• Predictions of Protein-Protein Interactions at the Atomic Scale.- An Infrared Study of Fibril Formation Insulin from Different Sources.- Some Basic Biomolecular NMR from Protein Structure Determination.- Solid State NMR for Studying Membrane Proteins.- Protein Complexes in SUMO Signaling. -Mass Spectrometry and Glycomics.- Mechanisms of Supramolecular Assembly Exemplified by Microtubules and Amyloid Fibril Formation.- Hepatitis B-Virus (HBV): The Life-cycle and Assembly of a Complex Virus.- Photo-oxidative Stress in the Presence of a Water-soluble Derivative of C60: ESR and AFM Assays.- Functional EPR Spectroscopy and Imaging of Nitroxides.- Novel Leads for Selective Antibiotics against Shigellosis by Virtual Screening, Cristallography and Synthesis.- Virtual Ligand Screening: A Method to Discover New Drug Leads.- From Solid State to Bio-complexity: On the Emerging Science of Emergence.- MR Spectroscopy and the Early Detection of Cancer in Human Subjects.- Microarray and Single Cell Analysis Techniques in Bio-medical Fields.- SOS Hypothesis and the Emergences of Integrative Biology.
• (source: Nielsen Book Data)

The book is based on International Summer Schools on Biophysics held in Croatia which, contrary to other workshops centered mainly on one topic or technique, has very broad scope providing advanced training in areas related to biophysics. This volume presents papers in the field of biophysics for studying biological phenomena by using physical methods and/or concepts. Its scope should be of interest for students at doctoral or postdoctoral level and to experienced scientists.
(source: Nielsen Book Data)

• 1. Structural Basis of Protein Synthesis.-
• 2. The Relationship Between Protein Sequence, Structure and Function: Protein Function Prediction.-
• 3. Differences in Binding of Stereoisomers to Protein Active Sites.-
• 4. Analytical Centrifugation: Looking at Aggregation in Free Solution.-
• 5. Time Resolved Protein Fluorescence. Application to Multi-Tryptophan Proteins.-
• 6. Novel (Bio)chemical and (Photo)physical Probes for Imaging Living Cells.-
• 7. Observing Structure and Dynamics of Membrane Proteins by High-resolution Microscopy.-
• 8. A 2D-Infrared Study of Human Lipoproteins.-
• 9. An Introduction to Biological Solid State NMR.-
• 10. Multi-Frequency EPR Spectroscopy Studies of the Structure and Conformational Changes of Site-Directed Spin Labelled Membrane Proteins.-
• 11. Identification of Protein Structure and its Modifications by Electrospray Mass Spectrometry in Proteomics.-
• 12. A Microscopic Study of Disorder-Order Transitions in Molecular Recognition of Unstructured Proteins: Hierarchy of Structural Loss and the Transition State Determination from Monte Carlo Simulations of P27KIP1 Protein Coupled Unfolding and Unbinding.-
• 13. Computational Detection of the Binding Site Hot Spot and Predicting Energetics of Ligand Binding at the Remodeled Human Growth Hormone-Receptor Interface Using a Hierarchy of Molecular Docking and Binding Free Energy Approaches.-
• 14. Molecular and Cellular Levels of Biological Evolution.- Index.
• (source: Nielsen Book Data)

This volume covers some powerful biophysical methods, such as analytical centrifugation, mass spectrometry, fluorescence spectroscopy, electron spin resonance and nuclear magnetic resonance, for the study of complex biological structures, and discusses useful physical concepts as applied to biological and biochemical systems. Case-orientated studies concentrating on particular methodologies are presented and examples are given, addressing some of the most important aspects of structure-function relationship in biological assemblies. Biophysics nowadays collaborates closely with molecular biology and bioinformatics and this is also demonstrated in this book. The book will be of interest both to experienced researchers wishing to widen their insight into molecular structure and function, and to younger scientists at the doctoral and postdoctoral level interested in the molecular nature of fundamental biological entities and phenomena.
(source: Nielsen Book Data)

• 1. Aspect of the Evolution of Biophysics: Polyelectrolytes and the Weizman-- H. Eisenberg.
• 2. Analytical Centrifugation: Looking at Aggregation in Free Solution-- P.J.G. Butler.
• 3. Mass Spectrometry of Peptides and Proteins
• Principles and Features of Electrospray/Ionization-Mass Spectrometry (ESI-MS) and Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry (MALDI-MS)-- K. Strupat, W. Metelmann.
• 4. Adsorption Kinetics of Low Density Lipoprotein onto a Hydrophobic-Hydrophilic Gradient Surface-- V. Hlady.
• 5. Fluorescence Spectroscopic Studies on Structure and Function of Lipolytic Enzymes-- A. Hermetter, et al.
• 6. Infrared Spectroscopy of Lipoproteins-- X. Coto, J.L.R. Arrondo.
• 7. New Approaches in Spin Labeling and Spin Trapping. Part One: ESR Studies of Local Chemical Environment-- V.V. Khramtso
• v. 8. New Approaches in Spin Labeling and Spin Trapping. Part Two: NMR Detects Free Radicals-- V.V. Khramtsov, et al.
• 9. Free Radical Intermediates of Drugs and Xenobiotics-- L.J. Berliner, H. Fujii.
• 10. In vivo Detection of Nitric Oxide: Combining EPR and NMR-- L.J. Berliner, H. Fujii.
• 11. On Biological Information-- M. Eigen.
• 12. Accuracy versus Efficacy in Biological Processes-- M. Radman.
• 13. Towards a Memory-Based Interpretation of Proteome Data-- J. Murvai, et al.
• 14. Modelling DNA Structure from Sequence-- K. Vlahovicek, S. Pongor.
• 15. Nonlinear Dynamics in the Binary DNA/RNA Coding Problem-- M. Martinis.
• 16. High Density DNA and Protein Arrays, Generation and Applications-- D.J. Cahill.
• 17. Mechanisms of Synaptic Plasticity in the Brain-- K. Krnjevic. Subject Index.
• (source: Nielsen Book Data)

This book is the proceedings of the 7th International Summer School on Biophysics: Supramolecular Structure and Function, held September 14-26, 2000, in Rovinj, Croatia. An enormous amount of new knowledge on the molecular basis of biological phenomena has emerged in the rapidly expanding field of biophysics. The principles and methods of modern biophysics now provide a strong foundation for all of the biosciences, and serve as a rational common language for scientists from various disciplines.The series of books on Supramolecular Structure and Function was inspired by the International Summer School on Biophysics, established under the sponsorship of IUPAB, UNESCO, and ICGEB, held in Rovinj, in 2001, and follows the successful interdisciplinary approach. This volume covers some powerful methods, such as analytical centrifugation, mass spectrometry, fluorescence spectroscopy, infrared spectroscopy, electron spin resonance and nuclear magnetic resonance, for the study of complex biological structures, and discusses useful physical concepts as applied to biological and biochemical systems.Case-orientated studies concentrating on particular methodologies are presented and examples are given, addressing some of the most important aspects of structure-function relationship in biological assemblies. Biophysics nowadays collaborates closely with molecular biology and bioinformatics as well as with neurosciences, and this is also demonstrated in this book. The book should be of interest both to experienced researchers wishing to widen their insight into molecular structure and function, and to younger scientists at the doctoral and postdoctoral level interested in the molecular nature of fundamental biological entities and phenomena.
(source: Nielsen Book Data)

• 1.Aspects of the Evolution of Biophysics: Polyelectrolytes and the Weizmann
• 2.Analytical Centrifugation: Looking at Aggregation in Free Solution
• 3.Mass Spectrometry of Peptides and Proteins
• Principles and Features of Electrospray/Ionization-Mass Spectrometry (ESI-MS) and Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry (MALDI-MS)
• 4.Adsorption Kinetics of Low Density Lipoprotein onto a Hydrophobic-Hydrophilic Gradient Surface
• 5.Fluorescence Spectroscopic Studies on Structure and Function of Lipolytic Enzymes
• 6.Infrared Spectroscopy of Lipoproteins
• 7.New Approaches in Spin Labeling and Spin Trapping. Part One: ESR Studies of Local Chemical Environment
• 8.New Approaches in Spin Labeling and Spin Trapping. Part Two: NMR Detects Free Radicals
• 9.Free Radical Intermediates of Drugs and Xenobiotics
• 10.In vivo Detection of Nitric Oxide: Combining EPR and NMR
• 11.On Biological Information
• 12.Accuracy versus Efficacy in Biological Processes
• 13.Towards a Memory-Based Interpretation of Proteome Data
• 14.Modelling DNA Structure from Sequence
• 15.Nonlinear Dynamics in the Binary DNA/RNA Coding Problem
• 16.High Density DNA and Protein Arrays, Generation and Applications
• 17.Mechanisms of Synaptic Plasticity in the Brain.

This book is the proceedings of the 7th International Summer School on Biophysics: Supramolecular Structure and Function, held September 14-26, 2000, in Rovinj, Croatia. An enormous amount of new knowledge on the molecular basis of biological phenomena has emerged in the rapidly expanding field of biophysics. The principles and methods of modern biophysics now provide a strong foundation for all of the biosciences, and serve as a rational common language for scientists from various disciplines. The series of books on Supramolecular Structure and Function was inspired by the International Summer School on Biophysics, established under the sponsorship of IUPAB, UNESCO, and ICGEB, held in Rovinj, in 2001, and follows the successful interdisciplinary approach. This volume covers some powerful methods, such as analytical centrifugation, mass spectrometry, fluorescence spectroscopy, infrared spectroscopy, electron spin resonance and nuclear magnetic resonance, for the study of complex biological structures, and discusses useful physical concepts as applied to biological and biochemical systems. Case-orientated studies concentrating on particular methodologies are presented and examples are given, addressing some of the most important aspects of structure-function relationship in biological assemblies. Biophysics nowadays collaborates closely with molecular biology and bioinformatics as well as with neurosciences, and this is also demonstrated in this book. The book should be of interest both to experienced researchers wishing to widen their insight into molecular structure and function, and to younger scientists at the doctoral and postdoctoral level interested in the molecular nature of fundamental biological entities and phenomena.