In Treatment season three continues to center around Dr. Paul Weston who continues to cope with the after-effects of his recent divorce, as well as his move to Brooklyn to continue his practice. In the midst of new emotional and physical challenges (including hand tremors he fears might be the onset of Parkinson's Disease, which killed his father), Paul will be treating three new patients, and will see a new therapist in New York City.

• Disc 1. Week 1. 1. Laura ; 2. Alex ; 3. Sophie ; 4. Jake & Amy ; 5. Gina / teleplay by Rodrigo Garcia ; directed by Rodrigo Garcia.

• Disc 2. Week 2. 6. Laura / teleplay by Amy Lippman ; directed by Rodrigo Garcia
• 7. Alex / teleplay by Bryan Goluboff ; directed by Rodrigo Garcia
• 8. Sophie / teleplay by Sarah Treem ; directed by Rodrigo Garcia
• 9. Jake & Amy / teleplay by William Merritt Johnson ; directed by Rodrigo Garcia
• 10. Gina / teleplay by Davey Holmes ; directed by Rodrigo Garcia.

• Disc 3. Week 3. 11. Laura / teleplay by Amy Lippman ; directed by Rodrigo Garcia
• 12. Alex / teleplay by Bryan Goluboff ; directed by Christopher Misiano
• 13. Sophie / teleplay by Sarah Treem ; directed by Christopher Misiano
• 14. Jake & Amy / teleplay by William Merritt Johnson ; directed by Christopher Misiano
• 1̀5. Gina / teleplay by Davey Holmes ; directed by Rodrigo Garcia.

• Disc 4. Week 4. 16. Laura / teleplay by Amy Lippman ; directed by Christopher Misiano
• 17. Alex / teleplay by Bryan Goluboff ; directed by Christopher Misiano
• 18. Sophie / teleplay by Sarah Treem ; directed by Rodrigo Garcia
• 19. Jake & Amy / teleplay by William Merritt Johnson ; directed by Rodrigo Garcia
• 20. Gina / teleplay by Davey Holmes ; directed by Rodrigo Garcia.

• Disc 5. Week 5. 21. Laura / teleplay by Amy Lippman ; directed by Rodrigo Garcia
• 22. Alex / teleplay by Bryan Goluboff ; directed by Paris Barclay
• 23. Sophie / teleplay by Sarah Treem ; directed by Paris Barclay
• 24. Jake & Amy / teleplay by William Merritt Johnson ; directed by Paris Barclay
• 25. Gina / teleplay by Davey Holmes ; directed by Rodrigo Garcia.

• Disc 6. Week 6. 26. Laura / teleplay by Amy Lippman ; directed by Paris Barclay
• 27. Alex / teleplay by Bryan Goluboff ; directed by Melanie Mayron
• 28. Sophie / teleplay by Sarah Treem ; directed by Melanie Mayron
• 29. Jake & Amy / teleplay by William Merritt Johnson ; directed by Paris Barclay
• 30. Gina / teleplay by Davey Holmes ; directed by Paris Barclay.

• Disc 7. Week 7. 31. Laura / teleplay by Amy Lippman ; directed by Melanie Mayron
• 32. Alex / written by Bryan Goluboff ; directed by Paris Barclay
• 33. Sophie / teleplay by Sarah Treem ; directed by Melanie Mayron
• 34. Jake & Amy / teleplay by William Merritt Johnson ; directed by Melanie Mayron
• 35. Gina / teleplay by Davey Holmes ; directed by Rodrigo Garcia.

• Disc 8. Week 8. 36. Laura / written by Amy Lippman ; directed by Paris Barclay
• 37. Alex / teleplay by Bryan Goluboff ; directed by Paris Barclay
• 38. Sophie / teleplay by Sarah Treem ; directed by Paris Barclay
• 39. Jake & Amy / teleplay by William Merritt Johnson ; directed by Paris Barclay
• 40. Gina / teleplay by Davey Holmes ; directed by Rodrigo Garcia.

• Disc 9. Week 9. 41. Sophie / teleplay by Sarah Treem ; directed by Melanie Mayron
• 42. Jake & Amy / teleplay by William Merritt Johnson and Sarah Treem ; directed by Melanie Mayron
• 43. Gina / teleplay by Amy Lippman ; directed by Paris Barclay, Rodrigo Garcia.

Paul is a therapist who exhibits great insight and confidence when treating his patients. But Paul suffers crippling insecurities and is counseled by his own therapist, Gina. Adding to his list of growing concerns, his wife Kate is overcome with feelings of neglect and resents competing for his attention. Paul's patients include a young doctor who is in love with Paul; a Navy pilot who is reevaluating his life after a failed mission in Iraq; a teenage gymnast with suicidal tendencies; and a passionate couple who are troubled in all other areas of their lives.