
  • (source: Nielsen Book Data)9780323476713 20170814
Packed with useful information, The Interventional Cardiac Catheterization Handbook, 4th Edition, by Drs. Morton J. Kern, Michael J. Lim, and Paul Sorajja, is the perfect hands-on resource for physicians, nurses, and technicians who need to understand and perform these complex procedures. Easy-to-read text, hundreds of clear images, and narrated videos from Dr. Kern ensure that health care workers at all levels have quick access to easily accessible guidelines on procedures and patient care.
(source: Nielsen Book Data)9780323476713 20170814
1 online resource : illustrations
  • 1. Coronary Artery Disease2. Mitral Valve Disease3. Aortic Valve Disease4. Right-sided Valve Disease5. Endocarditis6. Adult Congenital Heart Disease7. Hypertrophic Cardiomyopathy8. Pericardial Disease9. Pulmonary Artery Surgery10. Aortic Disease11. Devices and Catheters12. Masses.
  • (source: Nielsen Book Data)9780323358255 20170911
Case-based and heavily illustrated, Intraoperative and Interventional Echocardiography: Atlas of Transesophageal Imaging, 2nd Edition covers virtually every clinical scenario in which you're likely to use TEE. Drs. Donald C. Oxorn and Catherine M. Otto provide practical, how-to guidance on transesophageal echocardiography, including new approaches and state-of-the-art technologies. More than 1,500 images and accompanying videos sharpen your image acquisition and analysis skills and help you master this challenging technique.
(source: Nielsen Book Data)9780323358255 20170911
1 online resource
  • List of Contributors xiii Preface xvii Cancer Genetics, Cancer Biology, and Tumor Growth and Metastasis: The Interaction of Cancer and Its Host Environment 1 Mark C. Markowski and Kenneth J. Pienta Renal Cell Carcinoma 1 Bladder Cancer 3 Prostate Cancer 6 References 12 Pathological Basis of Tumor Characterization: Cytopathology, Surgical Pathology, and How Histo ]Morphology Informs Treatment Decision Making 19 Oleksandr N. Kryvenko and Fadi Brimo The Kidney 23 The Urothelium 27 The Testis 29 References 30 The Immunobiology of Tumor Ablation 33 Rafi Kabarriti and Chandan Guha Manipulating the Immune System to Fight Cancer 33 Can We Take Advantage of Ablative Therapies to Activate the Immune System? 34 Immunomodulatory Properties of HIFU 35 Immunomodulatory Properties of Cryotherapy 36 Immunomodulatory Properties of Radiation Therapy 37 References 38 Computed Tomography of Urologic Malignancies: The Role of MDCT in Renal Cell Carcinoma and Transitional Cell Carcinoma 41 Siva P. Raman and Elliot K. Fishman Introduction 41 MDCT Protocol Design 41 Three ]Dimensional Reconstructions 44 Neoplasms of the Intrarenal Collecting Systems, Ureters, and Bladder 45 Solid Renal Parenchymal Lesions 49 Conclusion 55 References 55 MRI and Metabolic Imaging 59 Louise Dickinson, Francesco Fraioli, Athar Haroon, and Clare Allen Magnetic Resonance Imaging 59 MRI Sequences 59 Clinical Applications of MRI for Prostate Cancer 61 Clinical Applications of MRI for Renal Cancer 63 Clinical Applications of MRI for Bladder Cancer 64 New Advances in MRI 65 Metabolic Imaging 66 Clinical Applications of PET CT for Prostate Cancer 69 Active Surveillance for Low ]Risk Prostate Cancer 113 Laurence Klotz Introduction and Background 113 Rationale 113 Genetic Features of Low ]Grade Prostate Cancer 114 Metastatic Potential 115 Limitations of PSA Kinetics 116 Role of MRI 116 Implications for Patient Management 117 Eligibility for Surveillance 118 Outcome of Surveillance 119 Modeling 119 AS in Practice 121 Conclusions 121 References 122 Tissue ]Preserving Surgical Approaches in Urologic Oncology: The Therapeutic Mechanism for Tumor Ablation 127 Ganesh Kartha and J. Stephen Jones Introduction 127 Cryoablation: Extreme Cold for Tumor Necrosis 128 Conclusion 130 References 130 Focal Therapy for Prostate Cancer: An Evidence ]Based Approach to Tissue ]Preserving Strategies 133 Kara L. Watts, Yaalini Shanmugabavan, Victoria Chernyak, and Hashim Uddin Ahmed Introduction 133 Key Concepts in FT for PCa 134 Tissue ]Preserving FTs 135 Cryotherapy 135 HIFU 137 Salvage Focal/Hemiablation HIFU 140 IRE 141 Radiation 142 Additional Therapies 143 Implications for Research 144 Conclusions 144 References 145 The Modern Basis for Nephron ]Sparing Surgery in Patients with Renal Cancer: Biologic Heterogeneity, the Significance of Tumor Biopsy, and the Changing Roles of Partial Nephrectomy and Tumor Ablation 151 Jeffrey J. Tomaszewski, Robert G. Uzzo, and David Y.T. Chen Introduction 151 Principal Treatment Options for SRMs and the Basis for Nephron Preservation 152 Comparative Effectiveness of Radical versus NSS 153 Rationale for Ablative Therapies 154 Treatment Trends for Stage I RCC 157 The Role of RMB 158 Challenges Posed by Intratumoral Heterogeneity 161 Conclusions 161 References 162 Bladder ]Preserving Strategies in the Treatment of Urothelial Cancer: The Disease Spectrum and the Dawn of Molecular Surgical Guidance 169 Stephan Kruck and Arnulf Stenzl Augmented Cystoscopy 170 Fiber ]Optic Probe Technology 171 Conclusion 172 References 172 Image ]Guided Thermal Ablation of Adrenal Malignancies 175 Kyungmouk Steve Lee, Bradley B. Pua, and Stephen B. Solomon Introduction 175 Clinical Results 175 Preprocedural Evaluation 176 Technical Considerations 178 RFA 178 Microwave Ablation 179 Cryoablation 180 Complications 180 Follow ]up 181 Conclusion 182 References 182 Managing Penile Cancer: Integrating Tissue Preservation, Energy ]Based Therapeutics, and Surgical Reconstruction 185 Arthur L. Burnett Introduction 185 Description 186 Diagnosis and Staging 186 Treatment 189 References 193 Testis Cancer: Testis ]Sparing Cancer Surgery 199 Nilay M. Gandhi and Pravin K. Rao Introduction 199 Imaging of Testicular Tumors 199 Bilateral Tumors 201 The Advent of Testis ]Sparing Surgery 201 Concerns about TSS 201 Indications for TSS 204 Preoperative Considerations and Surgical Technique 204 Postoperative Care and Follow ]Up 207 Considerations Regarding Surgical Technique 207 Outcomes of TSS 208 Summary 209 References 210 Nanotechnology: An Evolution in Tissue Preservation and Focal ]Targeted Oncologic Therapy 213 Kara L. Watts and Joshua M. Stern Introduction 213 Introduction to Nanotechnology 214 Types of Nanoparticles 214 Delivery and Use of Nanoparticles 217 Nanotechnology in Prostate Cancer 219 Imaging in Prostate Cancer 219 Therapeutics in Prostate Cancer 221 Nanotechnology in Renal Cancer 223 Nanotechnology in Other Urologic Cancers 224 Limitations of Nanoparticles 224 Future Directions and Conclusions 225 References 226 Trial Design Issues in the Study of Focal Therapy in Prostate and Kidney Cancer 233 John B. Eifler and David F. Penson Issues around Endpoints in Studies of Focal Therapy 234 Issues around Defining the Study Population and the Control Arms of Comparative Studies in Focal Therapy 237 Issues around Selecting the Optimal Study Design in Focal Therapy 238 Conclusion 238 References 239 Index 000.
  • (source: Nielsen Book Data)9781118864623 20170626
Managing urologic cancer by preserving, as opposed to removing, affected tissue, is rapidly becoming the favoured choice for urologists and oncologists. Discover all available options and how to achieve the best possible patient management with this expert guide to the area. The editor, Mark Schoenberg, is an internationally-renown expert in this exciting new area and has recruited an outstanding team featuring some of the leading urologists/oncologists in North America and Europe to assist him.
(source: Nielsen Book Data)9781118864623 20170626
xv, 168 pages ; 28 cm.
  • Introduction Acknowledgements List of abbreviations Companion website Anatomical and functional organization 1 Development of the nervous system 2 Organization of the nervous system 3 Autonomic nervous system 4 Enteric nervous system 5 Meninges and cerebrospinal fluid 6 Blood supply to the central nervous system 7 Cranial nerves 8 Anatomy of the brainstem 9 Organization of the spinal cord 10 Organization of the cerebral cortex and thalamus 11 Hypothalamus Cells and neurophysiology 12 Cells of the nervous system I: neurones 13 Cells of the nervous system II: neuroglial cells 14 Ion channels 15 Resting membrane and action potential 16 Neuromuscular junction and synapses 17 Nerve conduction and synaptic integration 18 Neurotransmitters, receptors and their pathways 19 Main CNS neurotransmitters and their function 20 Skeletal muscle structure 21 Skeletal muscle contraction Sensory systems 22 Sensory systems: an overview 23 Sensory transduction 24 Visual system I: the eye and retina 25 Visual system II: the visual pathways and subcortical visual areas 26 Visual system III: visual cortical areas 27 Auditory system I: the ear and cochlea 28 Auditory system II: auditory pathways and language 29 Vestibular system 30 Olfaction and taste 31 Somatosensory system 32 Pain systems I: nociceptors and nociceptive pathways 33 Pain systems II: pharmacology and management 34 Association cortices: the posterior parietal and prefrontal cortex Motor systems 35 Organization of the motor system 36 Muscle spindle and lower motor neurone 37 Spinal cord motor organization and locomotion 38 Cortical motor areas 39 Primary motor cortex 40 Basal ganglia: anatomy and physiology 41 Basal ganglia: diseases and their treatments 42 Cerebellum Cognition and neural plasticity 43 Reticular formation and sleep 44 Limbic system and long-term potentiation 45 Memory 46 Emotion, motivation and drug addiction 47 Neural plasticity and neurotrophic factors I: the peripheral nervous system 48 Neural plasticity and neurotrophic factors II: the central nervous system 49 Techniques for studying the nervous system Applied neurobiology: the principles of neurology and psychiatry 50 Approach to the patient with neurological problems 51 Examination of the nervous system 52 Investigation of the nervous system 53 Imaging of the central nervous system 54 Clinical disorders of the sensory systems 55 Clinical disorders of the motor systems 56 Eye movements 57 Neurochemical disorders I: affective disorders 58 Neurochemical disorders II: schizophrenia 59 Neurochemical disorders III: anxiety 60 Neurodegenerative disorders 61 Neurophysiological disorders: epilepsy 62 Neuroimmunological disorders 63 Neurogenetic disorders 64 Cerebrovascular disease 65 Neuroradiological anatomy History of neuroscientific discoveries 66 Historical neuroscience discoveries Self-assessment case studies Case studies and questions Answers Index.
  • (source: Nielsen Book Data)9781119168416 20171204
Everything you need to know about Neuroanatomy and Neuroscience at a Glance! Neuroanatomy and Neuroscience at a Glance is a highly illustrated, quick reference guide to the anatomy, biochemistry, physiology and pharmacology of the human nervous system. Each chapter features a summary of the anatomical structure and function of a specific component of the central nervous system, a section on applied neurobiology outlining how to approach a patient with neurological or psychiatric problems aligned to the chapter topic, standard diagnostic procedures for most common scenarios, as well as an overview of treatment and management options. This fully updated and expanded new edition includes: Dozens of full-page, colour illustrations and neurological scansExpanded coverage of techniques to study the nervous systemMore practical information on the neurological examNew content on neuropharmacology and drug therapiesBullet points and bold terms throughout assist with revision and review of the topic Neuroanatomy and Neuroscience at a Glance is the ideal companion for students embarking on a neuroanatomy or neuroscience course, and is an excellent reference tool for those in clinical training.An updated companion website with new clinical cases, multiple choice self-assessment questions, revision slides, and downloadable illustrations and flashcards is available at www.ataglanceseries.com/neuroscience.
(source: Nielsen Book Data)9781119168416 20171204
Science Library (Li and Ma)
xi, 248 pages ; 24 cm.
  • Introduction 1. Printed Plague Literature in the Late Middle Ages, 1473-1519 2. The German Medicine of Johann Vochs: Medical and Cultural Reform on the Eve of the Reformation 3. The Reformation of Healing: Plague, Physicians and Protestantism in the 1520s 4. The Plague Cures of Caspar Kegler: Print, Alchemy and Medical Marketing, 1521-1607 5. The Flourishing of German Medicine, 1530-1580: Humanism, Empiricism, and Protestantism Conclusion Appendix 1: Publication History of Caspar Kegler's Pamphlets Appendix 2: Vernacular Plague Texts 1473-1607 in Chronological Order.
  • (source: Nielsen Book Data)9781472473141 20171204
This book surveys a neglected set of sources, German plague prints and treatises published between 1473 and 1573, in order to explore the intertwined histories of plague, print, medicine and religion during the Reformation era. It argues that a particularly German reform of healing flourished in printed texts during the Renaissance and Reformation as physicians and clerics devised innovative responses to the era's persistent epidemics. These reforms are "German" since they reflect the innovative trends that originated in or were particularly strong within German-speaking lands, including the rapid growth of vernacular print, Protestantism, and new interest in alchemy and the native plants of Northern Europe that were unknown to the ancients. Their reforms are also "German" in the sense that they unfolded mainly in vernacular print, which encouraged physicians to produce local knowledge, grounded in personal experience and local observations as much as universal theories. This book contributes to the history of medicine and science by tracing the growth of more empirical forms of medical knowledge. It also contributes to the history of the Renaissance and Reformation by uncovering the innovative contributions of various forgotten physicians. This book presents the broadest study of German plague treatises in any language.
(source: Nielsen Book Data)9781472473141 20171204
Green Library
1 online resource : color illustrations
  • SECTION I: BASIC CONCEPTS IN LIVER PATHOLOGY 1 Microscopic Anatomy, Basic Terms, and Elemental Lesions SECTION II: CLINICAL, LABORATORY, AND RADIOLOGIC FEATURES OF LIVER DISEASE 2 Clinical Features of Liver Disease 3 Laboratory Tests in Liver Disease 4 Investigative Imaging of the Liver SECTION III: LIVER DISEASES OF CHILDHOOD 5 Liver Diseases of Childhood SECTION IV: METABOLIC DISEASES OF THE LIVER 6 Medical Genetics and Biochemistry in Diagnosis and Management 7 Histologic Patterns of Metabolic Liver Diseases 8 Liver in Wilson Disease 9 Liver Disease in Alpha-1 Antitrypsin Deficiency 10 Liver Disease in Cystic Fibrosis 11 Liver Disease in Iron Overload 12 Nonalcoholic Fatty Liver Disease SECTION V: INFECTIOUS DISEASES OF THE LIVER 13 Acute Viral Hepatitis 14 Hepatitis B 15 Hepatitis C 16 Chronic Hepatitis: Grading and Staging 17 Human Immunodeficiency Virus Infection of the Liver 18 Nonviral Infections of the Liver SECTION VI: GRANULOMATOUS DISEASES OF THE LIVER 19 Hepatic Granulomas: Differential Diagnosis 20 Hepatic Sarcoidosis SECTION VII: AUTOIMMUNE HEPATITIS 21 Autoimmune Hepatitis and Overlap Syndromes SECTION VIII: DRUG- AND TOXIN-INDUCED LIVER INJURY 22 Metabolism of Drugs and Xenobiotics 23 Liver Injury Due to Drugs and Herbal Agents 24 Alcohol-Induced Liver Disease SECTION IX: DISORDERS OF THE BILE DUCTS, BILE FORMATION, AND SECRETION 25 Fibrocystic Liver Diseases 26 Primary Biliary Cholangitis 27 Primary Sclerosing Cholangitis 28 Loss of Intrahepatic Bile Ducts 29A Intrahepatic Cholestasis: Molecular Physiology of Bile Formation and Secretion 29B Intrahepatic Cholestasis: Diseases of Bile Formation and Secretion SECTION X: VASCULAR DISORDERS OF THE LIVER 30 Vascular Disorders of the Liver SECTION XI: TUMORS AND TUMOR-LIKE LESIONS OF THE LIVER 31 Premalignant and Early Malignant Hepatocellular Lesions in Chronic Hepatitis/Cirrhosis 32 Benign Hepatocellular Tumors 33 Hepatocellular Carcinoma 34 Benign and Malignant Tumors of Bile Ducts 35 Liver Tumors of Childhood 36 Miscellaneous Liver Tumors and Tumor-like Lesions SECTION XII: LIVER TRANSPLANTATION 37 Clinical Aspects of Liver Transplantation 38 Pathology of Liver Transplantation SECTION XIII: EVOLVING CONCEPTS IN LIVER PATHOLOGY 39 Biphenotypic Primary Liver Carcinoma 40 Regression of Liver Fibrosis: From Myth to Reality 41 Cirrhosis: A Term in Need of a Makeover.
  • (source: Nielsen Book Data)9780323428736 20171204
A volume in the popular Pattern Recognition Series, Practical Hepatic Pathology: A Diagnostic Approach features completely updated and reorganized content, resulting in a truly practical guide to understanding liver pathology. Dr. Romil Saxena presents interpretation of liver biopsies according to a pattern-based approach that begins with recognition of the predominant histological pattern of injury, followed by identification of secondary features and appropriate work-up that lead you away from pitfalls to the best diagnosis. Unique "visual index" at the beginning of the book references the exact chapter and specific page needed for in-depth diagnostic guidance. Superb, high-quality, full-color images illustrate pathognomonic features and common variations. Features comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules, including clinical features, laboratory tests, imaging findings and differential diagnosis. Coverage of the clinical aspects of liver transplantation allows you to understand the pathology and practice of this procedure. Virtual Microscope provides your own personal set of over 300 liver slides accessible anywhere, any time on your favorite digital device. Navigate around and zoom in and out to savor these exceptionally high quality whole slide images covering everything from the normal liver to rare challenging cases. New section on Evolving Concepts keeps you abreast of new paradigms in liver diseases such as reversal of fibrosis, heterogeneity of cirrhosis, and biphenotypic primary liver cell carcinoma. Reorganized Table of Contents is even more intuitive. Expert Consult eBook version is included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book across digital platforms.
(source: Nielsen Book Data)9780323428736 20171204
1 online resource.
  • 1. A Healthy Diet for Your Heart and Your Brain 2. Dietary Patterns 3. Epidemiological and Nutritional Methods 4. Not All Fats are Unhealthy 5. Virgin Olive Oil: A Mediterranean Diet Essential 6. A Small Handful of Mixed Nuts 7. Fruits and Vegetables 8. Cereals and Legumes: Provides a High Quality Source of Proteins and Fiber 9. More Fish, Less Meat 10. Red Wine Moderate Consumption and at Mealtimes 11. The Mediterranean Life Style: Not Only Diet But Also Socializing and Physical Activity 12. The Mediterranean Cook: Recipes for All Seasons.
  • (source: Nielsen Book Data)9780128112595 20171017
The Prevention of Cardiovascular Disease through the Mediterranean Diet presents dietary habits that will have maximum impact on cardiovascular health and other major chronic diseases. Data collected through the results of large clinical trials, such as PREDIMED, one of the longest trials ever conducted, has allowed researchers to conclude that the Mediterranean Diet provides the best evidence for health benefits. Studies have shown that the Mediterranean Diet is able to reduce the risk of cardiovascular hard clinical events by 30%. This book explores the components of this diet, including the consumption of extra virgin olive oil, nuts, fresh fruits and vegetables, fatty fish, poultry and red wine for optimal health benefits.
(source: Nielsen Book Data)9780128112595 20171017

26. Pulmonary pathology [2018]

1 online resource (xiv, 759 pages) : color illustrations
  • 1. Normal Anatomy, Tissue Artifacts, and Incidental Structures 2. The Uses and Abuses of the Lung Biopsy 3. A Pattern-Based Approach to Diagnosis 4. Congenital, Developmental, and Inherited Disorders 5. Acquired and Idiopathic Disorders in Neonates and Young Children 6. Lung Neoplasms in Infants and Children 7. Vascular Diseases 8. Vasculitides and Other Causes of Pulmonary Hemorrhage 9. Acute Lung Injury 10. Bacterial Diseases 11. Mycobacterial Diseases 12. Fungal Diseases 13. Viral Diseases 14 Human Parasitic Pulmonary Infections 15 Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases 16. Idiopathic Interstitial Pneumonias 17. Other Interstitial Lung Diseases 18. Environmental- and Toxin-Induced Lung Diseases 19. Drug Reactions and Other Iatrogenic Pulmonary Diseases 20. Emphysema and Diseases of Large Airways 21. Diseases of Small Airways 22. Lymphoid Lesions of the Lung 23. Uncommon Histiocytic and Dendritic Cell Proliferations 24. Transplantation-Related Lung Pathology 25. Other Non-Neoplastic Focal Lesions, Inclusions, and Depositions.
  • (source: Nielsen Book Data)9780323393089 20170410
Now fully revised to include recent advances in the field, the second edition of Pulmonary Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what's new in pulmonary pathology and pulmonary medicine, including molecular genetics and personalized medicine therapies. Practical and affordable, this resource by Drs. Dani S. Zander and Carol F. Farver is ideal for study and review as well as everyday clinical practice.
(source: Nielsen Book Data)9780323393089 20170410
1 online resource (xv, 219 pages) : illustrations (some color).
  • Title Page; Copyright; Dedication; Table of Contents; List of Contributors; Acknowledgements; Introduction; Chapter 1: Subtotal Nephrectomy and Tumour Ablation; Introduction; Procedures; Conclusions; References; Chapter 2: Renal Transplantation; Introduction; The Role of Ultrasound Imaging; Vascular Complications; Urological Complications; Conclusions; References; Chapter 3: Imaging After Endo-urological Stone Treatment; Introduction; The Procedures; Ureteric Stones: Results and Complications; Renal Stones: Results and Complications; Complications and Follow-up; References
  • Chapter 4: Pelvi-ureteric Junction ReconstructionIntroduction; Antenatal Hydronephrosis; Pathophysiological Effect of True Pelvi-ureteric Obstruction; Physiological and Anatomical Changes in the Kidney Following Pyeloplasty; Incidental PUJO in adults; Long-term Follow-up; Conclusions; References; Chapter 5: Retroperitoneal Fibrosis; Introduction; Available Treatments; Follow-up; Complications; Long-term Follow-up; References; Chapter 6: Urinary Diversion; Introduction; The Procedures; Postoperative Imaging; Monitoring of Asymptomatic Patients; Management of Bacteriuria and Sepsis; References
  • Chapter 7: Ureteric Reconstruction and ReplacementIntroduction; Procedures; Clinical Follow-up and Complications; References; Chapter 8: Conservative and Reconstructive Bladder Surgery; Introduction; Extravasation; Bladder Perforation; Reconstruction Following Ureteric Injury and Partial Cystectomy; The Irradiated Bladder; Complications After Posterior Exenteration; Conclusions; References; Chapter 9: Bladder Augmentation in Children; Introduction; The Procedures; Clinical Follow-up; Postoperative Imaging; Complications of Enterocystoplasty; Unique Complications of Gastrocystoplasty
  • Changes Over TimeReferences; Chapter 10: Radiology and Follow-up of the Neobladder; Introduction; The Procedure; The Neobladder; Postoperative Imaging; Clinical Follow-up; Oncologic Follow-up Specific to the Neobladder; Secondary Tumour Growth in Urinary Diversions for Benign Disease (see also Chapter 11); Complications; Changes Over Time; References; Chapter 11: General Consequences of Lower Urinary Tract Replacement and Reconstruction; Introduction; Reservoirs; Urodynamic Findings; Stones; Renal Function; Perforation; Histological Changes; Infection; Neoplasia; Urine Testing for Pregnancy
  • The Conduit and ContinenceReferences; Chapter 12: Surgery on the Benign Prostate; Introduction; Procedures; Outcomes and Complications; Changes Over Time; References; Chapter 13: Imaging After Treatment of Prostate Cancer; Introduction; Appearances After Radical Prostatectomy; Residual Tumour After Radical Prostatectomy; The Prostate After Ablative Therapies; References; Chapter 14: Urethroplasty; Introduction; Pericatheter Urethrogram; Ascending and Descending Urethrography; References; Chapter 15: The Postoperative Appearance and Follow-up of Urinary Tract Prostheses; Introduction
13 PDFs (ix, 136 pages)
  • Chapter 1. Introduction: mental health and well-being of college students
  • Chapter 2. Mental health and well-being: societal influences
  • Chapter 3. Dispositional factors influencing college success: personality, character, and mindset
  • Chapter 4. Strategies for the college classroom
  • Chapter 5. Campus-wide initiatives
  • Chapter 6. What is next?: future considerations.
The state of college students' mental health is a growing phenomenon across university campuses. Educators often watch students struggle with academic, social, financial, and familial issues. Over the past decade, these issues have led to an increasing number of students exhibiting behavior related to anxiety, depression, and other mental health disorders.Raising Mental Health Awareness in Higher Education: Emerging Research and Opportunities describes the current state of college students' mental health in the United States, influences that contribute to wavering mental health, factors that promote flourishing mental health, and interventions that support mental health. While highlighting present programs and activities, readers will find new methods that can be implemented to support the needs of college students. This book is an important resource for staff and faculty in postsecondary institutions seeking current research on the growing problem of mental health in higher education.
(source: Nielsen Book Data)9781522537939 20171211
1 online resource.
  • ""Front Cover""; ""Cancer Sensitizing Agents for Chemotherapy: Role of Nutraceuticals in Cancer Chemosensitization""; ""Copyright""; ""Contents""; ""Contributors""; ""About the Editors""; ""About the Series Editor""; ""Aims and Scope for Series â#x80; #x9C; Cancer Sensitizing Agents for Chemotherapyâ#x80; #x9D; ""; ""Preface""; ""Chapter 1: Pathways Linked to Cancer Chemoresistance and Their Targeting by Nutraceuticals""; ""Introduction""; ""Chemotherapy""; ""Alkylating Agents""; ""Cell Cycle Inhibitors/Antimicrotubule Agents""; ""Antimetabolites""; ""Antibiotics""; ""Topoisomerase Inhibitors""
  • ""Targeted Therapy""""Target-Specific Antibodies""; ""Small Molecule Inhibitors""; ""Chemoresistance: Problem in Curing Cancer""; ""Mechanism of Chemoresistance""; ""Drug Transporters""; ""Enhanced DNA Repair System""; ""Drug Inactivation""; ""Altered Drug Targets""; ""Epithelial-Mesenchymal Transition""; ""Inhibition of Apoptosis""; ""Autophagy""; ""Aberrant Expression and Constitutive Activation of Transcription Factors""; ""Nuclear Factor-Kappa B (NF-κB)""; ""Signal Transducers and Activators of Transcription 3 (STAT-3)""; ""Activating Protein-1 (AP-1)""
  • ""Activation of Self-Renewal Pathways""""Chemosensitization: An Approach to Target Cancer""; ""Nutraceuticals as Chemosensitizers: Opportunities and Challenges""; ""Conclusion""; ""Conflict of Interest""; ""Acknowledgments""; ""References""; ""Chapter 2: The Potential of Curcumin: A Multitargeting Agent in Cancer Cell Chemosensitization""; ""Introduction""; ""Molecular Targets of Curcumin""; ""Chemosensitization Studies of Curcumin in Different Cancers""; ""Curcumin Mediated Chemosensitization in Bladder Cancer""; ""Curcumin Mediated Chemosensitization in Brain Cancer""
  • ""Curcumin Mediated Chemosensitization in Breast Cancer""""Curcumin Mediated Chemosensitization in Cervical Cancer""; ""Curcumin Mediated Chemosensitization in Colon Cancer""; ""Curcumin Mediated Chemosensitization in Esophageal Cancer""; ""Curcumin Mediated Chemosensitization in Leukemia""; ""Curcumin Mediated Chemosensitization in Lung Cancer""; ""Curcumin Mediated Chemosensitization in Multiple Myeloma""; ""Curcumin Mediated Chemosensitization in Ovarian Cancer""; ""Curcumin Mediated Chemosensitization in Pancreatic Cancer""; ""Curcumin Mediated Chemosensitization in Prostate Cancer""
  • ""Curcumin Mediated Chemosensitization in Other Cancers""""Hybrid Curcumin""; ""Conclusion""; ""Conflict of Interest""; ""Acknowledgment""; ""References""; ""Further Reading""; ""Chapter 3: Role of Resveratrol in Chemosensitization of Cancer""; ""Introduction""; ""Source and Chemistry of Resveratrol""; ""Possible Molecular Mechanisms of Chemoresistance in Cancer""; ""ATP-Dependent Drug Efflux""; ""Drug Detoxification""; ""Alterations in Drug Target Molecules""; ""Alterations in DNA Damage Repair Pathways""; ""Regulation of Cell Cycle Arrest""; ""Regulation of Apoptosis""
Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use nutraceuticals as a sensitizing agent for chemotherapy.
1 online resource (384 pages)
  • (source: Nielsen Book Data)9780323480420 20170911
A highly clinical focus and clear, vibrant illustrations make Textbook of Clinical Hemodynamics, 2nd Edition, by Dr. Michael Ragosta, the resource of choice for accurately analyzing hemodynamic waveforms generated in cardiac catheterization labs. This easy-to-use, disease-oriented reference-ideal for physicians, nurses, and technicians-offers the unparalleled detail and visual support you need for interpreting the findings you encounter in practice. New coverage throughout keeps everyone on the cardiac team up to date with the latest concepts and skills, ensuring more effective monitoring and treatment of patients with cardiac disease.
(source: Nielsen Book Data)9780323480420 20170911
1 online resource (xiv, 362 pages) : illustrations (some color). Digital: text file; PDF.
  • Analysis of chromosomal alterations in urothelial carcinoma / Donatella Conconi and Angela Bentivegna
  • Analysis of point mutations in clinical samples of urothelial carcinoma / Mustafa Alamyar and Ellen C. Zwarthoff
  • Versatile assay for detection of aberrant DNA methylation in bladder Cancer / Stella Tommasi and Ahmad Besaratinia
  • Immunohistochemical analysis of urothelial carcinoma tissues for proliferation and differentiation markers / Michael Rose and Nadine T. Gaisa
  • Molecular subtype profiling of urothelial carcinoma using a subtype-specific immunohistochemistry panel / Gottfrid Sjodahl
  • Defining the pathways of urogenital schistosomiasis-sssociated urothelial carcinogenesis through transgenic and bladder wall egg injection models / Evaristus C. Mbanefo and Michael H. Hsieh
  • Algorithm for the automated evaluation of NAT2 genotypes / Georg Michael, Ricarda Thier, Meinolf Blaszkewicz, Silvia Selinski, and Klaus Golka
  • Detection of APOBEC3 proteins and catalytic activity in urothelial carcinoma / Ananda Ayyappan Jaguva Vasudevan, Wolfgang Goering, Dieter Haussinger, and Carsten Munk
  • Oxidative stress in urothelial carcinogenesis : measurements of protein carbonylation and intracellular production of reactive oxygen species / Patcharawalai Whongsiri, Suchittra Phoyen, and Chanchai Boonla
  • Urothelial carcinoma stem cells : current concepts, controversies, and methods / Jiri Hatina, Hamendra Singh Parmar, Michaela Kripnerova, Anastasia Hepburn, and Rakesh Heer
  • In vitro differentiation and propagation of urothelium from pluripotent stem cell lines / Stephanie L. Osborn and Eric A. Kurzrock
  • Spheroid cultures of primary urothelial cancer cells : cancer tissue-originated spheroid (CTOS) method / Takahiro Yoshida, Hiroaki Okuyama, Hiroko Endo, and Masahiro Inoue
  • N-butyl-N-4-hydroxybutyl nitrosamine mouse urinary bladder cancer model / Paula A. Oliveira, Carmen Vasconcelos-Nobrega, Rui M. Gil da Costa, and Regina Arantes-Rodrigues
  • Patient-derived bladder cancer xenografts / Carina Bernardo and Lucio Lara Santos
  • Orthotopic mouse models of urothelial cancer / Wolfgang Jager, Igor Moskalev, Peter Raven, Akihiro Goriki, Samir Bidnur, and Peter C. Black
  • Quantification of microRNAs in urine-derived specimens / Susanne Fuessel, Andrea Lohse-Fischer, Dana Vu Van, Karsten Salomo, Kati Erdmann, and Manfred P. Wirth
  • Quantitative RNA analysis from urine using real time PCR / Lourdes Mengual and Mireia Olivan
  • DNA methylation analysis from body fluids / Dimo Dietrich
  • Urinary protein markers for the detection and prognostication of urothelial carcinoma / Tibor Szarvas, Peter Nyirady, Takashi Kobayashi, Osamu Ogawa, Charles J. Rosser, and Hideki Furuya
  • Isolation and characterization of CTCs from patients with cancer of a urothelial origin / Vladimir Bobek and Katarina Kolostova.
This volume details standard techniques for the characterization of urothelial carcinoma as well as methods to investigate mechanisms of carcinogenesis. Chapters guide readers on cellular and animal models for urothelial carcinoma and related diseases, molecular analyses from body fluids, and new approaches to therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Urothelial Carcinoma: Methods and Protocols hopes that the techniques described in this volume will contribute to the current upturn in research on urothelial carcinoma and to the application of its results in clinical practice.
(source: Nielsen Book Data)9781493972333 20171201
150 pages : illustrations ; 23 cm
  • Vorwort
  • Wichtige Abkürzungen
  • James Parkinson
  • Beschreibungen aus der Zeit vor James Parkinson
  • Der grosse Verdienst von James Parkinson
  • An Essay on the Shaking Palsy unter der Lupe
  • Das Leben von James Parkinson (1755-1824)
  • Jean-Martin Charcot
  • Die ersten Jahrzehnte nach Parkinsons Publikation
  • Charcots Beiträge
  • Das Leben von Jean-Martin Charcot (1825-1893)
  • Der Durchbruch lässt auf sich warten
  • Die erfolgreiche Suche nach einer Pathologie
  • Postenzephalitisches Parkinsonsyndrom
  • Untersuchungen zum Rigor
  • Das lange Warten auf eine wirksame Behandlung
  • Die Einführung von L-Dopa : ein therapeutischer Durchbruch
  • L-Dopa und Dopamin
  • Die ersten Therapieversuche am Patienten
  • Die Einführung in die Klinik
  • L-Dopa plus Dekarboxylasehemmer wird zum Goldstandard
  • COMT-Hemmer
  • Intestinale (jejunale) Infusion von L-Dopa plus Carbidopa
  • Andere wichtige Medikamente
  • Anticholinergika
  • Dopaminagonisten
  • Amantadin
  • MAO-B-Hemmer
  • Probleme der Langzeitbehandlung
  • Motorische Komplikationen
  • Psychische Komplikationen
  • Neurotoxizität und Neuroprotektion
  • Neurotoxine
  • Ist L-Dopa neurotoxisch?
  • Neuroprotektion
  • Hat die dopaminerge Behandlung die Lebenserwartung der Patienten verändert?
  • Renaissance der chirurgischen Behandlung
  • Tiefe Hirnstimulation (THS)
  • Zelltherapien
  • Neue Einsichten in das Krankheitsbild
  • Die Definitionen der Symptomatik ändern sich
  • Atypische Parkinsonsyndrome
  • Steht ein weiterer Durchbruch bevor?
  • Die Rolle von ... -Synuklein
  • Die Braak-Stadien
  • Entsteht das Krankheitsgeschehen im Magen-Darmtrakt?
  • Glossar
  • Literatur
  • Schlagwort- und Namenverzeichnis
  • Quellennachweis.
SAL3 (off-campus storage)
xxvi, 491 pages : illustrations ; 26 cm
  • (source: Nielsen Book Data)9780198727224 20161213
The central problem in the study of addiction is to explain why people repeatedly behave in ways they know are bad for them. For much of the previous century and until the present day, the majority of scientific and medical attempts to solve this problem were couched in terms of involuntary behavior; if people behave in ways they do not want, then this must be because the behavior is beyond their control and outside the realm of choice. An opposing tradition, which finds current support among scientists and scholars as well as members of the general public, is that so-called addictive behavior reflects an ordinary choice just like any other and that the concept of addiction is a myth. The editors and authors of this book tend to take neither view. There has been an increasing recognition in recent literature on addiction that restricting possible conceptions of it to either of these extreme positions is unhelpful and is retarding progress on understanding the nature of addiction and what could be done about it. This book contains a range of views from philosophy, neuroscience, psychiatry, psychology and the law on what exactly this middle ground between free choice and no choice consists of and what its implications are for theory, practice and policy on addiction. The result amounts to a profound change in our thinking on addiction and how its devastating consequences can be ameliorated. Addiction and Choice is a thought provoking new volume for all those with an interest in this global issue.
(source: Nielsen Book Data)9780198727224 20161213
Green Library
viii, 271 pages : illustrations (some color), charts ; 25 cm
  • Combining radiotherapy and immunotherapy
  • SBRT and the treatment of oligometastatic disease
  • MRI guided radiotherapy
  • Oncologic applications of magnetic resonance guided focused ultrasound
  • Intensity-modulated proton beam therapy of prostate cancer- history, results, and future directions
  • IGRT and hypofractionation for primary tumors
  • The impact of IGRT on normal tissue toxicity
  • Biologic and image guided systemic radiotherapy
  • Cancer stem cells and tumor microenvironment in radiotherapy
  • Biomarkers and radiotherapy
  • The mammalian DNA damage response as a target for therapeutic gain in radiation oncology
  • Mathematical modeling in radiation oncology.
Medical Library (Lane)
1 online resource.
  • Part I: General Aspects 1. Introduction 2. Protein and Lipid Kinases 3. Kinase Inhibitors 4. Adverse Events Part II: Oncotargeted Kinase Inhibitors 5. Imatinib 6. Gefitinib 7. Erlotinib 8. Sorafenib 9. Sunitinib 10. Dasatinib 11. Lapatinib 12. Nilotinib 13. Pazopanib 14. Vandetanib 15. Vemurafenib 16. Crizotinib 17. Ruxolitinib 18. Axitinib 19. Bosutinib 20. Regorafenib 21. Cabozantinib 22. Ponatinib 23. Dabrafenib 24. Trametinib 25. Adatinib 26. Idelalisib 27. Ibrutinib Part III: Overview 28. Kinase Inhibitors as Adverse Event Inducers 29. Kinase Inhibitors as Drug Class Events 30. Conclusion and Perspectives.
  • (source: Nielsen Book Data)9780128094006 20170612
Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug's development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement. This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events.
(source: Nielsen Book Data)9780128094006 20170612
1 online resource
1 online resource
  • Sample Proportions and the Normal Distribution. Developing Competence in Working With LGBTQI+ Communities: Awareness, Knowledge, Skills, and Action / Misty M Ginicola, Cheri Smith, Joel M Filmore
  • The Science of Gender and Affectional Orientation / Misty M Ginicola
  • Growing Up LGBTQI+: The Importance of Developmental Conceptualizations / Anneliese A Singh, Kristopher M Goodrich, Amney J Harper, Melissa Luke
  • LGBTQI+ Youth Development / Melissa Luke, Amney J Harper, Kristopher M Goodrich, Anneliese A Singh
  • LGBTQI+ Persons in Adulthood / Amy Moore-Ramirez, Melanie Kautzman-East, Misty M Ginicola
  • Identity Development, Coming Out, and Family Adjustment / Kristopher M Goodrich, Misty M Ginicola
  • Physical and Mental Health Challenges Found in the LGBTQI+ Population / Misty M Ginicola, Joel M Filmore, Cheri Smith, Jahaan Abdullah
  • Disaffirming Therapy: The Ascent and Descent of Sexual Orientation Change Efforts / Peter Finnerty, Michael M Kocet, Jeff Lutes, Chad Yates
  • Evidence-Based Practice for Counseling the LGBTQI+ Population / Kristopher M Goodrich, Misty M Ginicola
  • Affirmative, Strengths-Based Counseling With LGBTQI+ People / Peter Finnerty, Michael M Kocet, Jeff Lutes, Chad Yates
  • Counseling Lesbian Clients / Cindy Anderton, Lindsay Woodbridge
  • Counseling Gay Male Clients / Misty M Ginicola, Samuel Sanabria, Joel M Filmore, Michael DeVoll
  • Counseling Bisexual/Pansexual/Polysexual Clients / Amney J Harper, Misty M Ginicola
  • Counseling Transgender Clients / Robyn Brammer, Misty M Ginicola
  • Counseling Queer and Genderqueer Clients / Jeffry Moe, Jamie Bower, Madeline Clark
  • Counseling Clients Questioning Their Affectional Orientation / Jared S Rose, Eric R Baltrinic
  • Counseling Intersex Clients / Misty M Ginicola
  • Sample Means and the Normal Distribution. Counseling Asexual Clients / Misty M Ginicola, Angela Ruggiero
  • Counseling Two-Spirit Clients / Misty M Ginicola
  • Counseling an LGBTQI+ Person of Color / Joel M Filmore, Misty M Ginicola
  • Counseling LGBTQI+ Immigrants / David Barreto, Amy Moore-Ramirez, Melanie Kautzman-East, Ryan Liberati
  • The Role of Religion and Spirituality in Counseling the LGBTQI+ Client / Misty M Ginicola, Brett H Furth, Cheri Smith
  • The GRACE Model of Counseling: Navigating Intersections of Affectional Orientation and Christian Spirituality / R Lewis Bozard, Cody J Sanders
  • Working With LGBTQI+ Clients Who Have Experienced Religious and Spiritual Abuse Using a Trauma-Informed Approach / Misty M Ginicola, Joel M Filmore, Michael Stokes
  • Becoming an Ally: Personal, Clinical, and School-Based Social Justice Interventions / Diane Estrada, Anneliese A Singh, Amney J Harper.
xv, 274 pages ; 26 cm.
  • Gender and sexual orientation diversity within the TGNC community / Sand C. Chang, Anneliese A. Singh, and Kinton Rossman
  • Affirmative counseling with trans/gender-variant people of color / Anneliese A. Singh, Sel J. Hwahng, Sand C. Chang, and Bali White
  • TGNC-affirmative interdisciplinary collaborative care / Kelly Ducheny, Michael L. Hendricks, and Colton L. Keo-Meier
  • Ethical and legal concerns for mental health professionals / Linda F. Campbell and Gabriel Arkles
  • Affirmative care of TGNC children and adolescents / Laura Edwards-Leeper
  • Working with TGNC primary caregivers and family concerns across the lifespan / Sand C. Chang, Jessie R. Cohen, and Anneliese A. Singh
  • Aging and TGNC identities : working with older adults / lore m. dickey and Kyle L. Bower
  • Clinical supervision with TGNC clients in health service psychology / Theodore R. Burnes, Stacie Fishell Rowan, and Parrish L. Paul
  • Assessment and treatment of trauma with TGNC clients : a feminist approach / Katherine Richmond, Theodore R. Burnes, Anneliese A. Singh, and Mel Ferrara
  • Spirituality, faith, and religion : the TGNC experience / Ruben A. Hopwood and Tarynn M. Witten
  • Engaging in TGNC-affirmative research / Jae Sevelius, lore m. dickey, and Anneliese A. Singh
  • Advocacy and social justice : the next generation of counseling and psychological practice with transgender and gender-nonconforming clients / lore m. dickey, Anneliese A. Singh, Sand C. Chang, and Mich Rehrig.
Less than 30% of psychologists report familiarity with transgender and gender nonconforming (TGNC) clients' needs. The clients, in turn, report a lack of support in their gender journeys. There is clearly a large gap in knowledge, skill, and competence in this area of practice. This clinical guide fills that gap by providing mental health practitioners with an affirmative approach that emphasises a collaborative partnership guided by client-driven goals. An expert panel of contributors teaches readers strategies for working with a diverse array of TGNC clients, including adolescents, older adults, parents, and people of colour. Client factors, including sexual orientation, religious and spiritual beliefs, and traumatic experiences, are also given special attention. Readers will learn how to address the impact of the injustices TGNC people face in everyday life, work with clients' strengths to enhance their resilience and coping skills, and advocate for their rights to obtain mental and physical health services. They will also learn how to negotiate complex issues, such as interdisciplinary care, ethical and legal obligations, and gender-affirming surgeries and medications. The chapter authors draw from evidence-based theories and APA's "Guidelines for Psychological Practice With Transgender and Gender Nonconforming People (PDF, 462KB)" to help readers meet the latest standards of care.
(source: Nielsen Book Data)9781433823008 20161108
Green Library
1 online resource (xiii, 278 pages) : illustrations (some color) Digital: text file; PDF.
  • Pathophysiology of alpha-1 antitrypsin deficiency liver disease / Jeffrey H. Teckman and Keith S. Blomenkamp
  • Pathophysiology of alpha-1 antitrypsin lung disease / Michael Kalfopoulos, Kaitlyn Wetmore, and Mai K. ElMallah
  • Measuring and interpreting serum AAT concentration / Leslie J. Donato, Melissa R. Snyder, and Dina N. Greene
  • AAT phenotype identification by isoelectric focusing / Dina N. Greene, M.C. Elliott-Jelf, and David G. Grenache
  • Laboratory diagnosis by genotyping / Irene Belmonte, Luciana Montoto, and Francisco Rodrıguez-Frıas
  • Genotyping protocol for the alpha-1 antitrypsin (PiZ) mouse model / Alisha M. Gruntman
  • Elastase-induced lung emphysema models in mice / Bela Suki, Erzsebet Bartolak-Suki, and Patricia R.M. Rocco
  • Assessing structure-function relations in mice using the forced oscillation technique and quantitative histology / Harikrishnan Parameswaran and Bela Suki
  • Practical methods for assessing emphysema severity based on estimation of linear mean intercept (Lm) in the context of animal models of alpha-1 antitrypsin deficiency / Airiel M. Davis, Kristen E. Thane, and Andrew M. Hoffman
  • Design, cloning, and in vitro screening of artificial miRNAs to silence alpha-1 antitrypsin / Florie Borel and Christian Mueller
  • Methods to identify and characterize siRNAs targeting serpin A1 in vitro and in vivo using RNA interference / Stuart Milstein, Kun Qian, Linying Zhang, and Alfica Sehgal
  • Knockdown of Z mutant alpha-1 antitrypsin in vivo using modified DNA antisense oligonucleotides / Mariam Aghajan, Shuling Guo, and Brett P. Monia
  • Immunohistochemistry staining for human alpha-1 antitrypsin / Dongtao A. Fu and Martha Campbell-Thompson-- Periodic acid-schiff staining with diastase / Dongtao A. Fu and Martha Campbell-Thompson
  • Protocol for directed differentiation of human induced pluripotent stem cells (iPSCs) to a hepatic lineage / Joseph E. Kaserman and Andrew A. Wilson
  • Isolation of kupffer cells and hepatocytes from a single mouse liver / Marcela Aparicio-Vergara, Michaela Tencerova, Cecilia Morgantini, Emelie Barreby, and Myriam Aouadi
  • Alpha-1 antitrypsin transcytosis and secretion / Angelia D. Lockett
  • Measuring the effect of histone deacetylase inhibitors (HDACi) on the secretion and activity of alpha-1 antitrypsin / Chao Wang, Marion Bouchecareilh, and William E. Balch
  • Expression and purification of active recombinant human Alpha-1 antitrypsin (AAT) from Escherichia coli / Beena Krishnan, Lizbeth Hedstrom, Daniel N. Hebert, Lila M. Gierasch, and Anne Gershenson
  • Quantification of total human alpha-1 antitrypsin by sandwich ELISA / Qiushi Tang, Alisha M. Gruntman, and Terence R. Flotte
  • Quantification of murine AAT by direct ELISA / Andrew Cox and Christian Mueller
  • Quantification of Z-AAT by a Z-specific "sandwich" ELISA / Florie Borel, Qiushi Tang, and Christian Mueller
  • Semiquantitation of monomer and polymer alpha-1 antitrypsin by centrifugal separation and assay by western blot of soluble and insoluble components / Keith S. Blomenkamp and Jeffrey H. Teckman
  • Electrophoresis- and FRET-based measures of serpin polymerization / Sarah V. Faull, Anwen E. Brown, Imran Haq, and James A. Irving
  • Therapeutics : alpha-1 antitrypsin augmentation therapy / Michael Campos and Jorge Lascano
  • Therapeutic options in alpha-1 antitrypsin deficiency : liver transplantation / Nedim Hadzic
  • Therapeutics : gene therapy for alpha-1 antitrypsin deficiency / Alisha M. Gruntman and Terence R. Flotte.
This volume provides protocols that expand on the latest alpha-1-antitrypsin (AAT) research. The chapters in this book are divided in to three sections: Part I is dedicated to patient-oriented research; part II discusses animal models; and Part III focuses on in vitro studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Alpha-1 Antitrypsin Deficiency: Methods and Protocols is a valuable resource for researchers, students, and clinican-scientists interested in AAT deficiency, as well as anyone working in the fields of pulmonology and hepatology.
(source: Nielsen Book Data)9781493971619 20171009
1 online resource.
  • Cover ; Title page; Copyright page; Contents; List of Contributors; Preface; Acknowledgments; Chapter 1
  • Historical Perspective; Introduction; The discovery of alpha-1-antitrypsin deficiency (AATD); AATD and association with pulmonary emphysema; AATD and association with liver disease; Other disease associations; References; Further Reading; Chapter 2
  • The Swedish Alpha-1-Antitrypsin Screening Study: What We Have Learnt From Birth to Adult Life; Introduction; Fetal life; The liver; Infancy and Childhood; Adolescence and Young Adulthood; The Lungs; Smoking; Adaptive Biochemical Changes
  • Psychological Effects of the Neonatal Alpha-1-Antitrypsin ScreeningFinal Speculation; References; Chapter 3
  • Alpha-1-Antitrypsin Gene Regulation; Introduction; AAT, acute-phase, and tissue expression; The Serpin cluster on 14q31-31.2, the AAT gene, and transcripts; AAT hepatocyte promoter and enhancers; Control of AAT expression in nonhepatic tissue; AAT locus control region and interaction with transcription factors; References; Chapter 4
  • Alpha-1-Antitrypsin Variants; Introduction; Alpha-1-antitrypsin nomenclature and isoelectric focusing; Noncoding DNA variants; References
  • Further ReadingChapter 5
  • Alpha1-Antitrypsin: Structure and Dynamics in Health, Disease and Drug Development; Introduction; Why Understanding the Conformational Behavior of Alpha1-Antitrypsin Matters in Alpha1-Antitrypsin Deficiency; Conformational states associated with function and dysfunction; The Native Conformation; Complexed With Protease as a Consequence of the Functional Mechanism; How Structure Determines Function; The Cleaved Conformation; Finding of Polymers in Disease; Importance of dynamics; Dynamics of Native Wild-Type Alpha1-Antitrypsin in Solution
  • Alpha1-Antitrypsin Folding: How Does It Go Right, How Does It Go Wrong?How Does Alpha1-Antitrypsin Avoid Folding to the Inactive Latent Conformation?; Intracellular Misfolding and Polymerization of Alpha1-Antitrypsin; In vitro studies of Alpha1-Antitrypsin polymerization: lessons and limitations; Different Alpha1-Antitrypsin Polymers Form in Different Experimental Conditions; Studies of M*: the Polymerogenic Intermediate State; Disulfide Locking of Intracellular Polymers; Other Polymeric Architectures Observed In Vitro; Translation; Relating Deficiency Mutations to Disease Phenotype
  • Translating to New Therapeutic Strategies: Stabilizing Alpha1-Antitrypsin Against Pathological Conformational ChangeS4A Blockade; Allosteric stabilization; Polymerization Blockade by a Monoclonal Antibody; Blockade of Disease-Associated Dynamics; Studying polymerization in cells, organisms, and clinical samples; Conclusions; References; Chapter 6
  • Novel Biological Functions of A1AT; Introduction; A1AT is a broad-spectrum inhibitor of proteases; A1AT as an antiinflammatory and immunomodulatory protein; Modified molecular forms of A1AT and their biological functions; S-Nitrosylated A1AT
1 online resource (285 p.) : ill. (some col.).
"The book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a "global" perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world. Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research. Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease. Dr. Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective."--Publisher's website.

42. Stroke [2004]

1 streaming video file (58 min.) : digital, sound, color
Shortly after his marriage to filmmaker Katarina Peters, 33-year-old cellist, Boris Baberkoff suffered a stroke during the couples' wedding trip to New York City. This autobiographical film documents their journey through pain, crisis, guilt, and rehabilitation to recovery.
230 pages : illustrations ; 23 cm
Green Library
1 streaming video file (57 min.) : digital, sound, color
African-Americans die from heart disease at disproportionately higher rates than white Americans, yet many in this community are painfully unaware of the scope of the problem. This film spotlights this modern epidemic through the story of 45-year-old Keith Hartgrove, who has already experienced two heart attacks and quadruple bypass surgery. Together with the experts who are interviewed in this important documentary, he analyzes the impact of a wide variety of factors including depression, stress, diet, smoking and other lifestyle issues, but makes clear that, for African-Americans, such factors are inseparable from racism, and from the discrimination, poverty, segregation, substandard education, and day-to-day tensions which racism engenders.
xviii, 390 pages : illustrations, portrait ; [ca. 23-29] cm
  • 1. Introduction
  • 2. Anti-diabetes mellitus phytochemicals
  • 3. Mechanism of action of anti-diabetes mellitus plants
  • 4. Polyherbal and combination medicines for diabetes mellitus
  • 5. Methods to assess anti-diabetes mellitus activity of plants
  • 6. Sustainable utilization of anti-diabetes mellitus plants.
2 volumes : illustrations ; 29 cm.
  • Volume 1: Foundations in knowledge
  • Volume 2: Trauma practice.
"The two volume 'APA Handbook of Trauma Psychology' is the most comprehensive guide, text, and reference work on the subject to date. It provides a survey of all the major areas and subtopics of empirical knowledge and practical applications in the field of trauma psychology, written by top experts in the field."--The publisher.
Green Library, SAL1&2 (on-campus shelving)
1 online resource : illustrations
  • Chapter 1. Sinus Node - Normal and Abnormal Rhythms Chapter 2. Bradyarrhythmias - Conduction System Abnormalities Chapter 3. Ectopic Complexes and Rhythms Chapter 4. Tachycardia Chapter 5. Supraventricular Tachyarrhythmias Chapter 6. Ventricular Tachyarrhythmias Chapter 7. Cardiac Pacing and Pacemaker Rhythms Chapter 8. Implantable Cardioverter Defibrillators Chapter 9. Drug Effects and Electrolyte Disorders Chapter 10. Athletes and Arrhythmias Chapter 11. Evaluation of the Patient with Suspected Arrhythmias Chapter 12. Treatment of Arrhythmias Chapter 13. Management of Arrhythmias in Pregnancy.
  • (source: Nielsen Book Data)9780323399685 20170410
Concise, compact, fully-illustrated and easy to read, Arrhythmia Essentials, 2nd Edition provides detailed, practical information on recognizing and treating heart rhythm disturbances for clinicians with any level of expertise. The author team, led by renowned authority in cardiac electrophysiology, Dr. Brian Olshansky, guides you skillfully through the different types of arrhythmias and how they present on ECGs. You'll find specific examples of each arrhythmia, numerous algorithms to facilitate an approach to arrhythmia diagnosis and management, updates on medical therapy, and indications for implantable rhythm management devices and ablation - all in a convenient, softcover volume that's perfect for on-the-go reference.
(source: Nielsen Book Data)9780323399685 20170410
xxvii, 216 pages, 6 unnumbered pages of plates : illustrations (some color) ; 24 cm
  • List of Figures Foreword Katherine Williams Preface Paula Howie Acknowledgments About the Contributors Introduction Paula Howie 1. Theoretical Background: Understanding and Treating Soldiers and their Families-Formative Experiences 1. Art Therapy with Military and Veteran Populations: A Historical Context Martha Haeseler and Paula Howie 2. Psychosis, Attachment, and Trauma Paula Howie 3. Inpatient Treatment Charlotte Boston and Jeanne Creekmore 4. Family Art Therapy Treatment at Walter Reed Paula Howie 5. Group Art Therapy: The Evolution of Treatment and the Power of Witness Paula Howie 6. Managing Suicide in the Military Paula Howie 2. Current Trends in Art Therapy Treatment in Military Settings and the Expansion of Treatment Settings 7. Treating the Wounded Warrior: Cognitive and Neural Aspects of Post-Traumatic Stress Disorder Paul Newhouse and Kimberly Albert 8. Complicated Grief: Considerations for Treatment of Military Populations Jacqueline P. Jones 9. Integrative Approaches to Treating PTSD and TBI: Art Therapy Approaches within the National Intrepid Center of Excellence at Walter Reed National Military Medical Center Melissa S. Walker 10. The Giant Steps Program: Creating Fellowship and Meaning Martha Haeseler 11. Art Therapy with Substance Abuse and Co-occurring Disorders in Military Populations Eileen A. McKee 12. Using the Instinctual Trauma Response Model in a Military Setting Linda Gantt and Mary Ellen Vesprini 13. The Sketch Project: Volunteers Giving Veterans a New Perspective Doris Arrington and Nancy Parfitt Hondros 14. Group Therapy and PTSD: Acceptance and Commitment Art Therapy Groups with Vietnam Veterans with PTSD Amy Backos and Corrie Mazzeo 15. Art Therapy and the Treatment of Military Sexual Trauma Jeff Stadler 16. How the Studio and Gallery Experience Benefits Military Members and their Families Jennifer DeLucia Chapter 17. Conclusion Paula Howie.
  • (source: Nielsen Book Data)9781138948662 20170814
For decades, art therapy has proved to be a practical treatment for veterans and other military populations suffering from trauma. Art Therapy with Military Populations provides an in-depth overview of both the theoretical and historical bases of art therapy with these groups while also chronicling the latest trends in treatment and the continued expansion of treatment settings. Edited by an art therapist with over 25 years' experience working with the military and including chapters by a variety of seasoned and innovative clinicians, this comprehensive new volume provides professionals with cutting edge knowledge and interventions for working with military service members and their families. Available for download are employment resources for art therapists who would like to work in military settings, a bonus chapter, historical documents on establishing art therapy, a treatment objectives manual, and resources for art therapists.
(source: Nielsen Book Data)9781138948662 20170814
Green Library
1 online resource : illustrations (black and white)
  • (source: Nielsen Book Data)9780198792079 20170731
Over the past few decades, the use of the arts in health has blossomed. What, for many centuries, was seen as a fringe activity is now being recognised as a field that has enormous potential for impacting positively on both individuals and societies. However, despite this surge in interest and activity, there is still limited support available for people working in the field. Although the number of practical training courses for artists is growing and more universities are establishing research groups, most training activity occurs in either practice or research; there are relatively few opportunities to gain parallel experience in both. Arts in Health: Designing and Researching Interventions provides a complete overview of how to go about undertaking research and practice in the field of arts in health. It starts by exploring the context for arts in health interventions, including the history of the use of arts in health and the theoretical and political developments that have laid the foundations for its flourishing. It also considers what 'arts in health' encompasses and the range of disciplines involved. Part II examines how to design an arts in health intervention, develop partnerships and find funding and considers the sensitivities around working in healthcare. Part III considers the value of research for the field of arts in health and how to design and undertake a research project. Finally, part IV provides a fact file of arts in health research and practice, showing how the arts can be applied and the benefits they can bring across a range of medical disciplines. The book will be valuable for researchers, practitioners, healthcare professionals and those interested in learning more about the field.
(source: Nielsen Book Data)9780198792079 20170731
x, 300 pages, 16 unnumbered pages of plates : illustration (some color) ; 24 cm
  • Adolecent and Adult Outcomes of Childhood Attention Deficit Hyperactivity Disorder : The Montreal Study / Mariya V. Cherkasova, Gabrielle Weiss, and Lily Hechtman
  • Long-term Outcomes of Childhood Attention Deficit Hyperactivity Disorder : The New York Study / Sylvaine Houssais, Lily Hechtman, and Rachel G. Klein
  • The Milwaukee Longitudinal Study of Hyperactive (ADHD) Children / Russell A. Barkley and Mariellen Fischer
  • The Pittsburgh ADHD Longitudinal Study (PALS) / Brooke S.G. Molina, Margaret H. Sibley, Sarah L. Pedersen, and William E. Pelham, Jr.
  • Young Adult Outcome of Attention Deficit Hyperactivity Disorder : Results from the Longitudinal Massachusetts General Hospital Sample of Pediatrically and Psychiatrically Referred Youth with and without ADHD of Both Sexes / Mai Uchida and Joseph Biederman
  • The Berkeley Girls with ADHD Longitudinal Study / Elizabeth B. Owens, Christine A. Zalecki, and Stephen P. Hinshaw
  • The Multimodal Treatment of Children with ADHD (MTA) Follow-up Study : Outcomes and Their Predictors / Arunima Roy and Lily Hechtman
  • Influence of Treatment on Long-term Outcome / Lily Hechtman
  • Summary / Lily Hechtman.
The book provides a comprehensive summary of the best known and most highly respected well-controlled long-term prospective follow-up studies in ADHD. These studies followed children with ADHD and matched controls into young adulthood (mean age 20-25 years) and middle-age (mean age 41 years). They explore a wide variety of outcome areas, e.g. education, occupation, emotional and psychiatric functioning, substance use and abuse, sexual behavior, as well as legal problems. One chapter focuses particularly on the outcome of girls with ADHD. Outcome areas explored are thus comprehensive and clinically very relevant. The book also explores the possible predictors of adult outcome. A whole chapter is devoted to treatment (medication and psychosocial) as a predictor of outcome. In addition to treatment, predictors explored include characteristics of the child (e.g., IQ, severity of initial ADHD symptoms, initial comorbidity characteristics of the family, e.g., socioeconomic status, single parenthood, parental pathology, and family functioning. In a summary chapter, the impact and importance of these various predictors in different outcome areas, e.g. education, occupation, emotional/social functioning, antisocial behavior, substance use and abuse and risky sexual and driving behaviors are explored. In summary, the book provides a comprehensive view of the prognosis, e.g., long-term outcome of ADHD and key factors which can influence this outcome. Professionals and the general public will thus get a clear view of what can happen to children with ADHD as they proceed through adolescence and adulthood and address important prognostic and predictive factors in their treatment approaches to ensure better long-term outcome in patients with ADHD.
(source: Nielsen Book Data)9780190213589 20161124
Green Library