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1 online resource.
3D Bioprinting for Reconstructive Surgery: Techniques and Applications examines the combined use of materials, procedures and tools necessary for creating structural tissue constructs for reconstructive purposes. Offering a broad analysis of the field, the first set of chapters review the range of biomaterials which can be used to create 3D-printed tissue constructs. Part Two looks at the techniques needed to prepare biomaterials and biological materials for 3D printing, while the final set of chapters examines application-specific examples of tissues formed from 3D printed biomaterials. 3D printing of biomaterials for tissue engineering applications is becoming increasingly popular due to its ability to offer unique, patient-specific parts-on demand-at a relatively low cost. This book is a valuable resource for biomaterials scientists, biomedical engineers, practitioners and students wishing to broaden their knowledge in the allied field.
1 online resource.
1 online resource.
  • Front Cover; Biomedical Applications of Functionalized Nanomaterials; Biomedical Applications of Functionalized Nanomaterials; Copyright; Contents; List of Contributors; Preface; REFERENCES; 1
  • From the â#x80; #x9C; Magic Bulletâ#x80; #x9D; to Advanced Nanomaterials for Active Targeting in Diagnostics and Therapeutics; 1. PAUL EHRLICH AND THE â#x80; #x9C; MAGIC BULLETâ#x80; #x9D; ; 2. PASSIVE VERSUS ACTIVE TARGETING IN CANCER AS MODEL; 2.1 SUGARS; 2.2 TRANSFERRIN AND LACTOFERRIN; 2.3 FOLIC ACID; 2.4 HYALURONIC ACID; 2.5 ANTIBODIES; 2.6 APTAMERS; 3. EMERGING CHALLENGES AND PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES
  • I
  • Ligand Selection and Functionalization of Nanomaterials2
  • Conjugation Chemistry Principles and Surface Functionalization of Nanomaterials; 1. CONJUGATION CHEMISTRY IN THE CONTEXT OF BIOMEDICAL NANOMATERIALS; 2. CONJUGATION CHEMISTRY PRINCIPLES; 2.1 AMINE REACTIONS; 2.1.1 Amide Bond Formation: Strategies; Acyl Halides; Acyl Azides; Acylimidazoles; Anhydrides; O-Acylisourea Using Carbodiimides as Coupling Reagents; Active Esters; Staudinger Ligation; Microwave Activation; 2.1.2 Phosphoramidate Formation: Strategies
  • 2.2 THIOL REACTIONS2.2.1 Thioether Bond Formation: Addition of Thiols at Multiple Bonds of Unsaturated Compounds; 2.2.2 Disulfide Bridge; 2.3 HYDROXYL REACTIONS; 2.3.1 Ester Bond Formation: Strategies; Acyl Halides, Anhydrides, and O-Acylisoureas via Carbodiimide Coupling; Mitsunobu Coupling; 2.3.2 Carbamate Linkage Formation: Strategies; 2.4 CARBOXYLIC ACID REACTIONS; 2.5 ALDEHYDES AND KETONES REACTIONS; 2.6 ALKENES AND ALKYNES; 2.6.1 Dielsâ#x80; #x93; Alder Cycloaddition; 2.6.2 Click Chemistry; Huisgen 1,3-Dipolar Azideâ#x80; #x93; Alkyne Cycloadditions; 2.7 PHOTOCHEMICAL REACTIONS
  • 3. SELF-ASSEMBLED MONOLAYERS AS A POWERFUL TOOL FOR THE DESIGN OFâ#x80; S̄URFACE-ENGINEERED NANOMATERIALS3.1 BIOMOLECULES CONJUGATION ONTO SELF-ASSEMBLED MONOLAYERS VIA COVALENT BINDING; 3.1.1 Maleimide-Terminated Self-Assembled Monolayers; 3.1.2 Alkyne or Azide-Terminated Self-Assembled Monolayersâ#x80; (̄â#x80; #x9C; Click Chemistryâ#x80; #x9D; ); 3.1.3 Carboxylic Acid-Terminated Self-Assembled Monolayers; 3.1.4 Hydroxyl-Terminated Self-Assembled Monolayers; 3.2 BIOMOLECULES CONJUGATION ON SELF-ASSEMBLED MONOLAYERS VIAâ#x80; ĀFFINITY BINDING; 4. CHALLENGES IN (BIO)CONJUGATION; REFERENCES
  • 3
  • Ribosome Display Technology for Selecting Peptide and Protein Ligands; 1. INTRODUCTION
Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies.
1 online resource.
  • List of Contributors xi Preface xv Acknowledgments xvii Section 1 Introduction to Biosensors, Recognition Elements, Biomarkers, and Nanomaterials 1 1 General Introduction to Biosensors and Recognition Receptors 3Frank Davis and Zeynep Altintas 1.1 Introduction to Biosensors 3 1.2 Enzyme- Based Biosensors 4 1.3 DNA- and RNA-Based Biosensors 5 1.4 Antibody-Based Biosensors 7 1.5 Aptasensors 8 1.6 Peptide-Based Biosensors 10 1.7 MIP-Based Biosensor 11 1.8 Conclusions 12 References 13 2 Biomarkers in Health Care 17Adama Marie Sesay, Pirkko Tervo, and Elisa Tikkanen 2.1 Introduction 17 2.2 Biomarkers 18 2.2.1 Advantage and Utilization of Biomarkers 18 2.2.2 Ideal Characteristics of Biomarkers 19 2.3 Biological Samples and Biomarkers 20 2.4 Personalized Health and Point-of-Care Technology 22 2.5 Use of Biomarkers in Biosensing Technology 24 2.6 Biomarkers in Disease Diagnosis 26 2.7 Conclusions 29 References 30 3 The Use of Nanomaterials and Microfluidics in Medical Diagnostics 35Jon Ashley and Yi Sun 3.1 Introduction 35 3.2 Nanomaterials in Medical Diagnostics (Bottom-Up Approach) 36 3.2.1 Carbon Nanomaterials 37 3.2.2 Metallic Nanoparticles 39 Quantum Dots 39 Magnetic Nanoparticles (Fe2O3, FeO, and Fe3O4) 41 Gold Nanoparticles 41 Silver Nanoparticles 42 Nanoshells 42 Nanocages 43 Nanowires 43 3.2.3 Polymer-Based Nanoparticles 44 3.3 Application of Microfluidic Devices in Clinical Diagnostics (Top-Down Approach) 45 3.3.1 Unique Features of Microfluidic Devices 45 3.3.2 Applications of Microfluidic Devices in Medical Diagnostics 46 Types of Microfluidic POC Devices 47 Benchtop Microfluidic Instruments 47 Small, Lightweight Microfluidic Devices 49 Simple Un-instrumented Microfluidic Systems 50 3.4 Integration of Microfluidics with Nanomaterials 52 3.5 Future Perspectives of Nanomaterial and Microfluidic-Based Diagnostics 53 References 54 Section 2 Biosensor Platforms for Disease Detection and Diagnostics 59 4 SPR-Based Biosensor Technologies in Disease Detection and Diagnostics 61Zeynep Altintas and Wellington M. Fakanya 4.1 Introduction 61 4.2 Basic Theoretical Principles 63 4.3 SPR Applications in Disease Detection and Diagnostics 66 4.3.1 SPR Biosensors in Cancer Detection 66 4.3.2 SPR Sensors in Cardiac Disease Detection 68 4.3.3 SPR Sensors in Infectious Disease Detection 71 4.4 Conclusions 72 References 74 5 Piezoelectric-Based Biosensor Technologies in Disease Detection and Diagnostics 77Zeynep Altintas and Noor Azlina Masdor 5.1 Introduction 77 5.2 QCM Biosensors 78 5.3 Disease Diagnosis Using QCM Biosensors 80 5.3.1 Cancer Detection Using QCM Biosensors 82 5.3.2 Cardiovascular System Disorder Detection Using Biosensors 85 5.3.3 Pathogenic Disease Detection Using QCM Biosensors 88 5.4 Conclusions 90 References 91 6 Electrochemical-Based Biosensor Technologies in Disease Detection and Diagnostics 95Andrea Ravalli and Giovanna Marrazza 6.1 Introduction 95 6.2 Electrochemical Biosensors: Definitions, Principles, and Classifications 96 6.3 Biomarkers in Clinical Applications 102 6.3.1 Electrochemical Biosensors for Tumor Markers 102 6.3.2 Electrochemical Biosensors for Cardiac Markers 110 6.3.3 Electrochemical Biosensors for Autoimmune Disease 115 6.3.4 Electrochemical Biosensors for Autoimmune Infectious Disease 116 6.4 Conclusions 118 References 118 7 MEMS-Based Cell Counting Methods 125Mustafa Kangul, Eren Aydin, Furkan Gokce, Ozge Zorlu, Ebru Ozgur, and Haluk Kulah 7.1 Introduction 125 7.2 MEMS-Based Cell Counting Methods 126 7.2.1 Optical Cell Counting Methods 126 Quantification of the Cells by Detecting Luminescence 127 Quantification of the Cells via High-Resolution Imaging Techniques 130 7.3 Electrical and Electrochemical Cell Counting Methods 131 7.3.1 Impedimetric Cell Quantification 133 7.3.2 Voltammetric and Amperometric Cell Quantification 135 7.4 Gravimetric Cell Counting Methods 136 7.4.1 Deflection-Based Cell Quantification 136 7.4.2 Resonant-Based Cell Quantification 138 Theory of the Resonant-Based Sensors 138 Actuation and Sensing Methods of Resonators in MEMS Applications 140 Resonator Structure Types Used for Cell Detection Applications 145 7.5 Conclusion and Comments 149 References 151 8 Lab-on-a-Chip Platforms for Disease Detection and Diagnosis 155Ziya Isiksacan, Mustafa Tahsin Guler, Ali Kalantarifard, Mohammad Asghari, and Caglar Elbuken 8.1 Introduction 155 8.2 Continuous Flow Platforms 156 8.3 Paper-Based LOC Platforms 161 8.4 Droplet-Based LOC Platforms 166 8.5 Digital Microfluidic-Based LOC Platforms 169 8.6 CD-Based LOC Platforms 172 8.7 Wearable LOC Platforms 174 8.8 Conclusion and Outlook 176 References 177 Section 3 Nanomaterial's Applications in Biosensors and Diagnostics 183 9 Applications of Quantum Dots in Biosensors and Diagnostics 185Zeynep Altintas, Frank Davis, and Frieder W. Scheller 9.1 Introduction 185 9.2 Quantum Dots: Optical Properties, Synthesis, and Surface Chemistry 186 9.3 Biosensor Applications of QDs 187 9.4 Other Biological Applications of QDs 191 9.5 Water Solubility and Cytotoxicity 194 9.6 Conclusion 196 References 197 10 Applications of Molecularly Imprinted Nanostructures in Biosensors and Diagnostics 201Deniz Aktas-Uygun, Murat Uygun, and Sinan Akgol 10.1 Introduction 201 10.2 Molecular Imprinted Polymers 202 10.3 Imprinting Approaches 204 10.4 Molecularly Imprinted Nanostructures 205 10.5 MIP Biosensors in Medical Diagnosis 207 10.6 Diagnostic Applications of MIP Nanostructures 210 10.7 Conclusions 212 References 213 11 Smart Nanomaterials: Applications in Biosensors and Diagnostics 219Frank Davis, Flavio M. Shimizu, and Zeynep Altintas 11.1 Introduction 219 11.2 Metal Nanoparticles 221 11.3 Magnetic Nanoparticles 226 11.4 Carbon Nanotubes 231 11.5 Graphene 235 11.6 Nanostructured Metal Oxides 242 11.7 Nanostructured Hydrogels 247 11.8 Nanostructured Conducting Polymers 254 11.9 Conclusions and Future Trends 260 References 262 12 Applications of Magnetic Nanomaterials in Biosensors and Diagnostics 277Zeynep Altintas 12.1 Introduction 277 12.2 MNP-Based Biosensors for Disease Detection 279 12.3 MNPs in Cancer Diagnosis and Therapy 284 12.4 Cellular Applications of MNPs in Biosensing, Imaging, and Therapy 289 12.5 Conclusions 290 References 291 13 Graphene Applications in Biosensors and Diagnostics 297Adina Arvinte and Adama Marie Sesay 13.1 Introduction 297 13.2 Graphene and Biosensors 298 13.2.1 Structure 298 13.2.2 Preparation 299 13.2.3 Properties 301 13.2.4 Commercialization in the Field of Graphene Sensors 302 13.2.5 Latest Developments in Graphene-based Diagnosis 303 13.3 Medical Applications of Graphene 303 13.3.1 Electrochemical Graphene Biosensors for Medical Diagnostics 304 Glucose Detection 304 Cysteine Detection 307 Cholesterol Detection 309 Hydrogen Peroxide (H2O2) 310 Glycated Hemoglobin 312 Neurotransmitters 312 Amyloid-Beta Peptide 315 13.3.2 Electrochemical Graphene Aptasensors 316 Nucleic Acids 316 Cancer Cell 318 13.3.3 Optical Graphene Sensors for Medical Diagnostics 319 13.4 Conclusions 322 Acknowledgments 322 References 322 Section 4 Organ-Specific Health Care Applications for Disease Cases Using Biosensors 327 14 Optical Biosensors and Applications to Drug Discovery for Cancer Cases 329Zeynep Altintas 14.1 Introduction 329 14.2 Biosensor Technology and Coupling Chemistries 332 14.3 Optical Biosensors for Drug Discovery 335 14.4 Computational Simulations and New Approaches for Drug-Receptor Interactions 341 14.5 Conclusions 343 References 344 15 Biosensors for Detection of Anticancer Drug-DNA Interactions 349Arzum Erdem, Ece Eksin, and Ece Kesici 15.1 Introduction 349 15.2 Electrochemical Techniques 351 15.3 Optical Techniques 356 15.4 Electrochemical Impedance Spectroscopy Technique 358 15.5 QCM Technique 360 15.6 Conclusions 361 Acknowledgments 361 References 361 Index.
  • (source: Nielsen Book Data)9781119065012 20171204
Provides a broad range of information from basic principles to advanced applications of biosensors and nanomaterials in health care diagnostics This book utilizes a multidisciplinary approach to provide a wide range of information on biosensors and the impact of nanotechnology on the development of biosensors for health care. It offers a solid background on biosensors, recognition receptors, biomarkers, and disease diagnostics. An overview of biosensor-based health care applications is addressed. Nanomaterial applications in biosensors and diagnostics are included, covering the application of nanoparticles, magnetic nanomaterials, quantum dots, carbon nanotubes, graphene, and molecularly imprinted nanostructures. The topic of organ-specific health care systems utilizing biosensors is also incorporated to provide deep insight into the very recent advances in disease diagnostics. Biosensors and Nanotechnology: Applications in Health Care Diagnostics is comprised of 15 chapters that are presented in four sections and written by 33 researchers who are actively working in Germany, the United Kingdom, Italy, Turkey, Denmark, Finland, Romania, Malaysia and Brazil. It covers biomarkers in healthcare; microfluidics in medical diagnostics; SPR-based biosensor techniques; piezoelectric-based biosensor technologies; MEMS-based cell counting methods; lab-on-chip platforms; optical applications for cancer cases; and more. Discusses the latest technology and advances in the field of biosensors and their applications for healthcare diagnosticsParticular focus on biosensors for cancerSummarizes research of the last 30 years, relating it to state-of-the-art technologies Biosensors and Nanotechnology: Applications in Health Care Diagnostics is an excellent book for researchers, scientists, regulators, consultants, and engineers in the field, as well as for graduate students studying the subject.
(source: Nielsen Book Data)9781119065012 20171204
viii, 499 pages : illustrations ; 22 cm
This volume completes a trilogy (Lee, 2012, 2017) on the philosophy of medicine, Western and Chinese. Its immediate prequel (Lee, 2017) sets out in general outline the philosophical and methodological core of Classical Chinese Medicine (CCM); this volume fleshes out that "skeleton" by examining in detail its peculiar concepts and characteristics, such as Getihua/Personalised Medicine, Preventive Medicine, Tianren-xiangying (Macro-Micro-cosmic Wholism), Zheng-Fang Wholism (Wholism at the level of diagnosis and treatment), and Mind-Body Wholism (the person as primitive concept). CCM is here shown to instantiate "ecosystem science", which is post-Newtonian in orientation, departing from familiar Newtonian landmarks such as Reductionism and linearity, resting on thing-ontology for a non-reductionist, non-linear science. This approach highlights a rich irony and paradox: namely, how CCM in being backward-looking (relying on classical texts as foundational texts and prescriptions of some two thousand years standing) simultaneously manages to be at the cutting edge of scientific thinking today.
(source: Nielsen Book Data)9781527503977 20180409
SAL3 (off-campus storage)
268 pages, xvi pages of plates : illustrations (chiefly color) ; 22 cm
  • Préface, Pierre Échinard -- Le médecin histoire d'une vie -- De Grenoble à Marseille -- Les premières années -- Une carrière fulgurante -- Les années noires -- L'aventure égyptienne -- Premières mesures d'urgence -- Abou-Zabel, centre hospitalier et universitaire -- L'hôpital d'Abou-Zabel -- Les ambulances de campagne -- L'École de Médecine d'Abou-Zabel -- Installation des autres Écoles à Abou-Zabel -- Le service de santé de la marine -- La médecine civile -- La vaccination antivariolique -- L'épidémie de choléra de 1831 -- La peste de 1834-1835 -- Le service de santé dans les provinces -- Médecins et charlatans -- Les maladies vénériennes -- Le second souffle -- Premier voyage en Europe -- Transfert de l'hôpital et de l'école de médecine au Caire -- Ministère et commission de l'instruction publique -- Quelques mois de vacances -- La campagne de Syrie -- Retour au Caire -- Deuxième voyage en Europe -- Les dernières années -- L'après Méhémet-Ali -- La disgrâce et le retour à Marseille (1849-1856) -- Deux ans pour reconstruire (1856-1858) -- Une retraite bien méritée -- Un homme aux multiples facettes -- L'homme -- Rigueur et intransigeance -- Un égo surdimensionné -- Une immense générosité -- Des convictions religieuses à toute épreuve -- Fidèle et reconnaissant -- Un parfait homme du monde -- Francs-maçons et saint-simoniens -- Vous avez dit français ? -- Le proche de Méhemet-Ali -- Un despote éclairé -- La reconstruction -- Le bras de fer -- Clot-Bey et la politique: le porte-parole déguisé -- L'homme de science -- Premières prises de position -- Non contagiosité contre contagiosité du choléra et de la peste -- Et bien d'autres maladies -- La vie affective -- Sa mère -- Sa vie sentimentale -- Généreux, mais proche de ses intérêts -- Le collectionneur -- Le jardin botanique -- Le cabinet d'histoire naturelle -- Le collectionneur d'antiquités égyptiennes -- Une collection de monnaies et médailles -- Les honneurs.
"Né à Grenoble en 1793, Antoine-Barthélemy Clot se rend en 1813 à Marseille pour étudier la médecine. Docteur en médecine en 1820 à Montpellier, il est docteur en chirurgie en 1823. Doté d'une forte personnalité, il a déjà été évincé de ses postes hospitaliers et de la Société académique de médecine de Marseille lorsque, en 1825, il est recruté par Tourneau, un Français au service du pacha d'Égypte Méhémet Ali, en tant que médecin et chirurgien en chef de l'armée de ce dernier. Antoine-Barthélemy Clot s'embarque le 21 janvier 1825. Son contrat, prévu pour cinq ans, se prolongera jusqu'en 1849. Clot a été le maître d'oeuvre de la modernisation des institutions médicales égyptiennes. Il crée un Conseil de santé et un service sanitaire militaire, puis fonde un gigantesque complexe hospitalier à Abou-Zabel, ainsi qu'une École de médecine ; il développe la vaccination antivariolique et fonde une École de sages-femmes. Après l'épidémie de choléra de 1832, son dévouement exemplaire lui vaut d'être fait bey par Méhémet Ali. Clot-Bey avait acquis une importante collection d'antiquités égyptiennes, qu'il a cédée à la ville de Marseille. On peut aujourd'hui en admirer les pièces au musée de la Vieille Charité. Cette biographie, qui se fonde sur une documentation exhaustive, retrace la vie de l'homme et du médecin et dresse un portrait nuancé de ce personnage plein de contrastes, qui a contribué à écrire l'une des pages les plus importantes du développement de l'Égypte moderne."--Page 4 of cover.
SAL3 (off-campus storage)
264 pages : illustrations, maps, charts, facsimiles ; 24 cm
  • Enquête documentaire -- Plan de l'exposé -- Chassé-croisé de deux épidémies, itinéraires de la contagion et réponses institutionnelles : 1816-1900 -- Les manifestations des épidémies -- Chronotopie de la fièvre jaune -- Les fièvres gardiennes des côtes africaines -- La marche cyclique de la fièvre jaune -- Les manifestations du choléra en Sénégambie -- L'épidémie de 1868 -- L'épidémie de 1868-1869 à Saint-Louis -- La première phase dé l'épidémie à Saint-Louis (25 novembre 31 décembre 1868) -- La période d'accalmie (de janvier à juin 1869) -- La troisième phase de l'épidémie à Saint-Louis -- L'épidémie de 1868 dans le reste de la colonie -- L'épidémie dans l'ouest de la vallée du fleuve Sénégal (décembre 1868 mai 1869) -- Le choléra dans le Fouta central et dans le Haut-Fleuve (janvier-juin 1869) -- L'épidémie de choléra de 1893 -- L'épidémie à Saint-Louis et dans les postes et escales du fleuve -- Bilan démographique de l'épidémie -- Facteurs d'éclosion des maladies et discours -- Les facteurs d'éclosion des maladies -- Les facteurs naturels de la dégradation de l'hygiène -- Du poids des sécheresses et des inondations -- Les facteurs socio-économiques -- Les facteurs sociaux -- Les conditions de logement -- L'ouverture de la colonie aux influences extérieures : de la logistique transatlantique au chemin de fer -- Savoir médical et discours social autour du choléra et de la fièvre jaune -- La constitution du savoir médical -- Du discours social -- Les représentations du choléra chez le corps médical français -- Les représentations de la fièvre jaune chez le corps médical français -- Les pastoriens et la fièvre jaune -- L'impact des épidémies sur la colonie -- L'impact économique -- La crise économique et le déficit de la production agricole, 1868 -- La guerre de la gomme -- La crise financière : ajournement des rentrées de recettes fiscales -- Les conséquences politiques -- Le choléra et la propagande politico-religieuse -- L'émigration, une forme de contestation politique -- La résurgence des mouvements messianiques en 1868 -- La guerre sainte des Madyankés -- Les réponses du pouvoir colonial -- Les infrastructures -- L'hôpital militaire de Saint-Louis -- L'hospice civil de Saint-Louis -- Les infrastructures de Dakar et de Gorée -- Le laboratoire de microbiologie -- La mise en fonctionnement de rouages institutionnels -- Le Conseil de Santé -- Les commissions sanitaires -- Les conseils d'hygiène et de salubrité publique -- L'élaboration d'un cadre réglementaire -- Des décrets pour contrôler les frontières -- Un dispositif de contrôle administratif -- Réactions des indigènes aux mesures sanitaires -- Les autres mesures de lutte -- L'exemple de Saint-Louis -- Cas de Dakar -- Les mesures de lutte contre l'épidémie -- Le traitement du choléra en 1893 -- La fièvre jaune en question : discours et pratiques des élites coloniales (1900-1960) -- Les manifestations de la fièvre jaune en 1900 et 1927 -- L'épidémie de 1900 -- Un terrain favorable -- Géographie de l'épidémie de 1900 -- Les mesures de défense -- L'épidémie de 1927 -- Géographie de l'épidémie -- Les mesures de défense
  • Les répercussions des épidémies -- Désertion et évitement : l'affaire Chaudié -- La presse "métropolitaine" et le traitement de l'épidémie de 1927 -- Idéologies coloniales ou figures et représentations de la victime -- Immobilisme scientifique en France et aux colonies -- La recherche médicale en panne -- La remise en cause des certitudes -- L'ébranlement du mythe de l'immunité raciale du Noir -- Les réponses médicales et politiques -- La recherche médicale -- Les efforts concertés -- La mission du Sénégal -- La mission sanitaire de Rio de Janeiro -- La Conférence africaine intercoloniale sur la fièvre jaune, 1928 -- Une nouvelle piste : le savoir indigène interrogé par l'Administration, 1932 -- Connaissance indigène de la maladie -- Les traitements de la maladie -- Les instruments de la politique sanitaire : les institutions scientifiques et techniques -- Création d'un enseignement médical spécialisé -- Le transfert à Dakar du laboratoire de microbiologie -- L'hôpital central indigène et l'Institut d'Hygiène sociale -- La réorganisation du Service de Santé -- La lutte contre le moustique -- Les mesures d'ordre administratif -- Le financement de la santé -- Le programme d'assainissement -- Le temps de la victimisation : le Noir comme réservoir de virus (1927-1960) -- La surveillance des Noirs -- Les Syriens, de nouveaux boucs émissaires -- Vaccin et vaccination antiamarile au Sénégal (1927-1952) -- La longue marche vers la découverte d'un vaccin -- La fausse piste : le vaccin de Noguchi -- La première révolution : le remplacement du Macacus rhesus par la souris et les tests de séro-protection -- Le stade expérimental du vaccin : les cobayes humains -- La reconnaissance de la validité scientifique du vaccin français sur le plan international -- Les effets bénéfiques de la vaccination -- Les vaccinations réalisées en AOF de 1934 à 1952 -- Les moyens de l'imposition de la vaccination -- Le "rideau biologique" contre la fièvre jaune -- Contrôle de l'espace et de la société -- De la séparation de l'habitat à la ségrégation raciale -- La partition administrative : Dakar séparée de la colonie -- La lutte antistégomyenne dans la presqu'île du Cap-Vert -- Une zone d'exclusion d'endémicité amarile : une fuite en avant ? -- Le projet de délimitation -- L'exécution du projet -- Le contrôle du port -- Le contrôle de l'aéroport.
"Les épidémies de fièvre jaune et de choléra ont eu une influence considérable sur la vie politique et sociale de la colonie du Sénégal. Comme un coup de projecteur, elles ont fait resurgir à la surface des problèmes sociopolitiques latents. Elles ont permis également de mieux cerner la dynamique de la médecine coloniale, de comprendre les stratégies et les politiques sanitaires mises en oeuvre dans le cadre du projet colonial. La transplantation de la médecine occidentale dans un milieu particulièrement morbide s'est heurtée à plusieurs difficultés, notamment les conflits d'intérêt entre les groupes sociaux (commerçants, indigènes, politiciens et techniciens de la santé). La pluralité des recours thérapeutiques et la négation des pratiques indigènes par l'administration coloniale ont également été une constante dans l'implantation de la nouvelle médecine. Cet ouvrage est une réflexion novatrice sur le cheminement de la pensée médicale et des stratégies politiques coloniales. Il s'inscrit dans le courant de l'histoire sociale, en privilégiant les interactions entre groupes sociaux et leurs rapports à la santé. La célébration de l'élite médicale et des innovations scientifiques cède la place à de larges mises en contexte qui intègrent, outre l'état des connaissances et de la pratique médicales, les dimensions économiques, politiques, sociales et culturelles de la santé. L'analyse du discours des élites permet de mettre à jour les connaissances sur les idéologies coloniales ainsi que sur la perception culturelle de la maladie chez les différents groupes sociaux. Le présent livre dévoile en définitive dans toute sa splendeur, les ressorts de la bio-politique et de l'ordre colonial."--Page 4 of cover.
SAL3 (off-campus storage)
xvi, 368 pages : illustrations (some color) ; 22 cm.
  • Part IChapter 1. PrologueChapter 2. The Context of Health Communication: Global, Local and TheoreticalPart II.Chapter 3. Methodological Issues: Approaches, Pitfalls and SolutionsPart III.Chapter 4. Islands of Good PracticeChapter 5. Language Diversity in the Clinic: Promoting and Exploring Cultural BrokerageChapter 6. Verbal and Non-Verbal Dimensions of the Intercultural Health SettingPart IV.Chapter 7. Putting It All Into Practice: Some Examples and AdviceChapter 8. Conclusions and Implications: Paradoxes and Principles.
  • (source: Nielsen Book Data)9781137580993 20180403
This book offers a novel approach to understanding the complexities of communication in culturally and linguistically diverse health care contexts. It marks the culmination of two decades of research in South Africa, a context that has obvious application in a wider international climate given current globalization and migration trends. The authors draw from a large body of evidence based across different sites and illnesses, scrutinising both the language dynamics of intercultural health interactions and the perceptions and narratives of multiple participants. Including a range of theoretical, methodological and empirical considerations, the volume sheds light upon qualitative research methods and their application in the intercultural context. This book will be a valuable resource for health professionals, medical educators and language practitioners as well as students and scholars of discourse analysis and the medical humanities.
(source: Nielsen Book Data)9781137580993 20180403
Green Library
xxvii, 384 pages : illustrations ; 22 cm
Green Library
xv, 147 pages ; 24 cm
  • Preface Introduction Chapter 1: An Overview of the Debate Chapter 2: Kant's Conception of Dignity and How it Fails to Capture Survivors' Claims of Harm Chapter 3: On Finding an Adequate Conception of Dignity Chapter 4: Trauma, the Self, and Controlling the Nazi Data Chapter 5: Nazi Data: Transparent, Evil, and Transparently Evil Chapter 6: Epistemic Injustice and the Survivors' Claims to Moral Expertise Bibliography.
  • (source: Nielsen Book Data)9781498550024 20180416
In this work, Carol V.A. Quinn (re)constructs the survivors' arguments in the debate concerning the ethics of using Nazi medical data, showing what it would mean to take their claims seriously. She begins with a historical case and presents arguments that help make sense of the following claims: 1) Using the data harms the survivors by violating their dignity; 2) The survivors are the "living data, " and so when we use the data we use them; 3) The data is really, not merely symbolically, evil and we become morally tainted when we engage it; and 4) The survivors are the real moral experts in this debate, and so we should take seriously what they say. Quinn's approach is interdisciplinary, incorporating philosophy, psychology, trauma research, survivors' testimony, Holocaust poetry, literature, and the Hebrew Bible.
(source: Nielsen Book Data)9781498550024 20180416
Green Library
1 online resource.
  • 1. Introduction to electrofluidodynamic techniques Part I: Process optimization 2. Introduction to electrofluidodynamic techniques. Part II: cell to cell/material interactions 3. Melt electrospinning 4. Biofabrication via integrated 3D printing and electrospinning 5. Pyro-Electrohydrodynamic Spinning for micro and nano Patterning 6. Multilayered scaffolds for interface tissue engineering applications 7. air-flow electrofluidodynamics 8. Electrospinning and Microfluidics: an integrated approach for tissue engineering and cancer 9. Electrospun fibres for drug and molecular delivery 10. Additive Electrospraying for scaffold functionalization 11. Bioactive fibres for bone regeneration 12. Design of electrospun fibrous patches for myocardium regeneration 13. Hydrogel fibrous scaffolds for accelerated wound healing 14. Natural polymer based electrospun fibres for antibacterial use 15. Electrospun patches for skin regeneration 16. Multifilament Electrospun devices for ligaments regeneration 17. 3D conduits for peripheral nerve regeneration 18. Inorganic nanoparticles for teranostic use 19. Advances on the use of Electrospun fibres for central Nervous System.
  • (source: Nielsen Book Data)9780081017456 20180312
Electrofluidodynamic Technologies (EFDTs) for Biomaterials and Medical Devices: Principles and Advances focuses on the fundamentals of EFDTs - namely electrospinning, electrospraying and electrodynamic atomization - to develop active platforms made of synthetic or natural polymers for use in tissue engineering, restoration and therapeutic treatments. The first part of this book deals with main technological aspects of EFDTs, such as basic technologies and the role of process parameters. The second part addresses applications of EFDTs in biomedical fields, with chapters on their application in tissue engineering, molecular delivery and implantable devices. This book is a valuable resource for materials scientists, biomedical engineers and clinicians alike.
(source: Nielsen Book Data)9780081017456 20180312
23 PDFs (xxvi, 382 pages)
  • Chapter 1. Introduction and current status of technology in teaching and learning of allied healthcare students: use of technology in teaching and learning of allied healthcare students
  • Chapter 2. The scholarship of learning and teaching in the dynamic discipline of pharmacology and chemistry
  • Chapter 3. The use of digital software applications and digital atlases to supplement anatomy teaching to undergraduate allied health students
  • Chapter 4. Evolving dietetics education to respond to emerging technologies in nutritional genomics
  • Chapter 5. The use of an online adaptive learning platform as an adjunct to live simulated clinical encounters
  • Chapter 6. Current and emerging tools for flexible remote learning
  • Chapter 7. Integration of e-learning technologies: rpi, e-portfolio, and virtual reality in medical laboratory science
  • Chapter 8. Virtual microscopy in haematology and histopathology education: virtual microscopy in science education
  • Chapter 9. Technology associated with dental prosthetics and learning experiences: collaborative initiative, Australian and Norwegian
  • Chapter 10. Simulated learning environments to prepare for clinical placements: transition to placement (t2p)
  • Chapter 11. Use of e-portfolios in health professions education
  • Chapter 12. Digital approaches to embedding employability
  • Chapter 13. Implementing emerging technologies to support work-integrated learning in allied health education: the journey from exploration to adoption
  • Chapter 14. Digital technologies for teaching for allied healthcare students and future directions.
The Internet serves as an essential tool in promoting health awareness through the circulation of important research among the medical professional community. While digital tools and technologies have greatly improved healthcare, challenges are still prevalent among diverse populations worldwide. Emerging Technologies and Work-Integrated Learning Experiences in Allied Health Education is a critical scholarly resource that examines constructivist teaching methods and active learning strategies in allied health education to enhance student knowledge and prepare them for the digital age. Featuring coverage on a broad range of topics, such as e-learning, microscopic morphology, and virtual reality, this book is geared towards researchers, academicians, medical professionals, and upper level students interested in the advancement and dissemination of medical knowledge.
(source: Nielsen Book Data)9781522538509 20180226
1 online resource (567 p.) : ill. (some col.)
  • Mesenchymal stem cells for tissue regeneration / Guang Yang, Song Li and Ngan F. Huang
  • Delivery vehicles for deploying mesenchymal stem cells in tissue repair / Ben P. Hung, Michael S. Friedman and J. Kent Leach
  • Stem cells for cardiac tissue engineering / Jennifer L. Young, Karen L. Christman and Adam J. Engler
  • Engineered mechanical factors to mature pluripotent stem cell-derived cardiomyocytes / Alexandre J.S. Ribeiro, Robin E. Wilson and Beth L. Pruitt
  • Cardiovascular system : stem cells in tissue-engineered blood vessels / Rajendra Sawh-Martinez [and 5 others]
  • Stem cell-derived endothelial cells for cardiovascular regeneration / Luqia Hou and Ngan F. Huang
  • Angiogenic cytokines in the treatment of ischemic heart disease / Michael J. Paulsen and Y. Joseph Woo
  • Adipose tissue engineering and stem cells / D. Adam Young, Brian Mailey, Jennifer Baker, Anne M. Wallace and Karen L. Christman
  • Engineering cartilage : from materials to small molecules / Jeannine M. Coburn and Jennifer H. Elisseeff
  • Adult stem cells for articular cartilage tissue engineering / Sushmita Saha, Jennifer Kirkham, David Wood, Stephen Curran and Xuebin B. Yang
  • Stem cells for disc repair / Ann Ouyang, Aliza A Allon, Zorica Buser, Sigurd Berven and Jeffrey C. Lotz
  • Clinical applications of a stem cell-based therapy for oral bone reconstruction / Thomas Eshraghi and Bradley McAllister
  • Skeletal tissue engineering : progress and prospects / Nicholas J. Panetta, Deepak M. Gupta and Michael T. Longaker
  • Recent advances and future perspectives on cell reprogramming / Bilal Cakir, Kun-Yong Kim and In-Hyun Park
  • High-throughput systems for stem cell engineering / David A. Brafman, Karl Willert and Shu Chien
  • Novel methods for characterizing and sorting single stem cells from their tissue niches / Ju Li, Eric Jabart, Sachin Rangarajan and Irina Conboy
  • Label-free microfluidic techniques to isolate and screen single stem cells / Eric Jabart, Karthik Balakrishnan and Lydia L. Sohn
  • Microscale technologies for tissue engineering and stem cell differentiation / Jason W. Nichol [and 5 others]
  • Designing protein-engineered biomaterials for stem cell therapy / Lei Cai and Sarah C. Heilshorn
  • Quality control of autologous cell and tissue-based therapies / Nathalie Dusserre, Todd McAllister and Nicolas L'Heureux
  • Regulatory challenges for cell-based therapeutics / Todd McAllister, Corey Iyican and Nicolas L'Heureux.
"Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students."-- Provided by publisher.
1 online resource.
1 online resource : illustrations (some color).
  • 1. Ceramic Biomaterials: An Introductory overview 2. Development of a Ceramic-Controlled Piezoelectric of Single Disc for Biomedical Applications 3. Ceramics as biomaterials for dental restoration 4. Ceramic biomaterials for tissue engineering 5. Inert ceramics 6. Bioactive glass ceramics 7. Bioceramics as drug delivery system 8. Bioceramics in orthopaedics 9. Mesoporous Ceramics as Drug Delivery Systems 10. Corrosion of Ceramic Materials 11. Nanostructural Bioceramics and applications 12. Bioactive Glass-Ceramic Scaffolds with High-Strength for Orthopedic Applications 13. Synthesis, Microstructure and Properties of High-Strength Porous Ceramics 14. Characterization and stability of bioactive ceramic composite material and bonding to bone 15. Optical behavior of current ceramic systems 16. Long-term clinical success of all-ceramic posterior restorations 17. Reducing the failure potential of ceramic-based restorations: Ceramic inlays, crowns, veneers, and bridges 18. Recent developments in restorative dental ceramics 19. Degradative effects of the biological environment on ceramics 20. Toxicity of Nanomaterials for Biomedical Applications.
  • (source: Nielsen Book Data)9780081022030 20180416
Fundamental Biomaterials: Ceramics provides current information on ceramics and their conversion from base materials to medical devices. Initial chapters review biomedical applications and types of ceramics, with subsequent sections focusing on the properties of ceramics, and on corrosion, degradation and wear of ceramic biomaterials. The book is ideal for researchers and professionals in the development stages of design, but is also helpful to medical researchers who need to understand and communicate the requirements of a biomaterial for a specific application. This title is the second in a three volume set, with each reviewing the most important and commonly used classes of biomaterials and providing comprehensive information on material properties, behavior, biocompatibility and applications. In addition, with the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for large number of students at undergraduate and post graduate levels.
(source: Nielsen Book Data)9780081022030 20180416
xv, 290 pages ; 20cm
A volume exploring the history of medicine across continents and countries from ancient to modern times, examining the changing systems of medicine in Eastern and Western traditions, comparing alternative medical practices, and introducing readers to how historians have captured the multiple approaches to healing adopted by different cultures.
(source: Nielsen Book Data)9780198803188 20180319
Green Library
x, 239 pages : illustrations ; 24 cm.
  • Introduction Petros Bouras-Vallianatos and Sophia Xenophontos PART I The Classical World 1. Alcmaeon and His Addressees: Revisiting the Incipit Stavros Kouloumentas 2. Gone with the Wind: Laughter and the Audience of the Hippocratic Treatises Laurence Totelin 3. The Professional Audiences of the Hippocratic Epidemics: Patient Cases in Hippocratic Scientific Communication Chiara Thumiger PART II The Imperial World 4. Galen's Exhortation to the Study of Medicine: An Educational Work for Prospective Medical Students Sophia Xenophontos 5. An Interpretation of the Preface to Medical Puzzles and Natural Problems 1 by Ps.-Alexander of Aphrodisias in Light of Medical Education Michiel Meeusen PART III The Islamic World 6. The User-Friendly Galen: Hunayn Ibn Ishaq and the Adaptation of Greek Medicine for a New Audience Uwe Vagelpohl 7. Medical Knowledge as Proof of the Creator's Wisdom and the Arabic Reception of Galen's On the Usefulness of the Parts Elvira Wakelnig PART IV The Byzantine World 8. Physician versus Physician: Comparing the Audience of On the Constitution of Man by Meletios and Epitome on the Nature of Men by Leo the Physician Erika Gielen 9. Reading Galen in Byzantium: The Fate of Therapeutics to Glaucon Petros Bouras-Vallianatos.
  • (source: Nielsen Book Data)9781472487919 20180416
This volume focuses on the relationship between Greek medical texts and their audience(s), offering insights into how not only the backgrounds and skills of medical authors but also the contemporary environment affected issues of readership, methodology and mode of exposition. One of the volume's overarching aims is to add to our understanding of the role of the reader in the contextualisation of Greek medical literature in the light of interesting case-studies from various - often radically different - periods and cultures, including the Classical (such as the Hippocratic corpus) and Roman Imperial period (for instance Galen), and the Islamic and Byzantine world. Promoting, as it does, more in-depth research into the intricacies of Greek medical writings and their diverse revival and transformation from the fifth century BC down to the fourteenth century AD, this volume will be of interest to classicists, medical historians and anyone concerned with the reception of the Greek medical tradition.
(source: Nielsen Book Data)9781472487919 20180416
Green Library
1 online resource (852 p.) : ill.
"This unique volume focuses on the "tools" of medical statistics. It contains over 500 concepts or methods, all of which are explained very clearly and in detail. Each chapter focuses on a specific field and its applications. There are about 20 items in each chapter with each item independent of one another and explained within one page (plus references). The structure of the book makes it extremely handy for solving targeted problems in this area. As the goal of the book is to encourage students to learn more combinatorics, every effort has been made to provide them with a not only useful, but also enjoyable and engaging reading. This handbook plays the role of "tutor" or "advisor" for teaching and further learning. It can also be a useful source for "MOOC-style teaching"."--Publisher's website.
1 online resource : illustrations.
Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices.