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Book
1 online resource. Digital: text file; PDF.
Book
1 online resource (x, 350 pages).
Book
xii, 270 pages : illustrations (some color) ; 25 cm
  • States of matter related to pharmacuetical formulations / Beverly J. Sandmann, Ann Newman, and Gregory T. Knipp
  • Physical properties of solutions / Beverly Sandmann, Antoine Al-Achi, Robert Greenwood
  • Ionic equilibrium and buffers / Beverly Sandmann, Alekha K. Dash, Antoine Al-Achi, Robert Greenwood
  • Solubility, dissolution, and partitioning/ Beverly J. Sandmann and Mansoor M. Amiji
  • Mass transport / Mansoor M. Amiji
  • Complexation and protein binding / Mansoor M. Amiji
  • Dispersed systems / W. Cary Mobley
  • Interfacial phenomena / Maria Polikandritou Lambros and SHihong Li Nocolaou
  • Rheology / Maria Polikandritou Lambros
  • Chemical kinetics of pharmaceuticals / Thomas J. Cook.
  • States of matter related to pharmacuetical formulations / Beverly J. Sandmann, Ann Newman, and Gregory T. Knipp
  • Physical properties of solutions / Beverly Sandmann, Antoine Al-Achi, Robert Greenwood
  • Ionic equilibrium and buffers / Beverly Sandmann, Alekha K. Dash, Antoine Al-Achi, Robert Greenwood
  • Solubility, dissolution, and partitioning/ Beverly J. Sandmann and Mansoor M. Amiji
  • Mass transport / Mansoor M. Amiji
  • Complexation and protein binding / Mansoor M. Amiji
  • Dispersed systems / W. Cary Mobley
  • Interfacial phenomena / Maria Polikandritou Lambros and SHihong Li Nocolaou
  • Rheology / Maria Polikandritou Lambros
  • Chemical kinetics of pharmaceuticals / Thomas J. Cook.
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
RS403 .A676 2014 Unavailable On order Request
Book
1 online resource (vii, 200 pages) : illustrations (some color).
  • Next Generation Sequencing: Chemistry, Technology and Applications, by P. Hui
  • Application of Next Generation Sequencing to Molecular Diagnosis of Inherited Diseases, by W. Zhang, H. Cui, L.-J.C. Wong
  • Clinical Applications of the Latest Molecular Diagnostics in Noninvasive Prenatal Diagnosis, by K.C.A. Chan
  • The Role of Protein Structural Analysis in the Next Generation Sequencing Era, by W.W. Yue, D.S. Froese, P.E. Brennan
  • Emerging Applications of Single-Cell Diagnostics, by M. Shirai, T. Taniguchi, H. Kambara
  • Mass Spectrometry in High-Throughput Clinical Biomarker Assays: Multiple Reaction Monitoring, by C.E. Parker, D. Domanski, A.J. Percy, A.G. Chambers, A.G. Camenzind, D.S. Smith, C.H. Borchers
  • Advances in MALDI Mass Spectrometry in Clinical Diagnostic Applications, by E.W.Y. Ng, M.Y.M. Wong, T.C.W. Poon
  • Application of Mass Spectrometry in Newborn Screening: About Both Small Molecular Diseases and Lysosomal Storage Diseases, by W.-L. Hwu, Y.-H. Chien, N.-C. Lee, S.-F. Wang, S.-C. Chiang, L.-W. Hsu.
  • Next Generation Sequencing: Chemistry, Technology and Applications, by P. Hui
  • Application of Next Generation Sequencing to Molecular Diagnosis of Inherited Diseases, by W. Zhang, H. Cui, L.-J.C. Wong
  • Clinical Applications of the Latest Molecular Diagnostics in Noninvasive Prenatal Diagnosis, by K.C.A. Chan
  • The Role of Protein Structural Analysis in the Next Generation Sequencing Era, by W.W. Yue, D.S. Froese, P.E. Brennan
  • Emerging Applications of Single-Cell Diagnostics, by M. Shirai, T. Taniguchi, H. Kambara
  • Mass Spectrometry in High-Throughput Clinical Biomarker Assays: Multiple Reaction Monitoring, by C.E. Parker, D. Domanski, A.J. Percy, A.G. Chambers, A.G. Camenzind, D.S. Smith, C.H. Borchers
  • Advances in MALDI Mass Spectrometry in Clinical Diagnostic Applications, by E.W.Y. Ng, M.Y.M. Wong, T.C.W. Poon
  • Application of Mass Spectrometry in Newborn Screening: About Both Small Molecular Diseases and Lysosomal Storage Diseases, by W.-L. Hwu, Y.-H. Chien, N.-C. Lee, S.-F. Wang, S.-C. Chiang, L.-W. Hsu.
Book
1 online resource (xv, 415 pages)
Book
xii, 385 p. : ill.
  • ch. 1. Generic drug product development and therapeutic equivalence / Leon Shargel and Isadore Kanfer
  • ch. 2. Active pharmaceutical ingredients / Edward M. Cohen and Steven Sutherland
  • ch. 3. Analytical methods development and methods validation for oral solid dosage forms / Quanyin Gao and Dilip R. Sanvordeker
  • ch. 4. Experimental formulation development / Isadore Kanfer ... [et al.]
  • ch. 5. Scale-up, technology transfer, and process performance qualification / Salah U. Ahmed ... [et al.]
  • ch. 6. Drug stability / Pranab K. Bhattacharyya
  • ch. 7. Quality control and quality assurance / Loren Gelber
  • ch. 8. Drug product performance : in vitro / Pradeep M. Sathe, John Duan, and Lawrence X. Yu
  • ch. 9. ANDA regulatory approval process / Timothy W. Ames and Aaron Sigler
  • ch. 10. Bioequivalence and drug product assessment : in vivo / Barbara M. Davit and Dale P. Conner
  • ch. 11. Statistical considerations for establishing bioequivalence / Charles Bon and Sanford Bolton
  • ch. 12. Outsourcing bioavailability and bioequivalence studies to contract research organizations / Patrick K. Noonan
  • ch. 13. Postapproval changes and postmarketing reporting of adverse drug experiences / Lorien Armour and Leon Shargel
  • ch. 14. The United States pharmacopeia/national formulary : its history, organization, and role in harmonization / William Brown and Margareth R.C. Marques
  • ch. 15. Legal and legislative hurdles to generic drug development, approval, and marketing / Arthur Y. Tsien.
"This book collects in-depth discussions from more than 30 noted specialists on topics such as quality control, experimental formulations, pharmaceutical ingredients, conventional and modified-release products, and bioequivalence. It considers key elements in the formulation of generic drug products including the availability of raw materials and chemical purity. It contains new chapters on experimental formulation development, and the relationship between the FDA and the United States Pharmacopeia"--Provided by publisher.
  • ch. 1. Generic drug product development and therapeutic equivalence / Leon Shargel and Isadore Kanfer
  • ch. 2. Active pharmaceutical ingredients / Edward M. Cohen and Steven Sutherland
  • ch. 3. Analytical methods development and methods validation for oral solid dosage forms / Quanyin Gao and Dilip R. Sanvordeker
  • ch. 4. Experimental formulation development / Isadore Kanfer ... [et al.]
  • ch. 5. Scale-up, technology transfer, and process performance qualification / Salah U. Ahmed ... [et al.]
  • ch. 6. Drug stability / Pranab K. Bhattacharyya
  • ch. 7. Quality control and quality assurance / Loren Gelber
  • ch. 8. Drug product performance : in vitro / Pradeep M. Sathe, John Duan, and Lawrence X. Yu
  • ch. 9. ANDA regulatory approval process / Timothy W. Ames and Aaron Sigler
  • ch. 10. Bioequivalence and drug product assessment : in vivo / Barbara M. Davit and Dale P. Conner
  • ch. 11. Statistical considerations for establishing bioequivalence / Charles Bon and Sanford Bolton
  • ch. 12. Outsourcing bioavailability and bioequivalence studies to contract research organizations / Patrick K. Noonan
  • ch. 13. Postapproval changes and postmarketing reporting of adverse drug experiences / Lorien Armour and Leon Shargel
  • ch. 14. The United States pharmacopeia/national formulary : its history, organization, and role in harmonization / William Brown and Margareth R.C. Marques
  • ch. 15. Legal and legislative hurdles to generic drug development, approval, and marketing / Arthur Y. Tsien.
"This book collects in-depth discussions from more than 30 noted specialists on topics such as quality control, experimental formulations, pharmaceutical ingredients, conventional and modified-release products, and bioequivalence. It considers key elements in the formulation of generic drug products including the availability of raw materials and chemical purity. It contains new chapters on experimental formulation development, and the relationship between the FDA and the United States Pharmacopeia"--Provided by publisher.
Book
xiv, 243 pages : illustrations (some color) ; 25 cm
  • Seduced by drug discovery
  • The small molecules of life
  • Proteins : molecular wonders in three dimensions
  • Proteins perform multiple functions : enzymes, receptors, ion channels
  • Drug discovery and development : the road from an idea to promoting human health
  • Finasteride : the Gary and Jerry show
  • Basic research, snake venoms, and ACE inhibitors : Ondetti, Cushman, and Patchett
  • Statins : protection against heart attacks and strokes
  • The perils of primaxin
  • Avermectins : molecules of life battle parasites
  • Fludalanine : nice try but no hallelujah
  • Diabetes breakthrough : Januvia and Janumet.
  • Seduced by drug discovery
  • The small molecules of life
  • Proteins : molecular wonders in three dimensions
  • Proteins perform multiple functions : enzymes, receptors, ion channels
  • Drug discovery and development : the road from an idea to promoting human health
  • Finasteride : the Gary and Jerry show
  • Basic research, snake venoms, and ACE inhibitors : Ondetti, Cushman, and Patchett
  • Statins : protection against heart attacks and strokes
  • The perils of primaxin
  • Avermectins : molecules of life battle parasites
  • Fludalanine : nice try but no hallelujah
  • Diabetes breakthrough : Januvia and Janumet.
Green Library
Status of items at Green Library
Green Library Status
HAS New Books (Lane Room) Find it
RM301.25 .C67 2014 Unknown
Book
1 online resource (xiii, 119 pages) : illustrations.
The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a first volume which presents collection of best papers presented in the First International Conference on Infectious Diseases and Nanomedicine held during Dec. 15-18, 2012 in Kathmandu, Nepal. The book focuses mainly on the topics: emerging infectious diseases; antimicrobial agents, vaccines and immunity; drug design, drug delivery and tissue engineering; and nanomaterials and biomedical materials.
The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a first volume which presents collection of best papers presented in the First International Conference on Infectious Diseases and Nanomedicine held during Dec. 15-18, 2012 in Kathmandu, Nepal. The book focuses mainly on the topics: emerging infectious diseases; antimicrobial agents, vaccines and immunity; drug design, drug delivery and tissue engineering; and nanomaterials and biomedical materials.
Book
1 online resource (xv, 61 pages) : illustrations (some color).
Book
1 online resource.
Book
xiii, 418 p. : ill. ; 26 cm.
  • A brief history of drug discovery
  • The modern drug process
  • A trip through the body
  • Enzymes as drug targets
  • Receptors as drug targets
  • Oligonucleotides as drug targets
  • Pharmacokinetics
  • Metabolism
  • Molecular structure and diversity
  • Lead discovery
  • Lead optimization : traditional methods
  • Lead optimization : Hansch analysis
  • Aspects in pharmaceutical synthesis.
  • A brief history of drug discovery
  • The modern drug process
  • A trip through the body
  • Enzymes as drug targets
  • Receptors as drug targets
  • Oligonucleotides as drug targets
  • Pharmacokinetics
  • Metabolism
  • Molecular structure and diversity
  • Lead discovery
  • Lead optimization : traditional methods
  • Lead optimization : Hansch analysis
  • Aspects in pharmaceutical synthesis.
Chemistry & ChemEng Library (Swain)
Status of items at Chemistry & ChemEng Library (Swain)
Chemistry & ChemEng Library (Swain) Status
Stacks
RS403 .S745 2014 Unknown
Book
1 online resource.
  • Introduction
  • Lead discovery and lead modification
  • Receptors
  • Enzymes
  • Enzyme inhibition and inactivation
  • Dna-interactive agents
  • Drug resistance and drug synergism
  • Drug metabolism
  • Prodrugs and drug delivery systems.
  • Introduction
  • Lead discovery and lead modification
  • Receptors
  • Enzymes
  • Enzyme inhibition and inactivation
  • Dna-interactive agents
  • Drug resistance and drug synergism
  • Drug metabolism
  • Prodrugs and drug delivery systems.
Book
online resource (xxvii, 1039 pages) : illustrations
Medical Library (Lane)
Status of items at Medical Library (Lane)
Medical Library (Lane) Status
Check Medical Library (Lane) catalog for status
CRCNETBASE Unknown
Book
1 online resource (xxvi, 698 pages)
  • Introduction to biopharmaceuticals
  • Distinctions of biologic versus small molecule platforms in drug development
  • Financing biologic drug development
  • Application of biotechnology in drug discovery and early development
  • Large-scale production of recombinant proteins
  • Clinical pharmacology, toxicology, and therapeutic dosage & response
  • Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals
  • Pharmacoeconomics and drug pricing / Garrison
  • Antibodies and derivatives
  • Hematopoietic growth and coagulation factors
  • Cytokines and interferons
  • Hormones
  • Enzymes
  • Vaccines / Hu, Ho
  • Other biopharmaceutical products
  • Advances in personalized medicine : pharmacogenetics in drug therapy
  • Gene and cell therapy
  • Pharmacoeconomics, outcome, and health technology assessment research in drug development
  • Summary and future prospects.
  • Introduction to biopharmaceuticals
  • Distinctions of biologic versus small molecule platforms in drug development
  • Financing biologic drug development
  • Application of biotechnology in drug discovery and early development
  • Large-scale production of recombinant proteins
  • Clinical pharmacology, toxicology, and therapeutic dosage & response
  • Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals
  • Pharmacoeconomics and drug pricing / Garrison
  • Antibodies and derivatives
  • Hematopoietic growth and coagulation factors
  • Cytokines and interferons
  • Hormones
  • Enzymes
  • Vaccines / Hu, Ho
  • Other biopharmaceutical products
  • Advances in personalized medicine : pharmacogenetics in drug therapy
  • Gene and cell therapy
  • Pharmacoeconomics, outcome, and health technology assessment research in drug development
  • Summary and future prospects.
Book
1 online resource.
Book
online resource (xvi, 325 pages) : illustrations (some color)
  • Part 1. Chembiomolecular Chemistry
  • Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer / Yoshito Kishi
  • Practical Synthesis of Tamiflu and Beyond / Motomu Kanai
  • An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis / Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai and Futoshi Hasegawa, et al.
  • Inhibitors of Fatty Acid Amide Hydrolase / Dale L. Boger
  • Small Molecule Tools for Cell Biology and Cell Therapy / Motonari Uesugi
  • Toward the Discovery of Small Molecules Affecting RNA Function / Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi and Asako Murata, et al.
  • New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases / Go Hirai, Ayako Tsuchiya and Mikiko Sodeoka
  • The Deep Oceans as a Source for New Treatments for Cancer / William Fenical, James J. La Clair, Chambers C. Hughes, Paul R. Jensen and Susana P. Gaudêncio, et al.
  • Search for New Medicinal Seeds from Marine Organisms / Motomasa Kobayashi, Naoyuki Kotoku and Masayoshi Arai
  • Identification of Protein-Small Molecule Interactions by Chemical Array / Hiroyuki Osada and Siro Simizu
  • Part 2. Chembiomolecular Biology
  • Small Molecule-Induced Proximity / Fu-Sen Liang and Gerald R. Crabtree
  • High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing / Erik S. Anderson, Peter Stoilov, Robert Damoiseaux and Douglas L. Black
  • Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans / Masaharu Uno, Sakiko Honjoh and Eisuke Nishida
  • Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis / Miki Kamiyama, Takehiro Sato, Kohsuke Takeda and Hidenori Ichijo
  • Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal / Laura L. Kiessling
  • Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis / Reiji Kannagi, Keiichiro Sakuma and Katsuyuki Ohmori
  • Establishment of a Novel System for Studying the Syk Function in B Cells / Tomohiro Kurosaki and Clifford A. Lowell
  • Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures / Kaya Shigaki, Kazuaki Tokunaga, Yuki Mihara, Yota Matsuo and Yamato Kojimoto, et al.
  • Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases / Shinji Oki, Benjamin J. E. Raveney, Yoshimitsu Doi and Takashi Yamamura
  • Antiviral MicroRNA / Ryota Ouda and Takashi Fujita
  • Synaptic Function Monitored Using Chemobiomolecular Indicators / Masamitsu Iino
  • Part 3. Chembiomolecular Medicinal Chemistry
  • Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate / Masakatsu Shibasaki
  • Hunting the Targets of Natural Product-Inspired Compounds / Slava Ziegler and Herbert Waldmann
  • Chemical Approaches for Understanding and Controlling Infectious Diseases / Hirokazu Arimoto
  • Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-[gamma] Agonists / Hiroyuki Miyachi
  • Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase / Mark von Itzstein
  • Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases / Kunihiko Nishino
  • Enzymes as Chemotherapeutic Agents / Ronald T. Raines
  • Mechanism of Action of New Antiinfectious Agents from Microorganisms / Nobuhiro Koyama and Hiroshi Tomoda
  • Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease / Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung and C. Frank Bennett, et al.
  • Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications / Masatoshi Hagiwara.
At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.
  • Part 1. Chembiomolecular Chemistry
  • Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer / Yoshito Kishi
  • Practical Synthesis of Tamiflu and Beyond / Motomu Kanai
  • An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis / Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai and Futoshi Hasegawa, et al.
  • Inhibitors of Fatty Acid Amide Hydrolase / Dale L. Boger
  • Small Molecule Tools for Cell Biology and Cell Therapy / Motonari Uesugi
  • Toward the Discovery of Small Molecules Affecting RNA Function / Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi and Asako Murata, et al.
  • New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases / Go Hirai, Ayako Tsuchiya and Mikiko Sodeoka
  • The Deep Oceans as a Source for New Treatments for Cancer / William Fenical, James J. La Clair, Chambers C. Hughes, Paul R. Jensen and Susana P. Gaudêncio, et al.
  • Search for New Medicinal Seeds from Marine Organisms / Motomasa Kobayashi, Naoyuki Kotoku and Masayoshi Arai
  • Identification of Protein-Small Molecule Interactions by Chemical Array / Hiroyuki Osada and Siro Simizu
  • Part 2. Chembiomolecular Biology
  • Small Molecule-Induced Proximity / Fu-Sen Liang and Gerald R. Crabtree
  • High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing / Erik S. Anderson, Peter Stoilov, Robert Damoiseaux and Douglas L. Black
  • Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans / Masaharu Uno, Sakiko Honjoh and Eisuke Nishida
  • Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis / Miki Kamiyama, Takehiro Sato, Kohsuke Takeda and Hidenori Ichijo
  • Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal / Laura L. Kiessling
  • Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis / Reiji Kannagi, Keiichiro Sakuma and Katsuyuki Ohmori
  • Establishment of a Novel System for Studying the Syk Function in B Cells / Tomohiro Kurosaki and Clifford A. Lowell
  • Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures / Kaya Shigaki, Kazuaki Tokunaga, Yuki Mihara, Yota Matsuo and Yamato Kojimoto, et al.
  • Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases / Shinji Oki, Benjamin J. E. Raveney, Yoshimitsu Doi and Takashi Yamamura
  • Antiviral MicroRNA / Ryota Ouda and Takashi Fujita
  • Synaptic Function Monitored Using Chemobiomolecular Indicators / Masamitsu Iino
  • Part 3. Chembiomolecular Medicinal Chemistry
  • Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate / Masakatsu Shibasaki
  • Hunting the Targets of Natural Product-Inspired Compounds / Slava Ziegler and Herbert Waldmann
  • Chemical Approaches for Understanding and Controlling Infectious Diseases / Hirokazu Arimoto
  • Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-[gamma] Agonists / Hiroyuki Miyachi
  • Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase / Mark von Itzstein
  • Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases / Kunihiko Nishino
  • Enzymes as Chemotherapeutic Agents / Ronald T. Raines
  • Mechanism of Action of New Antiinfectious Agents from Microorganisms / Nobuhiro Koyama and Hiroshi Tomoda
  • Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease / Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung and C. Frank Bennett, et al.
  • Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications / Masatoshi Hagiwara.
At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.
Medical Library (Lane)
Status of items at Medical Library (Lane)
Medical Library (Lane) Status
Check Medical Library (Lane) catalog for status
SPRINGER Unknown
Book
1 online resource : col. ill.
  • Part 1. Chembiomolecular Chemistry
  • Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer / Yoshito Kishi
  • Practical Synthesis of Tamiflu and Beyond / Motomu Kanai
  • An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis / Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai and Futoshi Hasegawa, et al.
  • Inhibitors of Fatty Acid Amide Hydrolase / Dale L. Boger
  • Small Molecule Tools for Cell Biology and Cell Therapy / Motonari Uesugi
  • Toward the Discovery of Small Molecules Affecting RNA Function / Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi and Asako Murata, et al.
  • New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases / Go Hirai, Ayako Tsuchiya and Mikiko Sodeoka
  • The Deep Oceans as a Source for New Treatments for Cancer / William Fenical, James J. La Clair, Chambers C. Hughes, Paul R. Jensen and Susana P. Gaudêncio, et al.
  • Search for New Medicinal Seeds from Marine Organisms / Motomasa Kobayashi, Naoyuki Kotoku and Masayoshi Arai
  • Identification of Protein-Small Molecule Interactions by Chemical Array / Hiroyuki Osada and Siro Simizu.
  • Part 2. Chembiomolecular Biology
  • Small Molecule-Induced Proximity / Fu-Sen Liang and Gerald R. Crabtree
  • High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing / Erik S. Anderson, Peter Stoilov, Robert Damoiseaux and Douglas L. Black
  • Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans / Masaharu Uno, Sakiko Honjoh and Eisuke Nishida
  • Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis / Miki Kamiyama, Takehiro Sato, Kohsuke Takeda and Hidenori Ichijo
  • Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal / Laura L. Kiessling
  • Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis / Reiji Kannagi, Keiichiro Sakuma and Katsuyuki Ohmori
  • Establishment of a Novel System for Studying the Syk Function in B Cells / Tomohiro Kurosaki and Clifford A. Lowell
  • Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures / Kaya Shigaki, Kazuaki Tokunaga, Yuki Mihara, Yota Matsuo and Yamato Kojimoto, et al.
  • Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases / Shinji Oki, Benjamin J. E. Raveney, Yoshimitsu Doi and Takashi Yamamura
  • Antiviral MicroRNA / Ryota Ouda and Takashi Fujita
  • Synaptic Function Monitored Using Chemobiomolecular Indicators / Masamitsu Iino.
  • Part 3. Chembiomolecular Medicinal Chemistry
  • Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate / Masakatsu Shibasaki
  • Hunting the Targets of Natural Product-Inspired Compounds / Slava Ziegler and Herbert Waldmann
  • Chemical Approaches for Understanding and Controlling Infectious Diseases / Hirokazu Arimoto
  • Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-[gamma] Agonists / Hiroyuki Miyachi
  • Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase / Mark von Itzstein
  • Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases / Kunihiko Nishino
  • Enzymes as Chemotherapeutic Agents / Ronald T. Raines
  • Mechanism of Action of New Antiinfectious Agents from Microorganisms / Nobuhiro Koyama and Hiroshi Tomoda
  • Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease / Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung and C. Frank Bennett, et al.
  • Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications / Masatoshi Hagiwara.
At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.
  • Part 1. Chembiomolecular Chemistry
  • Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer / Yoshito Kishi
  • Practical Synthesis of Tamiflu and Beyond / Motomu Kanai
  • An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis / Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai and Futoshi Hasegawa, et al.
  • Inhibitors of Fatty Acid Amide Hydrolase / Dale L. Boger
  • Small Molecule Tools for Cell Biology and Cell Therapy / Motonari Uesugi
  • Toward the Discovery of Small Molecules Affecting RNA Function / Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi and Asako Murata, et al.
  • New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases / Go Hirai, Ayako Tsuchiya and Mikiko Sodeoka
  • The Deep Oceans as a Source for New Treatments for Cancer / William Fenical, James J. La Clair, Chambers C. Hughes, Paul R. Jensen and Susana P. Gaudêncio, et al.
  • Search for New Medicinal Seeds from Marine Organisms / Motomasa Kobayashi, Naoyuki Kotoku and Masayoshi Arai
  • Identification of Protein-Small Molecule Interactions by Chemical Array / Hiroyuki Osada and Siro Simizu.
  • Part 2. Chembiomolecular Biology
  • Small Molecule-Induced Proximity / Fu-Sen Liang and Gerald R. Crabtree
  • High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing / Erik S. Anderson, Peter Stoilov, Robert Damoiseaux and Douglas L. Black
  • Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans / Masaharu Uno, Sakiko Honjoh and Eisuke Nishida
  • Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis / Miki Kamiyama, Takehiro Sato, Kohsuke Takeda and Hidenori Ichijo
  • Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal / Laura L. Kiessling
  • Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis / Reiji Kannagi, Keiichiro Sakuma and Katsuyuki Ohmori
  • Establishment of a Novel System for Studying the Syk Function in B Cells / Tomohiro Kurosaki and Clifford A. Lowell
  • Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures / Kaya Shigaki, Kazuaki Tokunaga, Yuki Mihara, Yota Matsuo and Yamato Kojimoto, et al.
  • Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases / Shinji Oki, Benjamin J. E. Raveney, Yoshimitsu Doi and Takashi Yamamura
  • Antiviral MicroRNA / Ryota Ouda and Takashi Fujita
  • Synaptic Function Monitored Using Chemobiomolecular Indicators / Masamitsu Iino.
  • Part 3. Chembiomolecular Medicinal Chemistry
  • Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate / Masakatsu Shibasaki
  • Hunting the Targets of Natural Product-Inspired Compounds / Slava Ziegler and Herbert Waldmann
  • Chemical Approaches for Understanding and Controlling Infectious Diseases / Hirokazu Arimoto
  • Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-[gamma] Agonists / Hiroyuki Miyachi
  • Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase / Mark von Itzstein
  • Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases / Kunihiko Nishino
  • Enzymes as Chemotherapeutic Agents / Ronald T. Raines
  • Mechanism of Action of New Antiinfectious Agents from Microorganisms / Nobuhiro Koyama and Hiroshi Tomoda
  • Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease / Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung and C. Frank Bennett, et al.
  • Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications / Masatoshi Hagiwara.
At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.
Book
xiv, 255 p. : ill. (some col.) ; 24 cm.
SAL1&2 (on-campus shelving)
Status of items at SAL1&2 (on-campus shelving)
SAL1&2 (on-campus shelving) Status
Stacks Request
RS403 .C4244 2013 Unknown

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