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• Oxygen: An Element of Many Surprises
• What Are Stereoelectronic Effects, and How Can We Control Them?
• Structural, Spectroscopic, and Chemical Manifestations of Stereoelectronic Effects
• Models and Theoretical Studies of Stereoelectronic Effects
• Organic Chemistry through the Prism of SEs: Functional Groups with One Oxygen
• Organic Chemistry through the Prism of SEs: Functional Groups with Two Oxygens
• O2, O3, CO2: Simple but Surprising Molecules That Take Us beyond 2-Center, 2-Electron Bonds

"Although carbon is considered the central element of organic chemistry, the broader chemical world has one more star player-oxygen. Billions of years of evolution have filled your room with oxygen as countless cyanobacteria and plants work on changing our planet. Oxygen is everywhere-from geology to biology, from the Earth's crust to the ozone layer. This digital primer aims to analyze chemical reactivity through the prism of oxygen chemistry. The key to understanding this chemistry is the lone pairs of oxygen (i.e., the underutilized "idle" electrons that do not directly contribute to the Lewis structure of molecules). By highlighting the many roles of oxygen, we will illustrate how chemistry rises above the limitations of Lewis structures and how electrons stay neither idle nor "lone" even if they are in "lone pairs" when an oxygen atom is near a reaction center. This digital primer will introduce important types of chemical bonding that transcend undergraduate textbooks but that are likely to drive the development of new chemical reactions in the future."-- Provided by publisher

• Students' Attention on Curved Arrows While Evaluating the Plausibility of an Organic Mechanistic Step--Supporting Spatial Thinking in Organic Chemistry Through Augmented Reality - An Explorative Interview Study--Representational Competence Under the Magnifying Glass - The Interplay Between Student Reasoning Skills, Conceptual Understanding, and the Nature of Representation--Fostering Causal Mechanistic Reasoning as a Means of Modelling in Organic Chemistry--Students' Reasoning in Chemistry Arguments and Designing Resources Using Constructive Alignment--From Free Association to Goal-directed Problem-solving - Network Analysis of Students' Use of Chemical Concepts in Mechanistic Reasoning--Epistemic Stances in Action - Students' Reasoning Process While Reflecting About Alternative Reaction Pathways in Organic Chemistry--How Do Students Reason When They Have to Describe the "What" and "Why" of a Given Reaction Mechanism?--In-the-moment Learning of Organic Chemistry During Interactive Lectures Through the Lens of Practical Epistemology Analysis--Flipped Classrooms in Organic Chemistry - A Closer Look at Student Reasoning Through Discourse Analysis of a Group Activity--Systemic Assessment Questions as a Means of Assessment in Organic Chemistry--Variations in the Teaching of Resonance - An Exploration of Organic Chemistry Instructors' Enacted Pedagogical Content Knowledge--Investigation of Students' Conceptual Understanding in Organic Chemistry Through Systemic Synthesis Questions--Disciplining Perception Spatial Thinking in Organic Chemistry Through Embodied Actions--Building Bridges Between Tasks and Flasks - Design of a Coherent Experiment-supported Learning Environment for Deep Reasoning in Organic Chemistry--Assessment of Assessment in Organic Chemistry - Review and Analysis of Predominant Problem Types Related to Reactions and Mechanisms--Developing Machine Learning Models for Automated Analysis of Organic Chemistry Students' Written Descriptions of Organic Reaction Mechanisms--Deveopment of a Generalizable Framework for Machine Learning-based Evaluation of Written Explanations of Reaction Mechanisms from the Post-secondary Organic Chemistry Curriculum--The Central Importance of Assessing "Doing Science" to Research and Instruction.
• (source: Nielsen Book Data)

Reasoning about structure-reactivity and chemical processes is a key competence in chemistry. Especially in organic chemistry, students experience difficulty appropriately interpreting organic representations and reasoning about the underlying causality of organic mechanisms. As organic chemistry is often a bottleneck for students' success in their career, compiling and distilling the insights from recent research in the field will help inform future instruction and the empowerment of chemistry students worldwide. This book brings together leading research groups to highlight recent advances in chemistry education research with a focus on the characterization of students' reasoning and their representational competencies, as well as the impact of instructional and assessment practices in organic chemistry. Written by leaders in the field, this title is ideal for chemistry education researchers, instructors and practitioners, and graduate students in chemistry education.
(source: Nielsen Book Data)

"The Nobel Prize is science's highest award, as is the case with non-science fields too, and it is therefore arguably the most internationally recognized award in the world. This unique set of volumes focuses on summarizing the Nobel Prize within organic chemistry, as well as the specializations within this specialty. Any reader researching the history of the field of organic chemistry will be interested in this work. Furthermore, it serves as an outstanding resource for providing a better understanding of the circumstances that led to these amazing discoveries and what has happened as a result, in the years since"-- Provided by publisher

• 1. Alkanes, composition, constitution, and configuration
• 2. Functional groups
• 3. Electronic structure of organic molecules
• 4. Alkenes and alkynes
• 5. Substitutions on saturated carbon atom
• 6. Nucleophilic additions
• 7. Stereochemistry, symmetry, and molecular chirality
• 8. Derivatives of carboxylic acids
• 9. Electrophilic substitutions
• 10. Pericyclic reactions
• 11. Organic natural products
• 12. Organic supramolecular and supermolecular structures.

This textbook is designed for students of biology, molecular biology, ecology, medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions. .
(source: Nielsen Book Data)

• Frustrated Lewis Pair Catalysis: An Introduction
• Frustrated Lewis Pair Catalyzed Asymmetric Reactions
• FLP Reduction of Carbon Monoxide and Related Reactions
• FLP-Mediated C-H-Activation
• Mechanistic Insight into the Hydrogen Activation by Frustrated Lewis Pairs
• Lewis Acidic Boranes in Frustrated Lewis Pair Chemistry
• Heterogeneous Catalysis by Frustrated Lewis Pairs
• Lewis Acid−Base Pairs for Polymerization Catalysis: Recent Progress and Perspectives
• Frustrated Lewis Pairs Based on Transition Metals
• Radicals in Frustrated Lewis Pair Chemistry
• Frustrated Lewis Pair Pedagogy: Expanding Core Undergraduate Curriculum and Reinforcing Fundamental Thermodynamic Concepts
• Correction to: Frustrated Lewis Pairs Based on Transition Metals.

This volume highlights the latest research in frustrated Lewis pair (FLP) chemistry and its applications. The contributions present the recent developments of the use of FLPs in asymmetric catalysis, polymer synthesis, homogeneous and heterogeneous catalysis, as well as demonstrating their use as a pedagogical tool. The book will be of interest to researchers in academia and industry alike.
(source: Nielsen Book Data)

• Part I: Development of bio-functional middle molecules.-
• 1. Introduction.-
• 2. Total Synthesis, Biological Evaluation and 3D Structural Analysis of Cyclodepsipeptide Natural Products.-
• 3. Development of the Middle-size Molecules for Alkylation to Higher-Order Structures of Nucleic Acids.-
• 4. In Situ Synthesis of Glycoconjugates on Cell Surface: Selective Cell Imaging Using Low-Affinity Glycan Ligands.-
• 5. Assembled mid-sized agents that control intracellular protein-protein interactions.-
• 6. Macrocyclic mid-sized peptides with new chemical modalities.- Part II: Achievement of highly efficient synthesis of bioactive middle molecules.-
• 7. Enantioselective Total Synthesis of Cotylenin.-
• 8. Flow Chemistry for the Construction of Polycyclic Skeleton.-
• 9. Electrochemical Synthesis of Oligosaccharides as Middle-sized Molecules.-
• 10. Efficient Synthesis of Biologically Active Peptides based on Micro-flow Amide Bond Formation.-
• 11. Design and Concise De Novo Synthesis of Artemisinin Analogs.
• (source: Nielsen Book Data)

This book highlights recently discovered aspects of "middle-size molecules, " focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for -conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science. .
(source: Nielsen Book Data)

• 1. Nuclear Chemistry
• 2. Radioactivity
• 3. Nuclear Reaction
• 4. Interaction of Radiation with Matter
• 5. Ionization Counters
• 6. Scintillation Counter
• 7. Non-conventional Detection Techniques
• 8. Sample Preparation for Counting
• 9. Factors Affecting the Counting Efficiency
• 10. Identification of Radioactive Isotopes
• 11. Statistics of Counting
• 12. Health Hazards and Protection
• 13. Radiochemical Separation Techniques
• 14. Hot Atom-Nuclear Reaction. .

This book is designed to serve as a textbook for core courses offered to postgraduate students enrolled in chemistry. This book can also be used as a core or supplementary text for nuclear chemistry courses offered to students of chemical engineering. The book covers various topics of nuclear chemistry like Shell model, fission/fusion reaction, natural radioactive equilibrium series, nuclear reactions carried by various types of accelerators. In addition, it describes the law of decay of radioactivity, type of decay, and interaction of radiation with matter. It explains the difference between ionization counter, scintillation counter and solid state detector. This book also consists of end-of-book problems to help readers aid self-learning. The detailed coverage and pedagogical tools make this an ideal textbook for postgraduate students and researchers enrolled in various chemistry and engineering courses. This book will also be beneficial for industry professionals in the allied fields.
(source: Nielsen Book Data)

• Introduction
• Bioactive compounds from medicinal plants in myanmar
• New techniques of structure elucidation for sesquiterpenes
• Human endogenous natural products.

This book describes current understandings and recent progress in four areas: in the first one, the cytochalasans, a group of fungal derived natural products characterized by a perhydro-isoindolone core fused with a macrocyclic ring are shown to exhibit high structural diversity and a broad spectrum of bioactivities. The second one is dedicated to a description of bioactive compounds from the medicinal plants of Myanmar, the third one is dedicated to new structure elucidation techniques in the field of sesquiterpenes. The last one discusses the endogenous natural products that are produced by human cells including endogenous amines, steroids, and fatty acid derived natural products. The co-metabolism and natural product production of the human microbiome is also described including tryptophan, bile acids, choline, and cysteine.
(source: Nielsen Book Data)

• Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis
• From Plant to Patient: Thapsigargin
• Antileishmanial Activity of Lignans and Neolignans
• Cryptolepine as a Lead to new Antiprotozoal Agents
• Biologically Active Constituents from Plants of the Genus Xanthium.

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
(source: Nielsen Book Data)

• Chapter 1. Marine Biodiscovery in a Changing World.-
• Chapter 2. The Chemistry and Chemical Ecology of Lepidopterans as Investigated in Brazil.-
• Chapter 3. A Timeline of Perezone, the First Isolated Secondary Metabolite in the New World, Covering the Period from 1852 to 2020.-
• Chapter 4. Biologically Acitive Constituents from Plants of the Genus Xanthium.-
• Chapter 5. Biologically Active Constituents from Plants of Genus Desmos.
• (source: Nielsen Book Data)

This volume describes several highly diverse subjects: Chapter 1 explores marine biodiscovery of the North-eastern Atlantic off the coast of Ireland as a model for best practice in research. The second chapter investigates Brazilian Chemical Ecology and examples of insect-plant communication studies that are mediated by natural products demonstrate the beautiful interconnectedness of species in a biome. Our third chapter comprises the advances in the science of the sesquiterpene quinone, perezone, which in 1852 was the first natural product isolated in crystalline form in the New World. The last two chapters are from a Vietnamese group and the first of these follows the phytochemistry, pharmacology, and ethnomedical uses of the genus Xanthium, which produces interesting sulfur and nitrogen containing natural products. Finally, the genus Desmos is discussed, where an overview of its constituent natural products and their in vitro pharmacological potential is described.
(source: Nielsen Book Data)

• 1 UV/Vis Spectroscopy 1.1 Theoretical Introduction 1.2 Sample Preparation and Measurement of Spectra 1.3 Chromophores 1.4 Applications of UV/Vis Spectroscopy 1.5 Derivative Spectroscopy 1.6 Chiroptical Methods
• 2 Infrared and Raman Spectra 2.1 Introduction 2.2 Basic Principles 2.3 Infrared Spectrometer 2.4 Sample Preparation 2.5 Infrared Spectrum 2.6 Characteristic Absorptions: An Overview 2.7 Infrared Absorptions of Single Bonds with Hydrogen 2.8 Infrared Absorptions of Triple Bonds and Cumulated Double Bonds 2.9 Infrared Absorptions of Double Bonds C=O, C=N, N=N, and N=O 2.10 Infrared Absorption of Aromatic Compounds 2.11 Infrared Absorption in the Fingerprint Range 2.12 Examples of Infrared Spectra 2.13 Information Technology Assisted Spectroscopy 2.14 Quantitative Infrared Spectroscopy 2.15 Raman Spectroscopy
• 3 Nuclear Magnetic Resonance Spectroscopy 3.1 Physical Principles 3.2 NMR Spectra and Molecular Structure 3.3 1H NMR Spectroscopy 3.4 13C NMR Spectroscopy 3.5 Combination of 1H and 13C NMR Spectroscopy 3.6 NMR of other Nuclei
• 4 Mass Spectrometry 4.1 Introduction 4.2 General Aspects of Mass Spectrometry 4.3 Instrumental Aspects 4.4 Interpretation of Spectra and Structural Elucidation 4.5 Sample Preparation 4.6 Artifacts 4.7 Tables to the Mass Spectrometry
• 5 Handling of Spectra and Analytical Data: Practical Examples 5.1 Introduction 5.2 Characterization of Compounds 5.3 Structure Elucidation of Allegedly Known Compounds and of Products Arising from Syntheses 5.4 Structure Elucidation of COmpletely Unknown Compounds.
• (source: Nielsen Book Data)

Boost your knowledge of modern spectroscopic methods! This reference work provides you with essential knowledge for the application of modern spectroscopic methods in organic chemistry. All methods are explained based on typical practical examples, theoretical aspects, and applications. The following spectroscopic methods are explained and examples are given: UV/Vis Spectroscopy Infrared (IR) and Raman Spectroscopy Nuclear Magnetic Resonance Spectroscopy (NMR) Mass Spectrometry (MS) The textbook has been a standard reference for decades. As it conveys necessary knowledge for examinations at all universities it is compulsory reading for every organic chemistry student!.
(source: Nielsen Book Data)

• Part I. Nucleation and crystal growth
• X-Ray Birefringence Imaging (XBI): A New Technique for Spatially Resolved Mapping of Molecular Orientations in Materials / Kenneth D. M. Harris, Rhian Patterson, Yating Zhou, Stephen P. Collins
• Direct Visualization of Crystal Formation and Growth Probed by the Organic Fluorescent Molecules / Fuyuki Ito
• Anti-solvent Crystallization Method for Production of Desired Crystalline Particles / Hiroshi Takiyama
• Crystal Nucleation of Proteins Induced by Surface Plasmon Resonance / Tetsuo Okutsu
• Control of Crystal Size Distribution and Polymorphs in the Crystallization of Organic Compounds / Koichi Igarashi, Hiroshi Ooshima
• Managing Thermal History to Stabilize/Destabilize Pharmaceutical Glasses / Kohsaku Kawakami
• Part II. Structure and Design of Crystals
• Supramolecular, Hierarchical, and Energetical Interpretation of Organic Crystals: Generation of Supramolecular Chirality in Assemblies of Achiral Molecules / Mikiji Miyata, Seiji Tsuzuki
• Relationship Between Atomic Contact and Intermolecular Interactions: Significant Importance of Dispersion Interactions Between Molecules Without Short Atom–Atom Contact in Crystals / Seiji Tsuzuki
• Pharmaceutical Multicomponent Crystals: Structure, Design, and Properties / Okky Dwichandra Putra, Hidehiro Uekusa
• The Design of Porous Organic Salts with Hierarchical Process / Norimitsu Tohnai
• Layered Hydrogen-Bonded Organic Frameworks as Highly Crystalline Porous Materials / Ichiro Hisaki, Qin Ji, Kiyonori Takahashi, Takayoshi Nakamura
• Kinetic Assembly of Porous Coordination Networks Leads to Trapping Unstable Elemental Allotropes / Hiroyoshi Ohtsu, Pavel M. Usov, Masaki Kawano
• Creation of Organic-Metal Hybridized Nanocrystals Toward Nonlinear Optics Applications / Tsunenobu Onodera, Rodrigo Sato, Yoshihiko Takeda, Hidetoshi Oikawa
• Part III. Function
• Luminescent Crystal–Control of Excited-State Intramolecular Proton Transfer (ESIPT) Luminescence Through Polymorphism / Toshiki Mutai
• Solid-State Fluorescence Switching Using Photochromic Diarylethenes / Seiya Kobatake, Tatsumoto Nakahama
• Circularly Polarized Luminescence from Solid-State Chiral Luminophores / Yoshitane Imai
• Azulene-Based Materials for Organic Field-Effect Transistors / Hiroshi Katagiri
• Electrochemical Functions of Nanostructured Liquid Crystals with Electronic and Ionic Conductivity / Masahiro Funahashi
• Part IV. Kryptoracemates / Edward R. T. Tiekink
• Twenty-Five Years’ History, Mechanism, and Generality of Preferential Enrichment as a Complexity Phenomenon / Rui Tamura, Hiroki Takahashi, Gérard Coquerel
• Asymmetric Synthesis Involving Dynamic Enantioselective Crystallization / Masami Sakamoto
• Molecular Recognition by Inclusion Crystals of Chiral Host Molecules Having Trityl and Related Bulky Groups / Motohiro Akazome, Shoji Matsumoto
• Asymmetric Catalysis and Chromatographic Enantiomer Separation by Homochiral Metal–Organic Framework: Recent Advances
• Koichi Tanaka
• Part V. Solid-State Polymerization of Conjugated Acetylene Compounds to Form pi-conjugated polymers / Shuji Okada, Yoko Tatewaki, Ryohei Yamakado
• Click Chemistry to Metal-Organic Frameworks as a Synthetic Tool for MOF and Applications for Functional Materials / Kazuki Sada, Kenta Kokado.

This book summarizes and records the recent notable advances in diverse topics in organic crystal chemistry, which has made substantial progress along with the rapid development of a variety of analysis and measurement techniques for solid organic materials. This review book is one of the volumes that are published periodically on this theme. The previous volume, published in 2015, systematically summarized the remarkable progress in assorted topics of organic crystal chemistry using organic solids and organic-inorganic hybrid materials during the previous 5 years, and it has been widely read. The present volume also shows the progress of organic solid chemistry in the last 5 years, with contributions mainly by invited members of the Division of Organic Crystal Chemistry of the Chemical Society of Japan (CSJ), together with prominent invited authors from countries other than Japan.
(source: Nielsen Book Data)

• Chapter 1 Introduction to Chemistry and Organic Chemistry
• Chapter 2 Organic Molecules and Functional Groups
• Chapter 3 Nomenclature of Organic Molecules
• Chapter 4 Acids And Bases
• Chapter 5 Understanding Organic Reactions
• Chapter 6 Stereochemistry
• Chapter 7 Amino Acids And Proteins
• Chapter 8 Carbohydrates
• Chapter 9 Alcohols And Ethers
• Chapter 10 Spectroscopy.
• (source: Nielsen Book Data)

Basic Organic Chemistry discusses the basic concept of chemistry as well as organic chemistry. It includes detailed description of organic molecules, functional groups and the nomenclature of the organic molecules. This book also discusses the notion of acids and bases and stereochemistry of the organic molecules along with the description of amino acids, proteins, carbohydrates, alcohol and ethers. It provides the reader with the insights of basic organic chemistry so as to understand the basic organic reactions and the application of spectroscopy to study organic molecules.
(source: Nielsen Book Data)

• Designing Impactful Green and Sustainable Chemistry Workshops for High School Teachers / Wissinger, Jane E., Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States; Knutson, Cassandra M., White Bear Lake High School, White Bear Lake, Minnesota 55110, United States; Javner, Cassidy H., Shakopee High School, Shakopee, Minnesota 55379, United States / http://dx.doi.org/10.1021/bk-2020-1344.ch001
• Educational Tools to Fight for the Planet: Education Is Our Most Powerful Weapon to Fight Climate Change / Foy, Gregory P., York College of Pennsylvania, 441 Country Club Road, York, Pennsylvania 17403, United States; Hill Foy, R. Leigh, York Suburban High School, 1800 Hollywood Drive, York, Pennsylvania 17403, United States / http://dx.doi.org/10.1021/bk-2020-1344.ch002
• The Green Fuels Depot: Sustainability, Education, and Undergraduate Research at the Community College / Jarman, Richard H., Department of Chemistry, College of DuPage, Glen Ellyn, Illinois 60137, United States / http://dx.doi.org/10.1021/bk-2020-1344.ch003
• Building Bridges between Sustainability and Chemistry in Education and Outreach / Larsen, Sarah C., Department of Chemistry, Fleming Hall, University of Houston, Houston, Texas 77204, United States; Larsen, Russell G., Department of Chemistry, Fleming Hall, University of Houston, Houston, Texas 77204, United States; Grassian, Vicki H., Departments of Chemistry & Biochemistry, Nanoengineering and Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, Mail Code 0314, La Jolla, California 92093, United States / http://dx.doi.org/10.1021/bk-2020-1344.ch004
• Greening the Senior High School Chemistry Curriculum: An Action Research Initiative / Linkwitz, Michael, Otto-Hahn-Gymnasium, Bergisch-Gladbach 51429, Germany; Eilks, Ingo, Department of Biology and Chemistry, University of Bremen, Bremen 28334, Germany / http://dx.doi.org/10.1021/bk-2020-1344.ch005
• Education for Sustainable Development in High School through Inquiry-Type Socio-Scientific Issues / Mamlok-Naaman, Rachel, Department of Science Teaching, Weizmann Institute of Science, Israel; Mandler, Daphna, Department of Science Teaching, Weizmann Institute of Science, Israel / http://dx.doi.org/10.1021/bk-2020-1344.ch006
• Incorporating Sustainability into Chemistry Education by Teaching through Project-Based Learning / Hugerat, Muhamad, The Academic Arab College for Education in Israel-Haifa, 22 Hahashmal Street, Haifa 33145, P.O. Box 8349, Israel / http://dx.doi.org/10.1021/bk-2020-1344.ch007
• Sustainability and Green Chemistry Education: Innovative and Contextualized Experiences from the Undergraduate Chemistry Courses at the Federal University of São Carlos, Brazil / Zuin, Vânia Gomes, Department of Chemistry, Postgraduate Programs in Education and Chemistry, Federal University of São Carlos (UFSCar), Rodovia Washington Luís (SP-310), km 235, 13565-905 São Carlos, Brazil, The University of York, Green Chemistry Centre of Excellence, Heslington, York YO10 5DD, United Kingdom; Gomes, Caroindes Julia Corrêa, Postgraduate Program in Education, Federal University of São Carlos (UFSCar) / http://dx.doi.org/10.1021/bk-2020-1344.ch008
• Evolution of an ACS-CEI Award-Winning Undergraduate Course in Catalytic Organic Chemistry / Rousseaux, Sophie A. L., Department of Chemistry, University of Toronto, Toronto M5S 3H6, Canada; Dicks, Andrew P., Department of Chemistry, University of Toronto, Toronto M5S 3H6, Canada / http://dx.doi.org/10.1021/bk-2020-1344.ch009
• A Holistic Approach to Incorporating Sustainability into Chemistry Education in Israel / Shwartz, Yael, The Departments of Science Teaching, Weizmann Institute of Science, 234 Herzl Street, Rehovot 7610001, Israel; Eidin, Emil, CREATE for STEM Institute, Michigan State University, 620 Farm Lane, East Lansing, Michigan 48825, United States; Marchak, Debora, The Departments of Science Teaching, Weizmann Institute of Science, 234 Herzl Street, Rehovot 7610001, Israel; Kesner, Miri, The Departments of Science Teaching, Weizmann Institute of Science, 234 Herzl Street, Rehovot 7610001, Israel; Green, Neta Avraham, The Departments of Science Teaching, Weizmann Institute of Science, 234 Herzl Street, Rehovot 7610001, Israel; Marom, Eldad, Open University, 1 University Road, P.O. Box 808, Ra'ana 43107, Israel; Cahen, David, The Departments of Science Teaching, Weizmann Institute of Science, 234 Herzl Street, Rehovot 7610001, Israel; Hofstein, Avi, The Departments of Science Teaching, Weizmann Institute of Science, 234 Herzl Street, Rehovot 7610001, Israel, The Arabic Academic College, 22 HeHashmal Street, Haifa 33145, Israel; Dori, Yehudit Judy, Faculty for Education in Science and Technology, Technion, Israel Institute of Technology, Haifa 3200003, Israel, School of Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States / http://dx.doi.org/10.1021/bk-2020-1344.ch010
• Malaysian Experiences of Incorporating Green Chemistry into Teaching and Learning of Chemistry across Secondary and Tertiary Education / Karpudewan, Mageswary, School of Educational Studies, Universiti Sains Malaysia, 11800 USM Penang, Malaysia / http://dx.doi.org/10.1021/bk-2020-1344.ch011
• Editors' Biographies / http://dx.doi.org/10.1021/bk-2020-1344.ot001

A key step toward embracing sustainability and green chemistry is educating the next generation of chemists about their importance. To this aim, the ACS-CEI Award for Incorporation of Sustainability into Chemistry Education recognizes exemplary contributions. This two-volume set contains chapters written by recent award winners. This volume explores current efforts across the world to incorporate environmentally conscious material into chemistry curricula. Educators spanning K-12, undergraduate, and graduate classrooms provide perspectives on new developments as well as methods to introduce preservice and current teachers to environmental teaching best practices.
(source: Nielsen Book Data)

• Chapter 1 Bond-Line Drawings 1 1.1 How to Read Bond-Line Drawings 1 1.2 How to Draw Bond-Line Drawings 4 1.3 Mistakes to Avoid 6 1.4 More Exercises 6 1.5 Identifying Formal Charges 8 1.6 Finding Lone Pairs that are Not Drawn 11 Chapter 2 Resonance 15 2.1 What is Resonance? 15 2.2 Curved Arrows: The Tools for Drawing Resonance Structures 16 2.3 The Two Commandments 17 2.4 Drawing Good Arrows 20 2.5 Formal Charges in Resonance Structures 22 2.6 Drawing Resonance Structures-Step by Step 25 2.7 Drawing Resonance Structures-by Recognizing Patterns 29 2.8 Assessing the Relative Importance of Resonance Structures 36 Chapter 3 Acid-Base Reactions 41 3.1 Factor 1-What Atom is the Charge On? 41 3.2 Factor 2-Resonance 44 3.3 Factor 3-Induction 47 3.4 Factor 4-Orbitals 49 3.5 Ranking the Four Factors 50 3.6 Other Factors 53 3.7 Quantitative Measurement (pKa Values) 54 3.8 Predicting the Position of Equilibrium 54 3.9 Showing a Mechanism 55 Chapter 4 Geometry 57 4.1 Orbitals and Hybridization States 57 4.2 Geometry 60 4.3 Lone Pairs 62 Chapter 5 Nomenclature 64 5.1 Functional Group 65 5.2 Unsaturation 66 5.3 Naming the Parent Chain 67 5.4 Naming Substituents 70 5.5 Stereoisomerism 72 5.6 Numbering 74 5.7 Common Names 78 5.8 Going from a Name to a Structure 79 Chapter 6 Conformations 80 6.1 How to Draw a Newman Projection 80 6.2 Ranking the Stability of Newman Projections 84 6.3 Drawing Chair Conformations 86 6.4 Placing Groups on the Chair 90 6.5 Ring Flipping 93 6.6 Comparing the Stability of Chairs 99 6.7 Don't Be Confused by the Nomenclature 102 Chapter 7 Configurations 103 7.1 Locating Chiral Centers 103 7.2 Determining the Configuration of a Chiral Center 106 7.3 Nomenclature 113 7.4 Drawing Enantiomers 116 7.5 Diastereomers 120 7.6 Meso Compounds 121 7.7 Drawing Fischer Projections 123 7.8 Optical Activity 127 Chapter 8 Mechanisms 129 8.1 Introduction to Mechanisms 129 8.2 Nucleophiles and Electrophiles 129 8.3 Basicity vs. Nucleophilicity 131 8.4 Arrow-Pushing Patterns for Ionic Mechanisms 133 8.5 Carbocation Rearrangements 138 8.6 Information Contained in a Mechanism 142 Chapter 9 Substitution Reactions 145 9.1 The Mechanisms 145 9.2 Factor 1-The Electrophile (Substrate) 147 9.3 Factor 2-The Nucleophile 149 9.4 Factor 3-The Leaving Group 151 9.5 Factor 4-The Solvent 153 9.6 Using All Four Factors 155 9.7 Substitution Reactions Teach Us Some Important Lessons 156 Chapter 10 Elimination Reactions 157 10.1 The E2 Mechanism 157 10.2 The Regiochemical Outcome of an E2 Reaction 158 10.3 The Stereochemical Outcome of an E2 Reaction 159 10.4 The E1 Mechanism 162 10.5 The Regiochemical Outcome of an E1 Reaction 163 10.6 The Stereochemical Outcome of an E1 Reaction 164 10.7 Substitution vs. Elimination 164 10.8 Determining the Function of the Reagent 165 10.9 Identifying the Mechanism(s) 167 10.10 Predicting the Products 169 Chapter 11 Addition Reactions 172 11.1 Terminology Describing Regiochemistry 172 11.2 Terminology Describing Stereochemistry 174 11.3 Adding H and H 180 11.4 Adding H and X, Markovnikov 183 11.5 Adding H and Br, Anti-Markovnikov 188 11.6 Adding H and OH, Markovnikov 192 11.7 Adding H and OH, Anti-Markovnikov 194 11.8 Synthesis Techniques 198 11.9 Adding Br and Br
• Adding Br and OH 204 11.10 Adding OH and OH, Anti 209 11.11 Adding OH and OH, syn 211 11.12 Oxidative Cleavage of an Alkene 213 Summary of Reactions 214 Chapter 12 Alkynes 216 12.1 Structure and Properties of Alkynes 216 12.2 Preparation of Alkynes 218 12.3 Alkylation of Terminal Alkynes 219 12.4 Reduction of Alkynes 221 12.5 Hydration of Alkynes 224 12.6 Keto-Enol Tautomerization 227 12.7 Ozonolysis of Alkynes 232 Chapter 13 Alcohols 234 13.1 Naming and Designating Alcohols 234 13.2 Predicting Solubility of Alcohols 235 13.3 Predicting Relative Acidity of Alcohols 237 13.4 Preparing Alcohols: A Review 239 13.5 Preparing Alcohols via Reduction 240 13.6 Preparing Alcohols via Grignard Reactions 246 13.7 Summary of Methods for Preparing Alcohols 249 13.8 Reactions of Alcohols: Substitution and Elimination 250 13.9 Reactions of Alcohols: Oxidation 253 13.10 Converting an Alcohol into an Ether 255 Chapter 14 Ethers and Epoxides 257 14.1 Introduction to Ethers 257 14.2 Preparation of Ethers 259 14.3 Reactions of Ethers 261 14.4 Preparation of Epoxides 262 14.5 Ring-Opening Reactions of Epoxides 264 Chapter 15 Synthesis 270 15.1 One-Step Syntheses 271 15.2 Multistep Syntheses 283 15.3 Retrosynthetic Analysis 284 15.4 Creating Your Own Problems 285 Detailed Solutions 287 Index 381.
• (source: Nielsen Book Data)

Organic chemistry can be a challenging subject. Most students view organic chemistry as a subject requiring hours upon hours of memorization. Author David Klein's Second Language books prove this is not true-organic chemistry is one continuous story that actually makes sense if you pay attention. Offering a unique skill-building approach, these market-leading books teach students how to ask the right questions to solve problems, study more efficiently to avoid wasting time, and learn to speak the language of organic chemistry. Covering the initial half of the course, Organic Chemistry as a Second Language: First Semester Topics reviews critical principles and explains their relevance to the rest of the course. Each section provides hands-on exercises and step-by-step explanations to help students fully comprehend classroom lectures and textbook content. Now in its fifth edition, this valuable study resource covers the characteristics of molecules, the nature of atomic bonds, the relationships between different types of molecules, drawing and naming molecules, and essential molecular reactions.
(source: Nielsen Book Data)

• Chapter 1 Aromaticity 1 1.1 Introduction to Aromatic Compounds 1 1.2 Nomenclature of Aromatic Compounds 2 1.3 Criteria for Aromaticity 6 1.4 Lone Pairs 9
• Chapter 2 IR Spectroscopy 11 2.1 Vibrational Excitation 11 2.2 IR Spectra 13 2.3 Wavenumber 13 2.4 Signal Intensity 18 2.5 Signal Shape 19 2.6 Analyzing an IR Spectrum 26
• Chapter 3 NMR Spectroscopy 33 3.1 Chemical Equivalence 33 3.2 Chemical Shift (Benchmark Values) 36 3.3 Integration 41 3.4 Multiplicity 44 3.5 Pattern Recognition 46 3.6 Complex Splitting 48 3.7 No Splitting 49 3.8 Hydrogen Deficiency Index (Degrees of Unsaturation) 50 3.9 Analyzing a Proton NMR Spectrum 53 3.10 13C NMR Spectroscopy 57
• Chapter 4 Electrophilic Aromatic Substitution 60 4.1 Halogenation and the Role of Lewis Acids 61 4.2 Nitration 65 4.3 Friedel-Crafts Alkylation and Acylation 67 4.4 Sulfonation 74 4.5 Activation and Deactivation 78 4.6 Directing Effects 80 4.7 Identifying Activators and Deactivators 89 4.8 Predicting and Exploiting Steric Effects 99 4.9 Synthesis Strategies 106
• Chapter 5 Nucleophilic Aromatic Substitution 112 5.1 Criteria for Nucleophilic Aromatic Substitution 112 5.2 SNAr Mechanism 114 5.3 Elimination-Addition 120 5.4 Mechanism Strategies 125
• Chapter 6 Ketones and Aldehydes 127 6.1 Preparation of Ketones and Aldehydes 127 6.2 Stability and Reactivity of C===O Bonds 130 6.3 H-Nucleophiles 132 6.4 O-Nucleophiles 137 6.5 S-Nucleophiles 147 6.6 N-Nucleophiles 149 6.7 C-Nucleophiles 157 6.8 Exceptions to the Rule 166 6.9 How to Approach Synthesis Problems 170
• Chapter 7 Carboxylic Acid Derivatives 176 7.1 Reactivity of Carboxylic Acid Derivatives 176 7.2 General Rules 177 7.3 Acid Halides 181 7.4 Acid Anhydrides 189 7.5 Esters 191 7.6 Amides and Nitriles 200 7.7 Synthesis Problems 209
• Chapter 8 Enols and Enolates 217 8.1 Alpha Protons 217 8.2 Keto-Enol Tautomerism 219 8.3 Reactions Involving Enols 223 8.4 Making Enolates 226 8.5 Haloform Reaction 229 8.6 Alkylation of Enolates 232 8.7 Aldol Reactions 236 8.8 Claisen Condensation 242 8.9 Decarboxylation 249 8.10 Michael Reactions 256
• Chapter 9 Amines 263 9.1 Nucleophilicity and Basicity of Amines 263 9.2 Preparation of Amines Through SN2 Reactions 265 9.3 Preparation of Amines Through Reductive Amination 268 9.4 Acylation of Amines 273 9.5 Reactions of Amines with Nitrous Acid 276 9.6 Aromatic Diazonium Salts 279
• Chapter 10 Diels-Alder Reactions 282 10.1 Introduction and Mechanism 282 10.2 The Dienophile 285 10.3 The Diene 286 10.4 Other Pericyclic Reactions 292 Detailed Solutions S-1 Index I-1.
• (source: Nielsen Book Data)

Organic chemistry can be a challenging subject. Most students view organic chemistry as a subject requiring hours upon hours of memorization. Author David Klein's Second Language books prove this is not true-organic chemistry is one continuous story that actually makes sense if you pay attention. Offering a unique skill-building approach, these market-leading books teach students how to ask the right questions to solve problems, study more efficiently to avoid wasting time, and learn to speak the language of organic chemistry. The fifth edition of Organic Chemistry as a Second Language: Second Semester Topics builds upon the principles previously explored in first half of the course-delving deeper into molecular mechanisms, reactions, and analytical techniques. Hands-on exercises and thoroughly-explained solutions further reinforce student comprehension of chemical concepts and organic principles. An indispensable supplement to the primary text, this resource covers aromatic compounds, infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy, nucleophilic and electrophilic aromatic substitution, ketones and aldehydes, carboxylic acid derivatives, and much more.
(source: Nielsen Book Data)

• Chapter 1. Carbohalogenation Catalyzed by Palladium and Nickel.-
• Chapter 2. Diastereoselective Pd-Catalyzed Aryl Cyanation and Aryl Borylation.-
• Chapter 3. Pd-Catalyzed Spirocyclization via C-H Activation and Benzyne/Alkyne Insertion.
• (source: Nielsen Book Data)

This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon-carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C-H activation and -system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.
(source: Nielsen Book Data) This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon-carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C-H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.

• Sesterterpenoids.- Secondary Metabolites from Marine-Derived Fungi from China.
• (source: Nielsen Book Data)

The first chapter in volume 111 summarizes research on the sesterterpenoids, which are known as a relatively small group of natural products. However, they express a variety of simple to complicated chemical structures. This chapter focuses on the chemical structures of sesterterpenoids and how their structures are synthesized in Nature. The second chapter is devoted to marine-derived fungi, which play an important role in the search for structurally unique secondary metabolites, some of which show promising pharmacological activities that make them useful leads for drug discovery. Marine natural product research in China in general has made enormous progress in the last two decades as described in this chapter on fungal metabolites. This contribution covers 613 new natural products reported from 2001 to 2017 from marine-derived fungi obtained from algae, sponges, corals, and other marine organisms from Chinese waters.
(source: Nielsen Book Data)

• Using Flipped Classroom Settings to Shift the Focus of a General Chemistry Course from Topic Knowledge to Learning and Problem-Solving Skills: A Tale of Students Enjoying the Class They Were Expecting to Hate / Ramella, Daniele, College of Science and Technology-Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122, United States; Brock, Benjamin E., CAT-Center for Advancement of Teaching, Temple University, Philadelphia, Pennsylvania 19122, United States, School of Education, Temple University, Philadelphia, Pennsylvania 19122, United States; Velopolcek, Maria K., Department of Chemistry, Duke University, Durham, North Carolina 27701, United States; Winters, Kyle P., School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States / http://dx.doi.org/10.1021/bk-2019-1322.ch001
• Combining Pre-class Preparation with Collaborative In-Class Activities to Improve Student Engagement and Success in General Chemistry / Blaser, Mark / http://dx.doi.org/10.1021/bk-2019-1322.ch002
• Using Clicker-Based Group Work Facilitated by a Modified Peer Instruction Process in a Highly Successful Flipped General Chemistry Classroom / Pollozi, Shejla, Department of Chemistry, Lehman College of the City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, United States, Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York 10016, United States; Haddad, Ibrahim, Department of Chemistry, Lehman College of the City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, United States; Tyagi, Aanchal, Department of Chemistry, Lehman College of the City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, United States; Mills, Pamela, Department of Chemistry, Lehman College of the City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, United States, Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York 10016, United States; McGregor, Donna, Department of Chemistry, Lehman College of the City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, United States, Ph.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York 10016, United States / http://dx.doi.org/10.1021/bk-2019-1322.ch003
• Maximizing Learning Efficiency in General Chemistry / Cracolice, Mark S., Department of Chemistry & Biochemistry, University of Montana, Missoula, Montana 59812, United States; Queen, Matt, Department of Biological and Physical Sciences, Montana State University Billings, 1500 University Drive, Billings, Montana 59101, United States / http://dx.doi.org/10.1021/bk-2019-1322.ch004
• Flipping General Chemistry in Small Classes: Students' Perception and Success / Hutchinson-Anderson, Kelly M. / http://dx.doi.org/10.1021/bk-2019-1322.ch005
• Active Learning in the Large Lecture Hall Format / LaBrake, Cynthia / http://dx.doi.org/10.1021/bk-2019-1322.ch006
• Large-Scale, Team-Based Curriculum Transformation and Student Engagement in General Chemistry I and II / Lamont, Liana B., Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States; Stoll, Lindy K., Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States; Pesavento, Theresa M., Department of Academic Technology, University of Wisconsin-Madison, 1305 Linden Drive, Madison, Wisconsin 53706, United States; Bain, Rachel L., Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States; Landis, Clark R., Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States; Sibert, Edwin L., Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States / http://dx.doi.org/10.1021/bk-2019-1322.ch007
• Active Learning in Hybrid-Online General Chemistry / Miller, Dionne A. / http://dx.doi.org/10.1021/bk-2019-1322.ch008
• A Course Transformation to Support First-Year Chemistry Education for Engineering Students / Addison, Christopher J.; Núñez, José Rodríguez / http://dx.doi.org/10.1021/bk-2019-1322.ch009
• Flipped Classroom Learning Environments in General Chemistry: What Is the Impact on Student Performance in Organic Chemistry? / Eichler, Jack F., Department of Chemistry, University of California, Riverside, Riverside, California 92521, United States; Peeples, Junelyn, Department of Chemistry, University of California, Riverside, Riverside, California 92521, United States / http://dx.doi.org/10.1021/bk-2019-1322.ch010
• Editors' Biographies / http://dx.doi.org/10.1021/bk-2019-1322.ot001