Search results

90 results

View results as:
Number of results to display per page
Book
xvi, 523 pages, 53 variously numbered pages ; 28 cm
  • Chemistry for a sustainable future
  • The air we breathe
  • Protecting the ozone layer
  • The chemistry of global climate change
  • Energy from combustion
  • Water for life
  • Neutralizing the threat of acid rain
  • The fires of nuclear fission
  • Energy from electron transfer?
  • The world of polymers and plastics
  • Manipulating molecules and designing drugs
  • Nutrition : food for thought
  • Genetic engineering and the molecules of life
  • Appendix 1: Measure for measure : conversion factors and constants
  • Appendix 2: The power of exponents
  • Appendix 3: Clearing the logjam
  • Appendix 4: Answers to your turn questions not answered in text
  • Appendix 5: Answers to selected end-of-chapter questions indicated in color in the text
  • Glossary.
  • Chemistry for a sustainable future
  • The air we breathe
  • Protecting the ozone layer
  • The chemistry of global climate change
  • Energy from combustion
  • Water for life
  • Neutralizing the threat of acid rain
  • The fires of nuclear fission
  • Energy from electron transfer?
  • The world of polymers and plastics
  • Manipulating molecules and designing drugs
  • Nutrition : food for thought
  • Genetic engineering and the molecules of life
  • Appendix 1: Measure for measure : conversion factors and constants
  • Appendix 2: The power of exponents
  • Appendix 3: Clearing the logjam
  • Appendix 4: Answers to your turn questions not answered in text
  • Appendix 5: Answers to selected end-of-chapter questions indicated in color in the text
  • Glossary.
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD415 .C482 2015 Unknown
QD415 .C482 2015 Unknown
Book
xiii, 146 p. : ill. ; 24 cm
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
RS407 .D53 2014 Unknown
Book
xv, 458 pages : illustrations (some color) ; 25 cm
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
RS403 .G55 2014 Unknown
Book
1 v. (various pagings) : ill. (chiefly col.) ; 29 cm.
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD415 .V63 2013 Unknown
Book
xvii, 486 p. : ill., (some col.) ; 28 cm.
"Introduction to Bioorganic Chemistry and Chemical Biology integrates organic chemistry with biological concepts that are fundamental to biology, physiology, and medicine. This problems-driven textbook explains the chemical structures of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engines for life. It then applies organic chemistry to examine the central dogma of molecular biology. Biological macromolecules are rendered to reveal secondary structure and modern depictions of organic structures and mechanistic arrow-pushing will be familiar to all students who have taken an introductory course in organic chemistry"-- Provided by publisher.
"Introduction to Bioorganic Chemistry and Chemical Biology integrates organic chemistry with biological concepts that are fundamental to biology, physiology, and medicine. This problems-driven textbook explains the chemical structures of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engines for life. It then applies organic chemistry to examine the central dogma of molecular biology. Biological macromolecules are rendered to reveal secondary structure and modern depictions of organic structures and mechanistic arrow-pushing will be familiar to all students who have taken an introductory course in organic chemistry"-- Provided by publisher.
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD415 .V36 2013 Unknown
Book
1 v. (various pagings) : ill. (some col.) ; 29 cm.
  • The Foundations of Biochemistry
  • I. STRUCTURE AND CATALYSIS. Water
  • Amino Acids, Peptides, and Proteins
  • The Three-Dimensional Structure of Proteins
  • Protein Function
  • Enzymes
  • Carbohydrates and Glycobiology
  • Nucleotides and Nucleic Acids
  • DNA-Based Information Technologies
  • Lipids
  • Biological Membranes and Transport
  • Biosignaling
  • II. BIOENERGETICS AND METABOLISM. Bioenergetics and Biochemical Reaction Types
  • Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
  • Principles of Metabolic Regulation
  • The Citric Acid Cycle-- Fatty Acid Catabolism
  • Amino Acid Oxidation and the Production of Urea
  • Oxidative Phosphorylation and Photophosphorylation Oxidative Phosphorylation
  • Carbohydrate Biosynthesis in Plants and Bacteria
  • Lipid biosynthesis
  • Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
  • Hormonal Regulation and Integration of Mammalian Metabolism
  • III. INFORMATION PATHWAYS. Genes and Chromosomes
  • DNA Metabolism
  • RNA Metabolism
  • Protein Metabolism
  • Regulation of Gene Expression.
  • The Foundations of Biochemistry
  • I. STRUCTURE AND CATALYSIS. Water
  • Amino Acids, Peptides, and Proteins
  • The Three-Dimensional Structure of Proteins
  • Protein Function
  • Enzymes
  • Carbohydrates and Glycobiology
  • Nucleotides and Nucleic Acids
  • DNA-Based Information Technologies
  • Lipids
  • Biological Membranes and Transport
  • Biosignaling
  • II. BIOENERGETICS AND METABOLISM. Bioenergetics and Biochemical Reaction Types
  • Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway
  • Principles of Metabolic Regulation
  • The Citric Acid Cycle-- Fatty Acid Catabolism
  • Amino Acid Oxidation and the Production of Urea
  • Oxidative Phosphorylation and Photophosphorylation Oxidative Phosphorylation
  • Carbohydrate Biosynthesis in Plants and Bacteria
  • Lipid biosynthesis
  • Biosynthesis of Amino Acids, Nucleotides, and Related Molecules
  • Hormonal Regulation and Integration of Mammalian Metabolism
  • III. INFORMATION PATHWAYS. Genes and Chromosomes
  • DNA Metabolism
  • RNA Metabolism
  • Protein Metabolism
  • Regulation of Gene Expression.
Chemistry & ChemEng Library (Swain), Marine Biology Library (Miller)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Request at circulation desk
QD415 .L44 2013 Unknown On Reserve 2-hour loan
QD415 .L44 2013 Unknown On Reserve 2-hour loan
Status of items at Marine Biology Library (Miller)
Marine Biology Library (Miller) Status
Stacks
QD415 .L44 2013 Unknown
CHEM-183-01, CHEMENG-183-01, CHEMENG-283-01
Course
CHEM-183-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Course
CHEMENG-183-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Course
CHEMENG-283-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert

7. Biochemistry [2012]

Book
xxxii, 1054, [132] p. : ill. ; 28 cm.
  • Biochemistry: an evolving science
  • Protein composition and structure
  • Exploring proteins and proteomes
  • DNA, RNA, and the flow of genetic information
  • Exploring genes and genomes
  • Exploring evolution and bioinformatics
  • Hemoglobin: portrait of a protein in action
  • Enzymes: basic concepts and kinetics
  • Catalytic strategies
  • Regulatory strategies
  • Carbohydrates
  • Lipids and cell membranes
  • Membrane channels and pumps
  • Signal-transduction pathways
  • Metabolism: basic concepts and design
  • Glycolysis and gluconeogenesis
  • The citric acid cycle
  • Oxidative phosphorylation
  • The light reactions of photosynthesis
  • The calvin cycle and the pentose phosphate pathway
  • Glycogen metabolism
  • Fatty acid metabolism
  • Protein turnover and amino acid catabolism
  • The biosynthesis of amino acids
  • Nucleotide biosynthesis
  • The biosynthesis of membrane lipids and steroids
  • The integration of metabolism
  • DNA replication, repair, and recombination
  • RNA synthesis and processing
  • Protein synthesis
  • The control of gene expression in prokaryotes
  • The control of gene expression in eukaryotes
  • Sensory systems
  • The immune system
  • Molecular motors
  • Drug development.
  • Biochemistry: an evolving science
  • Protein composition and structure
  • Exploring proteins and proteomes
  • DNA, RNA, and the flow of genetic information
  • Exploring genes and genomes
  • Exploring evolution and bioinformatics
  • Hemoglobin: portrait of a protein in action
  • Enzymes: basic concepts and kinetics
  • Catalytic strategies
  • Regulatory strategies
  • Carbohydrates
  • Lipids and cell membranes
  • Membrane channels and pumps
  • Signal-transduction pathways
  • Metabolism: basic concepts and design
  • Glycolysis and gluconeogenesis
  • The citric acid cycle
  • Oxidative phosphorylation
  • The light reactions of photosynthesis
  • The calvin cycle and the pentose phosphate pathway
  • Glycogen metabolism
  • Fatty acid metabolism
  • Protein turnover and amino acid catabolism
  • The biosynthesis of amino acids
  • Nucleotide biosynthesis
  • The biosynthesis of membrane lipids and steroids
  • The integration of metabolism
  • DNA replication, repair, and recombination
  • RNA synthesis and processing
  • Protein synthesis
  • The control of gene expression in prokaryotes
  • The control of gene expression in eukaryotes
  • Sensory systems
  • The immune system
  • Molecular motors
  • Drug development.
Biology Library (Falconer), Chemistry & ChemEng Library (Swain)
Status of items at Biology Library (Falconer)
Biology Library (Falconer) Status
Stacks
QP514.2 .S66 2012 Unknown
QP514.2 .S66 2012 Unknown
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Request at circulation desk
QP514.2 .S66 2012 Unknown On Reserve 2-hour loan
QP514.2 .S66 2012 Unknown On Reserve 2-hour loan
QP514.2 .S66 2012 Unknown On Reserve 2-hour loan
QP514.2 .S66 2012 Unknown On Reserve 2-hour loan
CHEM-183-01, CHEMENG-150-01, CHEMENG-183-01, CHEMENG-283-01
Course
CHEM-183-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Course
CHEMENG-150-01 -- Biochemical Engineering
Instructor(s)
Swartz, James Robert
Course
CHEMENG-183-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Course
CHEMENG-283-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Book
1 v. (various pagings) : ill. (chiefly col.), col. maps ; 28 cm.
  • Chemistry for a sustainable future
  • The air we breathe
  • Protecting the ozone layer
  • The chemistry of global warming
  • Energy, chemistry, and society
  • The water for life
  • Neutralizing the threat of acid rain
  • The fires of nuclear fission
  • Energy from electron transfer
  • The world of Polymers and plastics
  • Manipulating molecules and designing drugs
  • Nutrition: food for thought
  • Genetic engineering and the molecules of life.
  • Chemistry for a sustainable future
  • The air we breathe
  • Protecting the ozone layer
  • The chemistry of global warming
  • Energy, chemistry, and society
  • The water for life
  • Neutralizing the threat of acid rain
  • The fires of nuclear fission
  • Energy from electron transfer
  • The world of Polymers and plastics
  • Manipulating molecules and designing drugs
  • Nutrition: food for thought
  • Genetic engineering and the molecules of life.
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD415 .C482 2012 Unknown

9. Biochemistry [2011]

Book
xxv, 1428, 53 p. : ill. (some col.) ; 29 cm.
  • Guide to Media Resources xvi PART I INTRODUCTION AND BACKGROUND 1 1 Life 3 2 Aqueous Solutions 40 3 Thermodynamic Principles: A Review 52 PART II BIOMOLECULES 65 4 Amino Acids 67 5 Nucleic Acids, Gene Expression, and Recombinant DNA Technology 82 6 Techniques of Protein and Nucleic Acid Purifications 129 7 Covalent Structures of Proteins and Nucleic Acids 163 8 Three-Dimensional Structures of Proteins 221 9 Protein Folding, Dynamics, and Structural Evolution 278 10 Hemoglobin: Protein Function in Microcosm 323 11 Sugars and Polysaccharides 359 12 Lipids and Membranes 386 PART III MECHANISMS OF ENZYME ACTION 467 13 Introduction to Enzymes 469 14 Rates of Enzymatic Reactions 482 15 Enzymatic Catalysis 506 PART IV METABOLISM 557 16 Introduction to Metabolism 559 17 Glycolysis 593 18 Glycogen Metabolism 638 19 Signal Transduction 671 20 Transport through Membranes 744 21 Citric Acid Cycle 789 22 Electron Transport and Oxidative Phosphorylation 823 23 Other Pathways of Carbohydrate Metabolism 871 24 Photosynthesis 901 25 Lipid Metabolism 940 26 Amino Acid Metabolism 1019 27 Energy Metabolism: Integration and Organ Specialization 1088 28 Nucleotide Metabolism 1107 PART V EXPRESSION AND TRANSMISSION OF GENETIC INFORMATION 1143 29 Nucleic Acid Structures 1145 30 DNA Replication, Repair, and Recombination 1173 31 Transcription 1260 32 Translation 1338 33 Viruses: Paradigms for Cellular Function W-1 34 Eukaryotic Gene Expression W-53 35 Molecular Physiology W-165 (Chapters 33--35 are available on our website, www.wiley.com/college/voet ) xii.
  • (source: Nielsen Book Data)
The "Gold Standard" in Biochemistry text books, Biochemistry 4e , is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.
(source: Nielsen Book Data)
  • Guide to Media Resources xvi PART I INTRODUCTION AND BACKGROUND 1 1 Life 3 2 Aqueous Solutions 40 3 Thermodynamic Principles: A Review 52 PART II BIOMOLECULES 65 4 Amino Acids 67 5 Nucleic Acids, Gene Expression, and Recombinant DNA Technology 82 6 Techniques of Protein and Nucleic Acid Purifications 129 7 Covalent Structures of Proteins and Nucleic Acids 163 8 Three-Dimensional Structures of Proteins 221 9 Protein Folding, Dynamics, and Structural Evolution 278 10 Hemoglobin: Protein Function in Microcosm 323 11 Sugars and Polysaccharides 359 12 Lipids and Membranes 386 PART III MECHANISMS OF ENZYME ACTION 467 13 Introduction to Enzymes 469 14 Rates of Enzymatic Reactions 482 15 Enzymatic Catalysis 506 PART IV METABOLISM 557 16 Introduction to Metabolism 559 17 Glycolysis 593 18 Glycogen Metabolism 638 19 Signal Transduction 671 20 Transport through Membranes 744 21 Citric Acid Cycle 789 22 Electron Transport and Oxidative Phosphorylation 823 23 Other Pathways of Carbohydrate Metabolism 871 24 Photosynthesis 901 25 Lipid Metabolism 940 26 Amino Acid Metabolism 1019 27 Energy Metabolism: Integration and Organ Specialization 1088 28 Nucleotide Metabolism 1107 PART V EXPRESSION AND TRANSMISSION OF GENETIC INFORMATION 1143 29 Nucleic Acid Structures 1145 30 DNA Replication, Repair, and Recombination 1173 31 Transcription 1260 32 Translation 1338 33 Viruses: Paradigms for Cellular Function W-1 34 Eukaryotic Gene Expression W-53 35 Molecular Physiology W-165 (Chapters 33--35 are available on our website, www.wiley.com/college/voet ) xii.
  • (source: Nielsen Book Data)
The "Gold Standard" in Biochemistry text books, Biochemistry 4e , is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Request at circulation desk
QP514.2 .V64 2011 Unknown On Reserve 2-hour loan
QP514.2 .V64 2011 Unknown On Reserve 2-hour loan
CHEM-183-01, CHEMENG-183-01, CHEMENG-283-01
Course
CHEM-183-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Course
CHEMENG-183-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Course
CHEMENG-283-01 -- Biochemistry II
Instructor(s)
Dunn, Alexander Robert
Book
ix, 233 p. : ill. ; 25 cm.
  • Biological Molecules-- Spectroscopy-- Mass Spectrometry-- Hydrodynamics-- Thermodynamics and Interactions-- Kinetics-- Chromatography and Electrophoresis-- Single Molecules-- Subject Index.
  • (source: Nielsen Book Data)
Biophysical Chemistry covers the physical chemistry of biological macromolecules and the experimental techniques used to study them. Topics covered include: an introduction to biological molecules; spectroscopy, mass spectrometry and hydrodynamics of macromolecules; a "bluffer's guide" to molecular thermodynamics; biomolecular kinetics; chromatography and electrophoresis; and single-molecule methods. The easily digestible, pragmatic approach captures the reader with the fascinating challenges the subject poses for theoretical and experimental scientists. This book will be ideal for early undergraduates studying chemical or physical sciences and will act as a basis for more advanced study. Students in other areas of biological sciences will appreciate the less intimidating approach to physical chemistry as demonstrated here. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.
(source: Nielsen Book Data)
  • Biological Molecules-- Spectroscopy-- Mass Spectrometry-- Hydrodynamics-- Thermodynamics and Interactions-- Kinetics-- Chromatography and Electrophoresis-- Single Molecules-- Subject Index.
  • (source: Nielsen Book Data)
Biophysical Chemistry covers the physical chemistry of biological macromolecules and the experimental techniques used to study them. Topics covered include: an introduction to biological molecules; spectroscopy, mass spectrometry and hydrodynamics of macromolecules; a "bluffer's guide" to molecular thermodynamics; biomolecular kinetics; chromatography and electrophoresis; and single-molecule methods. The easily digestible, pragmatic approach captures the reader with the fascinating challenges the subject poses for theoretical and experimental scientists. This book will be ideal for early undergraduates studying chemical or physical sciences and will act as a basis for more advanced study. Students in other areas of biological sciences will appreciate the less intimidating approach to physical chemistry as demonstrated here. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD476.2 .C66 2011 Unknown
Book
xxii, 289 p., 4 p. of plates : ill. (some col.) ; 24 cm
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
RS201 .N35 N35 2011 Unknown
Book
xxiii, 1044, 53, 30 p. : ill. (some col.) ; 27 cm.
Renowned for its student-friendly writing style and fresh perspective, John McMurry's ORGANIC CHEMISTRY WITH BIOLOGICAL APPLICATIONS offers full coverage of the foundations of organic chemistry--enhanced by biological examples throughout. Based on user feedback, McMurry continues to discuss the organic chemistry of biological pathways and now adds two dozen additional organic chemistry topics, as well as new problems, new illustrations, and new essays. Media integration with Organic OWL, a customizable online learning system and assessment tool, reduces faculty workload, facilitates instruction, and helps students master concepts through tutorials, simulations, and algorithmically generated homework questions.
(source: Nielsen Book Data)
Renowned for its student-friendly writing style and fresh perspective, John McMurry's ORGANIC CHEMISTRY WITH BIOLOGICAL APPLICATIONS offers full coverage of the foundations of organic chemistry--enhanced by biological examples throughout. Based on user feedback, McMurry continues to discuss the organic chemistry of biological pathways and now adds two dozen additional organic chemistry topics, as well as new problems, new illustrations, and new essays. Media integration with Organic OWL, a customizable online learning system and assessment tool, reduces faculty workload, facilitates instruction, and helps students master concepts through tutorials, simulations, and algorithmically generated homework questions.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Permanent reserve
QD251.3 .M365 2011 Unknown
Book
xxvi, 590 p. : col. ill. ; 27 cm.
  • PART 1 - BIOCHEMICAL THERMODYNAMICS -- 1. The First Law -- 2. The Second Law -- 3. Phase Equilibria -- 4. Chemical Equilibrium -- 5. Thermodynamics of Ion and Electron Transport -- PART 2- THE KINETICS OF LIFE PROCESSES -- 6. The Rates of Reactions -- 7. Accounting for the Rate Laws -- 8. Complex Biochemical Processes -- PART 3 - BIOMOLECULAR STRUCTURE -- 9. Microscopic Systems and Quantization -- 10. The Chemical Bond -- 11. Macromolecules and Self-Assembly -- PART 4 - BIOMOLECULAR SPECTROSCOPY -- 12. Optical Techniques and Photobiology -- 14. Magnetic Resonance.
  • (source: Nielsen Book Data)
Physical chemistry lies at the heart of the behaviour of those macromolecules and molecular assemblies that have vital roles in all living organisms. Physical principles determine the stability of proteins and nucleic acids, the rate at which biochemical reactions proceed, the transport of molecules across biological molecules; they allow us to describe structure and reactivity in complex biological systems, and make sense of how these systems operate. Physical Chemistry for the Life Sciences provides a balanced presentation of the concepts of physical chemistry, and their extensive applications to biology and biochemistry. It is written to straddle the worlds of physical chemistry and the life sciences and to show students how the tools of physical chemistry can elucidate and illuminate biological questions. Opening with a suite of chapters on Biochemical Thermodynamics, with a focus on energy conversion in biological cells and the factors that stabilize proteins, nucleic acids, and cell membranes, the book goes on to explore the Kinetics of Life Processes, examining the rates of chemical reactions, how rates can help characterise the mechanism of a reaction, and how enzymes affect reaction rates. A third section, Biomolecular Structure, looks at how concepts of physical chemistry can be used to establish those 'rules' that govern the assembly of complex biological structures, while the final section, Biomolecular Spectroscopy, describes the major techniques in biochemistry that are being applied to help us to explore biochemical processes and systems ever further. Physical Chemistry for the Life Sciences places emphasis on clear explanations of difficult concepts, with an eye toward building insight into biochemical phenomena. An extensive range of learning features, including worked examples, illustrations, self-tests, and case studies, support student learning throughout, while special attention is given to providing extensive help to students with those mathematical concepts and techniques that are so central to a sound understanding of physical chemistry. Balancing clarity and rigor of exposition of basic concepts with extensive discussion of biological techniques and processes, Physical Chemistry for the Life Sciences is the perfect resource for every life science student who seeks to master those essentials of physical chemistry that underpin life itself. Online Resource Centre For students: - Web links for each chapter, pointing students to interesting sources of related information and data, to facilitate self-directed learning - A list of key equations for each chapter, to help students revise and master the key mathematical concepts that underpin the subject - Living graphs, which present graphs from the text in interactive format, and enable students to strengthen their learning by manipulating key variables and exploring the consequeneces - Three-dimensional, interactive models of the biomolecules appearing in the end-of-book atlas of structures For registered adopters of the book: Figures in electronic format.
(source: Nielsen Book Data)
  • PART 1 - BIOCHEMICAL THERMODYNAMICS -- 1. The First Law -- 2. The Second Law -- 3. Phase Equilibria -- 4. Chemical Equilibrium -- 5. Thermodynamics of Ion and Electron Transport -- PART 2- THE KINETICS OF LIFE PROCESSES -- 6. The Rates of Reactions -- 7. Accounting for the Rate Laws -- 8. Complex Biochemical Processes -- PART 3 - BIOMOLECULAR STRUCTURE -- 9. Microscopic Systems and Quantization -- 10. The Chemical Bond -- 11. Macromolecules and Self-Assembly -- PART 4 - BIOMOLECULAR SPECTROSCOPY -- 12. Optical Techniques and Photobiology -- 14. Magnetic Resonance.
  • (source: Nielsen Book Data)
Physical chemistry lies at the heart of the behaviour of those macromolecules and molecular assemblies that have vital roles in all living organisms. Physical principles determine the stability of proteins and nucleic acids, the rate at which biochemical reactions proceed, the transport of molecules across biological molecules; they allow us to describe structure and reactivity in complex biological systems, and make sense of how these systems operate. Physical Chemistry for the Life Sciences provides a balanced presentation of the concepts of physical chemistry, and their extensive applications to biology and biochemistry. It is written to straddle the worlds of physical chemistry and the life sciences and to show students how the tools of physical chemistry can elucidate and illuminate biological questions. Opening with a suite of chapters on Biochemical Thermodynamics, with a focus on energy conversion in biological cells and the factors that stabilize proteins, nucleic acids, and cell membranes, the book goes on to explore the Kinetics of Life Processes, examining the rates of chemical reactions, how rates can help characterise the mechanism of a reaction, and how enzymes affect reaction rates. A third section, Biomolecular Structure, looks at how concepts of physical chemistry can be used to establish those 'rules' that govern the assembly of complex biological structures, while the final section, Biomolecular Spectroscopy, describes the major techniques in biochemistry that are being applied to help us to explore biochemical processes and systems ever further. Physical Chemistry for the Life Sciences places emphasis on clear explanations of difficult concepts, with an eye toward building insight into biochemical phenomena. An extensive range of learning features, including worked examples, illustrations, self-tests, and case studies, support student learning throughout, while special attention is given to providing extensive help to students with those mathematical concepts and techniques that are so central to a sound understanding of physical chemistry. Balancing clarity and rigor of exposition of basic concepts with extensive discussion of biological techniques and processes, Physical Chemistry for the Life Sciences is the perfect resource for every life science student who seeks to master those essentials of physical chemistry that underpin life itself. Online Resource Centre For students: - Web links for each chapter, pointing students to interesting sources of related information and data, to facilitate self-directed learning - A list of key equations for each chapter, to help students revise and master the key mathematical concepts that underpin the subject - Living graphs, which present graphs from the text in interactive format, and enable students to strengthen their learning by manipulating key variables and exploring the consequeneces - Three-dimensional, interactive models of the biomolecules appearing in the end-of-book atlas of structures For registered adopters of the book: Figures in electronic format.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QP517 .P49 A86 2011 Unknown
Book
ix, 238 p. : ill. (some col.) ; 25 cm.
  • 1 - Introductory notes-- Inspiring hierarchical-- Encoding instructive-- Starting lowest-- Picturing biological-- 2 - Re-cycling hereditary-- Coding dual-- Deoxyribonucleic-- Building up in two-- Keeping in shape-- Priming topological-- Re-sequencing basic-- Choosing the fittest-- Evolving diverse-- Primary motifs-- Gluing universal-- Alienating axial-- Fixing spatial-- Hinting geometric: secondary motifs-- Crossing double-- Reporting visible-- Translating symmetrical-- Extending cohisive-- Sharing mutual-- Multiplying traversal-- Tiling square-- Scaffolding algorithmic-- Pursuing autonomous-- Lengthening to shorten-- Gathering to limit-- Assigning arbitrary-- Synchronizing local-- Prescribing general-- Adding up to third-- Wrapping to shut-- Framing to classify-- Outlook-- References-- 3- Re-caging within-- Enclosing to deliver-- Transporting foreign-- Fitting flat and straight-- Spiralling along-- Packing out and in-- Spooling around-- Tunnelling through-- Escaping walled-- Capturing on and off-- Storing exchangeable-- Reacting nano-- Clustering spherical-- Contriving consistent-- Scaling hosting-- Following linear-- Channelling inner-- Converting outer-- Repairing from inside-- Uninviting levy-- Necessitating exterior-- Antagonising dressing-- Buffering masking-- Renting occasional-- Phasing wet-- Facing concentric-- Encircling between-- Singling out unique-- Sharing the balance-- Driving symmetrical-- Sealing annular-- Outlook-- References-- 4 - Re-assembling multiple-- Keeping all in touch-- Unravelling the essential-- Winding three in one-- Aligning stagger-- Tapering polar-- Branching and stretching-- Replicating apparent-- Scrapping refusal-- Tempting compatible-- Likening synthetic-- Recovering intelligent-- Restoring available-- Prompting longitudinal-- Invoking granted-- Reposing modular-- Displacing coil-- Settling lateral-- Bundling exclusive-- Permitting distinctive-- Inviting captive-- Clearing limiting-- Equilibrating transitional-- Extracting minimal-- Gambling beyond-- Guiding proliferative-- Feeding proximate-- Rooting renewal-- Accepting inescapable-- Patterning positional-- Relating interfacial-- Grafting integral-- Outlook-- References-- 5 - Concluding remarks-- Learning fluent-- Parsing semantic-- Drawing pragmatic-- 6 - Revealing contributory.
  • (source: Nielsen Book Data)
The progress of today's science and technology encounters an increasing demand for finer and more efficiently performing materials with properties superior over those of current and hence ageing devices. Whether this is concerned with electronics or drug delivery, cancer diagnostics or alternative energy sources, the search for means of miniaturizing the existing materials or devising fundamentally new components with higher capacities appears to be relentless. A saving solution to this is widely proposed as the design and fabrication of nanostructures, molecular architectures with dimensions featured below 100 nm. Replicating Nature's designs faithfully reproduced over millions of years provides perhaps the most straightforward route to success. Nature offers examples of nanodefined self-assemblies in virtually all levels of biological organization. However explicit guidance to the fabrication of functional or specialist nanostructures is of paramount importance. Nanotechnology is often referred to as building nanoscale structures from bottom up. However, while it is visually clear what is at "up" little is given and understood what is at the "bottom". This new book gives the notion of and provides rules for building nanostructures from basics - the very bottom. The main objective of this publication is to bring together contemporary approaches for designing nanostructures that employ naturally derived self-assembling motifs as synthetic platforms. The book has been written to satisfy the demands that motivate the search for and principles that prove to help the design of novel nanostructures. The overall goal is to compile the existing understanding of rules that govern biomolecular self-assembly into a practical guide to molecular nanotechnology. It is written in the shape of a review referenced as fully as permissible within the context of biomolecular design, which forms a general trend throughout. The volume is composed of three core chapters focusing on three prominent topics of applied nanotechnology where the role of nanodesign is predominant. The three key areas from which popular highlights can be drawn are: -employing the genetic repository, DNA, for creating various geometric nanoscale objects and patterns -the empirical pursuit of an artificial virus, a magic bullet in gene therapy -designing artificial extracellular matrices for regenerative medicine Specific applications that arise from designed nanoscale assemblies as well as fabrication and characterization techniques are of secondary importance and whenever they appear serve as progress and innovation highlights. The book takes an unconventional approach in delivering material of this kind. It does not lead straight to applications or methods as most nanotechnology works tend to do, but instead it focuses on the initial and primary aspect of "nano" rather than on "technology". Nanodesign is unique in its own field - illustrations are essential and the cohort of brilliant bioinspired designs reported to date form a major part of the publication. In addition, key bibliographic references are covered as fully as possible. A special appendix giving a short list of leading world laboratories engaged in bioinspired nanodesign is also included.
(source: Nielsen Book Data)
  • 1 - Introductory notes-- Inspiring hierarchical-- Encoding instructive-- Starting lowest-- Picturing biological-- 2 - Re-cycling hereditary-- Coding dual-- Deoxyribonucleic-- Building up in two-- Keeping in shape-- Priming topological-- Re-sequencing basic-- Choosing the fittest-- Evolving diverse-- Primary motifs-- Gluing universal-- Alienating axial-- Fixing spatial-- Hinting geometric: secondary motifs-- Crossing double-- Reporting visible-- Translating symmetrical-- Extending cohisive-- Sharing mutual-- Multiplying traversal-- Tiling square-- Scaffolding algorithmic-- Pursuing autonomous-- Lengthening to shorten-- Gathering to limit-- Assigning arbitrary-- Synchronizing local-- Prescribing general-- Adding up to third-- Wrapping to shut-- Framing to classify-- Outlook-- References-- 3- Re-caging within-- Enclosing to deliver-- Transporting foreign-- Fitting flat and straight-- Spiralling along-- Packing out and in-- Spooling around-- Tunnelling through-- Escaping walled-- Capturing on and off-- Storing exchangeable-- Reacting nano-- Clustering spherical-- Contriving consistent-- Scaling hosting-- Following linear-- Channelling inner-- Converting outer-- Repairing from inside-- Uninviting levy-- Necessitating exterior-- Antagonising dressing-- Buffering masking-- Renting occasional-- Phasing wet-- Facing concentric-- Encircling between-- Singling out unique-- Sharing the balance-- Driving symmetrical-- Sealing annular-- Outlook-- References-- 4 - Re-assembling multiple-- Keeping all in touch-- Unravelling the essential-- Winding three in one-- Aligning stagger-- Tapering polar-- Branching and stretching-- Replicating apparent-- Scrapping refusal-- Tempting compatible-- Likening synthetic-- Recovering intelligent-- Restoring available-- Prompting longitudinal-- Invoking granted-- Reposing modular-- Displacing coil-- Settling lateral-- Bundling exclusive-- Permitting distinctive-- Inviting captive-- Clearing limiting-- Equilibrating transitional-- Extracting minimal-- Gambling beyond-- Guiding proliferative-- Feeding proximate-- Rooting renewal-- Accepting inescapable-- Patterning positional-- Relating interfacial-- Grafting integral-- Outlook-- References-- 5 - Concluding remarks-- Learning fluent-- Parsing semantic-- Drawing pragmatic-- 6 - Revealing contributory.
  • (source: Nielsen Book Data)
The progress of today's science and technology encounters an increasing demand for finer and more efficiently performing materials with properties superior over those of current and hence ageing devices. Whether this is concerned with electronics or drug delivery, cancer diagnostics or alternative energy sources, the search for means of miniaturizing the existing materials or devising fundamentally new components with higher capacities appears to be relentless. A saving solution to this is widely proposed as the design and fabrication of nanostructures, molecular architectures with dimensions featured below 100 nm. Replicating Nature's designs faithfully reproduced over millions of years provides perhaps the most straightforward route to success. Nature offers examples of nanodefined self-assemblies in virtually all levels of biological organization. However explicit guidance to the fabrication of functional or specialist nanostructures is of paramount importance. Nanotechnology is often referred to as building nanoscale structures from bottom up. However, while it is visually clear what is at "up" little is given and understood what is at the "bottom". This new book gives the notion of and provides rules for building nanostructures from basics - the very bottom. The main objective of this publication is to bring together contemporary approaches for designing nanostructures that employ naturally derived self-assembling motifs as synthetic platforms. The book has been written to satisfy the demands that motivate the search for and principles that prove to help the design of novel nanostructures. The overall goal is to compile the existing understanding of rules that govern biomolecular self-assembly into a practical guide to molecular nanotechnology. It is written in the shape of a review referenced as fully as permissible within the context of biomolecular design, which forms a general trend throughout. The volume is composed of three core chapters focusing on three prominent topics of applied nanotechnology where the role of nanodesign is predominant. The three key areas from which popular highlights can be drawn are: -employing the genetic repository, DNA, for creating various geometric nanoscale objects and patterns -the empirical pursuit of an artificial virus, a magic bullet in gene therapy -designing artificial extracellular matrices for regenerative medicine Specific applications that arise from designed nanoscale assemblies as well as fabrication and characterization techniques are of secondary importance and whenever they appear serve as progress and innovation highlights. The book takes an unconventional approach in delivering material of this kind. It does not lead straight to applications or methods as most nanotechnology works tend to do, but instead it focuses on the initial and primary aspect of "nano" rather than on "technology". Nanodesign is unique in its own field - illustrations are essential and the cohort of brilliant bioinspired designs reported to date form a major part of the publication. In addition, key bibliographic references are covered as fully as possible. A special appendix giving a short list of leading world laboratories engaged in bioinspired nanodesign is also included.
(source: Nielsen Book Data)
dx.doi.org RSC eBook Collection
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
TP248.25 .N35 R93 2009 Unknown
Book
xv, 594 p. : ill. (some col.) ; 29 cm.
  • List of Contributors. Series Preface. Volume Preface. Part 1: Methods. Calculation of Bonding Properties (Gernot Frenking and Moritz von Hopffgarden). Determining Transition States in Bioinorganic Reactions (Marcus Lundberg and Keiji Morokuma). Quantum Mechanical/Molecular Mechanical (QM/MM) Methods and Applications in Bioinorganic Chemistry (Ulf Ryde). Ab initio and Semiempirical Methods (Serge I. Gorelsky). Spectroscopic Properties of Proten-Bound Cofactors: Calculation by Combined Quantum Mechanical/Molecular Mechanical (QM/MM) Approaches (Mahesh Sundararajan, Christoph Riplinger, Maylis Orio, Frank Wennmohs and Frank Neese). Spectroscopic Properties Obtained from Time-Dependent Density Functional Theory (TD-DFT) (Jochen Autschbach). Nuclear Magnetic Resonance (NMR) Parameters of Transition Metal Complexes: Methods and Applications (Martin Kaupp and Michael Buhl). Calculation of Reduction Potential and pKa. Quantum-Chemistry-Centered Normal Coordinate Analysis (QCC-NCA): Application of NCA for the Simulation of the Vibrational Spectra of Large Molecules (Nicolai Lehnert). Molecular Mechanics in Bioinorganic Chemistry (Robert J. Deeth). Multiconfigurational Quantum Mechanics (QM) for Heavy Element Compounds (Bjorn O. Roos). Approximate Density Functionals: Which Should I Choose? (Dmitrij Rappoport, Nathan R. M. Crawford, Filipp Furche and Kieron Burke). Spin Contamination in Inorganic Chemistry Calculations (Jason L. Sonnerberg, H. Bernhard Schlegel and Hrant P. Hratchian). Gaussian Basis Sets for Quantum Mechanical (QM) Calculations (Kirk A. Peterson). Part 2: Case Studies - Bioinorganic. Modeling Metalloenzymes with Density Functional and Mixed Quantum Mechanical/Molecular Mechanical (QM/MM) Calculations: Progress and Challenges (Richard A. Friesner). Broken Symmetry States of Iron-Sulfur Clusters (Louis Noodleman and David A. Case). Water Oxidation by the Manganese Cluster in Photosynthesis (Per E. M. Siegbahn). Nature of the Catecholate-Fe(III) Bond: High Affinity Binding and Substrate Activation in Bioinorganic Chemistry (Edward I. Solomon, Monita Y. M. Pau and Rosalie K. Hocking). Computational Studies: B12 Cofactors and Their Interaction with Enzyme Active Sites (Thomas C. Brunold). Reaction Coordinate of Pyranopterin Molybdenum Enzymes (Martin L. Kirk, Sushilla Knottenbelt and Abebe Habtegabre). Electronic Structure Calculations: Dinitrogen Reduction in Nitrogenase and Synthetic Model Systems (Felix Tuczek). Hydrogenases: Theoretical Investigations Towards Bioinspired H2 Production and Activation (Maurizio Bruschi, Giuseppe Zampella, Claudio Grego, Luca Bertini, Piercarlo Fantucci and Luca De Gioia). Computational Studies: Cisplatin (Yogita Mantri and Mu-Hyun Baik). Computational Methods: Modeling of Reactivity in Zn-Containing Enzymes (Jon I. Mujika, Adrian J. Mulholland and Jeremy N. Harvey). Combined Density Functional Theory (DFT) and Electrostatics Study of the Proton Pumping Mechanism in Cytochrome c Oxidase (Jason Quenneville, Dragan M. Popovi& and Alexei A. Stuchebrukhov). Computational Studies: Proton/Water Coupling to Metal in Biological Reaction Mechanisms (Y. Bu and R. I. Cukier). Computational Studies: Chemical Evolution of Metal Sites (Kasper P. Jensen). Part 3: Case Studies - Inorganic. Electronic Structure Calculations: Transition Metal-NO Complexes (Abhik Ghosh, Jeanet Conradie and Kathrin H. Hopmann). Structural Origins of Noninnocent Coordination Chemistry (Robert K. Szilagyi). Electronic Structure of Metal-Metal Bonds (John E. McGrady). Computational Methods: Transition Metal Clusters (Regis Gautier, Jean-Francois Halet and Jean-Yves Saillard). Computational Methods: Heteropolyoxoanions (Josep M. Poblet and Xavier Lopez). Electronic Structure Calculations: Metal Carbonyls (Chantal Daniel). Potential Energy Surfaces for Metal-Assisted Chemical Reactions (Tiziana Marino, Maria del Carmen Michelini, Nino Russo, Emilia Sicilia and Marirosa Toscano). Computational Methods: Lanthanides and Actinides (M. Dolg and X. Cao). Spin-Orbit Coupling: Effects in Heavy Element Chemistry (Nikolas Kaltsoyannis). Noble Gas Compounds: Reliable Computational Methods (David A. Dixon). Computational Studies: Boranes (Oottikkal Shameema and Eluvathingal D. Jemmis). Multiple Aromaticity, Multiple Antiaromaticity, and Conflicting Aromaticity in Inorganic Systems (Dmitry Yu. Zubarev and Aledander I. Boldyrev). Theoretical Aspects of Main Group Multiple Bonded Systems (Ioan Silaghi-Dumitrescu, Petronela Petrar, Gabriela Nemes and R. Bruce King). Index.
  • (source: Nielsen Book Data)
A much-needed integration of inorganic chemistry with computational strategies and methods, this resource focuses on applications for inorganic and bioinorganic systems. The coverage helps to understand the spectroscopy and function of enzymes and related compounds, and provides a snapshot of the state-of-the-art in application of computational techniques to (bio)inorganic systems. Expert authors in the area provide practical descriptions of the methods employed and describe case studies in a number of areas of current research in which these methods have made an essential contribution.
(source: Nielsen Book Data)
  • List of Contributors. Series Preface. Volume Preface. Part 1: Methods. Calculation of Bonding Properties (Gernot Frenking and Moritz von Hopffgarden). Determining Transition States in Bioinorganic Reactions (Marcus Lundberg and Keiji Morokuma). Quantum Mechanical/Molecular Mechanical (QM/MM) Methods and Applications in Bioinorganic Chemistry (Ulf Ryde). Ab initio and Semiempirical Methods (Serge I. Gorelsky). Spectroscopic Properties of Proten-Bound Cofactors: Calculation by Combined Quantum Mechanical/Molecular Mechanical (QM/MM) Approaches (Mahesh Sundararajan, Christoph Riplinger, Maylis Orio, Frank Wennmohs and Frank Neese). Spectroscopic Properties Obtained from Time-Dependent Density Functional Theory (TD-DFT) (Jochen Autschbach). Nuclear Magnetic Resonance (NMR) Parameters of Transition Metal Complexes: Methods and Applications (Martin Kaupp and Michael Buhl). Calculation of Reduction Potential and pKa. Quantum-Chemistry-Centered Normal Coordinate Analysis (QCC-NCA): Application of NCA for the Simulation of the Vibrational Spectra of Large Molecules (Nicolai Lehnert). Molecular Mechanics in Bioinorganic Chemistry (Robert J. Deeth). Multiconfigurational Quantum Mechanics (QM) for Heavy Element Compounds (Bjorn O. Roos). Approximate Density Functionals: Which Should I Choose? (Dmitrij Rappoport, Nathan R. M. Crawford, Filipp Furche and Kieron Burke). Spin Contamination in Inorganic Chemistry Calculations (Jason L. Sonnerberg, H. Bernhard Schlegel and Hrant P. Hratchian). Gaussian Basis Sets for Quantum Mechanical (QM) Calculations (Kirk A. Peterson). Part 2: Case Studies - Bioinorganic. Modeling Metalloenzymes with Density Functional and Mixed Quantum Mechanical/Molecular Mechanical (QM/MM) Calculations: Progress and Challenges (Richard A. Friesner). Broken Symmetry States of Iron-Sulfur Clusters (Louis Noodleman and David A. Case). Water Oxidation by the Manganese Cluster in Photosynthesis (Per E. M. Siegbahn). Nature of the Catecholate-Fe(III) Bond: High Affinity Binding and Substrate Activation in Bioinorganic Chemistry (Edward I. Solomon, Monita Y. M. Pau and Rosalie K. Hocking). Computational Studies: B12 Cofactors and Their Interaction with Enzyme Active Sites (Thomas C. Brunold). Reaction Coordinate of Pyranopterin Molybdenum Enzymes (Martin L. Kirk, Sushilla Knottenbelt and Abebe Habtegabre). Electronic Structure Calculations: Dinitrogen Reduction in Nitrogenase and Synthetic Model Systems (Felix Tuczek). Hydrogenases: Theoretical Investigations Towards Bioinspired H2 Production and Activation (Maurizio Bruschi, Giuseppe Zampella, Claudio Grego, Luca Bertini, Piercarlo Fantucci and Luca De Gioia). Computational Studies: Cisplatin (Yogita Mantri and Mu-Hyun Baik). Computational Methods: Modeling of Reactivity in Zn-Containing Enzymes (Jon I. Mujika, Adrian J. Mulholland and Jeremy N. Harvey). Combined Density Functional Theory (DFT) and Electrostatics Study of the Proton Pumping Mechanism in Cytochrome c Oxidase (Jason Quenneville, Dragan M. Popovi& and Alexei A. Stuchebrukhov). Computational Studies: Proton/Water Coupling to Metal in Biological Reaction Mechanisms (Y. Bu and R. I. Cukier). Computational Studies: Chemical Evolution of Metal Sites (Kasper P. Jensen). Part 3: Case Studies - Inorganic. Electronic Structure Calculations: Transition Metal-NO Complexes (Abhik Ghosh, Jeanet Conradie and Kathrin H. Hopmann). Structural Origins of Noninnocent Coordination Chemistry (Robert K. Szilagyi). Electronic Structure of Metal-Metal Bonds (John E. McGrady). Computational Methods: Transition Metal Clusters (Regis Gautier, Jean-Francois Halet and Jean-Yves Saillard). Computational Methods: Heteropolyoxoanions (Josep M. Poblet and Xavier Lopez). Electronic Structure Calculations: Metal Carbonyls (Chantal Daniel). Potential Energy Surfaces for Metal-Assisted Chemical Reactions (Tiziana Marino, Maria del Carmen Michelini, Nino Russo, Emilia Sicilia and Marirosa Toscano). Computational Methods: Lanthanides and Actinides (M. Dolg and X. Cao). Spin-Orbit Coupling: Effects in Heavy Element Chemistry (Nikolas Kaltsoyannis). Noble Gas Compounds: Reliable Computational Methods (David A. Dixon). Computational Studies: Boranes (Oottikkal Shameema and Eluvathingal D. Jemmis). Multiple Aromaticity, Multiple Antiaromaticity, and Conflicting Aromaticity in Inorganic Systems (Dmitry Yu. Zubarev and Aledander I. Boldyrev). Theoretical Aspects of Main Group Multiple Bonded Systems (Ioan Silaghi-Dumitrescu, Petronela Petrar, Gabriela Nemes and R. Bruce King). Index.
  • (source: Nielsen Book Data)
A much-needed integration of inorganic chemistry with computational strategies and methods, this resource focuses on applications for inorganic and bioinorganic systems. The coverage helps to understand the spectroscopy and function of enzymes and related compounds, and provides a snapshot of the state-of-the-art in application of computational techniques to (bio)inorganic systems. Expert authors in the area provide practical descriptions of the methods employed and describe case studies in a number of areas of current research in which these methods have made an essential contribution.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QP517 .Q34 C66 2009 Unknown
Book
ix, 301 p. : ill. (chiefly col.) ; 24 cm.
  • Introduction: What is Biophysical Chemistry? PART 1: BASIC METHODS IN BIOPHYSICAL CHEMISTRY Basic Optical Principles Optical Properties of Biomolecules Basic Fluorescence Techniques Chiroptical and Scattering Methods Magnetic resonance techniques Mass spectrometry PART 2: ADVANCED METHODS IN BIOPHYSICAL CHEMISTRY Fluorescene Microscopy Single-Biomolecule Techniques Ultrafast and Nonlinear Spectroscopy Special Techniques Assay Development, Readers and High-Throughput Screening.
  • (source: Nielsen Book Data)
The only introductory text to address contemporary methods, the really interesting stuff to spice up a standard biophysics course is to be found here. Accessible and didactically written, it is based on a graduate course taught by the author for several years. By presenting a mix of basic theory and real life application examples, he successfully bridges the gap between theory and experiment. Divided into two major parts, this advanced textbook explains all relevant methods used in current industrial research. The first part, basic biophysical chemistry, surveys basic spectroscopic techniques and properties that are the prerequisite for the more sophisticated technologies discussed in the remainder of the book. The second part covers modern, cutting-edge bioanalytical techniques based on physical methods, such as confocal fluorescence, ultrafast spectroscopy, optical tweezers, single molecule electrical measurements, quantum dots, and single molecule force microscopy. Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented.
(source: Nielsen Book Data)
  • Introduction: What is Biophysical Chemistry? PART 1: BASIC METHODS IN BIOPHYSICAL CHEMISTRY Basic Optical Principles Optical Properties of Biomolecules Basic Fluorescence Techniques Chiroptical and Scattering Methods Magnetic resonance techniques Mass spectrometry PART 2: ADVANCED METHODS IN BIOPHYSICAL CHEMISTRY Fluorescene Microscopy Single-Biomolecule Techniques Ultrafast and Nonlinear Spectroscopy Special Techniques Assay Development, Readers and High-Throughput Screening.
  • (source: Nielsen Book Data)
The only introductory text to address contemporary methods, the really interesting stuff to spice up a standard biophysics course is to be found here. Accessible and didactically written, it is based on a graduate course taught by the author for several years. By presenting a mix of basic theory and real life application examples, he successfully bridges the gap between theory and experiment. Divided into two major parts, this advanced textbook explains all relevant methods used in current industrial research. The first part, basic biophysical chemistry, surveys basic spectroscopic techniques and properties that are the prerequisite for the more sophisticated technologies discussed in the remainder of the book. The second part covers modern, cutting-edge bioanalytical techniques based on physical methods, such as confocal fluorescence, ultrafast spectroscopy, optical tweezers, single molecule electrical measurements, quantum dots, and single molecule force microscopy. Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD476.2 .W34 2009 Unknown
Book
xxv, 385 p. : ill. (some col.) ; 24 cm.
  • Introduction. Preface: Beyond the Historical Perspective on Hydrogen and Electron Transfers. Chapter 1: The Transition State Theory Description of Enzyme Catalysis for Classically Activated Reactions: Introduction-- Quantifying the Catalytic Activity of Enzymes-- Free Energy Analysis of Enzyme Catalysis-- Transition State Stabilisation or Ground State Destabilisation?-- Selective Stabilisation of Transition Structures by Enzymes-- Enzyme Flexibility and Dynamics. Chapter 2: Introduction to Quantum Behavior - A Primer: Introduction-- Classical Mechanics-- Quantum Mechanics-- Heisenberg Uncertainty Principle-- The Schrodinger Equation-- Electronic Structure Calculations-- Born-Oppenheimer Approximation-- Hartree-Fock Theory-- Basis sets-- Zero-point Energy-- Density Functional Theory-- DFT Calculations of Free Energies of Activation of Enzyme Models-- DFT Calculations of Kinetic Isotope Effects-- Quantum Mechanics/Molecular Mechanics Methods-- Summary and Outlook. Chapter 3: Quantum Catalysis in Enzymes: Introduction-- Theory-- Variational Transition State Theory-- The Transmission Coefficient-- One-Dimensional Tunneling-- Multidimensional Tunneling-- Ensemble Averaging-- Examples-- Liver Alcohol Dehydrogenase-- Dihydrofolate Reductase-- Soybean-Lipoxygenase-1 and Methylmalonyl-CoA Mutase-- Other Systems and Perspectives-- Concluding Remarks. Chapter 4: Selected Theoretical Models and Computational Methods for Enzymatic Tunneling: Introduction-- Vibronically Nonadiabatic Reactions: Proton-coupled Electron Transfer-- Theory-- Application to Lipoxygenase-- Predominantly Adiabatic Reactions: Proton and Hydride Transfer-- Theory-- Application to Dihydrofolate Reductase-- Emerging Concepts About Enzyme Catalysis. Chapter 5: Kinetic Isotope Effects from Hybrid Classical and Quantum Path Integral Computations: Introduction-- Theoretical Background-- Path Integral Quantum Transition State Theory-- Centroid Path Integral Simulations-- Kinetic Isotope Effects-- Sequential Centroid Path Integral and Umbrella Sampling (PI/UM)-- The PI-FEP/UM Method-- Kleinert's Variational Perturbation (KP) Theory-- Potential Energy Surface-- Combined QM/MM Potentials-- The MOVB Potential-- Computational Details-- Illustrative Examples-- Proton Transfer between Viscosity-- Multiple Reactive Configurations and a Place for Single-Molecule Measurements. Chapter 10. Computational Simulations of Tunnelling Reactions in Enzymes-- Introduction-- Molecular Mechanical Methods-- Quantum Mechanical Methods-- Combined Quantum Mechanical/Molecular Mechanical Methods-- Improving Semiempirical QM Calculations-- Calculation of Potential Energy Surfaces and Free Energy Surfaces-- Simulation of the H-tunnelling Event-- Calculation of H-tunnelling Rates and Kinetic Isotope Effects-- Analysing Molecular Dynamics Trajectories-- A Case Study: Aromatic Amine Dehydrogenase (AADH)-- Preparation of the System-- Analysis of the H-tunnelling Step in AADH-- Analysis of the Role of Promoting Motions in Driving Tunnelling-- Comparison of Short-range Motions in AADH with Long Range Motions in Dihydrofolate Reductase-- Summary. Chapter 11. Tunneling Does Not Contribute Significantly to Enzyme Catalysis, But Studying Temperature Dependence of Isotope Effects is Useful-- Introduction-- Methods-- Simulating Temperature Dependence of KIEs in Enzymes-- Concluding Remarks. Chapter 12: The Use of X-Ray Crystallography to Study Enzymic H-Tunnelling-- Introduction-- X-Ray Crystallography: A Brief Overview-- Accuracy of X-Ray Diffraction Structures-- Dynamic Information from X-Ray Crystallography-- Examples of H-tunnelling Systems Studied by Crystallography-- Crystallographic Studies of AADH Catalytic Mechanism-- Crystallographic Studies of MR-- Conclusions. Chapter 13: The Strengths and Weaknesses of Model Reactions for the Assessment of Tunneling in Enzymic Reactions-- Model Reactions for Biochemical Processes-- Model Reactions Relevant to Enzymic Tunneling-- Isotope Effect Temperature Dependences and the Configurational-Search Framework (CSF) for their Interpretation-- The Traditionally Dependent Category-- The Underdependent Tunneling Category-- The Overdependent Tunneling Category-- Example 1. Hydride Transfer in a Thermophilic Alcohol Dehydrogenase-- The Kirby-Walwyn Intramolecular Model Reaction-- The Powell-Bruice Tunneling Model Reaction-- Enzymic Tunneling in Alcohol Dehydrogenases-- Model Reactions and the Catalytic Power of Alcohol Dehydrogenase-- Example 2. Hydrogen-atom Transfer in Methylmalonyl Coenzyme A Mutase (MCM)-- Non-enzymic Tunneling in the Finke Model Reactions for MCM-- Enzymic Tunneling in MCM-- Model Reactions and MCM Catalytic Power-- The Roles of Theory in the Comparison of Model and Enzymic Reactions-- Model Reactions, Enzymic Accelerations, and Quantum Tunneling. Chapter 14: Long-Distance Electron Tunneling in Proteins: Introduction-- Electronic Coupling and Tunneling Pathways-- Direct Method-- Avoided Crossing-- Application of Koopmans' Theorem-- Generalized Mulliken-Hush Method-- The Propagator Method-- Protein Pruning-- Tunneling Pathways-- The Method of Tunneling Currents-- General Relations-- Many-Electron Picture-- Calculation of Current Density. Hartree-Fock Approximation-- Interatomic Tunneling Currents-- Many-Electron Aspects-- One Tunneling Orbital (OTO) Approximation and Polarization Effects-- The Limitation of the SCF Description of Many-Electron Tunneling-- Correlation Effects. Polarization Cloud Dynamics. Beyond Hartree-Fock Methods-- Quantum Interference Effects. Quantized Vertices-- Electron Transfer or Hole Transfer? Exchange Effects-- Dynamical Aspects.Chapter 15. Proton-coupled Electron Transfer: The Engine that Drives Radical Transport and Catalysis in Biology-- Introduction-- PCET Model Systems-- Unidirectional PCET Networks-- Bidirectional PCET Networks-- PCET Biocatalysis-- PCET in Enzymes: A Study of Ribonucleotide Reductase-- The PCET Pathway in RNR-- PCET in the ?2 Subunit of RNR-- PCET in ?2 Subunit of RNR: PhotoRNRs-- A Model for PCET in RNR-- Concluding Remarks.
  • (source: Nielsen Book Data)
In recent years, there has been an explosion in knowledge and research associated with the field of enzyme catalysis and H-tunneling. Rich in its breath and depth, this introduction to modern theories and methods of study is suitable for experienced researchers those new to the subject. Edited by two leading experts, and bringing together the foremost practitioners in the field, this up-to-date account of a rapidly developing field sits at the interface between biology, chemistry and physics. It covers computational, kinetic and structural analysis of tunnelling and the synergy in combining these methods (with a major focus on H-tunneling reactions in enzyme systems). The book starts with a brief overview of proton and electron transfer history by Nobel Laureate, Rudolph A. Marcus. The reader is then guided through chapters covering almost every aspect of reactions in enzyme catalysis ranging from descriptions of the relevant quantum theory and quantum/classical theoretical methodology to the description of experimental results. The theoretical interpretation of these large systems includes both quantum mechanical and statistical mechanical computations, as well as simple more approximate models. Most of the chapters focus on enzymatic catalysis of hydride, proton and H" transfer, an example of the latter being proton coupled electron transfer. There is also a chapter on electron transfer in proteins. This is timely since the theoretical framework developed fifty years ago for treating electron transfers has now been adapted to H-transfers and electron transfers in proteins. Accessible in style, this book is suitable for a wide audience but will be particularly useful to advanced level undergraduates, postgraduates and early postdoctoral workers.
(source: Nielsen Book Data)
  • Introduction. Preface: Beyond the Historical Perspective on Hydrogen and Electron Transfers. Chapter 1: The Transition State Theory Description of Enzyme Catalysis for Classically Activated Reactions: Introduction-- Quantifying the Catalytic Activity of Enzymes-- Free Energy Analysis of Enzyme Catalysis-- Transition State Stabilisation or Ground State Destabilisation?-- Selective Stabilisation of Transition Structures by Enzymes-- Enzyme Flexibility and Dynamics. Chapter 2: Introduction to Quantum Behavior - A Primer: Introduction-- Classical Mechanics-- Quantum Mechanics-- Heisenberg Uncertainty Principle-- The Schrodinger Equation-- Electronic Structure Calculations-- Born-Oppenheimer Approximation-- Hartree-Fock Theory-- Basis sets-- Zero-point Energy-- Density Functional Theory-- DFT Calculations of Free Energies of Activation of Enzyme Models-- DFT Calculations of Kinetic Isotope Effects-- Quantum Mechanics/Molecular Mechanics Methods-- Summary and Outlook. Chapter 3: Quantum Catalysis in Enzymes: Introduction-- Theory-- Variational Transition State Theory-- The Transmission Coefficient-- One-Dimensional Tunneling-- Multidimensional Tunneling-- Ensemble Averaging-- Examples-- Liver Alcohol Dehydrogenase-- Dihydrofolate Reductase-- Soybean-Lipoxygenase-1 and Methylmalonyl-CoA Mutase-- Other Systems and Perspectives-- Concluding Remarks. Chapter 4: Selected Theoretical Models and Computational Methods for Enzymatic Tunneling: Introduction-- Vibronically Nonadiabatic Reactions: Proton-coupled Electron Transfer-- Theory-- Application to Lipoxygenase-- Predominantly Adiabatic Reactions: Proton and Hydride Transfer-- Theory-- Application to Dihydrofolate Reductase-- Emerging Concepts About Enzyme Catalysis. Chapter 5: Kinetic Isotope Effects from Hybrid Classical and Quantum Path Integral Computations: Introduction-- Theoretical Background-- Path Integral Quantum Transition State Theory-- Centroid Path Integral Simulations-- Kinetic Isotope Effects-- Sequential Centroid Path Integral and Umbrella Sampling (PI/UM)-- The PI-FEP/UM Method-- Kleinert's Variational Perturbation (KP) Theory-- Potential Energy Surface-- Combined QM/MM Potentials-- The MOVB Potential-- Computational Details-- Illustrative Examples-- Proton Transfer between Viscosity-- Multiple Reactive Configurations and a Place for Single-Molecule Measurements. Chapter 10. Computational Simulations of Tunnelling Reactions in Enzymes-- Introduction-- Molecular Mechanical Methods-- Quantum Mechanical Methods-- Combined Quantum Mechanical/Molecular Mechanical Methods-- Improving Semiempirical QM Calculations-- Calculation of Potential Energy Surfaces and Free Energy Surfaces-- Simulation of the H-tunnelling Event-- Calculation of H-tunnelling Rates and Kinetic Isotope Effects-- Analysing Molecular Dynamics Trajectories-- A Case Study: Aromatic Amine Dehydrogenase (AADH)-- Preparation of the System-- Analysis of the H-tunnelling Step in AADH-- Analysis of the Role of Promoting Motions in Driving Tunnelling-- Comparison of Short-range Motions in AADH with Long Range Motions in Dihydrofolate Reductase-- Summary. Chapter 11. Tunneling Does Not Contribute Significantly to Enzyme Catalysis, But Studying Temperature Dependence of Isotope Effects is Useful-- Introduction-- Methods-- Simulating Temperature Dependence of KIEs in Enzymes-- Concluding Remarks. Chapter 12: The Use of X-Ray Crystallography to Study Enzymic H-Tunnelling-- Introduction-- X-Ray Crystallography: A Brief Overview-- Accuracy of X-Ray Diffraction Structures-- Dynamic Information from X-Ray Crystallography-- Examples of H-tunnelling Systems Studied by Crystallography-- Crystallographic Studies of AADH Catalytic Mechanism-- Crystallographic Studies of MR-- Conclusions. Chapter 13: The Strengths and Weaknesses of Model Reactions for the Assessment of Tunneling in Enzymic Reactions-- Model Reactions for Biochemical Processes-- Model Reactions Relevant to Enzymic Tunneling-- Isotope Effect Temperature Dependences and the Configurational-Search Framework (CSF) for their Interpretation-- The Traditionally Dependent Category-- The Underdependent Tunneling Category-- The Overdependent Tunneling Category-- Example 1. Hydride Transfer in a Thermophilic Alcohol Dehydrogenase-- The Kirby-Walwyn Intramolecular Model Reaction-- The Powell-Bruice Tunneling Model Reaction-- Enzymic Tunneling in Alcohol Dehydrogenases-- Model Reactions and the Catalytic Power of Alcohol Dehydrogenase-- Example 2. Hydrogen-atom Transfer in Methylmalonyl Coenzyme A Mutase (MCM)-- Non-enzymic Tunneling in the Finke Model Reactions for MCM-- Enzymic Tunneling in MCM-- Model Reactions and MCM Catalytic Power-- The Roles of Theory in the Comparison of Model and Enzymic Reactions-- Model Reactions, Enzymic Accelerations, and Quantum Tunneling. Chapter 14: Long-Distance Electron Tunneling in Proteins: Introduction-- Electronic Coupling and Tunneling Pathways-- Direct Method-- Avoided Crossing-- Application of Koopmans' Theorem-- Generalized Mulliken-Hush Method-- The Propagator Method-- Protein Pruning-- Tunneling Pathways-- The Method of Tunneling Currents-- General Relations-- Many-Electron Picture-- Calculation of Current Density. Hartree-Fock Approximation-- Interatomic Tunneling Currents-- Many-Electron Aspects-- One Tunneling Orbital (OTO) Approximation and Polarization Effects-- The Limitation of the SCF Description of Many-Electron Tunneling-- Correlation Effects. Polarization Cloud Dynamics. Beyond Hartree-Fock Methods-- Quantum Interference Effects. Quantized Vertices-- Electron Transfer or Hole Transfer? Exchange Effects-- Dynamical Aspects.Chapter 15. Proton-coupled Electron Transfer: The Engine that Drives Radical Transport and Catalysis in Biology-- Introduction-- PCET Model Systems-- Unidirectional PCET Networks-- Bidirectional PCET Networks-- PCET Biocatalysis-- PCET in Enzymes: A Study of Ribonucleotide Reductase-- The PCET Pathway in RNR-- PCET in the ?2 Subunit of RNR-- PCET in ?2 Subunit of RNR: PhotoRNRs-- A Model for PCET in RNR-- Concluding Remarks.
  • (source: Nielsen Book Data)
In recent years, there has been an explosion in knowledge and research associated with the field of enzyme catalysis and H-tunneling. Rich in its breath and depth, this introduction to modern theories and methods of study is suitable for experienced researchers those new to the subject. Edited by two leading experts, and bringing together the foremost practitioners in the field, this up-to-date account of a rapidly developing field sits at the interface between biology, chemistry and physics. It covers computational, kinetic and structural analysis of tunnelling and the synergy in combining these methods (with a major focus on H-tunneling reactions in enzyme systems). The book starts with a brief overview of proton and electron transfer history by Nobel Laureate, Rudolph A. Marcus. The reader is then guided through chapters covering almost every aspect of reactions in enzyme catalysis ranging from descriptions of the relevant quantum theory and quantum/classical theoretical methodology to the description of experimental results. The theoretical interpretation of these large systems includes both quantum mechanical and statistical mechanical computations, as well as simple more approximate models. Most of the chapters focus on enzymatic catalysis of hydride, proton and H" transfer, an example of the latter being proton coupled electron transfer. There is also a chapter on electron transfer in proteins. This is timely since the theoretical framework developed fifty years ago for treating electron transfers has now been adapted to H-transfers and electron transfers in proteins. Accessible in style, this book is suitable for a wide audience but will be particularly useful to advanced level undergraduates, postgraduates and early postdoctoral workers.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QC176.8 .T8 Q37 2009 Unknown
Book
xii, 414 p. : ill. ; 25 cm.
  • 1. LIFE: UNITY OUT OF DIVERSITY-- 2. LIFE: CENTRAL PROPERTIES-- 3. MOLECULAR STRUCTURES BASED ON CARBON: THE FOUNDATION FOR THE MOLECULES OF LIFE-- 4. BUILDING BLOCKS AND GLUE-- 5. FROM METHANE TO CHEMICAL COMMUNICATION-- 6. NITROGEN AND OXYGEN: ATMOSPHERIC ELEMENTS-- 7. MORE ABOUT OXYGEN-CONTAINING MOLECULES-- 8. NOW FOR THE REST OF THE ELEMENTS IN VITAMIN PILLS-- 9. PROTEINS: AN AMAZING COLLECTION OF MULTIFUNCTIONAL MOLECULES-- 10. AMINO ACIDS: THE BUILDING BLOCKS OF PROTEINS-- 11. PROTEINS ARE THREE-DIMENSIONAL OBJECTS-- 12. NUCLEOTIDES ARE THE BUILDING BLOCKS OF NUCLEIC ACIDS: THE STUFF OF GENES-- 13. THE CENTRAL DOGMA OF BIOLOGY AND PROTEIN SYNTHESIS-- 14. GENOMES-- 15. VITAMINS: MOLECULES OF LIFE-- 16. CARBOHYDRATES: SWEETNESS AND LIFE-- 17. GENERATING ENERGY FROM CATABOLISM-- 18. FATTY ACIDS: THE BUILDING BLOCKS OF LIPIDS-- 19. LIPIDS: THE GREASY STUFF OF LIFE-- 20. STEROIDS: SEX AND OTHER GOOD THINGS-- 21. YOUR BRAIN: WHAT IT DOES AND HOW IT WORKS-- 22. YOUR BRAIN: GOOD THINGS AND NOT-GOOD THINGS-- 23. ANTIBIOTICS: THE NEVER-ENDING WAR AGAINST INFECTIOUS DISEASE-- 24. CANCER: WHAT IT IS AND WHAT WE CAN DO ABOUT IT-- 25. CHEMICAL COMMUNICATION.
  • (source: Nielsen Book Data)
Written with the non-scientist in mind, this book employs the molecule and its interactions to explain the characteristics of living organisms in terms of the underlying chemistry of life. Following introductory chapters on the fundamentals of life, attention then turns to small molecules such as hormones and neurotransmitters and subsequently to macromolecules including proteins and nucleic acids. The interactions between small and macromolecules remains a central point throughout the book. These include enzymatic catalysis, hormone action, neurotransmission, regulation of metabolism, biosynthesis of macromolecules, the mechanism of action of drugs, taste, olfaction, learning and memory, and chemical communication. A second central point of emphasis is the sensitive relationship between chemical structure and biological activity. Examples abound and include why subtle changes in fatty acid architecture have positive or negative outcomes for human health in omega-three fatty acids and trans fats and how modest changes in the chemical decoration of the steroid skeleton provide the difference between male and female sex hormones. Beyond these examples taken from the chemistry of small molecules, the book includes a thoughtful consideration of genomics, including the relationship between genome structure and species. The theme of human health appears throughout the book. Cardiovascular medicine, cancer, metabolic diseases, and diseases of the nervous system receive significant attention including consideration of how a variety of drugs work in combating these issues. In sum, the goal of this book is to inform the non-scientist community in a way that will lead to increased understanding of the relationship between chemistry and life.
(source: Nielsen Book Data)
  • 1. LIFE: UNITY OUT OF DIVERSITY-- 2. LIFE: CENTRAL PROPERTIES-- 3. MOLECULAR STRUCTURES BASED ON CARBON: THE FOUNDATION FOR THE MOLECULES OF LIFE-- 4. BUILDING BLOCKS AND GLUE-- 5. FROM METHANE TO CHEMICAL COMMUNICATION-- 6. NITROGEN AND OXYGEN: ATMOSPHERIC ELEMENTS-- 7. MORE ABOUT OXYGEN-CONTAINING MOLECULES-- 8. NOW FOR THE REST OF THE ELEMENTS IN VITAMIN PILLS-- 9. PROTEINS: AN AMAZING COLLECTION OF MULTIFUNCTIONAL MOLECULES-- 10. AMINO ACIDS: THE BUILDING BLOCKS OF PROTEINS-- 11. PROTEINS ARE THREE-DIMENSIONAL OBJECTS-- 12. NUCLEOTIDES ARE THE BUILDING BLOCKS OF NUCLEIC ACIDS: THE STUFF OF GENES-- 13. THE CENTRAL DOGMA OF BIOLOGY AND PROTEIN SYNTHESIS-- 14. GENOMES-- 15. VITAMINS: MOLECULES OF LIFE-- 16. CARBOHYDRATES: SWEETNESS AND LIFE-- 17. GENERATING ENERGY FROM CATABOLISM-- 18. FATTY ACIDS: THE BUILDING BLOCKS OF LIPIDS-- 19. LIPIDS: THE GREASY STUFF OF LIFE-- 20. STEROIDS: SEX AND OTHER GOOD THINGS-- 21. YOUR BRAIN: WHAT IT DOES AND HOW IT WORKS-- 22. YOUR BRAIN: GOOD THINGS AND NOT-GOOD THINGS-- 23. ANTIBIOTICS: THE NEVER-ENDING WAR AGAINST INFECTIOUS DISEASE-- 24. CANCER: WHAT IT IS AND WHAT WE CAN DO ABOUT IT-- 25. CHEMICAL COMMUNICATION.
  • (source: Nielsen Book Data)
Written with the non-scientist in mind, this book employs the molecule and its interactions to explain the characteristics of living organisms in terms of the underlying chemistry of life. Following introductory chapters on the fundamentals of life, attention then turns to small molecules such as hormones and neurotransmitters and subsequently to macromolecules including proteins and nucleic acids. The interactions between small and macromolecules remains a central point throughout the book. These include enzymatic catalysis, hormone action, neurotransmission, regulation of metabolism, biosynthesis of macromolecules, the mechanism of action of drugs, taste, olfaction, learning and memory, and chemical communication. A second central point of emphasis is the sensitive relationship between chemical structure and biological activity. Examples abound and include why subtle changes in fatty acid architecture have positive or negative outcomes for human health in omega-three fatty acids and trans fats and how modest changes in the chemical decoration of the steroid skeleton provide the difference between male and female sex hormones. Beyond these examples taken from the chemistry of small molecules, the book includes a thoughtful consideration of genomics, including the relationship between genome structure and species. The theme of human health appears throughout the book. Cardiovascular medicine, cancer, metabolic diseases, and diseases of the nervous system receive significant attention including consideration of how a variety of drugs work in combating these issues. In sum, the goal of this book is to inform the non-scientist community in a way that will lead to increased understanding of the relationship between chemistry and life.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD415 .C66 2009 Unknown
Book
4 v. : ill. (some col.) ; 29 cm.
This is the first major reference at the interface of chemistry, biology, and medicine. Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: applications of chemical biology; biomolecules within the cell; chemical views of biology; chemistry of biological processes and systems; synthetic molecules as tools for chemical biology; technologies and techniques in chemical biology; and, some 300 articles that range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the "Wiley Encyclopedia of Chemical Biology" builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.
(source: Nielsen Book Data)
This is the first major reference at the interface of chemistry, biology, and medicine. Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: applications of chemical biology; biomolecules within the cell; chemical views of biology; chemistry of biological processes and systems; synthetic molecules as tools for chemical biology; technologies and techniques in chemical biology; and, some 300 articles that range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the "Wiley Encyclopedia of Chemical Biology" builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Reference (non-circulating)
QP512 .W48 2009 V.1 In-library use
QP512 .W48 2009 V.2 In-library use
QP512 .W48 2009 V.3 In-library use
QP512 .W48 2009 V.4 In-library use
Book
xvi, 492 p. : col. ill. ; 26 cm.
  • Preface.1. Basic Thermodynamic and Biochemical Concepts.Part 1: Thermodynamics and Kinetics:.2. First Law of Thermodynamics.3. Second Law of Thermodynamics.4. Phase Diagrams, Mixtures, and Chemical Potential.5. Equilibria and Reactions Involving Protons.6. Oxidation/Reduction Reactions and Bioenergetics.7. Kinetics and Enzymes.8. The Boltzmann Distribution and Statistical Thermodynamics.Part 2: Quantum Mechanics and Spectroscopy:.9. Quantum Theory: Introduction and Principles.10. Particle in a Box and Tunneling.11. Vibrational Motion and Infrared Spectroscopy.12. Atomic Structure: Hydrogen Atom and Multi-Electron Atoms.13. Chemical Bonds and Protein Interactions.14. Electronic Transitions and Optical Spectroscopy.15. X-Ray Diffraction and Extended X-Ray Absorption Fine Structure.16. Magnetic Resonance.Part 3: Understanding Biological Systems using Physical Chemistry:.17. Signal Transduction.18. Membrane Potentials, Transporters, and Channels.19. Molecular Imaging.20. Photosynthesis.References and Further Reading.Problems.Answers to Problems.Index.
  • (source: Nielsen Book Data)
'"Biophysical Chemistry" is an outstanding book that delivers both fundamental and complex biophysical principles, along with an excellent overview of the current biophysical research areas, in a manner that makes it accessible for mathematically and non-mathematically inclined readers' - ("Journal of Chemical Biology", February 2009). This text presents physical chemistry through the use of biological and biochemical topics, examples and applications to biochemistry. It lays out the necessary calculus in a step by step fashion for students who are less mathematically inclined, leading them through fundamental concepts, such as a quantum mechanical description of the hydrogen atom rather than simply stating outcomes. The techniques are presented with an emphasis on learning by analyzing real data. It features qualitative and quantitative problems at the end of each chapter. All art are available for download online and on CD-ROM.
(source: Nielsen Book Data)
  • Preface.1. Basic Thermodynamic and Biochemical Concepts.Part 1: Thermodynamics and Kinetics:.2. First Law of Thermodynamics.3. Second Law of Thermodynamics.4. Phase Diagrams, Mixtures, and Chemical Potential.5. Equilibria and Reactions Involving Protons.6. Oxidation/Reduction Reactions and Bioenergetics.7. Kinetics and Enzymes.8. The Boltzmann Distribution and Statistical Thermodynamics.Part 2: Quantum Mechanics and Spectroscopy:.9. Quantum Theory: Introduction and Principles.10. Particle in a Box and Tunneling.11. Vibrational Motion and Infrared Spectroscopy.12. Atomic Structure: Hydrogen Atom and Multi-Electron Atoms.13. Chemical Bonds and Protein Interactions.14. Electronic Transitions and Optical Spectroscopy.15. X-Ray Diffraction and Extended X-Ray Absorption Fine Structure.16. Magnetic Resonance.Part 3: Understanding Biological Systems using Physical Chemistry:.17. Signal Transduction.18. Membrane Potentials, Transporters, and Channels.19. Molecular Imaging.20. Photosynthesis.References and Further Reading.Problems.Answers to Problems.Index.
  • (source: Nielsen Book Data)
'"Biophysical Chemistry" is an outstanding book that delivers both fundamental and complex biophysical principles, along with an excellent overview of the current biophysical research areas, in a manner that makes it accessible for mathematically and non-mathematically inclined readers' - ("Journal of Chemical Biology", February 2009). This text presents physical chemistry through the use of biological and biochemical topics, examples and applications to biochemistry. It lays out the necessary calculus in a step by step fashion for students who are less mathematically inclined, leading them through fundamental concepts, such as a quantum mechanical description of the hydrogen atom rather than simply stating outcomes. The techniques are presented with an emphasis on learning by analyzing real data. It features qualitative and quantitative problems at the end of each chapter. All art are available for download online and on CD-ROM.
(source: Nielsen Book Data)
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
QD476.2 .A44 2008 Unknown

Looking for different results?

Modify your search: Remove limit(s) Search all fields

Search elsewhere: Search WorldCat Search library website