xv, 363 p. : ill. (some col.) ; 24 cm.
Surface modification of magnesium and its alloys for biomedical applications: Biological interactions, mechanical properties and testing, the first of two volumes, is an essential guide on the use of magnesium as a degradable implant material. Due to their excellent biocompatibility and biodegradability, magnesium based degradable implants provide a viable option for the permanent metallic implants. This volume focuses on the fundamental concepts of surface modification of magnesium, its biological interactions, mechanical properties and, in vitro and in vivo testing. The contents of volume 1 is organized and presented in three parts. Part 1 reviews the fundamental aspects of surface modification of magnesium, including surface design, opportunities, challenges and its role in revolutionizing biodegradable biomaterials. Part 2 addresses the biological and mechanical properties covering an in vivo approach to the bioabsorbable behavior of magnesium alloys, mechanical integrity and, the effects of amino acids and proteins on the performance of surface modified magnesium. Part 3 delves in to testing and characterization, exploring the biocompatibility and effects on fatigue life alongside the primary characteristics of surface modified magnesium. All chapters are written by experts, this two volume series provides systematic and thorough coverage of all major modification technologies and coating types of magnesium and its alloys for biomedical applications. * Expert analysis of the fundamentals in surface modification of magnesium and its alloys for biomedical applications * Includes biological interactions and mechanical properties * Focuses on testing and characterisation, as well as biocompatibility.
(source: Nielsen Book Data)9781782420774 20160618
Engineering Library (Terman)
xiv, 454 p. : ill. ; 28 cm.
Now in its fourth edition, "Basic Biomechanics of the Musculoskeletal System" uses a direct and comprehensive approach to present students with a working knowledge of biomechanical principles of use in the evaluation and treatment of musculoskeletal dysfunction.
(source: Nielsen Book Data)9781609133351 20160609
Engineering Library (Terman)
xiii, 672 p. : ill. ; 26 cm.
  • Contributors. Preface. 1. Introduction. 1.1 Definition of Biomechanics (B. M. Nigg). 1.2 Selected Historical Highlights (B. M. Nigg). 1.3 Mechanics (B. M. Nigg). 1.4 references. 2. Biological Materials. 2.1 Definitions and Comments. 2.2 Selected Historical Highlights. 2.3 Bone (S. K. Boyd and B. M. Nigg). 2.4 Articular cartilage (W. Herzog and S. Federico). 2.5 Ligament (G. M. Thornton, C. B. Frank and N. G. Shrive). 2.6 Tendon/Aponeurosis (W. Herzog). 2.7 Muscle (W. Herzog). 2.8 Adaptation of Biological materials to Exercise, Disuse and Aging (R. F. Zernicke, S. Judex and C. Lorincz). 2.9 Joints (B. M. Nigg and W. Herzog). 2.10 Additional Examples. 2.11 References. 3. Measuring Techniques. 3.1 Definitions and Comments. 3.2 Selected Historical Highlights. 3.3 Force (B. M. Nigg). 3.4 Pressure Distribution (B. M. Nigg). 3.5 Acceleration (B. M. Nigg and K. A. Boyer). 3.6 Optical Methods (B. M. Nigg, G. K. Cole and I.C. Wright). 3.7 Strain Measurement (N. Shrive). 3.8 EMG (V. von Tscharner and W. Herzog). 3.9 Inertial Porperties of the Human or animal Body (B. M. Nigg). 3.10 Additional Examples. 3.11 References. 4. Modelling. 4.1 Definitions and Comments. 4.2 Selected Historical Highlights. 4.3 A Nearly Possible Story (B. M. Nigg). 4.4 general Comments About Modelling (B. M. Nigg). 4.5 Force System Analysis (B. M. Nigg). 4.6 Mathematical Determinate Systems (B. M. Nigg). 4.7 Mathematically Indeterminate Systems (W. Herzog). 4.8 Simulation (A. J. van den Bogert and B. M. Nigg). 4.9 Additional Examples. 4.10 References. Index.
  • (source: Nielsen Book Data)9780470017678 20160528
The latest edition of this well organised and authoritative book provides a comprehensive account of the mechanics of the neuro-musculo-skeletal system. Covering the key areas including the properties of biomaterials, common measuring techniques and modelling, "Biomechanics of the Musculo-Skeletal System, Third Edition" also integrates historical aspects thus building a bridge between old and familiar knowledge and the latest developments in biomechanics. As with the previous edition there are numerous applications and extensive questions and answers at the end of sections. Specific changes for this edition include: major revision of the section on biological materials including bone, cartilage, ligament, tendon, muscle and joints and new discussion of failure and healing; extensive updating of material covering force, pressure distribution, optical methods and simulation; and, increase in the number and type of applications across a broad range of disciplines. "Biomechanics of the Musculo-Skeletal System, Third Edition" is an invaluable resource for all students, professionals and researchers concerned with biomechanical aspects of the human or animal body.
(source: Nielsen Book Data)9780470017678 20160528
Engineering Library (Terman)
xvi, 784 p. : ill. ; 24 cm.
  • Foreword.Preface.Contributors.Chapter 1: Physical characteristics of sound (RD Knight and DM Baguley).Chapter 2: Measurement of noise (Paul Radomskij).Chapter 3: Interactions between noise exposure and ageing: peripheral and central auditory systems (Sandra L McFadden and James F Willott).Chapter 4: Interaction of noise-induced hearing loss and ageing: epidemiological aspects (Doris-Eva Bamiou and Mark E Lutman).Chapter 5: Cochlear pathophysiology in response to hazardous noise (Carole M Hackney and David N Furness).Chapter 6: Functional changes in the central auditory system after noise-induced cochlear damage (RJ Salvi, J Wang and DM Caspary).Chapter 7: Factors determining an individual's susceptibility to noise damage (Deepak Prasher).Chapter 8: Measurement of hearing thresholds (Stig Arlinger).Chapter 9: Noise-induced hearing loss and tinnitus in children - a matter of diagnostic criteria (KM Holgers, A Bratthall and ML Barrenas)?Chapter 10: Clinical diagnosis of noise-induced hearing loss (Ian Colvin and Linda Luxon).Chapter 11: Disability assessment in noise-induced hearing loss (Philip H Jones).Chapter 12: Tinnitus and external sounds (Borka Ceranic).Chapter 13: The effects of blast on the ear (Alan G Kerr).Chapter 14: Interaction of noise, general medical disorders and state of health with hearing (Ulf Rosenhall).Chapter 15: Methodology and value of databases: an individual hearing conservation programme (Esko Toppila, Ilmari Pykko, Jukka Starck, Ann-Christin Johnson and Martti Juhola).Chapter 16: Environmental noise: a contextual public health perspective (Peter Lercher).Chapter 17: Estimating the risk of hearing impairment due to impulse noise exposure (Guido F Smoorenburg).Chapter 18: Occupational noise (Wieslaw J Sulkowski).Chapter 19: Military noise-induced hearing loss (J Attias, AY Duvdevany, I Reshef-Haran, Zilberberg and B Nageris).Chapter 20: The hazardous aspects of music (Rosalyn A Davies).Chapter 21: Organic solvent exposures and occupational hearing loss (Mariola Sliwinska-Kowalska and Ewa Zamyslowska-Szmytke).Chapter 22: Noise hazards in the medical environment (Moshe Chaimoff and Linda M Luxon).Chapter 23: Stress effects of noise (Hartmut Ising and Barbara Kruppa).Chapter 24: Stress and noise - the psychological/physiological perspective and current limitations (Christian Maschke and Karl Hecht).Chapter 25: Noise and cognitive performance in children and adults (Gary W Evans and Staffan Hygge).Chapter 26: Noise and sleep (Barbara Griefahn).Chapter 27: Measurements, standards and laws (Ronald Hinchcliffe).Chapter 28: Preventing hearing loss by sound conditioning (Barbara Canlon and Xianzhi Niu).Chapter 29: Industrial noise control (Terry Bramer).Chapter 30: Hearing protectors (Jukka Starck, Esko Toppila and Ilmari Pyykko).Chapter 31: Audiological rehabilitation programmes and the ICF (KM Holgers and ML Barrenas).Chapter 32: Target groups in prevention of health effects from listening to music (B Pettersson).Chapter 33: Agencies involved with noise (Dietrich H Schwela and Andrew W Smith).Index.
  • (source: Nielsen Book Data)9781861564092 20160528
Noise is an increasing problem in everyday life, and many noise-induced hearing problems are irreversible. This book focuses on all aspects of noise-related problems, including noise effects on stress levels, functional changes after noise-induced cochlear damage, occupational hearing loss and noise conservation problems.
(source: Nielsen Book Data)9781861564092 20160528
Engineering Library (Terman)
xxv, 535 p. : ill. ; 25 cm.
  • Introduction-- Basics of the mechanics of polymers-- PU foam processing and microstructure-- Bead foam processing and microstructure-- Mechanical testing of polymeric foams-- FEA modelling-- Micromechanics of Open-cell foams-- Air flow in open cell foams-- Case study: Seating design-- Case study: Sports and impact mats-- Micromechanics of closed cell foams-- Case study: Transit packaging-- Case study: Running shoe foams-- Case study: Cycle helmets-- Indentation, crack and fracture toughness-- Case study: Motorcycle helmets-- Case study: Hip protectors-- Case study: Thermal sandwich panels-- Creep and creep mechanisms-- Effects of water on polymer mechanics and performance-- Case study: Rugby and Soccer protection.
  • (source: Nielsen Book Data)9780750680691 20160528
This handbook explores the applications of polymer foams, and the properties that make them suitable for so many applications, in the detail required by postgraduate students, researchers and the many industrial engineers and designers who work with polymer foam in industry. It covers the mechanical properties of foams and foam microstructure, processing of foams, mechanical testing and analysis (using Finite element analysis). In addition, it uniquely offers a broader perspective on the actual engineering of foams and foam based (or foam including) products by including nine detailed case studies which firmly plant the theory of the book in a real world context, making it ideal for both polymer engineers and chemists and mechanical engineers and product designers.It provides complete coverage of the mechanical and design aspects of polymer foams from an acknowledged international expert - no other book is available with this breadth making this a plastics engineer's first choice for a single volume Handbook. Polymer foams are ubiquitous in modern life, used everywhere from running shoes to furniture, and this book includes nine extensive case studies covering each key class of application, including biomechanics. It offers a rigorous mechanical and microstructure perspective, plus a computer based chapter: Essential for engineers and designers alike.
(source: Nielsen Book Data)9780750680691 20160528
Engineering Library (Terman)
xxix, 492 p., [16] p. of plates : ill. (some col.) ; 25 cm.
  • Glossary ELEMENTS OF CONTINUUM MECHANICS Biological Transport Processes Basic Momentum, Heat, and Mass Transfer Concepts Conservation Laws Two-Phase Flows Biomechanics Review Summary and Outlook Homework Assignments References BIOFLUID DYNAMICS CONCEPTS Transport Phenomena The Cardiovascular System Homework Problems References ANALYSES OF ARTERIAL DISEASES Vessel Occlusions Aneurysms Examples of Computerized Disease Management Homework Problems References BIOFLUID MECHANICS OF ORGAN SYSTEMS The Lungs The Kidneys The Liver Homework Problems References CASE STUDIES IN BIOFLUID DYNAMICS Prerequisites for Modeling and Simulating Nanodrug Delivery in Microchannels Particle Deposition and Targeting in Human Lung Airways Fluid-Structure Interactions in Stented Aneurysms Project Assignments References APPENDICES Review of Tensor Calculus, Differential Operations, Integral Transformations, and ODE Solutions Single-Phase Field Equations Suitable CFD Solvers Physical Properties References INDEX.
  • (source: Nielsen Book Data)9780849322211 20160528
Requiring only an introductory background in continuum mechanics, including thermodynamics, fluid mechanics, and solid mechanics, "Biofluid Dynamics: Principles and Selected Applications" contains review, methodology, and application chapters to build a solid understanding of medical implants and devices. For additional assistance, it includes a glossary of biological terms, many figures illustrating theoretical concepts, numerous solved sample problems, and mathematical appendices. The text is geared toward seniors and first-year graduate students in engineering and physics as well as professionals in medicine and medical implant/device industries. It can be used as a primary selection for a comprehensive course or for a two-course sequence. The book has two main parts: theory, comprising the first two chapters; and applications, constituting the remainder of the book. Specifically, the author reviews the fundamentals of physical and related biological transport phenomena, such as mass, momentum, and heat transfer in biomedical systems, and highlights complementary topics such as two-phase flow, biomechanics, and fluid-structure interaction. Two appendices summarize needed elements of engineering mathematics and CFD software applications, and these are also found in the fifth chapter. The application part, in form of project analyses, focuses on the cardiovascular system with common arterial diseases, organ systems, targeted drug delivery, and stent-graft implants. Armed with "Biofluid Dynamics", students will be ready to solve basic biofluids - related problems, gain new physical insight, and analyze biofluid dynamics aspects of biomedical systems.
(source: Nielsen Book Data)9780849322211 20160528
Engineering Library (Terman), Science Library (Li and Ma)
ix, 246 p. : ill. ; 28 cm + 1 CD-ROM (4 3/4 in.).
  • Introduction to human anatomy and movement
  • Osteology and the skeletal system
  • Joint motion and the articular system
  • Myology and the muscular system
  • Muscles of movement
  • Mechanics of movement
  • Muscular control of movement and movement assessment
  • Fundamentals of posture, balance, and walking
  • Fundamentals of running, jumping, throwing, kicking, and lifting
  • Analysis of exercise and sport movements
  • Future directions of human movement studies.
Engineering Library (Terman)
xvi, 325 p. : ill. ; 25 cm.
  • Preface to the Third Edition.1. Biomechanics as an Interdiscipline.2. Kinematics.3. Anthropometry.4. Kinetics: Forces and Moments of Force.5. Mechanical Work, Energy, and Power.6. Synthesis of Human Movement-Forward Solutions.7. 3 D Kinematics and Kinetics.8. Muscle Mechanics.9. Kinesiological Electromyography.Appendix A: Kinematic, Kinetic, and Energy Data.Appendix B: Units and Definitions Related to Biomechanical and Electromyographical Measurements.Index.
  • (source: Nielsen Book Data)9780471449898 20160527
This is a thorough update of the classic book on human movement in biomechanics. "Biomechanics and Motor Control of Human Movement, Third Edition" is the thoroughly updated and retitled version of the widely used Biomechanics of Human Movement. Integrating a common set of data and analyses with reliable material on biomechanical techniques, this up to date edition examines techniques used to measure and analyze all body movements as mechanical systems, including such everyday movements as walking. This highly informative and accessible Third Edition treats each limb of the body as a separate segment connected at hinge joints. Actuators replace muscles, and torque motors replace the net effect of all muscles. Descriptions of movements are given as well as examinations of the cause of the movement at kinetic and electromyographic levels. "Biomechanics and Motor Control of Human Movement, Third Edition" features: new material on 3D kinematics and kinetics emphasizing motor control; expanded coverage on image measurement systems; new information on 3D center of mass estimates; models of the kinetics of balance control; the latest research findings on fundamental relationships; and, new biophysical models of EMG detection, as well as standards for recording and reporting. Complete with basic physics principles presented in capsule form for quick reference, "Biomechanics and Motor Control of Human Movement, Third Edition" is an essential resource for students and researchers.
(source: Nielsen Book Data)9780471449898 20160527
Engineering Library (Terman)
xvii, 575 p. : ill. ; 26 cm.
Engineering Library (Terman)

10. On intelligence [2004]

261 p. : ill. ; 21 cm.
  • 1. Artificial intelligence
  • 2. Neural networks
  • 3. The human brain
  • 4. Memory
  • 5. A new framework of intelligence
  • 6. How the cortex works
  • 7. Consciousness and creativity
  • 8. The future of intelligence.
Engineering Library (Terman)
xiii, 298 p. : ill. (some col.) ; 26 cm.
  • Preface-- 1. Introduction-- 2. Cardiovascular and pulmonary physiology and anatomy-- 3. Blood flow in the heart-- 4. The ejection effect of the pumping heart-- 5. Modeling flow and pressure in the systemic arteries-- 6. A cardiovascular model-- 7. A baroreceptor model-- 8. Respiration-- Appendices-- Bibliography-- Index.
  • (source: Nielsen Book Data)9780898715392 20160528
This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors discuss models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation. This is the only book available that analyzes up-to-date models of the physiological system at several levels of detail; both simple 'real-time' models that can be directly used in larger systems, and more detailed 'reference' models that show the underlying physiological mechanisms and provide parameters for and validation of simpler models. The book also covers two-dimensional modeling of the fluid dynamics in the heart and its ability to pump, and includes a discussion of modeling wave-propagation throughout the systemic arteries.
(source: Nielsen Book Data)9780898715392 20160528
Engineering Library (Terman)
171 p. : ill. ; 24 cm.
  • Preface (P. B. Pascolo).- The Biomedical Engineering Education in Italy (M. Bracale).- Video-Fluoroscopy Based Investigation of Intervertebral Kinematics for Sport Medicine Application (M. Sansone, P. Bifulco, M. Cesarelli, M. Bracale).- Computation of Rigid Body Motion Parameters from Video-Based Measurements (U. Tarantino, D. Perugia, G. Campanacci, E. Pennestri).- Mechanical Ventilators and Ventilator Testers (G. Belforte, G. Eula, T. Raparelli).- Cardiovascular and Metabolic Effort in a World Class Sailor at Different Wind Velocities (T. Princi, C. Capelli, G. Delbello, L. Nevierov).- A mechanical model of the biceps brachii muscle (M. Gatti, P. Pascolo, N. Rovere, M. Saccavini).- Evaluation of Quadriceps Muscles in Anterior Knee Pain: a Possible Sport Medicine Application (M. Cesarelli, P. Bifulco, M. Sansone, M. Romano, M. Bracale).- A Neural-based Model for the Control of the Arm During Planar Ballistic Movements (S. Conforto, M. Schmid, G. Gallo, T. D'Alessio, N. Accornero, M. Capozza).- The Relevance of Auditory Information in Optimizing Hammer Throwers Performance (T. Agostini, G. Righi, A. Galmonte, P. Bruno).- Complex Test of Cycling Performance (Z. Knoll, L. Kocsis, I. Gyore, R. Kiss).- Foot-Floor Interaction in Classic Dancers (C. Giacomozzi, S. Marucci, V. Macellari, L. Uccioli, E. D'Ambrogi).- Gait Pattern of Professional Fencers (Z. Knoll, L. Kocsis, R. Kiss).- Gait Alterations on Carriers of Bilateral Arthroplasty of the Hip Suffering from LES: Clinical, Radiographic and Instrumental Evaluation with Gait Analysis (M. Bacchini, C. Rovacchi, M. Rossi).- Quantification with Gait Analysis of Biomechanic Risk Protofactors Regarding the Patellar Tendinosis in Athletes with Varus Knee (M. Bacchini, M. Rossi).- Teaching a Robot woth Human Natural Movements (G. Magenes, E. Secco).- Numerical Simulation of Motorcycles Crash Test (L. Fabbri, G. Franceschini, F. Mastrandrea).- Biomechanical Power Analysis in Nordic and Alpine Skiing (A. Schwirtz, D. Hahn, A. Huber, A. Neubert, F. Tusker).- 3-D Kinematic and Kinetic Analysis of G-Slalom at Valbadia Cup-Race in 2002 (R. Pozzo, A. Canclini, C. Cotelli, G. Baroni).
  • (source: Nielsen Book Data)9783211212103 20160528
On XXI Winter Universiads 2003, CISM offered its scientific contribution by hosting a conference on mechanics applied to sports and, in general, to human movement. The conference was conceived as a chance to overview experiences gained from several operators working on different aspects of biomechanics. The reader will face in these proceedings bioengineering aspects, control issues, techniques for the optimization of human performances as well as methods for the improvement of athletic equipments and devices. Biomechanical data and signal processing, biomaterials and robotics complete the proposed framework. Some works were consistent with the fact that 2003 was designated as European Year of Disabled People. Indeed, many innovations in sport and biomechanics could suggest interesting rehabilitative applications and a better prevention of some pathologies due to the exercise of some normal activities like professional cycling.
(source: Nielsen Book Data)9783211212103 20160528
Engineering Library (Terman)
xi, 331 p. : ill. ; 29 cm.
  • Methods to examine variability in human movement-- methods to examine co-ordination and stability in human movement-- advanced methods for data analysis in human movement.
  • (source: Nielsen Book Data)9780736044677 20160528
This text is designed for both students and professionals dealing with measurement issues in human movement. It explains methods for analysing human movement; presents techniques and methods in a tutorial fashion; provides step-by-step examples for each method and technique; and more.
(source: Nielsen Book Data)9780736044677 20160528
Engineering Library (Terman)
154 p. : ill. ; 25 cm.
  • Chapter 1: Wood as an engineering material Advantages and disadvantages compared with other materials-- Structure of the material and its effect on strength in various loading modes-- Problems of joining, and how they are overcomes-- Problems of dimensional stability, and how they are overcome-- Use in the form of sheet material-- Stiffness of boxes fabricated from orthotropic sheets such as plywood-- Prevention of deterioration-- Further reading Chapter 2: Uniform stress - A design rule for biological load carriers Introduction-- Axiom of uniform stress-- Optimisation methods-- Conclusions Chapter 3: Nature and shipbuilding The jungle of the sea-- Wooden shipbuilding: the basic problem-- Shipbuilding-related wood properties Chapter 4: The structural efficiency of trees Introduction-- Loading conditions-- Adaptive growth-- Optimal structural features-- Optimal material features-- Case study on adaptive growth-- Research-- Conclusion Chapter 5: Application of the homeostasis principle to expand Gaudi's funicular technique Introduction-- The funicular model-- The Homeostatic Model-- Conclusions-- Final reflection Chapter 6: Bones: the need for intrinsic material and architectural design Introduction-- Variations in lamellar properties within osteons-- Variations in bone properties with age and between individuals-- Variations in lamellar properties in remodelled equine bone-- Discussion and Conclusions Chapter 7: Restoration of biological and mechanical function in orthopaedics: A role for biomimesis in tissue engineering Introduction-- Tissue engineering-- Tissue engineering scaffolds-- Natural biomaterials and skeletons-- Biomimetic materials chemistry-- Gene manipulation in tissue engineering-- Conclusion Chapter 8: Design in nature Introduction-- Genotypic/predictive - safe life-- Phenotypic/adaptive-- Cross-over from prediction to adaptation-- Behavioural-- Implications for Biomimesis.
  • (source: Nielsen Book Data)9781853129469 20160527
This book comprises a study of the two great organic solids in Nature, namely wood and bone. The common scientific laws which act in parallel for both natural and man-made materials are detailed here as wood and bone are studied in their natural structural environment as well as in the fields of engineering structural analysis and medical analysis. The relationship between them enables wood to be used in engineering structures and man-made materials to be used as scaffolding for tissue restoration in the human environment. The 'two-way traffic' relationship explored in this volume is termed biomimesis, a modern development of the ancient Greek concept of mimesis - the man-made imitation of nature.
(source: Nielsen Book Data)9781853129469 20160527
Engineering Library (Terman)
xxii, 195 p. : ill. ; 28 cm.
  • 1. From Sequence to Structure:.Overview: Protein Function and Architecture.Amino Acids.Genes and Proteins.The Peptide Bond.Bonds that Stablize Folded Proteins.Importance and Determinants of Secondary Structure.Properties of the Alpha Helix.Properties of the Beta Sheet.Prediction of Secondary Structure.Folding.Tertiary Structure.Membrane Protein Structure.Protein Stability 1: Weak Interactions and Flexibility.Protein Stability 2: Post-Translational Modifications.The Protein Domain.The Universe of Protein Structures.Protein Motifs.Alpha Domains and Beta Domains.Alpha/Beta, Alpha+Beta and Cross-Linked Domains.Quaternary Structure: General Principles.Quaternary Structure: Intermolecular Interfaces.Quaternary Structure: Geometry.Protein Flexibility.2. From Structure to Function:.Overview: The Structural Basis of Protein Function.Recognition, Complementarity and Active Sites.Flexibility and Protein Function.Location of Binding Sites.Nature of Binding Sites.Functional Properties of Structural Proteins.Catalysis: Overview.Active-site Geometry.Proximity and Ground-State Destabilization.Stabilization of Transition States and Exclusion of Water.Redox Reaction.Addition/Elimination, Hydrolysis and Decarboxylation.Active-Site Chemistry.Cofactors.Multi-Step Reactions.Multifunctional Enzymes.Multifunctional Enzymes with Tunnels.3. Control of Protein Function:.Overview: Mechanisms of Regulation.Protein Interaction Domains.Regulation by Location.Control by pH and Redox Environment.Effector Ligands: Competitive Binding and Cooperativity.Effector Ligands: Conformational Change and Allostery.Protein Switches Based on Nucleotide Hydrolysis.GTPase Switches: Small Signaling G proteins.GTPase Switches: Signal Relay by Heterotrimeric GTPases.Gtpase Switches: Protein Synthesis.Motor Protein Switches.Regulation by Degradation.Control of Protein Function by Phosphorylation.Regulation of Signaling Protein Kinases: Activation Mechnism.Regulation of Signaling Protein Kinases: Cdk Activation.Two-Component Signaling Systems in Bacteria.Control by Proteolysis: Activation of Precursors.Protein Splicing: Autoproteolysis by Inteins.Glycosylation.Protein Targeting by Lipid Modification.Methylation, N-acetylation, Sumoylation and Nitrosylation.4. From Sequence to Function:.Overview: From Sequence to Function in the Age of Genomics.Sequence Alignment and Comparison.Protein Profiling.Deriving Function from Sequence.Experimental Tools for Probing Protein Function.Divergent and Convergent Evolution.Structure from Sequence: Homology Modeling.Structure from Sequence: Profile-Based Threading and "Rosetta".Deducing Function from Structure: Protein Superfamilies.Strategies for Identifying Binding Sites.Strategies for Identifying Catalytic Residues.TIM Barrels: One Structure with Diverse Functions.PLP Enzymes: Diverse Structures with One Function.Moonlighting: Proteins with More Than One Function.Chameleon Sequences: One Sequence with More than One Fold.Prions, Amyloids and Serpins: Metastable Protein Folds.Functions for Uncharacterized Genes: Galactonate Dehydratase.Starting from Scratch: A Gene Product of Unknown Function.5. Structure Determination:.The Interpretation of Structural Information.Structure Determination by X-Ray Crystallography and NWR.Quality and Representation of Crystal and NMR Structures.
  • (source: Nielsen Book Data)9781405119221 20160527
  • 1. From Sequence to Structure-- 2. From Structure to Function-- 3. Control of Protein Function-- 4. From Sequence to Function: Case Studies in Structural and Functional Genomics-- 5. Structure Determination.
  • (source: Nielsen Book Data)9780199556847 20160528
"Protein Structure and Function" considers the key concepts of protein structure and function and the relationship between sequence, structure and function with clear, concise explanations and full colour illustrations. It is written by two outstanding names in the field, Gregory Petsko and Dagmar Ringe. It considers the principles of protein structure and folding, functional properties of proteins and regulation of protein function, and introduces the basic principles whereby structure and function are deduced from sequence. This work is fully up-to-date with emphasis on what sequence can tell you about structure and function. It is ideal for undergraduates and graduates studying the fundamental principles of protein structure and function in departments of biochemistry and molecular biology, and working scientists needing an up-to-date introduction to the field.All 240 illustrations from "Protein Structure and Function" are available on the web as jpgs and downloadable tifs for teaching.
(source: Nielsen Book Data)9781405119221 20160527
Intended for upper-level undergraduate and beginning graduate students, this primer introduces the general principles of protein structure, folding, and function and explains the conceptual basis for inferring structure and function from genomic sequence. Employing a modular design, chapters are div.
(source: Nielsen Book Data)9780878936632 20160527
How does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein? Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure integrates text, illustrations, definitions, and literature references for each topic into one double-page spread, bringing to the student's fingertips all the tools that they need to master that topic. Online Resource Centre The Online Resource Centre features figures from the book available to download, for registered adopters of the book.
(source: Nielsen Book Data)9780199556847 20160528
Engineering Library (Terman)
x, 309 p. : ill. ; 29 cm.
  • Part I Kinematics-- Chapter 1. Biomechanics Analysis Techniques: A Primer-- Chapter 2. Planar Kinematics-- Chapter 3. Three-Dimensional Kinematics-- Part II Kinetics-- Chapter 4. Body Segment Parameters-- Chapter 5. Forces and Their Measurement-- Chapter 6. Two-Dimensional Inverse Dynamics-- Chapter 7. Energy, Work, and Power-- Chapter 8. Three-Dimensional Kinetics-- Part III Additional Techniques-- Chapter 9. Electromyographic Kinesiology-- Chapter 10. Muscle Modeling-- Chapter 11. Computer Simulation of Human Movement-- Chapter 12. Signal Processing.
  • (source: Nielsen Book Data)9780736039666 20160528
Research Methods in Biomechanics explains how to collect, analyse and interpret various forms of biomechanical data. It covers an extensive range of topics in biomechanics, including inverse dynamics, dynamometry, electromyography, modelling and simulation. The text shows how the laws of motion are applied to complex human movements, including body segment analysis.
(source: Nielsen Book Data)9780736039666 20160528
Engineering Library (Terman)
ix, 470 p. : ill. ; 29 cm.
  • Part 1: Foundations of Human Movement Chapter 1:Material Properties Chapter 2: Skeletal Considerations for Movement Chapter 3: Muscular Considerations for Movement Chapter 4: Neurological Considerations for Movement Part 2: Functional Anatomy Chapter 5: The Upper Extremity Chapter 6: The Lower Extremity Chapter 7: The Trunk Part 3: Mechanical Analysis of Human Movement Chapter 8: Linear Kinematics Chapter 9: Angular Kinematics Chapter 10: Linear Kinetics Chapter 11: Angular Kinetic.
  • (source: Nielsen Book Data)9780781734059 20160528
"Biomechanical Basis of Human Movement" integrates basic anatomy, physics, calculus, and physiology for the study of human movement. The book provides a uniquely quantitative approach to biomechanics, and is organized into three parts: Foundations of Human Movement, Functional Anatomy, and Mechanical Analysis of Human Motion. New to this edition include: basic mathematics information, increased practical applications, and a new chapter on emphasizing techniques for measuring the strength of human tissue.
(source: Nielsen Book Data)9780781734059 20160528
Engineering Library (Terman)
xxii, 597 p. : ill. (some col.) ; 29 cm.
  • Section I: Essential Topics of Kinesiology. Fundamental Principles of Kinesiology. The Structure and Basic Function of Joints. Muscles: The Ultimate Force Generator. Basic Biomechanical Principles of Kinesiology. Appendix 1: Glossary of Key Terms. Section II: The Kinesiology of the Upper Extremity. The Shoulder Complex. The Elbow. The Wrist. The Hand. Appendix 2: Attachments and Innervation of the Musclers of the Upper Extremity. Section III: The Kinesiology of the Axial Skeleton. The Axial Skeleton - Part 1: Osteology and Arthrology. The Axial Skeleton - Part 2: Muscle and Joint Interaction. The Axial Skeleton - Part 3: The Temporomandibular Joint and the Mechanics of Breathing. Appendix 3: Attachments and Innervation of the Muscles of the Axial Skeleton. Section IV: The Kinesiology of the Lower Extremity. The Hip. The Knee. The Ankle and Foot. The Kinesiology of the Human Gait. Appendix 4: Attachments and Innervation of the Muscles of the Lower Extremity. Index.
  • (source: Nielsen Book Data)9780815163497 20160528
The link between structure and function of the musculoskeletal system is clarified and explained in this complete guide to clinical kinesiology. "Kinesiology of the Musculoskeletal System" is the most comprehensive, research-based, reader-friendly text on kinesiology ever published. Beautifully and abundantly illustrated in two-colour, this dynamic, accessible resource presents complex scientific information in an approach designed to draw the reader in and explore the fundamental principles of kinesiology of the trunk and extremities as well as in relation to joints, muscles, and biomechanics.
(source: Nielsen Book Data)9780815163497 20160528
Engineering Library (Terman)
xvii, 653 p. : ill. ; 24 cm.
  • External contact forces-- statics of multilink serial chains - transformational analysis-- statics of multilink chains - stability of equilibrium-- inertial properties of the human body-- joint torques and forces - the inverse problem of dynamics-- mechanical work and energy in human movement. Appendices: inertial properties of cadavers-- inertial properties measured in living subjects-- geometric modeling of human body segments.
  • (source: Nielsen Book Data)9780736037785 20160528
Written by a recognized authority on the subject, "Kinetics of Human Motion" is the sequel and companion to the 1998 text "Kinematics of Human Motion". Biomechanics expert Vladimir Zatsiorsky has written this book to be an indispensable reference for human movement professionals. Although biomechanical analysis of human motion can be conducted on different structural levels, this book focuses on the examination of forces that create entire body motion, thereby developing the biomechanical knowledge of the reader. This text is advanced and assumes some knowledge of algebra and calculus, yet the emphasis is clearly on understanding physical concepts, not mathematical formulae. The book features helpful refreshers of basic mathematical concepts and kinesiology and other movement-related topics to facilitate reader comprehension of the topics presented. The illustrations and equations help to clarify and reemphasize the main concepts; it also contains review problems, applied research problems, end-of-chapter questions, and references throughout. For a more rounded understanding of the concepts, each chapter includes "From the Literature" elements, which support the theories discussed while offering other viewpoints. This is the second in a three-book series that will cover the entire range of biomechanics of human motion.
(source: Nielsen Book Data)9780736037785 20160528
Engineering Library (Terman)
xix, 556 p. : ill. ; 29 cm.
  • Part 1 The force-motion relationship: describing motion-- movement forces-- analyzing movement-- running, throwing and jumping. Part 2 The motor system: single joint system components-- single joint system function-- multi-joint systems. Part 3 Adaptability of the motor system: acute adaptations.
  • (source: Nielsen Book Data)9780736002516 20160528
The third edition of this foundation text - based on the concepts of the original text, "Neuromechanical Basis of Kinesiology" - features a new title that reflects its application to a broader array of human movement capabilities. This text expands on previous editions and retains popular features from the original text. Although expanded and updated, it still integrates biomechanics and neurophysiology to provide a theoretical framework for the study of human movement. This edition presents a more systematic and practical approach to problem solving, as well as updated content, and a CD-ROM support package for lecturers. Features include: bulleted summaries of each part which recap important learning points for students; a glossary of terms and three appendices with conversion factors and other background information; specific illustrations of the neuromechanics behind sport and rehabilitation movements; checklists to help students and teachers focus quickly; examples in each chapter, including figures, tables and equations; and more than 1500 updated references, plus a suggested reading list at the end of each chapter.
(source: Nielsen Book Data)9780736002516 20160528
Engineering Library (Terman)