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• Structure and properties
• bonding and molecular structure
• chemical reactivity and organic reactions
• alkanes
• cycloalkanes
• stereochemistry
• alkenes
• alkyl halides
• alkynes, dienes and orbital symmetry
• aromaticity and benzene
• aromatic substitution, arenes
• spectroscopy and structure proof
• alcohols and thiols
• ethers, epoxides, glycols and thioethers
• aldehydes and ketones
• carboxylic acids
• acid derivatives
• carbanion-enolates and enols
• amines
• phenols and their derivatives
• aromatic heterocyclic compounds
• amino acids, peptides and proteins
• carbohydrates.
• (source: Nielsen Book Data)

Master organic chemistry with "Schaum's" - the high-performance solved-problem guide. It will help you cut study time, hone problem-solving skills, and achieve your personal best on exams! Students love "Schaum's Solved Problem Guides" because they produce results. Each year, thousands of students improve their test scores and final grades with these indispensable guides. Get the edge on your classmates. Use "Schaum's"! If you don't have a lot of time but want to excel in class, use this book to: brush up before tests; study quickly and more effectively; and, learn the best strategies for solving tough problems in step-by-step detail. Review what you've learned in class by solving thousands of relevant problems that test your skill.Compatible with any classroom text, "Schaum's Solved Problem Guides" let you practice at your own pace and remind you of all the important problem-solving techniques you need to remember fast! And "Schaum's" are so complete, they're perfect for preparing for graduate or professional exams. Inside you will find: 3000 solved problems with complete solutions, the largest selection of solved problems yet published on this subject; an index to help you quickly locate the types of problems you want to solve; problems like those you'll find on your exams; techniques for choosing the correct approach to problems; and, guidance toward the quickest, most efficient solutions.If you want top grades and thorough understanding of organic chemistry, this powerful study tool is the best tutor you can have! Chapters include: Structure and Properties; Bonding and Molecular Structure; Chemical Reactivity and Organic Reactions; Alkanes; Cycloalkanes; Stereochemistry; Alkenes; Alkyl Halides; Alkynes, Dienes, and Orbital Symmetry; Aromaticity and Benzene; Aromatic Substitution, Arenes; Spectroscopy and Structure Proof; Alcohols and Thiols; Ethers, Epoxides, Glycols, and Thioethers; Aldehydes and Ketones; Carboxylic Acids; Acid Derivatives; Carbanion-Enolates and Enols; Amines; Phenols and Their Derivatives; Aromatic Heterocyclic Compounds; Amino Acids, Peptides, and Proteins; and, Carbohydrates.
(source: Nielsen Book Data)

• Alkylation of Enolates and Other Carbon Nucleophiles.- Reactions of Carbon Nucleophiles with Carbonyl Groups.- Functional Group Interconversion, Protection and Deprotection.- Electrophilic Additions to Carbon-Carbon Multiple Bonds.- Reduction of Carbon-Carbon Multiple, Carbonyl Groups, and Other Functional Groups.- Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations.- Organometallic Compounds of the Group I, II, and III Metals.- Reactions Involving the Transition Metals.- Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin.- Reactions Involving Carbocations, Carbenes, and Radicals as Intermediates.- Aromatic Substitution Reactions.- Oxidations.- Planning and Execution of Multistep Syntheses.
• (source: Nielsen Book Data)

• Chemical Bonding and Structure.- Stereochemistry, Conformation and Stereoselectivity.- Structural Effects on Stability and Reactivity.- Nucleophilic Substitution.- Polar Addition and Elimination Reactions.- Carbanions and Other Carbon Nucleophiles.- Addition, Condensation and Substitution Reactions of Carbonyl Compounds.- Aromaticity.- Aromatic Substitution.- Concerted Pericyclic Reactions.- Free Radical Reactions.- Photochemistry.
• (source: Nielsen Book Data)

Since its original appearance in 1977, Advanced Organic Chemistry has maintained its place as the premier textbook in the field, offering broad coverage of the structure, reactivity and synthesis of organic compounds. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed. The two-part fifth edition has been substantially revised and reorganized for greater clarity. Among the changes: Updated material reflecting advances in the field since 2001??'s Fourth Edition, especially in computational chemistry; A companion Web site provides digital models for study of structure, reaction and selectivity; Solutions to the exercises provided to instructors online. The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. Together with Part A: Structure and Mechanisms, the two volumes are intended to provide the advanced undergraduate or beginning graduate student in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry.
(source: Nielsen Book Data)
The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.
(source: Nielsen Book Data)

• Alkylation of Nuclephilic Carbon
• Reactions of Carbon Nucleophiles with Carbonyl Groups
• Functional Group Interconversion by Nucleophilic Substitution
• Electrophilic Additions to Carbon-Carbon Multiple Bonds
• Reduction of Carbonyl and Other Functional Groups
• Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations
• Organometallic Compounds of the Group I and II Metals
• Reactions Involving the Transition Metals
• Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon and Tin
• Reactions Involving Carbocations, Carbenes and Radicals as Reactive Intermediates
• Aromatic Substitution Reactions
• Oxidations
• Planning and Execution of Multi-Step Syntheses.
• (source: Nielsen Book Data)

• Chemical bonding and structure
• stereochemical principles
• conformational, steric and stereoelectronic effects
• study and description of organic reaction mechanisms
• nucleophilic substitution
• polar addition and elimination reactions
• cabanions and other nucleophilic carbon species
• reactions of carbonyl compounds
• aromaticity
• aromatic substitution
• concerted pericyclic reactions
• free-radical reactions
• photochemistry.
• (source: Nielsen Book Data)

• Preface to the Fourth Edition. Part A: Structure and Mechanisms.
• 1. Chemical Bonding and Structure.
• 2. Stereochemical Principles.
• 3. Conformational, Steric, and Stereoelectronic Effects.
• 4. Study and Description of Organic Reaction Mechanisms.
• 5. Nucleophilic Substitution.
• 6. Polar Addition and Elimination Reactions.
• 7. Cabanions and Other Nucleophilic Carbon Species.
• 8. Reactions of Carbonyl Compounds.
• 9. Aromaticity.
• 10. Aromatic Substitution.
• 11. Concerted Pericyclic Reactions.
• 12. Free-Radical Reactions.
• 13. Photochemistry. References. Index.
• (source: Nielsen Book Data)

Since its original appearance in 1977, "Advanced Organic Chemistry" has found wide use as a text providing broad coverage of the structure, reactivity and synthesis of organic compounds. The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types, including nucleophilic substitution, addition reactions, carbonyl chemistry, aromatic substitution and free radical reactions. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed. The Fourth Edition updates certain topics that have advanced rapidly in the decade since the Third Edition was published, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis. The two parts stand alone, although there is considerable cross-referencing. Part A emphasizes quantitative and qualitative description of structural effects on reactivity and mechanism. Part B emphasizes the most general and useful synthetic reactions. The focus is on the core of organic chemistry, but the information provided forms the foundation for future study and research in medicinal and pharmaceutical chemistry, biological chemistry and physical properties of organic compounds. The New Revised 5th Edition will be available shortly.
(source: Nielsen Book Data)
The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. In the decade since the publication of the third edition, major advances have been made in the development of efficient new methods, particularly catalytic processes, and in means for control of reaction stereochemistry. This volume assumes a level of familiarity with structural and mechanistic concepts comparable to that in the companion volume, Part A, "Structures and Mechanisms". Together, the two volumes are intended to provide the advanced undergraduate or beginning graduate student in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry. The New Revised 5th Edition will be available shortly.
(source: Nielsen Book Data)

• General introduction Safety Safety is your primary responsibility Safe working practice Safety risk assessments Common hazards Accident and emergency procedures Bibliography Keeping records of laboratory work Introduction The laboratory notebook Keeping records of data Some tips on report and thesis preparation References Equipping the laboratory and the bench Introduction Setting up the laboratory General laboratory equipment The individual bench Equipment for parallel experiments Equipment for controlled experimentation Purification and drying of solvents Introduction Purification of solvents Drying agents Drying of solvents References Reagents: Preparation, purification, and handling Introduction Classification of reagents for handling Techniques for obtaining pure and dry reagents Techniques for handling and measuring reagents Preparation and titration of simple organometallic reagents and lithium amide bases Preparation of diazomethane References Gases Introduction Use of gas cylinders Handling gases Measurement of gases Inert gases Reagent gases References Vacuum pumps Introduction House vacuum systems (low vacuum) Medium vacuum pumps High vacuum pumps Pressure measurement and regulation Carrying out the reaction Introduction Reactions with air-sensitive reagents Reaction monitoring Reactions at other than room temperature Driving equilibria Agitation Use of controlled reactor systems References Working up the reaction Introduction Quenching the reaction Isolation of the crude product Data that need to be collected on the crude product prior to purification Purification Introduction Crystallization Distillation Sublimation Flash chromatography Dry-column flash chromatography Preparative TLC Medium pressure and prepacked chromatography systems Preparative HPLC References Small-scale reactions Introduction Reactions at or below room temperature Reactions above room temperature Reactions in NMR tubes Purification of materials Large-scale reactions Introduction Carrying out the reaction Workup and product isolation Purification of the products Special procedures Introduction Catalytic hydrogenation Photolysis Ozonolysis Flash vacuum pyrolysis (FVP) Liquid ammonia reactions Microwave reactions References Characterization Introduction NMR spectra IR spectra UV spectroscopy Mass spectrometry Melting point (m.p.) and boiling point (b.p.) Optical rotation Microanalysis Keeping the data Troubleshooting: What to do when things don't work The chemical literature The structure of the chemical literature Some important paper-based sources of chemical information Some important electronic-based sources of chemical information How to find chemical information Current awareness References Appendices Properties of common solvents Properties of common gases Approximate pKa values for some common reagents versus common bases Common Bronsted acids Common Lewis acids Common reducing reagents Common oxidizing reagents Index.
• (source: Nielsen Book Data)

Any research that uses new organic chemicals, or ones that are not commercially available, will at some time require the synthesis of such compounds. Therefore, organic synthesis is important in many areas of both applied and academic research, from chemistry to biology, biochemistry, and materials science. The third edition of a bestseller, Advanced Practical Organic Chemistry is a guide that explains the basic techniques of organic chemistry, presenting the necessary information for readers to carry out widely used modern organic synthesis reactions. This book is written for advanced undergraduate and graduate students as well as industrial organic chemists, particularly those involved in pharmaceutical, agrochemical, and other areas of fine chemical research. It provides the novice or nonspecialist with the often difficult-to-find information on reagent properties needed to perform general techniques. With over 80 years combined experience training and developing organic research chemists in industry and academia, the authors offer sufficient guidance for researchers to perform reactions under conditions that give the highest chance of success, including the appropriate precautions to take and proper experimental protocols. The text also covers the following topics: * Record keeping and equipment * Solvent purification and reagent preparation * Using gases and working with vacuum pumps * Purification, including crystallization and distillation * Small-scale and large-scale reactions * Characterization, including NMR spectra, melting point and boiling point, and microanalysis * Efficient ways to find information in the chemical literature With fully updated text and all newly drawn figures, the third edition provides a powerful tool for building the knowledge on the most up-to-date techniques commonly used in organic synthesis.
(source: Nielsen Book Data)

• Safety
• keeping records of laboratory work
• equipping the laboratory and the bench
• purification and drying of solvents
• reagents - purification and handling
• gases
• vacuum pumps
• carrying out the reaction
• working up the reaction
• purification
• small-scale reactions
• large-scale reactions
• characterization
• the chemical literature
• special procedures
• trouble shooting.
• (source: Nielsen Book Data)

Any research which uses new organic chemicals or those which are not available commercially will at some time require the synthesis of such compounds. This practical book covers the most up-to-date techniques commonly used in organic synthesis, and updates the first edition. This book should be of interest to: postgraduate industrial and advanced undergraduate organic chemists; biologists, biochemists and genetic engineers; material scientists; polymer researchers; and pharmaceutical, agrochemical and others involved with fine chemicals research and electronics.
(source: Nielsen Book Data)

• Chapter 1. Introduction
• * Nomenclature, Structure, and Stability * Generation of Carbocations * The Non-Classical Ion Controversy * Electrophilic Addition to Alkenes * Electrophilic Aromatic Substitution * Elimination reactions * Rearrangement Reactions of Carbocations * References
• Chapter 2. Nucleophilic Aliphatic Substitution - SN1
• * Introduction *-Activated Alcohols-Bronsted Acids *-Activated Alcohols-Lewis Acids * Alkylation of Aldehydes and Ketones * Glycosylation * Friedel-Crafts Alkylation and Acylation * Electrophilic Fluorination Using Fluoronium Ion * Miscellaneous SN1-related Reactions * References
• Chapter 3. Nucleophilic Aliphatic Substitution - SN2
• * Construction of Quaternary Stereogenic Centers * Sulfur Chemistry * Organometallic Chemistry * Macrocyclization * Glycosylation * Nucleoside Analogues *N-Alkylation * Cyclotetraphosphazenes * Conformationally Locked Tetrahydropyran Ring * The Ionic Liquid Effect * Silver Chemistry * References Chapter 4. Electrophilic Addition to Alkenes
• * Introduction * Cyclopropanation * Hydroboration/Oxidation * The Pauson-Khand Reaction * Prins Reaction * Schmidt Reaction * Halogenation * Oxymercuration/Reduction * Epoxidation * Gold-Catalyzed Alkyne Hydration * Conclusion * References
• Chapter 5. Electrophilic Aromatic Substitution
• * Introduction * Nitration * Halogenation * Friedel-Crafts Alkylation * Friedel-Crafts Acylation * Applications of Friedel-Crafts Reaction on Total Synthesis * Miscellaneous Electrophilic Aromatic Substitution Reactions * References
• Chapter 6. Fragmentation and Rearrangement Reactions
• * Claisen Rearrangements * Cope Rearrangements * Cope Rearrangements * Aldehyde (or Ketone) Formation Rearrangements * Carboxylic Acid Formation Rearrangements * Alcohol Formation Rearrangements * Amine Formation Rearrangement * Amides * Hydrocarbon Rearrangements * Oxacyclic, Carbocyclic, Oxazoles, Tetrahydrapuran and Tetrahydropuran Formation Rearrangements * Rearrangements resulting in less common functional groups * Fragmentations * References.
• (source: Nielsen Book Data)

Carbocation chemistry is not only fundamental to the advancement of organic chemistry, it also has found widespread applications in organic synthesis. It is not an exaggeration to say that carbocation chemistry is part of the foundation of organic chemistry. Carbocation Chemistry: Applications in Organic Synthesis provides a panoramic view of carbocation chemistry with an emphasis on synthetic applications. This book is an invaluable tool for organic, medicinal and analytical chemists, including those working in biochemistry as well as the petroleum, plastics and pharmaceutical industries. It is also suitable for upper level undergraduates and graduates in organic chemistry, biochemistry and medicinal chemistry.
(source: Nielsen Book Data)

Contains a large selection of movies from the best selling visualization software package for chemistry students.

• Introduction Synthesis of Pyrroles and N-Vinylpyrroles by the Reaction of Ketones (Ketoximes) with Acetylenes Heterocyclization of ketoximes with acetylene Regioselectivity of the reaction Substituted acetylenes in reactions with ketoximes Vinyl halogenides and dihalogenethanes as synthetic equivalents of acetylene Intermediate stages and side reactions delta-Carbolines from 3-acylindoles and acetylene Reaction of ketoximes with acetylene in the presence of ketones. One-pot assembly of 4-methylen-3-oxa-1-azabicyclo[3.1.0]hexanes Transformations of aldoximes in the systems MOH/DMSO and MOH/DMSO/acetylene Mechanism of pyrrole synthesis from ketoximes and acetylene Novel Aspects of NH- and N-Vinylpyrroles Reactivity Reaction with the participation of the pyrrole ring Reactions with participation of the vinyl group Conclusions References Index.
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During the last 30 years, knowledge of the essential role that pyrrole structures play in the chemistry of living organisms, drug design, and the development of advanced materials has increased. Correspondingly, research on the diverse issues of synthetic, theoretical, and applied chemistry has snowballed. Devoted to the latest achievements of this field, Chemistry of Pyrroles covers the discovery and development of a novel, facile, and highly effective method for the construction of the pyrrole ring from ketones (ketoximes) and acetylene in superbase catalytic systems (Trofimov reaction). It provides cutting-edge details on the preparation of valuable but previously inaccessible pyrrole compounds. It includes approximately 1,000 structures of novel pyrrole compounds, their yields, and physical-chemical characteristics. The authors analyze conditions of typical syntheses, limitations of their applicability, and possibility of vinyl chloride or dichloroethane application instead of acetylene. They examine chemical engineering aspects of the first synthesis of tetrahydroindole and indole from commercially available oxime of cyclohexanone and acetylene. In addition, the book discusses new facets of pyrroles and N-vinyl pyrroles reactivity in the reactions with the participation of both the pyrrole ring and N-vinyl groups. The book provides condensed, clear-cut information on novel syntheses of substituted pyrroles as key structural units of living matter (chlorophyll and hemoglobin), pharmaceuticals, and monomers for optoelectronic materials. It includes tables that provide references to original works, forming a guide to a variety of the reactions and synthesized compounds discussed. With coverage of the broad range of pyrrole chemistry and methods for their synthesis, it provides both a theoretical and an experimental basis for drug design.
(source: Nielsen Book Data)

• Separation and purification of mixtures
• Modification of sp3 carbon
• Substitution at non-aryl sp2 carbon
• Addition at non-aryl sp2 carbon
• Electrophilic Aromatic Substitution
• Nucleophilic Aromatic Substitution
• Transition Metal Catalysed Substitution
• Addition to sp carbon
• Preparation of alkenes
• Peryciclic reactions
• Radical reactions
• Oxidations
• Reductions
• Rearrangements
• Biotransformations
• Polymerization reactions
• Other transformations
• Chiral Resolutions--.
• (source: Nielsen Book Data)

This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
(source: Nielsen Book Data)

• PREFACE TO THE SECOND EDITION
• .1. INTRODUCTION.1.1 The Structure and Forms of Water.1.2 Properties of Water.1.3 Solvation.1.4 Hydrophobic Effect.1.5 Salt Effect.1.6 Water Under Extreme Conditions.References.
• 2. ALKANES.2.1 Oxygenation of Alkanes.2.2 Halogenation of Alkanes.2.3 Formation of Carbon-Carbon Bonds.2.4 D/H Exchange of Alkanes in Water.References.
• 3. ALKENES.3.1 Reduction.3.2 Electrophilic Additions.3.3 Radical Reactions of Alkenes.3.4 Carbene Reactions.3.5 Alkene Isomerization.3.6 Transition-Metal Catalyzed C-C Formation Reactions.3.7 Olefin Metathesis.3.8 Reaction of Allylic C-H Bond
• .4. ALKYNES.4.1 Reaction of Terminal Alkynes.4.2 Additions of C C bonds.4.3 Transition-Metal Catalyzed Cycloadditions.4.4 Other Reactions.References.
• 5. ALCOHOLS, PHENOLS, ETHERS, THIOLS, AND THIOETHERS.5.1 Oxidation of Alcohols.5.2 Substitutions/Elimination.5.3 Addition of Alcohols, Phenols, and Thiols to Alkene and Alkyne Bonds.5.4 Addition of Alcohols to C=O Bonds: Esterification and Acetal Formations.5.5 Reaction of Ethers and Cyclic Ethers.5.6 Reaction of Sulfur Compounds
• .6. ORGANIC HALIDES.6.1 General.6.2 Reduction.6.3 Elimination Reactions.6.4 Nucleophilic Substitutions.6.5 Reductive Coupling.6.6 Carbonylation of Organic Halides.6.7 Transition-Metal Catalyzed Coupling Reactions.References.
• 7. AROMATIC COMPOUNDS.7.1 General.7.2 Substitution Reactions.7.3 Oxidation Reactions.7.4 Reductions.References.
• 8. ALDEHDYE AND KETONES.8.1 Reduction.8.2 Oxidation.8.3 Nucleophilic Addition: C-C Bond Formation.8.4 Pinacol Coupling.8.5 Other Reactions (Halogenation and Oxidation of alpha-H).References.
• 9. CARBOXYLIC ACIDS AND DERIVATIVES.9.1 General.9.2 Carboxylic Acids.9.3 Carboxylic Acid Derivatives.References.
• 10. CONJUGATED CARBONYL COMPOUNDS.10.1 Reduction.10.2 Epoxidation, Dihydroxylation, Hydroxyamination.10.3 Conjugate Addition: Heteroatom.10.4 C-C Bond Formation.10.5 Other Reactions.References.
• 11. NITROGEN COMPOUNDS.11.1 Amines.11.2 Imines.11.3 Diazo Compounds.11.4 Azides.11.5 Nitro Compounds.References.
• 12. PERICYCLIC REACTIONS.12.1 Introduction.12.2 Diels-Alder Reactions.12.3 Sigmatropic Rearrangements.12.4 Photochemical Cycloaddition Reactions.References. INDEX.
• (source: Nielsen Book Data)

This is an extensive update of the classic reference on organic reactions in water. Published almost a decade ago, the first edition has served as the guide for research in this burgeoning field. Due to the cost, safety, efficiency, and environmental friendliness of water as a solvent, there are many new applications in industry and academic laboratories. More than forty percent of this extensively updated second edition covers new reactions. For ease of reference, it is organized by functional groups.A core reference, "Comprehensive Organic Reactions in Aqueous Media, Second Edition": provides the most comprehensive coverage of aqueous organicreactions available; covers the basic principles and theory and progresses to applications; includes alkanes, alkenes, aromatics, electrophilic substitutions, carbonyls, alpha, beta-unsaturated carbonyls, carbon-nitrogen bonds, organic halides, pericyclic reactions, photochemical reactions, click chemistry, and multi-step syntheses; and, provides examples of applications in industry. This is the premier reference for chemists and chemical engineers in industry or research, as well as for students in advanced-level courses.
(source: Nielsen Book Data)

• Acknowledgements.Preface.
• Chapter 1. Quantum Mechanics for Organic Chemistry .
• Chapter 2. Fundamentals of Organic Chemistry.
• Chapter 3. Pericyclic Reactions.
• Chapter 4. Diradicals and Carbenes.Chapter 5.Organic Reactions of Anions.
• Chapter 6. Solution-Phase Organic Chemistry.
• Chapter 7. Organic Reaction Dynamics.
• (source: Nielsen Book Data)

'[This book] collects together, largely for the first time, a series of chapters dedicated to all the ways in which molecular modeling/computational chemistry can impact organic chemistry' - Christopher J. Cramer, author of "Essentials of Computational Chemistry: Theories and Models". "Computational Organic Chemistry" provides a practical overview of the ways in which computational modeling methods and applications can be used in organic chemistry to predict the structure and reactivity of organic molecules. After a concise survey of computational methods, the book presents in-depth case studies that show how various computational methods have provided critical insight into the nature of organic mechanisms. With a focus on methodologies, this unique resource: discusses simple molecular properties, pericyclic reactions, carbenes and radicals, anion chemistry, solvent effects, and more; features sidebars that offer a personal look at some of the leading practitioners in the field; conveys the strengths and limitations of each method, so that readers develop a feel for the correct 'tool' to use in the context of a specific problem; and, further informs readers with a supporting Web site that provides links to materials cited and features a blog that discusses and provides links to new relevant articles. This is a great reference for practicing physical organic and computational chemists, as well as a thought-provoking textbook for graduate-level courses in computational chemistry and organic chemistry.
(source: Nielsen Book Data)

• Foreword vii Preface ix Copper-Catalyzed Amination of Aryl and Alkenyl Electrophiles 1 Kevin H. Shaughnessy, Engelbert Ciganek, and Rebecca B. DeVasher
• Index 675.
• (source: Nielsen Book Data)

The metal-catalyzed amination of aryl and alkenyl electrophiles has developed into a widely used methodology for the synthesis of natural products, active pharmaceutical ingredients, agricultural chemicals, and materials for molecular electronics. Copper catalysts promote the coupling of a wide range of nitrogen nucleophiles, including amines, amides, and heteroaromatic nitrogen compounds with aryl and alkenyl halides. The reactivity profile of copper catalysts is complementary to that of palladium catalysts in many cases. Copper catalysts are highly effective with less nucleophilic nitrogen nucleophiles, such as amides and azoles, whereas palladium catalysts are more effective with more nucleophilic amine nucleophiles. Copper is an attractive alternative to palladium due to its significantly lower cost. In addition, high activity palladium catalysts require expensive and often air-sensitive ligands, whereas the modern copper systems use relatively stable and inexpensive diamine or amino acid ligands. Copper-catalyzed C N coupling reactions are tolerant of a wide range of functional groups and have been applied to the synthesis of a variety of complex natural products. Significant work has also been done to understand the mechanism of these reactions. Current mechanistic understanding of these methodologies is covered in this monograph. The contents of the book are taken from the comprehensive review of the topic in the Organic Reactions series. Optimal experimental conditions for the amination of aryl and alkenyl halides with all classes of nitrogen nucleophiles are presented. Specific experimental procedures from the literature are provided for the major classes of copper-catalyzed C N coupling reactions. A tabular survey of all examples of Cu-catalyzed arylation and alkenylation of nitrogen nucleophiles is presented in 35 tables organized by nitrogen nucleophile and electrophilic coupling partner. The literature is covered through December 2015 and provides 300 recent citations to supplement the 680 citations of the original hardbound chapter. These latest literature references have been collected in separate sections according to the sequence of the tables in the tabular survey section. In each of the sections, the individual citations have been arranged in alphabetic order of the author names. Copper-Catalyzed Amination of Aryl and Alkenyl Electrophiles is intended to provide organic chemists with an accessible, but detailed, introduction to this important class of transformations.
(source: Nielsen Book Data)

"The CrossFire system is a complete chemical information system comprising the Beilstein Database, the CrossFire search and retrieval server software and the Beilstein Commander client" --p. 8
The Beilstein database contains data from the Beilstein Handbook (1779-1959), primary literature from 1960 to 1979, and primary literature data from 1979. Cf. p. 11.

• Preface
• Chapter 1: Organic Compounds
• Chapter 2: Inorganic and Organometallic Compounds
• Chapter 3: Properties of Atoms, Radicals, and Bonds
• Chapter 4: Physical Properties
• Chapter 5: Thermodynamic Properties
• Chapter 6: Spectroscopy
• Chapter 7: Physiochemical Relationships
• Chapter 8: Electrolytes, Electromotive Force, and Chemical Equilibrium
• Chapter 9: Data Useful in Laboratory Manipulations and Analysis
• Chapter 10: Polymers, Rubbers, Fats, Oils, and Waxes
• Chapter 11: Abbreviations, Constants, and Conversion FactorsINDEX.
• (source: Nielsen Book Data)

Get the organic chemistry answers you need - in a flash! Packed with nearly 50 per cent new content, this revised edition of "Dean's Handbook of Organic Chemistry" delivers comprehensive coverage, with practical information, key equations and tables, and a thorough introduction to each topic. Edited by a renowned expert in organic chemistry, this book updates: biopolymers; electronegativity; nomenclatures for supramolecular compounds; properties tables for atoms, radicals, and bonds; line-angle structural drawings; and much, much more!No matter if you're a chemist, a chemical or environmental engineer, or even a student, "Dean's Handbook of Organic Chemistry" will add precision, insight, and a host of timesaving tips to your efforts. It provides complete coverage of: organic compounds; inorganic compounds; properties of atoms, radicals, and bonds; physical properties; thermodynamic properties; spectroscopy; physicochemical relationships; electrolytes, electromotive force, and chemical equilibrium; laboratory manipulations; and, polymers, rubbers, fats, oils, and waxes.
(source: Nielsen Book Data)

• Data provided in each entry includes (where relevant): molecular formula
• structure diagram
• preferred names and synonyms
• CAS registry numbers
• physical description
• biological source
• stability
• solvent of recrystallisation
• solubility
• melting point
• freezing point
• boiling point
• density
• refractive index
• optical rotation
• use or importance
• hazard and toxicity data
• selective literature references.
• (source: Nielsen Book Data)

This dictionary of organic compounds should be of interest to chemists, biochemists, biologists and pharmacologists working within academic, industrial or governmental organizations.
(source: Nielsen Book Data)

• 1 BONDING AND ELECTRON DISTRIBUTION 1 1.1 The Decision-Based Approach To Organic Chemistry2 1.2 Ionic And Covalent Bonding 6 1.3 Lewis Structures And Resonance Forms 8 1.4 Curved-Arrow Notation 11 1.5 Nomenclature And Abbreviations 16 1.6 An Orbital View Of Bonding (Supplemental) 18 1.7 The Shapes Of Molecules 21 1.8 Molecular Repulsions, Attractions, And Hydrogen Bonding25 1.9 Conjugation, Vinylogy, Aromaticity 27 1.10 Summary 30 2 THE PROCESS OF BOND FORMATION 34 2.1 Energetics Control Knowledge 35 2.2 Orbital Overlap In Covalent Bond Formation 35 2.3 Orbital Interaction Diagrams 38 2.4 Polarizability And Hard And Soft Acid-Base Theory 41 2.5 Thermodynamics, Position Of Equilibrium 43 2.6 Kinetics, Rate Of Reaction 47 2.7 Solvent Stabilization Of Ions 53 2.8 Enzymatic Catalysis - Lessons From Biochemistry 55 2.9 Summary 57 3 PROTON TRANSFER AND THE PRINCIPLES OF STABILITY61 3.1 Introduction To Proton Transfer 62 3.2 Ranking Of Acids And Bases, The pKa Chart 63 3.3 Structural Factors That Influence Acid Strength 66 3.4 Structural Factors That Influence Base Strength 70 3.5 Carbon Acids & Ranking Of Electron-Withdrawing Groups71 3.6 Calculation Of Keq For Proton Transfer 76 3.7 Proton Transfer Mechanisms 77 3.8 Common Errors 81 3.9 Proton Transfer Product Predictions 82 3.10 Summary 83 4 IMPORTANT REACTION ARCHETYPES 88 4.1 Introduction To Reaction Archetypes 89 4.2 Nucleophilic Substitution At A Tetrahedral Center 89 4.3 Elimination Reactions Create Pi Bonds 110 4.4 Addition Reactions To Polarized Multiple Bonds 124 4.5 Nucleophilic Substitution At A Trigonal Planar Center133 4.6 Electrophilic Substitution At A Trigonal Planar Center140 4.7 Rearrangements To An Electrophilic Carbon 144 4.8 Reaction Archetype Summary 146 5 CLASSIFICATION OF ELECTRON SOURCES 151 5.1 Generalized Ranking Of Electron Sources 151 5.2 Nonbonding Electrons 152 5.3 Electron-Rich Sigma Bonds 154 5.4 Electron-Rich Pi Bonds 155 5.5 Simple Pi Bonds 156 5.6 Aromatic Rings 159 5.7 Summary Of Generic Electron Sources 160 6 CLASSIFICATION OF ELECTRON SINKS 166 6.1 Generalized Ranking Of Electron Sinks 166 6.2 Electron-Deficient Species 167 6.3 Weak Single Bonds 168 6.4 Polarized Multiple Bonds Without Leaving Groups 170 6.5 Polarized Multiple Bonds With Leaving Groups 172 6.6 Summary Of Generic Electron Sinks 173 7 THE ELECTRON FLOW PATHWAYS 179 7.1 The Dozen Most Common Pathways 180 7.2 Six Minor Pathways 191 7.3 Common Path Combinations 197 7.4 Variations On A Theme 201 7.5 Twelve Major Paths Summary And Crosschecks 208 8 INTERACTION OF ELECTRON SOURCES AND SINKS 213 8.1 Source And Sink Correlation Matrix 214 8.2 H-A Sinks Reacting With Common Sources 214 8.3 Y-L Sinks Reacting With Common Sources 218 8.4 sp3 C-L Sinks Reacting With Common Sources222 8.5 C=Y Sinks Reacting With Common Sources 227 8.6 R-C Y Sinks Reacting With Common Sources233 8.7 C=C?Ewg Sinks Reacting With Common Sources 235 8.8 L-C=Y Sinks Reacting With Common Sources 237 8.9 Miscellaneous Reactions 240 8.10 Metal Ions As Electron Sinks 242 8.11 Rearrangements To An Electrophilic Center 243 8.12 Nu-L Reactions 244 8.13 Product Matrix Summary 248 9 DECISIONS, DECISIONS 251 9.1 Decision Point Recognition 252 9.2 Multiple Additions 252 9.3 Regiochemistry & Stereochemistry Of Enolate Formation254 9.4 Ambident Nucleophiles 255 9.5 Substitution Vs. Elimination 258 9.6 Ambident Electrophiles 262 9.7 Intermolecular Vs. Intramolecular 263 9.8 To Migrate Or Not To An Electrophilic Center 264 9.8 Summary 266 10 CHOOSING THE MOST PROBABLE PATH 269 10.1 Problem-Solving In General 270 10.2 General Mechanistic Cross-Checks 274 10.3 The Path-Selection Process 276 10.4 Reaction Mechanism Strategies 278 10.5 Worked Mechanism Examples 279 10.6 Product Prediction Strategies 297 10.7 Worked Product Prediction Examples 297 10.8 Methods For Testing Mechanisms 313 10.9 Lessons from Biochemical Mechanisms 319 10.10 Summary 321 11 ONE-ELECTRON PROCESSES 326 11.1 Radical Structure And Stability 326 11.2 Radical Path Initiation 329 11.3 Major Paths For Radicals Reacting With Neutrals330 11.4 Unimolecular Radical Paths 332 11.5 Termination Radical Paths 333 11.6 Radical Path Combinations 333 11.7 Approaches To Radical Mechanisms 336 11.8 Single Electron Transfer, S.E.T., And ChargedRadicals 338 11.9 Dissolving Metal Reductions 339 11.10 Electron Transfer Initiated Processes 340 11.11 One-Electron Path Summary 340 12 QUALITATIVE M.O. THEORY & PERICYCLIC REACTIONS 343 12.1 Review Of Orbitals As Standing Waves 344 12.2 Molecular Orbital Theory For Linear Pi Systems344 12.3 Molecular Orbital Theory For Cyclic Conjugated PISystems 348 12.4 Perturbation Of The HOMO And LUMO 351 12.5 Delocalization Of Sigma Electrons (Supplemental)352 12.6 Concerted Pericyclic Cycloaddition Reactions 353 12.7 Concerted Pericyclic Electrocyclic Reactions 357 12.8 Concerted Pericyclic Sigmatropic Rearrangements359 12.9 Pericyclic Reactions Summary 361 APPENDIX (A COLLECTION OF IMPORTANT TOOLS) 364 General Bibliography 364 Abbreviations Used in This Text 365 Functional Group Glossary 366 Composite pKa Chart 369 Bond Strength Table 372 Generic Classification Guide 373 Flow Charts for the Classification of Electron Sources and Sinks375 Pathway Summary 375 Trends Guide 380 Major Routes Summary 384 Major Decisions Guide 388 Thermodynamics and Kinetics 390 Generation of Alternate Paths, Reaction Cubes 390 Organic Structure Elucidation Strategies 393 Notes on Nomenclature 399 HINTS TO PROBLEMS FROM CHAPTERS 8, 9, AND 10 404 INDEX 407.
• (source: Nielsen Book Data)

Using a mechanistic approach, the text explains and makes use of analysis tools rare in undergraduate organic chemistry texts (flow charts as decision maps, correlation matrices to show all possible interactions, and simplified energy surfaces used as problem space maps), helping readers develop a good intuition for organic chemistry and the ability to approach and solve complex problems methods of analysis that are valuable and portable to other fields. This revised Second Edition builds on and improves the legacy of the first edition's unique decision-based approach to teaching/learning organic chemistry.
(source: Nielsen Book Data)

• Introduction
• Examples of pre-laboratory and post-laboratory exercises
• The place of pre-laboratory exercises
• Pressures on laboratory work
• Coping strategies
• Facilitating learning
• Pre-laboratory exercises
• Laboratory effectiveness and pre-laboratory exercises
• The aims of laboratory work
• Pre-laboratory exercises in use today
• What might be included in pre-laboratory exercises?
• Post-laboratory exercises
• Writing pre-laboratory and post-laboratory exercises
• Epilogue.
• (source: Nielsen Book Data)

Laboratory work is an essential part of undergraduate chemistry courses. The laboratory provides a setting for training not just in practical hand and instrument skills, but also for other skills such as planning, recording, interpreting and working in teams. However, students often learn little from their time in the laboratory and find it hard to make connections with lectures. Over half of third-level chemical students have no intention of becoming practising chemists anyway. Teaching staff may also feel pressured in relation to manpower, materials, time and safety. Carrying out exercises before and after laboratory sessions can maximise the benefit of practical work for higher education students. This books surveys existing materials for pre-laboratory and post-laboratory exercises in the chemical sciences. Twenty examples are given, and guidance is provided for constructing similar exercises.
(source: Nielsen Book Data)

• Introduction Transition Metal-Catalyzed Asymmetric Epoxidations Manganese Systems Iron and Ruthenium Systems Titanium Systems Systems Based on Other Metals Transition Metal-Catalyzed Asymmetric Sulfoxidations Vanadium Systems Titanium Systems Iron Systems Systems Based on Other Metals Miscellaneous Transition Metal-Catalyzed Asymmetric Oxidations Cis-Dihydroxylations of Olefins Baeyer-Villiger Oxidations Oxidative Kinetic Resolution of Secondary Alcohols and Desymmetrization of Meso-Diols Enantioselective Aerobic Oxidative Coupling of 2-Naphthols Enantioselective C-H Oxidations Organocatalytic Asymmetric Oxidations Epoxidations Miscellaneous Oxidations Fe- and Mn-Based Synthetic Models of Non-Heme Oygenases: Stereospecific C-H Oxidations Iron Systems Manganese Systems Active Species and Mechanisms of Non-Heme Fe- and Mn-Catalyzed Oxidations Iron Systems Manganese Systems Industrial Perspective General Remarks Some Examples Outlook.
• (source: Nielsen Book Data)

Catalysis plays a vital role in chemical, petroleum, agriculture, polymer, electronics, pharmaceutical, and other industries. Over 90 percent of chemicals originate from catalytic processes. Toughening economic and environmental constraints have proven to be a challenge for meeting the demand of novel efficient and sustainable regio- and stereoselective catalyst systems. Environmentally Sustainable Catalytic Asymmetric Oxidations provides a comprehensive overview of existing ecologically friendly catalyst systems for various asymmetric oxidation processes. Topics include: * A survey of existing transition metal-based catalyst systems for asymmetric epoxidations (AEs) with O2 and H2O2 * Asymmetric sulfoxidations with H2O2 on chiral metal complexes * An overview of various transition metal-catalyzed oxidative transformations with H2O2 or O2 used as the terminal oxidant * Organocatalytic asymmetric oxidations * Catalytic processes of stereospecific oxidations of C-H functional groups * The role that oxoiron(V) intermediates play in chemo- and stereoselective oxidations catalyzed by non-heme iron complexes The book concludes with a discussion of the opportunities and problems associated with the industrial application of stereoselective processes of catalytic oxidation with H2O2 and O2. It also provides examples of processes with industrial potential. Some of the catalysts presented in this book may serve as promising alternatives for existing catalysts-progressively replacing them in manufacturing processes and ultimately making the chemical industry greener and cleaner.
(source: Nielsen Book Data)

• Preface
• Part 1: Laboratory Practice Safety in the Chemical Laboratory Glasware and Equipment in the Laboratory Organic Reactions: from Starting Materials to Pure Organic Product Qualitative Analysis of Organic Compounds Spectroscopic Analysis of Organic Compounds Keeping Records: the Laboratory Notebook and Chemical Literature
• Part 2: Experimental Procedures Introduction List of Experiments Experiments which can be Taken in Sequence Experiments which Illustrate Particular Techniques Functional Group Interconversions Carbon - Carbon Bond-Forming Reactions Appendice Index of Chemicals General Index.
• (source: Nielsen Book Data)

• Preface
• Part 1: Laboratory Practice1 Safety in the Chemical Laboratory2 Glasware and Equipment in the Laboratory3 Organic Reactions: from Starting Materials to Pure Organic Product4 Qualitative Analysis of Organic Compounds5 Spectroscopic Analysis of Organic Compounds6 Keeping Records: the Laboratory Notebook and Chemical Literature
• Part 2: Experimental ProceduresIntroductionList of ExperimentsExperiments which can be Taken in SequenceExperiments which Illustrate Particular Techniques7 Functional Group Interconversions8 Carbon - Carbon Bond-Forming Reactions 9 ProjectsAppendicesIndex of ChemicalsGeneral Index.
• (source: Nielsen Book Data)

This established text continues to provide a rigorous account of the principles and practice of experimental organic chemistry, taking students from their first day in the laboratory right through to research work. New to this edition, a microscale approach has been integrated into the entire text, alongside conventional manipulations, bringing it in line with current laboratory practice. Maintaining the unique structure of the previous edition, the first half of the book surveys all aspects of safe laboratory practice, the use of a wide range of purification and analytical techniques, particularly spectroscopic analysis. The second half contains easy-to-follow experimental procedures, each designed to illustrate an important reaction type of basic principle of organic chemistry. Tried and tested over the past decade, these experiments are graded according to their complexity and many of these have microscale equivalents. Of prime importance, all aspects of health and safety in the laboratory have been updated according to the latest guidelines and are highlighted throughout the text.
(source: Nielsen Book Data)

An autobiography by the chemist best known for total steroid synthesis and biogenetic-like cyclizations.
(source: Nielsen Book Data)

• Molecules, mechanisms, acids and bases
• reactions with nucleophiles
• reactions with electrophiles
• reactions with radiacal intermediates
• taking it further.
• (source: Nielsen Book Data)

• 1. Molecules
• 2. Mechanisms
• 3. Acids and bases
• 4. Reactions with nucleophiles
• 5. Reactions with electrophiles
• 6. Reactions with radical intermediates
• 7. Taking it further
• Index.
• (source: Nielsen Book Data)

Aimed at advanced sixth form and beginning undergraduate students, this book presents the foundations of organic chemistry. The first chapters introduce some basic physical chemistry and lay the groundwork for the mechanistic organic chemistry covered later in the book. The importance of bonding and mechanism is stressed throughout, and students are encouraged to apply their chemical knowledge in new and unfamiliar situations in order to develop and sustain their interest. A range of examples including natural products and parmaceuticals is included, with the last chapter exploring some new developments and providing an introduction to current research.
(source: Nielsen Book Data)
Advanced school students and beginning undergraduates will find this book a readable and stimulating summary of the fundamentals of organic chemistry. The first three chapters introduce some basic physical chemistry, and lay the groundwork for the mechanistic organic chemistry covered later in this book. The importance of bonding and mechanism are stressed throughout, and students are encouraged to apply their chemical knowledge in new and unfamiliar situations in order to develop and sustain their interest. A wide range of examples including natural products and pharmaceuticals is included, with the final chapter exploring some new developments and providing an introduction to current research.
(source: Nielsen Book Data)

• Prologue and Introduction to Part I Background. Chapter 1. An Introduction to Structure and Bonding. A. The Sources of Carbon Compounds. B. More About Hydrocarbons. C. On the Nature of the Chemical Bond. Chapter 2. An Introduction to Spectroscopy and Selected Spectroscopic Methods in Organic Chemistry. A. General Introduction. B. X-Ray Crystallography. C. Photon Spectroscopy. D. Mass Spectrometry. Chapter 3. Structure: The Nomenclature of Hydrocarbons and the Shape of Things to Come. A. Introduction. B. Nomenclature and Spectroscopy. C. Physical and Chemical Properties
• Oxidation and Reduction of Hydrocarbons. Chapter 4. An Introduction to Dynamics. A. Introduction. B. Review of Some Energy Considerations. C. The Barrier Between Reactants and Products. D. More About the Transition State. E. Rotation About Sigma (s) Bonds in Acyclic Alkanes, Alkenes, Alkynes and Alkyl Substituted Arenes. F. Conformational Analysis of Medium-Ring Cyclic Alkanes . G. The Conservation of Symmetry During Reactions. H. The Measurement of Chirality. Chapter 5. Classes of Organic Compounds - A Survey. An Introduction to Solvents, Acids and Bases
• Computational Chemistry. A. Introduction. B. General Characteristics of Functional Group Placement. C. The Functional Groups and Their Names. D. An Introduction to Solvents. E. Acids and Bases. F. Computational Methods. Introduction to Part II Middleground. Chapter 6. Reactions of Hydrocarbons: Oxidation, Reduciton, Substitution, Addition, Elimination and Rearrangement. A. Introduction. B. Alkanes. C. Alkenes. D. Alkynes. E. Arenes and Aromaticity: Special Introduction. Chapter 7. The Reactions of Alkl, Alkenyl and Aryl Halides: Oxidation Reduction, Substitution, Addition Elimination, and Rearrangement. A. Introduction. B. Fluorocarbons. C. Oxidation. D. Reduction of Alkyl, Aldenyl and Aryl Halides. E. Nucleophilic Substitution. F. Addition Reactions. G. Elimination Reactions of Alkyl and Alkenyl Halides. H. Rearrangement Reactions of Alkyl and Alkenyl Halides. Chapter 8. Part I The Reactions of Alcohols, Enols and Phenols: Oxidation Reduction, Substitution, Addition Elimination, and Rearrangement. Part II Ethers. Part III Selected Reactions Of Alkyl and Aryl Thiols and Thioethers. Special Introduction. Part I. Alcohols, Enols and Phenols. A. Acidity and Basicity. B. Oxidation of Alcohols, Enols and Phenols. C. Reduction of Alcohols, Enols and Phenols. D. Substitution Reactions of Alcohols, Enols and Phenols. E. Addition Reactions of Alcohols, Enols and Phenols. G. Rearrangement Reactions of Alcohols, Enols and Phenols. Part II. Ethers. I. Introduction II. The Reactions of Ethers. Part III. Thiols, Thioethers, and Some Products of Their Oxidation. Chapter 9. Part I The Reactions of Aldehydes and Ketones: Oxidation, Reduction, Substitution, Addition Elimination, and Rearrangement. Part II The Reactions of Carboxylic Acids and Their Derivatives: Oxidation, Reduction, Substitution, Addition Elimination, and Rearrangement. Introduction. Part I. Aldehydes and Ketones. A. Oxidation of Aldehydes and Ketones. B. Reduction of Aldehydes and Ketetones. C. Addition to Aldehydes and Ketones. D. Substitution Reactions Producing Aldehydes and Ketones. E. Rearrangement Reactions of Aldehydes and Ketones. Part II. Carboxylic Acids and Their Derivatives. A. General Introduction. B. Oxidation. C. Reduction. D. Substitution: Addition and Elimination. E. Additional Reactions and Rearrangements of Esters and ss-Dicarbonyl Compounds. Chapter 10. Part I The Reactions of Amines: Oxidation.Reduction, Addition, Substitution and Rearrangement. Part II Some Organo- phosphorus Chemistry. Part III Some Organosilicon Chemistry. Part I. The Reactions of Amines: Introduction. A. Oxidation of Amines. B. Reduction of Amines. C. Addition and Substitution Reactions of Amines with a General Introduction. D. Addition and Rearrangement Reactions of Amines. Part II: Some Organophosphorus Chemistry. Part III. Some Organosilicon Chemistry. Introduction to Part III Foreground. Chapter 11 An Introduction to Carbohydrates, Acetogenins and Steroids. I. Introduction. II. The Calvin Cycle. III.Carbohydrates. A. Biosynthesis. B. Chemistry. C. Oligosaccharides. D. Polysaccharides. IV. Actetogenins. A. Acetyl Coenzyme A. B. Acetyl CoA to Fatty-Acids and Related Compounds. C. Isoprenoides: To Dimethylallyl Diphosphate and Beyond. Chapter 12 An Introduction to Amino Acids, Peptides and Proteins, Enzymes, Coenzymes and Metabolic Processes. I Introduction. II Amino Acids. A. Biosynthesis. B. Synthesis. III Peptides and Proteins. A. Amino Acids from Peptides. B. Peptides from Amino Acids - in vivo. C. Peptides from Amino Acids - in vitro. IV. The Coenzymes. A. Pyridoxal Phosphate. B. Lipoic Acid. C. Thiamin Diphosphate. D. Biotin. E. Adenosine. F. Nicotinamide Adenine Dinucleotide (NAD + ). G. Coenzyme A (CoA-SH). H. Flavin Adenine Dinucleotide (FAD). I. S-Adenosylmethionine. J. Tetrahydrofolate. Chapter 13 An Introduction to Alkaloids and Some Other Heterocyclic Compounds. I. Introduction. II. Tropane Alkaloids. A. Chemistry of Hyoscyamine. B. Chemistry of Nicotine. C. Biosynthesis of Hyoscyamine and Nicotine. III. Morphine (and Codeine and Thebaine). A. Chemistry of Morphine (and Codeine and Thebaine). B. The Biosynthesis of Morphine (and Codeine and Thebaine). C. The Synthesis of Morphine. IV. Vinblastine. A. Chemistry of Vinblastine. B. Biosynthesis of Vinblastine. V. Caffeine. A. Some History and the Synthesis of Caffeine. B. Biosynthesis of Caffeine. Chapter 14 Part I. On the Genetic Code: Unity and Diversity. Part II The Tetrapyrrolic Cofactors: Unity and Diversity. Part I. Introduction (The Genetic Code ). Part A The Bases of Deoxyribonucleic Acid (DNA and Ribonucleic Acid (RNA). A. Deoxynucleotides. B. The Role of Phosphate Part B. A. The Sequencing of DNA. B. Chemical Synthesis of DNA. C. Modification to DNA. Part II The Tetrapyrrolic Cofactors. A. Introduction. B. Some Early Chemistry. C. Current Biosynthetic Understanding. Epilogue. Appendix I The Schrodinger Equation. Appendix II The Literature.
• (source: Nielsen Book Data)

This book differs from other organic chemistry textbooks in that it is not focused purely on the needs of students studying premed, but rather for all students studying organic chemistry. It directs the reader to question present assumptions rather than to accept what is told, sothe second chapter is largely devoted to spectroscopy (rather than finding it much later on as with most current organic chemistry textbooks). Additionally, after an introduction to spectroscopy, thermodynamics and kinetics, the presentation of structural information of compounds and organic families advances from hydrocarbons to alcohols to aldehydes and ketones and, finally, to carboxylic acids.
(source: Nielsen Book Data)

• 1. Structure and Bonding
• Acids and Bases. 2. The Nature of Organic Compounds: Alkanes. 3. The Nature of Organic Reactions: Alkenes. 4. Reactions of Alkenes and Alkynes. 5. Aromatic Compounds. 6. Stereochemistry. 7. Alkyl Halides. 8. Alcohols, Phenols, and Ethers. 9. Aldehydes and Ketones: Nucleophilic Addition Reactions. 10. Carboxylic Acids and Derivatives. 11. Carbonyl Alpha-Substitution Reactions and Condensation Reactions. 12. Amines. INTERLUDE: THE ROADMAP OF CHEMICAL REACTIONS. 13. Structure Determination. 14. Biomolecules: Carbohydrates. 15. Biomolecules: Amino Acids, Peptides, and Proteins. 16. Biomolecules: Lipids and Nucleic Acids. 17. The Organic Chemistry of Metabolic Pathways.
• (source: Nielsen Book Data)

Master organic chemistry with this thorough, to-the-point introduction to the fascinating science of organic chemistry. In every chapter of FUNDAMENTALS OF ORGANIC CHEMISTRY, 7e, you'll find applications that demonstrate how organic chemistry relates to your everyday life, a striking full color art program that helps you visualize chemical processes and reactions, and superior learning tools you can use to study for tests, master key concepts, and succeed in the course.
(source: Nielsen Book Data)
Retaining the concise, to-the-point presentation that has already helped thousands of students move beyond memorization to a true understanding of the beauty and logic of organic chemistry, this Seventh Edition of John McMurry's FUNDAMENTALS OF ORGANIC CHEMISTRY brings in new, focused content that shows students how organic chemistry applies to their everyday lives. In addition, redrawn chemical structures and artwork help students visualize important chemical concepts, a greater emphasis on biologically-related chemistry (including new problems) helps them grasp the enormous importance of organic chemistry in understanding the reactions that occur in living organisms, and new End ofChapter problems keyed to OWL allow them to work text-specific problems online. Lastly, for this edition, John McMurry reevaluated and revised his writing at the sentence level to ensure that the book's explanations, applications, and examples are more student-friendly, relevant, and motivating than ever before.
(source: Nielsen Book Data)

• Brief Table of Contents. Graphical Abstracts for the Experiments.
• 1. INTRODUCTION.
• 2. IDENTIFICATION AND EVALUATION OF CHEMICAL HAZARDS.
• 3. CHEMICAL EXPOSURE AND ENVIRONMENTAL CONTAMINATION.
• 4. SOURCES OF INFORMATION ABOUT CHEMICAL HAZARDS.
• 5. INTRODUCTION TO GREEN CHEMISTRY.
• 6. ALTERNATIVE SOLVENTS.
• 7. ALTERNATIVE REAGENTS.
• 8. REACTION DESIGN AND EFFICIENCY.
• 9. ALTERNATIVE FEEDSTOCKS AND PRODUCTS.
• 10. THE BIG PICTURE AND GREEN CHEMISTRY METRICS. Laboratory Experiments.
• 11. PREFACE TO THE EXPERIMENTAL SECTION. Experiment
• 1: Solventless Reactions: The Aldol Reaction. Experiment
• 2: Bromination of An Alkene: Preparation of Stilbene Dibromide. Experiment
• 3: A Greener Bromination of Stilbene. Experiment
• 4: Preparation and Distillation of Cyclohexene. Experiment
• 5: Synthesis and Recrystallization of Adipic Acid. Experiment
• 6: Oxidative Coupling of Alkynes: The Glaser-Eglinton-Hay Coupling. Experiment
• 7: Gas-Phase Synthesis, Column Chromatography and Visible Spectroscopy of 5,10,15,20-Tetraphenylporphyrin. Experiment
• 8: Microwave Synthesis of 5,10,15,20-Tetraphenylporphyrin. Experiment
• 9: Metallation of 5,10,15,20-Tetraphenylporphyrin. Experiment
• 10: Measuring Solvent Effects: Kinetics of Hydrolysis of tert-Butyl Chloride. Experiment
• 11: Molecular Mechanics Modeling. Experiment
• 12: Electrophilic Aromatic Iodination. Experiment
• 13: Palladium-Catalyzed Alkyne Coupling/Intramolecular Alkyne Addition: Natural Product Synthesis. Experiment
• 14: Resin-Based Oxidation Chemistry. Experiment
• 15: Carbonyl Chemistry: Thiamine-Mediated Benzoin Condensation of Furfural. Experiment
• 16: Solid-Phase Photochemistry. Experiment
• 17: Applications of Organic Chemistry: Patterning Surfaces With Molecular Films. Experiment
• 18: The Friedel-Crafts Reaction: Acetylation of Ferrocene. Experiment
• 19: Combinatorial Chemistry: Antibiotic Drug Discovery. Appendix A: The Twelve Principles of Green Chemistry.
• (source: Nielsen Book Data)

Developing the green organic program at the University of Oregon, Kenneth Doxsee and James Hutchison saw the urgent need and rapidly growing demand for green chemistry laboratory materials. This lab text describes the tools and strategies of green chemistry, and the lab experiments that allow investigation of organic chemistry concepts and techniques in a greener laboratory setting. GREEN ORGANIC CHEMISTRY: STRATEGIES, TOOLS AND LABORATORY EXPERIMENTS was developed and successfully tested as a direct replacement of the traditional organic chemistry laboratory curriculum. Thus, the conceptual themes and experimental techniques important to the modern practice of organic chemistry can be taught in the context of more environmentally-benign laboratory experiments. Students acquire the tools to assess the health and environmental impacts of chemical processes and the strategies to improve develop new processes that are less harmful to human health and the environment. The curriculum introduces a number of state-of-the-art experiments and reduces reliance on expensive environmental controls, such as fume hoods.
(source: Nielsen Book Data)

The features of this book which will be of special interest to academic organic chemists are the introduction (Chapter 1), which presents a short course on the concepts and language of heterogeneous catalysis, covers organic reaction mechanisms of hydrogenation (Chapter 2), hydrogenolysis (Chapter 4), and oxidation (Chapter 6). It presents problems and solutions specific for running heterogeneous catalytic organic reactions in solution. These materials can supplement advanced chemistry courses. Most synthetic organic chemists use a variety of 'protecting groups' which they attach to functional groups (reactive groups of atoms) while some reaction is being conducted on another part of the molecule. These protecting groups prevent reactions of the functional groups during other reactions and are removed later by a heterogeneous catalytic method called hydrogenolysis. One unique feature of this book, not found in other books on catalysis, is an exhaustive chapter (Chapter 4) on hydrogenolysis, which is dredged from the recent synthetic literature published by modern organic chemists. Academic organic chemists should find this chapter extremely useful and may wish to adopt the book as a supplement for advanced organic chemistry courses designed for seniors and for graduate students. It will also be useful for professors and their research groups engaged in synthetic organic chemistry. Many academic organic chemists are not aware of recent advances in heterogeneous enantioselective catalysis (Chapter 3) or in selective low temperature, liquid phase heterogeneous catalytic oxidations by hydrogen peroxide (Chapter 6). These specialty topics are timely and may be new to academic organic chemists and can be used to supplement their advanced courses. Several features of this book will also be of special interest to industrial chemists who are unfamiliar with heterogeneous catalysis. Many good organic chemists are hire by industry. They synthesize a new compound using standard organic synthetic techniques but are informed by their supervisor that they must convert some of their synthetic steps into heterogeneous catalytic steps. They may not have been exposed to heterogeneous catalysis and have few places to turn. This book offers them a crash course in heterogeneous catalysis as well as many examples of reactions and conditions with which they can start their search. Those industrial organic chemists already familiar with heterogeneous catalysis will find this book useful as a reference to many examples in the recent literature. They will find recent surface science discoveries correlated with heterogeneous catalysis or organic reactions and mechanistic suggestions designed to stimulate innovative nontraditional thinking about organic reactions on surfaces. Key features include: written by organic chemists for organic chemists; introduces heterogeneous catalysis concepts and language; presents a comprehensive compilation of protecting group removal procedures; covers liquid-phase hydrogenations, hydrogenolysis, and oxidations; addresses heterogeneous methods for producing pure enantiomers of chiral products; examines the emerging field of heterogenized homogeneous catalysts; and, mixes practical applications with mechanistic interpretations.
(source: Nielsen Book Data)

Designed to supplement existing organic textbooks, Hybrid Retrosynthesis presents a relatively simple approach to solving synthesis problems, using a small library of basic reactions along with the computer searching capabilities of Reaxys and SciFinder. This clear, concise guide reviews the essential skills needed for organic synthesis and retrosynthesis, expanding reader knowledge of the foundational principles of these techniques, whilst supporting their use via practical methodologies. Perfect for both graduate and post-graduate students, Hybrid Retrosynthesis provides new applied skills and tools to help during their organic synthesis courses and future careers, whilst simultaneously acting as useful resource for those setting tutorial and group problems, and as a helpful go-to guide for organic chemists involved in either industry or academia. * Ideal revision and hands on learning guide for organic synthesis * Clearly explains the principles and practice of retrosynthesis, which is often not covered in other books * Encourages readers to practice their synthetic knowledge supported by real life examples.
(source: Nielsen Book Data)

• Ether/or
• The architect of molecules
• Building an unseen structure
• A barometer of the science
• The heuristics of molecular representation
• Molecules as metaphors
• Aromatic apparitions
• Dimensional molecules
• Kopp's world
• Kekulé's "dreams"
• The scientific image-ination.

Chemists in the nineteenth century were faced with a particular problem: how to depict the atoms and molecules beyond the direct reach of our bodily senses. In visualizing this microworld, these scientists were the first to move beyond high-level philosophical speculations regarding the unseen. In "Image and Reality", Alan J. Rocke focuses on the community of organic chemists in Germany to provide the basis for a fuller understanding of the nature of scientific creativity. Arguing that visual mental images assisted many of these scientists in thinking through old problems and new possibilities, Rocke uses a variety of sources, including private correspondence, diagrams and illustrations, scientific papers, and public statements to investigate their ability to not only imagine the invisibly tiny atoms and molecules upon which they operated daily, but to build detailed and empirically based pictures of them. These portrayals of 'chemical structures' gradually became an accepted part of science and are now regarded as one of the defining features of chemistry. In telling this fascinating story, Rocke also suggests that imagistic thinking is often at the heart of creative thinking in all fields.
(source: Nielsen Book Data)

• Preface to the Third Edition xi Preface to the Second Edition xiii Preface to the First Edition xv
• 1 Reading Nomenclature 1 1.1 Acyclic Polyfunctional Molecules 2 1.2 Monocyclic Aliphatic Compounds 3 1.3 Bridged Polycyclic Structures 4 1.4 Fused Polycyclic Compounds 6 1.5 Spiro Compounds 10 1.6 Monocyclic Heterocyclic Compounds 12 1.7 Fused ]Ring Heterocyclic Compounds 14 1.8 Bridged and Spiro Heterocyclic Compounds 19 Resources 20 Problems 21 References 22
• 2 Accessing Chemical Information 25 2.1 Databases 25 2.2 Chemical Literature 26 2.3 Synthetic Procedures 29 2.4 Health and Safety Information 30 Problems 32 References 33
• 3 Stereochemistry 35 3.1 Representations 35 3.2 Vocabulary 37 3.3 Property Differences Among Stereoisomers 40 3.4 Resolution of Enantiomers 44 3.5 Enantioselective Synthesis 47 3.6 Reactions at a Stereogenic Atom 49 3.6.1 Racemization 49 3.6.2 Epimerization 50 3.6.3 Inversion 51 3.6.4 Retention 51 3.6.5 Transfer 52 3.7 Relative and Absolute Configuration 53 3.8 Topism 56 Resources 59 Problems 60 References 65
• 4 Mechanisms and Predictions 69 4.1 Reaction Coordinate Diagrams and Mechanisms 69 4.2 The Hammond Postulate 71 4.3 Methods for Determining Mechanisms 72 4.3.1 Identification of Products and Intermediates 72 4.3.2 Isotope Tracing 73 4.3.3 Stereochemical Determination 74 4.3.4 Concentration Dependence of Kinetics 75 4.3.5 Isotope Effects in Kinetics 85 4.3.6 Temperature Effects on Kinetics 87 4.3.7 Substituent Effects on Kinetics 90 4.4 Representative Mechanisms 95 4.4.1 Reactions in Basic Solution 96 4.4.2 Reactions in Acidic Solution 100 4.4.3 Free ]Radical Reactions 103 4.4.4 Molecular Rearrangements 106 Resources 108 Problems 109 References 120
• 5 Electron Delocalization, Aromatic Character, and Pericyclic Reactions 123 5.1 Molecular Orbitals 124 5.2 Aromatic Character 130 5.3 Pericyclic Reactions 135 5.3.1 Cycloaddition Reactions 137 5.3.2 Electrocyclic Reactions 142 5.3.3 Sigmatropic Reactions 147 Resources 152 Problems 152 References 158
• 6 Functional Group Transformations 163 6.1 Carboxylic Acids and Related Derivatives 164 6.1.1 Carboxylic Acids 164 6.1.2 Carboxylic Esters 166 6.1.3 Carboxylic Amides 168 6.1.4 Carboxylic Acid Halides 168 6.1.5 Carboxylic Anhydrides 169 6.1.6 Nitriles 169 6.1.7 O rtho Esters 170 6.2 Aldehydes, Ketones, and Derivatives 171 6.2.1 Aldehydes 171 6.2.2 Ketones 174 6.2.3 Imines and Enamines 175 6.2.4 Acetals 175 6.2.5 Vinyl Ethers 177 6.3 Alcohols 179 6.4 Ethers 179 6.5 Alkyl Halides 181 6.5.1 Alkyl Chlorides and Alkyl Bromides 182 6.5.2 Alkyl Iodides 184 6.5.3 Alkyl Fluorides 184 6.6 Amines 185 6.7 Isocyanates 187 6.8 Alkenes 187 6.9 Reductive Removal of Functionality 190 Resources 191 Problems 191 References 198
• 7 Carbon Carbon Bond Formation 205 7.1 Carbon Carbon Single Bond Formation 206 7.1.1 Reactions in Basic Solution 206 7.1.2 Reactions in Acidic Solution 214 7.1.3 O rganometallic Coupling Reactions 217 7.2 Carbon Carbon Double ]Bond Formation 218 7.3 Multibond Processes 222 Resources 224 Problems 224 References 230
• 8 Planning Multistep Syntheses 235 8.1 Retrosynthetic Analysis 235 8.2 Disconnection at a Functional Group or Branch Point 236 8.3 Cooperation for Difunctionality 244 8.4 Ring Closure 250 8.5 Acetylide Alkylation and Addition 253 8.6 T he Diels Alder Reaction 255 8.7 T he Claisen Rearrangement 259 8.8 Synthetic Strategies 263 8.9 Final Note 265 Resources 266 Problems 266 References 271
• 9 Physical Influences on Reactions 277 9.1 Unimolecular Reactions 278 9.2 Homogenous Two ]Component Reactions 279 9.3 Temperature Effects 280 9.4 Pressure Effects 281 9.5 Solvent Effects 282 9.6 Biphasic Reactions 283 9.6.1 Phase Transfer Catalysis 283 9.6.2 Increasing Solubility 286 9.6.3 Increasing Surface Area 287 9.6.4 Ultrasound 287 9.7 Reactions on Chemical Supports 288 9.8 Using Unfavorable Equilibria 291 9.9 Green Chemistry 293 Resources 294 Problems 294 References 295
• 10 Survey of Organic Spectroscopy 299 10.1 Electromagnetic Radiation 299 10.2 Ultraviolet Spectroscopy 300 10.2.1 Origin of the Signals 300 10.2.2 Interpretation 302 10.2.3 Visible Spectroscopy 302 10.3 Infrared Spectroscopy 303 10.3.1 Origin of the Signals 304 10.3.2 Interpretation 304 10.4 Mass Spectrometry 305 10.4.1 Origin of the Signals 306 10.4.2 Interpretation 307 10.5 N MR Spectroscopy 309 10.5.1 Origin of the Signals 309 10.5.2 Interpretation of Proton NMR Spectra 311 10.6 Carbon NMR Spectra 323 10.6.1 General Characteristics 323 10.6.2 Interpretation of 13C NMR Spectra 325 10.7 Correlation of 1H and 13C NMR Spectra 327 Resources 329 Problems 329 References 333 Appendix A 337 Appendix B 341 Index 347.
• (source: Nielsen Book Data)

This book presents key aspects of organic synthesis stereochemistry, functional group transformations, bond formation, synthesis planning, mechanisms, and spectroscopy and a guide to literature searching in a reader-friendly manner. Helps students understand the skills and basics they need to move from introductory to graduate organic chemistry classes Balances synthetic and physical organic chemistry in a way accessible to students Features extensive end-of-chapter problems Updates include new examples and discussion of online resources now common for literature searches Adds sections on protecting groups and green chemistry along with a rewritten chapter surveying organic spectroscopy.
(source: Nielsen Book Data)

• Reading Nomenclature. Searching the Literature. Stereochemistry. Functional Group Transformations. Carbon-Carbon Bond Formation. Planning Multistep Syntheses. Mechanisms and Predictions. Electron Delocalization, Aromatic Character, and Pericyclic Reactions. Physical Influences on Reactions. Interpretation of NMR Spectra. Index.
• (source: Nielsen Book Data)

Intermediate Organic Chemistry Second Edition Like its celebrated predecessor, Intermediate Organic Chemistry, Second Edition furnishes students with the information and conceptual skills they will need to make the transition from introductory to graduate-level organic chemistry and to fully comprehend published research. Revised and updated, this new edition features additional and improved examples, explanations which are more detailed and elaborated, and twice as many exercise problems - most based on actual studies in current articles - at the end of each chapter. Problems are presented in raw-data form to encourage multistep thinking and require students to solve problems from the beginning rather than from half-finished setups. The chapter on stereochemistry has been updated to include new terminology; and the chapter on nuclear magnetic resonance has been reframed in terms of pulsed high-field spectrometers. Other subjects covered include: reading nomenclature; searching the literature; functional group transformations; carbon-carbon bond formation; planning multistep syntheses; mechanisms and predictions; electron delocalization, aromatic character, and pericyclic reactions; and physical influences on reactions. An ideal text for one-semester, upper-level undergraduate or first-year graduate courses, Intermediate Organic Chemistry, Second Edition eliminates the problem of selecting or omitting subjects from advanced texts. The book will also be useful to practicing chemists who wish to update their understanding of particular topics.
(source: Nielsen Book Data)

• Strategies for interpreting spectra of organic molecules
• infrared spectroscopy
• nuclear magnetic resonance spectroscopy
• 13C nuclear magnetic resonance spectroscopy
• mass spectroscopy.
• (source: Nielsen Book Data)

This textbook provides an introduction to the types of spectroscopy commonly used to determine the structure of organic molecules. Strategies for interpreting spectra are emphasized and the reader is encouraged to develop a systematic approach to elucidating molecular structure from the types of spectroscopic data routinely obtained in the laboratory. The first chapter discusses the type of information which spectroscopic methods can provide and the way in which this information can be used to determine organic structures. Infrared spectroscopy, mass spectroscopy and nuclear magnetic resonance are dealt with in detail in subsequent chapters. Much information has been summarized in graphical form or has been tabulated for ease of use.
(source: Nielsen Book Data)

• Vibrational and Rotational Spectra. IR Experimental Considerations. Molecular Symmetry. The Vibrational Origin of Group Frequencies. Methyl and Methylene Groups. Triple Bonds and Cumulated Double Bonds. Olefin Groups. Aromatic and Heteroaromatic Rings. Carbonyl Compounds. Ethers, Alcohols, and Phenols. Amines, C=N, and N=O Compounds. Compounds Conking Boron, Silicon, Phosphorus, Sulfur, or Halogen. Major Spectra-Structure Correlations by Spectral Regions. The Theoretical Analysis of Molecular Vibrations.
• (source: Nielsen Book Data)

Now in its third edition, this classic text covers many aspects of infrared and Raman spectroscopy that are critical to the chemist doing structural or compositional analysis. This work includes practical and theoretical approaches to spectral interpretation as well as a discussion of experimental techniques. Emphasis is given to group frequencies, which are studied in detailed discussions, extensive tables, and over 600 carefully chosen and interpreted spectral examples. Also featured is a unique treatment of group frequencies that stresses their mechanical origin. This qualitative approach to vibrational analysis helps to simplify spectral interpretation. Additional topics include basic instrumental components and sampling techniques, quantitative analysis, Raman polarization data, infrared gas contours, and polarized IR studies, among others. Among its key features, it: focuses on group frequency correlations and how to use them in spectral interpretation; is revised and updated by a pioneer in the field, Norman Colthup, who for thirty years has served as an expert lecturer for the Fisk Infrared Institute; explores new group frequency studies in aromatics, alkanes and olefins, among others; and includes completely updated section on instrumentation.
(source: Nielsen Book Data)

• Welcome to organic chemistry
• laboratory safety
• advance preparation and laboratory records
• basic laboratory concepts
• introduction to microscale methods
• introduction to molecular modelling
• preparations and reactions of organic compounds
• identification of organic substance
• macroscale experiments
• project-based experiments
• the techniques.
• (source: Nielsen Book Data)

This introduction to organic laboratory techniques includes essays on experiments, and emphasizes the development of the important laboratory techniques, the use of spectroscopy and instrumental methods of analysis. A section featuring conventional-scale experiments and methods is included.
(source: Nielsen Book Data)

• Part I: INTRODUCTION TO BASIC LABORATORY TECHNIQUES. Experiment 1. Solubility. Experiment 2. Crystallization. Experiment 3. Extraction. Experiment 4. Chromatography. Experiment 5. Simple and Fractional Distillation. Experiment 6. Infrared Spectroscopy and Boiling-Point Determination. Essay: Aspirin. Experiment 7. Acetylsalicylic Acid. Essay: Analgesics. Experiment 8. Acetanilide. Experiment 9. Acetaminophen. Essay: Identification of Drugs. Experiment 10. TLC Analysis of Analgesic Drugs. Essay: Caffeine. Experiment 11. Isolation of Caffeine. Experiment 11A. Isolation of Caffeine from Tea Leaves. Experiment 11B. Isolation of Caffeine from a Tea Bag. Essay: Esters
• Flavors and Fragrances. Experiment 12. Isopentyl Acetate (Banana Oil). Experiment 13. Methyl Salicylate (Oil of Wintergreen). Essay: Terpenes and Phenylpropanoids. Experiment 14. Isolation of Eugenol from Cloves. Essay: Stereochemical Theory of Odor. Experiment 15. Spearmint and Caraway Oil: (+)- and (-)- Carvones. Essay: The Chemistry of Vision. Experiment 16. Isolation of Chlorophyll and Carotenoid Pigments from Spinach. Essay: Ethanol and Fermentation Chemistry. Experiment 17. Ethanol from Sucrose. Part II: INTRODUCTION TO MOLECULAR MODELING. Essay: Molecular Modeling and Molecular Mechanics. Experiment 18. An Introduction to Molecular Modeling. Experiment 18A. The Conformations of n-Butane: Local Minima. Experiment 18B. Cyclohexane Chair and Boat Conformations. Experiment 18C. Substituted Cyclohexane Rings. Experiment 18D. cis- and trans-2-Butene. Essay: Computational Chemistry
• Ab initio and Semiempirical Methods. Experiment 19. Computational Chemistry. Experiment 19A. Heats of Formation: Isomerism, Tautomerism, and Regioselectivity. Experiment 19B. Heats of Reactions: SN1 Reaction Rates. Experiment 19C. Density-Electrostatic Potential. Maps
• Acidities of Carboxylic Acids. Experiment 19D. Density
• Electrostatic Potential Maps: Carbocations. Experiment 19E. Density
• LUMO Maps: Reactivities of Carbonyl Groups. Part III: PROPERTIES AND REACTIONS OF ORGANIC COMPOUNDS. Experiment 20. Reactivities of Some Alkyl Halides. Experiment 21. Nucleophilic Substitution Reactions: Competing Nucleophiles. Experiment 21A. Competing Nucleophiles with 1-Butanol or 2-Butanol. Experiment 21B. Competing Nucleophiles with 2-Methyl-2-Propanol. Experiment 21C. Analysis. Experiment 22. Hydrolysis of Some Alkyl Chlorides Experiment 23. Synthesis of n-Butyl Bromide and t-Pentyl Chloride. Experiment 23A. n-Butyl Bromide. Experiment 23B. t-Pentyl Chloride. Experiment 24. 4-Methylcyclohexene Experiment 25. Phase-Transfer Catalysis: Addition of Dichlorocarbene to Cyclohexene Essay: Fats and Oils. Experiment 26. Methyl Stearate from Methyl Oleate. Essay: Soaps and Detergents. Experiment 27. Preparation of Soap. Experiment 28. Preparation of a Detergent. Essay: Petroleum and Fossil Fuels. Experiment 29. Gas Chromatographic Analysis of Gasolines. Essay: Detection of Alcohol: The Breathalyzer. Experiment 30. Chromic Acid Oxidation of Alcohols Experiment 30A. Chromic Acid Oxidation of Alcohols
• Visible Spectrophotometer Method. Experiment 30B. Chromic Acid Oxidation of Alcohols
• UV-VIS Spectrophotometer Method. Essay: Green Chemistry. Experiment 31. Chiral Reduction of Ethyl Acetoacetate-- Optical Purity Determination. Experiment 31A. Chiral Reduction of Ethyl Acetoacetate. Experiment 31B. NMR Determination of the Optical Purity of (S)-Ethyl 3-Hydroxybutanoate. Experiment 32. Nitration of Aromatic Compounds Using a Recyclable Catalyst. Experiment 33. An Oxidation-Reduction Scheme: Borneol, Camphor, Isoborneol. Experiment 34. Multi-Step Reaction Sequences: The Conversion of Benzaldehyde to Benzilic Acid. Experiment 34A. Preparation of Benzoin by Thiamine Catalysis Experiment 34B. Preparation of Benzil. Experiment 34C. Preparation of Benzilic Acid. Experiment 35. Tetraphenylcyclopentadienone. Experiment 36. Triphenylmethanol and Benzoic Acid. Experiment 36A. Triphenylmethanol. Experiment 36B. Benzoic Acid. Experiment 37. Resolution of (+/-)-alpha-Phenylethylamine and Determination of Optical Purity. Experiment 37A. Resolution of (+/-)-alpha-Phenylethylamine. Experiment 37B. Determination of Optical Purity Using NMR and a Chiral Resolving Agent. Experiment 38. The Aldol Condensation Reaction: Preparation of Benzalacetophenones Chalcones). Experiment 39. Preparation of an alpha, beta-Unsaturated Ketone via Michael and Aldol Condensation Reactions. Experiment 40. Enamine Reactions: 2-Acetylcyclohexanone. Experiment 41. 1,4-Diphenyl-1,3-Butadiene. Experiment 42. Relative Reactivities of Several Aromatic Compounds. Experiment 43. Nitration of Methyl Benzoate. Essay: Local Anesthetics. Experiment 44. Benzocaine. Essay: Pheromones: Insect Attractants and Repellents. Experiment 45. N, N-Diethyl-m-Toluamide: The Insect Repellent "OFF". Essay: Sulfa Drugs. Experiment 46. Sulfa Drugs: Preparation of Sulfanilamide. Essay: Food Colors. Experiment 47. Chromatography of Some Dye Mixtures. Essay: Polymers and Plastics. Experiment 48. Preparation and Properties of Polymers: Polyester, Nylon, and Polystyrene. Experiment 48A. Polyesters. Experiment 48B. Polyamide (Nylon). Experiment 48C. Polystyrene. Experiment 48D. Infrared Spectra of Polymer Samples. Essay: Diels-Alder Reactions and Insecticides. Experiment 49. The Diels-Alder Reaction of Cyclopentadiene with Maleic Anhydride. Experiment 50. Photoreduction of Benzophenone and Rearrangement of Benzpinacol to Benzopinacolone. Experiment 50A. Photoreduction of Benzophenone. Experiment 50B. Synthesis of beta-Benzopinacolone: The Acid-Catalyzed Rearrangement of Benzpinacol. Essay: Fireflies and Photochemistry. Experiment 51. Luminol. Essay: The Chemistry of Sweeteners. Experiment 52. Carbohydrates. Experiment 53. Analysis of a Diet Soft Drink by HPLC. Essay: Chemistry of Milk. Experiment 54. Isolation of Casein and Lactose from Milk. Experiment 54A. Isolation of Casein from Milk. Experiment 54B. Isolation of Lactose from Milk. Part IV: IDENTIFICATION OF ORGANIC SUBSTANCES. Experiment 55. Identification of Unknowns. Experiment 55A. Solubility Tests. Experiment 55B. Tests for the Elements (N, S, X). Experiment 55C. Tests for Unsaturation. Experiment 55D. Aldehydes and Ketones. Experiment 55E. Carboxylic Acids. Experiment 55F. Phenols. Experiment 55G. Amines. Experiment 55H. Alcohols. Experiment 55I. Esters. Part V: PROJECT-BASED EXPERIMENTS. Experiment 56. Preparation of a C-4 or C-5 Acetate Ester. Experiment 57. A Separation and Purification Scheme. Experiment 57A. Extractions with a separatory funnel. Experiment 57B. Extractions with a Screw-Cap centrifuge tube. Experiment 58. Isolation of Essential Oils from Allspice, Cloves, Cumin, Caraway, Cinnamon, or Fennel. Experiment 58A. Isolation of Essential Oils by Steam Distillation. Experiment 58B. Identification of the Constituents of Essential Oils by Gas Chromatography-Mass Spectrometry. Experiment 58C. Investigation of the Essential Oils of Herbs and Spices-Mini-Research Project. Experiment 59. Friedel-Crafts Acylation. Experiment 60. The Analysis of Antihistamine Drugs by Gas Chromatography-Mass Spectrometry. Experiment 61. Carbonation of an Unknown Aromatic Halide. Experiment 62. The Aldehyde Enigma. Experiment 63. Synthesis of Substituted Chalcones: A Guided-Inquiry Experience. Experiment 64. Michael and Aldol Condensation Reactions. Experiment 65. Esterification Reactions of Vanillin: The Use of NMR to Solve a Structure Proof Problem. Experiment 66. An Oxidation Puzzle. Part VI: THE TECHNIQUES. Technique 1. Laboratory Safety. Technique 2. The Laboratory Notebook, Calculations, and Laboratory Records. Technique 3. Laboratory Glassware: Care and Cleaning. Technique 4. How to Find Data for Compounds: Handbooks and Catalogues. Technique 5. Measurement of Volume and Weight. Technique 6. Heating and Cooling Methods. Technique 7. Reaction Methods. Technique 8. Filtration. Technique 9. Physical Constants of Solids: The Melting Point. Technique 10. Solubility. Technique 11. Crystallization: Purification of Solids. Technique 12. Extractions, Separations, and Drying Agents. Technique 13. Physical Constants of Liquids: The Boiling Point and Density. Technique 14. Simple Distillation. Technique 15. Fractional Distillation, Azeotropes. Technique 16. Vacuum Distillation, Manometers. Technique 17. Sublimation. Technique 18. Steam Distillation. Technique 19. Column Chromatography. Technique 20. Thin-Layer Chromatography. Technique 21. High-Performance Liquid Chromatography (HPLC). Technique 22. Gas Chromatography. Technique 23. Polarimetry. Technique 24. Refractometry. Technique 25. Infrared Spectroscopy. Technique 26. Nuclear Magnetic Resonance Spectroscopy (Proton NMR). Technique 27. Carbon-13 Nuclear Magnetic Resonance Spectroscopy. Technique 28. Mass Spectrometry. Technique 29. Guide to the Chemical Literature. Appendix 1: Tables of Unknowns and Derivatives. Appendix 2: Procedure for Preparing Derivatives. Appendix 3: Index of Spectra.
• (source: Nielsen Book Data)

In this laboratory textbook for students of organic chemistry, experiments are designed to utilize standard-scale ("macroscale") glassware and equipment but with smaller amounts of chemicals and reagents. The textbook features a large number of traditional organic reactions and syntheses, as well as the isolation of natural products and experiments with a biological or health science focus. The organization of the text is based on essays and topics of current interest. There are six introductory technique-based experiments and eleven project-based experiments. In addition, there is a section of green chemistry experiments. The book contains a comprehensive treatment of laboratory techniques, including small-scale and some microscale methods.
(source: Nielsen Book Data)

• Introduction Reductions Oxidations of C, H- and C=C Bonds Oxidative Allylic Oxygenation and Amination Oxidation of Heteroatoms Cross Coupling Reactions Aromatic Substitutions Nucleophilic Substitutions Addition to Carbonyl Compounds Cyclisations Ring Opening Reactions Iron-Catalysis in Biological Environment.
• (source: Nielsen Book Data)

There is a strong need for smaller, more focused and accessible organic chemistry textbooks to guide students through the key principles of the subject, as a result of the modularisation of chemistry courses, which has lead to a less integrated approach to teaching and frequent examination of students. Under these circumstances, the traditional organic chemistry textbook, which tends to be very large, is starting to overpower the average student. This book aims to provide concise organic chemistry notes for students studying chemistry and related courses at undergraduate level. The material is organised such that fundamental concepts are introduced early, and then built on to provide an overview of the key principles of functional group chemistry and reactivity, which is the core of a solid understanding of organic chemistry. Graphical presentation of information is central to the book, to facilitate the rapid assimilation and understanding of key concepts, principles and definitions. First year students wanting an overview of the key principles and fundamental concepts which govern the whole of organic chemistry, and final year students preparing for examinations, should find the book an ideal source of information.
(source: Nielsen Book Data)

• PART I: INTRODUCTION TO THE ORGANIC LABORATORY
• Essay: Introduction to the Organic Laboratory 1. Safety in the Laboratory 2. Protecting the Environment 3. Laboratory Notebooks and Prelaboratory Information PART II: CARRYING OUT CHEMICAL REACTIONS
• Essay: Carrying Out Chemical Reactions 4. Laboratory Glassware 5. Measurements and Transferring Reagents 6. Heating and Cooling Methods 7. Carrying out Organic Reactions 8. Computational Chemistry PART III: BASIC METHODS FOR SEPARATION, PURIFICATION, AND ANALYSIS
• Essay: Intermolecular Forces in Organic Chemistry 9. Filtration 10. Extraction 11. Drying Organic Liquids and Recovering Reaction Products 12. Boiling Points and Distillation 13. Refractometry 14. Melting Points and Melting Ranges 15. Recrystallization 16. Sublimation 17. Optical Activity and Enantiomeric Analysis PART IV: CHROMATOGRAPHY
• Essay: Modern Chromatographic Separations 18. Thin-Layer Chromatography 19. Liquid Chromatography 20. Gas Chromatography
• PART V: SPECTROMETRIC CHARACTERIZATION METHODS
• Essay: The Spectrometric Revolution 21. Infrared Spectroscopy 22. Nuclear Magnetic Resonance Spectroscopy 23. 13C and Two-Dimensional NMR Spectroscopy 24. Mass Spectrometry 25. Ultraviolet and Visible Spectroscopy 26 . Integrated Spectrometry Problems PART VI: DESIGNING AND CARRYING OUT ORGANIC EXPERIMENTS 27. Using the Literature of Organic Chemistry 28. Designing a Chemical Reaction.
• (source: Nielsen Book Data)

"Laboratory Techniques in Organic Chemistry" is the most comprehensive and detailed presentation of the lab techniques organic chemistry students need to know. Compatible with any organic chemistry lab manual or set of experiments, it combines specific instructions for three different kinds of laboratory glassware: miniscale, standard taper microscale, and Williamson microscale. It is written to provide effective support for guided-inquiry and design-based experiments and projects, as well as for traditional lab experiments.
(source: Nielsen Book Data)

The iconic chemistry handbook-extensively updated and thoroughly up to date The standard reference for chemists for more than 70 years, this resource contains vast amounts of facts, data, tabular material, and experimental findings in every area of chemistry. Included in this fully updated compendium are listings of the properties of more than 4,000 organic and 1,400 inorganic compounds. Lange's Handbook of Chemistry, 17th Edition, is divided into six sections-general information and conversion tables, spectroscopy, inorganic chemistry, organic chemistry, petroleum and petroleum products, biomass and biofuels, and environmental science. Existing tables have been thoroughly overhauled and new tables have been added that cover the properties of coal, minerals, natural gas, oil shale, and petroleum. * Features equations that allow you to calculate important values such as temperature and pressure * Contains newly expanded sections on timely topics, including the properties of petroleum products, the environmental properties of chemicals, and proper clean-up methods * Includes updated viscosity, thermal conductivity, critical constants, explosion limits, and vapor density data.
(source: Nielsen Book Data)

• The alkanes
• the alkenes
• the alkynes
• the arenes
• halo-alkanes
• Grignard and alkyllithium reagents
• hydroxyl compounds
• ethers
• epoxides
• thiols and thioethers
• the carbonyl group
• unsaturated carbonyl compounds
• amines
• carbohydrates
• carboxylic acids
• carboxylic esters
• amides
• acyl halides
• acid anhydrides
• cyanides (nitriles)
• bifunctional acids and esters
• amino acids peptides
• carbonic acids and their derivatives
• sulphoxides and sulphones
• sulphonic acids and their derivatives
• nitro compounds
• carbon-nitroso compounds
• heterocyclic compounds
• basic organic photochemistry
• appendices - some approximate chemical shift ranges for different groups, NMR data for some common deuterated solvents, some typical values for I.R. vibrational frequencies.
• (source: Nielsen Book Data)

This text is designed to provide first-year students with a concise guide to the important general reactions of organic chemistry, which form the foundation of all later work. The book should enable students to understand organic reactions and the inter-relationship between organic compounds.
(source: Nielsen Book Data)

• About the writing of this book
• Before college
• Higher education and the army
• University of California, Berkeley
• Carbon acidity
• Theoretical chemistry
• f-Orbital organometallic chemistry
• Heterocycle polycations
• Odds and ends.
• (source: Nielsen Book Data)

This lively autobiography begins with the neighborhood lots of New York where the author began experimenting with organic synthesis, resulting in his first publication while he was still living with his parents. Streitwieser traces his remarkable career from his early research in "wet" chemistry at Berkeley through his work on ab initio theoretical calculations and his "invention" of an entirely new series of compounds, the uranocenes, and analogs to the ferrocenes.
(source: Nielsen Book Data)

• PREFACE xiii COMMON ABBREVIATIONS xxi BIOGRAPHICAL STATEMENT xxv PART I INTRODUCTION 1
• 1. Localized Chemical Bonding 3 1.A. Covalent Bonding 3 1.B. Multiple Valence 6 1.C. Hybridization 7 1.D. Multiple Bonds 9 1.E. Photoelectron Spectroscopy 11 1.F. Electronic Structures of Molecules 14 1.G. Electronegativity 15 1.H. Dipole Moment 18 1.I. Inductive and Field Effects 19 1.J. Bond Distances 21 1.K. Bond Angles 25 1.L. Bond Energies 27
• 2. Delocalized Chemical Bonding 31 2.A. Molecular Orbitals 32 2.B. Bond Energies and Distances in Compounds Containing Delocalized Bonds 35 2.C. Molecules that have Delocalized Bonds 37 2.D. Cross-Conjugation 42 2.E. The Rules of Resonance 43 2.F. The Resonance Effect 45 2.G. Steric Inhibition of Resonance and the Influences of Strain 46 2.H. pp-dp Bonding. Ylids 49 2.I. Aromaticity 50 2.J. Alternant and Nonalternant Hydrocarbons 63 2.K. Aromatic Systems with Electron Numbers other than Six 65 2.L. Other Aromatic Compounds 82 2.M. Hyperconjugation 85 2.N. Tautomerism 89
• 3. Bonding Weaker Than Covalent 96 3.A. Hydrogen Bonding 96 3.B. p-p Interactions 103 3.C. Addition Compounds 104 3.D. Catenanes and Rotaxanes 118 3.E. Cucurbit[n]Uril-Based Gyroscane 121
• 4. Stereochemistry and Conformation 122 4.A. Optical Activity and Chirality 122 4.B. What Kinds of Molecules Display Optical Activity? 125 4.C. The Fischer Projection 136 4.D. Absolute Configuration 137 4.E. The Cause of Optical Activity 145 4.F. Molecules with more than One Stereogenic Center 146 4.G. Asymmetric Synthesis 149 4.H. Methods of Resolution 154 4.I. Optical Purity 160 4.J. cis trans Isomerism 162 4.K. Out-In Isomerism 168 4.L. Enantiotopic and Diastereotopic Atoms, Groups, and Faces 170 4.M. Stereospecific and Stereoselective Syntheses 173 4.N. Conformational Analysis 173 4.O. Molecular Mechanics 190 4.P. STRAIN 192
• 5. Carbocations, Carbanions, Free Radicals, Carbenes, and Nitrenes 208 5.A. Carbocations 208 5.B. Carbanions 221 5.C. Free Radicals 234 5.D. Carbenes 249 5.E. Nitrenes 257
• 6. Mechanisms and Methods of Determining them 261 6.A. Types of Mechanism 261 6.B. Types of Reaction 262 6.C. Thermodynamic Requirements for Reaction 264 6.D. Kinetic Requirements for Reaction 266 6.E. The Baldwin Rules for Ring Closure 270 6.F. Kinetic and Thermodynamic Control 271 6.G. The Hammond Postulate 272 6.H. Microscopic Reversibility 273 6.I. Marcus Theory 273 6.J. Methods of Determining Mechanisms 275
• 7. Irradiation Processes in Organic Chemistry 289 7.A. Photochemistry 289 7.B. Sonochemistry 307 7.C. Microwave Chemistry 309
• 8. Acids and Bases 312 8.A. Bronsted Theory 312 8.B. The Mechanism of Proton-Transfer Reactions 323 8.C. Measurements of Solvent Acidity 324 8.D. Acid and Base Catalysis 327 8.E. Lewis Acids and Bases 330 8.F. The Effects of Structure on the Strengths of Acids and Bases 334 8.G. The Effects of the Medium on Acid and Base Strength 343
• 9. Effects of Structure and Medium on Reactivity 347 9.A. Resonance and Field Effects 347 9.B. Steric Effects 349 9.C. Quantitative Treatments of the Effect of Structure on Reactivity 352 9.D. Effect of Medium on Reactivity and Rate 361 PART II INTRODUCTION 367
• 10. Aliphatic Substitution, Nucleophilic and Organometallic 373 10.A. Mechanisms 373 10.B. SET Mechanisms 389 10.C. The Neighboring-Group Mechanism 391 10.D. The SNi Mechanism 408 10.E. Nucleophilic Substitution at an Allylic Carbon: Allylic Rearrangements 409 10.F. Nucleophilic Substitution at an Aliphatic Trigonal Carbon: The Tetrahedral Mechanism 413 10.G. Reactivity 417 10.H. Reactions 451
• 11. Aromatic Substitution, Electrophilic 569 11.A. Mechanisms 569 11.B. Orientation and Reactivity 576 11.C. Quantitative Treatments of Reactivity in the Substrate 586 11.D.A Quantitative Treatment of Reactivity of the Electrophile: The Selectivity Relationship 588 11.E. The Effect of the Leaving Group 591 11.F. Reactions 591
• 12. Aliphatic, Alkenyl, and Alkynyl Substitution, Electrophilic and Organometallic 649 12.A. Mechanisms 650 12.B. Reactivity 658 12.C. Reactions 660
• 13. Aromatic Substitution: Nucleophilic and Organometallic 732 13.A. Mechanisms 732 13.B. Reactivity 741 13.C. Reactions 745
• 14. Substitution Reactions: Radical 803 14.A. Mechanisms 803 14.B. Reactivity 812 14.C. Reactions 821
• 15. Addition to Carbon-Carbon Multiple Bonds 859 15.A. Mechanisms 859 15.B. Orientation and Reactivity 871 15.C. Reactions 881
• 16. Addition to Carbon-Hetero Multiple Bonds 1067 16.A. Mechanism and Reactivity 1067 16.B. Reactions 1075
• 17. Eliminations 1253 17.A. Mechanisms and Orientation 1253 17.B. Regiochemistry of the Double Bond 1269 17.C. Stereochemistry of the Double Bond 1273 17.D. Reactivity 1274 17.E. Mechanisms and Orientation in Pyrolytic Eliminations 1278 17.F. Reactions 1282
• 18. Rearrangements 1321 18.A. Mechanisms 1322 18.B. Longer Nucleophilic Rearrangements 1331 18.C. Free Radical Rearrangements 1333 18.D. Carbene Rearrangements 1337 18.E. Electrophilic Rearrangements 1337 18.F. Reactions 1337
• 19. Oxidations and Reductions 1433 19.A. Mechanisms 1434 19.B. Reactions 1436 APPENDIX A: THE LITERATURE OF ORGANIC CHEMISTRY 1569 APPENDIX B: CLASSIFICATION OF REACTIONS BY TYPE OF COMPOUNDS SYNTHESIZED 1605 INDEXES AUTHOR INDEX 1631 SUBJECT INDEX 1835.
• (source: Nielsen Book Data)

The new, revised and updated 7th edition of March's Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7th edition: * Every chapter has been updated with the most recent reaction information with references to both the primary and review literature * New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B * Contains more than 1650 reactions and 20,000 valuable references to the primary literature * Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized * Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. Reviews of the previous edition: "...a favorite general organic chemistry text and an easy-to-use one-volume reference. We are confident that this book will remain a dominant reference and that it will reside on many chemists' personal bookshelves." --Journal of Medicinal Chemistry "Who can hope to be seriously accepted as a member of the organic chemistry community without being in possession of at least one edition of 'March'?" --Chemistry and Industry.
(source: Nielsen Book Data)

• Preface.Biographical Note.Abbreviations.PART 1.
• Chapter 1. Localized Chemical Bonding.
• Chapter 2. Delocalized Chemical Bonding.
• Chapter 3. Bonding Weaker than Covalent.
• Chapter 4. Stereochemistry.
• Chapter 5. Carbocations, Carbanions, Free Radicals, Carbenes, and Nitrenes.
• Chapter 6. Mechanisms and Methods of Determining Them.
• Chapter 7. Irradiation Processes in Organic Chemistry.
• Chapter 8. Acids and Bases.
• Chapter 9. Effects of Structure on Reactivity.PART 2
• Chapter 10. Aliphatic Substitution: Nucleophilic and Organometallic.
• Chapter 11. Aromatic Substituion, Electrophilic.
• Chapter 12. Aliphatic, Alkenyl, and Alkynyl Substitution, Electrophilic and Organometallic.
• Chapter 13. Aromatic Substitution, Nucleophilic and Organometallic.
• Chapter 14. Substitution Reactions: Free Radicals.
• Chapter 15. Addition to Carbon-Carbon Multiple Bonds.
• Chapter 16. Addition to Carbon-Hetero Multiple Bonds.
• Chapter 17. Eliminations.
• Chapter 18. Rearrangements.
• Chapter 19. Oxidations and Reductions.Appendix A. The Literature of Organic Chemistry.Appendix B. Classification of Reactions by Type of Compound SynthesizedIndexes.Author Index.Subject Index.
• (source: Nielsen Book Data)

The Sixth Edition of a classic in organic chemistry continues its tradition of excellence. Now in its sixth edition, "March's Advanced Organic Chemistry" remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: more than 25,000 references to the literature to facilitate further research; revised mechanisms, where required, that explain concepts in clear modern terms; revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries; and, a revised Appendix B to facilitate correlating chapter sections with synthetic transformations.
(source: Nielsen Book Data)

• Bibliographical Note. Abbreviations.
• PART 1. Localized Chemical Bonding. Delocalized Chemical Bonding. Bonding Weaker than Covalent. Stereochemistry. Carbocations, Carbanions, Free Radicals, Carbenes, and Nitrenes. Mechanisms and Methods of Determining Them. Photochemistry. Acids and Bases. Effects of Structure on Reactivity.
• PART 2. Aliphatic Nucleophilic Substitution. Aromatic Electrophilic Substitution. Aliphatic Electrophilic Substitution. Aromatic Nucleophilic Substitution. Free-Radical Substitution. Addition to Carbon-Carbon Multipe Bonds. Addition to Carbon-Hetero Multipe Bonds. Eliminations. Rearrangements. Oxidations and Reductions. Appendix A: The Literature of Organic Chemistry. Appendix B: Classification of Reactions by Type of Compound Synthesized. Author Index. Subject Index.
• (source: Nielsen Book Data)

From the reviews of the Fourth Edition ..."March has been uncompromising in his search for clarity and utility in presentations of a wide variety of essential organic chemistry. It remains an accessible and useful tool for both specialists and nonspecialists in the field. It does an excellent job both as a text for first-year graduate students and a handy reference for others."-Journal of Chemical Education "The ratio of information to price makes this book a wonderful bargain."-American Scientist New to this Fifth Edition: Michael Smith from the University of Connecticut joins as coauthor for the Fifth Edition Contains 20,000 valuable, selected references to the primary literature-5,000 new to this edition 40 entirely new sections covering the most important developments in organic chemistry since the previous edition Updated illustrations of molecular structures.
(source: Nielsen Book Data)

This work helps students identify basic reaction types in organic chemistry and methods for determining mechanisms, including product studies, kinetics and the identification of intermediates.
(source: Nielsen Book Data)

• Preface. Introduction. I. MASTERING THE OPERATIONS.
• 1. Learning Basic Operations. The Effect of pH on a Food Preservative.
• 2. Extraction and Evaporation. Separating the Components of "Panacetin."
• 3. Recrystallization and Melting-Point Measurement. Identifying a Constituent of "Panacetin."
• 4. Heating under Reflux. Synthesis of Salicylic Acid from Wintergreen Oil.
• 5. Simple Distillation, Gas Chromatography. Preparation of Synthetic Banana Oil.
• 6. Fractional Distillation. Separation of Petroleum Hydrocarbons.
• 7. Addition, Mixing, Sublimation. Preparation of Camphor.
• 8. Boiling Point, Refractive Index. Identification of a Petroleum Hydrocarbon.
• 9. Column Chromatography, UV-VIS Spectrometry. Isolation and Isomerization of Lycopene from Tomato Paste.
• 10. Steam Distillation, Infrared Spectrometry. Isolation and Identification of the Major Constituent of Clove Oil.
• 11. Thin-Layer Chromatography, NMR Spectrometry. Identification of Unknown Ketones.
• 12. Vacuum Distillation, Optical Rotation. Optical Activity of a-Pinene. II. CORRELATED LABORATORY EXPERIMENTS.
• 13. Investigation of a Chemical Bond by Infrared Spectrometry.
• 14. Properties of Common Functional Groups.
• 15. Thin-Layer Chromatographic Analysis of Drug Components.
• 16. Separation of an Alkane Clathrate.
• 17. Isomers and Isomerization Reactions.
• 18. Structures and Properties of Stereoisomers.
• 19. Bridgehead Reactivity in an SN1 Solvolysis Reaction.
• 20. Reaction of Iodoethane with Saccharin, an Ambident Nucleophile.
• 21. Dehydration of Methylcyclohexanols.
• 22. Synthesis of 7,7-Dichloronorcarane Using a Phase-Transfer Catalyst.
• 23. Stereochemistry of the Addition of Bromine to trans-Cinnamic Acid.
• 24. Hydration of a Difunctional Alkyne.
• 25. Preparation of Bromotriphenylmethane and the Trityl Free Radical.
• 26. Chain-Growth Polymerization of Styrene and Methyl Methacrylate.
• 27. Synthesis of Ethanol by Fermentation.
• 28. Reaction of Butanols with Hydrobromic Acid.
• 29. Borohydride Reduction of Vanillin to Vanillyl Alcohol.
• 30. Synthesis of Triphenylmethanol and the Trityl Carbocation.
• 31. Identification of a Conjugated Diene from Eucalyptus Oil.
• 32. Spectral Identification of Monoterpenoids.
• 33. Synthesis and Spectral Analysis of Aspirin.
• 34. Preparation of Nonbenzenoid Aromatic Compounds.
• 35. Mechanism of the Nitration of Arenes by Nitronium Fluoborate.
• 36. Friedel-Crafts Acylation of Anisole.
• 37. Structure of a Natural Product in Anise Oil.
• 38. Identification of an Oxygen-Containing Organic Compound.
• 39. Wittig Synthesis of 1,4-Diphenyl-1,3-Butadiene.
• 40. Effect of Reaction Conditions on the Condensation of Furfural with Cyclopentanone.
• 41. Haloform Oxidation of 4'-Methoxyacetophenone.
• 42. Electronic Effect of a para-Iodo Substituent.
• 43. Synthesis and Identification of an Unknown Carboxylic Acid.
• 44. Preparation of the Insect Repellent N, N-Diethyl-meta-toluamide.
• 45. Synthesis of 2-Acetylcyclohexanone by the Stork Reaction.
• 46. Synthesis of Dimedone and Measurement of its Tautomeric Equilibrium Constant.
• 47. Preparation of Para Red and Related Azo Dyes.
• 48. Reaction of Phthalimide with Sodium Hypochlorite.
• 49. Identification of an Unknown Amine.
• 50. Preparation and Mass Spectrum of 2-Phenylindole.
• 51. Nucleophilic Strength and Reactivity in SNAr Reactions.
• 52. Structure of an Unknown d-Hexose.
• 53. Fatty Acid Content of Commercial Cooking Oils.
• 54. Structure of an Unknown Dipeptide.
• 55. Multistep Synthesis of Benzilic Acid from Benzaldehyde.
• 56. Using the Chemical Literature in an Organic Synthesis.
• 57. A Research Project in Organic Chemistry. III. MINILABS.
• 1. Making Useful Laboratory Items.
• 2. Extraction of Iodine by Dichloromethane.
• 3. Purification of an Unknown Compound by Recrystallization.
• 4. Developing and Testing a Hypothesis.
• 5. Preparation of Acetate Esters.
• 6. Gas Chromatographic Analysis of Commercial Xylene.
• 7. Isolation of Caffeine from No-Doz Tablets.
• 8. A Missing-Label Puzzle.
• 9. Paper Chromatography of Dyes in Commercial Drink Mixes.
• 10. Gas Chromatographic Analysis of an Essential Oil from Orange Peel.
• 11. Identification of an Unknown Felt-Tip-Pen Ink by TLC.
• 12. Optical Rotation of Turpentine.
• 13. The Structures of Organic Molecules.
• 14. Who Else Has My Compound?
• 15. Isomers and Molecular Structure.
• 16. Reactivities of Alkyl Halides in Nucleophilic Substitution Reactions.
• 17. An SN1 Reaction of Bromotriphenylmethane.
• 18. Preparation and Properties of a Gaseous Alkene.
• 19. Addition of Iodine to a-Pinene.
• 20. Unsaturation in Commercial Products.
• 21. Free-Radical Stability.
• 22. The Nylon Rope Trick.
• 23. Nucleophilic Substitution Rates of Alcohols.
• 24. Photoreduction of Benzophenone.
• 25. Oxidation of Alcohols by Potassium Permanganate.
• 26. Preparation of a Fluorescent Dye.
• 27. Diels-Alder Reaction of Maleic Anhydride and Furan.
• 28. Identification of an Unknown Arene by NMR Spectrometry.
• 29. Interpretation of a Mass Spectrum.
• 30. Nitration of Naphthalene.
• 31. Preparation of Carbocations by the Friedel-Crafts Reaction.
• 32. Air Oxidation of Fluorene to 9-Fluorenone.
• 33. A Nucleophilic Addition-Elimination Reaction of Benzil.
• 34. Preparation of Aldol Condensation Products.
• 35. A Spontaneous Reaction of Benzaldehyde.
• 36. Acid-Base Strengths of Organic Compounds.
• 37. Hydrolysis Rates of Esters.
• 38. Preparation of Benzamide.
• 39. Synthesis of Dimedone Derivatives of Benzaldehyde.
• 40. A Diazonium Salt Reaction of 2-Aminobenzoic Acid.
• 41. Beckmann Rearrangement of Benzophenone Oxime.
• 42. Dyeing with Indigo.
• 43. Reaction of Monosaccharides with Phenols.
• 44. Extraction of Trimyristin from Nutmeg.
• 45. Preparation of a Soap Using a Phase-Transfer Catalyst.
• 46. Isolation of a Protein from Milk. IV. QUALITATIVE ORGANIC ANALYSIS. An Overview of Qual Organic. Preliminary Work. Purification. Measurement of Physical Constants. Physical Examination. Ignition Test. Classification. Solubility Tests. Classification Tests. Spectral Analysis. Infrared Spectra. NMR Spectra. Identification. List of Possibilities. Additional Tests and Data. Preparation of Derivatives. Exercises. V. THE OPERATIONS. A. Basic Operations. Cleaning and Drying Glassware. Using Specialized Glassware. Using Glass Rod and Tubing. Weighing. Measuring Volume. Making Transfers. B. Operations for Conducting Chemical Reactions. Heating. Cooling. Temperature Monitoring. Mixing. Addition of Reactants. C. Separation Operations. Gravity Filtration. Vacuum Filtration. Centrifugation. Extraction. Evaporation. Steam Distillation. Column Chromatography. Thin-Layer Chromatography. Paper Chromatography. D. Washing and Drying Operations. Washing Liquids. Drying Liquids. Drying Solids. Drying and Trapping Gases. E. Purification Operations. Recrystallization. Sublimation. Simple Distillation. Vacuum Distillation. Fractional Distillation. F. Measuring Physical Constants. Melting Point. Boiling Point. Refractive Index. Optical Rotation. G. Instrumental Analysis. Gas Chromatography. High-Performance Liquid Chromatography. Infrared Spectrometry. Nuclear Magnetic Resonance Spectrometry. Ultraviolet-Visible Spectrometry. Mass Spectrometry. Appendixes and Bibliography. Index.
• (source: Nielsen Book Data)

This practical laboratory text provides a thorough introduction to the core operations in the organic lab in addition to a comprehensive selection of microscale experiments. Its unique problem-solving approach encourages students to think in the laboratory by solving a scientific problem in the process of carrying out each experiment. This product is available in Catalyst, our custom lab database.
(source: Nielsen Book Data)

• Chapter One: Introduction. Chapter Two: Safety. Chapter Three: Introduction to Microscale Organic Laboratory Equipment and Techniques. Chapter Four: Determination of Physical Properties. Chapter Five: Microscale Laboratory Techniques. Chapter Six: Microscale Organic Laboratory Experiments. Chapter Seven: Sequential Syntheses: The Transition from Macro to Micro. Chapter Eight: Spectroscopic Identification of Organic Compounds. Chapter Nine: Qualitative Identification of Organic Compounds. Chapter Ten (Online): Advanced Microscale Organic Laboratory Experiments.
• (source: Nielsen Book Data)

This is a laboratory text for the mainstream organic chemistry course taught at both two and four year schools, featuring both microscale experiments and options for scaling up appropriate experiments for use in the macroscale lab. It provides complete coverage of organic laboratory experiments and techniques with a strong emphasis on modern laboratory instrumentation, a sharp focus on safety in the lab, excellent pre- and post-lab exercises, and multi-step experiments. Notable enhancements to this new edition include inquiry-driven experimentation, validation of the purification process, and the implementation of greener processes (including microwave use) to perform traditional experimentation.
(source: Nielsen Book Data)

During the last two decades the photochemistry of organic molecules has grown into an important and pervasive branch of organic chemistry. In "Modern Molecular Photochemistry", the author brings students up to date with the advances in this field - the development of the theory of photoreactions, the utilization of photoreactions in synthetic sequences, and the advancement of powerful laser techniques to study the mechanisms of photoreactions.
(source: Nielsen Book Data)

"Modern Projects and Experiments in Organic Chemistry" helps instructors turn their organic chemistry laboratories into places of discovery and critical thinking. In addition to traditional experiments, the manual offers a variety of inquiry based experiments and multi week projects, giving students a better understanding of how lab work is actually accomplished. Instead of simply following directions, students learn how to investigate the experimental process itself. There are two versions of the manual, each tailored to specific laboratory equipment. In terms of content they are identical: "Miniscale and Standard Taper Microscale" (0716797798) and "Miniscale and Williamson Microscal" (0716739216). Upgraded from "Experimental Organic Chemistry", features include: custom publishing option (instructors can devise the lab manual they want); eight new inquiry based experiments which increase the manual's overall emphasis on active learning; five new multi week projects; five new first term projects (there are now nine for each term) which make it possible for instructors to plan an entire course around the project approach; and new pre-lab and post-lab questions.
(source: Nielsen Book Data)

• Foreword.Preface.List of Contributors.1 Rhodium-Catalyzed Asymmetric Hydrogenation (Yongxiang Chi, Wenjun Tang, and Xumu Zhang).1.1 Introduction.1.2 Chiral Phosphorous Ligands.1.3 Applications of Chiral Phosphorous Ligands in Rhodium-Catalyzed Asymmetric Hydrogenation.1.4 Conclusion.1.5 References.2 Rhodium-Catalyzed Hydroborations and Related Reactions (John M. Brown).2.1 Introduction.2.2 General Advances in Catalytic Hydroboration.2.3 Advances in Asymmetric Hydroboration.2.4 Catalytic Diboration of Alkenes.2.5 Summary and Conclusions.2.6 References.3 Rhodium(I)-Catalyzed Asymmetric Addition of Organometallic Reagents to Electron-Deficient Olefins (Kazuhiro Yoshida and Tamio Hayashi).3.1 Introduction.3.2 Addition of Organoboron Reagents to alpha, beta-Unsaturated Ketones.3.3 Mechanism.3.4 Addition of Organoboron Reagents to Other Electron-Deficient Olefins.3.5 Addition of Organotin and -silicon Reagents.3.6 New Aspects of Addition of Organoboron and -titanium Reagents.3.7 Outlook.3.8 References.4 Recent Advances in Rhodium(I)-Catalyzed Asymmetric Olefin Isomerization and Hydroacylation Reactions (Gregory C. Fu).4.1 Rhodium(I)-Catalyzed Asymmetric Isomerization of Olefins.4.2 Rhodium(I)-Catalyzed Asymmetric Hydroacylation of Olefins and Alkynes with Aldehydes.4.3 References.5 Stereoselective Rhodium(I)-Catalyzed Hydroformylation and Silylformylation Reactions and their Application to Organic Synthesis (James L. Leighton).5.1 Introduction.5.2 Hydroformylation.5.3 Silylformylation.5.4 Conclusion.5.5 References.6 Carbon-Carbon Bond-Forming Reactions Starting from Rh-H or Rh-Si Species (Isamu Matsuda).6.1 Introduction.6.2 Background.6.3 Design of Reactions Starting from Insertion into a Rh-H Bond.6.4 Design of Reactions Starting from Insertion into a Rh-Si Bond.6.5 Conclusion.6.6 References.7 Rhodium(I)-Catalyzed Cycloisomerization and Cyclotrimerization Reactions (Masaki Fujiwara and Iwao Ojima).7.1 Introduction.7.2 Carbocyclization.7.3 Cascade Carbocyclization.7.4 Carbonylative Carbocyclization.7.5 Conclusion.7.6 References.8 The Rhodium(I)-Catalyzed Alder-Ene Reaction (Kay M. Brummond and Jamie M. McCabe).8.1 Introduction.8.2 Diene Alder-Ene Reactions.8.3 Enyne Alder-Ene Reactions.8.4 Allenyne Alder-Ene Reactions.8.5 Kinetic Resolution.8.6 Other Rhodium-Catalyzed Ene-Type Reactions.8.7 Conclusion.8.8 References.9 Rhodium-Catalyzed Nucleophilic Ring Cleaving Reactions of Allylic Ethers and Amines (Keith Fagnou).9.1 Introduction.9.2 Seminal Work.9.3 Asymmetric Reactions with Oxabicyclic Alkenes.9.4 Azabicyclic Alkenes.9.5 Properties of the PPF-PtBu2 Ligand.9.6 Mechanistic Working Model.9.7 Vinyl Epoxides.9.8 Conclusion.9.9 References.10 Rhodium(I)-Catalyzed Allylic Substitution Reactions and their Applications to Target Directed Synthesis (David K. Leahy and P. Andrew Evans).10.1 Introduction.10.2 Regioselective Rhodium-Catalyzed Allylic Alkylation.10.3 Enantiospecific Rhodium-Catalyzed Allylic Alkylation.10.4 Enantioselective Rhodium-Catalyzed Allylic Alkylations.10.5 Conclusion.10.6 References.11 Rhodium(I)-Catalyzed [2+2+1] and [4+1] Carbocyclization Reactions (Nakcheol Jeong).11.1 General Introduction to Rhodium-Mediated Carbocyclizations.11.2 [2+2+1] Carbocyclization.11.3 [4+1] Carbocyclization.11.4 Conclusion.11.5 References.12 Rhodium(I)-Catalyzed [4+2] and [4+2+2] Carbocyclizations (John E. Robinson).12.1 Introduction.12.2 Rhodium(I)-Catalyzed [4+2] Carbocyclization Reactions.12.3 Rhodium(I)-Catalyzed [4+2+2] Carbocyclization Reactions.12.4 References.13 Rhodium(I)-Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis (Paul A. Wender, Gabriel G. Gamber, and Travis J. Williams).13.1 Introduction.13.2 Cycloaddition Approaches to Seven-Membered Rings.13.3 Design of a Transition Metal-Catalyzed [5+2] Cycloaddition of Vinylcyclopropanes and PI-Systems.13.4 Intramolecular [5+2] Cycloadditions of VCPs.13.5 Intermolecular [5+2] Cycloadditions of VCPs and Alkynes.13.6 Cycloaddition Approaches for Eight-Membered Ring Synthesis.13.7 Design and Development of [6+2] Cycloadditions of Vinylcyclobutanones.13.8 Design and Development of Multi-component [5+2+1] Cycloadditions of VCPs, Alkynes, and CO.13.9 Conclusion.13.10 References.14 Rhodium(II)-Stabilized Carbenoids Containing Both Donor and Acceptor Substituents (Huw M.L. Davies and Abbas M. Walji).14.1 Introduction.14.2 Cyclopropanation.14.3 [3+4] Cycloaddition of Vinyl Carbenoids.14.4 [3+2] Cycloaddition of Vinyl Carbenoids.14.5 Ylide Transformations.14.6 Si-H Insertion.14.7 C-H Activation by Carbenoid-Induced C-H Insertion.14.8 References.15 Chiral Dirhodium(II) Carboxamidates for Asymmetric Cyclopropanation and Carbon-Hydrogen Insertion Reactions (Michael P. Doyle).15.1 Introduction.15.2 Catalytic Asymmetric Cyclopropanation and Cyclopropenation.15.3 Catalytic Asymmetric Carbon-Hydrogen Insertion.15.4 Summary.15.5 References.16 Cyclopentane Construction by Rhodium(II)-Mediated Intramolecular C-H Insertion (Douglass F. Taber and Pramod V. Joshi).16.1 Introduction.16.2 Background: Cyclization versus Elimination.16.3 Beginnings of a Computational Approach.16.4 Comparing and Contrasting Rhodium Catalysts: Four Dimensions of Reactivity.16.5 Design of an Enantioselective Catalyst.16.6 Conclusion.16.7 References.17 Rhodium(II)-Catalyzed Oxidative Amination (Christine G. Espino and Justin Du Bois).17.1 Introduction.17.2 Background.17.3 Intermolecular C-H Amination with Rhodium(II) Catalysts.17.4 Intermolecular C-H Amination with Other Metals.17.5 Intramolecular C-H Amination with Rhodium(II) Catalysts.17.6 Rhodium(II)-Catalyzed Olefin Aziridination.17.7 Enantioselective C-H Insertion with Sulfamate Esters.17.8 Mechanistic Investigations.17.9 Summary and Outlook for Rhodium(II)-Catalyzed Nitrene Transfer.17.10 Rhodium(II)-Catalyzed Olefin Diamination.17.11 Applications of C-H Amination in Synthesis.17.12 Conclusion.17.13 References.18 Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)-Catalyzed Carbene Transfer (Frederick G. West).18.1 Introduction.18.2 Oxonium Ylides.18.3 Ammonium Ylides.18.4 Conclusion.18.5 References.19 Rhodium(II)-Catalyzed 1,3-Dipolar Cycloaddition Reactions (Ruben M. Savizky and David J. Austin)19.1 Rhodium(II) in 1,3-Dipole Formation.19.2 Chemical Aspects of Rhodium-Mediated 1,3-Dipolar Cycloaddition.19.3 Applications of Rhodium(II)-Mediated 1,3-Dipolar Cycloaddition.19.4 Conclusion.19.5 References.Subject Index.
• (source: Nielsen Book Data)

Rhodium has proven to be an extremely useful metal due to its ability to catalyze an array of synthetic transformations, with quite often--unique selectivity. Hydrogenation, C--H activation, allylic substitution, and numerous other reactions are catalyzed by this metal, which presumably accounts for the dramatic increase in the number of articles that have recently emerged on the topic. P. Andrew Evans, the editor of this much--needed book, has assembled an internationally renowned team to present the first comprehensive coverage of this important area. The book features contributions from leaders in the field of rhodium--catalyzed reactions, and thereby provides a detailed account of the most current developments, including: * Rhodium--Catalyzed Asymmetric Hydrogenation (Zhang) * Rhodium--Catalyzed Hydroborations and Related Reactions (Brown) * Rhodium--Catalyzed Asymmetric Addition of Organometallic Reagents to Electron Deficient Olefins (Hayashi) * Recent Advances in Rhodium(I)--Catalyzed Asymmetric Olefin Isomerization and Hydroacylation Reactions (Fu) * Stereoselective Rhodium(I)--Catalyzed Hydroformylation and Silylformylation Reactions and Their Application to Organic Synthesis (Leighton) * Carbon--Carbon Bond--Forming Reactions Starting from Rh--H or Rh--Si Species (Matsuda) * Rhodium(I)--Catalyzed Cycloisomerization and Cyclotrimerization Reactions (Ojima) * The Rhodium(I)--Catalyzed Alder--ene Reaction (Brummond) * Rhodium--Catalyzed Nucleophilic Ring Cleaving Reactions of Allylic Ethers and Amines (Fagnou) * Rhodium(I)--Catalyzed Allylic Substitution Reactions and their Applications to Target Directed Synthesis (Evans) * Rhodium(I)--Catalyzed [2+2+1] and [4+1] Carbocyclization Reactions (Jeong) * Rhodium(I)--Catalyzed [4+2] and [4+2+2] Carbocyclizations (Robinson) * Rhodium(I)--Catalyzed [5+2], [6+2], and [5+2+1] Cycloadditions: New Reactions for Organic Synthesis (Wender) * Rhodium(II)--Stabilized Carbenoids Containing both Donor and Acceptor Substituents (Davies) * Chiral Dirhodium(II)Carboxamidates for Asymmetric Cyclopropanation and Carbon--Hydrogen Insertion Reactions (Doyle) * Cyclopentane Construction by Rhodium(II)--Mediated Intramolecular C--H Insertion (Taber) * Rhodium(II)--Catalyzed Oxidative Amination (DuBois) * Rearrangement Processes of Oxonium and Ammonium Ylides Formed by Rhodium(II)--Catalyzed Carbene--Transfer (West) * Rhodium(II)--Catalyzed 1,3--Dipolar Cycloaddition Reactions (Austin) Modern Rhodium--Catalyzed Organic Reactions is an essential reference text for researchers at all levels in the general area of organic chemistry. This book provides an invaluable overview of the most significant developments in this important area of research, and will no doubt be an essential text for researchers at academic institutions and professionals at pharmaceutical/agrochemical companies.
(source: Nielsen Book Data)