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Online 1. Single-molecule and super-resolution in living cells [2011]
- Lee, Hsiao-lu.
- Dec. 2011.
- Description
- Book — online resource (xiv, 228 pages) : illustrations (some color)
- Summary
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Since the first successful detection single molecules over two decades ago, single-molecule spectroscopy has developed into a burgeoning field with a wealth of experiments at room temperature and inside living cells. Probing asynchronous and heterogeneous populations in situ, one molecule at a time, is not only desirable, but critical for many biological questions. Further, super-resolution imaging based on sequential imaging of sparse subsets of single molecules, has seen explosive growth within the last five years. This dissertation describes both the application of live-cell single-molecule imaging as an answer to important biological questions, and development and validation of fluorescent probes for targeted super-resolution imaging.
- Also online at
Medical Library (Lane)
Medical Library (Lane) | Status |
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(no call number) | Unknown |
- Lee, Hsiao-lu.
- 2011.
- Description
- Book — 1 online resource.
- Summary
-
Since the first successful detection single molecules over two decades ago, single-molecule spectroscopy has developed into a burgeoning field with a wealth of experiments at room temperature and inside living cells. Probing asynchronous and heterogeneous populations in situ, one molecule at a time, is not only desirable, but critical for many biological questions. Further, super-resolution imaging based on sequential imaging of sparse subsets of single molecules, has seen explosive growth within the last five years. This dissertation describes both the application of live-cell single-molecule imaging as an answer to important biological questions, and development and validation of fluorescent probes for targeted super-resolution imaging.
- Also online at
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Special Collections
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University Archives | Request on-site access (opens in new tab) |
3781 2011 L | In-library use |