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Enzyme kinetics [electronic resource] : catalysis & control : a reference of theory and best-practice methods / by Daniel Purich.

Availability

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Author/Creator:
Purich, Daniel L.
Language:
English.
Publication date:
2010
Imprint:
San Diego, Calif. : Elsevier Academic ; Oxford : Elsevier Science [distributor], 2010.
Format:
  • Book
  • p. cm.
Contents:
  • Introduction to Enzyme Rate Processes
  • Active Sites & Their Chemical Properties
  • Fundamentals of Chemical Kinetics
  • Practical Aspects of Measuring Rates & Kinetic
  • Initial-Rate Kinetics of One-Substrate Enzyme-Catalyzed Reactions
  • Initial-Rate Kinetics of Multi-Substrate Enzyme-Catalyzed Reactions
  • Other Factors Influencing Enzyme Activity
  • Kinetic Behavior of Enzyme Inhibitors
  • Isotopic Probes of Biological Catalysis
  • Probing Fast Enzyme Processes
  • Regulatory Behavior of Enzymes
  • Single-Molecule Enzyme Kinetics
  • Force Generation in Mechanoenzyme Catalysis
  • On Keeping a Research Notebook
  • Steady-State Rate Equations for Selected One- & Two-Substrate Enzyme-Catalyzed Reactions
  • Summary of Enzyme Kinetic Mechanisms Abbreviations & Symbols References.
Summary:
Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. - Historical analysis of kinetic principles including advanced enzyme science - Provides both theoretical and practical measurements tools - Coverage of single molecular kinetics - Examination of force generation mechanisms - Discussion of organic and inorganic enzyme reactions.
Reproduction:
Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2010. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on July 13, 2010). Access may be restricted to users at subscribing institutions.
Contributor:
ScienceDirect (Online service)
Subjects:
ISBN:
9780123809247
012380924X

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