Pulsewidth determinations-- routine NMR and standard tests-- decoupling techniques-- dynamic NMR spectroscopy-- 1D-multipulse sequences-- NMR spectroscopy with selective pulses-- auxiliary reagents, quantitative determinations and reaction mechanism-- heteronuclear NMR spectroscopy-- the second dimension-- NMR spectroscopy with pulsed field gradients-- the third dimension.
(source: Nielsen Book Data)
This practical course aims to enable the reader to understand the field of NMR experiments for structure determination. The experiments featured have been chosen mainly because of their importance and general applicability. Three compounds have been chosen as the main demonstration samples - chloroform, ethyl crotonate and strychnine (which should be used as a sealed sample). A scheme has been adopted for the detailed description of the experiments, organized in the following specific sections: "Purpose" explains the idea and goal of the experiment and refers the user to related experiments; "Literature" presents references to the original publication and to improvements and/or sections in monographs and reviews; "Pulse Scheme and Phase Cycle" gives the pulse sequence in an instrument-independent graphic and self-explanatory form, and the phase cycles of the pulses and the receiver; "Acquisition" is the main section, with instructions on the sample to be used, the spectrometer configuration, the type of programme and the parameters necessary for the performance of the experiment; "Processing" describes how to treat the time-domain data; "Results" presents the spectrum obtained by following the procedure exactly; and "Comments" contains an explanation of the most important steps of the pulse sequence. In general, the conditions for the experiments have not been optimized. In all cases, the results are presented exactly as they were obtained, without cosmetic retouching; sometimes, the samples used even show impurities. (source: Nielsen Book Data)