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Book
xviii, 606 pages : illustrations (chiefly color) ; 29 cm
  • Introduction. 1. Nerve Cells and Nerve Impulses. 2. Synapses. 3. Anatomy and Research Methods. 4. Genetics, Evolution, Development, and Plasticity. 5. Vision. 6. Other Sensory Systems. 7. Movement. 8. Wakefulness and Sleep. 9. Internal Regulation. 10. Reproductive Behaviors. 11. Emotional Behaviors. 12. Learning, Memory, and Intelligence. 13. Cognitive Functions. 14. Psychological Disorders. Appendix A: Brief, Basic Chemistry. Appendix B: Society for Neuroscience Policies on the Use of Animals and Human Subjects in Research.
  • (source: Nielsen Book Data)9781337408202 20180319
The most widely used text in its course area, James W. Kalat's BIOLOGICAL PSYCHOLOGY has appealed to thousands of students before you. Why? Kalat's main goal is to make Biological Psychology understandable to Psychology students, not just to Biology majors and pre meds--and he delivers. Another goal is to convey the excitement of the search for biological explanations of behavior. Kalat believes that Biological Psychology is "the most interesting topic in the world, " and this text convinces many students--and maybe you, too--with clear writing, amusing anecdotes and intriguing examples. MindTap, an interactive online learning resource that integrates the text with videos, animations and a virtual bio-lab component, makes learning even easier and more enjoyable.
(source: Nielsen Book Data)9781337408202 20180319
Science Library (Li and Ma)
Book
1 volume (various pagings) ; 29 cm
  • 1. What Is Behavioral Neuroscience? 2. Functional Neuroanatomy and the Evolution of the Nervous System. 3. Neurophysiology: The Structure and Functions of the Cells of the Nervous System. 4. Psychopharmacology. 5. Genetics and the Development of the Human Brain. 6. Vision. 7. Nonvisual Sensation and Perception. 8. Movement. 9. Homeostasis, Motivation, and Reward. 10. Sexual Behavior. 11. Sleep and Waking. 12. Learning and Memory. 13. Cognition. 14. Emotion, Aggression, and Stress. 15. Neuropsychology. 16. Psychopathology.
  • (source: Nielsen Book Data)9781337570930 20180416
Do you have a strong science background? Or do you feel overwhelmed at the prospect of taking a behavioral neuroscience, biological psychology, or physiological psychology course? Either way, this text's clear writing, interesting examples, learning aids, and illustrations will keep you interested and on track. DISCOVERING BEHAVIORAL NEUROSCIENCE: AN INTRODUCTION TO BIOLOGICAL PSYCHOLOGY, 4th Edition includes classic concepts, current topics, and cutting-edge research to provide you with a foundational understanding of the structure and function of the nervous system and its relationship to both typical and disordered human behavior. You'll learn about the most current thinking in behavioral neuroscience while honing your critical thinking skills to prepare yourself for the future.
(source: Nielsen Book Data)9781337570930 20180416
Science Library (Li and Ma)
Book
xxviii, 506 pages ; 29 cm + 1 set of anaglyph glasses
Science Library (Li and Ma)
Book
1 online resource (xvii, 626 pages) : illustrations (some color).
  • Preface... Table of Contents... Contributing Authors... 1. Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (a1b1y1) Julia A. Hubbard, Bing Xiao, and Jon R. Wilson 2. Visualizing AMPK Drug Binding Sites through Crystallization of Full Length Phosphorylated a2b1y1 Heterotrimer Christopher G. Langendorf, Jonathan S. Oakhill, and Bruce E. Kemp 3. Biophysical Interactions of Direct AMPK Activators Ravi G. Kurumbail, Graham M. West, Venkatasubramanian Dharmarajan, Kris A. Borzilleri, Jane M. Withka, Jessica Ward, Allan R. Reyes, Francis Rajamohan, Patrick R. Griffin, and Matthew F. Calabrese 4. Biochemical Measurement of Glycogen: Method to Investigate the AMPK-Glycogen Relationship Elite Possik and Arnim Pause 5. Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK Fiona A. Fyffe, Simon A. Hawley, Alexander Gray, and D. Grahame Hardie 6. Applications of NMR and ITC for the Study of the Kinetics of Carbohydrate Binding by AMPK ss-Subunit Carbohydrate Binding Modules Paul R. Gooley, Ann Koay, and Jesse I. Mobbs 7. Bioinformatics Approach to Identify Novel AMPK Targets Brendan Gongol, Traci Marin, David A. Johnson, and John Y-J. Shyy 8. Studying AMPK in an Evolutionary Context Arpit Jain, Valentin Roustan, Wolfram Weckwerth, and Ingo Ebersberger 9. AMPK Protein Interaction Analyses by Yeast Two-Hybrid Pascual Sanz, Rosa Viana, and Maria Adelaida Garcia-Gimeno 10. Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells Jonathan S. Oakhill, John W. Scott, and Toby A. Dite 11. Knockdown of Human AMPK using the CRISPR-Cas9 Genome-Editing System Adrien Grenier, Pierre Sujibert, Severine Olivier, Helene Guermouche, Johanna Mondesir, Olivier Kosmider, Benoit Viollet, and Jerome Tamburini 12. Compound C/Dorsomorphin - Its Use and Misuse as an AMPK Inhibitor Biplab Dasgupta and William Seibel 13. Identifying the Heterotrimeric Complex Stoichiometry of AMPK in Skeletal Muscle by Immunoprecipitation Jesper B. Birk and Jorgen F. P. Wojtaszewski 14. Kinase Activity Determination of Specific AMPK Complexes/Heterotrimers in Skeletal Muscle Jesper B. Birk and Jorgen F. P. Wojtaszewski 15. Determination of Adenine Nucleotide Concentrations in Cells and Tissues by High Performance Liquid Chromatography Noemi Garcia-Tardon and Bruno Guigas 16. Intact Cell Assays to Monitor AMPK and Determine the Contribution of the AMP-Binding or ADaM Sites to Activation Simon A. Hawley, Fiona A. Fyffe, Fiona M. Russell, Graeme J. Gowans, and D. Grahame Hardie 17. Cellular Application of Genetically-Encoded Sensors and Impeders of AMPK Takafumi Miyamoto, Elmer Rho, Allen Kim, and Takanari Inoue 18. Assessing Mitochondrial Bioenergetics by Respirometry in Cells or Isolated Organelles Guillaume Vial and Bruno Guigas 19. Study of AMPK Regulated Metabolic Fluxes in Neurons using the Seahorse XFe Analyzer Claudia Marinangeli, Jerome Kluza, Philippe Marchetti, Luc Buee, and Valerie Vingtdeux 20. Investigating the Role of AMPK in Inflammation Sarah J. Mancini and Ian P. Salt 21. Studying the Role of AMPK in Cardiac Hypertrophy and Protein Synthesis Florence Mailleux, Christophe Beauloye, Jean-Luc Balligand, Sandrine Horman, and Luc Bertrand 22. Assessment of AMPK-Stimulated Cellular Long-Chain Fatty Acid and Glucose Uptake Joost J.F.P. Luiken, Dietbert Neumann, Jan F.C. Glatz, Will A. Coumans, Dipanjan Chanda, and Miranda Nabben 23. Measurement of AMPK-Induced Inhibition of Lipid Synthesis Flux in Cultured Cells Marc Foretz and Benoit Viollet 24. Studying the Role of AMPK in Autophagy Sarah Krieg, Bernhard Luscher, Joerg Vervoorts, and Marc Dohmen 25. Determining AMPK Activation via the Lysosomal v-ATPase-Ragulator-AXIN/LKB1 Axis Chen-Song Zhang, Mengqi Li, Yue Zong, and Sheng-Cai Lin 26. Manipulation and Measurement of AMPK Activity in Pancreatic Islets Aida Martinez-Sanchez, Marie-Sophie Nguyen-Tu, Isabelle Leclerc, and Guy A. Rutter 27. Analyzing AMPK Function in the Hypothalamus Patricia Seoane-Collazo and Miguel Lopez 28. Using Ex Vivo Kidney Slices to Study AMPK Effects on Kidney Proteins Renee Rao, Kazuhiro Omi, Roshan Rajani, Hui Li, and Nuria M. Pastor-Soler 29. A Flow Cytometry-Based Protocol to Measure Lymphocyte Viability upon Metabolic Stress Sebastien Denanglaire, Tiphene Pirnay, Oberdan Leo, and Fabienne Andris 30. Methods to Evaluate AMPK Regulation of Macrophage Cholesterol Homeostasis Nicholas D. LeBlond and Morgan D. Fullerton 31. Modulation of Vascular Function by AMPK: Assessment of NO Bioavailability and Surrogates of Oxidative Stress Swenja Kroeller-Schoen, Andreas Daiber, and Eberhard Schulz 32. Measurement of Reactive Oxygen Species (ROS) and Mitochondrial ROS in AMPK Knockout Mice Blood Vessels Qilong Wang and Ming-Hui Zou 33. Studying the Role of AMPK in Angiogenesis Katrin Spengler, Silke Lindenmuller, Nderim Kryeziu, Anne Knierim, and Regine Heller 34. Analysis of Muscle Stem Cell Fate through Modulation of AMPK Activity Marine Theret, Linda Gsaier, Sabrina Ben Larbi, Michele Weiss-Gayet, and Remi Mounier 35. Evaluating the Role of Host AMPK in Leishmania Burden Diana Moreira, Jerome Estaquier, Anabela Cordeiro-da-Silva, and Ricardo Silvestre 36. Analysis of Transgenerational Phenotypes Following Acute Atarvation in AMPK-Deficient C. elegans Emilie Demoinet and Richard Roy 37. Human γ2 AMPK Mutations Arash Yavari, Dhruv Sarma, and Eduardo B. Sternick.
  • (source: Nielsen Book Data)9781493975976 20180416
This volume explores the latest methods used to study AMPK by computational, biochemical, biophysical, cellular, and ex vivo and in vivo approaches. The chapters in this book cover specific topics, such as methods to measure change in cellular energy metabolism and analyze metabolic pathways regulated by AMPK; bioinformatics tools to identify AMPK targets; knockdown of AMPK by CRISPR-Cas9; production and crystallization of full-length human AMP-activated protein kinase; cell-free assays to measure the effects of regulatory ligands on AMPK; use of sensors of AMPK activity; AMPK protein interaction by yeast two-hybrid; the role of AMPK in inflammation and autophagy; analyzing the AMPK function in C. elegans and mammals (with special focus on skeletal muscle, blood vessels, kidneys, pancreatic islets and hypothalamus); and human γ2 AMPK mutations. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, AMPK: Methods and Protocols is a valuable resource for graduate students, postdoctoral researchers, and established investigators who are interested in the richly diverse AMPK field.
(source: Nielsen Book Data)9781493975976 20180416
Book
1 volume (various pagings) : color illustrations ; 29 cm
  • Part One Organization of the Body 1 Major Themes of Anatomy and PhysiologyATLAS A General Orientation to Human Anatomy 2 The Chemistry of Life 3 Cellular Form and Function 4 Genetics of Cellular Function 5 Histology Part Two Support and Movement 6 The Integumentary System 7 Bone Tissue 8 The Skeletal System 9 Joints 10 The Muscular SystemATLAS B Regional and Surface Anatomy 11 Muscular Tissue Part Three Internal Coordination and Control 12 Nervous Tissue 13 The Spinal Cord, Spinal Nerves, and Somatic Reflexes 14 The Brain and Cranial Nerves 15 The Autonomic Nervous System and Visceral Reflexes 16 Sense Organs 17 The Endocrine System Part Four Circulation and Defense 18 The Circulatory System: Blood 19 The Circulatory System: Heart 20 The Circulatory System: Blood Vessels and Circulation 21 The Lymphatic and Immune Systems Part Five Intake and Output 22 The Respiratory System 23 The Urinary System 24 Fluid, Electrolyte, and Acid - Base Balance 25 The Digestive System 26 Nutrition and Metabolism Part Six Reproduction and the Life Cycle 27 The Male Reproductive System 28 The Female Reproductive System 29 Human Development and Aging APPENDIX A: Periodic Table of the Elements APPENDIX B: Answer Keys APPENDIX C: Symbols, Weights, and Measures APPENDIX D: Biomedical Abbreviations APPENDIX E: The Genetic Code APPENDIX F: Lexicon of biomedical Word Elements APPENDIX G: Eighth Edition Changes in Terminology Glossary CreditsIndex.
  • (source: Nielsen Book Data)9781259277726 20170410
Master the story of Anatomy & Physiology with Saladin's Anatomy & Physiology: The Unity of Form and Function! Saladin's A&P helps students make connections by telling a story that will intrigue, engage, and inspire them. Saladin expertly weaves together science, clinical applications, history and evolution of the body with vibrant photos and art to convey the beauty and excitement of the subject. A consistent set of chapter learning tools helps students identify and retain key concepts while the stunning visual program provides a realistic view of body structures and processes. Saladin's text requires no prior knowledge of college chemistry or cell biology, and is designed for a two-semester A&P course.
(source: Nielsen Book Data)9781259277726 20170410
Science Library (Li and Ma)
Book
1 online resource : illustrations
  • 1. Brief analysis of the auditory system organization and its physiologic basis 2. The Physiologic Basis of Sleep 3. Notes on Information Processing 4. Auditory Information Processing during Sleep 5. Auditory Unit Activity in Sleep 6. Auditory Influences on Sleep 7. Tinnitus treatment during sleep 8. Other sensory modalities in sleep 9. Final Conclusions.
  • (source: Nielsen Book Data)9780128104767 20180611
The Auditory System in Sleep, Second Edition presents a view of a sensory system working in a different state, that of the sleeping brain. This updated edition contains new chapters on topics such as implanted deaf patients and sleep and tinnitus treatments. It is written for basic auditory system and sleep researchers, as well as practitioners and clinicians in the Auditory/Sensory Neurosciences and Sleep Medicine. As the auditory system is always "open", thus receiving information from the environment and the body itself (conscious and unconscious data), the incoming sensory information may alter sleep and waking physiology, and conversely, the sleeping brain. This book draws information from evoked potentials, fMRI, PET, SPECT, lesions, and more.
(source: Nielsen Book Data)9780128104767 20180611
Book
1 online resource (xii, 355 pages) : illustrations (some color).
Book
1 online resource. Digital: text file; PDF.
  • 1. Strontium in ecosystem: Transfer in plants via root system. S.Chatterjee, C. Walther, D.K.Gupta, Gottfried Wilhelm Leibniz Universitat Hannover Institut fur Radiookologie und Strahlenschutz (IRS)Herrenhauser Strasse 2,30419 Hannover, Germany2. Bioavailability of strontium in soils: Influence of radionuclide speciation on the soil-plant transfer. J. Guillen, A. Salas, J.A. Corbacho, A. Baeza LARUEX (Environmental Radioactivity Laboratory)Dpt. Applied Physics, Faculty of Veterinary Sciences, University of Extremadura, Avda. Universidad, s/n, 10003, Caceres, Spain3. Distribution of strontium in soil: Interception, weathering, speciation and translocation to plants.S. Dubchak, State Ecological Academy of Postgraduate Education and Management 03035, V. Lypkivsky str. 35, building 2, Kiev, Ukraine 4. Accumulation of the 90Sr by plants of different taxonomic groups from the soils at the Eastern Ural Radioactive Trace.L.N. Mikhailovskaya, V.N. Pozolotina, E.V. Antonova, Laboratory of Population Radiobiology, Institute of Plant & Animal Ecology, Ural Branch of the Russian Academy of Sciences, 202 8 Marta St., 620144 Ekaterinburg, Russia5. Exposure of plants due to 90Sr contamination in the area of Eastern Ural Radioactive Trace.L.N. Mikhailovskaya, I.V. Yarmoshenko, G.P. Malinovsky, V.N. Pozolotina, E.V. Antonova, Ecology, Ural Branch, Russian Academy of Sciences, Sophy Kovalevskoy 20, 620219 Ekaterinburg, Russia6. Laws of behaviour of strontium-90 in the terrestrial and aquatic ecosystems of the Southern Urals.N.N. Kazachonok, I.Y. Popova, Belarus-Russian University, st. Mira, 43, Mogilev-212030, Belarus 7. Migration of the 90Sr in the ecosystems of the Chernobyl Exclusive Zone (Belarussian Part).S. Kalinichenko, A. Nikitin, O. Shurankova, I. Cheshyk Institute of the Radiobiology of the National Academy of Sciences of Belarus, Gomel, Belarus, 8. Contamination of the forest wood of exclusion zone of Chernobyl NPP by 90Sr according to data of 2005-2015.V. Zabrotski, Polessje State Radiation-Ecological Reservation, Tereshkova str. 7, Khoiniki, Gomel region, 247618, Belarus9. Peculiarities of 90Sr distribution in soil system - Scots pine (Pinus sylvestris L.).Dr. I.P. Bataitiene, Utena University of Applied Sciences, Faculty of Business and Technologies, Department of Environment Protection Engineering, Maironio 17 str., LT-28142, Utena, Lithuania10. 87Sr/86Sr in Vitis vinifera and its relationships with the geological substratum of the vineyard.Dr. S. Conticelli, Dipartimento di Scienze della Terra, Universita degli Studi di Firenze, Via Giorgio La Pira, 4, I-50121, Firenze, Italy11. Hereditary component of variation in 90Sr kinetics.Dr. V.I. Starichenko, Institute of Plants and Animal Ecology, Ural Branch, Russian Academy of Sciences, Vos'mogo Marta St. 202, 620144, Ekaterinburg, Russia12. Soil-to-crop transfer factors of alkaline earth elements and comparison with global fallout 90Sr.Dr. K. Tagami, Biospheric Assessment for Waste Disposal Team, National Institute of Radiological Sciences, Anagawa 4-9-1, Inage-ku, Chiba 263-8555, Japan Appendice.
  • (source: Nielsen Book Data)9783319665733 20180115
This book provides extensive and comprehensive knowledge to researchers and academics who work on strontium contaminated areas. Topics covered include impact on plants and environment, as well as remediation strategies. This book will inform graduate and undergraduate students who are specializing in radioecology, especially strontium uptake via soil to plants, safe disposal of strontium waste, remediation legacies and impact of strontium waste material on the natural and manmade environment. A broad overview of reviews is provided covering a number of original publications on strontium plant uptake, including case studies that present the latest technological developments and future trends for investigating strontium mobility in soil and treatment of strontium contaminated areas.
(source: Nielsen Book Data)9783319665733 20180115
Book
1 online resource : illustrations.
  • 1. Introduction 2. Methodologies for studying bioactive polysaccharides 3. Beta-Glucans from Fungi 4. Curdlan and derivatives 5. Dendronan from Dendrobium officinale and Aloe 6. Complex Glucomannan from Ganoderma atrum 7. Cordyceps Polysaccharides 8. Tea Polysaccharides 9. Psyllium Polysaccharides 10. Other Herbal Polysaccharides.
  • (source: Nielsen Book Data)9780128094181 20171204
Bioactive Polysaccharides offers a comprehensive review of the structures and bioactivities of bioactive polysaccharides isolated from traditional herbs, fungi, and seaweeds. It describes and discusses specific topics based on the authors' rich experience, including extraction technologies, practical techniques required for purification and fractionation, strategies and skills for elucidating the fine structures, in-vitro and in-vivo protocols, and methodologies for evaluating the specific bioactivities, including immune-modulating activities, anti-cancer activities, anti-oxidant activities, and others. This unique book also discusses partial structure-functionality (bioactivities) relationships based on conformational studies. This comprehensive work can be used as a handbook to explore potential applications in foods, pharmaceuticals, and nutraceutical areas for commercial interests.
(source: Nielsen Book Data)9780128094181 20171204
Book
1 online resource. Digital: text file; PDF.
  • Basic elements of viscoelasticity.- Reaction processes (chemical kinetics) and their application to muscle biology.- How to characterize chemical reactions occurring in muscle fibers?.- Structure and function of muscle cells.- Mathematics needed to solve problems of contraction.- Computer interfacing of experimental apparatus.- Appendices.
  • (source: Nielsen Book Data)9783319720340 20180409
This book is written to help and enable students in how to observe biological specimens in terms of viscosity, mass, elasticity and work producing elements. The observations are related to underlying chemical reactions by means of strain (fractional length change) sensitivity of the reactions, and a theory is developed how to connect these. Their mathematical derivation is complex when three or more states are involved, but a method is presented here to demonstrate how to simplify this complex problem. Basic mathematical solutions that are useful for this book, are presented (Fourier and Laplace transforms, differential equations, matrix operations) together with Fortran programs in the Appendix.
(source: Nielsen Book Data)9783319720340 20180409
Book
1 online resource. Digital: text file; PDF.
  • Introduction.- Cycling.- Force, Velocity and Power in Cycling.- Pedalling Technique, Effectiveness and Coordination.- Influence of Gear Ratios.- Measurements on Cycle Ergometers.- Ballistic Movements of Lower and Upper Limbs: Jumping and Pushing.-Simple Method for Measuring Jump Height and Power during Rebound and Drop Jump.- Simple Method for Measuring Force, Velocity and Power during Jumping.- Optimal Force-Velocity Profile in Jumping: Measurement and Relationship with Performance.- Simple Method for Measuring Stiffness during Hopping.- Simple Method for Measuring Force, Velocity, Power and Force-Velocity profile of Upper Limbs.- Running.- Simple Method for Measuring Lower Limb Stiffness during Running.- Measuring the Energetic Cost of Sprint Running.- Simple Method for Measuring Force, Velocity, Power and Force-Velocity profile and Optimal Force-Velocity profile during Sprint Running.- Measurements on Sprint Instrumented Treadmills.- Effectiveness of Force Production during Sprint Running.
  • (source: Nielsen Book Data)9783319056326 20180416
This book presents an account of innovative methods and, for most of them, gives direct and practical insights into how practitioners can benefit from their use in their everyday practice. It also explains how to interpret the data measured, and the underlying neuromechanical and biomechanical factors related to sports performance. Written and edited by the same researchers who proposed and validated these methods, this book not only presents innovative methods for an efficient training and testing process (most of which are based on very simple technology and data processing methods), but also discusses the associated background information. Although it is a young scientific discipline, sport biomechanics has taken on an important role in routine sports training, medicine and rehabilitation. It allows both a better understanding of human locomotion and performance and better design of training and injury prevention. In those processes, the testing of athletes is crucial, and the quality and quantity of the variables analysed directly influences the efficiency of physicians', coaches', physiotherapists' and other practitioners' interventions.
(source: Nielsen Book Data)9783319056326 20180416
Book
1 online resource.
  • Frontmatter
  • Preface
  • Contents
  • List of abbreviations
  • 1. Introduction
  • 2. Movement
  • 3. Vision
  • 4. Smell and Taste
  • 5. Hearing
  • 6. Skin, The Body's Largest Organ
  • 7. Future Developments
  • Index
Book
1 online resource.
  • Probabilities and Statistics in Chemical and Biothermodynamics Elementary Events. How Probabilities Combine. Permutation versus composition. Discrete Probability Distributions Continuous Distributions Mathematical Tools in Thermodynamics Calculus in Thermodynamics. Fitting continuous curves to discrete data. Determining the covariance matrix in least-squares fitting. Model testing with the 2 and f-ratio probability distributions. The Framework of Thermodynamics and the First Law What is Thermodynamics and What Does it Treat? Dividing up the Universe: System and Surroundings Equilibrium, Changes of State, and Reversibility Thermodynamic Variables and Equations of State The First law of Thermodynamics Work The reversible work associated with four fundamental changes of state. The heat flow associated with the four fundamental changes in an ideal gas. The work associated with the irreversible expansion of an ideal gas. The connection between heat capacities and state functions. A non-ideal model: the van der Walls equation of state The Second Law and Entropy Some familiar examples of spontaneous change. Spontaneous change and statistics The directionality of heat flow at the macroscopic (classical) level Free Energy as a Potential for the Laboratory and Biology Internal energy as a potential--combining the first and second laws. Contributions of different chemical species to thermodynamic state functions-molar quantities. Partial pressures of mixtures of gases. Legendre transforms of a single variable. Using Chemical Potentials to Describe Phase Transitions Phases and their transformations. The condition for equilibrium between two phases. How chemical potentials of different phases depend on temperature and pressure: deriving a T-p phase diagram for water. Additional restrictions from the phase diagram: the Clausius-Clapeyron equation and Gibbs' phase rule. The Concentration Dependence of Chemical Potential, Mixing, and Reactions The dependence of chemical potential on concentration. A simple lattice model for nonideal solution behavior. Chemical reactions Similarities (and differences) between free energies of reaction and mixing. How chemical equilibrium depends on temperature How chemical equilibrium depends on pressure Conformational Equilibrium Macromolecular structure. A simple two-state model for conformational transitions. Simultaneous visualization of N and D. The thermal unfolding transition as a way to determine Kfold and G . A simple geometric way to connect Yobs to Kfold. Fitting conformational transitions to analyze the thermodynamics of unfolding. A more realistic model thermal unfolding of proteins: the constant heat capacity model. Measurement of thermal denaturation by differential scanning calorimetry. Chemical denaturation of proteins. APPENDIX 1: Differential Scanning Calorimetry Ensembles that Interact with their Surroundings Heat exchange and the canonical ensemble. The canonical partition function. A canonical ensemble representing a three particle isothermal system. The isothermal isobaric ensemble and Gibbs free energy. Partition Functions for Single Molecules and Chemical Reactions A canonical partition function for a system with one molecule. The relationship between the molecular and canonical partition functions. An isothermal-isobaric molecular partition function. A statistical thermodynamic approach to chemical reaction. The Helix-Coil Transition The noncooperative homopolymer model. The noncooperative heteropolymer model. Coupling between the sites and the basis for cooperativity Coupling between residues through "nearest-neighbor" models Ligand Binding Equilibria from a Macroscopic Perspective Ligand Binding to a single site Practical issues in measuring and analyzing binding curves Binding of multiple ligands A macroscopic representation of multiple ligand binding. The binding polynomial P: a partition function for ligand binding. An example-the macroscopic binding of two ligands. Binding to multiple different ligands: "heterotropic" binding A general framework to represent thermodynamic linkage between multiple independent ligands. Ligand Binding Equilibria from a Microscopic Perspective. An example of general microscopic binding: three ligand binding sites. Simplifications to microscopic binding models. Binding to s identical, independent sites. Binding to two classes of independent sites. Binding to identical coupled sites Explicit structural models for coupling among between binding sites Allostery in ligand binding.
  • (source: Nielsen Book Data)9781439800195 20171023
This book introduces the concepts and practical tools necessary to understand the behavior of biological macromolecules at a quantitative level. It begins by describing biochemical phenomena using principles of classical and statistical thermodynamics. Unlike other books, this text goes beyond theory to explain in detail how the equations are applied to the analysis of experimental measurements. This emphasis on real-world applications is continued throughout and is a major feature of the book.
(source: Nielsen Book Data)9781439800195 20171023
EBSCOhost Access limited to 1 user
Book
1 online resource (542 pages).
  • Bio-Based Graft Copolymers For Toxic Ion Removal Chemically Modified Biopoplymers For Antimicrobial Applications Starch Based Graft Copolymer For Toxic Ion Bio-Based Graft Copolymers For Controlling Bleeding During Neurosurgical Procedures Bio-Based Polymers For Application As Novel Polymeric Material As Flocculant Chitosan Based Graft Copolymer For Organic Persistent Pollutants Removal Use Of Bio-Polymers Derivatives In Recovery Processes Biopolymers For Biomedical Applications Graft Co-Cpolymers In Antimicrobial Applications Biopolymers For Application As Adsorbent Recent Application Of Amphiphilic Starch-Based Graft Copolymers Cellulose-Based Graft Copolymers: Structure, And Application Intelligent Responsive Copolymers Based On Renewable Materials: Structure And Applications Surface Grafting Of Bio-Based Nanowhiskers Bio-Based Nanograft Copolymers: Applications Sulfonyl-Terminated Bio-Polymer-Grafted- Magnetic Nanoparticles For The Controlled Delivery Of Medicines Grafting Of Biopolymer Derivatives By Cuaac Click Chemistry Bipyridine End-Functionalized Biopolymer: Advances And Applications.
  • (source: Nielsen Book Data)9780128104620 20180306
Biopolymer Grafting: Applicationsã presents the latest research and developments in the practical application of these methods in industry, both to enable polymer scientists and engineers to keep up with the latest research trends, as well as to propose ideas for further research and application. Research into bio-based polymers has become increasingly prevalent. However, due to challenges related to the properties of these materials compared to synthetic polymers-such as their resistance to chemicals or weather-uptake has not dramatically increased yet. As a result, improvements in surface modification of bio-polymers through graft copolymerization are enormously important, because they will widen the scope of their applications. Relevant industries for application of these methods include automotive, construction, food, packaging, agriculture, textiles and paper. This book provides an overview of the developments made in the area of biopolymer-based graft polymers. Advantages, disadvantages and suggestions for future works are discussed, assisting materials scientists and researchers in mapping out the future of these new "green" materials through value addition to enhance their use.
(source: Nielsen Book Data)9780128104620 20180306
Book
1 online resource (596 pages) : illustrations (some color), tables.
  • 1. Synthesis and Characterization of Graft-Copolymers of Plant Polysaccharideses 2. Functional Separation Membranes from Grafted Biopolymers: Synthesis and Properties 3. Alginate Based Graft Copolymers: Structure and Synthesis 4. Polysaccharides in Alternative Methods for Insulin Delivery 5. Development of Bioactive Paper by Capsaicin Grafting onto Cellulose 6. Peptide-Based Derivative-Grafted Silica for Molecular Recognition System: Synthesis and Characterization 7. Graft Copolymer of Chitosan: Structure and Chemistry 8. Nano Polymers: Graphene and Functionalization 9. Cellulose Nanocrystals Functionalization by Grafting 10. Bioactive Materials Based on Biopolymers Grafted on Conducting Polymers: Recent Trends in Biomedical Field and Sensing 11. Grafting of Polysaccharides: Recent Advances 12. Grafted Nanocellulose as an Advanced Smart Biopolymer.
  • (source: Nielsen Book Data)9780323481045 20180306
Biopolymer Grafting: Synthesis and Properties presents the latest research and developments in fundamental of synthesis and properties of biopolymer-based graft copolymers. The book presents a broad overview of the biopolymer grafting process, along with trends in the field. It also introduces a range of grafting methods which lead to materials with enhanced properties for a range of practical applications, along with the positives and limitations of these techniques. The book bridges the knowledge gap between the scientific principles and industrial applications of polymer grafting. This book covers synthesis and characterization of graft-copolymers of plant polysaccharides, functional separation membranes from grafted biopolymers, and polysaccharides in alternative methods for insulin delivery. Recent trends and advances in this area are discussed, assisting materials scientists and researchers in mapping out the future of these new "green" materials through value addition to enhance their use.
(source: Nielsen Book Data)9780323481045 20180306
Book
1 online resource (596 pages) : illustrations (some color), tables.
  • 1. Synthesis and Characterization of Graft-Copolymers of Plant Polysaccharideses 2. Functional Separation Membranes from Grafted Biopolymers: Synthesis and Properties 3. Alginate Based Graft Copolymers: Structure and Synthesis 4. Polysaccharides in Alternative Methods for Insulin Delivery 5. Development of Bioactive Paper by Capsaicin Grafting onto Cellulose 6. Peptide-Based Derivative-Grafted Silica for Molecular Recognition System: Synthesis and Characterization 7. Graft Copolymer of Chitosan: Structure and Chemistry 8. Nano Polymers: Graphene and Functionalization 9. Cellulose Nanocrystals Functionalization by Grafting 10. Bioactive Materials Based on Biopolymers Grafted on Conducting Polymers: Recent Trends in Biomedical Field and Sensing 11. Grafting of Polysaccharides: Recent Advances 12. Grafted Nanocellulose as an Advanced Smart Biopolymer.
  • (source: Nielsen Book Data)9780323481045 20180306
Biopolymer Grafting: Synthesis and Properties presents the latest research and developments in fundamental of synthesis and properties of biopolymer-based graft copolymers. The book presents a broad overview of the biopolymer grafting process, along with trends in the field. It also introduces a range of grafting methods which lead to materials with enhanced properties for a range of practical applications, along with the positives and limitations of these techniques. The book bridges the knowledge gap between the scientific principles and industrial applications of polymer grafting. This book covers synthesis and characterization of graft-copolymers of plant polysaccharides, functional separation membranes from grafted biopolymers, and polysaccharides in alternative methods for insulin delivery. Recent trends and advances in this area are discussed, assisting materials scientists and researchers in mapping out the future of these new "green" materials through value addition to enhance their use.
(source: Nielsen Book Data)9780323481045 20180306

17. Biopsychology [2018]

Book
xxiii, 595 pages : color illustrations ; 29 cm
  • What is biopsychology?
  • Foundations of biopsychology
  • Sensory and motor systems
  • Brain plasticity
  • Biopsychology of motivation
  • Disorders of cognition and emotion.
For courses in Physiological Psychology and Biopsychology Explore how the central nervous system governs behavior Biopsychology presents a clear, engaging introduction to biopsychological theory and research through a unique combination of biopsychological science and personal, reader-oriented discourse. Original author John Pinel and new co-author Steven Barnes address students directly and interweave the fundamentals of the field with clinical case studies, useful metaphors, and memorable anecdotes that make course material personally and socially relevant to readers. In addition to expanded learning objectives that guide students through the course, the Tenth Edition has been thoroughly updated to reflect this rapidly progressing scientific field. Available to package with Biosychology, Tenth Edition, MyLab(TM) Psychology is an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. MyLab Psychology is ideal for courses requiring robust assessments. Biosychology, Tenth Edition is also available via Revel(TM), an interactive digital learning environment that replaces the print textbook, enabling students to read, practice, and study in one continuous experience. Revel is ideal for courses where student engagement and mobile access are important. Note: You are purchasing a standalone product; Pearson MyLab does not come packaged with this content. Students, if interested in purchasing this title with MyLab, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. 0134743369 / 9780134743363 Biopsychology plus MyLab Psychology with eText - Access Card Package, 10/e Package consists of: 0134203690 / 9780134203690 Biopsychology, 10/e 0134727746 / 9780134727745 MyLab Psychology with eText Access Card .
(source: Nielsen Book Data)9780134203690 20170306
Science Library (Li and Ma)
Book
xxi, 587 pages ; 28 cm
Science Library (Li and Ma)
Book
1 online resource.
  • Front Cover; Cell Surface GRP78, a New Paradigm in Signal Transduction Biology; Copyright Page; Contents; List of Contributors; Preface; 1 An Historical Perspective: Cell Surface GRP78, a New Paradigm in Signal Transduction Biology; Discovery of Cell Surface GRP78; GRP78 and Cancer Cell Biology; A Most Complex Signaling Mechanism; References; 2 The Endoplasmic Reticulum Chaperone GRP78 Also Functions as a Cell Surface Signaling Receptor; Introduction; Release of CS-GRP78 Into the Extracellular Environment; Secreted GRP78; GRP78 in Exosomes; Induction of GRP78 to the Cell Surface
  • CS-GRP78 Ligands and Their Cellular EffectsCS-GRP78 Forms Complexes With a Variety of Cell-Surface Anchored Proteins; CS-GRP78 Controls Key Oncogenic Signaling Pathways; Biological Functions of CS-GRP78 in Cancer; Cell Survival and Proliferation; Apoptosis; Invasion and Migration; Transcriptional Activation; Metabolism; The Role of CS-GRP78 in Other Physiological Diseases; Angiogenesis; Virus Internalization; Inflammation and Immunity; Arthritis; Therapeutic Targeting of CS-GRP78; GRP78 Autoantibodies and Their Physiological Roles; Concluding Remarks; References
  • 3 Cell Surface GRP78: Anchoring and Translocation Mechanisms and Therapeutic Potential in CancerIntroduction; Anchoring on the Cell Surface; Cell Surface Anchoring of ER-Transmembrane Chaperones; Cell Surface Anchoring of Peripheral Proteins; CS-GRP78 Binding Ligands, Membrane Proteins and Functions; Translocation Mechanisms; Intrinsic Factors; Protein-Protein Interaction in GRP78 Translocation; Trafficking Routes; Therapeutic Potential in Cancer; Antibodies; Peptide Conjugates; Proapoptotic Ligands; Conclusions and Perspectives; References
  • 4 Cell Surface GRP78: A Novel Regulator of Tissue Factor Procoagulant ActivityThe 78 kDa Glucose-Regulated Protein (GRP78); GRP78 Protein Structure; Translocation of GRP78 to the Cell Surface; Regulating the Levels of Cell Surface GRP78; Nonchaperone Functions of GRP78; Ca2+ Binding Protein; GRP78 and Pathology; Anti-GRP78 Autoantibodies and Cancer; GRP78 and the Coagulation System; Tissue Factor; The Role of Tissue Factor in Hemostasis; Tissue Factor Structure; Tissue Factor and Disease; Regulation of Tissue Factor Activity; Tissue Factor Dimerization; Altered Phospholipid Asymmetry
  • Tissue Factor Compartmentalization in CaveolaeTissue Factor Disulfide Bond Isomerization; Regulation of Tissue Factor by Cell Surface GRP78; Implication of TF Activation via Cell Surface GRP78 in Cancer; Conclusion; References; 5 Novel Cell Surface Targets for the Plasminogen Activating System in the Brain: Implications for Human Disease; Introduction; The Voltage-Dependent Anion Channel 1; Functions of Voltage-Dependent Anion Channel; The Plasminogen Activator System in the Brain; GRP78 and VDAC in the Brain; The Voltage-Dependent Anion Channel and Beta-Amyloid Peptides
Software/Multimedia
1 online resource (467 p.) : ill. (some col.)
  • Physiology of blood flow and metabolism
  • Models of blood flow and metabolism
  • Global control of blood flow
  • Local control of perfusion
  • Externally-based measurements
  • Internally-based measurements
  • Global changes in cerebral blood flow and metabolism
  • Local changes in cerebral blood flow and metabolism
  • Conclusions.
"This book describes the way in which the human brain is supplied with blood and how the brain uses this to provide nutrients, primarily oxygen and glucose, to brain cells in order to maintain healthy brain function. In particular, it focuses on the quantitative nature of blood flow and metabolism. The book covers models of blood flow and metabolism and how these can be measured using a variety of imaging and non-imaging techniques. It also examines how cerebral blood flow is controlled in response to a wide variety of challenges and how it changes with normal physiological variation and in response to a large number of pathological conditions, including stroke and dementia. As the first substantial book for over ten years in a fast-changing field, it highlights how the subject has progressed in the last couple of decades. It tackles the subject in a quantitative way, underlining its importance in both technical and clinical fields. Audiences with a technical or clinical background, especially researchers and postgraduate students in biomedical engineering or medicine, will find this a valuable read."--Publisher's website.