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Book
1 online resource.
  • An Introduction to Ambient Ionization Mass Spectrometry-- Direct Analysis in real time (DART(R))-- Ionization Mechanisms of Direct Analysis in Real Time (DART)-- Atmospheric Samples Analysis Probe (ASAP) Mass Spectrometry-- Ambient Analysis by Thermal Desorption Atmospheric Pressure Photoionization-- Low Temperature Plasma Probe-- Flowing Atmospheric Pressure Afterglow (FAPA), the Plasma-based Source for your ADI-MS needs-- Spray Desorption Collection and DESI Mechanisms-- Easy Ambient Sonic-Spray Ionization-- Secondary Electrospray Ionization-- Probe Electrospray Ionization-- Desorption Electrospray Mass Spectrometry-- Surface Acoustic Wave Nebulization-- Laser Ablation Electrospray Ionization Mass Spectrometry: Mechanisms, Configurations and Imaging Applications-- Electrospray Laser Desorption Ionization Mass Spectrometry-- Paper Spray-- Inlet and Vacuum Ionization from Ambient Conditions-- Enabling Automated Sample Analysis by Direct Analysis in Real Time (DART) Mass Spectrometry-- Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI(R)-MS): Ambient Ionization Technology for 2D and 3D Molecular Imaging-- Liquid Extraction Surface Analysis Mass Spectrometry (LESA MS): Combining Liquid Extraction, Surface Profiling and Ambient Ionization Mass Spectrometry in One Novel Analysis Technique-- Subject Index.
  • (source: Nielsen Book Data)
Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
(source: Nielsen Book Data)
  • An Introduction to Ambient Ionization Mass Spectrometry-- Direct Analysis in real time (DART(R))-- Ionization Mechanisms of Direct Analysis in Real Time (DART)-- Atmospheric Samples Analysis Probe (ASAP) Mass Spectrometry-- Ambient Analysis by Thermal Desorption Atmospheric Pressure Photoionization-- Low Temperature Plasma Probe-- Flowing Atmospheric Pressure Afterglow (FAPA), the Plasma-based Source for your ADI-MS needs-- Spray Desorption Collection and DESI Mechanisms-- Easy Ambient Sonic-Spray Ionization-- Secondary Electrospray Ionization-- Probe Electrospray Ionization-- Desorption Electrospray Mass Spectrometry-- Surface Acoustic Wave Nebulization-- Laser Ablation Electrospray Ionization Mass Spectrometry: Mechanisms, Configurations and Imaging Applications-- Electrospray Laser Desorption Ionization Mass Spectrometry-- Paper Spray-- Inlet and Vacuum Ionization from Ambient Conditions-- Enabling Automated Sample Analysis by Direct Analysis in Real Time (DART) Mass Spectrometry-- Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI(R)-MS): Ambient Ionization Technology for 2D and 3D Molecular Imaging-- Liquid Extraction Surface Analysis Mass Spectrometry (LESA MS): Combining Liquid Extraction, Surface Profiling and Ambient Ionization Mass Spectrometry in One Novel Analysis Technique-- Subject Index.
  • (source: Nielsen Book Data)
Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
(source: Nielsen Book Data)
Book
1 online resource (xv, 327 pages) : illustrations (some color) Digital: text file; PDF.
Book
1 online resource (xiv, 432 pages) : illustrations (some color).
  • Preventing Indoor Bioaerosols Contamination in Food Processing Environments and HVAC-systems: Assessment of Particle Deposition for Hygienic Design Purposes
  • The OASIS Observatory Using Ground-Based Solar Absorption Fourier Transform Infrared Spectroscopy in the Suburbs of Paris (Créteil-France)
  • Daytime Atmospheric Chemistry of C4-C7 Saturated and Unsaturated Carbonyl Compounds
  • Night-time Atmospheric Reactivity of Some Oxygenated Organic Compounds
  • Mercury Soil Pollution in Spain: A Review
  • The Role of Earthworms in Mercury Pollution Soil Assessment
  • Pb-Zn-Cd-As Pollution in Soils Affected by Mining Activities in Central and Southern Spain: a Scattered Legacy Posing Potential Environmental and Health Concerns
  • In Situ Chemical Oxidation Based on Hydrogen Peroxide: Optimization of Its Application to an Hydrocarbon Polluted Site
  • Sustainable Polyurethanes? Chemical Recycling to Get It
  • Polystyrene Wastes, Threat or Opportunity?- Microbial Fuel Cell: the Definitive Technological Approach for Valorizing Organic Wastes?- Removal of Organic Pollutants from Industrial Wastewater by Treatment with Oxidoreductase Enzymes
  • Livestock Waste: Fears and Opportunities
  • Greenhouse Effect Mitigation Through Photocatalytic Technology
  • Microwaves in Green and Sustainable Chemistry.
This volume offers a comprehensive overview of advanced research in the field of environmental green chemistry for air, soil and water pollutants, and presents emerging technologies on the chemical treatment of polluted sites and wastes. The 15 chapters, prepared by internationally respected experts, address the following topics: (1) monitoring of indoor and outdoor air pollutants; (2) atmospheric degradation processes and formation mechanisms of secondary pollutants; (3) the environmental assessment and impacts of soils polluted by heavy metals and hydrocarbons; (4) sustainable and emerging technologies for the chemical treatment of organic and animal wastes and wastewaters; (5) photocatalytic CO2 conversion methods for the mitigation of greenhouse effects; and (6) non-conventional methods in green chemistry synthesis. Lastly, the authors outline the future perspectives of each topic. Given its multidisciplinary approach, combining environmental analysis and engineering, the book offers a valuable resource for all researchers and students interested in environmental chemistry and engineering.
  • Preventing Indoor Bioaerosols Contamination in Food Processing Environments and HVAC-systems: Assessment of Particle Deposition for Hygienic Design Purposes
  • The OASIS Observatory Using Ground-Based Solar Absorption Fourier Transform Infrared Spectroscopy in the Suburbs of Paris (Créteil-France)
  • Daytime Atmospheric Chemistry of C4-C7 Saturated and Unsaturated Carbonyl Compounds
  • Night-time Atmospheric Reactivity of Some Oxygenated Organic Compounds
  • Mercury Soil Pollution in Spain: A Review
  • The Role of Earthworms in Mercury Pollution Soil Assessment
  • Pb-Zn-Cd-As Pollution in Soils Affected by Mining Activities in Central and Southern Spain: a Scattered Legacy Posing Potential Environmental and Health Concerns
  • In Situ Chemical Oxidation Based on Hydrogen Peroxide: Optimization of Its Application to an Hydrocarbon Polluted Site
  • Sustainable Polyurethanes? Chemical Recycling to Get It
  • Polystyrene Wastes, Threat or Opportunity?- Microbial Fuel Cell: the Definitive Technological Approach for Valorizing Organic Wastes?- Removal of Organic Pollutants from Industrial Wastewater by Treatment with Oxidoreductase Enzymes
  • Livestock Waste: Fears and Opportunities
  • Greenhouse Effect Mitigation Through Photocatalytic Technology
  • Microwaves in Green and Sustainable Chemistry.
This volume offers a comprehensive overview of advanced research in the field of environmental green chemistry for air, soil and water pollutants, and presents emerging technologies on the chemical treatment of polluted sites and wastes. The 15 chapters, prepared by internationally respected experts, address the following topics: (1) monitoring of indoor and outdoor air pollutants; (2) atmospheric degradation processes and formation mechanisms of secondary pollutants; (3) the environmental assessment and impacts of soils polluted by heavy metals and hydrocarbons; (4) sustainable and emerging technologies for the chemical treatment of organic and animal wastes and wastewaters; (5) photocatalytic CO2 conversion methods for the mitigation of greenhouse effects; and (6) non-conventional methods in green chemistry synthesis. Lastly, the authors outline the future perspectives of each topic. Given its multidisciplinary approach, combining environmental analysis and engineering, the book offers a valuable resource for all researchers and students interested in environmental chemistry and engineering.
Book
1 online resource (xiii, 131 pages) : illustrations (some color).
  • Theoretical Considerations for Laser Spectroscopy.- Theoretical Considerations for Nuclear Decay Spectroscopy.- Experimental Setup at ISOLDE.- Collinear Resonance Ionization Spectroscopy.- Laser Assisted Nuclear Decay Spectroscopy.- Spectroscopic Studies of neutron-Deficient Francium.- Interpretation of Results.
  • (source: Nielsen Book Data)
This work details an application of collinear resonance ionization spectroscopy for the separation of short-lived isomeric states and their subsequent study with decay spectroscopy. It reports the successful construction of a novel decay spectroscopy apparatus that can operate at pressures below 1 x 10^-9 mbar. The method is demonstrated by separating the nuclear ground and isomeric states of 204Fr and performing alpha-decay spectroscopy. An equivalent mass spectrometer would require 4.6 million times as much resolution to achieve the same result. This work unambiguously confirms the existence of a second isomeric state in 204Fr. The author also demonstrates the effectiveness of this method for laser spectroscopy and identification of hyperfine-structure components with energy tagging. This method was successfully used in 202Fr to identify ground and isomeric states. The measurement of 202Fr reported in this thesis demonstrates a factor of 100 improvement in sensitivity compared to state-of-the-art fluorescence techniques. The work reported in this thesis won the author the IOP Nuclear Physics Group Early Career Prize.
(source: Nielsen Book Data)
  • Theoretical Considerations for Laser Spectroscopy.- Theoretical Considerations for Nuclear Decay Spectroscopy.- Experimental Setup at ISOLDE.- Collinear Resonance Ionization Spectroscopy.- Laser Assisted Nuclear Decay Spectroscopy.- Spectroscopic Studies of neutron-Deficient Francium.- Interpretation of Results.
  • (source: Nielsen Book Data)
This work details an application of collinear resonance ionization spectroscopy for the separation of short-lived isomeric states and their subsequent study with decay spectroscopy. It reports the successful construction of a novel decay spectroscopy apparatus that can operate at pressures below 1 x 10^-9 mbar. The method is demonstrated by separating the nuclear ground and isomeric states of 204Fr and performing alpha-decay spectroscopy. An equivalent mass spectrometer would require 4.6 million times as much resolution to achieve the same result. This work unambiguously confirms the existence of a second isomeric state in 204Fr. The author also demonstrates the effectiveness of this method for laser spectroscopy and identification of hyperfine-structure components with energy tagging. This method was successfully used in 202Fr to identify ground and isomeric states. The measurement of 202Fr reported in this thesis demonstrates a factor of 100 improvement in sensitivity compared to state-of-the-art fluorescence techniques. The work reported in this thesis won the author the IOP Nuclear Physics Group Early Career Prize.
(source: Nielsen Book Data)
Book
1 online resource (379 pages) : illustrations.
Book
1 online resource.
The pace of revolution in analytical chemistry in the field of Geosciences has been dramatic over the recent decades and includes fundamental developments that have become common place in many related and unrelated disciplines. The analytical tools (nano to macro-scale from stable to radioactive isotopes to synchrotron imaging) used have been applied to wide-ranging applications from inorganic to organic geochemistry, biodiversity and chronological tools, to build an understanding of how the Earth system evolved to its present state. This book will provide an essential guide to exploring the earth's natural resources and changing climate by detection science. Individual chapters bring together expertise from across the globe to present a comprehensive outlook on the analytical technologies available to the geoscientist today. Experienced researchers will appreciate the broad treatment of the subject as a valuable reference, while students and those new to the field will quickly gain an appreciation of both the techniques at hand, and the importance of constructing, and analysing, the complex data sets they can generate.
(source: Nielsen Book Data)
The pace of revolution in analytical chemistry in the field of Geosciences has been dramatic over the recent decades and includes fundamental developments that have become common place in many related and unrelated disciplines. The analytical tools (nano to macro-scale from stable to radioactive isotopes to synchrotron imaging) used have been applied to wide-ranging applications from inorganic to organic geochemistry, biodiversity and chronological tools, to build an understanding of how the Earth system evolved to its present state. This book will provide an essential guide to exploring the earth's natural resources and changing climate by detection science. Individual chapters bring together expertise from across the globe to present a comprehensive outlook on the analytical technologies available to the geoscientist today. Experienced researchers will appreciate the broad treatment of the subject as a valuable reference, while students and those new to the field will quickly gain an appreciation of both the techniques at hand, and the importance of constructing, and analysing, the complex data sets they can generate.
(source: Nielsen Book Data)
Book
1 online resource.
Book
1 online resource (xii, 665 pages) : illustrations (some color) Digital: text file; PDF.
  • Live Attenuated Viral Vaccines
  • Inactivated Viral Vaccines
  • Recombinant Virus Like Particle Protein Vaccines
  • Analysis of influenza vaccines
  • Live-attenuated and inactivated whole-cell bacterial vaccines
  • Analytical control strategy of bacterial subunit vaccines
  • Bacterial Polysaccharide Vaccines: Analytical Perspectives
  • Glycoconjugate vaccines
  • Vaccines in research and development: new production platforms and new biomolecular entities for new needs
  • Role of Analytics In Viral Safety
  • Deep Sequencing Applications for Vaccine Development and Safety
  • Quality-by-design: As related to analytical concepts, control and qualification
  • Vaccine Potency Assays
  • Establishing a Shelf-life and Setting Lot-release Specifications
  • Vaccine Reference Standards
  • Lot Release of Vaccines by Regulatory Authorities and Harmonization of Testing Requirements
  • Dendritic cell targeting vaccines.
This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
  • Live Attenuated Viral Vaccines
  • Inactivated Viral Vaccines
  • Recombinant Virus Like Particle Protein Vaccines
  • Analysis of influenza vaccines
  • Live-attenuated and inactivated whole-cell bacterial vaccines
  • Analytical control strategy of bacterial subunit vaccines
  • Bacterial Polysaccharide Vaccines: Analytical Perspectives
  • Glycoconjugate vaccines
  • Vaccines in research and development: new production platforms and new biomolecular entities for new needs
  • Role of Analytics In Viral Safety
  • Deep Sequencing Applications for Vaccine Development and Safety
  • Quality-by-design: As related to analytical concepts, control and qualification
  • Vaccine Potency Assays
  • Establishing a Shelf-life and Setting Lot-release Specifications
  • Vaccine Reference Standards
  • Lot Release of Vaccines by Regulatory Authorities and Harmonization of Testing Requirements
  • Dendritic cell targeting vaccines.
This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
Book
1 online resource.
  • Biomimicry and Materials in Medicine-- Biomimetic Materials and Surfaces in Detection-- Hydrogel-based Molecularly Imprinted Polymers for Biological Detection-- Nanoparticle Technologies in Detection Science-- Smart Indicator Technologies for Chemical and Biochemical Detection-- Supramolecular Chemistry: Calixpyrroles-- Macrocyclics-- Ion and molecularly selective electrodes-- Application of Pattern Recognition Techniques in the Development of Electronic Tongues.
  • (source: Nielsen Book Data)
In a bid to develop synthetic molecules and materials that are capable of mimicking biological recognition and function, intensive research in the fields of synthetic receptor technologies, smart materials, synthetic biology and smart indicators has been under way for the past 20-30 years. The development of synthetic receptors continues to grow rapidly. Novel molecular architectures, with ever improving selective binding properties are constantly being described, and in some cases providing much-needed physical insights into the nature of non-covalent interactions and molecular recognition. Such receptor systems are finding increasingly esoteric applications and this book captures the key developments at the synthetic receptor/biology/detection science interface. The editor has extensive experience in applying smart materials and synthetic receptors to the development of biosensors. Reddy has developed smart, permselective and biocompatible molecularly imprinted polymers and membrane materials for the sensor/sample interface and the advancement of smart materials-based electrochemical, quartz crystal and optical sensors for medical, food and environmental applications. Chapters demonstrate how growing disciplines such as biomimetics, synthetic receptor technologies, pattern recognition and nanotechnology are being used to develop new smart materials for diagnostic sensor and biosensor applications. Postgraduate students and researchers in academia and industry will benefit from this resourceful handbook.
(source: Nielsen Book Data)
  • Biomimicry and Materials in Medicine-- Biomimetic Materials and Surfaces in Detection-- Hydrogel-based Molecularly Imprinted Polymers for Biological Detection-- Nanoparticle Technologies in Detection Science-- Smart Indicator Technologies for Chemical and Biochemical Detection-- Supramolecular Chemistry: Calixpyrroles-- Macrocyclics-- Ion and molecularly selective electrodes-- Application of Pattern Recognition Techniques in the Development of Electronic Tongues.
  • (source: Nielsen Book Data)
In a bid to develop synthetic molecules and materials that are capable of mimicking biological recognition and function, intensive research in the fields of synthetic receptor technologies, smart materials, synthetic biology and smart indicators has been under way for the past 20-30 years. The development of synthetic receptors continues to grow rapidly. Novel molecular architectures, with ever improving selective binding properties are constantly being described, and in some cases providing much-needed physical insights into the nature of non-covalent interactions and molecular recognition. Such receptor systems are finding increasingly esoteric applications and this book captures the key developments at the synthetic receptor/biology/detection science interface. The editor has extensive experience in applying smart materials and synthetic receptors to the development of biosensors. Reddy has developed smart, permselective and biocompatible molecularly imprinted polymers and membrane materials for the sensor/sample interface and the advancement of smart materials-based electrochemical, quartz crystal and optical sensors for medical, food and environmental applications. Chapters demonstrate how growing disciplines such as biomimetics, synthetic receptor technologies, pattern recognition and nanotechnology are being used to develop new smart materials for diagnostic sensor and biosensor applications. Postgraduate students and researchers in academia and industry will benefit from this resourceful handbook.
(source: Nielsen Book Data)
Book
xvi, 600 pages : illustrations (some color) ; 24 cm
  • Mass spectrometry for proteomics-based investigation / Alisa G. Woods, Izabela Sokolowska, Armand G. Ngounou Wetie, Kelly Wormwood, Roshanak Aslebagh, Sapan Patel, and Costel C. Darie
  • MALDI profiling and applications in medicine / Ed Dudley
  • Simplifying the proteome: analytical strategies for improving peak capacity / Lee A. Gethings and Joanne B. Connolly
  • Quantitative shotgun proteomics with data-independent acquisition and traveling wave ion mobility spectrometry: a versatile tool in the life sciences / Lewis M. Brown
  • Stable isotope labeling by amino acids in cell culture (SILAC) for quantitative proteomics / Esthelle Hoedt, Guoan Zhang, and Thomas A. Neubert
  • Utility of computational structural biology in mass spectrometry / Urmi Roy, Alisa G. Woods, Izabela Sokolowska, and Costel C. Darie
  • Affinity-mass spectrometry approaches for elucidating structures and interactions of protein-ligand complexes / Brînduşa Alina Petre
  • Neurological analyses: focus on gangliosides and mass spectrometry / Alina D. Zamfir
  • Mass spectrometric analysis of post-translational modifications (PTMs) and protein-protein interactions (PPIs) / Armand G. Ngounou Wetie, Alisa G. Woods, and Costel C. Darie
  • Applications for mass spectrometry in the study of ion channel structure and function / Damien S.K. Samways
  • A mass spectrometry view of stable and transient protein interactions / Hanna G. Budayeva and Ileana M. Cristea
  • Mass spectrometry-based tissue imaging of small molecules / Carly N. Ferguson, Joseph W.M. Fowler, Jonathan F. Waxer, Richard A. Gatti, and Joseph A. Loo
  • Redox proteomics: from bench to bedside / Karina Ckless
  • Analysis of fluorinated proteins by mass spectrometry / Linda A. Luck
  • Mass spectrometry for proteomics-based investigation using the zebrafish vertebrate model system / Reshica Baral, Armand G. Ngounou Wetie, Costel C. Darie, and Kenneth N. Wallace
  • Mass spectrometry-based biomarkers in drug development / Ronald A. Miller and Daniel S. Spellman
  • Detection of biomedically relevant stilbenes from wines by mass spectrometry / Veronica Andrei, Armand G. Ngounou Wetie, Iuliana Mihai, Costel C. Darie, and Alina Vasilescu
  • Mass spectrometric DNA adduct quantification by multiple reaction monitoring and its future use for the molecular epidemiology of cancer / Bernhard H. Monien
  • Using breast milk to assess breast cancer risk: the role of mass spectrometry-based proteomics / Sallie S. Schneider, Roshanak Aslebagh, Armand G. Ngounou Wetie, Susan R. Sturgeon, Costel C. Darie, and Kathleen F. Arcaro
  • Cancer secretomes and their place in supplementing other hallmarks of cancer / Sapan Patel, Armand G. Ngounou Wetie, Costel C. Darie, and Bayard D. Clarkson
  • Thiostrepton, a natural compound that triggers heat shock response and apoptosis in human cancer cells: a proteomics investigation / Cristinel Sandu, Armand G. Ngounou Wetie, Costel C. Darie, and Hermann Steller
  • Using proteomics to unravel the mysterious steps of the HBV-life-cycle / Norica Branza-Nichita, Catalina Petrareanu, Catalin Lazar, Izabela Sokolowska, and Costel C. Darie
  • Oxidative stress and antibiotic resistance in bacterial pathogens: state of the art, methodologies, and future trends / Mouna Marrakchi, Xiaobo Liu, and Silvana Andreescu
  • Proteomic approaches to dissect neuronal signaling pathways / Heather L. Bowling and Katrin Deinhardt
  • Investigating a Novel Protein Using Mass Spectrometry: The Example of Tumor Differentiation Factor (TDF) / Alisa G. Woods, Izabela Sokolowska, Katrin Deinhardt, and Costel C. Darie
  • Mass spectrometry for the study of autism and neurodevelopmental disorders / Armand G. Ngounou Wetie, Robert M. Dekroon, Mihaela Mocanu, Jeanne P. Ryan, Costel C. Darie, and Alisa G. Woods
  • Biomarkers in major depressive disorder: the role of mass spectrometry / Alisa G. Woods, Dan V. Iosifescu, and Costel C. Darie
  • Application of mass spectrometry to characterize localization and efficacy of nanoceria in vivo / Karin L. Heckman, Joseph Erlichman, Ken Reed, and Matthew Skeels
  • Bottlenecks in proteomics / Armand G. Ngounou Wetie, Devon A. Shipp, and Costel C. Darie.
"This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine"--Publisher's description.
  • Mass spectrometry for proteomics-based investigation / Alisa G. Woods, Izabela Sokolowska, Armand G. Ngounou Wetie, Kelly Wormwood, Roshanak Aslebagh, Sapan Patel, and Costel C. Darie
  • MALDI profiling and applications in medicine / Ed Dudley
  • Simplifying the proteome: analytical strategies for improving peak capacity / Lee A. Gethings and Joanne B. Connolly
  • Quantitative shotgun proteomics with data-independent acquisition and traveling wave ion mobility spectrometry: a versatile tool in the life sciences / Lewis M. Brown
  • Stable isotope labeling by amino acids in cell culture (SILAC) for quantitative proteomics / Esthelle Hoedt, Guoan Zhang, and Thomas A. Neubert
  • Utility of computational structural biology in mass spectrometry / Urmi Roy, Alisa G. Woods, Izabela Sokolowska, and Costel C. Darie
  • Affinity-mass spectrometry approaches for elucidating structures and interactions of protein-ligand complexes / Brînduşa Alina Petre
  • Neurological analyses: focus on gangliosides and mass spectrometry / Alina D. Zamfir
  • Mass spectrometric analysis of post-translational modifications (PTMs) and protein-protein interactions (PPIs) / Armand G. Ngounou Wetie, Alisa G. Woods, and Costel C. Darie
  • Applications for mass spectrometry in the study of ion channel structure and function / Damien S.K. Samways
  • A mass spectrometry view of stable and transient protein interactions / Hanna G. Budayeva and Ileana M. Cristea
  • Mass spectrometry-based tissue imaging of small molecules / Carly N. Ferguson, Joseph W.M. Fowler, Jonathan F. Waxer, Richard A. Gatti, and Joseph A. Loo
  • Redox proteomics: from bench to bedside / Karina Ckless
  • Analysis of fluorinated proteins by mass spectrometry / Linda A. Luck
  • Mass spectrometry for proteomics-based investigation using the zebrafish vertebrate model system / Reshica Baral, Armand G. Ngounou Wetie, Costel C. Darie, and Kenneth N. Wallace
  • Mass spectrometry-based biomarkers in drug development / Ronald A. Miller and Daniel S. Spellman
  • Detection of biomedically relevant stilbenes from wines by mass spectrometry / Veronica Andrei, Armand G. Ngounou Wetie, Iuliana Mihai, Costel C. Darie, and Alina Vasilescu
  • Mass spectrometric DNA adduct quantification by multiple reaction monitoring and its future use for the molecular epidemiology of cancer / Bernhard H. Monien
  • Using breast milk to assess breast cancer risk: the role of mass spectrometry-based proteomics / Sallie S. Schneider, Roshanak Aslebagh, Armand G. Ngounou Wetie, Susan R. Sturgeon, Costel C. Darie, and Kathleen F. Arcaro
  • Cancer secretomes and their place in supplementing other hallmarks of cancer / Sapan Patel, Armand G. Ngounou Wetie, Costel C. Darie, and Bayard D. Clarkson
  • Thiostrepton, a natural compound that triggers heat shock response and apoptosis in human cancer cells: a proteomics investigation / Cristinel Sandu, Armand G. Ngounou Wetie, Costel C. Darie, and Hermann Steller
  • Using proteomics to unravel the mysterious steps of the HBV-life-cycle / Norica Branza-Nichita, Catalina Petrareanu, Catalin Lazar, Izabela Sokolowska, and Costel C. Darie
  • Oxidative stress and antibiotic resistance in bacterial pathogens: state of the art, methodologies, and future trends / Mouna Marrakchi, Xiaobo Liu, and Silvana Andreescu
  • Proteomic approaches to dissect neuronal signaling pathways / Heather L. Bowling and Katrin Deinhardt
  • Investigating a Novel Protein Using Mass Spectrometry: The Example of Tumor Differentiation Factor (TDF) / Alisa G. Woods, Izabela Sokolowska, Katrin Deinhardt, and Costel C. Darie
  • Mass spectrometry for the study of autism and neurodevelopmental disorders / Armand G. Ngounou Wetie, Robert M. Dekroon, Mihaela Mocanu, Jeanne P. Ryan, Costel C. Darie, and Alisa G. Woods
  • Biomarkers in major depressive disorder: the role of mass spectrometry / Alisa G. Woods, Dan V. Iosifescu, and Costel C. Darie
  • Application of mass spectrometry to characterize localization and efficacy of nanoceria in vivo / Karin L. Heckman, Joseph Erlichman, Ken Reed, and Matthew Skeels
  • Bottlenecks in proteomics / Armand G. Ngounou Wetie, Devon A. Shipp, and Costel C. Darie.
"This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine"--Publisher's description.
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Check Medical Library (Lane) catalog for status
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Book
1 online resource (xvi, 600 pages) : illustrations (some color).
Book
1 online resource.
  • Introduction to Biological Solid-State NMR-- Combining NMR Spectroscopic Measurements and Molecular Dynamics Simulations to Determine the Orientation of Amphipathic Peptides in Lipid Bilayers-- 13C-13C Distance Measurements by Polarisation Transfer Matrix Analysis of 13C Spin Diffusion in Uniformly 13C-Labeled Molecular Complex under Magic Angle Spinning-- Demonstration of the Equivalence of Solid-state NMR Orientational Constraints from Magnetic and Rotational Alignment of the Coat Protein in a Filamentous Bacteriophage-- Membrane Protein Interactions-- Magnetic liposomes and bicelles: new tools for membrane-peptides structural studies-- Membranes and Their Lipids: A Molecular Insight into Their Organization and Function-- Structural studies of small bioactive compounds interacting with membranes and proteins-- Lipopolysaccharide Induces Raft Domain Expansion in a Cholesterol-Containing Membrane-- Deuterium NMR of mixed lipid membranes-- Membrane Interactions of Amphiphilic Peptides with Antimicrobial Potential: A Solid-State NMR Study-- Investigations of the structure, topology and dynamics of membrane-associated polypeptides by solid-state NMR spectroscopy-- NMR of Lipids and Lipid/Peptide Mixtures-- NMR investigations of the structure and dynamics of antimicrobial peptides: The peptaibol alamethicin-- Solid-state NMR studies of antimicrobial peptide interactions with specific lipid environments-- Dynamic Structure Analysis of Peptides in Membranes by Solid-State NMR-- Structural Dynamics of Retinal in Rhodopsin Activation Viewed by Solid-State 2H NMR Spectroscopy-- Helical Membrane Protein Structure: Strategy for Success-- Chemistry and Structure via Solid-State NMR-- Photoactivated Structural Changes in Photoreceptor Membrane Proteins as Revealed by in situ Photoirradiation Solid-State NMR Spectroscopy-- A Promising Prognosis for Solid-State NMR of Functional Membrane Protein Complexes-- Structural Topologies of Phosphorylated and Non-phosphorylated Oligomeric Phospholamban in Lipid Membranes by Hybrid NMR Approach-- Structural Insights from solid-state NMR into the Function of the Bacteriorhodopsin Photoreceptor Protein-- 2H solid-state NMR study of peptide-membrane interactions in intact bacteria-- Magic Angle Spinning NMR Spectroscopy for Resolving Structure and Mechanisms of Function of Membrane Protein Assemblies Involved in Photosynthetic Energy Conversio-- Large protein complexes revealed by solution state NMR: G Proteins and G Protein-activated inwardly rectifying potassium ion channel (GIRK)-- NMR studies of small molecules interacting with amyloidogenic proteins-- Solid-State NMR Studies of ss-Amyloid Fibrils and Related Assemblies-- Subject Index.
  • (source: Nielsen Book Data)
The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation. Advances in Biological Solid-State NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid-state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis. Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid-state NMR. A thorough and comprehensive discussion of this promising technique follows, which will be essential reading for those working or studying at postgraduate level in this exciting field.
(source: Nielsen Book Data)
  • Introduction to Biological Solid-State NMR-- Combining NMR Spectroscopic Measurements and Molecular Dynamics Simulations to Determine the Orientation of Amphipathic Peptides in Lipid Bilayers-- 13C-13C Distance Measurements by Polarisation Transfer Matrix Analysis of 13C Spin Diffusion in Uniformly 13C-Labeled Molecular Complex under Magic Angle Spinning-- Demonstration of the Equivalence of Solid-state NMR Orientational Constraints from Magnetic and Rotational Alignment of the Coat Protein in a Filamentous Bacteriophage-- Membrane Protein Interactions-- Magnetic liposomes and bicelles: new tools for membrane-peptides structural studies-- Membranes and Their Lipids: A Molecular Insight into Their Organization and Function-- Structural studies of small bioactive compounds interacting with membranes and proteins-- Lipopolysaccharide Induces Raft Domain Expansion in a Cholesterol-Containing Membrane-- Deuterium NMR of mixed lipid membranes-- Membrane Interactions of Amphiphilic Peptides with Antimicrobial Potential: A Solid-State NMR Study-- Investigations of the structure, topology and dynamics of membrane-associated polypeptides by solid-state NMR spectroscopy-- NMR of Lipids and Lipid/Peptide Mixtures-- NMR investigations of the structure and dynamics of antimicrobial peptides: The peptaibol alamethicin-- Solid-state NMR studies of antimicrobial peptide interactions with specific lipid environments-- Dynamic Structure Analysis of Peptides in Membranes by Solid-State NMR-- Structural Dynamics of Retinal in Rhodopsin Activation Viewed by Solid-State 2H NMR Spectroscopy-- Helical Membrane Protein Structure: Strategy for Success-- Chemistry and Structure via Solid-State NMR-- Photoactivated Structural Changes in Photoreceptor Membrane Proteins as Revealed by in situ Photoirradiation Solid-State NMR Spectroscopy-- A Promising Prognosis for Solid-State NMR of Functional Membrane Protein Complexes-- Structural Topologies of Phosphorylated and Non-phosphorylated Oligomeric Phospholamban in Lipid Membranes by Hybrid NMR Approach-- Structural Insights from solid-state NMR into the Function of the Bacteriorhodopsin Photoreceptor Protein-- 2H solid-state NMR study of peptide-membrane interactions in intact bacteria-- Magic Angle Spinning NMR Spectroscopy for Resolving Structure and Mechanisms of Function of Membrane Protein Assemblies Involved in Photosynthetic Energy Conversio-- Large protein complexes revealed by solution state NMR: G Proteins and G Protein-activated inwardly rectifying potassium ion channel (GIRK)-- NMR studies of small molecules interacting with amyloidogenic proteins-- Solid-State NMR Studies of ss-Amyloid Fibrils and Related Assemblies-- Subject Index.
  • (source: Nielsen Book Data)
The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation. Advances in Biological Solid-State NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid-state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis. Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid-state NMR. A thorough and comprehensive discussion of this promising technique follows, which will be essential reading for those working or studying at postgraduate level in this exciting field.
(source: Nielsen Book Data)
Book
1 online resource (vii, 264 pages) : illustrations (some color).
Book
1 online resource : text file, PDF
  • Preface Methodologies on Quantum-Chemical Calculation Reactivity of tert.butyl ester 3-(3 ', 5 '-di-tert.butyl-4 '-hydroxyphenyl)-Propionic Acid in the Reactions of Oxidation Assessment of the Potential of Enhanced Oil Recovery from Reservoirs with High Water Content Using the Heat of Nitrate Oxidation Reactions and In Situ Hydrocarbon Oxidation Antioxidative Efficiency Terpenphenol at Thermo-Oxidative Degradation Polyvinyl Chloride Photoinitiated Copolymerization of Bifunctional (Meth)Acrylates. Kinetics and Mechanism Nanofibrous on the Base of Polyhydroxybutyrate Degradation of Some Films Under UV-Radiation Polyolefin Chlorine-Containing Rubbers: Properties and Applications Adhesion Characteristics of Ethylene Copolymers Oxidation of Fibrinogen by Ozone: Effect of Dihydroquercetin and Cyclodextrin Inclusion Complex with the New Dihydroquercetin Derivative Industrial Drying and Evaporation Systems Nanopatterned Implants Loaded with Drugs Index.
  • (source: Nielsen Book Data)
In a unified treatment for the broad subject of materials, this book presents some fascinating phenomena associated with the remarkable performance of polymers and chemical materials. It provides a comprehensive description of the applications and tools for chemical polymeric materials. It also includes the background information necessary for assimilating the current academic literature on complex materials and their applications.
(source: Nielsen Book Data)
  • Preface Methodologies on Quantum-Chemical Calculation Reactivity of tert.butyl ester 3-(3 ', 5 '-di-tert.butyl-4 '-hydroxyphenyl)-Propionic Acid in the Reactions of Oxidation Assessment of the Potential of Enhanced Oil Recovery from Reservoirs with High Water Content Using the Heat of Nitrate Oxidation Reactions and In Situ Hydrocarbon Oxidation Antioxidative Efficiency Terpenphenol at Thermo-Oxidative Degradation Polyvinyl Chloride Photoinitiated Copolymerization of Bifunctional (Meth)Acrylates. Kinetics and Mechanism Nanofibrous on the Base of Polyhydroxybutyrate Degradation of Some Films Under UV-Radiation Polyolefin Chlorine-Containing Rubbers: Properties and Applications Adhesion Characteristics of Ethylene Copolymers Oxidation of Fibrinogen by Ozone: Effect of Dihydroquercetin and Cyclodextrin Inclusion Complex with the New Dihydroquercetin Derivative Industrial Drying and Evaporation Systems Nanopatterned Implants Loaded with Drugs Index.
  • (source: Nielsen Book Data)
In a unified treatment for the broad subject of materials, this book presents some fascinating phenomena associated with the remarkable performance of polymers and chemical materials. It provides a comprehensive description of the applications and tools for chemical polymeric materials. It also includes the background information necessary for assimilating the current academic literature on complex materials and their applications.
(source: Nielsen Book Data)
Book
1 online resource (xvii, 330 pages) : illustrations (some color).
Book
1 online resource (x, 331 pages) : illustrations (some color).

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