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xii, 267 pages : illustrations (some color) ; [ca. 23-29] cm.
  • Overview. Molecular mechanisms and different favors of autophagy. Autophagy and cell fate. Cross-talk between autophagy and cell death pathways. Autophagy and cellular senescence in aging and pathophysiology. Autophagy, genome stability and cancer. Autophagy in Immunity and infection. Autophagy and regulation of immune response. Autophagy and inflammatory Disease. Autophagy and host response to invading pathogens. Autophagy in Nutrient Sensing and metabolism. Lipophagy: connecting autophagy and lipid metabolism. Functional interaction between autopahgy and ciliogenesis in nutrient sensing. Chaperone-mediated autophagy and energetic balance. Lysosome: A regulator of autophagy and cellular bioenergetics. Autophagy in Neural Homeostasis and Neurodegeneration. Mitophagy in aging and neurodegeneration. Autophagy in neural protein housekeeping: Different ways of taking the trash out. Central role of autophagy in the proteostasis network. Autophagy in synaptic structure and function: implications in brain injuries.
  • (source: Nielsen Book Data)9781498731904 20171218
Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.
(source: Nielsen Book Data)9781498731904 20171218
1 online resource (xiv, 361 pages) : illustrations (some color).
xxvii, 1022 pages : illustrations (some color) ; 29 cm
  • UNIT I: THE FOUNDATIONS OF MICROBIOLOGY 1. The Microbial World 2. Microbial Cell Structure and Function 3. Microbial Metabolism 4. Molecular Information Flow and Protein Processing UNIT II: MICROBIAL GROWTH AND REGULATION 5. Microbial Growth and Its Control 6. Microbial Regulatory Systems 7. Molecular Biology of Microbial Growth 8. Viruses and Their Replication UNIT III: GENOMICS AND GENETICS 9. Microbial Systems Biology 10. Viral Genomics 11. Genetics of Bacteria and Archaea 12. Biotechnology and Synthetic Biology UNIT IV: MICROBIAL EVOLUTION AND DIVERSITY 13. Microbial Evolution and Systematics 14. Metabolic Diversity of Microorganisms 15. Functional Diversity of Microorganisms 16. Diversity of Bacteria 17. Diversity of Archaea 18. Diversity of Microbial Eukarya UNIT V: MICROBIAL ECOLOGY AND ENVIRONMENTAL MICROBIOLOGY 19. Taking the Measure of Microbial Systems 20. Microbial Ecosystems 21. Nutrient Cycles in Nature 22. Microbiology of the Built Environment 23. Microbial Symbioses with Microbes, Plants, and Animals UNIT VI: MICROBE-HUMAN INTERACTIONS AND THE IMMUNE SYSTEM 24. Microbial Symbioses with Humans 25. Microbial Infection and Pathogenesis 26. Innate Immunity: Broadly Specific Host Defenses 27. Adaptive Immunity: Highly Specific Host Defenses 28. Clinical Microbiology and Immunology UNIT VII INFECTIOUS DISEASES AND THEIR TRANSMISSION 29. Epidemiology 30. Person-to-Person Bacterial and Viral Diseases 31. Vectorborne and Soilborne Bacterial and Viral Diseases 32. Foodborne and Waterborne Bacterial and Viral Diseases 33. Eukaryotic Pathogens: Fungi, Protozoa, and Helminths.
  • (source: Nielsen Book Data)9780134261928 20171121
  • Machine generated contents note: UNIT 1 Foundations of Microbiology
  • 1. Microbial World
  • Microbiologynow Microorganisms, Our Constant Companions
  • I. Exploring the Microbial World
  • 1.1. Microorganisms, Tiny Titans of the Earth
  • 1.2. Structure and Activities of Microbial Cells
  • 1.3. Microorganisms and the Biosphere
  • 1.4. Impact of Microorganisms on Human Society
  • II. Microscopy and the Origins of Microbiology
  • 1.5. Light Microscopy and the Discovery of Microorganisms
  • 1.6. Improving Contrast in Light Microscopy
  • 1.7. Imaging Cells in Three Dimensions
  • 1.8. Probing Cell Structure: Electron Microscopy
  • III. Microbial Cultivation Expands the Horizon of Microbiology
  • 1.9. Pasteur and Spontaneous Generation
  • 1.10. Koch, Infectious Diseases, and Pure Cultures
  • 1.11. Discovery of Microbial Diversity
  • IV. Molecular Biology and the Unity and Diversity of Life
  • 1.12. Molecular Basis of Life
  • 1.13. Woese and the Tree of Life
  • 1.14. Introduction to Microbial Life
  • 2. Microbial Cell Structure and Function
  • Microbiologynow The Archaellum: Motility for the Archaea
  • I. Cells of Bacteria and Archaea
  • 2.1. Cell Morphology
  • 2.2. Small World
  • II. Cell Membrane and Wall
  • 2.3. Cytoplasmic Membrane
  • 2.4. Bacterial Cell Walls: Peptidoglycan
  • 2.5. LPS: The Outer Membrane
  • 2.6. Archaeal Cell Walls
  • III. Cell Surface Structures and Inclusions
  • 2.7. Cell Surface Structures
  • 2.8. Cell Inclusions
  • 2.9. Gas Vesicles
  • 2.10. Endospores
  • IV. Cell Locomotion
  • 2.11. Flagella, Archaella, and Swimming Motility
  • 2.12. Gliding Motility
  • 2.13. Chemotaxis and Other Taxes
  • V. Eukaryotic Microbial Cells
  • 2.14. Nucleus and Cell Division
  • 2.15. Mitochondria, Hydrogenosomes, and Chloroplasts
  • 2.16. Other Eukaryotic Cell Structures
  • Explore The Microbial World Tiny Cells
  • 3. Microbial Metabolism
  • Microbiologynow Sugars and Sweets: Archaea Do It Their Way
  • I. Microbial Nutrients and Nutrient Uptake
  • 3.1. Feeding the Microbe: Cell Nutrition
  • 3.2. Transporting Nutrients into the Cell
  • II. Energetics, Enzymes, and Redox
  • 3.3. Energy Classes of Microorganisms
  • 3.4. Principles of Bioenergetics
  • 3.5. Catalysis and Enzymes
  • 3.6. Electron Donors and Acceptors
  • 3.7. Energy-Rich Compounds
  • III. Catabolism: Fermentation and Respiration
  • 3.8. Glycolysis and Fermentation
  • 3.9. Respiration: Citric Acid and Glyoxylate Cycles
  • 3.10. Respiration: Electron Carriers
  • 3.11. Electron Transport and the Proton Motive Force
  • 3.12. Options for Energy Conservation
  • IV. Biosyntheses
  • 3.13. Sugars and Polysaccharides
  • 3.14. Amino Acids and Nucleotides
  • 3.15. Fatty Acids and Lipids
  • 4. Molecular Information Flow and Protein Processing
  • Microbiologynow Synthesis of Jumbo Proteins: Secretion of Halomucin
  • I. Molecular Biology and Genetic Elements
  • 4.1. DNA and Genetic Information Flow
  • 4.2. Genetic Elements: Chromosomes and Plasmids
  • II. Copying the Genetic Blueprint: DNA Replication
  • 4.3. Templates, Enzymes, and the Replication Fork
  • 4.4. Bidirectional Replication, the Replisome, and Proofreading
  • III. RNA Synthesis: Transcription
  • 4.5. Transcription in Bacteria
  • 4.6. Transcription in Archaea and Eukarya
  • IV. Protein Synthesis: Translation
  • 4.7. Amino Acids, Polypeptides, and Proteins
  • 4.8. Transfer RNA
  • 4.9. Translation and the Genetic Code
  • 4.10. Mechanism of Protein Synthesis
  • V. Protein Processing, Secretion, and Targeting
  • 4.11. Assisted Protein Folding and Chaperones
  • 4.12. Protein Secretion: The Sec and Tat Systems
  • 4.13. Protein Secretion: Gram-Negative Systems
  • UNIT 2 Microbial Growth and Regulation
  • 5. Microbial Growth and Its Control
  • Microbiologynow Picking Apart a Microbial Consortium
  • I. Cell Division and Population Growth
  • 5.1. Binary Fission, Budding, and Biofilms
  • 5.2. Quantitative Aspects of Microbial Growth
  • 5.3. Microbial Growth Cycle
  • 5.4. Continuous Culture
  • II. Culturing Microbes and Measuring Their Growth
  • 5.5. Growth Media and Laboratory Culture
  • 5.6. Microscopic Counts of Microbial Cell Numbers
  • 5.7. Viable Counting of Microbial Cell Numbers
  • 5.8. Turbidimetric Measures of Microbial Cell Numbers
  • III. Environmental Effects on Growth: Temperature
  • 5.9. Temperature Classes of Microorganisms
  • 5.10. Microbial Life in the Cold
  • 5.11. Microbial Life at High Temperatures
  • IV. Environmental Effects on Growth: pH, Osmolarity, and Oxygen
  • 5.12. Effects of pH on Microbial Growth
  • 5.13. Osmolarity and Microbial Growth
  • 5.14. Oxygen and Microbial Growth
  • V. Controlling Microbial Growth
  • 5.15. General Principles and Growth Control by Heat
  • 5.16. Other Physical Control Methods: Radiation and Filtration
  • 5.17. Chemical Control of Microbial Growth
  • 6. Microbial Regulatory Systems
  • Microbiologynow Microbial Hunter: Pseudomonas aeruginosa Senses and Scavenges Nutrients from Damaged Tissues
  • I. DNA-Binding Proteins and Transcriptional Regulation
  • 6.1. DNA-Binding Proteins
  • 6.2. Negative Control: Repression and Induction
  • 6.3. Positive Control: Activation
  • 6.4. Global Control and the lac Operon
  • 6.5. Transcription Controls in Archaea
  • II. Sensing and Signal Transduction
  • 6.6. Two-Component Regulatory Systems
  • 6.7. Regulation of Chemotaxis
  • 6.8. Quorum Sensing
  • 6.9. Stringent Response
  • 6.10. Other Global Networks
  • III. RNA-Based Regulation
  • 6.11. Regulatory RNAs
  • 6.12. Riboswitches
  • 6.13. Attenuation
  • IV. Regulation of Enzymes and Other Proteins
  • 6.14. Feedback Inhibition
  • 6.15. Post-Translational Regulation
  • 7. Molecular Biology of Microbial Growth
  • Microbiologynow Explosive Cell Death Promotes Biofilm Formation
  • I. Bacterial Cell Division
  • 7.1. Visualizing Molecular Growth
  • 7.2. Chromosome Replication and Segregation
  • 7.3. Cell Division and Fts Proteins
  • 7.4. MreB and Cell Morphology
  • 7.5. Peptidoglycan Biosynthesis
  • II. Regulation of Development in Model Bacteria
  • 7.6. Regulation of Endospore Formation
  • 7.7. Caulobacter Differentiation
  • 7.8. Heterocyst Formation in Anabaena
  • 7.9. Biofilm Formation
  • III. Antibiotics and Microbial Growth
  • 7.10. Antibiotic Targets and Antibiotic Resistance
  • 7.11. Persistence and Dormancy
  • 8. Viruses and Their Replication
  • Microbiologynow Virophages: Viruses That Parasitize Other Viruses
  • I. Nature of Viruses
  • 8.1. What Is a Virus-- 8.2. Structure of the Virion
  • 8.3. Overview of the Virus Life Cycle
  • 8.4. Culturing, Detecting, and Counting Viruses
  • II. Viral Replication Cycle
  • 8.5. Attachment and Entry of Bacteriophage T4
  • 8.6. Replication of Bacteriophage T4
  • 8.7. Temperate Bacteriophages and Lysogeny
  • 8.8. Overview of Animal Virus Infection
  • UNIT 3 Genomics and Genetics
  • 9. Microbial Systems Biology
  • Microbiologynow DNA Sequencing in the Palm of Your Hand
  • I. Genomics
  • 9.1. Introduction to Genomics
  • 9.2. Sequencing and Annotating Genomes
  • 9.3. Genome Size and Gene Content in Bacteria and Archaea
  • 9.4. Organelle and Eukaryotic Microbial Genomes
  • II. Evolution of Genomes
  • 9.5. Gene Families, Duplications, and Deletions
  • 9.6. Horizontal Gene Transfer and the Mobilome
  • 9.7. Core Genome Versus Pan Genome
  • III. Functional Omics
  • 9.8. Metagenomics
  • 9.9. Gene Chips and Transcriptomics
  • 9.10. Proteomics and the Interactome
  • 9.11. Metabolomics
  • IV. Utility of Systems Biology
  • 9.12. Single-Cell Genomics
  • 9.13. Integrating Mycobacterium tuberculosis Omics
  • 9.14. Systems Biology and Human Health
  • 10. Viral Genomics, Diversity, and Ecology
  • Microbiologynow Viral Imaging to the Rescue: Structural Blueprint of Zika
  • I. Viral Genomes and Evolution
  • 10.1. Size and Structure of Viral Genomes
  • 10.2. Viral Evolution
  • II. DNA Viruses
  • 10.3. Single-Stranded DNA Bacteriophages: φ[×]174 and M13
  • 10.4. Double-Stranded DNA Bacteriophages: T7 and Mu
  • 10.5. Viruses of Archaea
  • 10.6. Uniquely Replicating DNA Animal Viruses
  • 10.7. DNA Tumor Viruses
  • III. Viruses with RNA Genomes
  • 10.8. Positive-Strand RNA Viruses
  • 10.9. Negative-Strand RNA Animal Viruses
  • 10.10. Double-Stranded RNA Viruses
  • 10.11. Viruses That Use Reverse Transcriptase
  • IV. Viral Ecology
  • 10.12. Bacterial and Archael Virosphere
  • 10.13. Viral Defense Mechanisms of Bacteria and Archaea
  • 10.14. Human Virome
  • V. Subviral Agents
  • 10.15. Viroids
  • 10.16. Prions
  • 11. Genetics of Bacteria and Archaea
  • Microbiologynow Killing and Stealing: DNA Uptake by the Predator Vibrio cholerae
  • I. Mutation
  • 11.1. Mutations and Mutants
  • 11.2. Molecular Basis of Mutation
  • 11.3. Reversions and Mutation Rates
  • 11.4. Mutagenesis
  • II. Gene Transfer in Bacteria
  • 11.5. Genetic Recombination
  • 11.6. Transformation
  • 11.7. Transduction
  • 11.8. Conjugation
  • 11.9. Formation of Hfr Strains and Chromosome Mobilization
  • III. Gene Transfer in Archaea and Other Genetic Events
  • 11.10. Horizontal Gene Transfer in Archaea
  • 11.11. Mobile DNA: Transposable Elements
  • 11.12. Preserving Genomic Integrity: CRISPR Interference
  • 12. Biotechnology and Synthetic Biology
  • Microbiologynow Creation of a New Life Form: Design of a Minimal Cell
  • I. Tools of the Genetic Engineer
  • 12.1. Manipulating DNA: PCR and Nucleic Acid Hybridization --
  • Contents note continued: 22.3. Bioremediation of Uranium-Contaminated Environments
  • 22.4. Bioremediation of Organic Pollutants: Hydrocarbons
  • 22.5. Bioremediation of Organic Pollutants: Pesticides and Plastics
  • III. Wastewater and Drinking Water Treatment
  • 22.6. Primary and Secondary Wastewater Treatment
  • 22.7. Advanced Wastewater Treatment
  • 22.8. Drinking Water Purification and Stabilization
  • 22.9. Water Distribution Systems
  • IV. Indoor Microbiology and Microbially Influenced Corrosion
  • 22.10. Microbiology of Homes and Public Spaces
  • 22.11. Microbially Influenced Corrosion of Metals
  • 22.12. Biodeterioration of Stone and Concrete
  • 23. Microbial Symbioses with Microbes, Plants, and Animals
  • Microbiologynow The Inner Life of Bees
  • I. Symbioses between Microorganisms
  • 23.1. Lichens
  • 23.2. "Chlorochromatium aggregatum"
  • II. Plants as Microbial Habitats
  • 23.3. Legume--Root Nodule Symbiosis
  • 23.4. Mycorrhizae
  • 23.5. Agrobacterium and Crown Gall Disease
  • III. Insects as Microbial Habitats
  • 23.6. Heritable Symbionts of Insects
  • 23.7. Termites
  • IV. Other Invertebrates as Microbial Habitats
  • 23.8. Hawaiian Bobtail Squid
  • 23.9. Marine Invertebrates at Hydrothermal Vents and Cold Seeps
  • 23.10. Entomopathogenic Nematodes
  • 23.11. Reef-Building Corals
  • V. Mammalian Gut Systems as Microbial Habitats
  • 23.12. Alternative Mammalian Gut Systems
  • 23.13. Rumen and Ruminant Animals
  • Explore The Microbial World The Multiple Microbial Symbionts of Fungus-Cultivating Ants
  • UNIT 6 Microbe--Human Interactions and the Immune System
  • 24. Microbial Symbioses with Humans
  • Microbiologynow Frozen in Time: The Iceman Microbiome
  • I. Structure and Function of the Healthy Adult Human Microbiome
  • 24.1. Overview of the Human Microbiome
  • 24.2. Gastrointestinal Microbiota
  • 24.3. Oral Cavity and Airways
  • 24.4. Urogenital Tracts and Their Microbes
  • 24.5. Skin and Its Microbes
  • II. From Birth to Death: Development of the Human Microbiome
  • 24.6. Human Study Groups and Animal Models
  • 24.7. Colonization, Succession, and Stability of the Gut Microbiota
  • III. Disorders Attributed to the Human Microbiome
  • 24.8. Disorders Attributed to the Gut Microbiota
  • 24.9. Disorders Attributed to the Oral, Skin, and Vaginal Microbiota
  • IV. Modulation of the Human Microbiome
  • 24.10. Antibiotics and the Human Microbiome
  • 24.11. Probiotics and Prebiotics
  • Explore The Microbial World The Gut--Brain Axis
  • 25. Microbial Infection and Pathogenesis
  • Microbiologynow The Microbial Community That Thrives on Your Teeth
  • I. Human--Microbial Interactions
  • 25.1. Microbial Adherence
  • 25.2. Colonization and Invasion
  • 25.3. Pathogenicity, Virulence, and Attenuation
  • 25.4. Genetics of Virulence and the Compromised Host
  • II. Enzymes and Toxins of Pathogenesis
  • 25.5. Enzymes as Virulence Factors
  • 25.6. AB-Type Exotoxins
  • 25.7. Cytolytic and Superantigen Exotoxins
  • 25.8. Endotoxins
  • 26. Innate Immunity: Broadly Specific Host Defenses
  • Microbiologynow Rehabilitating a Much-Maligned Peptide: Amyloid-β
  • I. Fundamentals of Host Defense
  • 26.1. Basic Properties of the Immune System
  • 26.2. Barriers to Pathogen Invasion
  • II. Cells and Organs of the Immune System
  • 26.3. Blood and Lymphatic Systems
  • 26.4. Leukocyte Production and Diversity
  • III. Phagocyte Response Mechanisms
  • 26.5. Pathogen Challenge and Phagocyte Recruitment
  • 26.6. Pathogen Recognition and Phagocyte Signal Transduction
  • 26.7. Phagocytosis and Phagocyte Inhibition
  • IV. Other Innate Host Defenses
  • 26.8. Inflammation and Fever
  • 26.9. Complement System
  • 26.10. Innate Defenses against Viruses
  • Explore The Microbial World Drosophila Toll Receptors---An Ancient Response to Infections
  • 27. Adaptive Immunity: Highly Specific Host Defenses
  • Microbiologynow Got (Raw) MilkThe Role of Unprocessed Cow's Milk in Protecting against Allergy and Asthma
  • I. Principles of Adaptive Immunity
  • 27.1. Specificity, Memory, Selection Processes, and Tolerance
  • 27.2. Immunogens and Classes of Immunity
  • II. Antibodies
  • 27.3. Antibody Production and Structural Diversity
  • 27.4. Antigen Binding and the Genetics of Antibody Diversity
  • III. Major Histocompatibility Complex (MHC)
  • 27.5. MHC Proteins and Their Functions
  • 27.6. MHC Polymorphism, Polygeny, and Peptide Binding
  • IV. T Cells and Their Receptors
  • 27.7. T Cell Receptors: Proteins, Genes, and Diversity
  • 27.8. T Cell Diversity
  • V. Immune Disorders and Deficiencies
  • 27.9. Allergy, Hypersensitivity, and Autoimmunity
  • 27.10. Superantigens and Immunodeficiency
  • 28. Clinical Microbiology and Immunology
  • Microbiologynow Bacteriophages: Tiny Allies in the Fight against Antibiotic-Resistant Bacteria
  • I. Clinical Microbiology Setting
  • 28.1. Safety in the Microbiology Laboratory
  • 28.2. Healthcare-Associated Infections
  • II. Isolating and Characterizing Infectious Microorganisms
  • 28.3. Workflow in the Clinical Laboratory
  • 28.4. Choosing the Right Treatment
  • III. Immunological and Molecular Tools for Disease Diagnosis
  • 28.5. Immunoassays and Disease
  • 28.6. Precipitation, Agglutination, and Immunofluorescence
  • 28.7. Enzyme Immunoassays, Rapid Tests, and Immunoblots
  • 28.8. Nucleic Acid--Based Clinical Assays
  • IV. Prevention and Treatment of Infectious Diseases
  • 28.9. Vaccination
  • 28.10. Antibacterial Drugs
  • 28.11. Antimicrobial Drugs That Target Nonbacterial Pathogens
  • 28.12. Antimicrobial Drug Resistance and New Treatment Strategies
  • Explore The Microbial World MRSA---A Formidable Clinical Challenge
  • UNIT 7 Infectious Diseases and Their Transmission
  • 29. Epidemiology
  • Microbiologynow A Mysterious New Disease Outbreak
  • I. Principles of Epidemiology
  • 29.1. Language of Epidemiology
  • 29.2. Host Community
  • 29.3. Infectious Disease Transmission and Reservoirs
  • 29.4. Characteristics of Disease Epidemics
  • II. Epidemiology and Public Health
  • 29.5. Public Health and Infectious Disease
  • 29.6. Global Health Comparisons
  • III. Emerging Infectious Diseases, Pandemics, and Other Threats
  • 29.7. Emerging and Reemerging Infectious Diseases
  • 29.8. Examples of Pandemics: HIV/AIDS, Cholera, and Influenza
  • 29.9. Public Health Threats from Microbial Weapons
  • Explore The Microbial World Textbook Epidemiology: The SARS Epidemic
  • 30. Person-to-Person Bacterial and Viral Diseases
  • Microbiologynow A New Weapon against AIDS-- I. Airborne Bacterial Diseases
  • 30.1. Airborne Pathogens
  • 30.2. Streptococcal Syndromes
  • 30.3. Diphtheria and Pertussis
  • 30.4. Tuberculosis and Leprosy
  • 30.5. Meningitis and Meningococcemia
  • II. Airborne Viral Diseases
  • 30.6. MMR and Varicella-Zoster Infections
  • 30.7. Common Cold
  • 30.8. Influenza
  • III. Direct-Contact Bacterial and Viral Diseases
  • 30.9. Staphylococcus aureus Infections
  • 30.10. Helicobacter pylori and Gastric Diseases
  • 30.11. Hepatitis
  • 30.12. Ebola: A Deadly Threat
  • IV. Sexually Transmitted Infections
  • 30.13. Gonorrhea and Syphilis
  • 30.14. Chlamydia, Herpes, and Human Papillomavirus
  • 30.15. HIV/AIDS
  • 31. Vectorborne and Soilborne Bacterial and Viral Diseases
  • Microbiologynow A New Look at Rabies Vaccines
  • I. Animal-Transmitted Viral Diseases
  • 31.1. Rabies Virus and Rabies
  • 31.2. Hantavirus and Hantavirus Syndromes
  • II. Arthropod-Transmitted Bacterial and Viral Diseases
  • 31.3. Rickettsial Diseases
  • 31.4. Lyme Disease and Borrelia
  • 31.5. Yellow Fever, Dengue Fever, Chikungunya, and Zika
  • 31.6. West Nile Fever
  • 31.7. Plague
  • III. Soilborne Bacterial Diseases
  • 31.8. Anthrax
  • 31.9. Tetanus and Gas Gangrene
  • 32. Waterborne and Foodborne Bacterial and Viral Diseases
  • Microbiologynow The Classic Botulism Scenario
  • I. Water as a Disease Vehicle
  • 32.1. Agents and Sources of Waterborne Diseases
  • 32.2. Public Health and Water Quality
  • II. Waterborne Diseases
  • 32.3. Vibrio cholerae and Cholera
  • 32.4. Legionellosis
  • 32.5. Typhoid Fever and Norovirus Illness
  • III. Food as a Disease Vehicle
  • 32.6. Food Spoilage and Food Preservation
  • 32.7. Foodborne Disease and Food Epidemiology
  • IV. Food Poisoning
  • 32.8. Staphylococcal Food Poisoning
  • 32.9. Clostridial Food Poisoning
  • V. Food Infection
  • 32.10. Salmonellosis
  • 32.11. Pathogenic Escherichia coli
  • 32.12. Campylobacter
  • 32.13. Listeriosis
  • 32.14. Other Foodborne Infectious Diseases
  • 33. Eukaryotic Pathogens: Fungi, Protozoa, and Helminths
  • Microbiologynow Environmental Change and Parasitic Diseases in the Amazon
  • I. Fungal Infections
  • 33.1. Pathogenic Fungi and Classes of Infection
  • 33.2. Fungal Diseases: Mycoses
  • II. Visceral Parasitic Infections
  • 33.3. Amoebae and Ciliates: Entamoeba, Naegleria, and Balantidium
  • 33.4. Other Visceral Parasites: Giardia, Trichomonas, Cryptosporidium, Toxoplasma, and Cyclospora
  • III. Blood and Tissue Parasitic Infections
  • 33.5. Plasmodium and Malaria
  • 33.6. Leishmaniasis, Trypanosomiasis, and Chagas Disease
  • 33.7. Parasitic Helminths: Schistosomiasis and Filariases.
For courses in General Microbiology. A streamlined approach to master microbiologyBrock Biology of Microorganisms is the leading majors microbiology text on the market. It sets the standard for impeccable scholarship, accuracy, and strong coverage of ecology, evolution, and metabolism. The 15th edition seamlessly integrates the most current science, paying particular attention to molecular biology and the genomic revolution. It introduces a flexible, more streamlined organization with a consistent level of detail and comprehensive art program. Brock Biology of Microorganisms helps students quickly master concepts, both in and outside the classroom, through personalized learning, engaging activities to improve problem solving skills, and superior art and animations with Mastering (TM) Microbiology. Also available with Mastering Microbiology.Mastering (TM) Microbiology is an online homework, tutorial, and assessment product designed to improve results by helping students quickly master concepts. Students benefit from self-paced tutorials that feature personalized wrong-answer feedback and hints that emulate the office-hour experience and help keep students on track. With a wide range of interactive, engaging, and assignable activities, students are encouraged to actively learn and retain tough course concepts.Students, if interested in purchasing this title with Mastering Microbiology, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. Note: You are purchasing a standalone product; Mastering (TM) Microbiology does not come packaged with this content. Students, if interested in purchasing this title with Mastering Microbiology, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and Mastering Microbiology, search for: 0134268660 / 9780134268668 Brock Biology of Microorganisms Plus Mastering Microbiology with eText -- Access Card Package, 15/e Package consists of:0134261925 / 9780134261928 Brock Biology of Microorganisms0134603974 / 9780134603971 Mastering Microbiology with Pearson eText -- Standalone Access Card -- for Brock Biology of Microorganisms, 15/e MasteringMicrobiology should only be purchased when required by an instructor.
(source: Nielsen Book Data)9780134261928 20171121
Science Library (Li and Ma)
xxx, 555, A-3, B-3, C-2, D-2, G-17, I-21 pages ; 28 cm
  • 1. The Main Themes of Microbiology2. The Chemistry of Biology3. Tools of the Laboratory: Methods of Studying Microorganisms4. A Survey of Prokaryotic Cells and Microorganisms5. A Survey of Eukaryotic Cells and Microorganisms6. An Introduction to Viruses7. Microbial Nutrition, Ecology, and Growth8. An Introduction to Microbial Metabolism: The Chemical Crossroads of Life9. Microbial Genetics10. Genetic Engineering: A Revolution in Molecular Biology11. Physical and Chemical Agents for Microbial Control12. Drugs, Microbes, Host--The Elements of Chemotherapy13. Microbe-Human Interactions: Infection, Disease, and Epidemiology14. An Introduction to Host Defenses and Innate Immunities15. Adaptive, Specific Immunity and Immunization16. Disorders in Immunity17. Procedures for Identifying Pathogens and Diagnosing Infections.
  • (source: Nielsen Book Data)9781259916038 20171106
Foundations in Microbiology is an allied health microbiology text with a taxonomic approach to the disease chapters. It offers an engaging and accessible writing style through the use of case studies and analogies to thoroughly explain difficult microbiology concepts.We were so excited to offer a robust learning program with student-focused learning activities, allowing the students to manage their learning while you easily manage their assessment. Revised art and updated photos help concepts stand out. Detailed reports show how your assignments measure various learning objectives from the book (or input your own!), levels of Bloom's Taxonomy or other categories, and how your students are doing. The Talaro Learning Users who purchase Connect receive access to a full online eBook version of the textbook, including SmartBook! New to SmartBook with this edition are learning resources to aid student understanding of content utilizing a variety of learning tools.
(source: Nielsen Book Data)9781259916038 20171106
Science Library (Li and Ma)
1 online resource.
xvii, 552, A3, B4, C2, G6, I4 pages : illustrations (chiefly color) ; 28 cm
This popular lab manual that for years has taught students the basics of working in a lab and how to safely handle microorganisms, has been completely redesigned and updated. All labs have been expanded and reorganized to fit neatly into new sections of the lab, such as "Fungi", "Viruses", or "Biotechnology", and are presented from easiest to most challenging. New introductions for each section provide the appropriate context for the labs and connects the lab concepts to the core text, Fundamentals of Microbiology, Eleventh Edition. The most exciting update are the NEW videos available with the Lab Manual that teach common lab skills that tie to the labs in the manual. Students will clearly see how to work safely in the lab setting, how to use operating equipment, how to swab cultures, and many more lab skills. New photos and micrograph examples and new exercises and assessments only further enhance the eleventh edition of Laboratory Fundamentals of Microbiology, making it the easy choice for microbiology lab courses.
(source: Nielsen Book Data)9781284100976 20171030
Science Library (Li and Ma)
xxii, 292 pages, 10 pages of plates : illustrations (some color) ; 26 cm
  • Bioaerosols, sampling and characterization
  • Sources and transport of microbial aerosols
  • Impacts of microbial aerosols on atmospheric processes
  • Impacts of bioaerosols on human health and environment.
An introduction to the microbiology of bioaerosols and their impact on the world in which we live The microbiology of aerosols is an emerging field of research that lies at the interface of a variety of scientific and health-related disciplines. This eye-opening book synthesizes the current knowledge about microorganisms bacteria, archaea, fungi, viruses that are aloft in the atmosphere. The book is written collaboratively by an interdisciplinary and international panel of experts and carefully edited to provide a high-level overview of the emerging field of aerobiology. Four sections within Microbiology of Aerosols present the classical and online methods used for sampling and characterizing airborne microorganisms, their emission sources and short- to long-distance dispersal, their influence on atmospheric processes and clouds, and their consequences for human health and agro-ecosystems. Practical considerations are also discussed, including sampling techniques, an overview of the quantification and characterization of bioaerosols, transport of bioaerosols, and a summary of ongoing research opportunities in the field. Comprehensive in scope, the book: Explores this new field that is applicable to many disparate disciplinesCovers the emission of bioaerosols to their deposit, covering both quantitative and qualitative aspectsProvides insights into social and environmental effects of the presence of bioaerosols in the atmosphereDetails the impact of bioaerosols on human health, animal and plant health, and on physical and chemical atmospheric processes Written by authors internationally recognized for their work on biological aerosols and originating from a variety of scientific fields collaborated on, Microbiology of Aerosols is an excellent resource for researchers and graduate or PhD students interested in atmospheric sciences or microbiology.
(source: Nielsen Book Data)9781119132288 20171211
Science Library (Li and Ma)
1 online resource (xviii, 300 pages) : illustrations.
  • SECTION 1: ANTI-GAL BACKGROUND 1. Anti-Gal in humans and its antigen the α-gal epitope 2. Why do we produce anti-Gal: Evolutionary appearance of anti-Gal in Old World primates 3. Anti-Gal comprises most of anti-blood group B antibodies: Landsteiner's enigma 4. Anti-Gal interaction with Trypanosoma, Leishmania and Plasmodium parasites 5. Anti-Gal B cells are tolerized by α-gal epitopes in the absence of T cell help SECTION 2: ANTI-GAL AS FOE 6. Anti-Gal and other immune barriers in xenotransplantation 7. Anti-Gal IgE mediates allergies to red meat 8. Anti-Gal and autoimmunity SECTION 3: ANTI-GAL AS FRIEND 9. Anti-Gal mediated amplification of viral vaccine efficacy 10. Cancer immunotherapy by anti-Gal mediated in situ conversion of tumors into autologous vaccines 11. Anti-Gal as cancer cell destroying antibody and as antibiotics targeted by α-gal bi-functional molecules 12. Acceleration of wound and burn healing by anti-Gal/α-gal nanoparticles interaction SECTION 4: FUTURE HYPOTHETICAL DIRECTIONS 13. Anti-Gal and anti-non gal antibodies in regeneration of extracellular matrix (ECM) bio-implants in humans 14. Post infarction regeneration of ischemic myocardium by intramyocardial injection of α-gal nanoparticles 15. Regeneration of injured spinal cord and peripheral nerves by α-gal nanoparticles 16. Inhalation of α-gal/sialic acid liposomes for decreasing influenza virus infection.
  • (source: Nielsen Book Data)9780128133620 20171017
The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.
(source: Nielsen Book Data)9780128133620 20171017
1 online resource (599 p.) : ill., ports.
"Pasteurization, penicillin, Koch's postulates, and gene coding. These discoveries and inventions are vital yet commonplace in modern life, but were radical when first introduced to the public and academia. In this book, the life and times of leading pioneers in microbiology are discussed in vivid detail, focusing on the background of each discovery and the process in which they were developed — sometimes by accident or sheer providence."--Publisher's website.
1 online resource.
  • 1. Introductory Text And Impact of Foodborne Disease2. Characteristics of the Pathogen3. Molecular Biology of the Pathogen4. Methodological Aspects5. Food safety aspects6. Prevention and Control7. Case and Outbreak Studies.
  • (source: Nielsen Book Data)9780128096710 20171017
Staphylococcus aureus provides information on food borne outbreaks of disease and their impact on human health. It is for anyone interested in the features of the pathogen, and its food safety aspects, as well as its prevalence and possible control and eradication options. This is a practical reference for those in the food industry, but also includes some theoretical information useful for advising. The book introduces detailed features and molecular biology of the pathogen, as well as selective methods of detection, prevention and eradication essential for research. It covers methicillin-resistant staphylococcus aureus for food related industries, information on genetic lineages, cell wall components, cell division machinery, molecular characterization, and capillary electrophoresis for detecting and characterizing staphylococcus aureus.
(source: Nielsen Book Data)9780128096710 20171017
1 online resource.
  • 1. Introduction 2. The Complement Proteins C1q and the Collectins Serine proteases C3 Family Terminal Pathway Components Regulations of Complement Activation (RCA) Cell Surface Receptors Miscellaneous Complement Components.
  • (source: Nielsen Book Data)9780128104200 20171211
The Complement FactsBook, Second Edition, provides in-depth insights and an overview of the components of the complement system. This new edition highlights the use of newly recommended complement nomenclature, covering new pathways and proteins and adding information on mouse homologs. It is a completely revised and updated edition containing entries on all components of the complement system, and is an excellent source of one-stop shopping for complement information and references. It is the most convenient compilation of biochemical, biological and molecular biology for complementologists and those new in the field. This new edition is expanded to include relevant updates and topics that have evolved since the last edition was published, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families.
(source: Nielsen Book Data)9780128104200 20171211
xii, 346 pages ; 27 cm.
  • PART-I: DESCRIPTION OF ACETIC ACID BACTERIA Systematics of Acetic Acid Bacteria Taweesak Malimas, Huong Thi Lan Vu, Yuki Muramatsu, Pattaraporn Yukphan, Somboon Tanasupawat and Yuzo Yamada Comparative Genomics of Acetobacter and other Acetic Acid Bacteria Jure Skraban and Janja Trcek Physiology and Biochemistry of Acetic Acid Bacteria Birce Mercanoglu Taban and Natsaran Saichana Acetic Acid Bacteria Strategies Contributing to Acetic Acid Resistance During Oxidative Fermentation Cristina Andres-Barrao and Francois Barja Exopolysaccharide Production of Acetic Acid Bacteria Seval Dagbagli and Yekta Goksungur Improvements of Acetic Acid Bacterial Strains: Thermotolerant Properties of Acetic Acid Bacteria and Genetic Modification for Strain Development Natsaran Saichana Identification Techniques of Acetic Acid Bacteria: Comparison between MALDI-TOF MS and Molecular Biology Techniques Cristina Andres-Barrao, Francois Barja, Ruben Ortega Perez, Marie-Louise Chappuis, Sarah Braito, Ana Hospital Bravo Preservation of Acetic Acid Bacteria Luciana De Vero, Maria Gullo and Paolo Giudici PART-II: IMPORTANCE OF ACETIC ACID BACTERIA IN FOOD INDUSTRY Microbiology of Fermented Foods Ilkin Yucel Sengun and Michael P. Doyle Vinegars Paolo Giudici, Luciana De Vero, Maria Gullo Impact of acetic acid bacteria on cocoa fermentation Yasmine Hamdouche, Corinne Teyssier and Didier Montet Detrimental Effects of AAB in Foods Maria Jose Valera, Maria Jesus Torija and Albert Mas Beneficial Effects of Acetic Acid Bacteria and Their Food Products Seniz Karabiyikli and Ilkin Yucel Sengun.
  • (source: Nielsen Book Data)9781498763691 20170703
This book, written by leading international authorities in the field, covers all the basic and applied aspects of acetic acid bacteria. It describes the importance of acetic acid bacteria in food industry by giving information on the microbiological properties of fermented foods as well as production procedures. Special attention is given to vinegar and cocoa, which are the most familiar and extensively used industrial applications of acetic acid bacteria. This book is an essential reference to all scientists, technologists, engineers, students and all those working in the field of food science and technology.
(source: Nielsen Book Data)9781498763691 20170703
Science Library (Li and Ma)
1 online resource ( x, 342 pages) : illustrations (some color).
  • 1.Physico-chemical boundaries of life.- 2.Microbial diversity in deep hypersaline anoxic basins.- 3.Microbial speciation in the geothermal ecosystem.- 4.Bacterial adaptation to hot and dry deserts.- 5.Extremophiles in Antarctica: Life at low temperatures.- 6.Anhydrobiotic rock-inhabiting cyanobacteria: Potential for astrobiology and biotechnology.- 7.Psychrophilic microorganisms as important source for biotechnological processes.- 8.Halophilic microorganisms from man-made and natural hypersaline environments: Physiology, ecology, and biotechnological potential.- 9.Applications of extremophiles in astrobiology: Habitability and life detection strategies.- 10.Extremophiles in spacecraft assembly clean rooms.- 11.The Extreme Biology of Meteorites: Their Role in Understanding the Origin and Distribution of Life on Earth and in the Universe.
  • (source: Nielsen Book Data)9783319483252 20170502
This entirely updated second edition provides an overview on the biology, ecology and biodiversity of extremophiles. Unusual and less explored ecosystems inhabited by extremophiles such as marine hypersaline deeps, extreme cold, desert sands, and man-made clean rooms for spacecraft assembly are presented. An additional focus is put on the role of these highly specialized microorganism in applied research fields, ranging from biotechnology and nanotechnology to astrobiology. Examples such as novel psychrophilic enzymes, compounds from halophiles, and detection strategies for potential extraterrestrial life forms are discussed in detail. The book addresses researchers and advanced students in the fields of microbiology, microbial ecology and biotechnology.
(source: Nielsen Book Data)9783319483252 20170502
EBSCOhost Access limited to 1 user
1 online resource.
  • About the Editors; Part I: Role of Soil Microbe Interaction; 1: Plant Beneficial Rhizospheric Microbes (PBRMs): Prospects for Increasing Productivity and Sustaining the Resilience of Soil Fertility; 1.1 Introduction; 1.2 Rhizosphere Deposits and Priming Effect; 1.3 Plant Beneficial Rhizospheric Microbes (PBRMs); 1.3.1 Rhizospheric Microbes and Nutrient Acquisition; 1.3.2 Biocontrol Activities of Plant Beneficial Rhizospheric Microbes; 1.3.3 Rhizospheric Microbes in Plant Stress Resistance; 1.3.4 Rhizospheric Microbes and Crop Growth
  • 1.3.5 Role of Rhizospheric Microbes in Soil Fertility and Sustainability1.4 Future Prospects; 1.5 Conclusions; References; 2: Rhizosphere Microorganisms Towards Soil Sustainability and Nutrient Acquisition; 2.1 Introduction; 2.2 Why Soil Sustainability Is So Important?; 2.3 The Rhizosphere: A Hot Spot for Microbial Activities; 2.4 Role of Rhizosphere Microorganisms in Soil Sustainability and Nutrient Acquisition; 2.4.1 Organic Matter (OM) Decomposition; 2.4.2 Nutrient Transformation and Availability; 2.4.3 Plant Growth-Promoting (PGP) Activities; 2.4.4 Biocontrol Agents
  • 2.4.5 Soil Bioremediations2.4.6 Drought and Nutrient Stress/Deficiency; 2.5 Management of Rhizosphere System for Soil Sustainability and Productivity; 2.5.1 The Cultural Management/Practices; 2.5.2 Efficient Fertilization; 2.5.3 Use of Organic and Biofertilizers; 2.6 Concluding Remarks; References; 3: PGPR: Heart of Soil and Their Role in Soil Fertility; 3.1 Introduction; 3.2 Role of PGPR in Soil Fertility; 3.3 Plant Growth-Promoting Rhizobacteria (PGPR); 3.3.1 Classification of PGPRs; On the Basis of Location; Extracellular PGPRs (ePGPRs); Intracellular PGPRs (iPGPRs)
  • On the Basis of FunctionalityPlant Growth-Promoting Bacteria; Biocontrolling Bacteria; Stress Homeoregulating Bacteria; On the Basis of Activities; 3.4 PGPR Mechanism; 3.4.1 Direct Mechanism; 3.4.2 Indirect Mechanism; 3.5 Conclusions; References; 4: Strength of Microbes in Nutrient Cycling: A Key to Soil Health; 4.1 Introduction; 4.2 Soil Health; 4.3 Soil as a Microbial Habitat; 4.4 Microbial Decomposition of Organic Matter and Nutrient Availability; 4.5 Mineralization and Humification; 4.6 Role of Soil Enzymes in Organic Matter Decomposition; 4.7 Amylase
1 online resource
  • Front Cover; Atlas of Mycobacterium tuberculosis; Atlas of Mycobacterium tuberculosis; Copyright; Dedication; Contents; Preface; Acknowledgments; 1
  • Microscopic Anatomy of Mycobacterium tuberculosis; 3
  • Diversity in Cell Shape of Mycobacterium tuberculosis; 4
  • Cell Division in Mycobacterium tuberculosis; 5
  • Drug-Resistant Mycobacterium tuberculosis; 6
  • Latency in Mycobacterium tuberculosis.
vii, 469 pages : illustrations (some color) ; 26 cm
Science Library (Li and Ma)
1 online resource ( viii, 288 pages) : illustrations (some color).
  • ForewordLidia Mariana Fiuza, Ricardo Polanczyk and Neil Crickmore (Editors of the book)PrefaceLeon RabinovitchChapter 1. Bacillus thuringiensis characterization: morphology, physiology, biochemistry, pathotype, cellular and molecular aspectsLeon Rabinovitch, Vilmar Machado, Neiva Knaak, Diouneia Lisiane Berlitz, Ricardo Polanczyk and Lidia Mariana Fiuza Chapter 2. The biology, ecology and taxonomy of Bacillus thuringiensis and related bacteriaBen Raymond Chapter 3. Bacillus thuringiensis toxin classificationNeil Crickmore Chapter 4. Insecticidal proteins from Bacillus thuringiensis and their mechanism of action Alejandra Bravo, Sabino Pacheco, Isabel Gomez, Blanca Garcia-Gomez, Janette Onofre and Mario Soberon Chapter 5. Effect of Bacillus thuringiensis on parasitoids and predatorsSergio Antonio De Bortoli, Alessandra Marieli Vacari, Ricardo Antonio Polanczyk, Ana Carolina Pires Veiga and Roberto Marchi Goulart Chapter 6. Characterization of Bacillus thuringiensis using plasmid patterns, AFLP and rep-PCRFernando Hercos Valicente and Rosane Bezerra da Silva Chapter 7. New sequencing technologies and genomic analysis applied to Bacillus thuringiensisRoberto Franco Teixeira Correia, Anne Caroline Mascarenhas dos Santos, Raimundo Wagner de Souza Aguiar, Bergmann Morais Ribeiro and Fernando Lucas Melo Chapter 8. Expression of Bacillus thuringiensis in insect cellsBergmann Morais Ribeiro, Erica Soares Martins, Raimundo Wagner de Souza Aguiar and Roberto Franco Teixeira Correia Chapter 9. Bacillus thuringiensis: Different Targets and InteractionsLidia Mariana Fiuza, Diouneia Lisiane Berlitz, Jaime Vargas de Oliveira and Neiva Knaak Chapter 10. Specificity and cross-order activity of Bacillus thuringiensis pesticidal proteinsKees van Frankenhuyzen Chapter 11. The American Bacillus thuringiensis based biopesticides market Ricardo Antonio Polanczyk, Kees van Frankenhuyzen and Giuliano Pauli Chapter 12. Mass production, application, and market development of Bacillus thuringiensis Biopesticides in China Lin Li, Zhenmin Chen and Ziniu Yu Chapter 13. The role of Embrapa in the development of tools to control biological pests: a case of successRose Gomes Monnerat, Glaucia de Figueiredo Nachtigal, Ivan Cruz, Wagner Bettiol and Clara Beatriz Hoffman Campo Chapter 14. Bacillus entomopathogenic based biopesticides in vector control programs in BrazilClara Fatima Gomes Cavados, Wanderli Pedro Tadei, Rosemary Aparecida Roque, Leda Narcisa Regis, Claudia Maria Fontes de Oliveira, Helio Benites Gil and Carlos Jose Pereira da Cunha de Araujo-Coutinho Chapter 15. Resistance of mosquitoes to entomopathogenic bacterial based larvicides: current status and strategies for management Maria Helena Neves Lobo Silva-Filha Chapter 16. The importance of Bacillus thuringiensis in the context of genetically modified plants in Brazil Deise Maria Fontana Capalbo and Marise Tanaka Suzuki Chapter 17.Resistance of Spodoptera frugiperda to Bacillus thuringiensis proteins in in the Western Hemisphere Samuel Martinelli, Renato Assis de Carvalho, Patrick Marques Dourado and Graham Phillip Headâ .
  • (source: Nielsen Book Data)9783319566771 20170814
This volume presents a comprehensive perspective of the biopesticides Bacillus thuringiensis and Lysinibacillus sphaericus, from their basic biology to agriculture, forestry and public-health applications. It covers their ecology, virulence factors, and genetic characterization. The topics related to agriculture and forestry include mode of action, receptors of insect pests, and heterologous expression of toxins in insect cells and plants. Public-health researchers will find information on vector control programs with an emphasis on the Neotropical region. The book also discusses new products and the global market.
(source: Nielsen Book Data)9783319566771 20170814
EBSCOhost Access limited to 1 user
1 online resource (xv, 528 pages) : illustrations (some color). Digital: text file; PDF.
  • Identification of protein secretion systems in bacterial genomes using MacSyFinder / Sophie S. Abby and Eduardo P.C. Rocha
  • Protein sorting prediction / Henrik Nielsen
  • Cell fractionation / Melissa Petiti, Laetitia Houot, and Denis Duché
  • Defining lipoprotein localisation by fluorescence microscopy / Maria Guillermina Casabona, Mylène Robert-Genthon, Didier Grunwald, and Ina Attrée
  • Identification of lipoproteins using globomycin and radioactive palmitate / Nienke Buddelmeijer
  • Defining membrane protein localization by isopycnic density gradients / Rhys A. Dunstan, Iain D. Hay, and Trevor Lithgow
  • Cell surface exposure / Anna Konovalova
  • Probing inner membrane protein topology by proteolysis / Maxence S. Vincent and Eric Cascales
  • Mapping of membrane protein topology by substituted cysteine accessibility method (SCAM) / Mikhail Bogdanov
  • Defining membrane protein topology using pho-lac reporter fusions / Gouzel Karimova and Daniel Ladant
  • In vivo and in vitro protein-peptidoglycan interactions / Gang Li and S. Peter Howard
  • Measure of peptidoglycan hydrolase activity / Yoann G. Santin and Eric Cascales
  • Protein-protein interaction : Bacterial Two-Hybrid / Gouzel Karimova, Emilie Gauliard, Marilyne Davi, Scot P. Ouellette, and Daniel Ladant
  • Protein-protein interactions : yeast two-hybrid system / Jer-Sheng Lin and Erh-Min Lai
  • Protein-protein interactions : cytology two-hybrid / Krishnamohan Atmakuri
  • Fusion reporter approaches to monitoring transmembrane helix interactions in bacterial membranes / Laureen Logger, Abdelrahim Zoued, and Eric Cascales
  • Protein-protein interactions : co-immunoprecipitation / Jer-Sheng Lin and Erh-Min Lai
  • Protein-protein interaction : tandem affinity purification in bacteria / Julie P.M. Viala and Emmanuelle Bouveret
  • Site-directed and time-resolved photocrosslinking in cells metabolically labeled with radioisotopes / Raffaele Ieva
  • Protein-protein interactions : pull-down assays / Arthur Louche, Suzana P. Salcedo, and Sarah Bigot
  • Protein-protein interactions : surface plasmon resonance / Badreddine Douzi
  • Assessing energy-dependent protein conformational changes in the TonB system / Ray A. Larsen
  • Defining assembly pathways by fluorescence microscopy / Abdelrahim Zoued and Andreas Diepold
  • Large complexes : cloning strategy, production, and purification / Eric Durand and Roland Lloubes
  • Shearing and enrichment of extracellular type IV pili / Alba Katiria Gonzalez Rivera and Katrina T. Forest
  • Blue native PAGE analysis of bacterial secretion complexes / Susann Zilkenat, Tobias Dietsche, Julia V. Monjarás Feria, Claudia E. Torres-Vargas, Mehari Tesfazgi Mebrhatu, and Samuel Wagner
  • In situ imaging of bacterial secretion systems by electron cryotomography / Gregor L. Weiss, João M. Medeiros, and Martin Pilhofer
  • Structural analysis of protein complexes by cryo electron microscopy / Tiago R.D. Costa, Athanasios Ignatiou, and Elena V. Orlova
  • Bacterial filamentous appendages investigated by solid-state NMR spectroscopy / Birgit Habenstein and Antoine Loquet
  • Energy requirements for protein secretion via the flagellar type III secretion system / Marc Erhardt
  • Identification of effectors : precipitation of supernatant material / Nicolas Flaugnatti and Laure Journet
  • Screening for secretion of the type VI secretion system protein Hcp by enzyme-linked immunosorbent assay and colony blot / Brent S. Weber, Pek Man Ly, and Mario F. Feldman
  • Effector translocation : cya reporter assay / Suma Chakravarthy, Bethany Huot, and Brian H. Kvitko
  • Monitoring effector translocation using the TEM-1 beta-lactamase reporter system / Julie Allombert, Anne Vianney, and Xavier Charpentier
  • Effector translocation assay : differential solubilization / Irina S. Franco, Sara V. Pais, Nuno Charro, and Luís Jaime Mota
  • Quantitative determination of anti-bacterial activity during bacterial co-culture / Juliana Alcoforado Diniz, Birte Hollmann, and Sarah J. Coulthurst.
This volume details protocols that cover the broad arsenal of techniques used to study a secretion system from A to Z. Chapters focus on identifying and localizing the different subunits, defining interactions within subunits, monitoring conformational changes, purifying and imaging of large complexes, defining the assembly pathway by fluorescence microscopy and the role of energy during assembly and/or secretion, identifying secreted effectors as well as reporters to follow effector transport. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Bacterial Protein Secretion Systems: Methods and Protocol aims to provide techniques that are not restricted to the study of secretion systems but are also of specific interest for any researcher interested on multi-protein complexes of the bacterial cell envelope.
(source: Nielsen Book Data)9781493970315 20171009
1 online resource.
  • 1. The phylum Actinobacteria Paul A. Lawson2. Species in the Genus Bifidobacterium Paola Mattarelli, Bruno Biavati3. Related Genera Within the Family Bifidobacteriaceae Bruno Biavati, Paola Mattarelli4. Isolation, Cultivation and Storage of Bifidobacteria Monica Modesto5. Chemotaxonomic Features in the Bifidobacteriaceae Family Paola Mattarelli, Barbara Sgorbati6. Nutritional Requirements of Bifidobacteria Rachel Levantovsky, Cary R. Allen-Blevins, David A. Sela7. Stress Responses of Bifidobacteria: Oxygen and Bile Acid as the Stressors Shinji Kawasaki, Masamichi Watanabe, Satoru Fukiya, Atsushi Yokota8. Carbohydrate Metabolism in Bifidobacteria Muireann Egan, Douwe van Sinderen 9. Interactions Between Bifidobacteria, Milk Oligosaccharides and Neonate Hosts Guy I. Shani, Zachary T. Lewis, Ashanti M. Robinson, David A. Mills 10. Biological Activities and Applications of Bifidobacterial Exopolysaccharides: From the Bacteria and Host Perspective Nuria Castro-Bravo, Borja Sanchez, Abelardo Margolles, Patricia Ruas-Madiedo11. Folate and Bifidobacteria Thomas A. Andlid, Maria R. D'Aimmo, Jelena Jastrebova12. Bifidobacteria: Ecology and Coevolution with the Host Francesca Turroni, Christian Milani, Douwe van Sinderen, Marco Ventura13. Clinical Significance of Bifidobacteria Christian U. Riedel14. Honeybee-Specific Bifidobacteria and Lactobacilli Tobias Olofsson, Alejandra Vasquez15. Genetic Manipulation and Gene Modification Technologies in Bifidobacteria Satoru Fukiya, Mikiyasu Sakanaka, Atsushi Yokota16. Production of Probiotic Bifidobacteria Arthur C. Ouwehand, Sara Sherwin, Connie Sindelar, Amy B. Smith, Buffy Stahl17. Prebiotics, Probiotics and Synbiotics: A Bifidobacterial View Lorenzo Morelli, Maria L. Callegari, Vania Patrone 18. Evidence of the In Vitro and In Vivo Immunological Relevance of Bifidobacteria Susana Delgado, Lorena Ruiz, Arancha Hevia, Patricia Ruas-Madiedo, Abelardo Margolles, Borja Sanchez.
  • (source: Nielsen Book Data)9780128050606 20171017
The Bifidobacteria and Related Organisms: Biology, Taxonomy, Applications brings together authoritative reviews on all aspects of Bifidobacteria and related genera. Their place within the Phylum Actinobacteria is discussed first, and this is followed by descriptions of the genera Bifidobacterium, Alloscardovia, Aeriscardovia, Bombiscardovia, Gardnerella, Metascardovia, Parascardovia and Scardovia and the currently accredited species within those genera. The increased availability of genome sequences and molecular tools for studying bifidobacteria provides important information about their taxonomy, physiology and interactions with their host. Also considerations about common bifidobacterial core maintenance during the mutual coevolution of a host and its intestinal microbes could be relevant for health claims for the ability of symbiotic gut bacteria to provide health benefits to their host, and for evaluating such claims in scientifically valid experiments. Chemotaxonomy is important to our understanding of these genera and so is considered along with physiological and biochemical aspects before proceeding to examine clinical and other practical aspects. The ability to maintain pure cultures and to grow cells in industrial quantities when required for applications requires that the cells' environmental and nutritional needs are well understood. Some species are important clinically and as animal digestive tract synbionts-and even play a part in honey production-so these matters are considered along with milk oligosaccharides' roles in gut flora development in neonates.
(source: Nielsen Book Data)9780128050606 20171017
1 online resource.
  • Preface 1. Introduction: Keylevels of Biocommunication of Archaea 2. The Cooccurrence of Archaea and Bacteria among Diverse Globally Distributed Ecosystems 3. Direct Interspecies Electron Transfer Between Archaea and Bacteria 4. Why Archaea are Limited in their Exploitation of Other, Living Organisms 5. Archaeal Surface Structures and Their Role in Communication with the Extracellular Environment 6. Archaeal Biocommunication in Hot Springs Revealed by Metagenomics 7. Sexual Communication in Archaea, the Precursor to Eukaryotic Meiosis 8. Quorum Sensing in Archaea: Recent Advances and Emerging Directions 9. Biofilm Lifestyle of Thermophile and Acidophile Archaea 10. The Compressed Vocabulary of the Proteins of Archaea 11. KaiC-like ATPases as Signal Transduction Hubs in Archaea 12. Archaea were Trailblazers in Signaling Evolution: Protein Adaptation and Structural Fluidity as a Form of Intracellular Communication 13. Protein Phosphorylation-Dephosphorylation and Signal Processing in the Archaea 14. Secondary Metabolites in Archaea and Extreme Environments 15. Evolutionary Interaction Between Archaeal-Eukaryal Cell Lineages and Viruses 16. Inteins as Indicators of Bio-Communication 17. Riboswitches: Regulatory ncRNAs in Archaea 18. DNA Damage Repair in Archaea 19. Archaeal Lipids as an Adaptation to Higher Temperatures?
  • (source: Nielsen Book Data)9783319655352 20171211
Archaea represent a third domain of life with unique properties not found in the other domains. Archaea actively compete for environmental resources. They perceive themselves and can distinguish between `self' and `non-self'. They process and evaluate available information and then modify their behaviour accordingly. They assess their surroundings, estimate how much energy they need for particular goals, and then realize the optimum variant. These highly diverse competences show us that this is possible owing to sign(aling)- mediated communication processes within archaeal cells (intra-organismic), between the same, related and different archaeal species (interorganismic), and between archaea and nonarchaeal organisms (transorganismic). This is crucial in coordinating growth and development, shape and dynamics. Such communication must function both on the local level and between widely separated colony parts. This allows archaea to coordinate appropriate response behaviors in a differentiated manner to their current developmental status and physiological influences. This book will orientate further investigations on how archaeal ecosphere inhabitants communicate with each other to coordinate their behavioral patterns and whats the role of viruses in this highly dynamic interactional networks.
(source: Nielsen Book Data)9783319655352 20171211