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Book
1 online resource. Digital: text file; PDF.
  • Biomedical Signal Processing
  • Biomedical Imaging and Image Processing
  • Biosensors and Bioinstrumentation
  • Bio-micro/nano Technologies
  • Biomaterials
  • Biomechanics, Robotics and Minimally Invasive Surgery
  • Cardiovascular, Respiratory and Endocrine Systems Engineering
  • Neural and Rehabilitation Engineering
  • Molecular, Cellular and Tissue Engineering
  • Bioinformatics and Computational Biology
  • Clinical Engineering and Health Technology Assessment
  • Health Informatics, E-health and Telemedicine
  • Biomedical Engineering Education
  • Biomimetic Organ-on-Chip Systems
  • Nanotechnology and Pulsed Electric Fields
  • Advanced techniques for treating deep seated tumor using Electrochemotherapy (ECT) and Irreversible Electroporation (IRE). Bioimpedance
  • Workshop: Radiological Equipment Maintenance Issues
  • Real-time neuroimaging of the human brain: Methods and applications
  • Certification of clinical biomedical engineers: national and international perspectives
  • AHP in healthcare decision making and user need elicitation
  • Education BME-ENA
  • Disaster Preparedness Program for Health Facility?s Technology Managers.
This volume presents the Proceedings of the 6th European Conference of the International Federation for Medical and Biological Engineering (MBEC2014), held in Dubrovnik September 7? 11, 2014. The general theme of MBEC 2014 is "Towards new horizons in biomedical engineering" The scientific discussions in these conference proceedings include the following themes: - Biomedical Signal Processing - Biomedical Imaging and Image Processing - Biosensors and Bioinstrumentation - Bio-Micro/Nano Technologies - Biomaterials - Biomechanics, Robotics and Minimally Invasive Surgery - Cardiovascular, Respiratory and Endocrine Systems Engineering - Neural and Rehabilitation Engineering - Molecular, Cellular and Tissue Engineering - Bioinformatics and Computational Biology - Clinical Engineering and Health Technology Assessment - Health Informatics, E-Health and Telemedicine - Biomedical Engineering Education.
  • Biomedical Signal Processing
  • Biomedical Imaging and Image Processing
  • Biosensors and Bioinstrumentation
  • Bio-micro/nano Technologies
  • Biomaterials
  • Biomechanics, Robotics and Minimally Invasive Surgery
  • Cardiovascular, Respiratory and Endocrine Systems Engineering
  • Neural and Rehabilitation Engineering
  • Molecular, Cellular and Tissue Engineering
  • Bioinformatics and Computational Biology
  • Clinical Engineering and Health Technology Assessment
  • Health Informatics, E-health and Telemedicine
  • Biomedical Engineering Education
  • Biomimetic Organ-on-Chip Systems
  • Nanotechnology and Pulsed Electric Fields
  • Advanced techniques for treating deep seated tumor using Electrochemotherapy (ECT) and Irreversible Electroporation (IRE). Bioimpedance
  • Workshop: Radiological Equipment Maintenance Issues
  • Real-time neuroimaging of the human brain: Methods and applications
  • Certification of clinical biomedical engineers: national and international perspectives
  • AHP in healthcare decision making and user need elicitation
  • Education BME-ENA
  • Disaster Preparedness Program for Health Facility?s Technology Managers.
This volume presents the Proceedings of the 6th European Conference of the International Federation for Medical and Biological Engineering (MBEC2014), held in Dubrovnik September 7? 11, 2014. The general theme of MBEC 2014 is "Towards new horizons in biomedical engineering" The scientific discussions in these conference proceedings include the following themes: - Biomedical Signal Processing - Biomedical Imaging and Image Processing - Biosensors and Bioinstrumentation - Bio-Micro/Nano Technologies - Biomaterials - Biomechanics, Robotics and Minimally Invasive Surgery - Cardiovascular, Respiratory and Endocrine Systems Engineering - Neural and Rehabilitation Engineering - Molecular, Cellular and Tissue Engineering - Bioinformatics and Computational Biology - Clinical Engineering and Health Technology Assessment - Health Informatics, E-Health and Telemedicine - Biomedical Engineering Education.
Book
1 online resource. Digital: text file; PDF.
  • Peroxynitrite induces degradation of myosin heavy chain via p38 MAPK and muscle-specific E3 ubiquitin ligases in C2 skeletal myotubes
  • Alterations in the coagulation system of active smokers from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study
  • C-reactive protein and lipoprotein-associated phospholipase A2 in smokers and nonsmokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study
  • Green tea drinking improves erythrocytes and saliva oxidative status in the elderly
  • Cardiovascular effects of N-acetylcysteine in meconium-induced acute lung injury
  • Alterations in vagal-immune pathway in long-lasting mental stress
  • Nocturnal parasympathetic modulation of heart rate in obesity-hypoventilation patients
  • N-acetylcysteine Alleviates the Meconium-Induced Acute Lung Injury.
Cardiorespiratory function is prominently affected by oxidative stress. Cigarette smoking is the archetype of oxidative and nitrative stress and free radical formation. New adverse effects of smoking keep on propping up in research. The chapters provide the comprehensive view of new developments in this area regarding cardiovascular and lung function and muscle catabolism. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented. Much less is known about the effect of cognitive stress on vagally-mediated cardiorespiratory function and surprisingly, on vagal immune pathway. The experimental studies also show that clinically important meconium aspiration syndrome contains an oxidative trait which is amenable to antioxidative treatment. This volume creates a source of information on the damaging role of oxidative stress in cardiorespiratory function that has by far not been available.
  • Peroxynitrite induces degradation of myosin heavy chain via p38 MAPK and muscle-specific E3 ubiquitin ligases in C2 skeletal myotubes
  • Alterations in the coagulation system of active smokers from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study
  • C-reactive protein and lipoprotein-associated phospholipase A2 in smokers and nonsmokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study
  • Green tea drinking improves erythrocytes and saliva oxidative status in the elderly
  • Cardiovascular effects of N-acetylcysteine in meconium-induced acute lung injury
  • Alterations in vagal-immune pathway in long-lasting mental stress
  • Nocturnal parasympathetic modulation of heart rate in obesity-hypoventilation patients
  • N-acetylcysteine Alleviates the Meconium-Induced Acute Lung Injury.
Cardiorespiratory function is prominently affected by oxidative stress. Cigarette smoking is the archetype of oxidative and nitrative stress and free radical formation. New adverse effects of smoking keep on propping up in research. The chapters provide the comprehensive view of new developments in this area regarding cardiovascular and lung function and muscle catabolism. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented. Much less is known about the effect of cognitive stress on vagally-mediated cardiorespiratory function and surprisingly, on vagal immune pathway. The experimental studies also show that clinically important meconium aspiration syndrome contains an oxidative trait which is amenable to antioxidative treatment. This volume creates a source of information on the damaging role of oxidative stress in cardiorespiratory function that has by far not been available.
Book
1 online resource : ill.
  • Part I: Childhood
  • 1.Cognitive abilities in childhood and adolescence.-2.Interactions between socioeconomic status and components of variation in cognitive ability.-3.Genetic and environmental influences on intellectual disability in childhood
  • Part II: Adulthood
  • 4.Cognition in middle adulthood.-5.Normative cognitive aging
  • 6.Gene by environment interplay in cognitive aging
  • 7.Dementia: Genes, environments, interactions
  • Part III: Biology and Neurobiology
  • 8.Brain imaging and cognition
  • 9.Animal models of general cognitive ability for genetic research into cognitive functioning
  • Part IV: Conclusion.-10.Future directions.-.
  • Part I: Childhood
  • 1.Cognitive abilities in childhood and adolescence.-2.Interactions between socioeconomic status and components of variation in cognitive ability.-3.Genetic and environmental influences on intellectual disability in childhood
  • Part II: Adulthood
  • 4.Cognition in middle adulthood.-5.Normative cognitive aging
  • 6.Gene by environment interplay in cognitive aging
  • 7.Dementia: Genes, environments, interactions
  • Part III: Biology and Neurobiology
  • 8.Brain imaging and cognition
  • 9.Animal models of general cognitive ability for genetic research into cognitive functioning
  • Part IV: Conclusion.-10.Future directions.-.
Book
1 online resource (295 pages)
Calculus of Thought: Neuromorphic Logistic Regression in Cognitive Machines is a must-read for all scientists about a very simple computation method designed to simulate big-data neural processing. This book is inspired by the Calculus Ratiocinator idea of Gottfried Leibniz, which is that machine computation should be developed to simulate human cognitive processes, thus avoiding problematic subjective bias in analytic solutions to practical and scientific problems. The reduced error logistic regression (RELR) method is proposed as such a "Calculus of Thought." This book reviews how RELR's completely automated processing may parallel important aspects of explicit and implicit learning in neural processes. It emphasizes the fact that RELR is really just a simple adjustment to already widely used logistic regression, along with RELR's new applications that go well beyond standard logistic regression in prediction and explanation. Readers will learn how RELR solves some of the most basic problems in today's big and small data related to high dimensionality, multi-colinearity, and cognitive bias in capricious outcomes commonly involving human behavior. Features include: provides a high-level introduction and detailed reviews of the neural, statistical and machine learning knowledge base as a foundation for a new era of smarter machines; argues that smarter machine learning to handle both explanation and prediction without cognitive bias must have a foundation in cognitive neuroscience and must embody similar explicit and implicit learning principles that occur in the brain; and offers a new neuromorphic foundation for machine learning based upon the reduced error logistic regression (RELR) method and provides simple examples of RELR computations in toy problems that can be accessed in spreadsheet workbooks through a companion website.
(source: Nielsen Book Data)
Calculus of Thought: Neuromorphic Logistic Regression in Cognitive Machines is a must-read for all scientists about a very simple computation method designed to simulate big-data neural processing. This book is inspired by the Calculus Ratiocinator idea of Gottfried Leibniz, which is that machine computation should be developed to simulate human cognitive processes, thus avoiding problematic subjective bias in analytic solutions to practical and scientific problems. The reduced error logistic regression (RELR) method is proposed as such a "Calculus of Thought." This book reviews how RELR's completely automated processing may parallel important aspects of explicit and implicit learning in neural processes. It emphasizes the fact that RELR is really just a simple adjustment to already widely used logistic regression, along with RELR's new applications that go well beyond standard logistic regression in prediction and explanation. Readers will learn how RELR solves some of the most basic problems in today's big and small data related to high dimensionality, multi-colinearity, and cognitive bias in capricious outcomes commonly involving human behavior. Features include: provides a high-level introduction and detailed reviews of the neural, statistical and machine learning knowledge base as a foundation for a new era of smarter machines; argues that smarter machine learning to handle both explanation and prediction without cognitive bias must have a foundation in cognitive neuroscience and must embody similar explicit and implicit learning principles that occur in the brain; and offers a new neuromorphic foundation for machine learning based upon the reduced error logistic regression (RELR) method and provides simple examples of RELR computations in toy problems that can be accessed in spreadsheet workbooks through a companion website.
(source: Nielsen Book Data)
Book
1 online resource (xiii, 585 pages) : illustrations (some color)
  • Section 1: Neurohistological techniques
  • 1. Brain tissue preparation, sectioning and staining
  • 2. Brain stereotactic injections
  • 3. Tract tracing at light and electron microscopy
  • 4. Stereological analysis of neurological tissues
  • Section 2: In vitro preparations
  • 5. Preparation and use of rodent hippocampal brain slices
  • 6.? Single-Cell Neuronal Dissociation For Electrophysiological Studies
  • 7. Isolation and Culture of Human Neurons, Microglia and Astrocytes
  • 8. Isolation and Culture of Neural Stem/progenitor Cells
  • 9. Isolation of mitochondria from brain tissue and cells
  • 10. Isolation of synaptosomes from archived brain tissues
  • 11. Xenopus oocytes isolation and microinjection
  • Section 3: Leukocyte isolation and application in neuroscience
  • 12. Centrifugal elutriation for studies of neuroimmunity
  • 13. Flow cytometry in neuroscience research
  • Section 4: Standard Laboratory Nucleic Acid and Protein Detections
  • 14. Western Blotting Technique in Biomedical Research
  • 15. Polymerase chain reaction (PCR) and Real-time RT PCR
  • Section 5: Nanomedicine
  • 16. Nanoformulations
  • 17. Neuronanomedicine
  • Section 6: Bioimaging
  • 18. Confocal imaging of nerve cells
  • 19. Magnetic resonance imaging (MRI)
  • 20. X-Ray, Positron Emission, and Single Photon Emission Tomographic Bioimaging
  • 21. Non-Invasive Neurophysiological Imaging with Magnetoencephalography
  • 22. Multiphoton Brain Imaging
  • Section 7: Neuroelectrophysiology
  • 23. Techniques for Extracellular Recordings
  • 24. Blind patch-clamp recordings from rodent hippocampal slices
  • 25. Whole-cell patch clamp recordings
  • Section 8: Immunohistochemistry and autoradiography
  • 26. Analysis of Receptor Binding And Quantitative Autoradiography
  • 27. Techniques in Immunohistochemistry and immunocytochemistry
  • Section 9: Analysis of Gene Expression
  • 28. Protein identification by mass spectrometry: Proteomics
  • 29. DNA Microarrays as a Tool for Neurosciences Research
  • 30. Metabolomics
  • 31. Bioinformatic Methods and Resources for Neuroscience Research
  • Section 10: Animal Models: Behavior and Pathology
  • 32. Motor function in rodent models of neurodegenerative disorders
  • 33. Humanized mice
  • 34. Animal models for PD and ALS
  • 35. Animal models for Alzheimer's Disease
  • 36. Animal Models: Behavior and Pathology.
Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a blueprint for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
  • Section 1: Neurohistological techniques
  • 1. Brain tissue preparation, sectioning and staining
  • 2. Brain stereotactic injections
  • 3. Tract tracing at light and electron microscopy
  • 4. Stereological analysis of neurological tissues
  • Section 2: In vitro preparations
  • 5. Preparation and use of rodent hippocampal brain slices
  • 6.? Single-Cell Neuronal Dissociation For Electrophysiological Studies
  • 7. Isolation and Culture of Human Neurons, Microglia and Astrocytes
  • 8. Isolation and Culture of Neural Stem/progenitor Cells
  • 9. Isolation of mitochondria from brain tissue and cells
  • 10. Isolation of synaptosomes from archived brain tissues
  • 11. Xenopus oocytes isolation and microinjection
  • Section 3: Leukocyte isolation and application in neuroscience
  • 12. Centrifugal elutriation for studies of neuroimmunity
  • 13. Flow cytometry in neuroscience research
  • Section 4: Standard Laboratory Nucleic Acid and Protein Detections
  • 14. Western Blotting Technique in Biomedical Research
  • 15. Polymerase chain reaction (PCR) and Real-time RT PCR
  • Section 5: Nanomedicine
  • 16. Nanoformulations
  • 17. Neuronanomedicine
  • Section 6: Bioimaging
  • 18. Confocal imaging of nerve cells
  • 19. Magnetic resonance imaging (MRI)
  • 20. X-Ray, Positron Emission, and Single Photon Emission Tomographic Bioimaging
  • 21. Non-Invasive Neurophysiological Imaging with Magnetoencephalography
  • 22. Multiphoton Brain Imaging
  • Section 7: Neuroelectrophysiology
  • 23. Techniques for Extracellular Recordings
  • 24. Blind patch-clamp recordings from rodent hippocampal slices
  • 25. Whole-cell patch clamp recordings
  • Section 8: Immunohistochemistry and autoradiography
  • 26. Analysis of Receptor Binding And Quantitative Autoradiography
  • 27. Techniques in Immunohistochemistry and immunocytochemistry
  • Section 9: Analysis of Gene Expression
  • 28. Protein identification by mass spectrometry: Proteomics
  • 29. DNA Microarrays as a Tool for Neurosciences Research
  • 30. Metabolomics
  • 31. Bioinformatic Methods and Resources for Neuroscience Research
  • Section 10: Animal Models: Behavior and Pathology
  • 32. Motor function in rodent models of neurodegenerative disorders
  • 33. Humanized mice
  • 34. Animal models for PD and ALS
  • 35. Animal models for Alzheimer's Disease
  • 36. Animal Models: Behavior and Pathology.
Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a blueprint for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
Book
online resource (xiii, 585 pages) : illustrations (some color) ; 26 cm
  • Part I. Neurohistological Techniques
  • Brain Tissue Preparation, Sectioning, and Staining / Jingdong Zhang and Huangui Xiong
  • Brain Stereotaxic Injection / Jingdong Zhang and Huangui Xiong
  • Neuronal Tract Tracing with Light and Electron Microscopy / Jingdong Zhang and Huangui Xiong
  • Stereological Analysis / Kristi M. Anderson, Adam M. Szlachetka and R. Lee Mosley
  • Part II. In Vitro Preparations
  • Preparation and Use of Rodent Hippocampal Slices / Huangui Xiong and Jianxun Xia
  • Single-Cell Neuronal Dissociation for Electrophysiological Studies / Yu-Long Li
  • Isolation and Culture of Human Neurons, Microglia, and Astrocytes / Li Wu and Santhi Gorantla
  • Isolation and Culture of Neural Stem/Progenitor Cells / Hui Peng, Qiang Chen and Jialin Zheng
  • Isolation of Mitochondria from Brain Tissue and Cells / Changhai Tian and Jialin Zheng
  • Isolation of Synaptosomes from Archived Brain Tissues / Gurudutt Pendyala, James L. Buescher and Howard S. Fox
  • Xenopus Oocytes Isolation and Microinjection / Huangui Xiong
  • Part III. Leukocyte Isolation and Application in Neuroscience
  • Centrifugal Elutriation for Studies of Neuroimmunity / Santhi Gorantla, Myhanh Che and Howard E. Gendelman
  • Flow Cytometry in Neuroscience Research / Charles Kuszynski
  • Part IV. Standard Laboratory Nucleic Acid and Protein Detections
  • Western Blotting Technique in Biomedical Research / Jianuo Liu, James Haorah and Huangui Xiong
  • Polymerase Chain Reaction (PCR) and Real-Time PCR / Georgette D. Kanmogne
  • Part V. Nanomedicine
  • Nanoformulations / Xin-Ming Liu and Tatiana K. Bronich
  • Neuronanomedicine / JoEllyn M. McMillan, Xin-Ming Liu and Howard E. Gendelman
  • Part VI. Bioimaging
  • Confocal Imaging of Nerve Cells / You Zhou
  • Magnetic Resonance Imaging / Yutong Liu
  • X-Ray, Positron Emission, and Single Photon Emission Tomographic Bioimaging / Katherine A. Estes, Jacob C. Peterson, Adam M. Szlachetka and R. Lee Mosley
  • Noninvasive Neurophysiological Imaging with Magnetoencephalography / Tony W. Wilson
  • Multiphoton Brain Imaging / Anna Dunaevsky
  • Part VII. Neuroelectrophysiology
  • Techniques for Extracellular Recordings / Jingdong Zhang, Jianxun Xia and Huangui Xiong
  • Blind Patch-Clamp Recordings from Rodent Hippocampal Slices / Jianxun Xia and Huangui Xiong
  • Whole-Cell Patch-Clamp Recording / Matthew J. Van Hook and Wallace B. Thoreson
  • Part VIII. Immunohistochemistry and Autoradiography
  • Analysis of Receptor Binding and Quantitative Autoradiography / L. Charles Murrin
  • Techniques in Immunohistochemistry and Immunocytochemistry / Yang Yuan and Jyothi Arikkath
  • Part IX. Analysis of Gene Expression
  • Protein Identification by Mass Spectrometry: Proteomics / Melinda Wojtkiewicz, Kelley Barnett and Pawel Ciborowski
  • DNA Microarrays as a Tool for Neurosciences Research / James D. Eudy, Lynette Smith
  • Metabolomics / Yazen Alnouti
  • Bioinformatic Methods and Resources for Neuroscience Research / Chittibabu Guda
  • Part X. Animal Models: Behavior and Pathology
  • Motor Function in Rodent Models of Neurodegenerative Disorders / Jessica A. Hutter Saunders, Max V. Kuenstling, Robert A. Weir, R. Lee Mosley and Howard E. Gendelman
  • Humanized Mice / Larisa Y. Poluektova and Edward Makarov
  • Animal Models for PD and ALS / Max V. Kuenstling, Adam M. Szlachetka and R. Lee Mosley
  • Animal Models of Alzheimer's Disease / Tomomi Kiyota
  • Animal Models: Behavior and Pathology: Preclinical Assessment of the Putative Cognitive Deficits in HAND / Landhing M. Moran, Rosemarie M. Booze and Charles F. Mactutus.
Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a blueprint for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
  • Part I. Neurohistological Techniques
  • Brain Tissue Preparation, Sectioning, and Staining / Jingdong Zhang and Huangui Xiong
  • Brain Stereotaxic Injection / Jingdong Zhang and Huangui Xiong
  • Neuronal Tract Tracing with Light and Electron Microscopy / Jingdong Zhang and Huangui Xiong
  • Stereological Analysis / Kristi M. Anderson, Adam M. Szlachetka and R. Lee Mosley
  • Part II. In Vitro Preparations
  • Preparation and Use of Rodent Hippocampal Slices / Huangui Xiong and Jianxun Xia
  • Single-Cell Neuronal Dissociation for Electrophysiological Studies / Yu-Long Li
  • Isolation and Culture of Human Neurons, Microglia, and Astrocytes / Li Wu and Santhi Gorantla
  • Isolation and Culture of Neural Stem/Progenitor Cells / Hui Peng, Qiang Chen and Jialin Zheng
  • Isolation of Mitochondria from Brain Tissue and Cells / Changhai Tian and Jialin Zheng
  • Isolation of Synaptosomes from Archived Brain Tissues / Gurudutt Pendyala, James L. Buescher and Howard S. Fox
  • Xenopus Oocytes Isolation and Microinjection / Huangui Xiong
  • Part III. Leukocyte Isolation and Application in Neuroscience
  • Centrifugal Elutriation for Studies of Neuroimmunity / Santhi Gorantla, Myhanh Che and Howard E. Gendelman
  • Flow Cytometry in Neuroscience Research / Charles Kuszynski
  • Part IV. Standard Laboratory Nucleic Acid and Protein Detections
  • Western Blotting Technique in Biomedical Research / Jianuo Liu, James Haorah and Huangui Xiong
  • Polymerase Chain Reaction (PCR) and Real-Time PCR / Georgette D. Kanmogne
  • Part V. Nanomedicine
  • Nanoformulations / Xin-Ming Liu and Tatiana K. Bronich
  • Neuronanomedicine / JoEllyn M. McMillan, Xin-Ming Liu and Howard E. Gendelman
  • Part VI. Bioimaging
  • Confocal Imaging of Nerve Cells / You Zhou
  • Magnetic Resonance Imaging / Yutong Liu
  • X-Ray, Positron Emission, and Single Photon Emission Tomographic Bioimaging / Katherine A. Estes, Jacob C. Peterson, Adam M. Szlachetka and R. Lee Mosley
  • Noninvasive Neurophysiological Imaging with Magnetoencephalography / Tony W. Wilson
  • Multiphoton Brain Imaging / Anna Dunaevsky
  • Part VII. Neuroelectrophysiology
  • Techniques for Extracellular Recordings / Jingdong Zhang, Jianxun Xia and Huangui Xiong
  • Blind Patch-Clamp Recordings from Rodent Hippocampal Slices / Jianxun Xia and Huangui Xiong
  • Whole-Cell Patch-Clamp Recording / Matthew J. Van Hook and Wallace B. Thoreson
  • Part VIII. Immunohistochemistry and Autoradiography
  • Analysis of Receptor Binding and Quantitative Autoradiography / L. Charles Murrin
  • Techniques in Immunohistochemistry and Immunocytochemistry / Yang Yuan and Jyothi Arikkath
  • Part IX. Analysis of Gene Expression
  • Protein Identification by Mass Spectrometry: Proteomics / Melinda Wojtkiewicz, Kelley Barnett and Pawel Ciborowski
  • DNA Microarrays as a Tool for Neurosciences Research / James D. Eudy, Lynette Smith
  • Metabolomics / Yazen Alnouti
  • Bioinformatic Methods and Resources for Neuroscience Research / Chittibabu Guda
  • Part X. Animal Models: Behavior and Pathology
  • Motor Function in Rodent Models of Neurodegenerative Disorders / Jessica A. Hutter Saunders, Max V. Kuenstling, Robert A. Weir, R. Lee Mosley and Howard E. Gendelman
  • Humanized Mice / Larisa Y. Poluektova and Edward Makarov
  • Animal Models for PD and ALS / Max V. Kuenstling, Adam M. Szlachetka and R. Lee Mosley
  • Animal Models of Alzheimer's Disease / Tomomi Kiyota
  • Animal Models: Behavior and Pathology: Preclinical Assessment of the Putative Cognitive Deficits in HAND / Landhing M. Moran, Rosemarie M. Booze and Charles F. Mactutus.
Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a blueprint for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
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Book
1 online resource.
Mathematical Neuroscience is a book for mathematical biologists seeking to discover the complexities of brain dynamics in an integrative way. It is the first research monograph devoted exclusively to the theory and methods of nonlinear analysis of infinite systems based on functional analysis techniques arising in modern mathematics. Neural models that describe the spatio-temporal evolution of coarse-grained variables - such as synaptic or firing rate activity in populations of neurons - and often take the form of integro-differential equations would not normally reflect an integrative approach. This book examines the solvability of infinite systems of reaction diffusion type equations in partially ordered abstract spaces. It considers various methods and techniques of nonlinear analysis, including comparison theorems, monotone iterative techniques, a truncation method, and topological fixed point methods. Infinite systems of such equations play a crucial role in the integrative aspects of neuroscience modeling. The first focused introduction to the use of nonlinear analysis with an infinite dimensional approach to theoretical neuroscience. It combines functional analysis techniques with nonlinear dynamical systems applied to the study of the brain. It introduces powerful mathematical techniques to manage the dynamics and challenges of infinite systems of equations applied to neuroscience modeling.
(source: Nielsen Book Data)
Mathematical Neuroscience is a book for mathematical biologists seeking to discover the complexities of brain dynamics in an integrative way. It is the first research monograph devoted exclusively to the theory and methods of nonlinear analysis of infinite systems based on functional analysis techniques arising in modern mathematics. Neural models that describe the spatio-temporal evolution of coarse-grained variables - such as synaptic or firing rate activity in populations of neurons - and often take the form of integro-differential equations would not normally reflect an integrative approach. This book examines the solvability of infinite systems of reaction diffusion type equations in partially ordered abstract spaces. It considers various methods and techniques of nonlinear analysis, including comparison theorems, monotone iterative techniques, a truncation method, and topological fixed point methods. Infinite systems of such equations play a crucial role in the integrative aspects of neuroscience modeling. The first focused introduction to the use of nonlinear analysis with an infinite dimensional approach to theoretical neuroscience. It combines functional analysis techniques with nonlinear dynamical systems applied to the study of the brain. It introduces powerful mathematical techniques to manage the dynamics and challenges of infinite systems of equations applied to neuroscience modeling.
(source: Nielsen Book Data)
Book
1 online resource (xii, 132 pages) : ill. (some color). Digital: text file; PDF.
  • Opioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day
  • Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction
  • The Influence of Pain on Reward Processing: Current Literature and Prospects
  • Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward
  • Drug Addiction and Chronic Pain: A Review of Animal Models
  • Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary
  • Prenatal Exposure to Opioids
  • Opioids in an Evidence-Based World.
Using rodent models, this volume explores the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction.
(source: Nielsen Book Data)
  • Opioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day
  • Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction
  • The Influence of Pain on Reward Processing: Current Literature and Prospects
  • Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward
  • Drug Addiction and Chronic Pain: A Review of Animal Models
  • Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary
  • Prenatal Exposure to Opioids
  • Opioids in an Evidence-Based World.
Using rodent models, this volume explores the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction.
(source: Nielsen Book Data)
Book
1 online resource (1 v.) : ill.
The world of coaching is competitive. Organisations want coaches who deliver results, and can prove it. Many coaching tools and techniques are now fairly well established - but how do they actually work? The coach who can answer this question credibly and convincingly is sought after. This ground-breaking book equips coaches with cutting edge neuroscience information that will help them deliver greater value to their clients. It covers the foundations that coaches need to be aware of and crucially, the ways they can use this new information effectively and practically in their everyday work. Readers will strengthen their kitbag of coaching tools and will be able to explain to their clients the neurological underpinning of the techniques they are using. No forward-thinking coach can afford to be ignorant of recent scientific developments: Neuroscience for Coaches will give them the practical knowledge they need.
(source: Nielsen Book Data)
The world of coaching is competitive. Organisations want coaches who deliver results, and can prove it. Many coaching tools and techniques are now fairly well established - but how do they actually work? The coach who can answer this question credibly and convincingly is sought after. This ground-breaking book equips coaches with cutting edge neuroscience information that will help them deliver greater value to their clients. It covers the foundations that coaches need to be aware of and crucially, the ways they can use this new information effectively and practically in their everyday work. Readers will strengthen their kitbag of coaching tools and will be able to explain to their clients the neurological underpinning of the techniques they are using. No forward-thinking coach can afford to be ignorant of recent scientific developments: Neuroscience for Coaches will give them the practical knowledge they need.
(source: Nielsen Book Data)
Book
1 online resource (x, 174 pages) : illustrations (some color)
  • 1 Introduction (Kazunori Sango and Junji Yamauchi)
  • 2 Recent insights into molecular mechanisms that control growth factor receptor-mediated Schwann cell morphological changes during development (Yuki Miyamoto and Junji Yamauchi)
  • 3 Membrane Skeleton in Schmidt-Lanterman Incisure in Schwann cells of Peripheral Nervous System (Nobuo Terada, Yurika Saitoh, Nobuhiko Ohno, and Shinichi Ohno)
  • 4 Schwann cell-axon interactions: the molecular and metabolic link between Schwann cells and axons (Nobuhiko Ohno, Takashi Sakoh, Yurika Saitoh, Nobuo Terada, and Shinichi Ohno)
  • 5 Schwann cell-dependent regulation of peripheral nerve injury and repair (Keiichiro Susuki )
  • 6 Charcot-Marie-Tooth disease (Toru Ogata)
  • 7 Expression of the transthyretin gene in Schwann cells, and familial amyloidotic polyneuropathy-mediated neurodegeneration (Tatsufumi Murakami and Yoshihide Sunada)
  • 8 Node of Ranvier disruption: a key pathophysiology in immune-mediated neuropathies (Keiichiro Susuki )
  • 9 Pathogenesis of diabetic neuropathy from the viewpoint of Schwann cell abnormalities (Koichi Kato, Eva L. Feldman, and Jiro Nakamura)
  • 10 Spontaneously immortalized adult rodent Schwann cells as valuable tools for the study of peripheral nerve degeneration and regeneration (Kazunori Sango, Masami Tsukamoto, Kazunori Utsunomiya, and Kazuhiko Watabe)
  • BM Index.
This book presents recent topics on the development, differentiation, and myelination of Schwann cells, as well as pathological mechanisms and therapeutic approaches for peripheral neuropathies, such as Charcot?Marie?Tooth diseases, amyloid polyneuropathy, immune-mediated neuropathy, and diabetic neuropathy. The rapid progress of molecular biological techniques in the last decades, especially for RNA techniques and gene modification technologies, have allowed us to investigate the pathobiology of Schwann cells in vivo and in vitro. Studies combining recent stem cell biology with recent biotechnology, which is now closely linked to physicochemical fields, further explain how Schwann cell lineages develop, a process that has long been thought to be very complicated in vivo. The findings contribute to the elucidation of fundamental mechanisms during development and under pathological conditions. We now know that these are closely tied to each other. This book also introduces unique coculture systems to reproduce the neuron Schwann cell interplay during development, degeneration, and regeneration. Up-to-date research topics with high-quality immunofluorescence and electron micrographs introduced by young and energetic contributors are sure to arouse the readers' interest in Schwann cell biology. Discussion from the viewpoint of basic and clinical neuroscience makes the book educational for researchers, medical students, and young clinicians.
  • 1 Introduction (Kazunori Sango and Junji Yamauchi)
  • 2 Recent insights into molecular mechanisms that control growth factor receptor-mediated Schwann cell morphological changes during development (Yuki Miyamoto and Junji Yamauchi)
  • 3 Membrane Skeleton in Schmidt-Lanterman Incisure in Schwann cells of Peripheral Nervous System (Nobuo Terada, Yurika Saitoh, Nobuhiko Ohno, and Shinichi Ohno)
  • 4 Schwann cell-axon interactions: the molecular and metabolic link between Schwann cells and axons (Nobuhiko Ohno, Takashi Sakoh, Yurika Saitoh, Nobuo Terada, and Shinichi Ohno)
  • 5 Schwann cell-dependent regulation of peripheral nerve injury and repair (Keiichiro Susuki )
  • 6 Charcot-Marie-Tooth disease (Toru Ogata)
  • 7 Expression of the transthyretin gene in Schwann cells, and familial amyloidotic polyneuropathy-mediated neurodegeneration (Tatsufumi Murakami and Yoshihide Sunada)
  • 8 Node of Ranvier disruption: a key pathophysiology in immune-mediated neuropathies (Keiichiro Susuki )
  • 9 Pathogenesis of diabetic neuropathy from the viewpoint of Schwann cell abnormalities (Koichi Kato, Eva L. Feldman, and Jiro Nakamura)
  • 10 Spontaneously immortalized adult rodent Schwann cells as valuable tools for the study of peripheral nerve degeneration and regeneration (Kazunori Sango, Masami Tsukamoto, Kazunori Utsunomiya, and Kazuhiko Watabe)
  • BM Index.
This book presents recent topics on the development, differentiation, and myelination of Schwann cells, as well as pathological mechanisms and therapeutic approaches for peripheral neuropathies, such as Charcot?Marie?Tooth diseases, amyloid polyneuropathy, immune-mediated neuropathy, and diabetic neuropathy. The rapid progress of molecular biological techniques in the last decades, especially for RNA techniques and gene modification technologies, have allowed us to investigate the pathobiology of Schwann cells in vivo and in vitro. Studies combining recent stem cell biology with recent biotechnology, which is now closely linked to physicochemical fields, further explain how Schwann cell lineages develop, a process that has long been thought to be very complicated in vivo. The findings contribute to the elucidation of fundamental mechanisms during development and under pathological conditions. We now know that these are closely tied to each other. This book also introduces unique coculture systems to reproduce the neuron Schwann cell interplay during development, degeneration, and regeneration. Up-to-date research topics with high-quality immunofluorescence and electron micrographs introduced by young and energetic contributors are sure to arouse the readers' interest in Schwann cell biology. Discussion from the viewpoint of basic and clinical neuroscience makes the book educational for researchers, medical students, and young clinicians.
Book
1 online resource.
  • Introductory concepts
  • Making Sense of Stress: An Evolutionary--Developmental Framework / Marco Del Giudice, Bruce J. Ellis, Elizabeth A. Shirtcliff
  • Prenatal and Maternal Psychosocial Stress in Primates: Adaptive Plasticity or Vulnerability to Pathology? / Dario Maestripieri, Amanda C. E. Klimczuk
  • Adaptive and maladaptive consequences of developmental stress in humans
  • The Everyday Stress Resilience Hypothesis: Unfolding Resilience from a Perspective of Everyday Stress and Coping / Jennifer A. DiCorcia, Akhila V. Sravish, Ed Tronick
  • Ontogeny of Stress Reactivity in the Human Child: Phenotypic Flexibility, Trade-Offs, and Pathology / Mark V. Flinn, Davide Ponzi, Pablo Nepomnaschy, Robert Noone
  • Consequences of Developmental Stress in Humans: Prenatal Stress / Nadine Skoluda, Urs M. Nater
  • Consequences of Developmental Stress in Humans: Adversity Experienced During Childhood and Adolescence / Urs M. Nater, Nadine Skoluda
  • Adaptive and maladaptive consequences of developmental stress in animal models
  • Behavioural and Neuroendocrine Consequences of Prenatal Stress in Rat / Sara Morley-Fletcher, Jérôme Mairesse, Stefania Maccari
  • Developmental Consequences of Prenatal Administration of Glucocorticoids in Rodents and Primates / Jonas Hauser
  • Early Developmental Trajectories of Brain Development: New Directions in the Search for Early Determinants of Health and Longevity / F. Cirulli, A. Berry
  • Adaptive Regulations in Developing Rodents Following Neonatal Challenges / Laurence Coutellier
  • Adaptive and Maladaptive Regulations in Response to Environmental Stress in Adolescent Rodents / Simone Macrì, Giovanni Laviola
  • Oxidative Stress and Hormetic Responses in the Early Life of Birds / David Costantini.
  • Introductory concepts
  • Making Sense of Stress: An Evolutionary--Developmental Framework / Marco Del Giudice, Bruce J. Ellis, Elizabeth A. Shirtcliff
  • Prenatal and Maternal Psychosocial Stress in Primates: Adaptive Plasticity or Vulnerability to Pathology? / Dario Maestripieri, Amanda C. E. Klimczuk
  • Adaptive and maladaptive consequences of developmental stress in humans
  • The Everyday Stress Resilience Hypothesis: Unfolding Resilience from a Perspective of Everyday Stress and Coping / Jennifer A. DiCorcia, Akhila V. Sravish, Ed Tronick
  • Ontogeny of Stress Reactivity in the Human Child: Phenotypic Flexibility, Trade-Offs, and Pathology / Mark V. Flinn, Davide Ponzi, Pablo Nepomnaschy, Robert Noone
  • Consequences of Developmental Stress in Humans: Prenatal Stress / Nadine Skoluda, Urs M. Nater
  • Consequences of Developmental Stress in Humans: Adversity Experienced During Childhood and Adolescence / Urs M. Nater, Nadine Skoluda
  • Adaptive and maladaptive consequences of developmental stress in animal models
  • Behavioural and Neuroendocrine Consequences of Prenatal Stress in Rat / Sara Morley-Fletcher, Jérôme Mairesse, Stefania Maccari
  • Developmental Consequences of Prenatal Administration of Glucocorticoids in Rodents and Primates / Jonas Hauser
  • Early Developmental Trajectories of Brain Development: New Directions in the Search for Early Determinants of Health and Longevity / F. Cirulli, A. Berry
  • Adaptive Regulations in Developing Rodents Following Neonatal Challenges / Laurence Coutellier
  • Adaptive and Maladaptive Regulations in Response to Environmental Stress in Adolescent Rodents / Simone Macrì, Giovanni Laviola
  • Oxidative Stress and Hormetic Responses in the Early Life of Birds / David Costantini.
Book
1 online resource.
  • Part 1. Introduction
  • Adenosine and Metabolism--A Brief Historical Note / Bertil B. Fredholm. Part 2. Molecular biology, pharmacology, and cell biology of adenosine
  • Adenosine Metabolism, Adenosine Kinase, and Evolution / Jaoek Park and Radhey S. Gupta
  • Adenosine and Energy Metabolism--Relationship to Brain Bioenergetics / Xuesong Chen, Liang Hui and Jonathan D. Geiger
  • Adenosine and Autocrine Metabolic Regulation of Neuronal Activity / Masahito Kawamura Jr. and David N. Ruskin
  • Physiologic and Metabolic Regulation of Adenosine: Mechanisms / Chris G. Dulla and Susan A. Masino
  • The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books / Stephanie zur Nedden, Alexander S. Doney and Bruno G. Frenguelli
  • Downstream Pathways of Adenosine / Ana M. Sebastião, Sofia Cristóvão-Ferreira and Joaquim A. Ribeiro
  • Astrocytic ATP Release / Dustin J. Hines and Philip G. Haydon
  • Role of Striatal A2A Receptor Subpopulations in Neurological Disorders / Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart and Seema Gulyani, et al..
  • Part 3. Adenosine function and dysfunction in brain health and disease
  • Sleep and Adenosine: Human Studies / Tarja Porkka-Heiskanen
  • Adenosine and Other Purinergic Products in Circadian Timing / Christine Muheim and Steven A. Brown
  • Adenosine in the Immune System / György Haskó, Balázs Koscsó and Balázs Csóka
  • The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation / Kelly L. Drew and Tulasi R. Jinka
  • Adenosine and Stroke / Felicita Pedata, Anna Maria Pugliese, Francesca Corti and Alessia Melani
  • The Many Roles of Adenosine in Traumatic Brain Injury / Patrick M. Kochanek, Jonathan D. Verrier, Amy K. Wagner and Edwin K. Jackson
  • Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury / Kwaku D. Nantwi
  • Adenosine and Pain / Jana Sawynok
  • Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson's Disease / Annalisa Pinna, Nicola Simola, Lucia Frau and Micaela Morelli
  • Adenosine Receptors and Alzheimer's Disease / David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha and Antoine Leboucher, et al.
  • Adenosine Receptors in Huntington's Disease / David Blum, Alberto Martire, Sylvie Burnouf, Bernard Sablonnière and Pierre Krystkowiak, et al.
  • Adenosine and Multiple Sclerosis / María Victoria Sánchez-Gómez, Estibaliz González-Fernández, Rogelio O. Arellano and Carlos Matute
  • Adenosinergic Perspectives on Schizophrenia: Opportunity for an Integrative Synthesis / Benjamin K. Yee, Philipp Singer and Detlev Boison
  • The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation / John D. Salamone, Merce Correa, Patrick A. Randall, Eric J. Nunes and Marta Pardo, et al.
  • Adenosine and Autism: Physiological Symptoms and Metabolic Opportunities / Julia Svedova, Inge-Marie Eigsti and Susan A. Masino
  • Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes / Traci N. Plumb, Sarah R. Sterlace, Kelly A. Cavanaugh and Thomas R. Minor.
  • Part 4. Adenosine-based therapies
  • Disruption of Adenosine Homeostasis in Epilepsy and Therapeutic Adenosine Augmentation / Detlev Boison
  • Ketogenic Diet and Epilepsy: The Role of Adenosine / Jong M. Rho, Beth Zupec-Kania and Susan A. Masino
  • Silk: A Biocompatible and Biodegradable Biopolymer for Therapeutic Adenosine Delivery / Eleanor M. Pritchard, Detlev Boison and David L. Kaplan
  • Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy / Zsolt Kovács and Arpád Dobolyi.
  • Part 1. Introduction
  • Adenosine and Metabolism--A Brief Historical Note / Bertil B. Fredholm. Part 2. Molecular biology, pharmacology, and cell biology of adenosine
  • Adenosine Metabolism, Adenosine Kinase, and Evolution / Jaoek Park and Radhey S. Gupta
  • Adenosine and Energy Metabolism--Relationship to Brain Bioenergetics / Xuesong Chen, Liang Hui and Jonathan D. Geiger
  • Adenosine and Autocrine Metabolic Regulation of Neuronal Activity / Masahito Kawamura Jr. and David N. Ruskin
  • Physiologic and Metabolic Regulation of Adenosine: Mechanisms / Chris G. Dulla and Susan A. Masino
  • The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books / Stephanie zur Nedden, Alexander S. Doney and Bruno G. Frenguelli
  • Downstream Pathways of Adenosine / Ana M. Sebastião, Sofia Cristóvão-Ferreira and Joaquim A. Ribeiro
  • Astrocytic ATP Release / Dustin J. Hines and Philip G. Haydon
  • Role of Striatal A2A Receptor Subpopulations in Neurological Disorders / Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart and Seema Gulyani, et al..
  • Part 3. Adenosine function and dysfunction in brain health and disease
  • Sleep and Adenosine: Human Studies / Tarja Porkka-Heiskanen
  • Adenosine and Other Purinergic Products in Circadian Timing / Christine Muheim and Steven A. Brown
  • Adenosine in the Immune System / György Haskó, Balázs Koscsó and Balázs Csóka
  • The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation / Kelly L. Drew and Tulasi R. Jinka
  • Adenosine and Stroke / Felicita Pedata, Anna Maria Pugliese, Francesca Corti and Alessia Melani
  • The Many Roles of Adenosine in Traumatic Brain Injury / Patrick M. Kochanek, Jonathan D. Verrier, Amy K. Wagner and Edwin K. Jackson
  • Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury / Kwaku D. Nantwi
  • Adenosine and Pain / Jana Sawynok
  • Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson's Disease / Annalisa Pinna, Nicola Simola, Lucia Frau and Micaela Morelli
  • Adenosine Receptors and Alzheimer's Disease / David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha and Antoine Leboucher, et al.
  • Adenosine Receptors in Huntington's Disease / David Blum, Alberto Martire, Sylvie Burnouf, Bernard Sablonnière and Pierre Krystkowiak, et al.
  • Adenosine and Multiple Sclerosis / María Victoria Sánchez-Gómez, Estibaliz González-Fernández, Rogelio O. Arellano and Carlos Matute
  • Adenosinergic Perspectives on Schizophrenia: Opportunity for an Integrative Synthesis / Benjamin K. Yee, Philipp Singer and Detlev Boison
  • The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation / John D. Salamone, Merce Correa, Patrick A. Randall, Eric J. Nunes and Marta Pardo, et al.
  • Adenosine and Autism: Physiological Symptoms and Metabolic Opportunities / Julia Svedova, Inge-Marie Eigsti and Susan A. Masino
  • Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes / Traci N. Plumb, Sarah R. Sterlace, Kelly A. Cavanaugh and Thomas R. Minor.
  • Part 4. Adenosine-based therapies
  • Disruption of Adenosine Homeostasis in Epilepsy and Therapeutic Adenosine Augmentation / Detlev Boison
  • Ketogenic Diet and Epilepsy: The Role of Adenosine / Jong M. Rho, Beth Zupec-Kania and Susan A. Masino
  • Silk: A Biocompatible and Biodegradable Biopolymer for Therapeutic Adenosine Delivery / Eleanor M. Pritchard, Detlev Boison and David L. Kaplan
  • Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy / Zsolt Kovács and Arpád Dobolyi.
Book
1 online resource : ill.
  • How Autistic Persons Understand Words (Cerebral Organization of Word Meaning and Autism)
  • How Autistic Persons Perceive the World (Sensory-Motor Function Level in the Brain and Autism)
  • How Autistic Persons Perceive Faces (Cerebral Organization of Face Recognition and Autism)
  • How Autistic Persons Act in the World (Cerebral Organization of Movements and Autism)
  • How Autistic Persons Perceive Space and Spatial Relations (Where System in the Brain and Autism)
  • How Autistic Persons Feel (Cerebral Organization of Limbic Emotion and Autism)
  • Autistic Persons' Sense of Self (Cerebral Organization of Self and Autism)
  • The Left-Hemispheric Self in Autism Revisited
  • Pieces of Autism's Puzzle Fall into Place (Clinical-Brain Pattern of Autism).
  • How Autistic Persons Understand Words (Cerebral Organization of Word Meaning and Autism)
  • How Autistic Persons Perceive the World (Sensory-Motor Function Level in the Brain and Autism)
  • How Autistic Persons Perceive Faces (Cerebral Organization of Face Recognition and Autism)
  • How Autistic Persons Act in the World (Cerebral Organization of Movements and Autism)
  • How Autistic Persons Perceive Space and Spatial Relations (Where System in the Brain and Autism)
  • How Autistic Persons Feel (Cerebral Organization of Limbic Emotion and Autism)
  • Autistic Persons' Sense of Self (Cerebral Organization of Self and Autism)
  • The Left-Hemispheric Self in Autism Revisited
  • Pieces of Autism's Puzzle Fall into Place (Clinical-Brain Pattern of Autism).
Book
1 online resource.
  • Topic 1: Peripheral processing.- Chapter 1. Mosaic evolution of the mammalian auditory periphery.- Chapter 2. A computer model of the auditory periphery and its application to the study of hearing.- Chapter 3. A probabilistic account of absolute auditory thresholds and its possible physiological basis.- Chapter 4. Cochlear compression: Recent insights from behavioural experiments.- Chapter 5. Improved psychophysical methods to estimate peripheral gain and compression.- Chapter 6. Contralateral efferent regulation of human cochlear tuning: Behavioural observations and computer model simulations.- Chapter 7. Modeling effects of precursor duration on behavioral estimates of cochlear gain.- Chapter 8. Is overshoot caused by an efferent reduction in cochlear gain?.- Chapter 9. Accurate estimation of compression in simultaneous masking enables the simulation of hearing impairment for normal-hearing listeners.- Chapter 10. Modelling the distortion produced by cochlear compression.- Topic 2: Temporal fine structure and pitch.- Chapter 11. How independent are the pitch and the interaural-time-difference mechanisms that rely on temporal fine structure information?.- Chapter 12. On the limit of neural phase-locking to fine-structure in humans.- Chapter 13. Effects of sensorineural hearing loss on temporal coding of harmonic and inharmonic tone complexes in the auditory nerve.- Chapter 14. A glimpsing account of the role of temporal fine structure information in speech recognition.- Chapter 15. Assessing the possible role of frequency-shift detectors in the ability to hear out partials in complex tones.- Chapter 16. Pitch perception: Dissociating frequency from fundamental-frequency discrimination.- Chapter 17. Pitch perception for sequences of impulse responses whose scaling alternates at every cycle.- Chapter 18. Putting the tritone paradox into context: insights from neural population decoding and human psychophysics.- Topic 3: Enhancement and perceptual compensation.- Chapter 19. Spectral and level effects in auditory enhancement.- Chapter 20. Enhancement of increments in spectral amplitude: further evidence for a mechanism based on central adaptation.- Chapter 21. Differential sensitivity to appearing and disappearing objects in complex acoustic scenes.- Chapter 22. Perceptual compensation when isolated test words are heard in room reverberation.- Chapter 23. A new approach to sound source identification.- Topic 4: Binaural processing.- Chapter 24. Maps of ITD in the Nucleus Laminaris of the Barn Owl.- Chapter 25. The influence of the envelope waveform on binaural tuning of neurons in the inferior colliculus and its relation to binaural perception.- Chapter 26. No evidence for ITD-specific adaptation in the frequency following response.- Chapter 27. Interaural time difference thresholds as a function of frequency.- Chapter 28. Interaural time processing when stimulus bandwidth differs at the two ears C.A. Brown, .- Chapter 29. Neural correlates of the perception of sound source separation.- Chapter 30. When and how envelope "rate-limitations" affect processing of interaural temporal disparities conveyed by high-frequency stimuli.- Chapter 31. The sound source distance dependence of the acoustical cues to location and their encoding by neurons in the inferior colliculus - implications for the Duplex theory.- Chapter 32. Cochlear contributions to the precedence effect.- Chapter 33. Off-frequency BMLD: the role of monaural processing.- Chapter 34. Measuring the apparent width of auditory sources in normal and impaired hearing.- Chapter 35. Psychophysics of human echolocation.- Topic 5: Speech and temporal processing.- Chapter 36. Formant-frequency variation and its effects on across-formant grouping in speech perception.- Chapter 37. Do we need STRFs for cocktail parties? - On the relevance of physiologically motivated features for human speech perception derived from automatic speech recognition.- Chapter 38. Modeling speech intelligibility in adverse conditions.- Chapter 39. Better temporal neural coding with cochlear implants in awake animals.- Chapter 40. Effects of auditory nerve refractoriness and adaptation on auditory perception.- Chapter 41. Robust cortical encoding of slow temporal modulations of speech.- Chapter 42. Wideband monaural envelope correlation perception.- Chapter 43. Detection thresholds for amplitude modulations of tones in budgerigar (Melopsittacus undulatus).- Chapter 44. Phase discrimination ability in Mongolian gerbils provides evidence for possible processing mechanism of mistuning detection.- Topic 6: Auditory cortex and beyond. Chapter 45.- Stimulus-specific adaptation beyond pure tones.- Chapter 46. Mapping tonotopy in human auditory cortex.- Chapter 47. Cortical activity associated with the perception of temporal asymmetry in ramped and damped noises.- Chapter 48. Cortical representation of the combination of monaural and binaural unmasking.- Chapter 49. Processing of short auditory stimuli: The Rapid Audio Sequential Presentation paradigm (RASP).- Chapter 50. Integration of auditory and tactile inputs in musical meter perception.- Chapter 51. A dynamic system for the analysis of the acoustic features and valence of aversive sounds in the human brain.- Topic 7: Auditory scene analysis.- Chapter 52. Can comodulation masking release occur when frequency changes would promote perceptual segregation of the on-frequency and flanking bands?.- Chapter 53. Illusory auditory continuity despite neural evidence to the contrary.- Chapter 54. High-acuity spatial stream segregation .- Chapter 55. How early aging and environment interact in everyday listening: From brainstem to behaviour through modeling.- Chapter 56. Energetic and informational masking in a simulated restaurant environment.- Chapter 57. A computational model for the dynamic aspects of primitive auditory scene analysis.- Chapter 58. A naturalistic approach to the cocktail party.- Chapter 59. Temporal coherence and the streaming of complex sounds.- Index.
  • (source: Nielsen Book Data)
The International Symposium on Hearing is a highly-prestigious, triennial event where world-class scientists present and discuss the most recent advances in the field of hearing research in animals and humans. Presented papers range from basic to applied research, and are of interest neuroscientists, otolaryngologists, psychologists, and artificial intelligence researchers. Basic Aspects of Hearing: Physiology and Perception includes the best papers from the 2012 International Symposium on Hearing. Over 50 chapters focus on the relationship between auditory physiology, psychoacoustics, and computational modeling.
(source: Nielsen Book Data)
  • Topic 1: Peripheral processing.- Chapter 1. Mosaic evolution of the mammalian auditory periphery.- Chapter 2. A computer model of the auditory periphery and its application to the study of hearing.- Chapter 3. A probabilistic account of absolute auditory thresholds and its possible physiological basis.- Chapter 4. Cochlear compression: Recent insights from behavioural experiments.- Chapter 5. Improved psychophysical methods to estimate peripheral gain and compression.- Chapter 6. Contralateral efferent regulation of human cochlear tuning: Behavioural observations and computer model simulations.- Chapter 7. Modeling effects of precursor duration on behavioral estimates of cochlear gain.- Chapter 8. Is overshoot caused by an efferent reduction in cochlear gain?.- Chapter 9. Accurate estimation of compression in simultaneous masking enables the simulation of hearing impairment for normal-hearing listeners.- Chapter 10. Modelling the distortion produced by cochlear compression.- Topic 2: Temporal fine structure and pitch.- Chapter 11. How independent are the pitch and the interaural-time-difference mechanisms that rely on temporal fine structure information?.- Chapter 12. On the limit of neural phase-locking to fine-structure in humans.- Chapter 13. Effects of sensorineural hearing loss on temporal coding of harmonic and inharmonic tone complexes in the auditory nerve.- Chapter 14. A glimpsing account of the role of temporal fine structure information in speech recognition.- Chapter 15. Assessing the possible role of frequency-shift detectors in the ability to hear out partials in complex tones.- Chapter 16. Pitch perception: Dissociating frequency from fundamental-frequency discrimination.- Chapter 17. Pitch perception for sequences of impulse responses whose scaling alternates at every cycle.- Chapter 18. Putting the tritone paradox into context: insights from neural population decoding and human psychophysics.- Topic 3: Enhancement and perceptual compensation.- Chapter 19. Spectral and level effects in auditory enhancement.- Chapter 20. Enhancement of increments in spectral amplitude: further evidence for a mechanism based on central adaptation.- Chapter 21. Differential sensitivity to appearing and disappearing objects in complex acoustic scenes.- Chapter 22. Perceptual compensation when isolated test words are heard in room reverberation.- Chapter 23. A new approach to sound source identification.- Topic 4: Binaural processing.- Chapter 24. Maps of ITD in the Nucleus Laminaris of the Barn Owl.- Chapter 25. The influence of the envelope waveform on binaural tuning of neurons in the inferior colliculus and its relation to binaural perception.- Chapter 26. No evidence for ITD-specific adaptation in the frequency following response.- Chapter 27. Interaural time difference thresholds as a function of frequency.- Chapter 28. Interaural time processing when stimulus bandwidth differs at the two ears C.A. Brown, .- Chapter 29. Neural correlates of the perception of sound source separation.- Chapter 30. When and how envelope "rate-limitations" affect processing of interaural temporal disparities conveyed by high-frequency stimuli.- Chapter 31. The sound source distance dependence of the acoustical cues to location and their encoding by neurons in the inferior colliculus - implications for the Duplex theory.- Chapter 32. Cochlear contributions to the precedence effect.- Chapter 33. Off-frequency BMLD: the role of monaural processing.- Chapter 34. Measuring the apparent width of auditory sources in normal and impaired hearing.- Chapter 35. Psychophysics of human echolocation.- Topic 5: Speech and temporal processing.- Chapter 36. Formant-frequency variation and its effects on across-formant grouping in speech perception.- Chapter 37. Do we need STRFs for cocktail parties? - On the relevance of physiologically motivated features for human speech perception derived from automatic speech recognition.- Chapter 38. Modeling speech intelligibility in adverse conditions.- Chapter 39. Better temporal neural coding with cochlear implants in awake animals.- Chapter 40. Effects of auditory nerve refractoriness and adaptation on auditory perception.- Chapter 41. Robust cortical encoding of slow temporal modulations of speech.- Chapter 42. Wideband monaural envelope correlation perception.- Chapter 43. Detection thresholds for amplitude modulations of tones in budgerigar (Melopsittacus undulatus).- Chapter 44. Phase discrimination ability in Mongolian gerbils provides evidence for possible processing mechanism of mistuning detection.- Topic 6: Auditory cortex and beyond. Chapter 45.- Stimulus-specific adaptation beyond pure tones.- Chapter 46. Mapping tonotopy in human auditory cortex.- Chapter 47. Cortical activity associated with the perception of temporal asymmetry in ramped and damped noises.- Chapter 48. Cortical representation of the combination of monaural and binaural unmasking.- Chapter 49. Processing of short auditory stimuli: The Rapid Audio Sequential Presentation paradigm (RASP).- Chapter 50. Integration of auditory and tactile inputs in musical meter perception.- Chapter 51. A dynamic system for the analysis of the acoustic features and valence of aversive sounds in the human brain.- Topic 7: Auditory scene analysis.- Chapter 52. Can comodulation masking release occur when frequency changes would promote perceptual segregation of the on-frequency and flanking bands?.- Chapter 53. Illusory auditory continuity despite neural evidence to the contrary.- Chapter 54. High-acuity spatial stream segregation .- Chapter 55. How early aging and environment interact in everyday listening: From brainstem to behaviour through modeling.- Chapter 56. Energetic and informational masking in a simulated restaurant environment.- Chapter 57. A computational model for the dynamic aspects of primitive auditory scene analysis.- Chapter 58. A naturalistic approach to the cocktail party.- Chapter 59. Temporal coherence and the streaming of complex sounds.- Index.
  • (source: Nielsen Book Data)
The International Symposium on Hearing is a highly-prestigious, triennial event where world-class scientists present and discuss the most recent advances in the field of hearing research in animals and humans. Presented papers range from basic to applied research, and are of interest neuroscientists, otolaryngologists, psychologists, and artificial intelligence researchers. Basic Aspects of Hearing: Physiology and Perception includes the best papers from the 2012 International Symposium on Hearing. Over 50 chapters focus on the relationship between auditory physiology, psychoacoustics, and computational modeling.
(source: Nielsen Book Data)
Book
1 online resource.
  • Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / George F. Koob
  • Synaptic Effects Induced by Alcohol / David M. Lovinger and Marisa Roberto
  • Signaling Pathways Mediating Alcohol Effects / Dorit Ron and Robert O. Messing
  • Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / Bo Söderpalm and Mia Ericson
  • What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Gerald A. Deehan Jr., Mark S. Brodie and Zachary A. Rodd
  • Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / John C. Crabbe, Kenneth S. Kendler and Robert J. Hitzemann
  • Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Christina S. Barr
  • Genetically Selected Alcohol Preferring Rats to Model Human Alcoholism / Roberto Ciccocioppo
  • Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Ainhoa Bilbao
  • Modeling Alcohol Self-Administration in the Human Laboratory / Ulrich S. Zimmermann, Sean O'Connor and Vijay A. Ramchandani
  • Animal Models of Excessive Alcohol Consumption in Rodents / Howard C. Becker
  • Modeling Relapse Situations in the Human Laboratory / Rajita Sinha
  • Modeling Relapse in Animals / Rémi Martin-Fardon and Friedbert Weiss
  • Invertebrate Models of Alcoholism / Henrike Scholz and Julie A. Mustard
  • The Dopamine System in Mediating Alcohol Effects in Humans / K. Charlet, A. Beck and A. Heinz
  • Stimulant and Sedative Effects of Alcohol / Reuben A. Hendler, Vijay A. Ramchandani, Jodi Gilman and Daniel W. Hommer
  • Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Dieter J. Meyerhoff, Timothy C. Durazzo and Gabriele Ende
  • Translational Approaches to Medication Development / Selena Bartlett and Markus Heilig
  • New Pharmacological Treatment Strategies for Relapse Prevention / Rainer Spanagel and Valentina Vengeliene
  • The Challenge of Studying Parallel Behaviors in Humans and Animal Models / David N. Stephens, Hans S. Crombag and Theodora Duka
  • A Translational Approach to Novel Medication Development for Protracted Abstinence / Barbara J. Mason and Amanda E. Higley
  • New Approaches to Addiction Treatment Based on Learning and Memory / Falk Kiefer and Christina Dinter
  • Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Nicola C. Newton, Maeve O'Leary-Barrett and Patricia J. Conrod
  • Deep Brain Stimulation as a Therapy for Alcohol Addiction / Thomas F. Münte, Hans-Jochen Heinze and Veerle Visser-Vandewalle.
  • Theoretical Frameworks and Mechanistic Aspects of Alcohol Addiction: Alcohol Addiction as a Reward Deficit Disorder / George F. Koob
  • Synaptic Effects Induced by Alcohol / David M. Lovinger and Marisa Roberto
  • Signaling Pathways Mediating Alcohol Effects / Dorit Ron and Robert O. Messing
  • Neurocircuitry Involved in the Development of Alcohol Addiction: The Dopamine System and its Access Points / Bo Söderpalm and Mia Ericson
  • What is in that Drink: The Biological Actions of Ethanol, Acetaldehyde, and Salsolinol / Gerald A. Deehan Jr., Mark S. Brodie and Zachary A. Rodd
  • Modeling the Diagnostic Criteria for Alcohol Dependence with Genetic Animal Models / John C. Crabbe, Kenneth S. Kendler and Robert J. Hitzemann
  • Non-Human Primate Models of Alcohol-Related Phenotypes: The Influence of Genetic and Environmental Factors / Christina S. Barr
  • Genetically Selected Alcohol Preferring Rats to Model Human Alcoholism / Roberto Ciccocioppo
  • Advanced Transgenic Approaches to Understand Alcohol-Related Phenotypes in Animals / Ainhoa Bilbao
  • Modeling Alcohol Self-Administration in the Human Laboratory / Ulrich S. Zimmermann, Sean O'Connor and Vijay A. Ramchandani
  • Animal Models of Excessive Alcohol Consumption in Rodents / Howard C. Becker
  • Modeling Relapse Situations in the Human Laboratory / Rajita Sinha
  • Modeling Relapse in Animals / Rémi Martin-Fardon and Friedbert Weiss
  • Invertebrate Models of Alcoholism / Henrike Scholz and Julie A. Mustard
  • The Dopamine System in Mediating Alcohol Effects in Humans / K. Charlet, A. Beck and A. Heinz
  • Stimulant and Sedative Effects of Alcohol / Reuben A. Hendler, Vijay A. Ramchandani, Jodi Gilman and Daniel W. Hommer
  • Chronic Alcohol Consumption, Abstinence and Relapse: Brain Proton Magnetic Resonance Spectroscopy Studies in Animals and Humans / Dieter J. Meyerhoff, Timothy C. Durazzo and Gabriele Ende
  • Translational Approaches to Medication Development / Selena Bartlett and Markus Heilig
  • New Pharmacological Treatment Strategies for Relapse Prevention / Rainer Spanagel and Valentina Vengeliene
  • The Challenge of Studying Parallel Behaviors in Humans and Animal Models / David N. Stephens, Hans S. Crombag and Theodora Duka
  • A Translational Approach to Novel Medication Development for Protracted Abstinence / Barbara J. Mason and Amanda E. Higley
  • New Approaches to Addiction Treatment Based on Learning and Memory / Falk Kiefer and Christina Dinter
  • Adolescent Substance Misuse: Neurobiology and Evidence-Based Interventions / Nicola C. Newton, Maeve O'Leary-Barrett and Patricia J. Conrod
  • Deep Brain Stimulation as a Therapy for Alcohol Addiction / Thomas F. Münte, Hans-Jochen Heinze and Veerle Visser-Vandewalle.
Book
1 online resource.